Background
Methods
Study setting and design
Participants and eligibility criteria
Sample size determination
Operational definitions and variables in the study
SARS-COV-2 assaying procedures using RT-PCR
Data collection method and produces
Statistical analysis
Ethics approval and consent to participate
Results
Socio-demographic and behavioral characteristics
Variables | Frequency (%) |
---|---|
Sex | |
Male | 219 (61.69) |
Female | 136 (38.31) |
Age group | |
1–60 | 279 (78.59) |
> 60 | 76 (21.41) |
Ethnicity | |
Harari | 206 (58.03) |
Oromo | 140 (39.44) |
Other | 9 (2.51) |
Marital status | |
Single | 41 (11.55) |
Married | 303 (85.35) |
Divorced | 4 (1.13) |
Widowed | 7 (1.97) |
Occupational status | |
Employed | 214 (60.28) |
Unemployed | 141 (39.72) |
Smoking status | |
Yes | 143 (40.28) |
No | 212 (59.72) |
Alcohol drinking status | |
Yes | 93 (26.20) |
No | 262 (73.80) |
Presence of comorbidities and clinical findings
Variables | Frequency (%) |
---|---|
COVI-19 clinical stage | |
Critical | 86 (24.29) |
Not critical | 268 (75.71) |
Medication history | |
Yes | 173 (48.73) |
No | 182 (51.27) |
Cough | |
Yes | 279 (78.59) |
No | 76 (21.41) |
Fever | |
Yes | 258 (72.68) |
No | 97 (27.32) |
Shortness of breath | |
Yes | 112 (31.55) |
No | 243 (68.45) |
Hypertensive | |
Yes | 83 (23.38) |
No | 272 (76.62) |
Diabetic | |
Yes | 92 (25.92) |
No | 263 (74.08) |
Cardio vascular disease | |
Yes | 68 (19.15) |
No | 287 (80.85) |
Renal disease | |
Yes | 24 (6.76) |
No | 331 (93.24) |
Receiving dexamethasone | |
Yes | 64 (18.03) |
No | 291 (81.97) |
Covid-19 outcome | |
Discharged | 259 (72.96) |
Death | 96 (27.04) |
Partial oxygen saturation(mmHg) | 81.10 (SD ± 16.63) |
Respiratory rate (breath/minute) | 31.41 (SD ± 10.29) |
Heart rate (bpm) | 100.52 (SD ± 20.31) |
Serum creatinine (mmol/L) | 1.32 (SD ± 1.46) |
Lymphocyte count (1000/µL) | 18.05 (SD ± 14.27) |
Incidence and predictors of organ failure
Variables | Organ failure | COR (95% CI) | AOR with 95% CI | |
---|---|---|---|---|
Yes | No | |||
Age category | ||||
18–60 | 34 | 245 | 1 | 1 |
> 60 | 18 | 58 | 18.55 [9.05, 38.01] | 1.71 [1.44, 4.53]* |
Smoking status | ||||
Yes | 40 | 103 | 6.47 [3.25, 12.87] | 5.07 [1.39, 8.15]* |
No | 12 | 200 | 1 | 1 |
Alcohol utilization | ||||
Yes | 24 | 69 | 2.90 [1.58, 5.33] | 0.89 [0.35, 2.27] |
No | 28 | 234 | 1 | 1 |
Renal disease | ||||
Yes | 10 | 14 | 4.91[2.05, 11.77] | 1.56 [0.56, 2.31] |
No | 42 | 289 | 1 | 1 |
Hypertensive | ||||
Yes | 33 | 50 | 8.78 [4.63, 16.68] | 1.76 [0.59, 5.29] |
No | 19 | 253 | 1 | 1 |
Diabetic | ||||
Yes | 20 | 72 | 2.53 [1.33, 4.80] | 0.47 [0.16, 1.38] |
No | 26 | 237 | 1 | 1 |
Cardiovascular disease | ||||
Yes | 30 | 36 | 14.21 [7.06, 28.61] | 5.00 [1.83,11.72]* |
No | 16 | 273 | 1 | 1 |
COVID-19 clinical stage | ||||
Critical | 36 | 50 | 18.57 [8.65, 39.85] | 5.42 [1.47, 14.84]* |
Noncritical | 10 | 258 | 1 | 1 |
Respiratory rate(bpm) | – | – | 1.13 [1.09, 1.17] | 1.04 [0.98, 1.10] |
Heart rate(bpm) | – | – | 1.05 [1.03, 1.07] | 1.03 [0.55, 1.06] |
Partial Oxygen saturation(mmHg) | – | – | 0.94 [0.92, 0.96] | 1.02 [0.98, 1.07] |
Temperature (°C) | – | – | 4.21[2.78, 6.37] | 1.38[0.83, 2.28] |