nach oben

European Journal of Clinical Microbiology & Infectious Diseases

Erschienen in:

20.10.2020 | COVID-19 | Brief Report Zur Zeit gratis

Evaluation of three immunochromatographic tests in COVID-19 serologic diagnosis and their clinical usefulness

verfasst von: Manuela Pegoraro, Valentina Militello, Gian Luca Salvagno, Stefania Gaino, Antonella Bassi, Cecilia Caloi, Angelo Peretti, Silvia Bizzego, Laura Poletto, Chiara Bovo, Giuseppe Lippi, Giuliana Lo Cascio

Erschienen in: European Journal of Clinical Microbiology & Infectious Diseases | Ausgabe 4/2021

Einloggen, um Zugang zu erhalten

Abstract

Results of three rapid immunochromatographic tests (ICTs) were compared with those obtained with two automated immunoassays for evaluation of their usefulness. One hundred fifty-nine patients and 67 healthy volunteers were included. Different assays demonstrate 41–45% of diagnostic sensitivities and 91–98% of specificities, with substantial agreement (89.3–91.2%), but a high percentage of weak positive results (13–22%) was observed with ICTs. ICTs performances were comparable to those of automated immunoassays. ICTs could have a role as screening approach due to their easy usability. Subjective interpretation, significant rate of uncertain results, uncertainty on viral antigens source are undoubtedly drawbacks.

Callaway E (2020) Time to use the p-word? Coronavirus enter dangerous new phase. Nature 579:12CrossRef

Okba NMA, Muller MA, Li W, Wang C, GeurtsvanKessel CH, Corman VM et al (2020) SARS-CoV-2 specific antibody responses in COVID-19 patients. MedRxiv. https://doi.org/10.1101/2020.03.18.20038059

World Health Organization (2020) Advice on the use of point-of-care immunodiagnostic tests for COVID-19. Sci Brief

World Health Organization (2020) Laboratory testing for coronavirus disease 2019 (COVID-19) in suspected cases. Interim Guid

Li Y, Yao L, Li J, Chen L, Song Y, Cai Z et al (2020) Stability issues of RT-PCR testing of SARS-CoV-2 for hospitalized patients clinically diagnosed with COVID-19. J Med Virol:1–6

Pan Y, Li X, Yang G, Fan J, Tang Y, Zhao J et al (2020) Serological immunocromatographic approach in diagnosis with SARS-CoV-2 infected patients. J Infect 2:54

Lippi G, Salvagno GL, Pegoraro M, Militello V, Caloi C, Peretti A et al (2020) Assessment of antibodies to SARS-CoV2 with the fully automated MAGLUMI 2019-nCoV IgG and IgM chemiluminescence immunoassays. Letter to Editor. Clin Chem Lab Med

Zhao J, Yuan Q, Wang H, Liu W, Liao X, Su Y et al (2020) Antibody responses to SARS-CoV-2 in patients of novel coronavirus disease 2019. Clin Infect Dis

Infantino M, Damiani A, Li Gobbi F, Grossi V, Lari B, Macchia D et al (2020) Serologica assays for SARS-CoV-2 infectious disease: benefits, limitations andpPerspectives. Isr Med Assoc J 22(4):203–210PubMed

10.

Cassaniti I, Novazzi F, Giardina F, Salinaro F, Sachs M, Perlini S et al (2020) Performance of VivaDiag COVID-19 IgM/IgG rapid Ttest is inadequate for diagnosis of COVID-19 in acute patients referring to emergency room department. Letter to Editor. J Med Virol:1–4

Titel: Evaluation of three immunochromatographic tests in COVID-19 serologic diagnosis and their clinical usefulness
verfasst von: Manuela Pegoraro
Valentina Militello
Gian Luca Salvagno
Stefania Gaino
Antonella Bassi
Cecilia Caloi
Angelo Peretti
Silvia Bizzego
Laura Poletto
Chiara Bovo
Giuseppe Lippi
Giuliana Lo Cascio
Publikationsdatum: 20.10.2020
Verlag: Springer Berlin Heidelberg
Schlagwort: COVID-19
Erschienen in: European Journal of Clinical Microbiology & Infectious Diseases / Ausgabe 4/2021
Print ISSN: 0934-9723
Elektronische ISSN: 1435-4373
DOI: https://doi.org/10.1007/s10096-020-04040-1

Leitlinien kompakt für die Innere Medizin

Mit medbee Pocketcards sicher entscheiden.

^{Seit 2022 gehört die medbee GmbH zum Springer Medizin Verlag}

Kostenlos registrieren

Neu im Fachgebiet Innere Medizin

25.04.2024 | Hypotonie | Nachrichten

Update Innere Medizin

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.

Newsletter bestellen

Springer Medizin

Evaluation of three immunochromatographic tests in COVID-19 serologic diagnosis and their clinical usefulness

Abstract

Leitlinien kompakt für die Innere Medizin

Neu im Fachgebiet Innere Medizin

Niedriger diastolischer Blutdruck erhöht Risiko für schwere kardiovaskuläre Komplikationen

Therapiestart mit Blutdrucksenkern erhöht Frakturrisiko

Adjuvante Immuntherapie verlängert Leben bei RCC

Alectinib verbessert krankheitsfreies Überleben bei ALK-positivem NSCLC

Update Innere Medizin

Springer Medizin

Abstract

Bitte loggen Sie sich ein, um Zugang zu diesem Inhalt zu erhalten

Weitere Artikel der Ausgabe 4/2021

Prevalence of hyposmia and hypogeusia in 390 COVID-19 hospitalized patients and outpatients: a cross-sectional study

Description of an influenza outbreak in a French university hospital and risk factors of nosocomial influenza

Bloodstream infection due to Herbaspirillum sp.: case series and review of literature

Prediction of antimicrobial resistance in clinical Campylobacter jejuni isolates from whole-genome sequencing data

Drug screening and development from the affinity of S protein of new coronavirus with ACE2

Prevalence of genital HPV infection in STI and healthy populations and risk factors for viral persistence

Leitlinien kompakt für die Innere Medizin

Neu im Fachgebiet Innere Medizin

Niedriger diastolischer Blutdruck erhöht Risiko für schwere kardiovaskuläre Komplikationen

Therapiestart mit Blutdrucksenkern erhöht Frakturrisiko

Adjuvante Immuntherapie verlängert Leben bei RCC

Alectinib verbessert krankheitsfreies Überleben bei ALK-positivem NSCLC

Update Innere Medizin