09.12.2020 | COVID-19 | original article Open Access
6-month SARS-CoV-2 antibody persistency in a Tyrolian COVID-19 cohort
- Zeitschrift:
- Wiener klinische Wochenschrift
Publisher’s Note
Introduction
Methods
Study population
Case definitions
-
Possible case: any person meeting the clinical criteria
-
Probable case: any person meeting the clinical criteria with an epidemiological link
-
Confirmed case: any person meeting the laboratory criteria.
Samples
Prospective cohort
Assays
Detection of SARS-CoV-2 RNA by real-time PCR
Anti-SARS-CoV-2 binding antibodies (ELISA)
Anti-SARS-CoV-2 neutralizing antibody assay
Statistics
Ethics
Results
Epidemiology
Infection rates in grammar school
Households and partnerships
Antibody positive (
n = 29)
|
Antibody negative (
n = 46)
|
|
---|---|---|
Female/male
|
14/15
|
28/18
|
Age (years, mean
±
SD)
|
44 ± 13.2
|
39 ± 16.8
|
Cases by classification
|
||
Confirmed (
n)
|
13
|
0
|
Probable (
n)
|
15
|
8
|
Asymptomatic (
n)
|
1
|
38
|
SARS-CoV-2 binding antibody assay performance
S1 IgG
|
||||
---|---|---|---|---|
Pos
|
Neg
|
Total
|
||
RBD pan-Ig
|
Pos
|
99
|
3
|
102
|
Neg
|
1
|
64
|
65
|
|
Total
|
100
|
67
|
167
|