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Zeitschrift

Critical Care

Critical Care 1/2019

Ausgabe 1/2019

Inhaltsverzeichnis ( 338 Artikel )

01.12.2019 | Research | Ausgabe 1/2019 Open Access

Improvement in the survival rates of extracorporeal membrane oxygenation-supported respiratory failure patients: a multicenter retrospective study in Korean patients

Moon Seong Baek, Sang-Min Lee, Chi Ryang Chung, Woo Hyun Cho, Young-Jae Cho, Sunghoon Park, So-My Koo, Jae-Seung Jung, Seung Yong Park, Youjin Chang, Byung Ju Kang, Jung-Hyun Kim, Jin Young Oh, So Hee Park, Jung-Wan Yoo, Yun Su Sim, Sang-Bum Hong

01.12.2019 | Research | Ausgabe 1/2019 Open Access

Neurally adjusted ventilatory assist (NAVA) versus pressure support ventilation: patient-ventilator interaction during invasive ventilation delivered by tracheostomy

Olivier Lamouret, Laure Crognier, Fanny Vardon Bounes, Jean-Marie Conil, Caroline Dilasser, Thibaut Raimondi, Stephanie Ruiz, Antoine Rouget, Clément Delmas, Thierry Seguin, Vincent Minville, Bernard Georges

01.12.2019 | Research | Ausgabe 1/2019 Open Access

Enteral versus intravenous approach for the sedation of critically ill patients: a randomized and controlled trial

Giovanni Mistraletti, Michele Umbrello, Silvia Salini, Paolo Cadringher, Paolo Formenti, Davide Chiumello, Cristina Villa, Riccarda Russo, Silvia Francesconi, Federico Valdambrini, Giacomo Bellani, Alessandra Palo, Francesca Riccardi, Enrica Ferretti, Maurilio Festa, Anna Maria Gado, Martina Taverna, Cristina Pinna, Alessandro Barbiero, Pier Alda Ferrari, Gaetano Iapichino, the SedaEN investigators

01.12.2019 | Letter | Ausgabe 1/2019 Open Access

Optimal pressing strength and time for capillary refilling time

Rui Kawaguchi, Taka-aki Nakada, Taku Oshima, Masayoshi Shinozaki, Toshiya Nakaguchi, Hideaki Haneishi, Shigeto Oda

01.12.2019 | Letter | Ausgabe 1/2019 Open Access

Dosing adjuvant vitamin C in critically ill patients undergoing continuous renal replacement therapy: We are not there yet!

Patrick M. Honore, David De Bels, Luc Kugener, Sebastien Redant, Rachid Attou, Andrea Gallerani, Herbert D. Spapen

01.12.2019 | Letter | Ausgabe 1/2019 Open Access

Intact cerebrovascular autoregulation in patients with refractory status epilepticus due to sufficient anesthetic treatment on a neurointensive care unit: a prospective cohort study

Marco Meyer, Martin Juenemann, Tobias Braun, Ingo Schirotzek, Patrick Schramm

01.12.2019 | Editorial | Ausgabe 1/2019 Open Access

Artificial intelligence in the intensive care unit

Christopher A. Lovejoy, Varun Buch, Mahiben Maruthappu

01.12.2019 | Letter | Ausgabe 1/2019 Open Access

A conceivable mechanism of harm in a stretched “teen lung”

João Batista Borges

01.12.2019 | Research | Ausgabe 1/2019 Open Access

Early diuretic use and mortality in critically ill patients with vasopressor support: a propensity score-matching analysis

Yanfei Shen, Weimin Zhang, Yong Shen

01.12.2019 | Letter | Ausgabe 1/2019 Open Access

Hyperchloremia-associated acute chronic kidney injury: beware of confounders!

Patrick M. Honore, David De Bels, Luc Kugener, Sebastien Redant, Rachid Attou, Andrea Gallerani, Herbert D. Spapen

01.12.2019 | Research | Ausgabe 1/2019 Open Access

Predicting mortality in patients undergoing VA-ECMO after coronary artery bypass grafting: the REMEMBER score

Liangshan Wang, Feng Yang, Xiaomeng Wang, Haixiu Xie, Eddy Fan, Mark Ogino, Daniel Brodie, Hong Wang, Xiaotong Hou

01.12.2019 | Research Article | Ausgabe 1/2019 Open Access

Outcomes used in randomised controlled trials of nutrition in the critically ill: a systematic review

Garry Taverny, Thomas Lescot, Emmanuel Pardo, Frederique Thonon, Manar Maarouf, Corinne Alberti

01.12.2019 | Letter | Ausgabe 1/2019 Open Access

Increased dosing regimens of piperacillin-tazobactam are needed to avoid subtherapeutic exposure in critically ill patients with augmented renal clearance

Thibaud Besnard, Cédric Carrié, Laurent Petit, Matthieu Biais

01.12.2019 | Letter | Ausgabe 1/2019 Open Access

To remove and replace—a role for plasma exchange in counterbalancing the host response in sepsis

S. David, K. Stahl

01.12.2019 | Letter | Ausgabe 1/2019 Open Access

Vancomycin pharmacokinetics in critically ill obese patients: can the clinician sit back and relax?

Patrick M. Honore, David De Bels, Luc Kugener, Sebastien Redant, Rachid Attou, Andrea Gallerani, Herbert D. Spapen

01.12.2019 | Review | Ausgabe 1/2019 Open Access

The glycocalyx: a novel diagnostic and therapeutic target in sepsis

Ryo Uchimido, Eric P. Schmidt, Nathan I. Shapiro

01.12.2019 | Letter | Ausgabe 1/2019 Open Access

Potential confounders for the effect of high-flow nasal cannula oxygen therapy

Satoshi Yamaga, Shinichiro Ohshimo, Nobuaki Shime

01.12.2019 | Research | Ausgabe 1/2019 Open Access

Vascular endothelial cadherin shedding is more severe in sepsis patients with severe acute kidney injury

Wen-Kuang Yu, J. Brennan McNeil, Nancy E. Wickersham, Ciara M. Shaver, Julie A. Bastarache, Lorraine B. Ware

01.12.2019 | Research | Ausgabe 1/2019 Open Access

The effects of passive leg raising may be detected by the plethysmographic oxygen saturation signal in critically ill patients

Alexandra Beurton, Jean-Louis Teboul, Francesco Gavelli, Filipe Andre Gonzalez, Valentina Girotto, Laura Galarza, Nadia Anguel, Christian Richard, Xavier Monnet

01.12.2019 | Letter | Ausgabe 1/2019 Open Access

How to understand real net ultrafiltration and its association with low blood pressure in critically ill patients with renal replacement therapy

Wei Li, Jinsong Zhang, Xufeng Chen

01.12.2019 | Letter | Ausgabe 1/2019 Open Access

Cerebrospinal fluid procalcitonin predicts Gram-negative bacterial meningitis in patients with empiric antibiotic pretreatment

Wen Li, Fang Yuan, Xiaolong Sun, Zhihan Zhao, Yaoyao Zhang, Wen Jiang

01.12.2019 | Research | Ausgabe 1/2019 Open Access

Safety and efficacy of regional citrate anticoagulation for continuous renal replacement therapy in liver failure patients: a systematic review and meta-analysis

Wei Zhang, Ming Bai, Yan Yu, Lu Li, Lijuan Zhao, Shiren Sun, Xiangmei Chen

01.12.2019 | Letter | Ausgabe 1/2019 Open Access

Bronchoalveolar lavage fluid dilution in ICU patients: what we should know and what we should do

Yuetian Yu, Chunyan Liu, Zhongheng Zhang, Hui Shen, Yujie Li, Liangjing Lu, Yuan Gao

01.12.2019 | Review | Ausgabe 1/2019 Open Access

The aftermath of acute kidney injury: a narrative review of long-term mortality and renal function

Gijs Fortrie, Hilde R. H. de Geus, Michiel G. H. Betjes

01.12.2019 | Letter | Ausgabe 1/2019 Open Access

A smartphone comes to the rescue during tracheostomy

Animesh Ray, Bharath, Sanjeev Sinha, Saurav Sekhar Paul

01.12.2019 | Research | Ausgabe 1/2019 Open Access

Host genetic variants in sepsis risk: a field synopsis and meta-analysis

Hongxiang Lu, Dalin Wen, Xu Wang, Lebin Gan, Juan Du, Jianhui Sun, Ling Zeng, Jianxin Jiang, Anqiang Zhang

01.12.2019 | Research | Ausgabe 1/2019 Open Access

Comparison of extracorporeal and conventional cardiopulmonary resuscitation: a retrospective propensity score matched study

Daniel Patricio, Lorenzo Peluso, Alexandre Brasseur, Olivier Lheureux, Mirko Belliato, Jean-Louis Vincent, Jacques Creteur, Fabio Silvio Taccone

01.12.2019 | Research | Ausgabe 1/2019 Open Access

The effect of diabetes on burn patients: a retrospective cohort study

Reinhard Dolp, Sarah Rehou, Ruxandra Pinto, Rachel Trister, Marc G. Jeschke

01.12.2019 | Letter | Ausgabe 1/2019 Open Access

The adrenal-vitamin C axis: from fish to guinea pigs and primates

Michael H. Hooper, Anitra Carr, Paul E. Marik

01.12.2019 | Research | Ausgabe 1/2019 Open Access

Associations between partial pressure of oxygen and neurological outcome in out-of-hospital cardiac arrest patients: an explorative analysis of a randomized trial

Florian Ebner, Susann Ullén, Anders Åneman, Tobias Cronberg, Niklas Mattsson, Hans Friberg, Christian Hassager, Jesper Kjærgaard, Michael Kuiper, Paolo Pelosi, Johan Undén, Matt P. Wise, Jørn Wetterslev, Niklas Nielsen

01.12.2019 | Research | Ausgabe 1/2019 Open Access

Sigh maneuver to enhance assessment of fluid responsiveness during pressure support ventilation

Antonio Messina, Davide Colombo, Federico Lorenzo Barra, Gianmaria Cammarota, Giacomo De Mattei, Federico Longhini, Stefano Romagnoli, Francesco DellaCorte, Daniel De Backer, Maurizio Cecconi, Paolo Navalesi

01.12.2019 | Editorial | Ausgabe 1/2019 Open Access

Humanizing the intensive care unit

Michael E. Wilson, Sarah Beesley, Amanda Grow, Eileen Rubin, Ramona O. Hopkins, Negin Hajizadeh, Samuel M. Brown

01.12.2019 | Editorial | Ausgabe 1/2019 Open Access

Electrophysiological investigations of peripheral nerves and muscles: a method for looking at cell dysfunction in the critically ill patients

Nicola Latronico, Oliver Friedrich

01.12.2019 | Research | Ausgabe 1/2019 Open Access

Organizational factors associated with target sedation on the first 48 h of mechanical ventilation: an analysis of checklist-ICU database

Antonio Paulo Nassar Jr, Fernando G. Zampieri, Jorge I. Salluh, Fernando A. Bozza, Flávia Ribeiro Machado, Helio Penna Guimarães, Lucas P. Damiani, Alexandre Biasi Cavalcanti

01.12.2019 | Letter | Ausgabe 1/2019 Open Access

Is fluid resuscitation the “Keyser Soze” of acute kidney injury in trauma patients?

Matthieu Jamme, Omar Ben Hadj Salem

01.12.2019 | Research | Ausgabe 1/2019 Open Access

The ELSO Maastricht Treaty for ECLS Nomenclature: abbreviations for cannulation configuration in extracorporeal life support - a position paper of the Extracorporeal Life Support Organization

Lars Mikael Broman, Fabio Silvio Taccone, Roberto Lorusso, Maximilian Valentin Malfertheiner, Federico Pappalardo, Matteo Di Nardo, Mirko Belliato, Melania M. Bembea, Ryan P. Barbaro, Rodrigo Diaz, Lorenzo Grazioli, Vincent Pellegrino, Malaika H. Mendonca, Daniel Brodie, Eddy Fan, Robert H. Bartlett, Michael M. McMullan, Steven A. Conrad

01.12.2019 | Letter | Ausgabe 1/2019 Open Access

Passive leg cycling and electrical stimulation cannot preserve strength in sepsis

Pierre-François Laterre, Cheryl Hickmann, Diego Castanares-Zapatero

01.12.2019 | Letter | Ausgabe 1/2019 Open Access

Letter on “Left ventricular systolic function evaluated by strain echocardiography and relationship with mortality in patients with severe sepsis or septic shock: a systematic review and meta-analysis”

Venu M. Velagapudi, Dennis A. Tighe

01.12.2019 | Research | Ausgabe 1/2019 Open Access

Impact of post-traumatic stress symptoms on the health-related quality of life in a cohort study with chronically critically ill patients and their partners: age matters

Gloria-Beatrice Wintermann, Katja Petrowski, Kerstin Weidner, Bernhard Strauß, Jenny Rosendahl

01.12.2019 | Research | Ausgabe 1/2019 Open Access

The early identification of disease progression in patients with suspected infection presenting to the emergency department: a multi-centre derivation and validation study

Kordo Saeed, Darius Cameron Wilson, Frank Bloos, Philipp Schuetz, Yuri van der Does, Olle Melander, Pierre Hausfater, Jacopo M. Legramante, Yann-Erick Claessens, Deveendra Amin, Mari Rosenqvist, Graham White, Beat Mueller, Maarten Limper, Carlota Clemente Callejo, Antonella Brandi, Marc-Alexis Macchi, Nicholas Cortes, Alexander Kutz, Peter Patka, María Cecilia Yañez, Sergio Bernardini, Nathalie Beau, Matthew Dryden, Eric C. M. van Gorp, Marilena Minieri, Louisa Chan, Pleunie P. M. Rood, Juan Gonzalez del Castillo

01.12.2019 | Research | Ausgabe 1/2019 Open Access

Low-dose atrial natriuretic peptide for prevention or treatment of acute kidney injury: a systematic review and meta-analysis

Hiroyuki Yamada, Kent Doi, Tatsuo Tsukamoto, Hideyasu Kiyomoto, Kazuto Yamashita, Motoko Yanagita, Yoshio Terada, Kiyoshi Mori

01.12.2019 | Research | Ausgabe 1/2019 Open Access

Thromboxane–prostaglandin receptor antagonist, terutroban, prevents neurovascular events after subarachnoid haemorrhage: a nanoSPECT study in rats

David Lagier, David Tonon, Philippe Garrigue, Benjamin Guillet, Laura Giacomino, Jean-Charles Martin, Marie-Christine Alessi, Nicolas Bruder, Lionel J. Velly

01.12.2019 | Research | Ausgabe 1/2019 Open Access

Lung fluid biomarkers for acute respiratory distress syndrome: a systematic review and meta-analysis

Yishan Wang, Huijuan Wang, Chunfang Zhang, Chao Zhang, Huqin Yang, Ruiyue Gao, Zhaohui Tong

01.12.2019 | Research | Ausgabe 1/2019 Open Access

Exosomes from endothelial progenitor cells improve outcomes of the lipopolysaccharide-induced acute lung injury

Yue Zhou, Pengfei Li, Andrew J. Goodwin, James A. Cook, Perry V. Halushka, Eugene Chang, Basilia Zingarelli, Hongkuan Fan

01.12.2019 | Research | Ausgabe 1/2019 Open Access

Cerebral metabolism is not affected by moderate hyperventilation in patients with traumatic brain injury

Giovanna Brandi, Nino Stocchetti, Alberto Pagnamenta, Federica Stretti, Peter Steiger, Stephanie Klinzing

01.12.2019 | Editorial | Ausgabe 1/2019 Open Access

Current place of probiotics for VAP

Harjeet Singh Virk, W. Joost Wiersinga

01.12.2019 | Editorial | Ausgabe 1/2019 Open Access

Predicting clinical outcome in patients undergoing VA-ECMO

Antoine Kimmoun, Bruno Levy

01.12.2019 | Letter | Ausgabe 1/2019 Open Access

NephroCheck: should we consider urine osmolality?

Alberto Noto, Andrea Cortegiani, Antonio David

01.12.2019 | Letter | Ausgabe 1/2019 Open Access

Assessment of intestinal perfusion by a new balloon-tipped transpyloric probe

Samir G. Sakka

01.12.2019 | Research | Ausgabe 1/2019 Open Access

Association of preadmission metformin use and mortality in patients with sepsis and diabetes mellitus: a systematic review and meta-analysis of cohort studies

Huoyan Liang, Xianfei Ding, Lifeng Li, Tian Wang, Quancheng Kan, Lexin Wang, Tongwen Sun

01.12.2019 | Research | Ausgabe 1/2019 Open Access

Invasive and non-invasive diagnostic approaches for microbiological diagnosis of hospital-acquired pneumonia

Otavio T. Ranzani, Tarek Senussi, Francesco Idone, Adrian Ceccato, Gianluigi Li Bassi, Miquel Ferrer, Antoni Torres

01.12.2019 | Research | Ausgabe 1/2019 Open Access

The clinical impacts and risk factors for non-central line-associated bloodstream infection in 5046 intensive care unit patients: an observational study based on electronic medical records

Shichao Zhu, Yan Kang, Wen Wang, Lin Cai, Xin Sun, Zhiyong Zong

01.12.2019 | Editorial | Ausgabe 1/2019 Open Access

Designing nutrition-based interventional trials for the future: addressing the known knowns

Danielle E. Bear, Zudin A. Puthucheary

01.12.2019 | Editorial | Ausgabe 1/2019 Open Access

The role of impaired brain perfusion in septic encephalopathy

Lucia Rivera-Lara

01.12.2019 | Letter | Ausgabe 1/2019 Open Access

Impact of acute renal failure on plasmatic levels of cleaved endocan

Alexandre Gaudet, Erika Parmentier, Nathalie De Freitas Caires, Lucie Portier, Sylvain Dubucquoi, Julien Poissy, Thibault Duburcq, Maxence Hureau, Philippe Lassalle, Daniel Mathieu

01.12.2019 | Letter | Ausgabe 1/2019 Open Access

Letter on “Synbiotics modulate gut microbiota and reduce enteritis and ventilator-associated pneumonia in patients with sepsis: a randomized controlled trial”

Alexander Reisinger, Vanessa Stadlbauer

01.12.2019 | Letter | Ausgabe 1/2019 Open Access

Soluble vascular endothelial cadherin: a promising marker of critical illness?

Ruyuan Zhang, Ranran Li, Yaoqing Tang

01.12.2019 | Letter | Ausgabe 1/2019 Open Access

Authors’ response to letter “Prediction of acute kidney injury in intensive care unit patients”

Hiroyuki Naruse, Hiroshi Takahashi, Junnichi Ishii

01.12.2019 | Letter | Ausgabe 1/2019 Open Access

Response to “Are fluids resuscitation the “Keyser Soze” of acute kidney injury in trauma patients?”

Anatole Harrois, Benjamin Soyer, Tobias Gauss, Sophie Hamada, Mathieu Raux, Jacques Duranteau, for the Traumabase® Group

01.12.2019 | Research | Ausgabe 1/2019 Open Access

Prognostic accuracy of the Hamilton Early Warning Score (HEWS) and the National Early Warning Score 2 (NEWS2) among hospitalized patients assessed by a rapid response team

Shannon M. Fernando, Alison E. Fox-Robichaud, Bram Rochwerg, Pierre Cardinal, Andrew J. E. Seely, Jeffrey J. Perry, Daniel I. McIsaac, Alexandre Tran, Steven Skitch, Benjamin Tam, Michael Hickey, Peter M. Reardon, Peter Tanuseputro, Kwadwo Kyeremanteng

01.12.2019 | Research | Ausgabe 1/2019 Open Access

Intravascular versus surface cooling for targeted temperature management after out-of-hospital cardiac arrest: an analysis of the TTH48 trial

Chiara De Fazio, Markus B. Skrifvars, Eldar Søreide, Jacques Creteur, Anders M. Grejs, Jesper Kjærgaard, Timo Laitio, Jens Nee, Hans Kirkegaard, Fabio Silvio Taccone

01.12.2019 | Review | Ausgabe 1/2019 Open Access

Diagnostic and therapeutic approach in adult patients with traumatic brain injury receiving oral anticoagulant therapy: an Austrian interdisciplinary consensus statement

Marion Wiegele, Herbert Schöchl, Alexander Haushofer, Martin Ortler, Johannes Leitgeb, Oskar Kwasny, Ronny Beer, Cihan Ay, Eva Schaden

01.12.2019 | Research | Ausgabe 1/2019 Open Access

Acute neuropathological consequences of short-term mechanical ventilation in wild-type and Alzheimer’s disease mice

Shouri Lahiri, Giovanna C. Regis, Yosef Koronyo, Dieu-Trang Fuchs, Julia Sheyn, Elizabeth H. Kim, Mitra Mastali, Jennifer E. Van Eyk, Padmesh S. Rajput, Patrick D. Lyden, Keith L. Black, E. Wesley Ely, Heather D. Jones, Maya Koronyo-Hamaoui

01.12.2019 | Research | Ausgabe 1/2019 Open Access

Emergency department triage prediction of clinical outcomes using machine learning models

Yoshihiko Raita, Tadahiro Goto, Mohammad Kamal Faridi, David F. M. Brown, Carlos A. Camargo Jr., Kohei Hasegawa

01.12.2019 | Research | Ausgabe 1/2019 Open Access

The prognostic value of optic nerve sheath diameter in patients with subarachnoid hemorrhage

Sangkil Lee, Yong Oh Kim, Ji Sun Baek, Jeong-Am Ryu

01.12.2019 | Commentary | Ausgabe 1/2019 Open Access

The chemical, biological, radiological and nuclear (CBRN) chain of survival: a new pragmatic and didactic tool used by Paris Fire Brigade

Franck Calamai, Clément Derkenne, Daniel Jost, Stéphane Travers, Isabelle Klein, Kilian Bertho, Frédéric Dorandeu, Michel Bignand, Bertrand Prunet

01.12.2019 | Research | Ausgabe 1/2019 Open Access

Association of extracerebral organ failure with 1-year survival and healthcare-associated costs after cardiac arrest: an observational database study

Pirkka T. Pekkarinen, Minna Bäcklund, Ilmar Efendijev, Rahul Raj, Daniel Folger, Erik Litonius, Ruut Laitio, Stepani Bendel, Sanna Hoppu, Tero Ala-Kokko, Matti Reinikainen, Markus B. Skrifvars

01.12.2019 | Research | Ausgabe 1/2019 Open Access

Early nasal high-flow versus Venturi mask oxygen therapy after lung resection: a randomized trial

Mariano Alberto Pennisi, Giuseppe Bello, Maria Teresa Congedo, Luca Montini, Dania Nachira, Gian Maria Ferretti, Elisa Meacci, Elisabetta Gualtieri, Gennaro De Pascale, Domenico Luca Grieco, Stefano Margaritora, Massimo Antonelli

01.12.2019 | Research | Ausgabe 1/2019 Open Access

Permissive versus restrictive temperature thresholds in critically ill children with fever and infection: a multicentre randomized clinical pilot trial

Mark J. Peters, Kerry Woolfall, Imran Khan, Elisabeth Deja, Paul R. Mouncey, Jerome Wulff, Alexina Mason, Rachel S. Agbeko, Elizabeth S. Draper, Blaise Fenn, Doug W. Gould, Abby Koelewyn, Nigel Klein, Christine Mackerness, Sian Martin, Lauran O’Neill, Samiran Ray, Padmanabhan Ramnarayan, Shane Tibby, Kentigern Thorburn, Lyvonne Tume, Jason Watkins, Paul Wellman, David A. Harrison, Kathryn M. Rowan, the FEVER Investigators on behalf of the Paediatric Intensive Care Society Study Group (PICS-SG)

01.12.2019 | Research | Ausgabe 1/2019 Open Access

Subjective right ventricle assessment by echo qualified intensive care specialists: assessing agreement with objective measures

Sam Orde, Michel Slama, Konstantin Yastrebov, Anthony Mclean, Stephen Huang, on behalf of the College of Intensive Care Medicine of Australia and New Zealand [CICM] Ultrasound Special Interest Group [USIG]

01.12.2019 | Letter | Ausgabe 1/2019 Open Access

Important methodological flaws in the recently published clinical prediction model the REMEMBER score

Anders Granholm, Anders Perner, Aksel Karl Georg Jensen, Morten Hylander Møller

01.12.2019 | Review | Ausgabe 1/2019 Open Access

Recruitment Maneuvers and Higher PEEP, the So-Called Open Lung Concept, in Patients with ARDS

Philip van der Zee, Diederik Gommers

01.12.2019 | Review | Ausgabe 1/2019 Open Access

ARDS in Obese Patients: Specificities and Management

Audrey De Jong, Daniel Verzilli, Samir Jaber

01.12.2019 | Review | Ausgabe 1/2019 Open Access

Physiological and Technical Considerations of Extracorporeal CO2 Removal

Christian Karagiannidis, Felix Hesselmann, Eddy Fan

01.12.2019 | Review | Ausgabe 1/2019 Open Access

Mechanical Circulatory Support Devices for Cardiogenic Shock: State of the Art

Ludhmila Abrahao Hajjar, Jean-Louis Teboul

01.12.2019 | Review | Ausgabe 1/2019 Open Access

Resuscitation Fluid Choices to Preserve the Endothelial Glycocalyx

Elissa M. Milford, Michael C. Reade

01.12.2019 | Review | Ausgabe 1/2019 Open Access

Uncovering Consciousness in Unresponsive ICU Patients: Technical, Medical and Ethical Considerations

Benjamin Rohaut, Andrey Eliseyev, Jan Claassen

01.12.2019 | Review | Ausgabe 1/2019 Open Access

Multidrug Resistant Gram-Negative Bacteria in Community-Acquired Pneumonia

Catia Cillóniz, Cristina Dominedò, Antoni Torres

01.12.2019 | Review | Ausgabe 1/2019 Open Access

Heterogeneity in sepsis: new biological evidence with clinical applications

Aleksandra Leligdowicz, Michael A. Matthay

01.12.2019 | Review | Ausgabe 1/2019 Open Access

Iron Metabolism: An Emerging Therapeutic Target in Critical Illness

Edward Litton, Jolene Lim

01.12.2019 | Review | Ausgabe 1/2019 Open Access

Sleep and Circadian Rhythm in Critical Illness

Irene Telias, Mary Elizabeth Wilcox

01.12.2019 | Research | Ausgabe 1/2019 Open Access

Organ system network analysis and biological stability in critically ill patients

Toshifumi Asada, Kent Doi, Ryota Inokuchi, Naoki Hayase, Miyuki Yamamoto, Naoto Morimura

01.12.2019 | Letter | Ausgabe 1/2019 Open Access

Validity of the relationship between mobility group box-1 protein and poor post–cardiac arrest neurological outcome during renal replacement therapy

Patrick M. Honore, David De Bels, Luc Kugener, Sebastien Redant, Rachid Attou, Andrea Gallerani, Herbert D. Spapen

01.12.2019 | Letter | Ausgabe 1/2019 Open Access

Incidence of hypotension according to the discontinuation order of vasopressors: a matter of pharmacokinetics

Ross Freebairn, Brigitte Hollander

01.12.2019 | Letter | Ausgabe 1/2019 Open Access

The complex kinetics of blood endocan during the time course of sepsis and acute respiratory distress syndrome

Alexandre Gaudet, Erika Parmentier, Sylvain Dubucquoi, Julien Poissy, Thibault Duburcq, Lucie Portier, Philippe Lassalle, Nathalie De Freitas Caires, Daniel Mathieu

01.12.2019 | Letter | Ausgabe 1/2019 Open Access

Response to “Weaning order of vasoactive drugs”

Kyeongman Jeon, Jae-Uk Song, Gee Young Suh

01.12.2019 | Letter | Ausgabe 1/2019 Open Access

The pharmacokinetic challenge of voriconazole therapy for cerebral aspergillosis in patients treated with ibrutinib

Rémy Nyga, Laura Simon, Taieb Chouaki, Caroline Delette, Youssef Bennis, Cedric Joseph, Jean-Pierre Marolleau, Michel Slama, Elie Zogheib, Julien Maizel

01.12.2019 | Research | Ausgabe 1/2019 Open Access

Transfusion requirements after head trauma: a randomized feasibility controlled trial

André L. N. Gobatto, Milena A. Link, Davi J. Solla, Estevão Bassi, Paulo F. Tierno, Wellingson Paiva, Fabio S. Taccone, Luiz M. Malbouisson

01.12.2019 | Letter | Ausgabe 1/2019 Open Access

Weaning order of vasoactive drugs

Vilto Michels Jr, Daisson José Trevisol

01.12.2019 | Research | Ausgabe 1/2019 Open Access

The effects and safety of vasopressin receptor agonists in patients with septic shock: a meta-analysis and trial sequential analysis

Libing Jiang, Yi Sheng, Xia Feng, Jing Wu

01.12.2019 | Letter | Ausgabe 1/2019 Open Access

State-level hospital compliance with and performance in the Centers for Medicaid & Medicare Services’ Early Management Severe Sepsis and Septic Shock Bundle

Jordan A. Kempker, Michael R. Kramer, Lance A. Waller, Henry E. Wang, Greg S. Martin

01.12.2019 | Research | Ausgabe 1/2019 Open Access

The association between autoimmune disease and 30-day mortality among sepsis ICU patients: a cohort study

Mallory Sheth, Corey M. Benedum, Leo Anthony Celi, Roger G. Mark, Natasha Markuzon

01.12.2019 | Letter | Ausgabe 1/2019 Open Access

Is cortical perfusion a reliable marker for predicting septic acute kidney injury?

Patrick M. Honore, David De Bels, Andrea Gallerani, Rachid Attou, Sebastien Redant, Leonel Barreto Gutierrez, Willem Boer

01.12.2019 | Research | Ausgabe 1/2019 Open Access

Development of a quality indicator set to measure and improve quality of ICU care for patients with traumatic brain injury

Jilske A. Huijben, Eveline J. A. Wiegers, Nicolette F. de Keizer, Andrew I. R. Maas, David Menon, Ari Ercole, Giuseppe Citerio, Fiona Lecky, Lindsay Wilson, Maryse C. Cnossen, Suzanne Polinder, Ewout W. Steyerberg, Mathieu van der Jagt, Hester F. Lingsma, the Delphi panel

01.12.2019 | Letter | Ausgabe 1/2019 Open Access

Some questions about preadmission metformin use and mortality in patients with sepsis and diabetes mellitus

Jiarong Ye, Qianrong Liang, Xiaotu Xi

01.12.2019 | Editorial | Ausgabe 1/2019 Open Access

Pediatric ARDS biomarkers: missing the random forest for the trees

Nadir Yehya

01.12.2019 | Research | Ausgabe 1/2019 Open Access

The European guideline on management of major bleeding and coagulopathy following trauma: fifth edition

Donat R. Spahn, Bertil Bouillon, Vladimir Cerny, Jacques Duranteau, Daniela Filipescu, Beverley J. Hunt, Radko Komadina, Marc Maegele, Giuseppe Nardi, Louis Riddez, Charles-Marc Samama, Jean-Louis Vincent, Rolf Rossaint

01.12.2019 | Research | Ausgabe 1/2019 Open Access

The effect of corticosteroids on mortality of patients with influenza pneumonia: a systematic review and meta-analysis

Yue-Nan Ni, Guo Chen, Jiankui Sun, Bin-Miao Liang, Zong-An Liang

01.12.2019 | Research | Ausgabe 1/2019 Open Access

A meta-analysis of the resuscitative effects of mechanical and manual chest compression in out-of-hospital cardiac arrest patients

Ni Zhu, Qi Chen, Zhixia Jiang, Futuan Liao, Bujin Kou, Hui Tang, Manhong Zhou

01.12.2019 | Research | Ausgabe 1/2019 Open Access

Time to epinephrine treatment is associated with the risk of mortality in children who achieve sustained ROSC after traumatic out-of-hospital cardiac arrest

Yan-Ren Lin, Meng-Huan Wu, Tren-Yi Chen, Yuan-Jhen Syue, Mei-Chueh Yang, Tsung-Han Lee, Chih-Ming Lin, Chu-Chung Chou, Chin-Fu Chang, Chao-Jui Li

01.12.2019 | Research | Ausgabe 1/2019 Open Access

PO2 oscillations induce lung injury and inflammation

Stefan Boehme, Erik K. Hartmann, Thomas Tripp, Serge C. Thal, Matthias David, Dietmar Abraham, James E. Baumgardner, Klaus Markstaller, Klaus U. Klein

01.12.2019 | Review | Ausgabe 1/2019 Open Access

Dysphagia in the intensive care unit: epidemiology, mechanisms, and clinical management

Patrick Zuercher, Céline S. Moret, Rainer Dziewas, Joerg C. Schefold

01.12.2019 | Review | Ausgabe 1/2019 Open Access

Optimization of the treatment with beta-lactam antibiotics in critically ill patients—guidelines from the French Society of Pharmacology and Therapeutics (Société Française de Pharmacologie et Thérapeutique—SFPT) and the French Society of Anaesthesia and Intensive Care Medicine (Société Française d’Anesthésie et Réanimation—SFAR)

Romain Guilhaumou, Sihem Benaboud, Youssef Bennis, Claire Dahyot-Fizelier, Eric Dailly, Peggy Gandia, Sylvain Goutelle, Sandrine Lefeuvre, Nicolas Mongardon, Claire Roger, Julien Scala-Bertola, Florian Lemaitre, Marc Garnier

01.12.2019 | Research | Ausgabe 1/2019 Open Access

Safety and efficacy of volume-based feeding in critically ill, mechanically ventilated adults using the ‘Protein & Energy Requirements Fed for Every Critically ill patient every Time’ (PERFECT) protocol: a before-and-after study

Sue Brierley-Hobson, Graham Clarke, Vincent O’Keeffe

01.12.2019 | Research | Ausgabe 1/2019 Open Access

Flagellin attenuates experimental sepsis in a macrophage-dependent manner

Xiaoliang Yang, Yibing Yin, Xingxing Yan, Zebo Yu, Yi Liu, Ju Cao

01.12.2019 | Research | Ausgabe 1/2019 Open Access

Death after awakening from post-anoxic coma: the “Best CPC” project

Fabio Silvio Taccone, Janneke Horn, Christian Storm, Alain Cariou, Claudio Sandroni, Hans Friberg, Cornelia Astrid Hoedemaekers, Mauro Oddo

01.12.2019 | Research | Ausgabe 1/2019 Open Access

Cytokine clearance with CytoSorb® during cardiac surgery: a pilot randomized controlled trial

Elettra C Poli, Lorenzo Alberio, Anna Bauer-Doerries, Carlo Marcucci, Aurélien Roumy, Matthias Kirsch, Eleonora De Stefano, Lucas Liaudet, Antoine G Schneider

01.12.2019 | Editorial | Ausgabe 1/2019 Open Access

Is intravenous vitamin C contraindicated in patients with G6PD deficiency?

Paul E. Marik

01.12.2019 | Research | Ausgabe 1/2019 Open Access

Sequential organ failure assessment score is an excellent operationalization of disease severity of adult patients with hospitalized community acquired pneumonia – results from the prospective observational PROGRESS study

Peter Ahnert, Petra Creutz, Katrin Horn, Fabian Schwarzenberger, Michael Kiehntopf, Hamid Hossain, Michael Bauer, Frank Martin Brunkhorst, Konrad Reinhart, Uwe Völker, Trinad Chakraborty, Martin Witzenrath, Markus Löffler, Norbert Suttorp, Markus Scholz, The PROGRESS Study Group

01.12.2019 | Research | Ausgabe 1/2019 Open Access

Impact of nutrition route on microaspiration in critically ill patients with shock: a planned ancillary study of the NUTRIREA-2 trial

Saad Nseir, Amélie Le Gouge, Jean-Baptiste Lascarrou, Jean-Claude Lacherade, Emmanuelle Jaillette, Jean-Paul Mira, Emmanuelle Mercier, Pierre-Louis Declercq, Michel Sirodot, Gaël Piton, François Tinturier, Elisabeth Coupez, Stéphane Gaudry, Michel Djibré, Didier Thevenin, Jeremy Pasco, Malika Balduyck, Farid Zerimech, Jean Reignier

01.12.2019 | Research | Ausgabe 1/2019 Open Access

Machine learning for the prediction of volume responsiveness in patients with oliguric acute kidney injury in critical care

Zhongheng Zhang, Kwok M. Ho, Yucai Hong

01.12.2019 | Research | Ausgabe 1/2019 Open Access

Neutrophil extracellular traps (NETs) exacerbate severity of infant sepsis

David F. Colón, Carlos W. Wanderley, Marcelo Franchin, Camila M. Silva, Carlos H. Hiroki, Fernanda V. S. Castanheira, Paula B. Donate, Alexandre H. Lopes, Leila C. Volpon, Silvia K. Kavaguti, Vanessa F. Borges, Cesar A. Speck-Hernandez, Fernando Ramalho, Ana P. Carlotti, Fabio Carmona, Jose C. Alves-Filho, Foo Y. Liew, Fernando Q. Cunha

01.12.2019 | Letter | Ausgabe 1/2019 Open Access

Lack of relationship between fasting plasma citrulline and glucose absorption: do not underestimate the role of the failing kidney!

Patrick M. Honore, David De Bels, Andrea Gallerani, Rachid Attou, Willem Boer

01.12.2019 | Research | Ausgabe 1/2019 Open Access

What is the lowest change in cardiac output that transthoracic echocardiography can detect?

Mathieu Jozwiak, Pablo Mercado, Jean-Louis Teboul, Anouar Benmalek, Julia Gimenez, François Dépret, Christian Richard, Xavier Monnet

01.12.2019 | Research | Ausgabe 1/2019 Open Access

Microcirculatory perfusion disturbances following cardiac surgery with cardiopulmonary bypass are associated with in vitro endothelial hyperpermeability and increased angiopoietin-2 levels

Nicole A. M. Dekker, Anoek L. I. van Leeuwen, Willem W. J. van Strien, Jisca Majolée, Robert Szulcek, Alexander B. A. Vonk, Peter L. Hordijk, Christa Boer, Charissa E. van den Brom

01.12.2019 | Research | Ausgabe 1/2019 Open Access

Cardiovascular determinants of resuscitation from sepsis and septic shock

Fabio Guarracino, Pietro Bertini, Michael R. Pinsky

01.12.2019 | Research | Ausgabe 1/2019 Open Access

Heterogeneity of regional inflection points from pressure-volume curves assessed by electrical impedance tomography

Gaetano Scaramuzzo, Savino Spadaro, Andreas D. Waldmann, Stephan H. Böhm, Riccardo Ragazzi, Elisabetta Marangoni, Valentina Alvisi, Elena Spinelli, Tommaso Mauri, Carlo Alberto Volta

01.12.2019 | Letter | Ausgabe 1/2019 Open Access

Neurally adjusted ventilatory assist decreases work of breathing during non-invasive ventilation in infants with severe bronchiolitis

Florent Baudin, Guillaume Emeriaud, Sandrine Essouri, Jennifer Beck, Etienne Javouhey, Claude Guerin

01.12.2019 | Letter | Ausgabe 1/2019 Open Access

Comment on the article: “Microvascular effects of intravenous esmolol in patients with normal cardiac function undergoing postoperative atrial fibrillation: a prospective pilot study in cardiothoracic surgery”

Ye Ying Zheng, Fei Guo, Bin Lu, Qiang Li

01.12.2019 | Research | Ausgabe 1/2019 Open Access

Mechanical ventilation causes diaphragm dysfunction in newborn lambs

Feng Liang, Guillaume Emeriaud, Dilson E. Rassier, Dong Shang, Ekaterina Gusev, Sabah N. A. Hussain, Michael Sage, Benjamin Crulli, Etienne Fortin-Pellerin, Jean-Paul Praud, Basil J. Petrof

01.12.2019 | Commentary | Ausgabe 1/2019 Open Access

Broad spectrum vasopressors: a new approach to the initial management of septic shock?

Lakhmir S. Chawla, Marlies Ostermann, Lui Forni, George F. Tidmarsh

01.12.2019 | Research | Ausgabe 1/2019 Open Access

A prospective investigation of interleukin-8 levels in pediatric acute respiratory failure and acute respiratory distress syndrome

Heidi Flori, Anil Sapru, Michael W. Quasney, Ginny Gildengorin, Martha A. Q. Curley, Michael A. Matthay, Mary K. Dahmer, for the BALI and RESTORE Study Investigators, Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network

01.12.2019 | Letter | Ausgabe 1/2019 Open Access

Application of MR-ProADM to predict prevention of hospitalisation, derived from a multi-centre study

Milo Cullinan, Sara Graziadio, David Ashley Price

01.12.2019 | Research | Ausgabe 1/2019 Open Access

Sedation practices and clinical outcomes in mechanically ventilated patients in a prospective multicenter cohort

Romina E. Aragón, Alvaro Proaño, Nicole Mongilardi, Aldo de Ferrari, Phabiola Herrera, Rollin Roldan, Enrique Paz, Amador A. Jaymez, Eduardo Chirinos, Jose Portugal, Rocio Quispe, Roy G. Brower, William Checkley

01.12.2019 | Research | Ausgabe 1/2019 Open Access

TCR activation mimics CD127lowPD-1high phenotype and functional alterations of T lymphocytes from septic shock patients

Julie Mouillaux, Camille Allam, Morgane Gossez, Thomas Uberti, Benjamin Delwarde, Jack Hayman, Thomas Rimmelé, Julien Textoris, Guillaume Monneret, Estelle Peronnet, Fabienne Venet

01.12.2019 | Commentary | Ausgabe 1/2019 Open Access

Liberal versus conservative oxygen therapy in critically ill patients: using the fragility index to determine robust results

Maria Vargas, Giuseppe Servillo

01.12.2019 | Letter | Ausgabe 1/2019 Open Access

vvECMO can be avoided by a transpulmonary pressure guided open lung concept in patients with severe ARDS

Philip van der Zee, Dinis Dos Reis Miranda, Han Meeder, Henrik Endeman, Diederik Gommers

01.12.2019 | Research | Ausgabe 1/2019 Open Access

Control of respiratory drive by extracorporeal CO2 removal in acute exacerbation of COPD breathing on non-invasive NAVA

Christian Karagiannidis, Stephan Strassmann, Sarah Schwarz, Michaela Merten, Eddy Fan, Jennifer Beck, Christer Sinderby, Wolfram Windisch

01.12.2019 | Editorial | Ausgabe 1/2019 Open Access

Intelligently learning from data

Edward Palmer, Roman Klapaukh, Steve Harris, Mervyn Singer, the INFORM-lab

01.12.2019 | Letter | Ausgabe 1/2019 Open Access

Response to “Incidence of hypotension according to the discontinuation order of vasopressors: a matter of pharmacokinetics”

Kyeongman Jeon, Jae-Uk Song, Gee Young Suh

01.12.2019 | Letter | Ausgabe 1/2019 Open Access

Trial sequential analysis suggested the potential overestimated effect of carbonic anhydrase inhibitor for respiratory failure and metabolic alkalosis

Meng-Si Luo, Hui-Zi Li, Guan-Jiang Huang, Lun Wu

01.12.2019 | Editorial | Ausgabe 1/2019 Open Access

Composed endotypes to guide antibiotic discontinuation in sepsis

Jesus F. Bermejo-Martin, David Andaluz-Ojeda, Marta Martin-Fernandez, Cesar Aldecoa, Raquel Almansa

01.12.2019 | Letter | Ausgabe 1/2019 Open Access

Biomarkers to guide antibiotic timing and administration in infected patients presenting to the emergency department

Mari Rosenqvist, Darius Cameron Wilson, Lena Tegnér, Maria Bengtsson-Toni, Marjaneh Peyman, Juan Gonzalez del Castillo, Kordo Saeed, Olle Melander

01.12.2019 | Correction | Ausgabe 1/2019 Open Access

Correction to: Early versus late initiation of renal replacement therapy impacts mortality in patients with acute kidney injury post cardiac surgery: a meta-analysis

Honghong Zou, Qianwen Hong, Gaosi XU

01.12.2019 | Research | Ausgabe 1/2019 Open Access

Epidemiology of infective endocarditis in French intensive care units over the 1997–2014 period—from CUB-Réa Network

Jérémie Joffre, Guillaume Dumas, Philippe Aegerter, Vincent Dubée, Naike Bigé, Gabriel Preda, Jean-Luc Baudel, Eric Maury, Bertrand Guidet, Hafid Ait-Oufella, on behalf of the CUB-Réa Network

01.12.2019 | Letter | Ausgabe 1/2019 Open Access

Angiotensin II in ECMO patients: a word of caution

Elio Antonucci, Fabio Silvio Taccone

01.12.2019 | Letter | Ausgabe 1/2019 Open Access

Optimizing ceftolozane-tazobactam dosage in critically ill patients during continuous venovenous hemodiafiltration

Gerardo Aguilar, Rafael Ferriols, Sara Martínez-Castro, Carlos Ezquer, Ernesto Pastor, José A. Carbonell, Manuel Alós, David Navarro

01.12.2019 | Letter | Ausgabe 1/2019 Open Access

Quality and quantity of sample size is crucial in clinical studies to exclude association: antimicrobial exposure and the risk of delirium in critically ill patients

Rashid Nadeem, Zainab Ameer Obeida, Sahish Kamat, Ahmed Nazir Elsousi

01.12.2019 | Letter | Ausgabe 1/2019 Open Access

Renin-angiotensin-aldosterone system blockers after KDIGO stage 3 acute kidney injury: use and impact on 2-year mortality in the AKIKI trial

Mathilde Scarton, Anne Oppenheimer, Khalil Chaïbi, Didier Dreyfuss, Stéphane Gaudry

01.12.2019 | Editorial | Ausgabe 1/2019 Open Access

The global challenge of Candida auris in the intensive care unit

Andrea Cortegiani, Giovanni Misseri, Antonino Giarratano, Matteo Bassetti, David Eyre

01.12.2019 | Letter | Ausgabe 1/2019 Open Access

Procalcitonin is an essential biomarker for hydrocortisone, ascorbic acid, and thiamine (HAT) therapy in patients with sepsis

Paul E. Marik

01.12.2019 | Research | Ausgabe 1/2019 Open Access

Influenza and associated co-infections in critically ill immunosuppressed patients

Ignacio Martin-Loeches, Virginie Lemiale, Pierce Geoghegan, Mary Aisling McMahon, Peter Pickkers, Marcio Soares, Anders Perner, Tine Sylvest Meyhoff, Ramin Brandt Bukan, Jordi Rello, Philippe R. Bauer, Andry van de Louw, Fabio Silvio Taccone, Jorge Salluh, Pleun Hemelaar, Peter Schellongowski, Katerina Rusinova, Nicolas Terzi, Sangeeta Mehta, Massimo Antonelli, Achille Kouatchet, Pål Klepstad, Miia Valkonen, Precious Pearl Landburg, Andreas Barratt-Due, Fabrice Bruneel, Frédéric Pène, Victoria Metaxa, Anne Sophie Moreau, Virginie Souppart, Gaston Burghi, Christophe Girault, Ulysses V. A. Silva, Luca Montini, Francois Barbier, Lene B. Nielsen, Benjamin Gaborit, Djamel Mokart, Sylvie Chevret, Elie Azoulay, For the Efraim investigators and the Nine-I study group

01.12.2019 | Letter | Ausgabe 1/2019 Open Access

Social and economic problems of ICU survivors identified by a structured social welfare consultation

J. M. McPeake, P. Henderson, G. Darroch, T. J. Iwashyna, P. MacTavish, C. Robinson, T. Quasim

01.12.2019 | Letter | Ausgabe 1/2019 Open Access

When circulatory death does not come in time in potential organ donors

Angela Kotsopoulos, Nichon Jansen, Wilson Farid Abdo

01.12.2019 | Research | Ausgabe 1/2019 Open Access

Quantitative pupillometry for the monitoring of intracranial hypertension in patients with severe traumatic brain injury

Fritz-Patrick Jahns, John Paul Miroz, Mahmoud Messerer, Roy T. Daniel, Fabio Silvio Taccone, Philippe Eckert, Mauro Oddo

01.12.2019 | Research | Ausgabe 1/2019 Open Access

Heterogeneity of treatment effect by baseline risk of mortality in critically ill patients: re-analysis of three recent sepsis and ARDS randomised controlled trials

Shalini Santhakumaran, Anthony Gordon, A. Toby Prevost, Cecilia O’Kane, Daniel F. McAuley, Manu Shankar-Hari

01.12.2019 | Letter | Ausgabe 1/2019 Open Access

Does training level affect the accuracy of visual assessment of capillary refill time?

Koichiro Shinozaki, Lee S. Jacobson, Kota Saeki, Naoki Kobayashi, Steve Weisner, Julianne M. Falotico, Timmy Li, Junhwan Kim, Joshua W. Lampe, Lance B. Becker

01.12.2019 | Research | Ausgabe 1/2019 Open Access

Retrospective cohort study of hospital variation in airway management during in-hospital cardiac arrest and the association with patient survival: insights from Get With The Guidelines-Resuscitation

Steven M. Bradley, Yunshu Zhou, Satya Krishna Ramachandran, Milo Engoren, Michael Donnino, Saket Girotra

01.12.2019 | Research | Ausgabe 1/2019 Open Access

Fluid management in patients undergoing cardiac surgery: effects of an acetate- versus lactate-buffered balanced infusion solution on hemodynamic stability (HEMACETAT)

Carmen A. Pfortmueller, Livia Faeh, Martin Müller, Balthasar Eberle, Hansjörg Jenni, Björn Zante, Josef Prazak, Lars Englberger, Jukka Takala, Stephan M. Jakob

01.12.2019 | Editorial | Ausgabe 1/2019 Open Access

How I monitor cerebral autoregulation

Samuel P. Klein, Bart Depreitere, Geert Meyfroidt

01.12.2019 | Research | Ausgabe 1/2019 Open Access

The effect of adhesive tape versus endotracheal tube fastener in critically ill adults: the endotracheal tube securement (ETTS) randomized controlled trial

Janna S. Landsperger, Jesse M. Byram, Bradley D. Lloyd, Todd W. Rice, for the Pragmatic Critical Care Research Group

01.12.2019 | Research | Ausgabe 1/2019 Open Access

Pyroglutamic acidosis by glutathione regeneration blockage in critical patients with septic shock

Yenifer Gamarra, Felipe C. Santiago, Jorge Molina-López, José Castaño, Lourdes Herrera-Quintana, Álvaro Domínguez, Elena Planells

01.12.2019 | Research | Ausgabe 1/2019 Open Access

Renal function after out-of-hospital cardiac arrest; the influence of temperature management and coronary angiography, a post hoc study of the target temperature management trial

Malin Rundgren, Susann Ullén, Matt P. G. Morgan, Guy Glover, Julius Cranshaw, Nawaf Al-Subaie, Andrew Walden, Michael Joannidis, Marlies Ostermann, Josef Dankiewicz, Niklas Nielsen, Matthew P. Wise

01.12.2019 | Letter | Ausgabe 1/2019 Open Access

Hypothermia after decompressive hemicraniectomy in treatment of malignant middle cerebral artery stroke: comment on the randomized clinical trial

N. Engrand, M. Mazighi, V. Dinkelacker

01.12.2019 | Research | Ausgabe 1/2019 Open Access

Adding an orange to the banana bag: vitamin C deficiency is common in alcohol use disorders

Paul E. Marik, Amanda Liggett

01.12.2019 | Letter | Ausgabe 1/2019 Open Access

Inducible metabolic pathway for citrate metabolism in case of major liver dysfunction: fact or fiction?

Patrick M. Honore, David De Bels, Sebastien Redant, Rachid Attou, Luc Kugener, Willem Boer

01.12.2019 | Letter | Ausgabe 1/2019 Open Access

Letter in response to “Vascular endothelial cadherin shedding is more severe in sepsis patients with severe acute kidney injury”

Richard W Pierce

01.12.2019 | Research | Ausgabe 1/2019 Open Access

Comparative efficacy of vasoactive medications in patients with septic shock: a network meta-analysis of randomized controlled trials

Lu Cheng, Jing Yan, Shutang Han, Qiuhua Chen, Mingqi Chen, Hua Jiang, Jun Lu

01.12.2019 | Research | Ausgabe 1/2019 Open Access

Nuclear magnetic resonance-based serum metabolomic analysis reveals different disease evolution profiles between septic shock survivors and non-survivors

Zhicheng Liu, Mohamed N. Triba, Roland Amathieu, Xiangping Lin, Nadia Bouchemal, Edith Hantz, Laurence Le Moyec, Philippe Savarin

01.12.2019 | Research | Ausgabe 1/2019 Open Access

Is systematic fecal carriage screening of extended-spectrum beta-lactamase-producing Enterobacteriaceae still useful in intensive care unit: a systematic review

Renaud Prevel, Alexandre Boyer, Fatima M’Zali, Agnès Lasheras, Jean-Ralph Zahar, Anne-Marie Rogues, Didier Gruson

01.12.2019 | Research | Ausgabe 1/2019 Open Access

Near-infrared spectroscopy after out-of-hospital cardiac arrest

Pekka Jakkula, Johanna Hästbacka, Matti Reinikainen, Ville Pettilä, Pekka Loisa, Marjaana Tiainen, Erika Wilkman, Stepani Bendel, Thomas Birkelund, Anni Pulkkinen, Minna Bäcklund, Sirkku Heino, Sari Karlsson, Hiski Kopponen, Markus B. Skrifvars

01.12.2019 | Research | Ausgabe 1/2019 Open Access

Temporal change in characteristics and outcomes of acute kidney injury on renal replacement therapy in intensive care units: analysis of a nationwide administrative database in Japan, 2007–2016

Yoshihisa Miyamoto, Masao Iwagami, Shotaro Aso, Hideo Yasunaga, Hiroki Matsui, Kiyohide Fushimi, Yoshifumi Hamasaki, Masaomi Nangaku, Kent Doi

01.12.2019 | Letter | Ausgabe 1/2019 Open Access

The challenge of removal of sepsis markers by continuous hemofiltration

Patrick M. Honore, David De Bels, Rachid Attou, Sebastien Redant, Kianoush Kashani

01.12.2019 | Letter | Ausgabe 1/2019 Open Access

Should ECMO be used in cardiogenic shock?

Orhan Gokalp, Koksal Donmez, Hasan Iner, Gamze Gokalp, Yuksel Besir, Nihan Karakas Yesilkaya, Levent Yilik, Ali Gurbuz

01.12.2019 | Research | Ausgabe 1/2019 Open Access

Patterns of utilization and effects of hospital-specific factors on physical, occupational, and speech therapy for critically ill patients with acute respiratory failure in the USA: results of a 5-year sample

Clare C. Prohaska, Peter D. Sottile, Amy Nordon-Craft, Matt D. Gallagher, Ellen L. Burnham, Brendan J. Clark, Michael Ho, Tyree H. Kiser, R. William Vandivier, Wenhui Liu, Margaret Schenkman, Marc Moss

01.12.2019 | Editorial | Ausgabe 1/2019 Open Access

How I ventilate an obese patient

Lorenzo Ball, Paolo Pelosi

01.12.2019 | Editorial | Ausgabe 1/2019 Open Access

How I manage a difficult intubation

Jonathan D. Casey, Matthew W. Semler, Kevin High, Wesley H. Self

01.12.2019 | Letter | Ausgabe 1/2019 Open Access

Are we really preventing lung collapse with APRV?

Ryota Sato, Natsumi Hamahata, Ehab G. Daoud

01.12.2019 | Research | Ausgabe 1/2019 Open Access

Time course of fluid responsiveness in sepsis: the fluid challenge revisiting (FCREV) study

Claire Roger, Laurent Zieleskiewicz, Christophe Demattei, Karim Lakhal, Gael Piton, Benjamin Louart, Jean-Michel Constantin, Russell Chabanne, Jean-Sébastien Faure, Yazine Mahjoub, Isabelle Desmeulles, Hervé Quintard, Jean-Yves Lefrant, Laurent Muller, AzuRea Group

01.12.2019 | Research | Ausgabe 1/2019 Open Access

High-flow nasal cannula oxygen therapy versus conventional oxygen therapy in patients after planned extubation: a systematic review and meta-analysis

Youfeng Zhu, Haiyan Yin, Rui Zhang, Xiaoling Ye, Jianrui Wei

01.12.2019 | Letter | Ausgabe 1/2019 Open Access

Response

Huoyan Liang, Xianfei Ding, Tongwen Sun

01.12.2019 | Research | Ausgabe 1/2019 Open Access

An overview of positive cultures and clinical outcomes in septic patients: a sub-analysis of the Prehospital Antibiotics Against Sepsis (PHANTASi) trial

Rishi S. Nannan Panday, Eline M. J. Lammers, Nadia Alam, Prabath W. B. Nanayakkara

01.12.2019 | Letter | Ausgabe 1/2019 Open Access

How to treat combined respiratory and metabolic acidosis after extracorporeal cardiopulmonary resuscitation?

Xavier Bemtgen, Florentine Schroth, Tobias Wengenmayer, Paul M. Biever, Daniel Duerschmied, Christoph Benk, Christoph Bode, Dawid L. Staudacher

01.12.2019 | Letter | Ausgabe 1/2019 Open Access

Endocan removal during continuous renal replacement therapy: does it affect the reliability of this biomarker?

Patrick M. Honore, David De Bels, Rachid Attou, Sebastien Redant, Andrea Gallerani, Kianoush Kashani

01.12.2019 | Research | Ausgabe 1/2019 Open Access

Clinically relevant pharmacokinetic knowledge on antibiotic dosing among intensive care professionals is insufficient: a cross-sectional study

Lucas M. Fleuren, Luca F. Roggeveen, Tingjie Guo, Petr Waldauf, Peter H. J. van der Voort, Rob J. Bosman, Eleonora L. Swart, Armand R. J. Girbes, Paul W. G. Elbers

01.12.2019 | Research | Ausgabe 1/2019 Open Access

Describing organ dysfunction in the intensive care unit: a cohort study of 20,000 patients

Andrea Soo, Danny J. Zuege, Gordon H. Fick, Daniel J. Niven, Luc R. Berthiaume, Henry T. Stelfox, Christopher J. Doig

01.12.2019 | Research | Ausgabe 1/2019 Open Access

Identifying patients’ support needs following critical illness: a scoping review of the qualitative literature

J. King, B. O’Neill, P. Ramsay, M. A. Linden, A. Darweish Medniuk, J. Outtrim, B. Blackwood

01.12.2019 | Letter | Ausgabe 1/2019 Open Access

Letter on “Sigh maneuver to enhance assessment of fluid responsiveness during pressure support ventilation”

Khaoula Meddeb, Mohamed Boussarsar

01.12.2019 | Letter | Ausgabe 1/2019 Open Access

Red blood cell transfusion may be more detrimental than anemia for the clinical outcome of patients with severe traumatic brain injury

Santiago R. Leal-Noval, María D. Rincón-Ferrari, Manuel Múñoz-Gómez

01.12.2019 | Research | Ausgabe 1/2019 Open Access

Procalcitonin levels in candidemia versus bacteremia: a systematic review

Andrea Cortegiani, Giovanni Misseri, Mariachiara Ippolito, Matteo Bassetti, Antonino Giarratano, Ignacio Martin-Loeches, Sharon Einav

01.12.2019 | Research | Ausgabe 1/2019 Open Access

Albumin infusion rate and plasma volume expansion: a randomized clinical trial in postoperative patients after major surgery

Svajunas Statkevicius, Johan Bonnevier, Jane Fisher, Björn P. Bark, Erik Larsson, Carl M. Öberg, Päivi Kannisto, Bobby Tingstedt, Peter Bentzer

01.12.2019 | Research | Ausgabe 1/2019 Open Access

Continuous monitoring of intrinsic PEEP based on expired CO2 kinetics: an experimental validation study

Sarah Heili-Frades, Fernando Suarez-Sipmann, Arnoldo Santos, Maria Pilar Carballosa, Alba Naya-Prieto, Carlos Castilla-Reparaz, Maria Jesús Rodriguez-Nieto, Nicolás González-Mangado, German Peces -Barba

01.12.2019 | Editorial | Ausgabe 1/2019 Open Access

Acute kidney injury after cardiac arrest: the role of coronary angiography and temperature management

Angélique M. E. Spoelstra-de Man, Heleen M. Oudemans-van Straaten

01.12.2019 | Viewpoint | Ausgabe 1/2019 Open Access

Automated continuous noninvasive ward monitoring: future directions and challenges

Ashish K. Khanna, Phillip Hoppe, Bernd Saugel

01.12.2019 | Research | Ausgabe 1/2019 Open Access

Dysbiosis of the intestinal microbiota in neurocritically ill patients and the risk for death

Ruoting Xu, Chuhong Tan, Jiajia Zhu, Xiuli Zeng, Xuxuan Gao, Qiheng Wu, Qiong Chen, Huidi Wang, Hongwei Zhou, Yan He, Suyue Pan, Jia Yin

01.12.2019 | Research | Ausgabe 1/2019 Open Access

Frequency and mortality of septic shock in Europe and North America: a systematic review and meta-analysis

Jean-Louis Vincent, Gabriel Jones, Sholto David, Elena Olariu, Kevin K. Cadwell

01.12.2019 | Research | Ausgabe 1/2019 Open Access

Post-stroke treatment with argon attenuated brain injury, reduced brain inflammation and enhanced M2 microglia/macrophage polarization: a randomized controlled animal study

Jingjin Liu, Kay Nolte, Gary Brook, Lisa Liebenstund, Agnieszka Weinandy, Anke Höllig, Michael Veldeman, Antje Willuweit, Karl-Josef Langen, Rolf Rossaint, Mark Coburn

01.12.2019 | Letter | Ausgabe 1/2019 Open Access

Short-term assist devices in postcardiotomy cardiogenic shock

Hasan Iner, Nihan Karakas Yesilkaya, Yuksel Besir, Gamze Gokalp, Orhan Gokalp, Levent Yilik, Ali Gurbuz

01.12.2019 | Research | Ausgabe 1/2019 Open Access

Trying to identify who may benefit most from future vitamin D intervention trials: a post hoc analysis from the VITDAL-ICU study excluding the early deaths

Gennaro Martucci, Dayre McNally, Dhruv Parekh, Paul Zajic, Fabio Tuzzolino, Antonio Arcadipane, Kenneth B. Christopher, Harald Dobnig, Karin Amrein

01.12.2019 | Letter | Ausgabe 1/2019 Open Access

Effect of high-flow nasal therapy on dyspnea, comfort, and respiratory rate

Andrea Cortegiani, Claudia Crimi, Alberto Noto, Yigal Helviz, Antonino Giarratano, Cesare Gregoretti, Sharon Einav

01.12.2019 | Research | Ausgabe 1/2019 Open Access

In-hospital mortality associated with the misdiagnosis or unidentified site of infection at admission

Toshikazu Abe, Yasuharu Tokuda, Atsushi Shiraishi, Seitaro Fujishima, Toshihiko Mayumi, Takehiro Sugiyama, Gautam A. Deshpande, Yasukazu Shiino, Toru Hifumi, Yasuhiro Otomo, Kohji Okamoto, Joji Kotani, Yuichiro Sakamoto, Junichi Sasaki, Shin-ichiro Shiraishi, Kiyotsugu Takuma, Akiyoshi Hagiwara, Kazuma Yamakawa, Naoshi Takeyama, Satoshi Gando, for the JAAM SPICE Study Group

01.12.2019 | Editorial | Ausgabe 1/2019 Open Access

ELS (Ethical Life Support): a new teaching tool for medical ethics

Marco Vergano, Giuseppe Naretto, Fabrizio Elia, Enrico Gandolfo, Chiara Nebris Calliera, Giuseppe R. Gristina

01.12.2019 | Research | Ausgabe 1/2019 Open Access

Population pharmacokinetics of total and unbound concentrations of intravenous posaconazole in adult critically ill patients

Fekade B. Sime, Catherine J. Byrne, Suzanne Parker, Janine Stuart, Jenie Butler, Therese Starr, Saurabh Pandey, Steven C. Wallis, Jeffrey Lipman, Jason A. Roberts

01.12.2019 | Review | Ausgabe 1/2019 Open Access

Reversal of oral anticoagulation in patients with acute intracerebral hemorrhage

Joji B. Kuramatsu, Jochen A. Sembill, Hagen B. Huttner

01.12.2019 | Research | Ausgabe 1/2019 Open Access

Examining the weekend effect across ICU performance metrics

Louis Faust, Keith Feldman, Nitesh V. Chawla

01.12.2019 | Research | Ausgabe 1/2019 Open Access

The ecological effects of selective decontamination of the digestive tract (SDD) on antimicrobial resistance: a 21-year longitudinal single-centre study

Sophie Buitinck, Rogier Jansen, Saskia Rijkenberg, Jos P. J. Wester, Rob J. Bosman, Nardo J. M. van der Meer, Peter H. J. van der Voort

01.12.2019 | Review | Ausgabe 1/2019 Open Access

Decompressive craniectomy for acute ischemic stroke

Thomas Beez, Christopher Munoz-Bendix, Hans-Jakob Steiger, Kerim Beseoglu

01.12.2019 | Editorial | Ausgabe 1/2019 Open Access

Interventions to improve cardiopulmonary resuscitation: a review of meta-analyses and future agenda

Athanasios Chalkias, John P. A. Ioannidis

01.12.2019 | Research | Ausgabe 1/2019 Open Access

Mottling score is a strong predictor of 14-day mortality in septic patients whatever vasopressor doses and other tissue perfusion parameters

Guillaume Dumas, Jean-Rémi Lavillegrand, Jérémie Joffre, Naïke Bigé, Edmilson Bastos de-Moura, Jean-Luc Baudel, Sylvie Chevret, Bertrand Guidet, Eric Maury, Fabio Amorim, Hafid Ait-Oufella

01.12.2019 | Research | Ausgabe 1/2019 Open Access

Aetiology and outcomes of sepsis in adults in sub-Saharan Africa: a systematic review and meta-analysis

Joseph M. Lewis, Nicholas A. Feasey, Jamie Rylance

01.12.2019 | Research | Ausgabe 1/2019 Open Access

Prevalence of post-traumatic stress disorder symptoms in adult critical care survivors: a systematic review and meta-analysis

Cássia Righy, Regis Goulart Rosa, Rodrigo Teixeira Amancio da Silva, Renata Kochhann, Celina Borges Migliavaca, Caroline Cabral Robinson, Stefania Pigatto Teche, Cassiano Teixeira, Fernando Augusto Bozza, Maicon Falavigna

01.12.2019 | Review | Ausgabe 1/2019 Open Access

Influenza virus-related critical illness: prevention, diagnosis, treatment

Eric J. Chow, Joshua D. Doyle, Timothy M. Uyeki

01.12.2019 | Letter | Ausgabe 1/2019 Open Access

Influence of pathogen and focus of infection on procalcitonin values in sepsis: are there additional confounding factors?

Patrick M. Honore, David De Bels, Rachid Attou, Sebastien Redant, Andrea Gallerani, Kianoush Kashani

01.12.2019 | Editorial | Ausgabe 1/2019 Open Access

How to achieve nutrition goals by actual nutrition guidelines

Christian Stoppe, Jean-Charles Preiser, Daren Heyland

01.12.2019 | Research | Ausgabe 1/2019 Open Access

Detailed measurements of oesophageal pressure during mechanical ventilation with an advanced high-resolution manometry catheter

Per Persson, Rebecca Ahlstrand, Magni Gudmundsson, Alex de Leon, Stefan Lundin

01.12.2019 | Letter | Ausgabe 1/2019 Open Access

Benefits of red blood cell transfusion in patients with traumatic brain injury

Weimin Zhang, Kailei Du, Xuping Chen

01.12.2019 | Research | Ausgabe 1/2019 Open Access

Incidence and outcome of invasive candidiasis in intensive care units (ICUs) in Europe: results of the EUCANDICU project

Matteo Bassetti, Daniele R. Giacobbe, Antonio Vena, Cecilia Trucchi, Filippo Ansaldi, Massimo Antonelli, Vaclava Adamkova, Cristiano Alicino, Maria-Panagiota Almyroudi, Enora Atchade, Anna M. Azzini, Novella Carannante, Alessia Carnelutti, Silvia Corcione, Andrea Cortegiani, George Dimopoulos, Simon Dubler, José L. García-Garmendia, Massimo Girardis, Oliver A. Cornely, Stefano Ianniruberto, Bart Jan Kullberg, Katrien Lagrou, Clement Le Bihan, Roberto Luzzati, Manu L. N. G. Malbrain, Maria Merelli, Ana J. Marques, Ignacio Martin-Loeches, Alessio Mesini, José-Artur Paiva, Maddalena Peghin, Santi Maurizio Raineri, Riina Rautemaa-Richardson, Jeroen Schouten, Pierluigi Brugnaro, Herbert Spapen, Polychronis Tasioudis, Jean-François Timsit, Valentino Tisa, Mario Tumbarello, Charlotte H. S. B. van den Berg, Benoit Veber, Mario Venditti, Guillaume Voiriot, Joost Wauters, Philippe Montravers

01.12.2019 | Research | Ausgabe 1/2019 Open Access

Impact of weekly case-based tele-education on quality of care in a limited resource medical intensive care unit

Pedja Kovacevic, Sasa Dragic, Tijana Kovacevic, Danica Momcicevic, Emir Festic, Rahul Kashyap, Alexander S. Niven, Yue Dong, Ognjen Gajic

01.12.2019 | Viewpoint | Ausgabe 1/2019 Open Access

Videolaryngoscopy in critically ill patients

Samir Jaber, Audrey De Jong, Paolo Pelosi, Luca Cabrini, Jean Reignier, Jean Baptiste Lascarrou

01.12.2019 | Research | Ausgabe 1/2019 Open Access

The association between nutritional adequacy and 28-day mortality in the critically ill is not modified by their baseline nutritional status and disease severity

Charles Chin Han Lew, Gabriel Jun Yung Wong, Ka Po Cheung, Robert J. L. Fraser, Ai Ping Chua, Mary Foong Fong Chong, Michelle Miller

01.12.2019 | Letter | Ausgabe 1/2019 Open Access

Adopting a smart toothbrush with artificial intelligence may improve oral care in patients admitted to the intensive care unit

Tommaso Scquizzato, Arianna Gazzato

01.12.2019 | Research | Ausgabe 1/2019 Open Access

Beyond dichotomy: patterns and amplitudes of SSEPs and neurological outcomes after cardiac arrest

Sang Hoon Oh, Kyu Nam Park, Seung Pill Choi, Joo Suk Oh, Han Joon Kim, Chun Song Youn, Soo Hyun Kim, Kiyuk Chang, Seong Hoon Kim

01.12.2019 | Research | Ausgabe 1/2019 Open Access

Clinical use of [TIMP-2]•[IGFBP7] biomarker testing to assess risk of acute kidney injury in critical care: guidance from an expert panel

Louis M. Guzzi, Tobias Bergler, Brian Binnall, Daniel T. Engelman, Lui Forni, Michael J. Germain, Eric Gluck, Ivan Göcze, Michael Joannidis, Jay L. Koyner, V. Seenu Reddy, Thomas Rimmelé, Claudio Ronco, Julien Textoris, Alexander Zarbock, John A. Kellum

01.12.2019 | Letter | Ausgabe 1/2019 Open Access

Matrix metalloproteinase-8: a useful biomarker to refine the diagnosis of community-acquired pneumonia upon intensive care unit admission?

Fabrice Uhel, Brendon P. Scicluna, Lonneke A. van Vught, Olaf L. Cremer, Marc J. Bonten, Marcus J. Schultz, Tom van der Poll

01.12.2019 | Research | Ausgabe 1/2019 Open Access

Interventions aimed at healthcare professionals to increase the number of organ donors: a systematic review

Marloes Witjes, Nichon E. Jansen, Johannes G. van der Hoeven, Wilson F. Abdo

01.12.2019 | Letter | Ausgabe 1/2019 Open Access

Attainment of therapeutic vancomycin level within the first 24 h

Patrick M. Honore, David De Bels, Rachid Attou, Sebastien Redant, Andrea Gallerani, Kianoush Kashani

01.12.2019 | Letter | Ausgabe 1/2019 Open Access

New-onset QT prolongation is a novel predictor of mortality in critically ill patients

Yonghe Ding, Ryounghoon Jeon, Linyu Ran, Wenzhi Pan, Feilong Wang, Qiang Li

01.12.2019 | Research | Ausgabe 1/2019 Open Access

Prognostic value of NT-proBNP levels in the acute phase of sepsis on lower long-term physical function and muscle strength in sepsis survivors

Carlo Custodero, Quran Wu, Gabriela L. Ghita, Stephen D. Anton, Scott C. Brakenridge, Babette A. Brumback, Philip A. Efron, Anna K. Gardner, Christiaan Leeuwenburgh, Lyle L. Moldawer, John W. Petersen, Frederick A. Moore, Robert T. Mankowski

01.12.2019 | Letter | Ausgabe 1/2019 Open Access

Individualized recombinant human thrombomodulin (ART-123) administration in sepsis patients based on predicted phenotypes

Daisuke Hasegawa, Osamu Nishida

01.12.2019 | Research | Ausgabe 1/2019 Open Access

Hemodynamic goal-directed therapy and postoperative kidney injury: an updated meta-analysis with trial sequential analysis

Mariateresa Giglio, Lidia Dalfino, Filomena Puntillo, Nicola Brienza

01.12.2019 | Letter | Ausgabe 1/2019 Open Access

Is interleukin-8 a true predictor of pediatric acute respiratory distress syndrome outcomes? Beware of potential confounders

Sébastien Redant, François Angoulvant, Oceane Barbance, David De Bels, Andrea Gallerani, Rachid Attou, Kianoush Kashani, Patrick M. Honore

01.12.2019 | Research | Ausgabe 1/2019 Open Access

Alterations of the iNKT cell compartment in brain-injured patients

Allan Patinec, Jézabel Rocher, Mickael Vourc’h, Antoine Roquilly, Karim Asehnoune, Jacques Le Pendu

01.12.2019 | Research | Ausgabe 1/2019 Open Access

Plasma receptor interacting protein kinase-3 levels are associated with acute respiratory distress syndrome in sepsis and trauma: a cohort study

Michael G. S. Shashaty, John P. Reilly, Hilary E. Faust, Caitlin M. Forker, Caroline A. G. Ittner, Peggy X. Zhang, Meghan J. Hotz, David Fitzgerald, Wei Yang, Brian J. Anderson, Daniel N. Holena, Paul N. Lanken, Jason D. Christie, Nuala J. Meyer, Nilam S. Mangalmurti

01.12.2019 | Research | Ausgabe 1/2019 Open Access

Adipose tissue protects against sepsis-induced muscle weakness in mice: from lipolysis to ketones

Chloë Goossens, Ruben Weckx, Sarah Derde, Thomas Dufour, Sarah Vander Perre, Lies Pauwels, Steven E. Thiessen, Paul P. Van Veldhoven, Greet Van den Berghe, Lies Langouche

01.12.2019 | Editorial | Ausgabe 1/2019 Open Access

Pre-hospital plasma transfusion: a valuable coagulation support or an expensive fluid therapy?

Christian Fenger-Eriksen, Dietmar Fries, Jean-Stephane David, Pierre Bouzat, Marcus Daniel Lance, Oliver Grottke, Donat R. Spahn, Herbert Schoechl, Marc Maegele

01.12.2019 | Letter | Ausgabe 1/2019 Open Access

The hospital frailty risk score is of limited value in intensive care unit patients

Raphael Romano Bruno, Bernhard Wernly, Hans Flaatten, Fabian Schölzel, Malte Kelm, Christian Jung

01.12.2019 | Letter | Ausgabe 1/2019 Open Access

Adsorption and caspofungin dosing during continuous renal replacement therapy

Patrick M. Honore, David De Bels, Rachid Attou, Sebastien Redant, Andrea Gallerani, Kianoush Kashani

01.12.2019 | Research | Ausgabe 1/2019 Open Access

Trends in sepsis mortality over time in randomised sepsis trials: a systematic literature review and meta-analysis of mortality in the control arm, 2002–2016

Robert Luhr, Yang Cao, Bo Söderquist, Sara Cajander

01.12.2019 | Letter | Ausgabe 1/2019 Open Access

Need for expanded Candida Score for empiric antifungal use in medically critically ill patients?

Melanie E. Laine, Alexander H. Flannery, Breanna Moody, Melissa L. Thompson Bastin

01.12.2019 | Editorial | Ausgabe 1/2019 Open Access

How I manage intracranial hypertension

Chiara Robba, Giuseppe Citerio

01.12.2019 | Letter | Ausgabe 1/2019 Open Access

ECCCOing the call for emergency and critical care training in low middle-income countries

B. Jason Brotherton, Pete Halestrap, Evelyn Mbugua, Hannah Gitura, David Aliba, Jonathan E. Matson, Burton W. Lee

01.12.2019 | Research | Ausgabe 1/2019 Open Access

Effects of sedatives and opioids on trigger and cycling asynchronies throughout mechanical ventilation: an observational study in a large dataset from critically ill patients

Candelaria de Haro, Rudys Magrans, Josefina López-Aguilar, Jaume Montanyà, Enrico Lena, Carles Subirà, Sol Fernandez-Gonzalo, Gemma Gomà, Rafael Fernández, Guillermo M. Albaiceta, Yoanna Skrobik, Umberto Lucangelo, Gastón Murias, Ana Ochagavia, Robert M. Kacmarek, Montserrat Rue, Lluís Blanch, for the Asynchronies in the Intensive Care Unit (ASYNICU) Group

01.12.2019 | Commentary | Ausgabe 1/2019 Open Access

Neurological prognostication after cardiac arrest: how the “Best CPC” project would overcome selection biases

Marine Paul, Stéphane Legriel

01.12.2019 | Research | Ausgabe 1/2019 Open Access

Multimorbidity states associated with higher mortality rates in organ dysfunction and sepsis: a data-driven analysis in critical care

Zsolt Zador, Alexander Landry, Michael D. Cusimano, Nophar Geifman

01.12.2019 | Research | Ausgabe 1/2019 Open Access

Population pharmacokinetics of intravenous sufentanil in critically ill patients supported with extracorporeal membrane oxygenation therapy

Jongsung Hahn, Seungwon Yang, Kyoung Lok Min, Dasohm Kim, Byung Hak Jin, Changhun Park, Min Soo Park, Jin Wi, Min Jung Chang

01.12.2019 | Research | Ausgabe 1/2019 Open Access

Influence of contrast media on renal function and outcomes in patients with sepsis-associated acute kidney injury: a propensity-matched cohort study

Yuya Goto, Kansuke Koyama, Shinshu Katayama, Ken Tonai, Jun Shima, Toshitaka Koinuma, Shin Nunomiya

01.12.2019 | Research | Ausgabe 1/2019 Open Access

Health inequities in the diagnosis and outcome of sepsis in Argentina: a prospective cohort study

Elisa Estenssoro, Cecilia I. Loudet, Vanina S. K. Edul, Javier Osatnik, Fernando G. Ríos, Daniela N. Vásquez, Mario O. Pozo, Bernardo Lattanzio, Fernando Pálizas, Francisco Klein, Damián Piezny, Paolo N. Rubatto Birri, Graciela Tuhay, Anatilde Díaz, Analía Santamaría, Graciela Zakalik, Arnaldo Dubin, investigators of the SATISEPSIS Group

01.12.2019 | Research | Ausgabe 1/2019 Open Access

Comparative efficacy of linezolid and vancomycin for endotracheal tube MRSA biofilms from ICU patients

Laia Fernández-Barat, Ana Motos, Mauro Panigada, Francisco Álvarez-Lerma, Lucía Viña, Ruben Lopez-Aladid, Adrian Ceccato, Gianluigi Li Bassi, David P. Nicolau, Yuli Lopez, Laura Muñoz, Laura Guerrero, Dolors Soy, Trinidad Israel, Pedro Castro, Antoni Torres

01.12.2019 | Letter | Ausgabe 1/2019 Open Access

Decrease of the plasmatic endocan cleavage ratio is associated with the hyperinflammatory phenotype of acute respiratory distress syndrome

Alexandre Gaudet, Erika Parmentier, Nathalie De Freitas Caires, Lucie Portier, Sylvain Dubucquoi, Julien Poissy, Thibault Duburcq, Maxence Hureau, Philippe Lassalle, Daniel Mathieu

01.12.2019 | Research | Ausgabe 1/2019 Open Access

Lack of clinically relevant correlation between subjective and objective cognitive function in ICU survivors: a prospective 12-month follow-up study

Emily Brück, Jacob W. Larsson, Julie Lasselin, Matteo Bottai, Tatja Hirvikoski, Eva Sundman, Michael Eberhardson, Peter Sackey, Peder S. Olofsson

01.12.2019 | Research | Ausgabe 1/2019 Open Access

Interaction between low tidal volume ventilation strategy and severity of acute respiratory distress syndrome: a retrospective cohort study

Yanfei Shen, Guolong Cai, Shijin Gong, Lei Dong, Jing Yan, Wanru Cai

01.12.2019 | Correction | Ausgabe 1/2019 Open Access

Correction to: The early identification of disease progression in patients with suspected infection presenting to the emergency department: a multi-centre derivation and validation study

Kordo Saeed, Darius Cameron Wilson, Frank Bloos, Philipp Schuetz, Yuri van der Does, Olle Melander, Pierre Hausfater, Jacopo M. Legramante, Yann-Erick Claessens, Deveendra Amin, Mari Rosenqvist, Graham White, Beat Mueller, Maarten Limper, Carlota Clemente Callejo, Antonella Brandi, Marc-Alexis Macchi, Nicholas Cortes, Alexander Kutz, Peter Patka, María Cecilia Yañez, Sergio Bernardini, Nathalie Beau, Matthew Dryden, Eric C. M. van Gorp, Marilena Minieri, Louisa Chan, Pleunie P. M. Rood, Juan Gonzalez del Castillo

01.12.2019 | Research | Ausgabe 1/2019 Open Access

Recovery from acute kidney injury as a potent predictor of survival and good neurological outcome at discharge after out-of-hospital cardiac arrest

Yoo Seok Park, Yoon Hee Choi, Je Hyeok Oh, In Soo Cho, Kyoung-Chul Cha, Byung-Sun Choi, Je Sung You

01.12.2019 | Research | Ausgabe 1/2019 Open Access

Feasibility of myocardial perfusion assessment with contrast echocardiography: can it improve recognition of significant coronary artery disease in the ICU?

Sam Orde, Michel Slama, Faraz Pathan, Stephen Huang, Anthony Mclean

01.12.2019 | Review | Ausgabe 1/2019 Open Access

Influenza virus-related critical illness: pathophysiology and epidemiology

Andre C. Kalil, Paul G. Thomas

01.12.2019 | Research | Ausgabe 1/2019 Open Access

Intravenous fluid resuscitation is associated with septic endothelial glycocalyx degradation

Joseph A. Hippensteel, Ryo Uchimido, Patrick D. Tyler, Ryan C. Burke, Xiaorui Han, Fuming Zhang, Sarah A. McMurtry, James F. Colbert, Christopher J. Lindsell, Derek C. Angus, John A. Kellum, Donald M. Yealy, Robert J. Linhardt, Nathan I. Shapiro, Eric P. Schmidt

01.12.2019 | Research | Ausgabe 1/2019 Open Access

Association of sublingual microcirculation parameters and endothelial glycocalyx dimensions in resuscitated sepsis

Alexandros Rovas, Laura Mareen Seidel, Hans Vink, Timo Pohlkötter, Hermann Pavenstädt, Christian Ertmer, Michael Hessler, Philipp Kümpers

01.12.2019 | Research | Ausgabe 1/2019 Open Access

Abdominal functional electrical stimulation to assist ventilator weaning in critical illness: a double-blinded, randomised, sham-controlled pilot study

Euan J. McCaughey, Annemijn H. Jonkman, Claire L. Boswell-Ruys, Rachel A. McBain, Elizabeth A. Bye, Anna L. Hudson, David W. Collins, Leo M. A. Heunks, Angus J. McLachlan, Simon C. Gandevia, Jane E. Butler

01.12.2019 | Research | Ausgabe 1/2019 Open Access

Liberal versus restrictive red blood cell transfusion strategy in sepsis or septic shock: a systematic review and meta-analysis of randomized trials

Yohei Hirano, Yukari Miyoshi, Yutaka Kondo, Ken Okamoto, Hiroshi Tanaka

01.12.2019 | Research | Ausgabe 1/2019 Open Access

Sex-specific differences in survival after out-of-hospital cardiac arrest: a nationwide, population-based observational study

Yoshikazu Goto, Akira Funada, Tetsuo Maeda, Hirofumi Okada, Yumiko Goto

01.12.2019 | Research | Ausgabe 1/2019 Open Access

Functional hemodynamic tests: a systematic review and a metanalysis on the reliability of the end-expiratory occlusion test and of the mini-fluid challenge in predicting fluid responsiveness

Antonio Messina, Antonio Dell’Anna, Marta Baggiani, Flavia Torrini, Gian Marco Maresca, Victoria Bennett, Laura Saderi, Giovanni Sotgiu, Massimo Antonelli, Maurizio Cecconi

01.12.2019 | Letter | Ausgabe 1/2019 Open Access

Vitamin C administration in the critically ill: a summary of recent meta-analyses

Anitra C. Carr

01.12.2019 | Review | Ausgabe 1/2019 Open Access

Limb ischemia in peripheral veno-arterial extracorporeal membrane oxygenation: a narrative review of incidence, prevention, monitoring, and treatment

Eleonora Bonicolini, Gennaro Martucci, Jorik Simons, Giuseppe M. Raffa, Cristina Spina, Valeria Lo Coco, Antonio Arcadipane, Michele Pilato, Roberto Lorusso

01.12.2019 | Research | Ausgabe 1/2019 Open Access

Vitamin A deficiency in critically ill children with sepsis

Xuepeng Zhang, Kaiying Yang, Linwen Chen, Xuelian Liao, Liping Deng, Siyuan Chen, Yi Ji

01.12.2019 | Letter | Ausgabe 1/2019 Open Access

Mottling reduction in the early phases of profound septic shock

Daniel Taylor, Duncan Wyncoll

01.12.2019 | Review | Ausgabe 1/2019 Open Access

Functions and regulation of lipocalin-2 in gut-origin sepsis: a narrative review

Fanglin Lu, Kei Inoue, Jungo Kato, Shizuka Minamishima, Hiroshi Morisaki

01.12.2019 | Research | Ausgabe 1/2019 Open Access

The soluble mannose receptor (sMR/sCD206) in critically ill patients with invasive fungal infections, bacterial infections or non-infectious inflammation: a secondary analysis of the EPaNIC RCT

Greet De Vlieger, Ilse Vanhorebeek, Pieter J. Wouters, Inge Derese, Michael P. Casaer, Yves Debaveye, Greet Hermans, Philippe Meersseman, Holger J. Møller, Greet Van den Berghe, Catherine Ingels

01.12.2019 | Letter | Ausgabe 1/2019 Open Access

Combined assessment of ΔPCT and ΔCRP could increase the ability to differentiate candidemia from bacteremia

Qin Wu, Hao Yang, Yan Kang

01.12.2019 | Editorial | Ausgabe 1/2019 Open Access

Is this patient really “(un)stable”? How to describe cardiovascular dynamics in critically ill patients

Jean-Louis Vincent, Maurizio Cecconi, Bernd Saugel

01.12.2019 | Editorial | Ausgabe 1/2019 Open Access

Harmful effects of mechanical ventilation on neurocognitive functions

Federico Bilotta, Giovanni Giordano, Paola Giuseppina Sergi, Francesco Pugliese

01.12.2019 | Editorial | Ausgabe 1/2019 Open Access

The end-expiratory occlusion test: please, let me hold your breath!

Francesco Gavelli, Jean-Louis Teboul, Xavier Monnet

01.12.2019 | Letter | Ausgabe 1/2019 Open Access

Veno-venous ECMO indications: more than respiratory support

Aaron Blandino Ortiz, David Cabestrero Alonso, Raúl De Pablo Sánchez

01.12.2019 | Research | Ausgabe 1/2019 Open Access

Screening for posttraumatic stress disorder in ARDS survivors: validation of the Impact of Event Scale-6 (IES-6)

Megan M. Hosey, Jeannie-Marie S. Leoutsakos, Ximin Li, Victor D. Dinglas, O. Joseph Bienvenu, Ann M. Parker, Ramona O. Hopkins, Dale M. Needham, Karin J. Neufeld

01.12.2019 | Editorial | Ausgabe 1/2019 Open Access

Obituary Brian P. Kavanagh, MD

John C. Marshall, Arthur S. Slutsky

01.12.2019 | Research | Ausgabe 1/2019 Open Access

Interventions to prevent iatrogenic anemia: a Laboratory Medicine Best Practices systematic review

Nedra S. Whitehead, Laurina O. Williams, Sreelatha Meleth, Sara M. Kennedy, Nneka Ubaka-Blackmoore, Sharon M. Geaghan, James H. Nichols, Patrick Carroll, Michael T. McEvoy, Julie Gayken, Dennis J. Ernst, Christine Litwin, Paul Epner, Jennifer Taylor, Mark L. Graber

01.12.2019 | Research | Ausgabe 1/2019 Open Access

A deep learning model for real-time mortality prediction in critically ill children

Soo Yeon Kim, Saehoon Kim, Joongbum Cho, Young Suh Kim, In Suk Sol, Youngchul Sung, Inhyeok Cho, Minseop Park, Haerin Jang, Yoon Hee Kim, Kyung Won Kim, Myung Hyun Sohn

01.12.2019 | Review | Ausgabe 1/2019 Open Access

Thrombomodulin in disseminated intravascular coagulation and other critical conditions—a multi-faceted anticoagulant protein with therapeutic potential

Takashi Ito, Jecko Thachil, Hidesaku Asakura, Jerrold H. Levy, Toshiaki Iba

01.12.2019 | Research | Ausgabe 1/2019 Open Access

Capillary refill time variation induced by passive leg raising predicts capillary refill time response to volume expansion

Matthias Jacquet-Lagrèze, Nourredine Bouhamri, Philippe Portran, Rémi Schweizer, Florent Baudin, Marc Lilot, William Fornier, Jean-Luc Fellahi

01.12.2019 | Research | Ausgabe 1/2019 Open Access

Machine learning versus physicians’ prediction of acute kidney injury in critically ill adults: a prospective evaluation of the AKIpredictor

Marine Flechet, Stefano Falini, Claudia Bonetti, Fabian Güiza, Miet Schetz, Greet Van den Berghe, Geert Meyfroidt

01.12.2019 | Research | Ausgabe 1/2019 Open Access

Biomarker profiles of coagulopathy and alveolar epithelial injury in acute respiratory distress syndrome with idiopathic/immune-related disease or common direct risk factors

Kansuke Koyama, Shinshu Katayama, Ken Tonai, Jun Shima, Toshitaka Koinuma, Shin Nunomiya

01.12.2019 | Research | Ausgabe 1/2019 Open Access

Use of machine learning to analyse routinely collected intensive care unit data: a systematic review

Duncan Shillan, Jonathan A. C. Sterne, Alan Champneys, Ben Gibbison

01.12.2019 | Research | Ausgabe 1/2019 Open Access

Effect of different methods of cooling for targeted temperature management on outcome after cardiac arrest: a systematic review and meta-analysis

Lorenzo Calabró, Wulfran Bougouin, Alain Cariou, Chiara De Fazio, Markus Skrifvars, Eldar Soreide, Jacques Creteur, Hans Kirkegaard, Stéphane Legriel, Jean-Baptiste Lascarrou, Bruno Megarbane, Nicolas Deye, Fabio Silvio Taccone

01.12.2019 | Research | Ausgabe 1/2019 Open Access

Outcomes of hospitalized hematologic oncology patients receiving rapid response system activation for acute deterioration

Benjamin Gershkovich, Shannon M. Fernando, Brent Herritt, Lana A. Castellucci, Bram Rochwerg, Laveena Munshi, Sangeeta Mehta, Andrew J. E. Seely, Daniel I. McIsaac, Alexandre Tran, Peter M. Reardon, Peter Tanuseputro, Kwadwo Kyeremanteng

01.12.2019 | Letter | Ausgabe 1/2019 Open Access

How I manage ICP-CPP: a visual, yet individualized approach

William D. Freeman

01.12.2019 | Research | Ausgabe 1/2019 Open Access

Quantitative lung ultrasonography: a putative new algorithm for automatic detection and quantification of B-lines

Claudia Brusasco, Gregorio Santori, Elisa Bruzzo, Rosella Trò, Chiara Robba, Guido Tavazzi, Fabio Guarracino, Francesco Forfori, Patrizia Boccacci, Francesco Corradi

01.12.2019 | Letter | Ausgabe 1/2019 Open Access

Icatibant, another piece of the therapeutic puzzle regarding hemodynamic side effects of angiotensin-converting enzyme inhibitors

Patrick M. Honore, David De Bels, Leonel Barreto Gutierrez, Sebastien Redant, Andrea Gallerani, Willem Boer

01.12.2019 | Research | Ausgabe 1/2019 Open Access

Interleukin-26 is overexpressed in human sepsis and contributes to inflammation, organ injury, and mortality in murine sepsis

Hongmei Tu, Xiaofei Lai, Jiaxi Li, Lili Huang, Yi Liu, Ju Cao

01.12.2019 | Research | Ausgabe 1/2019 Open Access

Effect of dementia on the incidence, short-term outcomes, and resource utilization of invasive mechanical ventilation in the elderly: a nationwide population-based study

Carmen Bouza, Gonzalo Martínez-Alés, Teresa López-Cuadrado

01.12.2019 | Research | Ausgabe 1/2019 Open Access

Exploring the microvascular impact of red blood cell transfusion in intensive care unit patients

Geoffroy Hariri, Simon Bourcier, Zora Marjanovic, Jérémie Joffre, Jérémie Lemarié, Jean-Rémi Lavillegrand, Dominique Charue, Thomas Duflot, Naïke Bigé, Jean-Luc Baudel, Eric Maury, Mohamad Mohty, Bertrand Guidet, Jeremy Bellien, Olivier Blanc-Brude, Hafid Ait-Oufella

01.12.2019 | Research | Ausgabe 1/2019 Open Access

Impact of post-sepsis cardiovascular complications on mortality in sepsis survivors: a population-based study

Meng-Huan Wu, Po-Yang Tsou, Yu-Hsun Wang, Meng-tse Gabriel Lee, Christin Chih Ting Chao, Wan-Chien Lee, Si-Huei Lee, Jiun-Ruey Hu, Jiunn-Yih Wu, Shy-Shin Chang, Chien-Chang Lee

01.12.2019 | Letter | Ausgabe 1/2019 Open Access

Confounding factors for the effect of misdiagnosis of site of infection on in-hospital mortality

Kei Suzuki, Shinichiro Ohshimo, Nobuaki Shime

01.12.2019 | Letter | Ausgabe 1/2019 Open Access

Feedback function for capillary refilling time measurement device

Masayoshi Shinozaki, Taka-aki Nakada, Rui Kawaguchi, Yuichiro Yoshimura, Toshiya Nakaguchi, Hideaki Haneishi, Shigeto Oda

01.12.2019 | Letter | Ausgabe 1/2019 Open Access

Endocan is a reliable biomarker during continuous renal replacement therapy

Maxence Hureau, Alexandre Gaudet, Nathalie De Freitas Caires, Erika Parmentier, Julien Poissy, Thibault Duburcq, Philippe Lassalle, Daniel Mathieu

01.12.2019 | Letter | Ausgabe 1/2019 Open Access

Endotoxin removal by polymyxin B: is it a question of dose or duration or both?

Patrick M. Honore, David De Bels, Leonel Barreto Gutierrez, Sebastien Redant, Andrea Gallerani, Willem Boer

01.12.2019 | Research | Ausgabe 1/2019 Open Access

The association between premorbid beta blocker exposure and mortality in sepsis—a systematic review

Kaiquan Tan, Martin Harazim, Benjamin Tang, Anthony Mclean, Marek Nalos

01.12.2019 | Letter | Ausgabe 1/2019 Open Access

Time-based capnography detects ineffective triggering in mechanically ventilated children

Robert G. T. Blokpoel, Alette A. Koopman, Jefta van Dijk, Frans H. C. de Jongh, Johannes G. M. Burgerhof, Martin C. J. Kneyber

01.12.2019 | Research | Ausgabe 1/2019 Open Access

A multicenter RCT of noninvasive ventilation in pneumonia-induced early mild acute respiratory distress syndrome

Hangyong He, Bing Sun, Lirong Liang, Yanming Li, He Wang, Luqing Wei, Guofeng Li, Shuliang Guo, Jun Duan, Yuping Li, Ying Zhou, Yusheng Chen, Hongru Li, Jingping Yang, Xiyuan Xu, Liqiang Song, Jie Chen, Yong Bao, Feng Chen, Ping Wang, Lixi Ji, Yongxiang Zhang, Yanyan Ding, Liangan Chen, Ying Wang, Lan Yang, Tian Yang, Heng Weng, Hongyan Li, Daoxin Wang, Jin Tong, Yongchang Sun, Ran Li, Faguang Jin, Chunmei Li, Bei He, Lina Sun, Changzheng Wang, Mingdong Hu, Xiaohong Yang, Qin Luo, Jin Zhang, Hai Tan, Chen Wang, for the ENIVA Study Group

01.12.2019 | Research | Ausgabe 1/2019 Open Access

Co-administration of iloprost and eptifibatide in septic shock (CO-ILEPSS)—a randomised, controlled, double-blind investigator-initiated trial investigating safety and efficacy

Rasmus Ehrenfried Berthelsen, Sisse Rye Ostrowski, Morten Heiberg Bestle, Per Ingemar Johansson

01.12.2019 | Letter | Ausgabe 1/2019 Open Access

Recombinant human soluble thrombomodulin in patients with sepsis-associated coagulopathy (SCARLET): an updated meta-analysis

Kazuma Yamakawa, Jerrold H. Levy, Toshiaki Iba

01.12.2019 | Review | Ausgabe 1/2019 Open Access

Host susceptibility to severe influenza A virus infection

Sara Clohisey, John Kenneth Baillie

01.12.2019 | Letter | Ausgabe 1/2019 Open Access

Sevoflurane and nephrogenic diabetes insipidus on the rise: copeptin to the rescue?

Patrick M. Honore, David De Bels, Leonel Barreto Gutierrez, Sebastien Redant, Andrea Gallerani, Willem Boer

01.12.2019 | Letter | Ausgabe 1/2019 Open Access

Neuromuscular blocking agents for acute respiratory distress syndrome: how did we get conflicting results?

Heather Torbic, Sudhir Krishnan, Abhijit Duggal

01.12.2019 | Research | Ausgabe 1/2019 Open Access

Center effect in intubation risk in critically ill immunocompromised patients with acute hypoxemic respiratory failure

Guillaume Dumas, Alexandre Demoule, Djamel Mokart, Virginie Lemiale, Saad Nseir, Laurent Argaud, Frédéric Pène, Loay Kontar, Fabrice Bruneel, Kada Klouche, François Barbier, Jean Reignier, Annabelle Stoclin, Guillaume Louis, Jean-Michel Constantin, Florent Wallet, Achille Kouatchet, Vincent Peigne, Pierre Perez, Christophe Girault, Samir Jaber, Yves Cohen, Martine Nyunga, Nicolas Terzi, Lila Bouadma, Christine Lebert, Alexandre Lautrette, Naike Bigé, Jean-Herlé Raphalen, Laurent Papazian, Dominique Benoit, Michael Darmon, Sylvie Chevret, Elie Azoulay

01.12.2019 | Research | Ausgabe 1/2019 Open Access

Impact of species and antibiotic therapy of enterococcal peritonitis on 30-day mortality in critical care—an analysis of the OUTCOMEREA database

Anne-Cécile Morvan, Baptiste Hengy, Maïté Garrouste-Orgeas, Stéphane Ruckly, Jean-Marie Forel, Laurent Argaud, Thomas Rimmelé, Jean-Pierre Bedos, Elie Azoulay, Claire Dupuis, Bruno Mourvillier, Carole Schwebel, Jean-François Timsit, On behalf of the OUTCOMEREA study group

01.12.2019 | Research | Ausgabe 1/2019 Open Access

Differential contractile response of critically ill patients to neuromuscular electrical stimulation

Julius J. Grunow, Moritz Goll, Niklas M. Carbon, Max E. Liebl, Steffen Weber-Carstens, Tobias Wollersheim

01.12.2019 | Research | Ausgabe 1/2019 Open Access

Transfusion practice in the non-bleeding critically ill: an international online survey—the TRACE survey

Sanne de Bruin, Thomas W. L. Scheeren, Jan Bakker, Robin van Bruggen, Alexander P. J. Vlaar, on behalf of the Cardiovascular Dynamics Section and Transfusion Guideline Task Force of the ESICM

01.12.2019 | Letter | Ausgabe 1/2019 Open Access

SEA-mulation: training for technical treatment related to emergency situations in maritime environment

Brice Loddé, Gael-Emgan Querellou, Alexandre Morel, Erwan L’Her

01.12.2019 | Research | Ausgabe 1/2019 Open Access

Relationship of mottling score, skin microcirculatory perfusion indices and biomarkers of endothelial dysfunction in patients with septic shock: an observational study

Sigita Kazune, Anastasija Caica, Karina Volceka, Olegs Suba, Uldis Rubins, Andris Grabovskis

01.12.2019 | Research | Ausgabe 1/2019 Open Access

Comparison of echocardiographic indices of right ventricular systolic function and ejection fraction obtained with continuous thermodilution in critically ill patients

Romain Barthélémy, Xavier Roy, Tujia Javanainen, Alexandre Mebazaa, Benjamin Glenn Chousterman

01.12.2019 | Letter | Ausgabe 1/2019 Open Access

What is the best core measure after critical illness when the IES-R is no longer accessible for new researchers?

Reba Umberger

01.12.2019 | Letter | Ausgabe 1/2019 Open Access

Candida bloodstream infection under veno-arterial ECMO therapy

Quentin de Roux, Françoise Botterel, Raphaël Lepeule, Fabio Silvio Taccone, Olivier Langeron, Nicolas Mongardon

01.12.2019 | Letter | Ausgabe 1/2019 Open Access

Letter by Neugebauer et al. regarding article “Hypothermia after decompressive hemicraniectomy in treatment of malignant middle cerebral artery stroke: comment on the randomized clinical trial”

Hermann Neugebauer, Hauke Schneider, Rainer Kollmar

01.12.2019 | Editorial | Ausgabe 1/2019 Open Access

How I wean patients from veno-venous extra-corporeal membrane oxygenation

Francesco Vasques, Federica Romitti, Luciano Gattinoni, Luigi Camporota

01.12.2019 | Research | Ausgabe 1/2019 Open Access

Hemoadsorption with CytoSorb shows a decreased observed versus expected 28-day all-cause mortality in ICU patients with septic shock: a propensity-score-weighted retrospective study

Willem Pieter Brouwer, Servet Duran, Martijn Kuijper, Can Ince

01.12.2019 | Review | Ausgabe 1/2019 Open Access

Metabolic support in the critically ill: a consensus of 19

Jan Wernerman, Kenneth B. Christopher, Djillali Annane, Michael P. Casaer, Craig M. Coopersmith, Adam M. Deane, Elisabeth De Waele, Gunnar Elke, Carole Ichai, Constantine J. Karvellas, Stephen A. McClave, Heleen M. Oudemans-van Straaten, Olav Rooyackers, Renee D. Stapleton, Jukka Takala, Arthur R. H. van Zanten, Paul E. Wischmeyer, Jean-Charles Preiser, Jean-Louis Vincent

01.12.2019 | Research | Ausgabe 1/2019 Open Access

Preoxygenation before intubation in adult patients with acute hypoxemic respiratory failure: a network meta-analysis of randomized trials

Ka Man Fong, Shek Yin Au, George Wing Yiu Ng

01.12.2019 | Research | Ausgabe 1/2019 Open Access

Epinephrine, inodilator, or no inotrope in venoarterial extracorporeal membrane oxygenation implantation: a single-center experience

Viviane Zotzmann, Jonathan Rilinger, Corinna N. Lang, Klaus Kaier, Christoph Benk, Daniel Duerschmied, Paul M. Biever, Christoph Bode, Tobias Wengenmayer, Dawid L. Staudacher

01.12.2019 | Research | Ausgabe 1/2019 Open Access

Myocardial ischemia during ventilator weaning: a prospective multicenter cohort study

Alexandre Bedet, Françoise Tomberli, Gwenael Prat, Pierre Bailly, Achille Kouatchet, Sater Mortaza, Emmanuel Vivier, Sylvene Rosselli, Larissa Lipskaia, Guillaume Carteaux, Keyvan Razazi, Armand Mekontso Dessap

01.12.2019 | Correction | Ausgabe 1/2019 Open Access

Correction to: Procalcitonin levels in candidemia versus bacteremia: a systematic review

Andrea Cortegiani, Giovanni Misseri, Mariachiara Ippolito, Matteo Bassetti, Antonino Giarratano, Ignacio Martin-Loeches, Sharon Einav

01.12.2019 | Research | Ausgabe 1/2019 Open Access

Early prognostication of neurological outcome by heart rate variability in adult patients with out-of-hospital sudden cardiac arrest

Hiroshi Endoh, Natuo Kamimura, Hiroyuki Honda, Masakazu Nitta

01.12.2019 | Research | Ausgabe 1/2019 Open Access

Rescue fecal microbiota transplantation for antibiotic-associated diarrhea in critically ill patients

Min Dai, Yafei Liu, Wei Chen, Heena Buch, Yi Shan, Liuhui Chang, Yong Bai, Chen Shen, Xiaoyin Zhang, Yufeng Huo, Dian Huang, Zhou Yang, Zhihang Hu, Xuwei He, Junyu Pan, Lili Hu, Xinfang Pan, Xiangtao Wu, Bin Deng, Zhifeng Li, Bota Cui, Faming Zhang

01.12.2019 | Correction | Ausgabe 1/2019 Open Access

Correction to: Tracheal intubation in critically ill patients: a comprehensive systematic review of randomized trials

Luca Cabrini, Giovanni Landoni, Martina Baiardo Redaelli, Omar Saleh, Carmine D. Votta, Evgeny Fominskiy, Alessandro Putzu, Cézar Daniel Snak de Souza, Massimo Antonelli, Rinaldo Bellomo, Paolo Pelosi, Alberto Zangrillo

01.12.2019 | Editorial | Ausgabe 1/2019 Open Access

How I optimize power to avoid VILI

John J. Marini

01.12.2019 | Review | Ausgabe 1/2019 Open Access

SSEP retains its value as predictor of poor outcome following cardiac arrest in the era of therapeutic hypothermia

Ted L. Rothstein

01.12.2019 | Research Letter | Ausgabe 1/2019 Open Access

Obesity inducing acute respiratory distress syndrome: we should choose the right population!

Patrick M. Honore, Leonel Barreto Gutierrez, Sebastien Redant, Keitiane Kaefer, Andrea Gallerani, David De Bels

01.12.2019 | Research | Ausgabe 1/2019 Open Access

The interactive effects of input and output on managing fluid balance in patients with acute kidney injury requiring continuous renal replacement therapy

Jong Hyun Jhee, Hye Ah Lee, Seonmi Kim, Youn Kyung Kee, Ji Eun Lee, Shina Lee, Seung-Jung Kim, Duk-Hee Kang, Kyu Bok Choi, Hyung Jung Oh, Dong-Ryeol Ryu

01.12.2019 | Letter | Ausgabe 1/2019 Open Access

Clinical significance of lymphocytopenia in patients hospitalized with pneumonia caused by influenza virus

Valeria Bellelli, Gabriella d’Ettorre, Luigi Celani, Cristian Borrazzo, Giancarlo Ceccarelli, Mario Venditti

01.12.2019 | Letter | Ausgabe 1/2019 Open Access

How levosimendan can improve renal function?

Patrick M. Honore, Leonel Barreto Gutierrez, Sebastien Redant, Keitiane Kaefer, Andrea Gallerani, David De Bels

01.12.2019 | Letter | Ausgabe 1/2019 Open Access

Positive cultures and clinical outcomes in septic patients: be aware of the influence from patient selection and the in-hospital confounders

Romain Jouffroy, Benoît Vivien

01.12.2019 | Letter | Ausgabe 1/2019 Open Access

Prognostic performance of age-adapted SOFA and qSOFA in septic children

Xuepeng Zhang, Xiying Gui, Kaiying Yang, Siyuan Chen, Yi Ji

01.12.2019 | Research | Ausgabe 1/2019 Open Access

Correlation between end-tidal carbon dioxide and the degree of compression of heart cavities measured by transthoracic echocardiography during cardiopulmonary resuscitation for out-of-hospital cardiac arrest

Roman Skulec, Petr Vojtisek, Vladimir Cerny

01.12.2019 | Research | Ausgabe 1/2019 Open Access

Biomarkers and clinical scores to identify patient populations at risk of delayed antibiotic administration or intensive care admission

Juan Gonzalez del Castillo, Darius Cameron Wilson, Carlota Clemente-Callejo, Francisco Román, Ignasi Bardés-Robles, Inmaculada Jiménez, Eva Orviz, Macarena Dastis-Arias, Begoña Espinosa, Fernando Tornero-Romero, Jordi Giol-Amich, Veronica González, Ferran Llopis-Roca, on behalf of the INFURG-SEMES investigators

01.12.2019 | Letter | Ausgabe 1/2019 Open Access

Comment upon “Time to epinephrine treatment is associated with the risk of mortality in children who achieve sustained ROSC after traumatic out-of-hospital cardiac arrest”

Benjamin Post, Dominic Peter Douglas Nielsen, Anil Visram

01.12.2019 | Review | Ausgabe 1/2019 Open Access

Preparing intensive care for the next pandemic influenza

Taylor Kain, Robert Fowler

01.12.2019 | Research | Ausgabe 1/2019 Open Access

Adaptive mechanical ventilation with automated minimization of mechanical power—a pilot randomized cross-over study

Tobias Becher, Anna Adelmeier, Inéz Frerichs, Norbert Weiler, Dirk Schädler

01.12.2019 | Letter | Ausgabe 1/2019 Open Access

What should be the best dialysis catheter lock in critically ill patients?

Patrick M. Honore, Leonel Barreto Gutierrez, Sebastien Redant, Keitiane Kaefer, Andrea Gallerani, David De Bels

01.12.2019 | Letter | Ausgabe 1/2019 Open Access

The place of dexmedetomidine light sedation in patients with acute brain injury

Simone Carelli, Gennaro De Pascale, Nicoletta Filetici, Maria Grazia Bocci, Gian Marco Maresca, Salvatore Lucio Cutuli, Cecilia Maria Pizzo, Giuseppe Bello, Luca Montini, Anselmo Caricato, Giorgio Conti, Massimo Antonelli

01.12.2019 | Letter | Ausgabe 1/2019 Open Access

NT-proBNP levels might predict outcomes in severe sepsis, but renal function cannot be ignored

Jiarong Ye, Qianrong Liang, Xiaotu Xi

01.12.2019 | Letter | Ausgabe 1/2019 Open Access

Intracranial hypertension and deep sedation

Guillermo Bugedo, César Santis

01.12.2019 | Letter | Ausgabe 1/2019 Open Access

Hemoadsorption efficacy for uncomplicated high-risk cardiac surgery

Sébastien Redant, Matthieu Legrand, Yael Langman, Alejandra Garcia Aguilar, François Angoulvant, Keitiane Kaefer, David De Bels, Rachid Attou, Kianoush Kashani, Patrick M. Honore

01.12.2019 | Letter | Ausgabe 1/2019 Open Access

High-flow nasal cannula oxygen therapy versus conventional oxygen therapy in patients after planned extubation

Meng-Si Luo, Guan-Jiang Huang, Lun Wu

01.12.2019 | Letter | Ausgabe 1/2019 Open Access

Caution should be taken when using electronic health record database

Lina Wang, Xiaoming Wu

01.12.2019 | Research | Ausgabe 1/2019 Open Access

A novel non-invasive method to detect excessively high respiratory effort and dynamic transpulmonary driving pressure during mechanical ventilation

Michele Bertoni, Irene Telias, Martin Urner, Michael Long, Lorenzo Del Sorbo, Eddy Fan, Christer Sinderby, Jennifer Beck, Ling Liu, Haibo Qiu, Jenna Wong, Arthur S. Slutsky, Niall D. Ferguson, Laurent J. Brochard, Ewan C. Goligher

01.12.2019 | Research | Ausgabe 1/2019 Open Access

Effect of tranexamic acid on mortality in patients with haemoptysis: a nationwide study

Takahiro Kinoshita, Hiroyuki Ohbe, Hiroki Matsui, Kiyohide Fushimi, Hiroshi Ogura, Hideo Yasunaga

01.12.2019 | Research | Ausgabe 1/2019 Open Access

Low-flow assessment of current ECMO/ECCO2R rotary blood pumps and the potential effect on hemocompatibility

Sascha Gross-Hardt, Felix Hesselmann, Jutta Arens, Ulrich Steinseifer, Leen Vercaemst, Wolfram Windisch, Daniel Brodie, Christian Karagiannidis

01.12.2019 | Editorial | Ausgabe 1/2019 Open Access

Obituary: Professor Claude Martin

Marc Leone, Jean-Louis Vincent

01.12.2019 | Research | Ausgabe 1/2019 Open Access

Effects of a swallowing and oral care intervention for patients following endotracheal extubation: a pre- and post-intervention study

Chung-Pei Wu, Yu-Juan Xu, Tyng-Guey Wang, Shih-Chi Ku, Ding-Cheng Chan, Jang-Jaer Lee, Yu-Chung Wei, Tzu-Yu Hsiao, Cheryl Chia-Hui Chen

01.12.2019 | Research | Ausgabe 1/2019 Open Access

Early lactate measurement is associated with better outcomes in septic patients with an elevated serum lactate level

Hui Chen, Chenyan Zhao, Yao Wei, Jun Jin

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