Skip to main content
Erschienen in: Journal of General Internal Medicine 11/2021

25.06.2021 | COVID-19 | Research and Reporting Methods Zur Zeit gratis

Development of the Verbal Autopsy Instrument for COVID-19 (VAIC)

verfasst von: Tony Rosen, MD, MPH, Monika M. Safford, MD, Madeline R. Sterling, MD, MPH, MS, Parag Goyal, MD, MSc, Melissa Patterson, MD, Christina Al Malouf, MD, Mary Ballin, GNP-BC CDE, Tessa Del Carmen, MD, Veronica M. LoFaso, MD, MS, Barrie L. Raik, MD, Ingrid Custodio, RN, Alyssa Elman, MSW, Sunday Clark, ScD, MPH, Mark S. Lachs, MD, MPH

Erschienen in: Journal of General Internal Medicine | Ausgabe 11/2021

Einloggen, um Zugang zu erhalten

Abstract

Background

Improving accuracy of identification of COVID-19-related deaths is essential to public health surveillance and research. The verbal autopsy, an established strategy involving an interview with a decedent’s caregiver or witness using a semi-structured questionnaire, may improve accurate counting of COVID-19-related deaths.

Objective

To develop and pilot-test the Verbal Autopsy Instrument for COVID-19 (VAIC) and a death adjudication protocol using it.

Methods/Key Results

We used a multi-step process to design the VAIC and a protocol for its use. We developed a preliminary version of a verbal autopsy instrument specifically for COVID. We then pilot-tested this instrument by interviewing respondents about the deaths of 15 adults aged ≥65 during the initial COVID-19 surge in New York City. We modified it after the first 5 interviews. We then reviewed the VAIC and clinical information for the 15 deaths and developed a death adjudication process/algorithm to determine whether the underlying cause of death was definitely (40% of these pilot cases), probably (33%), possibly (13%), or unlikely/definitely not (13%) COVID-19-related. We noted differences between the adjudicated cause of death and a death certificate.

Conclusions

The VAIC and a death adjudication protocol using it may improve accuracy in identifying COVID-19-related deaths.
Anhänge
Nur mit Berechtigung zugänglich
Literatur
1.
Zurück zum Zitat Zylke JW, Bauchner H. Mortality and morbidity: The measure of a pandemic. JAMA. 2020;324:458-9.CrossRef Zylke JW, Bauchner H. Mortality and morbidity: The measure of a pandemic. JAMA. 2020;324:458-9.CrossRef
2.
Zurück zum Zitat Schneider EC. Failing the test - the tragic data gap undermining the U.S. pandemic response. New Engl J Med. 2020;383:299-302.CrossRef Schneider EC. Failing the test - the tragic data gap undermining the U.S. pandemic response. New Engl J Med. 2020;383:299-302.CrossRef
3.
Zurück zum Zitat Pillemer K, Subramanian L, Hupert N. The importance of long-term care populations in models of COVID-19. JAMA. 2020;324:25-6.CrossRef Pillemer K, Subramanian L, Hupert N. The importance of long-term care populations in models of COVID-19. JAMA. 2020;324:25-6.CrossRef
4.
Zurück zum Zitat Woolf SH, Chapman DA, Sabo RT, Weinberger DM, Hill L. Excess deaths from COVID-19 and other causes, March-April 2020. JAMA. 2020;324:510-3.CrossRef Woolf SH, Chapman DA, Sabo RT, Weinberger DM, Hill L. Excess deaths from COVID-19 and other causes, March-April 2020. JAMA. 2020;324:510-3.CrossRef
5.
Zurück zum Zitat Gill JR, DeJoseph ME. The importance of proper death certification during the COVID-19 pandemic. JAMA. 2020;324:27-8.CrossRef Gill JR, DeJoseph ME. The importance of proper death certification during the COVID-19 pandemic. JAMA. 2020;324:27-8.CrossRef
6.
Zurück zum Zitat Leitao J, Chandramohan D, Byass P, et al. Revising the WHO verbal autopsy instrument to facilitate routine cause-of-death monitoring. Glob Health Action. 2013;6:21518.CrossRef Leitao J, Chandramohan D, Byass P, et al. Revising the WHO verbal autopsy instrument to facilitate routine cause-of-death monitoring. Glob Health Action. 2013;6:21518.CrossRef
7.
Zurück zum Zitat Fottrell E, Byass P. Verbal autopsy: Methods in transition. Epidemiol Rev. 2010;32:38-55.CrossRef Fottrell E, Byass P. Verbal autopsy: Methods in transition. Epidemiol Rev. 2010;32:38-55.CrossRef
8.
Zurück zum Zitat Naik PR, Moonan PK, Nirgude AS, et al. Use of verbal autopsy to determine underlying cause of death during treatment of multidrug-resistant tuberculosis, India. Emerg Infect Dis. 2018;24:478.CrossRef Naik PR, Moonan PK, Nirgude AS, et al. Use of verbal autopsy to determine underlying cause of death during treatment of multidrug-resistant tuberculosis, India. Emerg Infect Dis. 2018;24:478.CrossRef
9.
Zurück zum Zitat Lopman B, Cook A, Smith J, et al. Verbal autopsy can consistently measure AIDS mortality: A validation study in Tanzania and Zimbabwe. J Epidemiol and Community Health. 2010;64:330.CrossRef Lopman B, Cook A, Smith J, et al. Verbal autopsy can consistently measure AIDS mortality: A validation study in Tanzania and Zimbabwe. J Epidemiol and Community Health. 2010;64:330.CrossRef
11.
Zurück zum Zitat Halanych JH, Shuaib F, Parmar G, et al. Agreement on cause of death between proxies, death certificates, and clinician adjudicators in the Reasons for Geographic and Racial Differences in Stroke (REGARDS) study. Am J Epidemiol. 2011;173:1319-26.CrossRef Halanych JH, Shuaib F, Parmar G, et al. Agreement on cause of death between proxies, death certificates, and clinician adjudicators in the Reasons for Geographic and Racial Differences in Stroke (REGARDS) study. Am J Epidemiol. 2011;173:1319-26.CrossRef
12.
Zurück zum Zitat Olubowale OT, Safford MM, Brown TM, et al. Comparison of expert adjudicated coronary heart disease and cardiovascular disease mortality with the National Death Index: Results from the Reasons for Geographic And Racial Differences in Stroke (REGARDS) study. J Am Heart Assoc. 2017;6(5). Olubowale OT, Safford MM, Brown TM, et al. Comparison of expert adjudicated coronary heart disease and cardiovascular disease mortality with the National Death Index: Results from the Reasons for Geographic And Racial Differences in Stroke (REGARDS) study. J Am Heart Assoc. 2017;6(5).
13.
Zurück zum Zitat Luepker RV, Apple FS, Christenson RH, et al. Case definitions for acute coronary heart disease in epidemiology and clinical research studies: A statement from the AHA Council on Epidemiology and Prevention; AHA Statistics Committee; World Heart Federation Council on Epidemiology and Prevention; the European Society of Cardiology Working Group on Epidemiology and Prevention; Centers for Disease Control and Prevention; and the National Heart, Lung, and Blood Institute. Circulation. 2003;108:2543-9.CrossRef Luepker RV, Apple FS, Christenson RH, et al. Case definitions for acute coronary heart disease in epidemiology and clinical research studies: A statement from the AHA Council on Epidemiology and Prevention; AHA Statistics Committee; World Heart Federation Council on Epidemiology and Prevention; the European Society of Cardiology Working Group on Epidemiology and Prevention; Centers for Disease Control and Prevention; and the National Heart, Lung, and Blood Institute. Circulation. 2003;108:2543-9.CrossRef
14.
Zurück zum Zitat Goyal P, Choi JJ, Pinheiro LC, et al. Clinical characteristics of Covid-19 in New York City. New Engl J Med. 2020;382:2372-4.CrossRef Goyal P, Choi JJ, Pinheiro LC, et al. Clinical characteristics of Covid-19 in New York City. New Engl J Med. 2020;382:2372-4.CrossRef
15.
Zurück zum Zitat Curb JD, McTiernan A, Heckbert SR, et al. Outcomes ascertainment and adjudication methods in the Women's Health Initiative. Ann Epidemiol. 2003;13:S122-8.CrossRef Curb JD, McTiernan A, Heckbert SR, et al. Outcomes ascertainment and adjudication methods in the Women's Health Initiative. Ann Epidemiol. 2003;13:S122-8.CrossRef
17.
Zurück zum Zitat Pritt BS, Hardin NJ, Richmond JA, Shapiro SL. Death certification errors at an academic institution. Arch Pathol Lab Med. 2005;129:1476-9.CrossRef Pritt BS, Hardin NJ, Richmond JA, Shapiro SL. Death certification errors at an academic institution. Arch Pathol Lab Med. 2005;129:1476-9.CrossRef
18.
Zurück zum Zitat Messite J, Stellman SD. Accuracy of death certificate completion: The need for formalized physician training. JAMA. 1996;275:794-6.CrossRef Messite J, Stellman SD. Accuracy of death certificate completion: The need for formalized physician training. JAMA. 1996;275:794-6.CrossRef
19.
Zurück zum Zitat McGivern L, Shulman L, Carney JK, Shapiro S, Bundock E. Death certification errors and the effect on mortality statistics. Public Health Rep. 2017;132:669-75.CrossRef McGivern L, Shulman L, Carney JK, Shapiro S, Bundock E. Death certification errors and the effect on mortality statistics. Public Health Rep. 2017;132:669-75.CrossRef
20.
Zurück zum Zitat National Center for Health Statistics. National Death Index: User's Guide. National Center for Health Statistics. National Death Index: User's Guide.
21.
Zurück zum Zitat Safford MM, Brown TM, Muntner PM, et al. Association of race and sex with risk of incident acute coronary heart disease events. JAMA. 2012;308:1768-74.CrossRef Safford MM, Brown TM, Muntner PM, et al. Association of race and sex with risk of incident acute coronary heart disease events. JAMA. 2012;308:1768-74.CrossRef
22.
Zurück zum Zitat Serina P, Riley I, Hernandez B, et al. What is the optimal recall period for verbal autopsies? Validation study based on repeat interviews in three populations. Popul Health Metr. 2016;14:1-8.CrossRef Serina P, Riley I, Hernandez B, et al. What is the optimal recall period for verbal autopsies? Validation study based on repeat interviews in three populations. Popul Health Metr. 2016;14:1-8.CrossRef
23.
Zurück zum Zitat Egede LE, Walker RJ, Garacci E, Raymond Sr JR. Racial/ethnic differences in COVID-19 screening, hospitalization, and mortality in southeast Wisconsin. Health Aff. 2020;39:1926-34.CrossRef Egede LE, Walker RJ, Garacci E, Raymond Sr JR. Racial/ethnic differences in COVID-19 screening, hospitalization, and mortality in southeast Wisconsin. Health Aff. 2020;39:1926-34.CrossRef
24.
25.
Zurück zum Zitat McCarty TR, Hathorn KE, Redd WD, et al. How do presenting symptoms and outcomes differ by race/ethnicity among hospitalized patients with Coronavirus Disease 2019 Infection? Experience in Massachusetts. Clin Infect Dis. 2020. Aug 22;ciaa1245. doi: https://doi.org/10.1093/cid/ciaa1245. McCarty TR, Hathorn KE, Redd WD, et al. How do presenting symptoms and outcomes differ by race/ethnicity among hospitalized patients with Coronavirus Disease 2019 Infection? Experience in Massachusetts. Clin Infect Dis. 2020. Aug 22;ciaa1245. doi: https://​doi.​org/​10.​1093/​cid/​ciaa1245.
27.
Zurück zum Zitat Stokes EK, Zambrano LD, Anderson KN, et al. Coronavirus Disease 2019 Case Surveillance - United States, January 22-May 30, 2020. MMWR Morb Mortal Wkly Rep. 2020;69:759-65.CrossRef Stokes EK, Zambrano LD, Anderson KN, et al. Coronavirus Disease 2019 Case Surveillance - United States, January 22-May 30, 2020. MMWR Morb Mortal Wkly Rep. 2020;69:759-65.CrossRef
28.
Zurück zum Zitat Eythorsson E, Helgason D, Ingvarsson RF, et al. Clinical spectrum of coronavirus disease 2019 in Iceland: Population based cohort study. BMJ. 2020;371:m4529.CrossRef Eythorsson E, Helgason D, Ingvarsson RF, et al. Clinical spectrum of coronavirus disease 2019 in Iceland: Population based cohort study. BMJ. 2020;371:m4529.CrossRef
29.
Zurück zum Zitat Roland LT, Gurrola JG, Loftus PA, Cheung SW, Chang JL. Smell and taste symptom-based predictive model for COVID-19 diagnosis. Int Forum Allergy Rhinol. 2020 Jul;10(7):832-838.CrossRef Roland LT, Gurrola JG, Loftus PA, Cheung SW, Chang JL. Smell and taste symptom-based predictive model for COVID-19 diagnosis. Int Forum Allergy Rhinol. 2020 Jul;10(7):832-838.CrossRef
Metadaten
Titel
Development of the Verbal Autopsy Instrument for COVID-19 (VAIC)
verfasst von
Tony Rosen, MD, MPH
Monika M. Safford, MD
Madeline R. Sterling, MD, MPH, MS
Parag Goyal, MD, MSc
Melissa Patterson, MD
Christina Al Malouf, MD
Mary Ballin, GNP-BC CDE
Tessa Del Carmen, MD
Veronica M. LoFaso, MD, MS
Barrie L. Raik, MD
Ingrid Custodio, RN
Alyssa Elman, MSW
Sunday Clark, ScD, MPH
Mark S. Lachs, MD, MPH
Publikationsdatum
25.06.2021
Verlag
Springer International Publishing
Schlagwörter
COVID-19
SARS-CoV-2
Erschienen in
Journal of General Internal Medicine / Ausgabe 11/2021
Print ISSN: 0884-8734
Elektronische ISSN: 1525-1497
DOI
https://doi.org/10.1007/s11606-021-06842-1

Weitere Artikel der Ausgabe 11/2021

Journal of General Internal Medicine 11/2021 Zur Ausgabe

Leitlinien kompakt für die Innere Medizin

Mit medbee Pocketcards sicher entscheiden.

Seit 2022 gehört die medbee GmbH zum Springer Medizin Verlag

Update Innere Medizin

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.