26.11.2021 | COVID-19 | Original Article
Zur Zeit gratis
Patient-reported outcomes and complications during head and neck cancer radiotherapy before versus during the COVID-19 pandemic
verfasst von:
Sarah Nicole Hamilton, Nicole Chau, Eric Berthelet, Jonn Wu, Eric Tran, Melanie Chevrier, Victoria Lau, Matthew Chan, Kimberly DeVries, Vincent LaPointe, Robert A. Olson
Erschienen in:
Supportive Care in Cancer
|
Ausgabe 3/2022
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Abstract
Purpose
This study compares patient-reported outcomes and treatment-related complications during radiotherapy before (August 2019–January 2020) versus during (March–Sept 2020) the COVID-19 pandemic.
Materials and methods
The MD Anderson Symptom Inventory-head and neck module was used to assess curative intent in H&N cancer patients’ symptoms during radiotherapy.
Results
There were 158 patients in the pre-pandemic cohort and 137 patients in the pandemic cohort. There was no significant difference in enteral feeding requirements between the cohorts (21% versus 30%, p = 0.07). Weight loss was higher during the pandemic (mean − 5.6% versus 6.8%, p = 0.03). On multivariate analysis, treatment during the pandemic was associated with higher symptom scores for coughing/choking while eating (2.7 versus 2.1, p = 0.013).
Conclusions
Complication rates during H&N radiotherapy during the COVID-19 pandemic were similar at our institution relative to the pre-pandemic era, although weight loss was greater and patients reported more severe choking/coughing while eating.