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Zeitschrift

Critical Care

Critical Care 1/2017

Ausgabe 1/2017

Inhaltsverzeichnis ( 317 Artikel )

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Role of vasopressin and terlipressin in refractory shock compared to conventional therapy in the neonatal and pediatric population: a systematic review, meta-analysis, and trial sequential analysis

Reem Masarwa, Gideon Paret, Amichai Perlman, Shimon Reif, Bruria Hirsh Raccah, Ilan Matok

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Is platelet transfusion associated with hospital-acquired infections in critically ill patients?

Cécile Aubron, Andrew W. Flint, Michael Bailey, David Pilcher, Allen C. Cheng, Colin Hegarty, Antony Martinelli, Michael C. Reade, Rinaldo Bellomo, Zoe McQuilten

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Effect of perioperative sodium bicarbonate administration on renal function following cardiac surgery for infective endocarditis: a randomized, placebo-controlled trial

Jin Sun Cho, Sarah Soh, Jae-Kwang Shim, Sanghwa Kang, Haegi Choi, Young-Lan Kwak

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Use of noninvasive ventilation in immunocompromised patients with acute respiratory failure: a systematic review and meta-analysis

Hui-Bin Huang, Biao Xu, Guang-Yun Liu, Jian-Dong Lin, Bin Du

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Normal saline versus heparin for patency of central venous catheters in adult patients - a systematic review and meta-analysis

Lei Zhong, Hai-Li Wang, Bo Xu, Yao Yuan, Xin Wang, Ying-ying Zhang, Li Ji, Zi-mu Pan, Zhan-Sheng Hu

01.12.2017 | Letter | Ausgabe 1/2017 Open Access

Patients want to be heard–loud and clear!

Anna-Liisa Sutt, John F. Fraser

01.12.2017 | Letter | Ausgabe 1/2017 Open Access

Communicating with conscious mechanically ventilated critically ill patients: let them speak with deflated cuff and an in-line speaking valve!

Peter H. Egbers, E. Christiaan Boerma

01.12.2017 | Letter | Ausgabe 1/2017 Open Access

Should we assume that hypothermia is a dysfunction in sepsis?

Alexandre A. Steiner, Monique T. Fonseca, Francisco G. Soriano

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Whole-body vibration to prevent intensive care unit-acquired weakness: safety, feasibility, and metabolic response

Tobias Wollersheim, Kurt Haas, Stefan Wolf, Knut Mai, Claudia Spies, Elisabeth Steinhagen-Thiessen, Klaus-D. Wernecke, Joachim Spranger, Steffen Weber-Carstens

01.12.2017 | Editorial | Ausgabe 1/2017 Open Access

Promoting early identification of sepsis in hospitalized patients with nurse-led protocols

Ruth Kleinpell

01.12.2017 | Editorial | Ausgabe 1/2017 Open Access

Towards precision medicine for sepsis patients

Peter Pickkers, Matthijs Kox

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Does training improve diagnostic accuracy and inter-rater agreement in applying the Berlin radiographic definition of acute respiratory distress syndrome? A multicenter prospective study

Jin-Min Peng, Chuan-Yun Qian, Xiang-You Yu, Ming-Yan Zhao, Shu-Sheng Li, Xiao-Chun Ma, Yan Kang, Fa-Chun Zhou, Zhen-Yang He, Tie-He Qin, Yong-Jie Yin, Li Jiang, Zhen-Jie Hu, Ren-Hua Sun, Jian-Dong Lin, Tong Li, Da-Wei Wu, You-Zhong An, Yu-Hang Ai, Li-Hua Zhou, Xiang-Yuan Cao, Xi-Jing Zhang, Rong-Qing Sun, Er-Zhen Chen, Bin Du, for the China Critical Care Clinical Trial Group (CCCCTG)

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Can calculation of energy expenditure based on CO2 measurements replace indirect calorimetry?

Taku Oshima, Séverine Graf, Claudia-Paula Heidegger, Laurence Genton, Jérôme Pugin, Claude Pichard

01.12.2017 | Research | Ausgabe 1/2017 Open Access

The role of total cell-free DNA in predicting outcomes among trauma patients in the intensive care unit: a systematic review

Mikail Gögenur, Jakob Burcharth, Ismail Gögenur

01.12.2017 | Research | Ausgabe 1/2017 Open Access

The association of findings on brain computed tomography with neurologic outcomes following extracorporeal cardiopulmonary resuscitation

Jeong-Am Ryu, Chi Ryang Chung, Yang Hyun Cho, Kiick Sung, Gee Young Suh, Taek Kyu Park, Young Bin Song, Joo-Yong Hahn, Jin-Ho Choi, Hyeon-Cheol Gwon, Seung-Hyuk Choi, Jeong Hoon Yang

01.12.2017 | Erratum | Ausgabe 1/2017 Open Access

Erratum to: Volume and its relationship to cardiac output and venous return

S. Magder

01.12.2017 | Letter | Ausgabe 1/2017 Open Access

Optimal doses of caspofungin during continuous venovenous hemodiafiltration in critically ill patients

Gerardo Aguilar, Rafael Ferriols, Angels Lozano, Carlos Ezquer, José A. Carbonell, Ana Jurado, Juan Carrizo, Ferran Serralta, Jaume Puig, David Navarro, Manuel Alos, F. Javier Belda

01.12.2017 | Letter | Ausgabe 1/2017 Open Access

Immunotherapy improves the prognosis of lung cancer: do we have to change intensive care unit admission and triage guidelines?

Antoine Guillon, Karen L. Reckamp, Nathalie Heuzé-Vourc’h

01.12.2017 | Editorial | Ausgabe 1/2017 Open Access

Viral and bacterial co-infection in pneumonia: do we know enough to improve clinical care?

Kelly A. Cawcutt, Andre C. Kalil

01.12.2017 | Editorial | Ausgabe 1/2017 Open Access

Predicting critical illness mortality and personalizing therapy: moving to multi-dimensional data

Zudin A. Puthucheary, Paul Wischmeyer

01.12.2017 | Research | Ausgabe 1/2017 Open Access

A diaphragmatic electrical activity-based optimization strategy during pressure support ventilation improves synchronization but does not impact work of breathing

Francois Beloncle, Lise Piquilloud, Nuttapol Rittayamai, Christer Sinderby, Hadrien Rozé, Laurent Brochard

01.12.2017 | Research | Ausgabe 1/2017 Open Access

A randomized placebo-controlled phase II study of a Pseudomonas vaccine in ventilated ICU patients

Jordi Rello, Claus-Georg Krenn, Gottfried Locker, Ernst Pilger, Christian Madl, Laura Balica, Thierry Dugernier, Pierre-Francois Laterre, Herbert Spapen, Pieter Depuydt, Jean-Louis Vincent, Lajos Bogár, Zsuzsanna Szabó, Barbara Völgyes, Rafael Máñez, Nahit Cakar, Atilla Ramazanoglu, Arzu Topeli, Maria A. Mastruzzo, Abel Jasovich, Christian G. Remolif, Liliana del Carmen Soria, Max A. Andresen Hernandez, Carolina Ruiz Balart, Ildikó Krémer, Zsolt Molnár, Frank von Sonnenburg, Arthur Lyons, Michael Joannidis, Heinz Burgmann, Tobias Welte, Anton Klingler, Romana Hochreiter, Kerstin Westritschnig

01.12.2017 | Research | Ausgabe 1/2017 Open Access

The effects of low tidal ventilation on lung strain correlate with respiratory system compliance

Jianfeng Xie, Fang Jin, Chun Pan, Songqiao Liu, Ling Liu, Jingyuan Xu, Yi Yang, Haibo Qiu

01.12.2017 | Letter | Ausgabe 1/2017 Open Access

Skin autofluorescence in acute kidney injury

Aurelie Lavielle, Sebastien Rubin, Alexandre Boyer, Karine Moreau, Kalina Rajaobelina, Christian Combe, Vincent Rigalleau

01.12.2017 | Review | Ausgabe 1/2017 Open Access

Shock induced endotheliopathy (SHINE) in acute critical illness - a unifying pathophysiologic mechanism

PärIngemar Johansson, Jakob Stensballe, SisseRye Ostrowski

01.12.2017 | Editorial | Ausgabe 1/2017 Open Access

Could type 2 diabetes be a component of the post-intensive care syndrome?

Jean-Charles Preiser, Caroline de Longueville

01.12.2017 | Letter | Ausgabe 1/2017 Open Access

Freedom of speech for all critically ill patients: work in progress

P. R. Tuinman, S. ten Hoorn

01.12.2017 | Letter | Ausgabe 1/2017 Open Access

Blood pressure and acute kidney injury

Ryota Sato, Sarah Kyuragi Luthe, Michitaka Nasu

01.12.2017 | Letter | Ausgabe 1/2017 Open Access

The importance of diastolic dysfunction in the development of weaning-induced pulmonary oedema

Filippo Sanfilippo, Cristina Santonocito, Gaetano Burgio, Antonio Arcadipane

01.12.2017 | Letter | Ausgabe 1/2017 Open Access

A response to “Response to a Trial on Reversal of Death by Neurologic Criteria”

Ira S. Pastor

01.12.2017 | Research | Ausgabe 1/2017 Open Access

The success of pre-hospital tracheal intubation by different pre-hospital providers: a systematic literature review and meta-analysis

K. Crewdson, D. J. Lockey, J. Røislien, H. M. Lossius, M. Rehn

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Point-of-care testing for emergency assessment of coagulation in patients treated with direct oral anticoagulants

Matthias Ebner, Ingvild Birschmann, Andreas Peter, Charlotte Spencer, Florian Härtig, Joachim Kuhn, Gunnar Blumenstock, Christine S. Zuern, Ulf Ziemann, Sven Poli

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Use of stepwise lactate kinetics-oriented hemodynamic therapy could improve the clinical outcomes of patients with sepsis-associated hyperlactatemia

Xiang Zhou, Dawei Liu, Longxiang Su, Bo Yao, Yun Long, Xiaoting Wang, Wenzhao Chai, Na Cui, Hao Wang, Xi Rui

01.12.2017 | Research | Ausgabe 1/2017 Open Access

The impact of post-operative sepsis on mortality after hospital discharge among elective surgical patients: a population-based cohort study

Lixin Ou, Jack Chen, Ken Hillman, Arthas Flabouris, Michael Parr, Hassan Assareh, Rinaldo Bellomo

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Noninvasive detection of alarming intracranial pressure changes by auditory monitoring in early management of brain injury: a prospective invasive versus noninvasive study

Fabrice Giraudet, François Longeras, Aurélien Mulliez, Aurélie Thalamy, Bruno Pereira, Paul Avan, Laurent Sakka

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Can body mass index predict clinical outcomes for patients with acute lung injury/acute respiratory distress syndrome? A meta-analysis

Yue-Nan Ni, Jian Luo, He Yu, Yi-Wei Wang, Yue-Hong Hu, Dan Liu, Bin-Miao Liang, Zong-An Liang

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Catecholamines as outcome markers in isolated traumatic brain injury: the COMA-TBI study

Sandro B. Rizoli, Blessing N. R. Jaja, Alex P. Di Battista, Shawn G. Rhind, Antonio Capone Neto, Leodante da Costa, Kenji Inaba, Luis Teodoro da Luz, Bartolomeu Nascimento, Adic Perez, Andrew J. Baker, Airton Leonardo de Oliveira Manoel

01.12.2017 | Research | Ausgabe 1/2017 Open Access

SOFA and mortality endpoints in randomized controlled trials: a systematic review and meta-regression analysis

Harm-Jan de Grooth, Irma L. Geenen, Armand R. Girbes, Jean-Louis Vincent, Jean-Jacques Parienti, Heleen M. Oudemans-van Straaten

01.12.2017 | Letter | Ausgabe 1/2017 Open Access

Optimal energy delivery and measured energy expenditure—impact of length of stay

Mette M. Berger, Claude Pichard, Eric Fontaine

01.12.2017 | Erratum | Ausgabe 1/2017 Open Access

Erratum to: Hemodynamic consequences of severe lactic acidosis in shock states: from bench to bedside

Antoine Kimmoun, Emmanuel Novy, Thomas Auchet, Nicolas Ducrocq, Bruno Levy

01.12.2017 | Erratum | Ausgabe 1/2017 Open Access

Erratum to: Resuscitative endovascular balloon occlusion of the aorta versus aortic cross clamping among patients with critical trauma: a nationwide cohort study in Japan

Toshikazu Abe, Masatoshi Uchida, Isao Nagata, Daizoh Saitoh, Nanako Tamiya

01.12.2017 | Erratum | Ausgabe 1/2017 Open Access

Erratum to: Probiotic and synbiotic therapy in critical illness: a systematic review and meta-analysis

William Manzanares, Paul E. Wischmeyer

01.12.2017 | Letter | Ausgabe 1/2017 Open Access

Response to “Reassessing the death risk related to probiotics in critically ill patients”

William Manzanares, Paul E. Wischmeyer

01.12.2017 | Research | Ausgabe 1/2017 Open Access

The accuracy of transcranial Doppler in excluding intracranial hypertension following acute brain injury: a multicenter prospective pilot study

Frank A. Rasulo, Rita Bertuetti, Chiara Robba, Francesco Lusenti, Alfredo Cantoni, Marta Bernini, Alan Girardini, Stefano Calza, Simone Piva, Nazzareno Fagoni, Nicola Latronico

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Duration of veno-arterial extracorporeal life support (VA ECMO) and outcome: an analysis of the Extracorporeal Life Support Organization (ELSO) registry

Myles Smith, Alexander Vukomanovic, Daniel Brodie, Ravi Thiagarajan, Peter Rycus, Hergen Buscher

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Evaluation of clinically available renal biomarkers in critically ill adults: a prospective multicenter observational study

Yujun Deng, Ruibin Chi, Shenglong Chen, Heng Ye, Jie Yuan, Lin Wang, Yiling Zhai, Lu Gao, Danqing Zhang, Linhui Hu, Bo Lv, Yi Long, Cheng Sun, Xiaobing Yang, Xia Zou, Chunbo Chen

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Genetic variants in SERPINA4 and SERPINA5, but not BCL2 and SIK3 are associated with acute kidney injury in critically ill patients with septic shock

Laura M. Vilander, Mari A. Kaunisto, Suvi T. Vaara, Ville Pettilä, the FINNAKI study group

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Decreased cytokine production by mononuclear cells after severe gram-negative infections: early clinical signs and association with final outcome

Nikolaos Antonakos, Thomas Tsaganos, Volker Oberle, Iraklis Tsangaris, Malvina Lada, Aikaterini Pistiki, Nikolaos Machairas, Maria Souli, Michael Bauer, Evangelos J. Giamarellos-Bourboulis

01.12.2017 | Letter | Ausgabe 1/2017 Open Access

Blood components are essential to regulate microcirculatory blood flow

Nicolas Morel, Marie Moisan

01.12.2017 | Erratum | Ausgabe 1/2017 Open Access

Erratum to: Cardiac dysfunction induced by weaning from mechanical ventilation: incidence, risk factors, and effects of fluid removal

Jinglun Liu, Feng Shen, Jean-Louis Teboul, Nadia Anguel, Alexandra Beurton, Nadia Bezaz, Christian Richard, Xavier Monnet

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Dual inhibition of thrombin and activated factor X attenuates disseminated intravascular coagulation and protects organ function in a baboon model of severe Gram-negative sepsis

Herbert Schöchl, Martijn van Griensven, Stefan Heitmeier, Volker Laux, Ulrike Kipman, Jan Roodt, Soheyl Bahrami, Heinz Redl

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Effect of an automated notification system for deteriorating ward patients on clinical outcomes

Christian P. Subbe, Bernd Duller, Rinaldo Bellomo

01.12.2017 | Letter | Ausgabe 1/2017 Open Access

Assessing preoperative plasma growth-differentiation factor-15 for prediction of acute kidney injury in patients undergoing cardiac surgery

Wei Zhang, Hai Chen Chu, Feng Xue

01.12.2017 | Letter | Ausgabe 1/2017 Open Access

Point-of-care ultrasonography and liberation from mechanical ventilation

Gentle Sunder Shrestha

01.12.2017 | Letter | Ausgabe 1/2017 Open Access

What is the risk of acquiring bacteria from prior intensive care unit bed occupants?

Vincenzo Russotto, Andrea Cortegiani, Santi Maurizio Raineri, Pasquale Iozzo, Cesare Gregoretti, Antonino Giarratano

01.12.2017 | Review | Ausgabe 1/2017 Open Access

Antiarrhythmic drugs for out-of-hospital cardiac arrest with refractory ventricular fibrillation

Takashi Tagami, Hideo Yasunaga, Hiroyuki Yokota

01.12.2017 | Review | Ausgabe 1/2017 Open Access

Use of ‘tidal volume challenge’ to improve the reliability of pulse pressure variation

Sheila Nainan Myatra, Xavier Monnet, Jean-Louis Teboul

01.12.2017 | Review | Ausgabe 1/2017 Open Access

Anemia and blood transfusion in the critically ill patient with cardiovascular disease

Annemarie B. Docherty, Timothy S. Walsh

01.12.2017 | Review | Ausgabe 1/2017 Open Access

High-flow nasal cannula support therapy: new insights and improving performance

Gonzalo Hernández, Oriol Roca, Laura Colinas

01.12.2017 | Review | Ausgabe 1/2017 Open Access

Mechanical ventilation in obese ICU patients: from intubation to extubation

Audrey De Jong, Gerald Chanques, Samir Jaber

01.12.2017 | Review | Ausgabe 1/2017 Open Access

Novel insights in ICU-acquired respiratory muscle dysfunction: implications for clinical care

Annemijn H. Jonkman, Diana Jansen, Leo M. A. Heunks

01.12.2017 | Review | Ausgabe 1/2017 Open Access

Neuroanatomy of sepsis-associated encephalopathy

Nicholas Heming, Aurelien Mazeraud, Franck Verdonk, Fernando A. Bozza, Fabrice Chrétien, Tarek Sharshar

01.12.2017 | Review | Ausgabe 1/2017 Open Access

Medicating patients during extracorporeal membrane oxygenation: the evidence is building

Amy L. Dzierba, Darryl Abrams, Daniel Brodie

01.12.2017 | Review | Ausgabe 1/2017 Open Access

Anti-inflammatory properties of anesthetic agents

Fernanda Ferreira Cruz, Patricia Rieken Macedo Rocco, Paolo Pelosi

01.12.2017 | Review | Ausgabe 1/2017 Open Access

Facing the ongoing challenge of the febrile young infant

Adrienne G. DePorre, Paul L. Aronson, Russell J. McCulloh

01.12.2017 | Research | Ausgabe 1/2017 Open Access

The association of time and medications with changes in bone mineral density in the 2 years after critical illness

Neil R. Orford, Michael Bailey, Rinaldo Bellomo, Julie A. Pasco, Claire Cattigan, Tania Elderkin, Sharon L. Brennan-Olsen, David J. Cooper, Mark A. Kotowicz

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Intestinal T lymphocyte homing is associated with gastric emptying and epithelial barrier function in critically ill: a prospective observational study

Christian Greis, Zohal Rasuly, Rolf A. Janosi, Lambros Kordelas, Dietrich W. Beelen, Tobias Liebregts

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Predictors of hospital and one-year mortality in intensive care patients with refractory status epilepticus: a population-based study

Anne-Mari Kantanen, Reetta Kälviäinen, Ilkka Parviainen, Marika Ala-Peijari, Tom Bäcklund, Juha Koskenkari, Ruut Laitio, Matti Reinikainen

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Time-dependent association of glucocorticoids with adverse outcome in community-acquired pneumonia: a 6-year prospective cohort study

Manuela Nickler, Manuel Ottiger, Christian Steuer, Alexander Kutz, Mirjam Christ-Crain, Werner Zimmerli, Robert Thomann, Claus Hoess, Christoph Henzen, Luca Bernasconi, Andreas Huber, Beat Mueller, Philipp Schuetz, for the ProHOSP Study Group

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Comparison of qSOFA and SIRS for predicting adverse outcomes of patients with suspicion of sepsis outside the intensive care unit

Eli J. Finkelsztein, Daniel S. Jones, Kevin C. Ma, Maria A. Pabón, Tatiana Delgado, Kiichi Nakahira, John E. Arbo, David A. Berlin, Edward J. Schenck, Augustine M. K. Choi, Ilias I. Siempos

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Hemoadsorption by CytoSorb in septic patients: a case series

Klaus Kogelmann, Dominik Jarczak, Morten Scheller, Matthias Drüner

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Clonidine for sedation in the critically ill: a systematic review and meta-analysis

Jing Gennie Wang, Emilie Belley-Coté, Lisa Burry, Mark Duffett, Timothy Karachi, Dan Perri, Waleed Alhazzani, Frederick D’Aragon, Hannah Wunsch, Bram Rochwerg

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Life-threatening massive pulmonary embolism rescued by venoarterial-extracorporeal membrane oxygenation

Fillipo Corsi, Guillaume Lebreton, Nicolas Bréchot, Guillaume Hekimian, Ania Nieszkowska, Jean-Louis Trouillet, Charles-Edouard Luyt, Pascal Leprince, Jean Chastre, Alain Combes, Matthieu Schmidt

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Diagnostic value of urinary tissue inhibitor of metalloproteinase-2 and insulin-like growth factor binding protein 7 for acute kidney injury: a meta-analysis

Hui-Miao Jia, Li-Feng Huang, Yue Zheng, Wen-Xiong Li

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Corticosteroids in septic shock: a systematic review and network meta-analysis

Ben Gibbison, José A. López-López, Julian P. T. Higgins, Tom Miller, Gianni D. Angelini, Stafford L. Lightman, Djillali Annane

01.12.2017 | Review | Ausgabe 1/2017 Open Access

A path to precision in the ICU

David M. Maslove, Francois Lamontagne, John C. Marshall, Daren K. Heyland

01.12.2017 | Letter | Ausgabe 1/2017 Open Access

Anatomic changes after repair of traumatic bilateral diaphragmatic rupture impede bi-caval dual lumen catheter insertion for veno-venous extracorporeal membrane oxygenation treatment

Alexa Hollinger, Daniel Tuchscherer, Jens Bremerich, Martin Siegemund

01.12.2017 | Letter | Ausgabe 1/2017 Open Access

Lice, rodents, and many hopes: a rare disease in a young refugee

Salvatore L. Cutuli, Gennaro De Pascale, Teresa Spanu, Antonio M. Dell’Anna, Maria G. Bocci, Federico Pallavicini, Fabiola Mancini, Alessandra Ciervo, Massimo Antonelli

01.12.2017 | Letter | Ausgabe 1/2017 Open Access

VCO2-derived energy expenditure: do not throw the baby out with the bath water!

Sandra N. Stapel, Paul W. G. Elbers, Heleen M. Oudemans-van Straaten

01.12.2017 | Editorial | Ausgabe 1/2017 Open Access

Inhaled nitric oxide and acute kidney injury: new insights from observational data

Laveena Munshi, Neill K. J. Adhikari

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Implementing a bedside assessment of respiratory mechanics in patients with acute respiratory distress syndrome

Lu Chen, Guang-Qiang Chen, Kevin Shore, Orest Shklar, Concetta Martins, Brian Devenyi, Paul Lindsay, Heather McPhail, Ashley Lanys, Ibrahim Soliman, Mazin Tuma, Michael Kim, Kerri Porretta, Pamela Greco, Hilary Every, Chris Hayes, Andrew Baker, Jan O. Friedrich, Laurent Brochard

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Determinants of the calibration of SAPS II and SAPS 3 mortality scores in intensive care: a European multicenter study

Antoine Poncet, Thomas V. Perneger, Paolo Merlani, Maurizia Capuzzo, Christophe Combescure

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Retinal arterial blood flow and retinal changes in patients with sepsis: preliminary study using fluorescein angiography

Kristo Erikson, Janne Henrik Liisanantti, Nina Hautala, Juha Koskenkari, Remi Kamakura, Karl Heinz Herzig, Hannu Syrjälä, Tero Ilmari Ala-Kokko

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Renal function and oxygenation are impaired early after liver transplantation despite hyperdynamic systemic circulation

Jenny Skytte Larsson, Gudrun Bragadottir, Bengt Redfors, Sven-Erik Ricksten

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Cardiac biomarkers are associated with maximum stage of acute kidney injury in critically ill patients: a prospective analysis

Ryan Haines, Siobhan Crichton, Jessica Wilson, David Treacher, Marlies Ostermann

01.12.2017 | Review | Ausgabe 1/2017 Open Access

New drugs, new toxicities: severe side effects of modern targeted and immunotherapy of cancer and their management

Frank Kroschinsky, Friedrich Stölzel, Simone von Bonin, Gernot Beutel, Matthias Kochanek, Michael Kiehl, Peter Schellongowski, on behalf of the Intensive Care in Hematological and Oncological Patients (iCHOP) Collaborative Group

01.12.2017 | Review | Ausgabe 1/2017 Open Access

Clinical pathophysiology of hypoxic ischemic brain injury after cardiac arrest: a “two-hit” model

Mypinder S. Sekhon, Philip N. Ainslie, Donald E. Griesdale

01.12.2017 | Letter | Ausgabe 1/2017 Open Access

Feasibility and safety of whole-body vibration therapy in intensive care patients

Peter Alter, Tobias Boeselt, Christoph Nell, Marc Spielmanns, Klaus Kenn, A. Rembert Koczulla

01.12.2017 | Review | Ausgabe 1/2017 Open Access

The future of critical care: renal support in 2027

William R. Clark, Mauro Neri, Francesco Garzotto, Zaccaria Ricci, Stuart L. Goldstein, Xiaoqiang Ding, Jiarui Xu, Claudio Ronco

01.12.2017 | Review | Ausgabe 1/2017 Open Access

The hospital of tomorrow in 10 points

Jean-Louis Vincent, Jacques Creteur

01.12.2017 | Erratum | Ausgabe 1/2017 Open Access

Erratum to: Pre-hospital management of mass casualty civilian shootings: a systematic literature review

Conor D. A. Turner, David J. Lockey, Marius Rehn

01.12.2017 | Erratum | Ausgabe 1/2017 Open Access

Erratum to: Can calculation of energy expenditure based on CO2 measurements replace indirect calorimetry?

Taku Oshima, Séverine Graf, Claudia-Paula Heidegger, Laurence Genton, Jérôme Pugin, Claude Pichard

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Early predictors of poor outcome after out-of-hospital cardiac arrest

Louise Martinell, Niklas Nielsen, Johan Herlitz, Thomas Karlsson, Janneke Horn, Matt P. Wise, Johan Undén, Christian Rylander

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Plasma metabolomics for the diagnosis and prognosis of H1N1 influenza pneumonia

Mohammad M. Banoei, Hans J. Vogel, Aalim M. Weljie, Anand Kumar, Sachin Yende, Derek C. Angus, Brent W. Winston, the Canadian Critical Care Translational Biology Group (CCCTBG)

01.12.2017 | Erratum | Ausgabe 1/2017 Open Access

Erratum to: Cardiac ischemia in patients with septic shock randomized to vasopressin or norepinephrine

Sangeeta Mehta, John Granton, Anthony C. Gordon, Deborah J. Cook, Stephen Lapinsky, Gary Newton, Kris Bandayrel, Anjuli Little, Chuin Siau, Dieter Ayers, Joel Singer, Terry C. K. Lee, Keith R. Walley, Michelle Storms, D. James Cooper, Cheryl L. Holmes, Paul Hebert, Jeffrey Presneill, James A. Russell, for the Vasopressin and Septic Shock Trial (VASST) Investigators

01.12.2017 | Letter | Ausgabe 1/2017 Open Access

Bacteriophage lysins as antibacterials

Umender Sharma, Vivek D. Paul

01.12.2017 | Letter | Ausgabe 1/2017 Open Access

A brief comment on vaccinations for opportunistic microorganisms

Ferhat Arslan, Haluk Vahaboğlu

01.12.2017 | Letter | Ausgabe 1/2017 Open Access

Understanding the null hypothesis (H0) in non-inferiority trials

Jihad Mallat

01.12.2017 | Commentary | Ausgabe 1/2017 Open Access

Blood pressure deficits in acute kidney injury: not all about the mean arterial pressure?

Lui G. Forni, Michael Joannidis

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Myocardial and haemodynamic responses to two fluid regimens in African children with severe malnutrition and hypovolaemic shock (AFRIM study)

Nchafatso Obonyo, Bernadette Brent, Peter Olupot-Olupot, Michael Boele van Hensbroek, Irene Kuipers, Sidney Wong, Kenji Shiino, Jonathan Chan, John Fraser, Job B. M. van Woensel, Kathryn Maitland

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Association between fluid intake and mortality in critically ill patients with negative fluid balance: a retrospective cohort study

Yanfei Shen, Xinmei Huang, Weimin Zhang

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Time course of blood lactate levels, inflammation, and mitochondrial function in experimental sepsis

Thiago Domingos Corrêa, Adriano José Pereira, Sebastian Brandt, Madhusudanarao Vuda, Siamak Djafarzadeh, Jukka Takala, Stephan Mathias Jakob

01.12.2017 | Viewpoint | Ausgabe 1/2017 Open Access

High protein intake without concerns?

Olav Rooyackers, Martin Sundström Rehal, Felix Liebau, Åke Norberg, Jan Wernerman

01.12.2017 | Erratum | Ausgabe 1/2017 Open Access

Erratum to: Contribution of Candida biomarkers and DNA detection for the diagnosis of invasive candidiasis in ICU patients with severe abdominal conditions

Cristóbal León, Sergio Ruiz-Santana, Pedro Saavedra, Carmen Castro, Ana Loza, Ismail Zakariya, Alejandro Úbeda, Manuel Parra, Desirée Macías, José Ignacio Tomás, Antonio Rezusta, Alejandro Rodríguez, Frederic Gómez, Estrella Martín-Mazuelos, The Cava Trem Study Group

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Simvastatin for patients with acute respiratory distress syndrome: long-term outcomes and cost-effectiveness from a randomised controlled trial

A. Agus, C. Hulme, R. M. Verghis, C. McDowell, C. Jackson, C. M. O’Kane, J. G. Laffey, D. F. McAuley

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Cost analysis of the very elderly admitted to intensive care units

Nicolas Chin-Yee, Gianni D’Egidio, Kednapa Thavorn, Daren Heyland, Kwadwo Kyeremanteng

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Pre-admission functional status impacts the performance of the APACHE IV model of mortality prediction in critically ill patients

James S. Krinsley, Thomas Wasser, Gina Kang, Sean M. Bagshaw

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Early EEG for outcome prediction of postanoxic coma: prospective cohort study with cost-minimization analysis

Lotte Sondag, Barry J. Ruijter, Marleen C. Tjepkema-Cloostermans, Albertus Beishuizen, Frank H. Bosch, Janine A. van Til, Michel J. A. M. van Putten, Jeannette Hofmeijer

01.12.2017 | Letter | Ausgabe 1/2017 Open Access

Video vs direct laryngoscopy in the ICU: are we asking the right question?

Michael Chaim Sklar, Stephen Lapinsky

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Comparison of fluid balance and hemodynamic and metabolic effects of sodium lactate versus sodium bicarbonate versus 0.9% NaCl in porcine endotoxic shock: a randomized, open-label, controlled study

Thibault Duburcq, Arthur Durand, Anne-Frédérique Dessein, Joseph Vamecq, Jean-Claude Vienne, Dries Dobbelaere, Karine Mention, Claire Douillard, Patrice Maboudou, Valery Gmyr, François Pattou, Mercé Jourdain, Fabienne Tamion, Julien Poissy, Daniel Mathieu, Raphaël Favory

01.12.2017 | Editorial | Ausgabe 1/2017 Open Access

Obesity and survival in critically ill patients with acute respiratory distress syndrome: a paradox within the paradox

Lorenzo Ball, Ary Serpa Neto, Paolo Pelosi

01.12.2017 | Letter | Ausgabe 1/2017 Open Access

Echocardiography accurately predicts pulmonary hypertension in patients with advanced lung disease

Silvia Cottini, Christian Benden, Lars C. Huber, Mattia Arrigo

01.12.2017 | Letter | Ausgabe 1/2017 Open Access

Diaphragm electrical activity monitoring as a breakpoint in the management of a tetraplegic child

Guillaume Mortamet, François Proulx, Benjamin Crulli, Nadia Savy, Philippe Jouvet, Guillaume Emeriaud

01.12.2017 | Letter | Ausgabe 1/2017 Open Access

No-touch methods of terminal cleaning in the intensive care unit: results from the first large randomized trial with patient-centred outcomes

Vincenzo Russotto, Andrea Cortegiani, Pasquale Iozzo, Santi Maurizio Raineri, Cesare Gregoretti, Antonino Giarratano

01.12.2017 | Letter | Ausgabe 1/2017 Open Access

Efficient organisation of intensive care units with a focus on quality: the non-physician provider

Herman Gerhard Kreeftenberg, Sjaak Pouwels, Peter Henricus Johannes van der Voort

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Timing of appropriate empirical antimicrobial administration and outcome of adults with community-onset bacteremia

Ching-Chi Lee, Chung-Hsun Lee, Ming-Yuan Hong, Hung-Jen Tang, Wen-Chien Ko

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Circulating microparticle levels are reduced in patients with ARDS

Ciara M. Shaver, Justin Woods, Jennifer K. Clune, Brandon S. Grove, Nancy E. Wickersham, J. Brennan McNeil, Gregory Shemancik, Lorraine B. Ware, Julie A. Bastarache

01.12.2017 | Letter | Ausgabe 1/2017 Open Access

A critical age: can we reliably measure frailty in critical care?

Richard J. Pugh, Chris M. Thorpe, Christian P. Subbe

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Outcome of acute respiratory distress syndrome in university and non-university hospitals in Germany

Konstantinos Raymondos, Tamme Dirks, Michael Quintel, Ulrich Molitoris, Jörg Ahrens, Thorben Dieck, Kai Johanning, Dietrich Henzler, Rolf Rossaint, Christian Putensen, Hermann Wrigge, Ralph Wittich, Maximilian Ragaller, Thomas Bein, Martin Beiderlinden, Maxi Sanmann, Christian Rabe, Jörn Schlechtweg, Monika Holler, Fernando Frutos-Vivar, Andres Esteban, Hartmut Hecker, Simone Rosseau, Vera von Dossow, Claudia Spies, Tobias Welte, Siegfried Piepenbrock, Steffen Weber-Carstens

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Heat and moisture exchangers (HMEs) and heated humidifiers (HHs) in adult critically ill patients: a systematic review, meta-analysis and meta-regression of randomized controlled trials

Maria Vargas, Davide Chiumello, Yuda Sutherasan, Lorenzo Ball, Antonio M. Esquinas, Paolo Pelosi, Giuseppe Servillo

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Critical care at the end of life: a population-level cohort study of cost and outcomes

Dipayan Chaudhuri, Peter Tanuseputro, Brent Herritt, Gianni D’Egidio, Mathieu Chalifoux, Kwadwo Kyeremanteng

01.12.2017 | Editorial | Ausgabe 1/2017 Open Access

How could we enhance translation of sepsis immunology to inform immunomodulation trials in sepsis?

M. Shankar-Hari

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Effects of neurally adjusted ventilatory assist on air distribution and dead space in patients with acute exacerbation of chronic obstructive pulmonary disease

Qin Sun, Ling Liu, Chun Pan, Zhanqi Zhao, Jingyuan Xu, Airan Liu, Haibo Qiu

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Trials directly comparing alternative spontaneous breathing trial techniques: a systematic review and meta-analysis

Karen E. A. Burns, Ibrahim Soliman, Neill K. J. Adhikari, Amer Zwein, Jessica T. Y. Wong, Carolina Gomez-Builes, Jose Augusto Pellegrini, Lu Chen, Nuttapol Rittayamai, Michael Sklar, Laurent J. Brochard, Jan O. Friedrich

01.12.2017 | Letter | Ausgabe 1/2017 Open Access

Resting energy expenditure and optimal nutrition in critical care: how to guide our calorie prescriptions

Oren Zusman, Pierre Singer

01.12.2017 | Letter | Ausgabe 1/2017 Open Access

Use of bacteriophages in the treatment of colistin-only-sensitive Pseudomonas aeruginosa septicaemia in a patient with acute kidney injury—a case report

Serge Jennes, Maia Merabishvili, Patrick Soentjens, Kim Win Pang, Thomas Rose, Elkana Keersebilck, Olivier Soete, Pierre-Michel François, Simona Teodorescu, Gunther Verween, Gilbert Verbeken, Daniel De Vos, Jean-Paul Pirnay

01.12.2017 | Letter | Ausgabe 1/2017 Open Access

Daily cost of delay to adequate antibiotic treatment among patients surviving a hospitalization with community-onset Acinetobacter baumannii pneumonia or sepsis

Marya D. Zilberberg, Brian H. Nathanson, Kate Sulham, Weihong Fan, Andrew F. Shorr

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Role of nutrition support in adult cardiac surgery: a consensus statement from an International Multidisciplinary Expert Group on Nutrition in Cardiac Surgery

Christian Stoppe, Andreas Goetzenich, Glenn Whitman, Rika Ohkuma, Trish Brown, Roupen Hatzakorzian, Arnold Kristof, Patrick Meybohm, Jefferey Mechanick, Adam Evans, Daniel Yeh, Bernard McDonald, Michael Chourdakis, Philip Jones, Richard Barton, Ravi Tripathi, Gunnar Elke, Oliver Liakopoulos, Ravi Agarwala, Vladimir Lomivorotov, Ekaterina Nesterova, Gernot Marx, Carina Benstoem, Margot Lemieux, Daren K. Heyland

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Effect sizes in ongoing randomized controlled critical care trials

Elliott E. Ridgeon, Rinaldo Bellomo, Scott K. Aberegg, Rob Mac Sweeney, Rachel S. Varughese, Giovanni Landoni, Paul J. Young

01.12.2017 | Editorial | Ausgabe 1/2017 Open Access

Fourth Surviving Sepsis Campaign’s hemodynamic recommendations: a step forward or a return to chaos?

Glenn Hernández, Jean-Louis Teboul

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Potential survival benefit of polymyxin B hemoperfusion in patients with septic shock: a propensity-matched cohort study

Yoshihiko Nakamura, Taisuke Kitamura, Fumiaki Kiyomi, Mineji Hayakawa, Kota Hoshino, Yasumasa Kawano, Reiko Yamasaki, Takeshi Nishida, Mariko Mizunuma, Hiroyasu Ishikura, Japan Septic Disseminated Intravascular Coagulation (JSEPTIC DIC) study group

01.12.2017 | Research | Ausgabe 1/2017 Open Access

The negative effect of initial high-dose methylprednisolone and tapering regimen for acute respiratory distress syndrome: a retrospective propensity matched cohort study

Makoto Takaki, Kazuya Ichikado, Kodai Kawamura, Yasuhiro Gushima, Moritaka Suga

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Transthoracic echocardiography: an accurate and precise method for estimating cardiac output in the critically ill patient

Pablo Mercado, Julien Maizel, Christophe Beyls, Dimitri Titeca-Beauport, Magalie Joris, Loay Kontar, Antoine Riviere, Olivier Bonef, Thierry Soupison, Christophe Tribouilloy, Bertrand de Cagny, Michel Slama

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Severe varicella-zoster virus pneumonia: a multicenter cohort study

Adrien Mirouse, Philippe Vignon, Prescillia Piron, René Robert, Laurent Papazian, Guillaume Géri, Pascal Blanc, Christophe Guitton, Claude Guérin, Naïke Bigé, Antoine Rabbat, Aurélie Lefebvre, Keyvan Razazi, Muriel Fartoukh, Eric Mariotte, Lila Bouadma, Jean-Damien Ricard, Amélie Seguin, Bertrand Souweine, Anne-Sophie Moreau, Stanislas Faguer, Arnaud Mari, Julien Mayaux, Francis Schneider, Annabelle Stoclin, Pierre Perez, Julien Maizel, Charles Lafon, Frédérique Ganster, Laurent Argaud, Christophe Girault, François Barbier, Lucien Lecuyer, Jérôme Lambert, Emmanuel Canet

01.12.2017 | Editorial | Ausgabe 1/2017 Open Access

Between chromatin and SNPs: genetic variability and the susceptibility to acute kidney injury

Hernando Gómez

01.12.2017 | Research | Ausgabe 1/2017 Open Access

A randomized controlled pilot study to evaluate the effect of an enteral formulation designed to improve gastrointestinal tolerance in the critically ill patient—the SPIRIT trial

Stephan M. Jakob, Lukas Bütikofer, David Berger, Michael Coslovsky, Jukka Takala

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Effect of perioperative goal-directed hemodynamic therapy on postoperative recovery following major abdominal surgery—a systematic review and meta-analysis of randomized controlled trials

Yanxia Sun, Fang Chai, Chuxiong Pan, Jamie Lee Romeiser, Tong J. Gan

01.12.2017 | Research | Ausgabe 1/2017 Open Access

A randomized trial of supplemental parenteral nutrition in underweight and overweight critically ill patients: the TOP-UP pilot trial

Paul E. Wischmeyer, Michel Hasselmann, Christine Kummerlen, Rosemary Kozar, Demetrios James Kutsogiannis, Constantine J. Karvellas, Beth Besecker, David K. Evans, Jean-Charles Preiser, Leah Gramlich, Khursheed Jeejeebhoy, Rupinder Dhaliwal, Xuran Jiang, Andrew G. Day, Daren K. Heyland

01.12.2017 | Commentary | Ausgabe 1/2017 Open Access

Systematic assessment of advanced respiratory physiology: precision medicine entering real-life ICU?

Tommaso Mauri, Giacomo Grasselli, Antonio Pesenti

01.12.2017 | Letter | Ausgabe 1/2017 Open Access

Antiarrhythmic drugs in out-of-hospital cardiac arrest: is there a place for potassium chloride?

Romain Jouffroy, Benoît Vivien

01.12.2017 | Letter | Ausgabe 1/2017 Open Access

Assessment of pulmonary mechanics in mechanical ventilation

Federico Gordo, Beatriz Lobo-Valbuena

01.12.2017 | Viewpoint | Ausgabe 1/2017 Open Access

Optimal timing of renal replacement therapy initiation in acute kidney injury: the elephant felt by the blindmen?

Chih-Chung Shiao, Tao-Min Huang, Herbert D. Spapen, Patrick M. Honore, Vin-Cent Wu

01.12.2017 | Review | Ausgabe 1/2017 Open Access

Transpulmonary thermodilution: advantages and limits

Xavier Monnet, Jean-Louis Teboul

01.12.2017 | Commentary | Ausgabe 1/2017 Open Access

Retinal involvement in sepsis: from the eye of the patient to the eye of the beholder

E. Christiaan Boerma

01.12.2017 | Letter | Ausgabe 1/2017 Open Access

Human leukocyte antigen-DR expression might predict outcomes in severe sepsis, but diabetes mellitus cannot be ignored

Jun Li, Xianshi Zhou, Ye Ye, Guanghua Guanghua

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Early versus late initiation of renal replacement therapy impacts mortality in patients with acute kidney injury post cardiac surgery: a meta-analysis

Honghong Zou, Qianwen Hong, Gaosi XU

01.12.2017 | Letter | Ausgabe 1/2017 Open Access

On-line plasma lactate concentration monitoring in critically ill patients

Christian De Tymowski, Sabri Soussi, François Depret, Matthieu Legrand

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Untangling glycaemia and mortality in critical care

Vincent Uyttendaele, Jennifer L. Dickson, Geoffrey M. Shaw, Thomas Desaive, J. Geoffrey Chase

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Protein S100 as outcome predictor after out-of-hospital cardiac arrest and targeted temperature management at 33 °C and 36 °C

Pascal Stammet, Josef Dankiewicz, Niklas Nielsen, François Fays, Olivier Collignon, Christian Hassager, Michael Wanscher, Johan Undèn, Jorn Wetterslev, Tommaso Pellis, Anders Aneman, Jan Hovdenes, Matt P. Wise, Georges Gilson, David Erlinge, Janneke Horn, Tobias Cronberg, Michael Kuiper, Jesper Kjaergaard, Yvan Gasche, Yvan Devaux, Hans Friberg, Target Temperature Management after Out-of-Hospital Cardiac Arrest (TTM) trial investigators

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Nucleated red blood cells, critical illness survivors and postdischarge outcomes: a cohort study

Steven W. Purtle, Clare M. Horkan, Takuhiro Moromizato, Fiona K. Gibbons, Kenneth B. Christopher

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Marked regional endothelial dysfunction in mottled skin area in patients with severe infections

Simon Bourcier, Jérémie Joffre, Vincent Dubée, Gabriel Preda, Jean-Luc Baudel, Naïke Bigé, Guillaume Leblanc, Bernard I. Levy, Bertrand Guidet, Eric Maury, Hafid Ait-Oufella

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Impact of Gram stain results on initial treatment selection in patients with ventilator-associated pneumonia: a retrospective analysis of two treatment algorithms

Jumpei Yoshimura, Takahiro Kinoshita, Kazuma Yamakawa, Asako Matsushima, Naoki Nakamoto, Toshimitsu Hamasaki, Satoshi Fujimi

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Influence of low-flow time on survival after extracorporeal cardiopulmonary resuscitation (eCPR)

Tobias Wengenmayer, Stephan Rombach, Florian Ramshorn, Paul Biever, Christoph Bode, Daniel Duerschmied, Dawid L. Staudacher

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Transcriptome modulation by hydrocortisone in severe burn shock: ancillary analysis of a prospective randomized trial

Jonathan Plassais, Fabienne Venet, Marie-Angélique Cazalis, Diane Le Quang, Alexandre Pachot, Guillaume Monneret, Sylvie Tissot, Julien Textoris

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Hemoglobin concentrations and RBC transfusion thresholds in patients with acute brain injury: an international survey

Rafael Badenes, Mauro Oddo, José I. Suarez, Massimo Antonelli, Jeffrey Lipman, Giuseppe Citerio, Fabio Silvio Taccone

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Low-volume resuscitation with normal saline is associated with microvascular endothelial dysfunction after hemorrhage in rats, compared to colloids and balanced crystalloids

Luciana N. Torres, Kevin K. Chung, Christi L. Salgado, Michael A. Dubick, Ivo P. Torres Filho

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Evaluation of early antimicrobial therapy adaptation guided by the BetaLACTA® test: a case-control study

Marc Garnier, Sacha Rozencwajg, Tài Pham, Sophie Vimont, Clarisse Blayau, Mehdi Hafiani, Jean-Pierre Fulgencio, Francis Bonnet, Jean-Luc Mainardi, Guillaume Arlet, Muriel Fartoukh, Salah Gallah, Christophe Quesnel

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Treatment of severe hospital-acquired and ventilator-associated pneumonia: a systematic review of inclusion and judgment criteria used in randomized controlled trials

Emmanuel Weiss, Wafa Essaied, Christophe Adrie, Jean-Ralph Zahar, Jean-François Timsit

01.12.2017 | Letter | Ausgabe 1/2017 Open Access

Does anti-VEGF bevacizumab improve survival in experimental sepsis?

Emmanuel Besnier, Ebba Brakenhielm, Vincent Richard, Fabienne Tamion

01.12.2017 | Letter | Ausgabe 1/2017 Open Access

The usability of ventilators: a comparative evaluation of use safety and user experience—an editorial response

Edwin Coombs

01.12.2017 | Letter | Ausgabe 1/2017 Open Access

How to remove the grey area between ventilator-associated pneumonia and ventilator-associated tracheobronchitis?

Yuetian Yu, Cheng Zhu, Chunyan Liu, Yuan Gao

01.12.2017 | Letter | Ausgabe 1/2017 Open Access

Is it time to consider visual feedback systems the gold standard for chest compression skill acquisition?

Andrea Cortegiani, Vincenzo Russotto, Enrico Baldi, Enrico Contri, Santi Maurizio Raineri, Antonino Giarratano

01.12.2017 | Letter | Ausgabe 1/2017 Open Access

Limited evidence to recommend lactate kinetics-guided therapy

Daniel O. Thomas-Rüddel, Michael Bauer

01.12.2017 | Letter | Ausgabe 1/2017 Open Access

Do we need another prognostic score for cardiogenic shock patients with ECMO?

Sébastien Champion

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Open-chest versus closed-chest cardiopulmonary resuscitation in blunt trauma: analysis of a nationwide trauma registry

Akira Endo, Atsushi Shiraishi, Yasuhiro Otomo, Makoto Tomita, Hiroki Matsui, Kiyoshi Murata

01.12.2017 | Research | Ausgabe 1/2017 Open Access

New setting of neurally adjusted ventilatory assist for noninvasive ventilation by facial mask: a physiologic study

Federico Longhini, Chun Pan, Jianfeng Xie, Gianmaria Cammarota, Andrea Bruni, Eugenio Garofalo, Yi Yang, Paolo Navalesi, Haibo Qiu

01.12.2017 | Research | Ausgabe 1/2017 Open Access

The common promoter polymorphism rs11666254 downregulates FPR2/ALX expression and increases risk of sepsis in patients with severe trauma

Han Zhang, Yao Lu, Guixiang Sun, Fang Teng, Nian Luo, Jianxin Jiang, Aiqing Wen

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Association of neuron-specific enolase values with outcomes in cardiac arrest survivors is dependent on the time of sample collection

Dagmar Vondrakova, Andreas Kruger, Marek Janotka, Filip Malek, Vlasta Dudkova, Petr Neuzil, Petr Ostadal

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Double carbapenem as a rescue strategy for the treatment of severe carbapenemase-producing Klebsiella pneumoniae infections: a two-center, matched case–control study

Gennaro De Pascale, Gennaro Martucci, Luca Montini, Giovanna Panarello, Salvatore Lucio Cutuli, Daniele Di Carlo, Valentina Di Gravio, Roberta Di Stefano, Guido Capitanio, Maria Sole Vallecoccia, Piera Polidori, Teresa Spanu, Antonio Arcadipane, Massimo Antonelli

01.12.2017 | Editorial | Ausgabe 1/2017 Open Access

Decisions regarding admission to the ICU and international initiatives to improve the decision-making process

Christopher Bassford

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Detecting impaired myocardial relaxation in sepsis with a novel tissue Doppler parameter (septal e′/s′)

David J. Clancy, Michel Slama, Stephen Huang, Timothy Scully, Anthony S. McLean, Sam R. Orde

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Combined use of serum (1,3)-β-d-glucan and procalcitonin for the early differential diagnosis between candidaemia and bacteraemia in intensive care units

Daniele Roberto Giacobbe, Malgorzata Mikulska, Mario Tumbarello, Elisa Furfaro, Marzia Spadaro, Angela Raffaella Losito, Alessio Mesini, Gennaro De Pascale, Anna Marchese, Marco Bruzzone, Paolo Pelosi, Michele Mussap, Alexandre Molin, Massimo Antonelli, Brunella Posteraro, Maurizio Sanguinetti, Claudio Viscoli, Valerio Del Bono, on behalf of ISGRI-SITA (Italian Study Group on Resistant Infections of the Società Italiana Terapia Antinfettiva)

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Electrical impedance tomography for predicting failure of spontaneous breathing trials in patients with prolonged weaning

Johannes Bickenbach, Michael Czaplik, Mareike Polier, Gernot Marx, Nikolaus Marx, Michael Dreher

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Protocol based invasive intracranial pressure monitoring in acute liver failure: feasibility, safety and impact on management

Venkatakrishna Rajajee, Robert J. Fontana, Anthony J. Courey, Parag G. Patil

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Outcomes of subsyndromal delirium in ICU: a systematic review and meta-analysis

Rodrigo B. Serafim, Marcio Soares, Fernando A. Bozza, José R. Lapa e Silva, Felipe Dal-Pizzol, Maria Carolina Paulino, Pedro Povoa, Jorge I. F. Salluh

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Enhanced antimicrobial de-escalation for pneumonia in mechanically ventilated patients: a cross-over study

Tracy Trupka, Kristen Fisher, Scott T. Micek, Paul Juang, Marin H. Kollef

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Low-dose immunoglobulin G is not associated with mortality in patients with sepsis and septic shock

Yusuke Iizuka, Masamitsu Sanui, Yusuke Sasabuchi, Alan Kawarai Lefor, Mineji Hayakawa, Shinjiro Saito, Shigehiko Uchino, Kazuma Yamakawa, Daisuke Kudo, Kohei Takimoto, Toshihiko Mayumi, Takeo Azuhata, Fumihito Ito, Shodai Yoshihiro, Katsura Hayakawa, Tsuyoshi Nakashima, Takayuki Ogura, Eiichiro Noda, Yoshihiko Nakamura, Ryosuke Sekine, Yoshiaki Yoshikawa, Motohiro Sekino, Keiko Ueno, Yuko Okuda, Masayuki Watanabe, Akihito Tampo, Nobuyuki Saito, Yuya Kitai, Hiroki Takahashi, Iwao Kobayashi, Yutaka Kondo, Wataru Matsunaga, Sho Nachi, Toru Miike, Hiroshi Takahashi, Shuhei Takauji, Kensuke Umakoshi, Takafumi Todaka, Hiroshi Kodaira, Kohkichi Andoh, Takehiko Kasai, Yoshiaki Iwashita, Hideaki Arai, Masato Murata, Masahiro Yamane, Kazuhiro Shiga, Naoto Hori

01.12.2017 | Erratum | Ausgabe 1/2017 Open Access

Erratum to: P95 B-lines on chest ultrasound predicts elevated left ventricular diastolic pressures

Z. Bitar, O. Maadarani, R. Al Hamdan

01.12.2017 | Review | Ausgabe 1/2017 Open Access

The future of mechanical ventilation: lessons from the present and the past

Luciano Gattinoni, John J. Marini, Francesca Collino, Giorgia Maiolo, Francesca Rapetti, Tommaso Tonetti, Francesco Vasques, Michael Quintel

01.12.2017 | Research | Ausgabe 1/2017 Open Access

High-flow nasal cannula oxygen therapy is superior to conventional oxygen therapy but not to noninvasive mechanical ventilation on intubation rate: a systematic review and meta-analysis

Huiying Zhao, Huixia Wang, Feng Sun, Shan Lyu, Youzhong An

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Association of baseline steroid use with long-term rates of infection and sepsis in the REGARDS cohort

Ninad S. Chaudhary, John P. Donnelly, Justin X. Moore, John W. Baddley, Monika M. Safford, Henry E. Wang

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Monocyte programmed death ligand-1 expression is an early marker for predicting infectious complications in acute pancreatitis

Tingting Pan, Tianyun Zhou, Lei Li, Zhaojun Liu, Ying Chen, Enqiang Mao, Meiling Li, Hongping Qu, Jialin Liu

01.12.2017 | Erratum | Ausgabe 1/2017 Open Access

Erratum to: Shock induced endotheliopathy (SHINE) in acute critical illness - a unifying pathophysiologic mechanism

Pär Ingemar Johansson, Jakob Stensballe, Sisse Rye Ostrowski

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Severity of acute gastrointestinal injury grade is a predictor of all-cause mortality in critically ill patients: a multicenter, prospective, observational study

Bangchuan Hu, Renhua Sun, Aiping Wu, Yin Ni, Jingquan Liu, Feng Guo, Lijun Ying, Guoping Ge, Aijun Ding, Yunchao Shi, Changwen Liu, Lei Xu, Ronglin Jiang, Jun Lu, Ronghai Lin, Yannan Zhu, Weidong Wu, Bo Xie

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Markers of nitric oxide are associated with sepsis severity: an observational study

Martin Sebastian Winkler, Stefan Kluge, Maximilian Holzmann, Eileen Moritz, Linda Robbe, Antonia Bauer, Corinne Zahrte, Marion Priefler, Edzard Schwedhelm, Rainer H. Böger, Alwin E. Goetz, Axel Nierhaus, Christian Zoellner

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Prolonged acute care and post-acute care admission and recovery of physical function in survivors of acute respiratory failure: a secondary analysis of a randomized controlled trial

Anna Neumeier, Amy Nordon-Craft, Dan Malone, Margaret Schenkman, Brendan Clark, Marc Moss

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Evidence of altered haemostasis in an ovine model of venovenous extracorporeal membrane oxygenation support

Margaret R. Passmore, Yoke L. Fung, Gabriela Simonova, Samuel R. Foley, Sara D. Diab, Kimble R. Dunster, Michelle M. Spanevello, Charles I. McDonald, John-Paul Tung, Natalie M. Pecheniuk, Karen Hay, Kiran Shekar, John F. Fraser

01.12.2017 | Research | Ausgabe 1/2017 Open Access

A systematic review and meta-analysis comparing mortality in pre-hospital tracheal intubation to emergency department intubation in trauma patients

Espen Fevang, Zane Perkins, David Lockey, Elisabeth Jeppesen, Hans Morten Lossius

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Metabolome alterations in severe critical illness and vitamin D status

Jessica Lasky-Su, Amber Dahlin, Augusto A. Litonjua, Angela J. Rogers, Michael J. McGeachie, Rebecca M. Baron, Lee Gazourian, Diana Barragan-Bradford, Laura E. Fredenburgh, Augustine M. K. Choi, Kris M. Mogensen, Sadeq A. Quraishi, Karin Amrein, Kenneth B. Christopher

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Inhaled AP301 for treatment of pulmonary edema in mechanically ventilated patients with acute respiratory distress syndrome: a phase IIa randomized placebo-controlled trial

Katharina Krenn, Rudolf Lucas, Adrien Croizé, Stefan Boehme, Klaus Ulrich Klein, Robert Hermann, Klaus Markstaller, Roman Ullrich

01.12.2017 | Commentary | Ausgabe 1/2017 Open Access

Care at a non-university hospital: an independent risk factor for mortality in ARDS?

Bourke Tillmann, Hannah Wunsch

01.12.2017 | Letter | Ausgabe 1/2017 Open Access

Targeted therapeutic mild hypercapnia after cardiac arrest

Glenn M. Eastwood, Alistair Nichol, Matt P. Wise

01.12.2017 | Review | Ausgabe 1/2017 Open Access

Continuous glucose monitoring in the ICU: clinical considerations and consensus

James S. Krinsley, J. Geoffrey Chase, Jan Gunst, Johan Martensson, Marcus J. Schultz, Fabio S. Taccone, Jan Wernerman, Julien Bohe, Christophe De Block, Thomas Desaive, Pierre Kalfon, Jean-Charles Preiser

01.12.2017 | Letter | Ausgabe 1/2017 Open Access

Dexmedetomidine as a promising prevention strategy for cardiac surgery-associated acute kidney injury: a meta-analysis

Rui Shi, Hong-Tao Tie

01.12.2017 | Viewpoint | Ausgabe 1/2017 Open Access

Driving pressure: a marker of severity, a safety limit, or a goal for mechanical ventilation?

Guillermo Bugedo, Jaime Retamal, Alejandro Bruhn

01.12.2017 | Letter | Ausgabe 1/2017 Open Access

Plasma concentrations of caspofungin in a critically ill patient with morbid obesity

Rafael Ferriols-Lisart, Gerardo Aguilar, Alejandro Pérez-Pitarch, Jaume Puig, Carlos Ezquer-Garín, Manuel Alós

01.12.2017 | Letter | Ausgabe 1/2017 Open Access

Response to: Understanding the null hypothesis (H0) in non-inferiority trials

Xiang Zhou, Dawei Liu, Longxiang Su

01.12.2017 | Viewpoint | Ausgabe 1/2017 Open Access

Hyperglycaemia in critically ill patients: the immune system’s sweet tooth

Gustav van Niekerk, Tanja Davis, Anna-Mart Engelbrecht

01.12.2017 | Letter | Ausgabe 1/2017 Open Access

Confounding variables impacting the association between duration of veno-arterial extracorporeal life support and mortality

Jesse Kiefer, Robert E. Freundlich

01.12.2017 | Editorial | Ausgabe 1/2017 Open Access

Understanding fluid administration approaches in children with co-morbidities and septic shock

Niranjan Kissoon

01.12.2017 | Letter | Ausgabe 1/2017 Open Access

Relapsing fever in young refugees from East Africa

Spinello Antinori, Valeria Colombo, Mario Corbellino

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Could remifentanil reduce duration of mechanical ventilation in comparison with other opioids for mechanically ventilated patients? A systematic review and meta-analysis

Yibing Zhu, Yinhua Wang, Bin Du, Xiuming Xi

01.12.2017 | Research | Ausgabe 1/2017 Open Access

What is the impact of the fluid challenge technique on diagnosis of fluid responsiveness? A systematic review and meta-analysis

Laura Toscani, Hollmann D. Aya, Dimitra Antonakaki, Davide Bastoni, Ximena Watson, Nish Arulkumaran, Andrew Rhodes, Maurizio Cecconi

01.12.2017 | Editorial | Ausgabe 1/2017 Open Access

Rapid identification of antimicrobial resistance patterns allows a faster antibiotic adequacy

Adrian Ceccato, Otavio T. Ranzani, Antoni Torres

01.12.2017 | Editorial | Ausgabe 1/2017 Open Access

Recovery from critical illness-induced organ failure: the role of autophagy

Jan Gunst

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Voluntary running exercise protects against sepsis-induced early inflammatory and pro-coagulant responses in aged mice

Karel Tyml, Scott Swarbreck, Cynthia Pape, Dan Secor, James Koropatnick, Qingping Feng, Ruud A. W. Veldhuizen, Sean E. Gill

01.12.2017 | Review | Ausgabe 1/2017 Open Access

Incidence, prevalence, and management of MRSA bacteremia across patient populations—a review of recent developments in MRSA management and treatment

Ali Hassoun, Peter K. Linden, Bruce Friedman

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Software-guided versus nurse-directed blood glucose control in critically ill patients: the LOGIC-2 multicenter randomized controlled clinical trial

Jasperina Dubois, Tom Van Herpe, Roosmarijn T. van Hooijdonk, Ruben Wouters, Domien Coart, Pieter Wouters, Aimé Van Assche, Guy Veraghtert, Bart De Moor, Joost Wauters, Alexander Wilmer, Marcus J. Schultz, Greet Van den Berghe, Dieter Mesotten

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Selepressin, a novel selective vasopressin V1A agonist, is an effective substitute for norepinephrine in a phase IIa randomized, placebo-controlled trial in septic shock patients

James A. Russell, Jean-Louis Vincent, Anne Louise Kjølbye, Håkan Olsson, Allan Blemings, Herbert Spapen, Peder Carl, Pierre-Francois Laterre, Lars Grundemar

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Dehydroepiandrosterone sulfate and dehydroepiandrosterone sulfate/cortisol ratio in cirrhotic patients with septic shock: another sign of hepatoadrenal syndrome?

Ming-Hung Tsai, Hui-Chun Huang, Yun-Shing Peng, Yung-Chang Chen, Ya-Chung Tian, Chih-Wei Yang, Jau-Min Lien, Ji-Tseng Fang, Cheng-Shyong Wu, Sen-Yung Hsieh, Fa-Yauh Lee

01.12.2017 | Letter | Ausgabe 1/2017 Open Access

Point-of-care ultrasonography: a practical step in the path to precision in critical care

Gentle Sunder Shrestha

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Early troponin I in critical illness and its association with hospital mortality: a cohort study

Annemarie B. Docherty, Malcolm Sim, Joao Oliveira, Michael Adlam, Marlies Ostermann, Timothy S. Walsh, John Kinsella, Nazir I. Lone

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Circulating levels of soluble Fas (sCD95) are associated with risk for development of a nonresolving acute kidney injury subphenotype

Pavan K. Bhatraju, Cassianne Robinson-Cohen, Carmen Mikacenic, Susanna Harju-Baker, Victoria Dmyterko, Natalie S. J. Slivinski, W. Conrad Liles, Jonathan Himmelfarb, Susan R. Heckbert, Mark M. Wurfel

01.12.2017 | Research | Ausgabe 1/2017 Open Access

The association of early combined lactate and glucose levels with subsequent renal and liver dysfunction and hospital mortality in critically ill patients

Pedro Freire Jorge, Nienke Wieringa, Eva de Felice, Iwan C. C. van der Horst, Annemieke Oude Lansink, Maarten W. Nijsten

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Disseminated intravascular coagulation with increased fibrinolysis during the early phase of isolated traumatic brain injury

Takeshi Wada, Satoshi Gando, Kunihiko Maekaw, Kenichi Katabami, Hisako Sageshima, Mineji Hayakawa, Atsushi Sawamura

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Costs and expected gain in lifetime health from intensive care versus general ward care of 30,712 individual patients: a distribution-weighted cost-effectiveness analysis

Frode Lindemark, Øystein A. Haaland, Reidar Kvåle, Hans Flaatten, Ole F. Norheim, Kjell A. Johansson

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Recorded time periods of bispectral index values equal to zero predict neurological outcome after out-of-hospital cardiac arrest

Ward Eertmans, Cornelia Genbrugge, Gilles Haesevoets, Jo Dens, Willem Boer, Frank Jans, Cathy De Deyne

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Hyperfibrinolysis in severe isolated traumatic brain injury may occur without tissue hypoperfusion: a retrospective observational multicentre study

Mineji Hayakawa, Kunihiko Maekawa, Shigeki Kushimoto, Hiroshi Kato, Junichi Sasaki, Hiroshi Ogura, Tetsuya Matsuoka, Toshifumi Uejima, Naoto Morimura, Hiroyasu Ishikura, Akiyoshi Hagiwara, Munekazu Takeda, Naoyuki Kaneko, Daizoh Saitoh, Daisuke Kudo, Takashi Kanemura, Takayuki Shibusawa, Shintaro Furugori, Yoshihiko Nakamura, Atsushi Shiraishi, Kiyoshi Murata, Gou Mayama, Arino Yaguchi, Shiei Kim, Osamu Takasu, Kazutaka Nishiyama

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Weekends affect mortality risk and chance of discharge in critically ill patients: a retrospective study in the Austrian registry for intensive care

Paul Zajic, Peter Bauer, Andrew Rhodes, Rui Moreno, Tobias Fellinger, Barbara Metnitz, Faidra Stavropoulou, Martin Posch, Philipp G. H. Metnitz

01.12.2017 | Letter | Ausgabe 1/2017 Open Access

Variability of response to the fluid bolus is again demonstrated

Ellis R. Muggleton

01.12.2017 | Review | Ausgabe 1/2017 Open Access

Ultrasound-guided central venous catheter placement: a structured review and recommendations for clinical practice

Bernd Saugel, Thomas W. L. Scheeren, Jean-Louis Teboul

01.12.2017 | Review | Ausgabe 1/2017 Open Access

The role of nutritional support in the physical and functional recovery of critically ill patients: a narrative review

Danielle E. Bear, Liesl Wandrag, Judith L. Merriweather, Bronwen Connolly, Nicholas Hart, Michael P. W. Grocott, on behalf of the Enhanced Recovery After Critical Illness Programme Group (ERACIP) investigators

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Current clinical nutrition practices in critically ill patients in Latin America: a multinational observational study

Karin Papapietro Vallejo, Carolina Méndez Martínez, Alfredo A. Matos Adames, Vanessa Fuchs-Tarlovsky, Guillermo Carlos Contreras Nogales, Roger Enrique Riofrio Paz, Mario Ignacio Perman, Maria Isabel Toulson Davisson Correia, Dan Linetzky Waitzberg

01.12.2017 | Research | Ausgabe 1/2017 Open Access

A systematic review of diagnostic methods to differentiate acute lung injury/acute respiratory distress syndrome from cardiogenic pulmonary edema

Kosaku Komiya, Tomohiro Akaba, Yuji Kozaki, Jun-ichi Kadota, Bruce K. Rubin

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Markers of acute kidney injury in patients with sepsis: the role of soluble thrombomodulin

Shinshu Katayama, Shin Nunomiya, Kansuke Koyama, Masahiko Wada, Toshitaka Koinuma, Yuya Goto, Ken Tonai, Jun Shima

01.12.2017 | Editorial | Ausgabe 1/2017 Open Access

Immunosuppression and herpes viral reactivation in intensive care unit patients: one size does not fit all

Julien Textoris, François Mallet

01.12.2017 | Letter | Ausgabe 1/2017 Open Access

Renal replacement therapy after cardiac surgery: do not ask “When”, ask “Why”

Stéphane Gaudry, David Hajage, Didier Dreyfuss

01.12.2017 | Letter | Ausgabe 1/2017 Open Access

Hydrolysed protein enteral nutrition is not superior to polymeric whole protein feeding with regard to gastrointestinal feeding tolerance and feeding adequacy

Arthur R. H. van Zanten, Gunnar Elke

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Variation in monitoring and treatment policies for intracranial hypertension in traumatic brain injury: a survey in 66 neurotrauma centers participating in the CENTER-TBI study

Maryse C. Cnossen, Jilske A. Huijben, Mathieu van der Jagt, Victor Volovici, Thomas van Essen, Suzanne Polinder, David Nelson, Ari Ercole, Nino Stocchetti, Giuseppe Citerio, Wilco C. Peul, Andrew I. R. Maas, David Menon, Ewout W. Steyerberg, Hester F. Lingsma, on behalf of the CENTER-TBI investigators

01.12.2017 | Research | Ausgabe 1/2017 Open Access

A pilot clinical trial of recombinant human angiotensin-converting enzyme 2 in acute respiratory distress syndrome

Akram Khan, Cody Benthin, Brian Zeno, Timothy E. Albertson, John Boyd, Jason D. Christie, Richard Hall, Germain Poirier, Juan J. Ronco, Mark Tidswell, Kelly Hardes, William M. Powley, Tracey J. Wright, Sarah K. Siederer, David A. Fairman, David A. Lipson, Andrew I. Bayliffe, Aili L. Lazaar

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Loxapine to control agitation during weaning from mechanical ventilation

Stéphane Gaudry, Benjamin Sztrymf, Romain Sonneville, Bruno Megarbane, Guillaume Van Der Meersch, Dominique Vodovar, Yves Cohen, Jean-Damien Ricard, David Hajage, Laurence Salomon, Didier Dreyfuss

01.12.2017 | Letter | Ausgabe 1/2017 Open Access

Targeted therapeutic mild hypercapnia after cardiac arrest: a part of the bundle of care for mitigating secondary injury after cardiac arrest

Romain Jouffroy, Benoît Vivien

01.12.2017 | Editorial | Ausgabe 1/2017 Open Access

Traversing the valley of glycemic control despair

J. Geoffrey Chase, Jennifer L. Dickson

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Prognostic value of platelet-to-lymphocyte ratios among critically ill patients with acute kidney injury

Chen-Fei Zheng, Wen-Yue Liu, Fang-Fang Zeng, Ming-Hua Zheng, Hong-Ying Shi, Ying Zhou, Jing-Ye Pan

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Satisfaction with quality of ICU care for patients and families: the euroQ2 project

Hanne Irene Jensen, Rik T. Gerritsen, Matty Koopmans, Lois Downey, Ruth A. Engelberg, J. Randall Curtis, Peter E. Spronk, Jan G. Zijlstra, Helle Ørding

01.12.2017 | Review | Ausgabe 1/2017 Open Access

Respiratory support in patients with acute respiratory distress syndrome: an expert opinion

Davide Chiumello, Laurent Brochard, John J. Marini, Arthur S. Slutsky, Jordi Mancebo, V. Marco Ranieri, B. Taylor Thompson, Laurent Papazian, Marcus J. Schultz, Marcelo Amato, Luciano Gattinoni, Alain Mercat, Antonio Pesenti, Daniel Talmor, Jean-Louis Vincent

01.12.2017 | Letter | Ausgabe 1/2017 Open Access

Accounting for single center effects in systematic reviews cannot be overlooked

Bruno Adler Maccagnan Pinheiro Besen, Marcelo Park, Antonio Paulo Nassar Jr

01.12.2017 | Letter | Ausgabe 1/2017 Open Access

Main limitations of transpulmonary thermodilution: set targets

Manuel Sánchez-Sánchez, Eva Herrero, Lucia Cachafeiro, Eva Flores, Alexander Agrifoglio, Belén Civantos, Abelardo García-de-Lorenzo

01.12.2017 | Letter | Ausgabe 1/2017 Open Access

Effect of extended visiting hours on physician distractions in the ICU: a before-and-after study

Kay Choong See, Xie Ying Song, Han Tun Aung

01.12.2017 | Letter | Ausgabe 1/2017 Open Access

Limited evidence to recommend against open chest cardiopulmonary resuscitation in blunt trauma

Stefano Malinverni, Pierre Mols

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Undetectable haptoglobin is associated with major adverse kidney events in critically ill burn patients

François Dépret, Chloé Dunyach, Christian De Tymowski, Maïté Chaussard, Aurélien Bataille, Axelle Ferry, Nabila Moreno, Alexandru Cupaciu, Sabri Soussi, Mourad Benyamina, Alexandre Mebazaa, Kevin Serror, Marc Chaouat, Jean-Pierre Garnier, Romain Pirracchio, Matthieu Legrand, for the PRONOBURN group

01.12.2017 | Letter | Ausgabe 1/2017 Open Access

Pre-emptive and therapeutic value of blocking bacterial attachment to the endothelial alphaVbeta3 integrin with cilengitide in sepsis

Carolina D. Garciarena, Tony M. McHale, Ignacio Martin-Loeches, Steve W. Kerrigan

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Systemic impact on secondary brain aggravation due to ischemia/reperfusion injury in post-cardiac arrest syndrome: a prospective observational study using high-mobility group box 1 protein

Atsunori Sugita, Kosaku Kinoshita, Atsushi Sakurai, Nobutaka Chiba, Junko Yamaguchi, Tsukasa Kuwana, Nami Sawada, Satoshi Hori

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Blind bedside postpyloric placement of spiral tube as rescue therapy in critically ill patients: a prospective, tricentric, observational study

Bo Lv, Linhui Hu, Lifang Chen, Bei Hu, Yanlin Zhang, Heng Ye, Cheng Sun, Xiunong Zhang, Huilan Lan, Chunbo Chen

01.12.2017 | Viewpoint | Ausgabe 1/2017 Open Access

Evaluating physical functioning in critical care: considerations for clinical practice and research

Selina M. Parry, Minxuan Huang, Dale M. Needham

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Simplified prognostic model for critically ill patients in resource limited settings in South Asia

Rashan Haniffa, Mavuto Mukaka, Sithum Bandara Munasinghe, Ambepitiyawaduge Pubudu De Silva, Kosala Saroj Amarasiri Jayasinghe, Abi Beane, Nicolette de Keizer, Arjen M. Dondorp

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Association between kidney intracapsular pressure and ultrasound elastography

Kianoush B. Kashani, Shennen A. Mao, Sami Safadi, Bruce P. Amiot, Jaime M. Glorioso, John C. Lieske, Scott L. Nyberg, Xiaoming Zhang

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Levosimendan for patients with severely reduced left ventricular systolic function and/or low cardiac output syndrome undergoing cardiac surgery: a systematic review and meta-analysis

Filippo Sanfilippo, Joshua B. Knight, Sabino Scolletta, Cristina Santonocito, Federico Pastore, Ferdinando L. Lorini, Luigi Tritapepe, Andrea Morelli, Antonio Arcadipane

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Effect of levosimendan on prognosis in adult patients undergoing cardiac surgery: a meta-analysis of randomized controlled trials

Qi-Hong Chen, Rui-Qiang Zheng, Hua Lin, Jun Shao, Jiang-quan Yu, Hua-Ling Wang

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Predictors of diffuse alveolar damage in patients with acute respiratory distress syndrome: a retrospective analysis of clinical autopsies

Arnaud W. Thille, Oscar Peñuelas, José A. Lorente, Pilar Fernández-Segoviano, José-Maria Rodriguez, José-Antonio Aramburu, Julian Panizo, Andres Esteban, Fernando Frutos-Vivar

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Mildly elevated lactate levels are associated with microcirculatory flow abnormalities and increased mortality: a microSOAP post hoc analysis

Namkje A. R. Vellinga, E. Christiaan Boerma, Matty Koopmans, Abele Donati, Arnaldo Dubin, Nathan I. Shapiro, Rupert M. Pearse, Peter H. J. van der Voort, Arjen M. Dondorp, Tony Bafi, Michael Fries, Tulin Akarsu-Ayazoglu, Andrius Pranskunas, Steven Hollenberg, Gianmarco Balestra, Mat van Iterson, Farid Sadaka, Gary Minto, Ulku Aypar, F. Javier Hurtado, Giampaolo Martinelli, Didier Payen, Frank van Haren, Anthony Holley, Hernando Gomez, Ravindra L. Mehta, Alejandro H. Rodriguez, Carolina Ruiz, Héctor S. Canales, Jacques Duranteau, Peter E. Spronk, Shaman Jhanji, Sheena Hubble, Marialuisa Chierego, Christian Jung, Daniel Martin, Carlo Sorbara, Jan Bakker, Can Ince, for the microSOAP study group

01.12.2017 | Erratum | Ausgabe 1/2017 Open Access

Erratum to: Immunomodulation after ischemic stroke: potential mechanisms and implications for therapy

Cynthia Santos Samary, Paolo Pelosi, Pedro Leme Silva, Patricia Rieken Macedo Rocco

01.12.2017 | Review | Ausgabe 1/2017 Open Access

Precision medicine for all? Challenges and opportunities for a precision medicine approach to critical illness

Christopher W. Seymour, Hernando Gomez, Chung-Chou H. Chang, Gilles Clermont, John A. Kellum, Jason Kennedy, Sachin Yende, Derek C. Angus

01.12.2017 | Letter | Ausgabe 1/2017 Open Access

Finding the precision to improve outcome in patients after cardiac arrest

Gentle Sunder Shrestha

01.12.2017 | Viewpoint | Ausgabe 1/2017 Open Access

Individualized perfusion targets in hypoxic ischemic brain injury after cardiac arrest

Mypinder S. Sekhon, Donald E. Griesdale

01.12.2017 | Review | Ausgabe 1/2017 Open Access

Sleeping with the enemy: Clostridium difficile infection in the intensive care unit

Florian Prechter, Katrin Katzer, Michael Bauer, Andreas Stallmach

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Three-dimensional ultrastructure of capillary endothelial glycocalyx under normal and experimental endotoxemic conditions

Hideshi Okada, Genzou Takemura, Kodai Suzuki, Kazumasa Oda, Chihiro Takada, Yasuaki Hotta, Nagisa Miyazaki, Akiko Tsujimoto, Isamu Muraki, Yoshiaki Ando, Ryogen Zaikokuji, Atsumu Matsumoto, Hiroki Kitagaki, Yuto Tamaoki, Takahiro Usui, Tomoaki Doi, Takahiro Yoshida, Shozo Yoshida, Hiroaki Ushikoshi, Izumi Toyoda, Shinji Ogura

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Translational evidence for two distinct patterns of neuroaxonal injury in sepsis: a longitudinal, prospective translational study

Johannes Ehler, Lucinda K. Barrett, Valerie Taylor, Michael Groves, Francesco Scaravilli, Matthias Wittstock, Stephan Kolbaske, Annette Grossmann, Jörg Henschel, Martin Gloger, Tarek Sharshar, Fabrice Chretien, Francoise Gray, Gabriele Nöldge-Schomburg, Mervyn Singer, Martin Sauer, Axel Petzold

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Role of renal function in risk assessment of target non-attainment after standard dosing of meropenem in critically ill patients: a prospective observational study

Lisa Ehmann, Michael Zoller, Iris K. Minichmayr, Christina Scharf, Barbara Maier, Maximilian V. Schmitt, Niklas Hartung, Wilhelm Huisinga, Michael Vogeser, Lorenz Frey, Johannes Zander, Charlotte Kloft

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Aerosol delivery during invasive mechanical ventilation: a systematic review

Jonathan Dugernier, Stephan Ehrmann, Thierry Sottiaux, Jean Roeseler, Xavier Wittebole, Thierry Dugernier, François Jamar, Pierre-François Laterre, Gregory Reychler

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Functional evaluation of sublingual microcirculation indicates successful weaning from VA-ECMO in cardiogenic shock

Sakir Akin, Dinis dos Reis Miranda, Kadir Caliskan, Osama I. Soliman, Goksel Guven, Ard Struijs, Robert J. van Thiel, Lucia S. Jewbali, Alexandre Lima, Diederik Gommers, Felix Zijlstra, Can Ince

01.12.2017 | Letter | Ausgabe 1/2017 Open Access

Noninvasive ventilation in hypercapnic chronic obstructive pulmonary disease

Silvio A. Ñamendys-Silva

01.12.2017 | Letter | Ausgabe 1/2017 Open Access

Lactate and stepwise lactate kinetics can be used to guide resuscitation

Xiang Zhou, Dawei Liu, Longxiang Su

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Implementation of sepsis bundles in public hospitals in Brazil: a prospective study with heterogeneous results

Flavia Ribeiro Machado, Elaine Maria Ferreira, Pierre Schippers, Ilusca Cardoso de Paula, Letícia Sandre Vendrame Saes, Francisco Ivanildo de Oliveira Jr, Paula Tuma, Wilson Nogueira Filho, Felipe Piza, Sandra Guare, Cláudia Mangini, Gustavo Ziggiatti Guth, Luciano Cesar Pontes Azevedo, Flavio Geraldo Resende Freitas, Jose Luiz Gomes do Amaral, Nacime Salomão Mansur, Reinaldo Salomão, on behalf of the SPDM against sepsis project

01.12.2017 | Research | Ausgabe 1/2017 Open Access

The impact of N-acetylcysteine and ascorbic acid in contrast-induced nephropathy in critical care patients: an open-label randomized controlled study

Eleni Palli, Demosthenes Makris, John Papanikolaou, Grigorios Garoufalis, Irini Tsilioni, Paris Zygoulis, Epaminondas Zakynthinos

01.12.2017 | Letter | Ausgabe 1/2017 Open Access

Does enhanced antibiotic de-escalation really have no benefit in the ICU?

Shingo Ohki, Shinichiro Ohshimo, Nobuaki Shime

01.12.2017 | Letter | Ausgabe 1/2017 Open Access

Icatibant as an early rescue therapy in hypovolemic shock with converting enzyme inhibitor treatment

Hélène Charbonneau, Marie Buléon, Benoit Richard, Nicolas Mayeur

01.12.2017 | Research | Ausgabe 1/2017 Open Access

The impact of sex and age on neurological outcomes in out-of-hospital cardiac arrest patients with targeted temperature management

Sang Hoon Oh, Kyu Nam Park, Jeeyong Lim, Seung Pill Choi, Joo Suk Oh, In Soo Cho, Byung Kook Lee, Yong Hwan Kim, Young-Min Kim, Han Joon Kim, Chun Song Youn, Soo Hyun Kim, On behalf of the Korean Hypothermia Network Investigators

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Early psychological screening of intensive care unit survivors: a prospective cohort study

Anna Milton, Emily Brück, Anna Schandl, Matteo Bottai, Peter Sackey

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Vasculotide reduces pulmonary hyperpermeability in experimental pneumococcal pneumonia

Birgitt Gutbier, Xiaohui Jiang, Kristina Dietert, Carolin Ehrler, Jasmin Lienau, Paul Van Slyke, Harold Kim, Van C. Hoang, Jason T. Maynes, Daniel J. Dumont, Achim D. Gruber, Norbert Weissmann, Timothy J. Mitchell, Norbert Suttorp, Martin Witzenrath

01.12.2017 | Editorial | Ausgabe 1/2017 Open Access

An isolated elevation in blood urea level is not ‘uraemia’ and not an indication for renal replacement therapy in the ICU

Jack Mackenzie, Bobby Chacko

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Cefepime-induced neurotoxicity: a systematic review

Lauren E. Payne, David J. Gagnon, Richard R. Riker, David B. Seder, Elizabeth K. Glisic, Jane G. Morris, Gilles L. Fraser

01.12.2017 | Letter | Ausgabe 1/2017 Open Access

Angiotensin II in vasodilatory shock: lights and shadows

Elio Antonucci, Sara Agosta, Yasser Sakr

01.12.2017 | Letter | Ausgabe 1/2017 Open Access

Weekend effect: a great problem with a potential solution

Ana Abella, Beatriz Lobo-Valbuena, Marcela Hómez, Federico Gordo

01.12.2017 | Review | Ausgabe 1/2017 Open Access

Pearls and pitfalls in comprehensive critical care echocardiography

Sam Orde, Michel Slama, Andrew Hilton, Konstantin Yastrebov, Anthony McLean

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Kinetic estimated glomerular filtration rate in critically ill patients: beyond the acute kidney injury severity classification system

Flávio de Oliveira Marques, Saulo Aires Oliveira, Priscila Ferreira de Lima e Souza, Wandervânia Gomes Nojoza, Maiara da Silva Sena, Taynara Muniz Ferreira, Bruno Gabriele Costa, Alexandre Braga Libório

01.12.2017 | Viewpoint | Ausgabe 1/2017 Open Access

Complications of regional citrate anticoagulation: accumulation or overload?

Antoine G. Schneider, Didier Journois, Thomas Rimmelé

01.12.2017 | Research | Ausgabe 1/2017 Open Access

A clinical prediction model to identify patients at high risk of hemodynamic instability in the pediatric intensive care unit

Cristhian Potes, Bryan Conroy, Minnan Xu-Wilson, Christopher Newth, David Inwald, Joseph Frassica

01.12.2017 | Editorial | Ausgabe 1/2017 Open Access

Identifying “at-risk” patients for sub-optimal beta-lactam exposure in critically ill patients with severe infections

Mohd H. Abdul-Aziz, Jeffrey Lipman, Jason A. Roberts

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Impact of earplugs and eye mask on sleep in critically ill patients: a prospective randomized study

Alexandre Demoule, Serge Carreira, Sophie Lavault, Olivier Pallanca, Elise Morawiec, Julien Mayaux, Isabelle Arnulf, Thomas Similowski

01.12.2017 | Letter | Ausgabe 1/2017 Open Access

High-flow nasal cannula versus noninvasive positive pressure ventilation in acute respiratory failure: interaction between PaO2/FiO2 and tidal volume

Yanfei Shen, Weimin Zhang

01.12.2017 | Editorial | Ausgabe 1/2017 Open Access

Age, exercise, and the outcome of sepsis

Debasree Banerjee, Steven M. Opal

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Vitamin D deficiency in critically ill children: a systematic review and meta-analysis

James Dayre McNally, Nassr Nama, Katie O’Hearn, Margaret Sampson, Karin Amrein, Klevis Iliriani, Lauralyn McIntyre, Dean Fergusson, Kusum Menon

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Video laryngoscopy does not improve the intubation outcomes in emergency and critical patients – a systematic review and meta-analysis of randomized controlled trials

Jia Jiang, Danxu Ma, Bo Li, Yun Yue, Fushan Xue

01.12.2017 | Research | Ausgabe 1/2017 Open Access

High-volume hemofiltration in adult burn patients with septic shock and acute kidney injury: a multicenter randomized controlled trial

Kevin K. Chung, Elsa C. Coates, David J. Smith Jr, Rachel A. Karlnoski, William L. Hickerson, Angela L. Arnold-Ross, Michael J. Mosier, Marcia Halerz, Amy M. Sprague, Robert F. Mullins, Daniel M. Caruso, Marlene Albrecht, Brett D. Arnoldo, Agnes M. Burris, Sandra L. Taylor, Steven E. Wolf, for the Randomized controlled Evaluation of high-volume hemofiltration in adult burn patients with Septic shoCk and acUte kidnEy injury (RESCUE) Investigators

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Chloral hydrate enteral infusion for sedation in ventilated children: the CHOSEN pilot study

Ari R. Joffe, Jessica Hogan, Cathy Sheppard, Gerda Tawfik, Jonathan P. Duff, Gonzalo Garcia Guerra

01.12.2017 | Editorial | Ausgabe 1/2017 Open Access

Iatrogenic hemodilution: a possible cause for avoidable blood transfusions?

Azriel Perel

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Longitudinal wall fractional shortening: an M-mode index based on mitral annular plane systolic excursion (MAPSE) that correlates and predicts left ventricular longitudinal strain (LVLS) in intensive care patients

Stephen J. Huang, Iris Ting, Andrea M. Huang, Michel Slama, Anthony S. McLean

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Initial nutritional management during noninvasive ventilation and outcomes: a retrospective cohort study

Nicolas Terzi, Michael Darmon, Jean Reignier, Stéphane Ruckly, Maïté Garrouste-Orgeas, Alexandre Lautrette, Elie Azoulay, Bruno Mourvillier, Laurent Argaud, Laurent Papazian, Marc Gainnier, Dan Goldgran-Toledano, Samir Jamali, Anne-Sylvie Dumenil, Carole Schwebel, Jean-François Timsit, for the OUTCOMEREA study group

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Long-term continuous renal replacement therapy and anticoagulation with citrate in critically ill patients with severe liver dysfunction

Matthias Klingele, Theresa Stadler, Danilo Fliser, Timo Speer, Heinrich V. Groesdonk, Alexander Raddatz

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Change in cardiac output during Trendelenburg maneuver is a reliable predictor of fluid responsiveness in patients with acute respiratory distress syndrome in the prone position under protective ventilation

Hodane Yonis, Laurent Bitker, Mylène Aublanc, Sophie Perinel Ragey, Zakaria Riad, Floriane Lissonde, Aurore Louf-Durier, Sophie Debord, Florent Gobert, Romain Tapponnier, Claude Guérin, Jean-Christophe Richard

01.12.2017 | Review | Ausgabe 1/2017 Open Access

Recovery after critical illness: putting the puzzle together—a consensus of 29

Elie Azoulay, Jean-Louis Vincent, Derek C. Angus, Yaseen M. Arabi, Laurent Brochard, Stephen J. Brett, Giuseppe Citerio, Deborah J. Cook, Jared Randall Curtis, Claudia C. dos Santos, E. Wesley Ely, Jesse Hall, Scott D. Halpern, Nicholas Hart, Ramona O. Hopkins, Theodore J. Iwashyna, Samir Jaber, Nicola Latronico, Sangeeta Mehta, Dale M. Needham, Judith Nelson, Kathleen Puntillo, Michael Quintel, Kathy Rowan, Gordon Rubenfeld, Greet Van den Berghe, Johannes Van der Hoeven, Hannah Wunsch, Margaret Herridge

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Extracorporeal membrane oxygenation for life-threatening asthma refractory to mechanical ventilation: analysis of the Extracorporeal Life Support Organization registry

Hye Ju Yeo, Dohyung Kim, Doosoo Jeon, Yun Seong Kim, Peter Rycus, Woo Hyun Cho

01.12.2017 | Research | Ausgabe 1/2017 Open Access

A supplemental intravenous amino acid infusion sustains a positive protein balance for 24 hours in critically ill patients

Martin Sundström Rehal, Felix Liebau, Inga Tjäder, Åke Norberg, Olav Rooyackers, Jan Wernerman

01.12.2017 | Letter | Ausgabe 1/2017 Open Access

A systematic approach to ultrasound-guided central venous catheter placement—desirable modifications

Ryszard Gawda, Tomasz Czarnik

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Hypovitaminosis C and vitamin C deficiency in critically ill patients despite recommended enteral and parenteral intakes

Anitra C. Carr, Patrice C. Rosengrave, Simone Bayer, Steve Chambers, Jan Mehrtens, Geoff M. Shaw

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Comparison of mortality prediction models in acute respiratory distress syndrome undergoing extracorporeal membrane oxygenation and development of a novel prediction score: the PREdiction of Survival on ECMO Therapy-Score (PRESET-Score)

Michael Hilder, Frank Herbstreit, Michael Adamzik, Martin Beiderlinden, Markus Bürschen, Jürgen Peters, Ulrich H. Frey

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Microvascular effects of intravenous esmolol in patients with normal cardiac function undergoing postoperative atrial fibrillation: a prospective pilot study in cardiothoracic surgery

William Fornier, Matthias Jacquet-Lagrèze, Thomas Collenot, Priscilla Teixeira, Philippe Portran, Rémi Schweizer, Michel Ovize, Jean-Luc Fellahi

01.12.2017 | Letter | Ausgabe 1/2017 Open Access

The term “supplemental parenteral nutrition” should be restricted to studies meeting specific technical criteria

Claude Pichard, Mette M. Berger

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Hyaluronic acid is associated with organ dysfunction in acute respiratory distress syndrome

Anthony J. Esposito, Pavan K. Bhatraju, Renee D. Stapleton, Mark M. Wurfel, Carmen Mikacenic

01.12.2017 | Editorial | Ausgabe 1/2017 Open Access

Recombinant human ACE2: acing out angiotensin II in ARDS therapy

Haibo Zhang, Andrew Baker

01.12.2017 | Letter | Ausgabe 1/2017 Open Access

The forgotten value of the clinical examination to individualize and guide fluid resuscitation in patients with sepsis

Gentle Sunder Shrestha, Martin Dünser, Mervyn Mer

01.12.2017 | Letter | Ausgabe 1/2017 Open Access

Necessary additional steps in ultrasound guided central venous catheter placement: getting to the heart of the matter

Thei S. Steenvoorden, Jasper M. Smit, Mark E. Haaksma, Pieter R. Tuinman

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Co-administration of vancomycin and piperacillin-tazobactam is associated with increased renal dysfunction in adult and pediatric burn patients

Gabriel Hundeshagen, David N. Herndon, Karel D. Capek, Ludwik K. Branski, Charles D. Voigt, Elizabeth A. Killion, Janos Cambiaso-Daniel, Michaela Sljivich, Andrew De Crescenzo, Ronald P. Mlcak, Michael P. Kinsky, Celeste C. Finnerty, William B. Norbury

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Antimicrobials for the treatment of drug-resistant Acinetobacter baumannii pneumonia in critically ill patients: a systemic review and Bayesian network meta-analysis

Su Young Jung, Seung Hee Lee, Soo Young Lee, Seungwon Yang, Hayeon Noh, Eun Kyoung Chung, Jangik I. Lee

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Comparison of the efficacy of three topical antiseptic solutions for the prevention of catheter colonization: a multicenter randomized controlled study

Hideto Yasuda, Masamitsu Sanui, Takayuki Abe, Nobuaki Shime, Tetsuya Komuro, Junji Hatakeyama, Shohei Matsukubo, Shinji Kawano, Hiroshi Yamamoto, Kohkichi Andoh, Ryutaro Seo, Kyo Inoue, Eiichiro Noda, Nobuyuki Saito, Satoshi Nogami, Kentaro Okamoto, Ryota Fuke, Yasuhiro Gushima, Atsuko Kobayashi, Toru Takebayashi, Alan Kawarai Lefor, for Japanese Society of Education for Physicians and Trainees in Intensive Care (JSEPTIC) Clinical Trial Group

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Copeptin in acute decompensation of liver cirrhosis: relationship with acute-on-chronic liver failure and short-term survival

Annarein J. C. Kerbert, Hein W. Verspaget, Àlex Amorós Navarro, Rajiv Jalan, Elsa Solà, Daniel Benten, François Durand, Pere Ginès, Johan J. van der Reijden, Bart van Hoek, Minneke J. Coenraad, for the CANONIC Study Investigators of the EASL-CLIF Consortium

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Initial blood pH during cardiopulmonary resuscitation in out-of-hospital cardiac arrest patients: a multicenter observational registry-based study

Jonghwan Shin, Yong Su Lim, Kyuseok Kim, Hui Jai Lee, Se Jong Lee, Euigi Jung, Kyoung Min You, Hyuk Jun Yang, Jin Joo Kim, Joonghee Kim, You Hwan Jo, Jae Hyuk Lee, Seong Youn Hwang

01.12.2017 | Letter | Ausgabe 1/2017 Open Access

Subclavian oblique-axis catheterization technique

Alessandro De Cassai, Helmut Galligioni

01.12.2017 | Research | Ausgabe 1/2017 Open Access

The effect of angiotensin II on blood pressure in patients with circulatory shock: a structured review of the literature

Laurence W. Busse, Michael T. McCurdy, Osman Ali, Anna Hall, Huaizhen Chen, Marlies Ostermann

01.12.2017 | Review | Ausgabe 1/2017 Open Access

Thoracic ultrasound for pleural effusion in the intensive care unit: a narrative review from diagnosis to treatment

E. Brogi, L. Gargani, E. Bignami, F. Barbariol, A. Marra, F. Forfori, L. Vetrugno

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Timing of renal replacement therapy and long-term risk of chronic kidney disease and death in intensive care patients with acute kidney injury

Søren Christiansen, Steffen Christensen, Lars Pedersen, Henrik Gammelager, J. Bradley Layton, M. Alan Brookhart, Christian Fynbo Christiansen

01.12.2017 | Letter | Ausgabe 1/2017 Open Access

Do we know enough to recommend corticosteroids in acute respiratory distress syndrome?

Mathieu Blot, Arnaud Salmon-Rousseau, Pascal Chavanet, Lionel Piroth

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Association between continuous hyperosmolar therapy and survival in patients with traumatic brain injury – a multicentre prospective cohort study and systematic review

Karim Asehnoune, Sigismond Lasocki, Philippe Seguin, Thomas Geeraerts, Pierre François Perrigault, Claire Dahyot-Fizelier, Catherine Paugam Burtz, Fabrice Cook, Dominique Demeure dit latte, Raphael Cinotti, Pierre Joachim Mahe, Camille Fortuit, Romain Pirracchio, Fanny Feuillet, Véronique Sébille, Antoine Roquilly, For the ATLANREA group, For the COBI group

01.12.2017 | Letter | Ausgabe 1/2017 Open Access

The evolving role of the renin–angiotensin system in ARDS

Eleni Vrigkou, Iraklis Tsangaris, Stefanos Bonovas, Argyrios Tsantes, Petros Kopterides

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Bronchoscopy versus an endotracheal tube mounted camera for the peri-interventional visualization of percutaneous dilatational tracheostomy - a prospective, randomized trial (VivaPDT)

Jörn Grensemann, Lars Eichler, Sophie Kähler, Dominik Jarczak, Marcel Simon, Hans O. Pinnschmidt, Stefan Kluge

01.12.2017 | Letter | Ausgabe 1/2017 Open Access

Ultrasound-guided central venous catheter placement: first things first

Bernd Saugel, Leonie Schulte-Uentrop, Thomas W. L. Scheeren, Jean-Louis Teboul

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