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Intensive Care Medicine

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09.06.2020 | COVID-19 | Editorial Zur Zeit gratis

How likely are COVID-19 interventions to benefit the sickest patients?

verfasst von: Anders Perner, Bharath Kumar Tirupakuzhi Vijayaraghavan, Balasubramanian Venkatesh

Erschienen in: Intensive Care Medicine | Ausgabe 7/2020

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Excerpt

The coronavirus disease 2019 (COVID-19) pandemic, caused by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has resulted in more than 4.3 M infections and 297,000 deaths worldwide [1]. It has placed an unprecedented demand on healthcare and overwhelmed the capacity of critical care services in some countries. The manifestations of COVID-19 vary from fever and mild upper respiratory tract symptoms to pneumonia, acute respiratory distress syndrome (ARDS), and multiple organ failure resulting in death [2]. Worsening disease may be driven by increased viral load and hyper-inflammation in addition to increasing age and co-morbidities [2]. Capitalising on this knowledge, several trials are underway testing the efficacy of anti-viral agents, anti-malarial agents, immune modulators, and angiotensin receptor blockers. …

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Titel: How likely are COVID-19 interventions to benefit the sickest patients?
verfasst von: Anders Perner
Bharath Kumar Tirupakuzhi Vijayaraghavan
Balasubramanian Venkatesh
Publikationsdatum: 09.06.2020
Verlag: Springer Berlin Heidelberg
Schlagwort: COVID-19
Erschienen in: Intensive Care Medicine / Ausgabe 7/2020
Print ISSN: 0342-4642
Elektronische ISSN: 1432-1238
DOI: https://doi.org/10.1007/s00134-020-06131-1

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