Background
Methods
Data sources
Study population
Outcomes
Priority groups for vaccination
JCVI risk group | Priority group | |
---|---|---|
Description | Name | |
1 | Residents in a care home for older adults, aged 65+ | Care home |
2 | All those 80 years of age and over | 80+ |
Health and social care workers | Health/care workers | |
3 | All those 70 years of age and over | 70–79 |
4 | Clinically extremely vulnerable individuals | CEV |
5, 7, 8, 9 | All those 50 years of age and over | 50-69 |
6 | “At Risk” individuals, some misclassified health/care workers and care home residents (except those age 70+ or shielding who will be included in another group), carers, household contacts of those at increased risk, and those not in priority groups who had the vaccine opportunistically, e.g. by responding to calls to use up excess doses. | Others not in the above groups |
Key demographic and clinical characteristics
Codelists and implementationg
Missing data
Statistical methods
Software and reproducibility
Patient and public involvement
Results
Study population
Priority group | Fully vaccinated | Positive SARS-CoV-2 testa | COVID-19-related hospital admissiona | COVID-19-related critical care admissionaa | COVID-19-related deatha | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Countb | Follow-up time, medium days (IQR) | Tests conducted (%)c | Positivity (%) | Eventsb (PYs) | Incidence rate per 1000 person-years (95% CI) | Eventsb (PYs) | Incidence rate per 1000 person-years (95% CI) | Eventsb (PYs) | Incidence rate per 1000 person-years (95% CI) | Eventsb (PYs) | Incidence rate per 1000 person-years (95% CI) | ||||
0 | 1 | 2 | 3+ | ||||||||||||
All | 15,501,550 | 149 (107–179) | 46 | 19 | 10 | 19 | 579,780 (5,912,498) | 3.17 | 98.06 (97.93–98.19) | 28,580 (,5993,535) | 4.77 (4.74–4.8) | 1980 (5996007) | 0.33 (0.32–0.34) | 6435 (5,996,178) | 1.07 (1.06–1.09) |
Care home (priority group 1) | 98,400 | 200 (180–207) | 9 | 5 | 4 | 82 | 3110 (48,207) | 0.90 | 64.51 (63.37–65.68) | 755 (48,600) | 15.58 (15.02–16.15) | REDACTED | REDACTED | 650 (48,674) | 13.37 (12.86–13.91) |
80+ (priority group 2) | 1,073,145 | 200 (191–213) | 59 | 14 | 7 | 20 | 15,945 (597,368) | 1.96 | 26.69 (26.48–26.9) | 7545 (598,868) | 12.60 (12.45–12.74) | 180 (599,613) | 0.30 (0.28–0.32) | 2785 (599,626) | 4.64 (4.56–4.73) |
Health/care workers (priority groups 1–2) | 555,820 | 200 (182–211) | 27 | 21 | 14 | 39 | 30,045 (282,813) | 3.31 | 106.23 (105.62–106.84) | 440 (287,822) | 1.53 (1.46–1.60) | 30 (287,862) | 0.10 (0.08–0.12) | 20 (287,866) | 0.07 (0.05–0.08) |
70–79 (priority groups 3–4) | 1,990,755 | 184 (176–191) | 56 | 17 | 8 | 19 | 41,325 (985,544) | 2.16 | 41.93 (41.73–42.14) | 6875 (990,497) | 6.94 (6.86–7.03) | 525 (991,111) | 0.53 (0.51–0.56) | 1640 (991,147) | 1.66 (1.62–1.70) |
CEV (age 16–69) (priority group 4) | 725,045 | 171 (157–181) | 42 | 18 | 10 | 30 | 34,820 (322,885) | 2.92 | 107.84 (107.27–108.42) | 4560 (327,932) | 13.90 (13.7–14.11) | 565 (328,308) | 1.73 (1.66–1.80) | 785 (328,361) | 2.39 (2.31–2.48) |
50–69 (priority groups 5–9) | 4,730,155 | 151 (138–166) | 47 | 18 | 9 | 26 | 184,890 (1,946,451) | 2.27 | 94.99 (94.77–95.21) | 5075 (1,973,346) | 2.57 (2.54–2.61) | 515 (1,973,743) | 0.26 (0.25–0.27) | 495 (1,973,791) | 0.25 (0.24–0.26) |
Others not in the above groupsd | 15,501,550 | 149 (107–179) | 46 | 19 | 10 | 19 | 579,780 (5,912,498) | 3.17 | 98.06 (97.93–98.19) | 28,580 (5,993,535) | 4.77 (4.74–4.80) | 1980 (5,996,007) | 0.33 (0.32–0.34) | 6435 (5,996,178) | 1.07 (1.06–1.09) |
Positive SARS-CoV-2 test
Clinical/demographic group | Category | Fully vaccinated | Positive SARS-CoV-2 testa | Hospitalised with COVID-19a | COVID-19-related critical care admissiona | COVID-19 related deatha | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Countab | Follow-up time, medium days (IQR) | Tests conducted (%)c | Positivity (%) | Eventsab (PYs) | Incidence rate per 1000 person-years (95% CI) | Eventsab (PYs) | Incidence rate per 1000 person-years (95% CI) | Eventsab (PYs) | Incidence rate per 1000 person-years (95% CI) | Eventsab (PYs) | Incidence rate per 1000 person-years (95% CI) | |||||
0 | 1 | 2 | 3+ | |||||||||||||
Age | 16–29 | 2,227,120 | 66 (47–129) | 45 | 21 | 11 | 22 | 63,620 (516,289) | 5.47 | 123.22 (122.74–123.71) | 1000 (527,073) | 1.90 (1.84–1.96) | 40 (527,145) | 0.07 (0.06–0.08) | 10 (527,150) | 0.02 (0.01–0.02) |
30–39 | 2,289,165 | 94 (72–145) | 42 | 21 | 12 | 25 | 93,375 (660,313) | 4.50 | 141.41 (140.95–141.88) | 1550 (673,014) | 2.30 (2.25–2.36) | 80 (673,118) | 0.12 (0.10–0.13) | 35 (673,127) | 0.05 (0.04–0.06) | |
40–50 | 2,459,075 | 126 (103–155) | 40 | 20 | 11 | 29 | 153,210 (851,368) | 3.86 | 179.96 (179.5–180.42) | 2320 (871,625) | 2.66 (2.61–2.72) | 210 (871,799) | 0.24 (0.22–0.26) | 120 (871,821) | 0.14 (0.12–0.15) | |
50–59 | 2,942,440 | 146 (135–163) | 43 | 19 | 10 | 28 | 136,470 (1,188,958) | 2.49 | 114.78 (114.47–115.09) | 3850 (1,209,351) | 3.18 (3.13–3.23) | 420 (1,209,663) | 0.35 (0.33–0.37) | 370 (1,209,705) | 0.31 (0.29–0.32) | |
60–69 | 2,421,245 | 163 (150–174) | 49 | 18 | 9 | 24 | 72,735 (1,064,063) | 1.94 | 68.36 (68.1–68.61) | 4715 (1,074,117) | 4.39 (4.33–4.45) | 530 (1,074,498) | 0.49 (0.47–0.52) | 845 (1,074,542) | 0.78 (0.76–0.81) | |
70–79 | 2,016,365 | 184 (176–191) | 56 | 17 | 8 | 19 | 42,075 (998433) | 2.11 | 42.14 (41.93–42.34) | 7050 (1,003,480) | 7.03 (6.94–7.11) | 530 (1,004,114) | 0.53 (0.51–0.55) | 1720 (1,004,149) | 1.71 (1.67–1.76) | |
80 + | 1,146,150 | 200 (191–213) | 55 | 14 | 7 | 24 | 18,295 (633,074) | 1.72 | 28.9 (28.69–29.11) | 8095 (634,874) | 12.75 (12.61–12.89) | 180 (635670) | 0.29 (0.27–0.31) | 3345 (635,683) | 5.26 (5.17–5.35) | |
Sex | Female | 8,072,115 | 155 (116–184) | 43 | 19 | 10 | 28 | 326,565 (3,182,819) | 2.69 | 102.6 (102.42–102.78) | 13,500 (3,228,984) | 4.18 (4.14–4.22) | 740 (3,230,164) | 0.23 (0.22–0.24) | 2655 (3,230,233) | 0.82 (0.81–0.84) |
Male | 7,429,435 | 144 (99–174) | 50 | 19 | 10 | 21 | 253,215 (2,729,679) | 4.04 | 92.76 (92.58–92.95) | 15,080 (2,764,551) | 5.46 (5.41–5.50) | 1250 (2,765,843) | 0.45 (0.44–0.46) | 3780 (2,765,945) | 1.37 (1.34–1.39) | |
BMI (kg/m2) | Not obese | 12,078,955 | 145 (98–178) | 46 | 19 | 10 | 25 | 429,315 (4,498,201) | 3.20 | 95.44 (95.3–95.59) | 18,330 (4,558,086) | 4.02 (3.99–4.05) | 1010 (4,559,694) | 0.22 (0.21–0.23) | 4475 (4,559,783) | 0.98 (0.97–1.00) |
Obese (>30) | 3,422,600 | 159 (135–181) | 46 | 19 | 10 | 26 | 150,465 (1,414,297) | 3.07 | 106.39 (106.11–106.66) | 10,255 (1,435,449) | 7.14 (7.07–7.21) | 980 (1,436,313) | 0.68 (0.66–0.71) | 1965 (1,436,395) | 1.37 (1.34–1.40) | |
Smoking | Non-smoker and unknown | 7,833,690 | 143 (91–176) | 45 | 19 | 10 | 26 | 291,000 (2,835,776) | 3.19 | 102.62 (102.43–102.81) | 9960 (2,876,640) | 3.46 (3.43–3.50) | 675 (2,877,506) | 0.24 (0.23–0.24) | 1860 (2,877,571) | 0.65 (0.63–0.66) |
Current and former | 7,667,865 | 156 (125–182) | 47 | 19 | 10 | 24 | 288,780 (3,076,722) | 3.14 | 93.86 (93.68–94.03) | 18,620 (3,116,894) | 5.97 (5.93–6.02) | 1310 (3,118,501) | 0.42 (0.41–0.43) | 4575 (3,118,607) | 1.47 (1.45–1.49) | |
Ethnicity | White | 11,895,195 | 154 (119–182) | 44 | 19 | 10 | 26 | 466,170 (4,688,366) | 3.08 | 99.43 (99.29–99.58) | 25,500 (4,753,382) | 5.36 (5.33–5.40) | 1760 (4,755,592) | 0.37 (0.36–0.38) | 5905 (4,755,742) | 1.24 (1.23–1.26) |
Mixed | 151,275 | 129 (76–164) | 44 | 20 | 11 | 25 | 4980 (50,030) | 3.78 | 99.56 (98.16–100.98) | 195 (50,764) | 3.82 (3.56–4.11) | 20 (50,779) | 0.35 (0.28–0.45) | 25 (50,780) | 0.51 (0.42–0.62) | |
Asian or Asian British | 901,520 | 134 (81–170) | 55 | 19 | 10 | 17 | 29,830 (309,199) | 4.24 | 96.48 (95.92–97.04) | 1735 (313,404) | 5.54 (5.40–5.67) | 120 (313,565) | 0.39 (0.36–0.43) | 300 (313,577) | 0.95 (0.90–1.01) | |
Black or Black British | 224,740 | 138 (87–172) | 49 | 18 | 9 | 23 | 5930 (78,696) | 2.98 | 75.37 (74.39–76.35) | 415 (79,581) | 5.20 (4.95–5.46) | 25 (79,614) | 0.34 (0.28–0.41) | 50 (79,616) | 0.63 (0.55–0.72) | |
Other ethnic groups | 242,335 | 122 (79–159) | 50 | 19 | 10 | 20 | 5970 (78,690) | 3.66 | 75.85 (74.88–76.84) | 295 (79,509) | 3.69 (3.48–3.91) | 30 (79,531) | 0.38 (0.31–0.45) | 55 (79,534) | 0.67 (0.58–0.76) | |
Unknown | 2,086,480 | 135 (82–164) | 53 | 18 | 9 | 21 | 66,900 (707,517) | 3.36 | 94.56 (94.19–94.92) | 445 (716,894) | 0.62 (0.59–0.65) | 30 (716,926) | 0.04 (0.03–0.05) | 105 (716,928) | 0.14 (0.13–0.16) | |
IMD quintile | 1 (most deprived) | 2,519,265 | 146 (100–176) | 54 | 18 | 9 | 20 | 96,800 (927,354) | 3.56 | 104.39 (104.05–104.72) | 6890 (941,680) | 7.32 (7.23–7.41) | 460 (942,314) | 0.49 (0.46–0.51) | 1535 (942,355) | 1.63 (1.59–1.67) |
2 | 2,871,570 | 148 (101–178) | 49 | 19 | 9 | 23 | 105,430 (1,074,696) | 3.30 | 98.10 (97.80–98.4) | 5860 (1,089,699) | 5.38 (5.31–5.45) | 410 (1,090,201) | 0.38 (0.36–0.39) | 1310 (1,090,236) | 1.20 (1.17–1.23) | |
3 | 3,318,680 | 150 (109–180) | 46 | 19 | 10 | 25 | 119,680 (1,274,137) | 3.06 | 93.93 (93.66–94.2) | 5595 (1,290,631) | 4.33 (4.28–4.39) | 390 (1,291,108) | 0.30 (0.29–0.32) | 1265 (1,291,143) | 0.98 (0.95–1.01) | |
4 | 3,274,460 | 151 (113–181) | 44 | 19 | 10 | 27 | 121,740 (1,272,731) | 3.07 | 95.65 (95.38–95.93) | 5210 (1,289,336) | 4.04 (3.98–4.10) | 380 (1,289,775) | 0.29 (0.28–0.31) | 1195 (1,289,806) | 0.92 (0.90–0.95) | |
5 (least deprived) | 3,115,025 | 152 (115–181) | 41 | 19 | 11 | 29 | 120,245 (1,220,876) | 2.98 | 98.49 (98.21–98.77) | 4395 (1,237,218) | 3.55 (3.50–3.61) | 310 (1,237,580) | 0.25 (0.24–0.26) | 1020 (1,237,606) | 0.82 (0.80–0.85) | |
Unknown | 402,555 | 139 (87–173) | 43 | 20 | 11 | 26 | 15,885 (142,704) | 3.64 | 111.31 (110.43–112.19) | 635 (144,971) | 4.37 (4.20–4.55) | 45 (145,029) | 0.30 (0.25–0.35) | 120 (145,032) | 0.82 (0.75–0.90) | |
Region | London | 891,660 | 129 (83–170) | 40 | 20 | 12 | 28 | 21,970 (304,836) | 4.19 | 72.07 (71.59–72.56) | 1100 (308,097) | 3.57 (3.46–3.68) | 70 (308,184) | 0.23 (0.21–0.26) | 220 (308,190) | 0.72 (0.67–0.77) |
East of England | 3,629,745 | 149 (104–179) | 44 | 19 | 10 | 27 | 113,725 (1,380,061) | 2.82 | 82.41 (82.16–82.65) | 5105 (1,394,975) | 3.66 (3.61–3.71) | 410 (1,395,387) | 0.29 (0.28–0.31) | 1215 (1,395,416) | 0.87 (0.84–0.89) | |
Region (continued) | East Midlands | 2,702,030 | 150 (113–177) | 48 | 19 | 10 | 24 | 108,255 (1,029,678) | 3.47 | 105.14 (104.82–105.46) | 5480 (1,044,633) | 5.24 (5.17–5.32) | 420 (1,045,072) | 0.4 (0.38–0.42) | 1215 (1,045,111) | 1.16 (1.13–1.20) |
North East | 745,775 | 150 (115–181) | 49 | 20 | 10 | 22 | 37,590 (289,494) | 4.54 | 129.85 (129.18–130.52) | 2170 (294,874) | 7.36 (7.21–7.52) | 140 (295,080) | 0.47 (0.43–0.51) | 495 (295,093) | 1.68 (1.61–1.76) | |
North West | 1,402,645 | 150 (115–180) | 49 | 19 | 9 | 23 | 63,570 (541,871) | 3.55 | 117.32 (116.85–117.78) | 3445 (551,601) | 6.24 (6.14–6.35) | 265 (551,937) | 0.48 (0.45–0.51) | 780 (551,962) | 1.42 (1.37–1.47) | |
South East | 1,078,015 | 151 (108–180) | 43 | 19 | 10 | 27 | 34,655 (417,431) | 2.65 | 83.02 (82.58–83.47) | 1715 (422,133) | 4.06 (3.96–4.16) | 110 (422,262) | 0.27 (0.24–0.29) | 370 (422,271) | 0.88 (0.84–0.93) | |
South West | 2,314,235 | 152 (111–180) | 45 | 19 | 10 | 27 | 83,030 (896,729) | 2.56 | 92.59 (92.27–92.91) | 3460 (907,535) | 3.81 (3.75–3.88) | 185 (907,805) | 0.20 (0.19–0.22) | 760 (907,822) | 0.83 (0.81–0.87) | |
West Midlands | 548,600 | 149 (109–179) | 52 | 18 | 9 | 22 | 21,340 (208,833) | 3.69 | 102.19 (101.49–102.89) | 1425 (212,055) | 6.73 (6.55–6.91) | 105 (212,201) | 0.50 (0.45–0.55) | 300 (212,211) | 1.40 (1.33–1.49) | |
Yorkshire and The Humber | 2,179,520 | 151 (111–181) | 50 | 19 | 9 | 22 | 95,360 (840,635) | 3.44 | 113.44 (113.07–113.81) | 4670 (854,660) | 5.46 (5.38–5.54) | 280 (855,109) | 0.33 (0.31–0.35) | 1080 (855,132) | 1.26 (1.22–1.30) | |
Unknown | 9325 | 116 (67–164) | 44 | 20 | 11 | 25 | 280 (2929) | 3.85 | 96.27 (90.7–102.17) | 15 (2969) | 4.71 (3.61–6.16) | REDACTED | REDACTED | REDACTED | REDACTED | |
Asplenia | 108,350 | 170 (154–186) | 40 | 19 | 11 | 30 | 4890 (48,994) | 2.62 | 99.79 (98.37–101.22) | 280 (49,718) | 5.59 (5.27–5.94) | 15 (49744) | 0.32 (0.25–0.41) | 55 (49,746) | 1.13 (0.98–1.29) | |
Asthma | 2,336,650 | 151 (110–178) | 42 | 20 | 11 | 27 | 105,015 (893,242) | 3.43 | 117.57 (117.21–117.93) | 5900 (908,166) | 6.5 (6.41–6.58) | 425 (908,684) | 0.47 (0.44–0.49) | 1070 (908,724) | 1.18 (1.14–1.21) | |
Blood pressure | Normal | 3,190,995 | 137 (87–171) | 41 | 20 | 11 | 28 | 136,085 (1,113,098) | 3.44 | 122.26 (121.93–122.59) | 4975 (1,132,373) | 4.4 (4.33–4.46) | 260 (1,132,792) | 0.23 (0.22–0.24) | 1185 (1,132,816) | 1.05 (1.02–1.08) |
Elevated/high | 3,428,615 | 151 (122–179) | 46 | 19 | 10 | 25 | 136,200 (1,347,493) | 3.08 | 101.08 (100.8–101.35) | 6565 (1,366,494) | 4.8 (4.74–4.86) | 480 (1,367,064) | 0.35 (0.34–0.37) | 1420 (1,367,106) | 1.04 (1.01–1.07) | |
Unknown | 8,881,945 | 152 (113–181) | 48 | 19 | 10 | 24 | 307,500 (3,451,907) | 3.09 | 89.08 (88.92–89.24) | 17,040 (3,494,668) | 4.88 (4.84–4.91) | 1250 (3,496,150) | 0.36 (0.35–0.37) | 3830 (3,496,255) | 1.10 (1.08–1.11) | |
Cancer (non-haematological) | 891,935 | 180 (160–194) | 45 | 17 | 9 | 28 | 25,625 (426,015) | 2.08 | 60.15 (59.77–60.52) | 4065 (429,286) | 9.47 (9.32–9.62) | 235 (429,659) | 0.54 (0.51–0.58) | 1305 (429,678) | 3.04 (2.96–3.13) | |
Chronic kidney disease | Stage 3a | 529,000 | 187 (173–201) | 53 | 16 | 8 | 23 | 12,170 (268,808) | 2.18 | 45.27 (44.87–45.69) | 3370 (270,184) | 12.48 (12.27–12.7) | 190 (270,500) | 0.70 (0.65–0.75) | 1080 (270,514) | 4.00 (3.88–4.12) |
Stage 3b | 206,450 | 192 (178–205) | 52 | 14 | 7 | 27 | 4450 (107,113) | 2.16 | 41.56 (40.95–42.19) | 2105 (107,527) | 19.59 (19.16–20.02) | 95 (107,716) | 0.89 (0.80–0.99) | 795 (107,722) | 7.39 (7.13–7.66) | |
Stage 4 | 51,210 | 191 (174–204) | 47 | 13 | 8 | 33 | 1280 (25,907) | 2.19 | 49.41 (48.05–50.81) | 780 (26,000) | 29.92 (28.87–31.01) | 45 (26,064) | 1.80 (1.56–2.09) | 335 (26067) | 12.85 (12.17–13.57) | |
Stage 5 | 5505 | 184 (164–200) | 29 | 12 | 7 | 52 | 215 (2607) | 1.75 | 82.47 (77.04–88.29) | 130 (2627) | 49.49 (45.33–54.02) | 15 (2638) | 5.31 (4.06–6.93) | 45 (2638) | 17.81 (15.4–20.61) | |
Diabetes | 1,476,880 | 173 (157–191) | 50 | 17 | 9 | 24 | 52,540 (683,694) | 2.80 | 76.85 (76.51–77.18) | 8645 (690,614) | 12.52 (12.39–12.65) | 740 (691,375) | 1.07 (1.03–1.11) | 2255 (691,436) | 3.26 (3.19–3.33) | |
Dialysis | Previous kidney transplant | 2345 | 183 (172–198) | 25 | 15 | 9 | 51 | 155 (1143) | 2.54 | 134.75 (124.32–146.06) | 80 (1159) | 70.73 (63.34–78.99) | 25 (1165) | 19.74 (16.03–24.32) | 30 (1167) | 25.71 (21.42–30.86) |
No previous kidney transplant | 10,505 | 180 (165–199) | 22 | 9 | 7 | 63 | 535 (4982) | 1.38 | 107.19 (102.65–111.93) | 230 (5048) | 45.36 (42.46–48.46) | 25 (5068) | 5.33 (4.40–6.46) | 65 (5070) | 13.22 (11.7–14.93) | |
Heart disease | 1,745,845 | 180 (163–194) | 48 | 17 | 9 | 26 | 51,745 (844,423) | 2.38 | 61.28 (61.01–61.55) | 10,590 (850,928) | 12.45 (12.33–12.57) | 650 (851,904) | 0.76 (0.73–0.79) | 3405 (851,951) | 4.00 (3.93–4.07) | |
Haematological malignancy | 103,625 | 180 (166–193) | 42 | 17 | 9 | 31 | 3725 (49,945) | 2.91 | 74.56 (73.35–75.79) | 1225 (50,386) | 24.35 (23.67–25.06) | 140 (50,481) | 2.79 (2.57–3.04) | 435 (50,492) | 8.62 (8.21–9.04) | |
Immunocompromised | 508,930 | 177 (159–191) | 42 | 18 | 10 | 30 | 21,695 (237,016) | 2.90 | 91.53 (90.91–92.15) | 3950 (240,002) | 16.45 (16.19–16.71) | 450 (240,303) | 1.88 (1.79–1.97) | 1220 (240,339) | 5.08 (4.94–5.23) | |
Learning disability | 102,730 | 160 (146–177) | 47 | 13 | 6 | 33 | 3230 (43,892) | 1.78 | 73.57 (72.28–74.87) | 315 (44,339) | 7.06 (6.67–7.47) | 30 (44,367) | 0.65 (0.54–0.79) | 50 (44371) | 1.13 (0.98–1.30) | |
Liver disease | 348,855 | 164 (144–182) | 45 | 19 | 10 | 26 | 14,020 (151,587) | 2.96 | 92.5 (91.72–93.29) | 1620 (153,529) | 10.55 (10.29–10.81) | 130 (153,667) | 0.85 (0.78–0.93) | 360 (153,678) | 2.36 (2.23–2.48) | |
Neurological disease | 874,635 | 176 (156–193) | 45 | 16 | 8 | 30 | 28,410 (407,866) | 2.29 | 69.66 (69.24–70.07) | 5075 (411,606) | 12.33 (12.16–12.51) | 245 (412,073) | 0.59 (0.55–0.63) | 1685 (412,095) | 4.09 (3.99–4.19) | |
Respiratory disease | 581,930 | 180 (166–193) | 50 | 17 | 9 | 25 | 16,785 (282,315) | 2.53 | 59.45 (58.99–59.91) | 4900 (284,321) | 17.24 (16.99–17.49) | 305 (284,751) | 1.07 (1.01–1.14) | 1515 (284,773) | 5.32 (5.19–5.46) | |
Severe mental illness | 181,865 | 159 (141–177) | 51 | 15 | 8 | 26 | 5135 (76,184) | 2.44 | 67.42 (66.48–68.36) | 650 (76,905) | 8.44 (8.11–8.78) | 50 (76,961) | 0.64 (0.55–0.73) | 155 (76,967) | 2.01 (1.86–2.18) | |
Transplant | Kidney (with previous dialysis) | 5745 | 179 (172–191) | 35 | 18 | 11 | 37 | 395 (2745) | 4.83 | 143.51 (136.46–150.93) | 210 (2787) | 76.08 (71.03–81.49) | 50 (2800) | 17.86 (15.5–20.57) | 55 (2804) | 18.9 (16.47–21.68) |
Kidney (without previous dialysis) | 4515 | 179 (171–191) | 36 | 19 | 11 | 35 | 280 (2160) | 4.65 | 130.07 (122.54–138.06) | 130 (2192) | 58.4 (53.46–63.8) | 25 (2202) | 10.45 (8.48–12.87) | 30 (2203) | 14.52 (12.17–17.33) | |
Other organ | 6780 | 178 (170–188) | 35 | 18 | 11 | 36 | 405 (3202) | 3.91 | 127.12 (120.97–133.58) | 165 (3247) | 50.2 (46.42–54.29) | 40 (3259) | 11.66 (9.91–13.71) | 55 (3262) | 16.86 (14.73–19.29) | |
Time since being fully vaccinated | 0–4 weeks | 331,535 | 16 (8–23) | 63 | 19 | 7 | 11 | 1100 (13,569) | 5.91 | 81.14 (78.73–83.62) | 170 (13,580) | 12.37 (11.45–13.36) | REDACTED | REDACTED | 80 (13,582) | 5.74 (5.13–6.43) |
4–8 weeks | 886,870 | 44 (37–51) | 59 | 20 | 9 | 12 | 5135 (105,598) | 7.09 | 48.65 (47.97–49.33) | 335 (105,819) | 3.15 (2.98–3.32) | 20 (105,825) | 0.18 (0.14–0.23) | 125 (105,826) | 1.17 (1.07–1.28) | |
8–12 weeks | 1,430,095 | 69 (62–76) | 50 | 22 | 11 | 17 | 19,585 (270,294) | 6.32 | 72.45 (71.94–72.97) | 610 (271,783) | 2.25 (2.16–2.34) | 55 (271,801) | 0.20 (0.18–0.23) | 270 (271,804) | 0.99 (0.93–1.05) | |
12+ weeks | 12,853,055 | 159 (135–184) | 44 | 19 | 10 | 27 | 553,960 (5,523,038) | 2.92 | 100.3 (100.16–100.43) | 27,470 (5,602,353) | 4.90 (4.87–4.93) | 1910 (5,604,799) | 0.34 (0.33–0.35) | 5965 (5,604,967) | 1.06 (1.05–1.08) | |
Time between vaccinations | 6 weeks or less | 499,185 | 185 (111–283) | 39 | 18 | 11 | 31 | 17,760 (253,744) | 2.43 | 69.99 (69.47–70.52) | 1630 (256,550) | 6.35 (6.20–6.51) | 85 (256,777) | 0.34 (0.03–0.38) | 450 (256,788) | 1.75 (1.67–1.83) |
6–12 weeks | 13,565,570 | 150 (108–179) | 46 | 19 | 10 | 25 | 519,470 (5,161,343) | 3.20 | 100.65 (100.51–100.79) | 23,120 (5,233,675) | 4.42 (4.39–4.45) | 1635 (5,235,630) | 0.31 (0.03–0.32) | 5005 (5,235,771) | 0.96 (0.94–0.97) | |
12 weeks or more | 1,436,800 | 143 (100–170) | 53 | 18 | 8 | 21 | 42,550 (497,411) | 3.19 | 85.54 (85.13–85.96) | 3830 (503,309) | 7.61 (7.49–7.73) | 270 (503,599) | 0.53 (0.05–0.57) | 980 (503,619) | 1.95 (1.89–2.01) | |
Prior COVID-19 | Between 1st and 2nd vaccination | 191,320 | 65 (42–166) | 48 | 19 | 9 | 24 | 1720 (49,491) | 1.14 | 34.75 (33.93–35.6) | 160 (49,786) | 3.25 (3.01–3.52) | REDACTED | REDACTED | 55 (49,815) | 1.08 (0.95–1.24) |
Before 1st vaccination | 926,960 | 138 (88–170) | 42 | 19 | 10 | 29 | 8895 (326,947) | 1.19 | 27.21 (26.92–27.5) | 755 (328,374) | 2.31 (2.22–2.39) | 30 (328,454) | 0.09 (0.08–0.11) | 200 (328,458) | 0.61 (0.57-0.66) |