Skip to main content
Erschienen in: Digestive Diseases and Sciences 6/2022

12.05.2021 | COVID-19 | Original Article Zur Zeit gratis

Inflammatory Bowel Disease and COVID-19 Vaccination: A Patients’ Survey

verfasst von: Bénédicte Caron, Elise Neuville, Laurent Peyrin-Biroulet

Erschienen in: Digestive Diseases and Sciences | Ausgabe 6/2022

Einloggen, um Zugang zu erhalten

Abstract

Background

Vaccination against COVID-19 is a major public health challenge, including the community of patients with inflammatory bowel disease. Vaccination coverage is suboptimal in inflammatory bowel disease population. It is of paramount importance to ensure an effective and rapid vaccination program with the adherence of the largest number of well-informed patients.

Aims

We assessed the acceptance of COVID-19 vaccination among inflammatory bowel disease patients.

Methods

We performed a survey as part of routine practice, between January 8th and February 22nd, 2021. All consecutive adult patients followed at Nancy University Hospital for inflammatory bowel disease were included. Patients completed a self-administered, structured, paper-based questionnaire. Demographic data, medical history, knowledge, and perceptions of COVID-19 vaccination were collected.

Results

Among the 104 patients who responded to the survey, 57 patients (54.8%) had intent to receive the COVID-19 vaccine. Vaccine efficacy, social responsibility, herd immunity, and desire to return to normal life were associated with self-reported willingness to receive a vaccine (20.2%, 20.2%, 11.5%, and 15.4%, respectively). Unknown long-term safety, risk of adverse reaction to vaccine and concern that the vaccine is being developed too quickly were the most commonly reported reasons for non-uptake (27.9%, 15.4%, and 12.5%, respectively).

Conclusion

Half of the patients with inflammatory bowel disease would like to be vaccinated against SARS-CoV-2. This rate is similar to that reported in the French general population. Despite some concerns, patients with inflammatory bowel disease understood the necessity to be vaccinated against COVID-19.
Literatur
1.
Zurück zum Zitat Allocca M, Chaparro M, Gonzalez HA et al. Patients with inflammatory bowel disease are not at increased risk of COVID-19: a large multinational cohort study. J Clin Med 2020;9:3533.CrossRef Allocca M, Chaparro M, Gonzalez HA et al. Patients with inflammatory bowel disease are not at increased risk of COVID-19: a large multinational cohort study. J Clin Med 2020;9:3533.CrossRef
2.
Zurück zum Zitat Magro F, Rahier J-F, Abreu C et al. Inflammatory bowel disease management during the COVID-19 outbreak: the ten do’s and don’ts from the ECCO-COVID taskforce. J Crohns Colitis 2020;14:S798–S806.CrossRef Magro F, Rahier J-F, Abreu C et al. Inflammatory bowel disease management during the COVID-19 outbreak: the ten do’s and don’ts from the ECCO-COVID taskforce. J Crohns Colitis 2020;14:S798–S806.CrossRef
3.
Zurück zum Zitat Allocca M, Fiorino G, Zallot C et al. Incidence and patterns of COVID-19 among inflammatory bowel disease patients from the Nancy and Milan cohorts. Clin Gastroenterol Hepatol 2020;18:2134–2135.CrossRef Allocca M, Fiorino G, Zallot C et al. Incidence and patterns of COVID-19 among inflammatory bowel disease patients from the Nancy and Milan cohorts. Clin Gastroenterol Hepatol 2020;18:2134–2135.CrossRef
5.
Zurück zum Zitat Voysey M, Clemens SAC, Madhi SA et al. Safety and efficacy of the ChAdOx1 nCoV-19 vaccine (AZD1222) against SARS-CoV-2: an interim analysis of four randomised controlled trials in Brazil, South Africa, and the UK. The Lancet 2021;397:99–111.CrossRef Voysey M, Clemens SAC, Madhi SA et al. Safety and efficacy of the ChAdOx1 nCoV-19 vaccine (AZD1222) against SARS-CoV-2: an interim analysis of four randomised controlled trials in Brazil, South Africa, and the UK. The Lancet 2021;397:99–111.CrossRef
9.
Zurück zum Zitat Larson HJ, Jarrett C, Eckersberger E et al. Understanding vaccine hesitancy around vaccines and vaccination from a global perspective: a systematic review of published literature, 2007–2012. Vaccine 2014;32:2150–2159.CrossRef Larson HJ, Jarrett C, Eckersberger E et al. Understanding vaccine hesitancy around vaccines and vaccination from a global perspective: a systematic review of published literature, 2007–2012. Vaccine 2014;32:2150–2159.CrossRef
10.
Zurück zum Zitat Lane S, MacDonald NE, Marti M, Dumolard L. Vaccine hesitancy around the globe: analysis of three years of WHO/UNICEF joint reporting form data-2015–2017. Vaccine 2018;36:3861–3867.CrossRef Lane S, MacDonald NE, Marti M, Dumolard L. Vaccine hesitancy around the globe: analysis of three years of WHO/UNICEF joint reporting form data-2015–2017. Vaccine 2018;36:3861–3867.CrossRef
11.
Zurück zum Zitat Fadda M, Albanese E, Suggs LS. When a COVID-19 vaccine is ready, will we all be ready for it? Int J Public Health 2020;65:711–712.CrossRef Fadda M, Albanese E, Suggs LS. When a COVID-19 vaccine is ready, will we all be ready for it? Int J Public Health 2020;65:711–712.CrossRef
14.
Zurück zum Zitat Lazarus JV, Ratzan SC, Palayew A et al. A global survey of potential acceptance of a COVID-19 vaccine. Nat Med 2021;27:225–228.CrossRef Lazarus JV, Ratzan SC, Palayew A et al. A global survey of potential acceptance of a COVID-19 vaccine. Nat Med 2021;27:225–228.CrossRef
15.
Zurück zum Zitat Reiter PL, Pennell ML, Katz ML. Acceptability of a COVID-19 vaccine among adults in the United States: How many people would get vaccinated? Vaccine 2020;38:6500–6507.CrossRef Reiter PL, Pennell ML, Katz ML. Acceptability of a COVID-19 vaccine among adults in the United States: How many people would get vaccinated? Vaccine 2020;38:6500–6507.CrossRef
16.
Zurück zum Zitat Coenen S, Weyts E, Jorissen C et al. Effects of education and information on vaccination behavior in patients with inflammatory bowel disease. Inflamm Bowel Dis 2017;23:318–324.CrossRef Coenen S, Weyts E, Jorissen C et al. Effects of education and information on vaccination behavior in patients with inflammatory bowel disease. Inflamm Bowel Dis 2017;23:318–324.CrossRef
17.
Zurück zum Zitat Sitte J, Frentiu E, Baumann C et al. Vaccination for influenza and pneumococcus in patients with gastrointestinal cancer or inflammatory bowel disease: a prospective cohort study of methods for improving coverage. Aliment Pharmacol Ther 2019;49:84–90.CrossRef Sitte J, Frentiu E, Baumann C et al. Vaccination for influenza and pneumococcus in patients with gastrointestinal cancer or inflammatory bowel disease: a prospective cohort study of methods for improving coverage. Aliment Pharmacol Ther 2019;49:84–90.CrossRef
Metadaten
Titel
Inflammatory Bowel Disease and COVID-19 Vaccination: A Patients’ Survey
verfasst von
Bénédicte Caron
Elise Neuville
Laurent Peyrin-Biroulet
Publikationsdatum
12.05.2021
Verlag
Springer US
Schlagwort
COVID-19
Erschienen in
Digestive Diseases and Sciences / Ausgabe 6/2022
Print ISSN: 0163-2116
Elektronische ISSN: 1573-2568
DOI
https://doi.org/10.1007/s10620-021-07040-z

Weitere Artikel der Ausgabe 6/2022

Digestive Diseases and Sciences 6/2022 Zur Ausgabe

Leitlinien kompakt für die Innere Medizin

Mit medbee Pocketcards sicher entscheiden.

Seit 2022 gehört die medbee GmbH zum Springer Medizin Verlag

Update Innere Medizin

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.