Background
Methods
Results
Overall | SARS-COV-2 reinfection | p | |||||
---|---|---|---|---|---|---|---|
No | Yes | ||||||
n = 99,993 | n = 99,783 | n = 210 | |||||
Gender | |||||||
Female | 50,916 | (50.9) | 50,805 | (50.9) | 111 | (52.9) | 0.574 |
Male | 49,077 | (49.1) | 48,978 | (49.1) | 99 | (47.1) | |
Age (mean ± SD, years) | 42.2 ± 13.1 | 42.2 ± 13.1 | 39.2 ± 10.4 | < 0.001 | |||
Age group (years) | |||||||
20–49 | 73,069 | (73.1) | 72,888 | (73.1) | 181 | (86.2) | < 0.001 |
50–59 | 16,755 | (16.8) | 16,735 | (16.7) | 20 | (9.5) | |
60–69 | 6644 | (6.6) | 6638 | (6.7) | 6 | (2.9) | |
70 + | 3525 | (3.5) | 3522 | (3.5) | 3 | (1.4) | |
Occupation | |||||||
Housewife | 10,685 | (10.7) | 10,679 | (10.7) | 6 | (2.9) | < 0.001 |
Healthcare worker | 10,183 | (10.2) | 10,151 | (10.2) | 32 | (15.2) | |
Other healthcare-related | 22,303 | (22.3) | 22,195 | (22.2) | 108 | (51.4) | |
Student | 919 | (0.9) | 919 | (0.9) | 0 | (0) | |
Other | 55,903 | (55.9) | 55,839 | (56.0) | 64 | (30.5) | |
Disease severity (at primary infection) a | |||||||
Mild-moderate | 81,018 | (81.0) | 80,827 | (81.0) | 191 | (91.0) | < 0.001 |
Severe | 18,975 | (19.0) | 18,956 | (19.0) | 19 | (9.0) | |
Personal history of: | |||||||
Obesity (BMI 30 or higher) | |||||||
No | 81,531 | (81.5) | 81,353 | (81.5) | 178 | (84.8) | 0.228 |
Yes | 18,462 | (18.5) | 18,430 | (18.5) | 32 | (15.2) | |
Type 2 diabetes mellitus | |||||||
No | 86,909 | (86.9) | 86,718 | (86.9) | 191 | (91.0) | 0.082 |
Yes | 13,084 | (13.1) | 13,065 | (13.1) | 19 | (9.0) | |
Arterial hypertension | |||||||
No | 82,167 | (82.2) | 81,991 | (82.2) | 176 | (83.8) | 0.535 |
Yes | 17,826 | (17.8) | 17,792 | (17.8) | 34 | (16.2) | |
Immunosuppressionb | |||||||
No | 98,830 | (98.8) | 98,627 | (98.8) | 203 | (96.7) | 0.003 |
Yes | 1163 | (1.2) | 1156 | (1.2) | 7 | (3.3) | |
Chronic kidney disease | |||||||
No | 98,440 | (98.5) | 98,239 | (98.5) | 201 | (95.7) | 0.001 |
Yes | 1553 | (1.5) | 1544 | (1.5) | 9 | (4.3) | |
Chronic obstructive pulmonary disease | |||||||
No | 98,872 | (98.9) | 98,667 | (98.9) | 205 | (97.6) | 0.083 |
Yes | 1121 | (1.1) | 1116 | (1.1) | 5 | (2.4) | |
Asthma | |||||||
No | 96,906 | (96.9) | 96,705 | (96.9) | 201 | (95.7) | 0.315 |
Yes | 3087 | (3.1) | 3078 | (3.1) | 9 | (4.3) | |
Cancer (any site) | |||||||
No | 99,744 | (99.7) | 99,535 | (99.7) | 209 | (99.5) | 0.508 |
Yes | 249 | (0.3) | 248 | (0.3) | 1 | (0.5) |
RR (95% CI), p | ||||||
---|---|---|---|---|---|---|
Bivariate analysis | Multiple analysis | |||||
Gender | ||||||
Female | 1.0000 | 1.0000 | ||||
Male | 0.9998 | (0.9993–1.0004) | 0.574 | 1.0004 | (0.9997–1.0009) | 0.256 |
Age group (years) | ||||||
20–49 | 1.0000 | 1.0000 | ||||
50–59 | 0.9987 | (0.9980–0.9995) | 0.001 | 0.9989 | (0.9981–0.9997) | 0.006 |
60–69 | 0.9984 | (0.9973–0.9996) | 0.007 | 0.9984 | (0.9972–0.9996) | 0.009 |
70 + | 0.9983 | (0.9968–0.9999) | 0.039 | 0.9982 | (0.9966–0.9999) | 0.032 |
Occupation | ||||||
Housewife | 1.0000 | 1.0000 | ||||
Healthcare worker | 1.0043 | (1.0032–1.0054) | < 0.001 | 1.0042 | (1.0030–1.0055) | < 0.001 |
Other healthcare-related | 1.0026 | (1.0013–1.0038) | < 0.001 | 1.0025 | (1.0012–1.0039) | < 0.001 |
Student | 0.9994 | (0.9964–1.0025) | 0.721 | 0.9993 | (0.9961–1.0024) | 0.646 |
Other | 1.0006 | (0.9996–1.0015) | 0.227 | 1.0005 | (0.9994–1.0016) | 0.337 |
Disease severity (at primary infection)a | ||||||
Mild-moderate | 1.0000 | 1.0000 | ||||
Severe | 0.9987 | (0.9979–0.9994) | < 0.001 | 0.9989 | (0.9981–0.9997) | 0.007 |
Personal history of: | ||||||
Obesity (BMI 30 or higher) | ||||||
No | 1.0000 | 1.0000 | ||||
Yes | 0.9996 | (0.9988–1.0003) | 0.228 | 0.9997 | (0.9989–1.0004) | 0.360 |
Type 2 diabetes mellitus | ||||||
No | 1.0000 | 1.0000 | ||||
Yes | 0.9993 | (0.9984–1.0001) | 0.082 | 0.9996 | (0.9987–1.0005) | 0.333 |
Immunosuppressionb | ||||||
No | 1.0000 | 1.0000 | ||||
Yes | 1.0040 | (1.0013–1.0066) | 0.003 | 1.0038 | (1.0011–1.0065) | 0.005 |
Chronic kidney disease | ||||||
No | 1.0000 | 1.0000 | ||||
Yes | 1.0038 | (1.0015–1.0061) | 0.001 | 1.0039 | (1.0016–1.0063) | 0.001 |