The onset of the COVID-19 pandemic generated an unprecedented shift in the delivery of musculoskeletal care. Restricted access to in-person services and concerns about exposure to SARS-CoV-2, the virus that causes COVID-19, contributed to the rapid acceptance of telerehabilitation. This change resulted in distinct challenges for both the patient and the therapist. Homes and apartments were repurposed into examination rooms and therapy gyms. Physical examination and intervention options were limited as hands-on techniques could not be implemented. The constraints of telerehabilitation pushed practitioners to reevaluate their practice patterns and reallocate their time, resources, and focus. Prior to the pandemic, the implementation of telerehabilitation was shown to result in clinically meaningful improvements in pain, disability, and quality of life across a variety of conditions [
2,
3]. This transition fostered a new appreciation for the value of three important aspects of guideline-based care: interpersonal communication, education, and self-management. This commentary highlights our experiences and lessons learned in each of these areas while providing guideline-based telerehabilitation. …