Open Access
01.12.2020 | Research
A novel urinary biomarker predicts 1-year mortality after discharge from intensive care
Esther Nkuipou-Kenfack, Agnieszka Latosinska, Wen-Yi Yang, Marie-Céline Fournier, Alice Blet, Blerim Mujaj, Lutgarde Thijs, Elodie Feliot, Etienne Gayat, Harald Mischak, Jan A. Staessen, Alexandre Mebazaa, Zhen-Yu Zhang, N. Deye, C. Fauvaux, A. Mebazaa, C. Damoisel, D. Payen, E. Azoulay, A. S. Moreau, L. Jacob, O. Marie, M. Wolf, R. Sonneville, R. Bronchard, I. Rennuit, C. Paugam, J. P. Mira, A. Cariou, A. Tesnières, N. Dufour, N. Anguel, L. Guérin, J. Duranteau, C. Ract, M. Leone, B. Pastène, T. Sharshar, A. Fayssoyl, J. L. Baudel, B. Guidet, Q. Lu, W. Jie Gu, N. Brechot, A. Combes, S. Jaber, A. Pradel, Y. Coisel, M. Conseil, A. Vieillard-Baron, L. Bodson, J. Y. Lefrant, L. Elotmani, A. Ayral, S. Lloret, S. Pily-Flouri, J. B. Pretalli, P. F. Laterre, V. Montiel, M. F. Dujardin, C. Berghe
Open Access
01.12.2020 | Research
Should the ultrasound probe replace your stethoscope? A SICS-I sub-study comparing lung ultrasound and pulmonary auscultation in the critically ill
Eline G. M. Cox, Geert Koster, Aidan Baron, Thomas Kaufmann, Ruben J. Eck, T. Corien Veenstra, Bart Hiemstra, Adrian Wong, Thomas C. Kwee, Jaap E. Tulleken, Frederik Keus, Renske Wiersema, Iwan C. C. van der Horst, Geert Koster, Frederik Keus, Iwan C. C. van der Horst, Willem Dieperink, Roos Bleijendaal, Yasmin F. Cawale, Ramon P. Clement, Devon Dijkhuizen, Ruben J. Eck, Bart Hiemstra, Anja Haker, Casper D. H. Hilbink, Thomas Kaufmann, Martiene Klasen, Manon Klaver, Laura J. Schokking, Victor W. Sikkens, Madelon Vos, Justin Woerlee, Renske Wiersema
Open Access
01.12.2020 | Research
New-onset atrial fibrillation and associated outcomes and resource use among critically ill adults—a multicenter retrospective cohort study
Shannon M. Fernando, Rebecca Mathew, Benjamin Hibbert, Bram Rochwerg, Laveena Munshi, Allan J. Walkey, Morten Hylander Møller, Trevor Simard, Pietro Di Santo, F. Daniel Ramirez, Peter Tanuseputro, Kwadwo Kyeremanteng
Open Access
01.12.2020 | Research
Systematic assessment of fluid responsiveness during early septic shock resuscitation: secondary analysis of the ANDROMEDA-SHOCK trial
Eduardo Kattan, Gustavo A. Ospina-Tascón, Jean-Louis Teboul, Ricardo Castro, Maurizio Cecconi, Giorgio Ferri, Jan Bakker, Glenn Hernández, Glenn Hernandez, Gustavo Ospina-Tascón, Lucas Petri Damiani, Elisa Estenssoro, Arnaldo Dubin, Javier Hurtado, Gilberto Friedman, Ricardo Castro, Leyla Alegría, Jean-Louis Teboul, Maurizio Cecconi, Giorgio Ferri, Manuel Jibaja, Ronald Pairumani, Paula Fernández, Diego Barahona, Alexandre Biasi Cavalcanti, Jan Bakker, Glenn Hernandez, Leyla Alegría, Giorgio Ferri, Nicolás Rodriguez, Patricia Holger, Natalia Soto, Mario Pozo, Jan Bakker, Deborah Cook, Jean-Louis Vincent, Bryan P. Kavanagh, Phil Dellinger, Wim Rietdijk
Open Access
01.12.2020 | Research
Effects of endovascular and surface cooling on resuscitation in patients with cardiac arrest and a comparison of effectiveness, stability, and safety: a systematic review and meta-analysis
Xueli Liao, Ziyu Zhou, Manhong Zhou, Hui Tang, Menglong Feng, Bujin Kou, Ni Zhu, Futuan Liao, Liaozhang Wu
Open Access
01.12.2020 | Research
Time to appropriate antibiotic therapy is a predictor of outcome in patients with bloodstream infection caused by KPC-producing Klebsiella pneumoniae
Marco Falcone, Matteo Bassetti, Giusy Tiseo, Cesira Giordano, Elia Nencini, Alessandro Russo, Elena Graziano, Enrico Tagliaferri, Alessandro Leonildi, Simona Barnini, Alessio Farcomeni, Francesco Menichetti
Open Access
01.12.2020 | Research
The impact of high frequency oscillatory ventilation on mortality in paediatric acute respiratory distress syndrome
Judith Ju-Ming Wong, Siqi Liu, Hongxing Dang, Nattachai Anantasit, Phuc Huu Phan, Suwannee Phumeetham, Suyun Qian, Jacqueline Soo May Ong, Chin Seng Gan, Yek Kee Chor, Rujipat Samransamruajkit, Tsee Foong Loh, Mengling Feng, Jan Hau Lee
Open Access
01.12.2020 | Research
Impact of a posttraumatic cerebral infarction on outcome in patients with TBI: the Italian multicenter cohort INCEPT study
Nicola Latronico, Simone Piva, Nazzareno Fagoni, Lorenzo Pinelli, Michele Frigerio, Davide Tintori, Maurizio Berardino, Andrea Bottazzi, Livio Carnevale, Tiziana Casalicchio, Carlo Alberto Castioni, Simona Cavallo, Davide Cerasti, Giuseppe Citerio, Marco Fontanella, Serena Galiberti, Alan Girardini, Paolo Gritti, Ornella Manara, Paolo Maremmani, Roberta Mazzani, Giuseppe Natalini, Mirko Patassini, Maria Elena Perna, Ilaria Pesaresi, Danila Katia Radolovich, Maurizio Saini, Roberto Stefini, Cosetta Minelli, Roberto Gasparotti, Francesco A. Rasulo
Open Access
01.12.2020 | Research
Real-time shear wave ultrasound elastography: a new tool for the evaluation of diaphragm and limb muscle stiffness in critically ill patients
Aurelien Flatres, Yassir Aarab, Stephanie Nougaret, Fanny Garnier, Romaric Larcher, Mathieu Amalric, Kada Klouche, Pascal Etienne, Gilles Subra, Samir Jaber, Nicolas Molinari, Stefan Matecki, Boris Jung
Open Access
01.12.2020 | Correction
Correction to: Predicting the clinical trajectory in critically ill patients with sepsis: a cohort study
Peter M. C. Klein Klouwenberg, Cristian Spitoni, Tom van der Poll, Marc J. Bonten, Olaf L. Cremer, Marcus J. Schultz, Janneke Horn, Brendon Scicluna, Maryse A. Wiewel, Jos F. Frencken, Kirsten van de Groep, Marlies E. Koster-Brouwer, David S.Y. Ong, Diana Verboom, Friso M. de Beer, Lieuwe D. J. Bos, Gerie J. Glas, Roosmarijn T. M. van Hooijdonk, Laura R. A. Schouten, Marleen Straat, Esther Witteveen, Luuk Wieske, Arie J. Hoogendijk, Mischa A. Huson, Lonneke A. van Vught
Open Access
01.12.2020 | Research
Angiotensin I and angiotensin II concentrations and their ratio in catecholamine-resistant vasodilatory shock
Rinaldo Bellomo, Richard G. Wunderink, Harold Szerlip, Shane W. English, Laurence W. Busse, Adam M. Deane, Ashish K. Khanna, Michael T. McCurdy, Marlies Ostermann, Paul J. Young, Damian R. Handisides, Lakhmir S. Chawla, George F. Tidmarsh, Timothy E. Albertson
Open Access
01.12.2020 | Research
Cathelicidin preserves intestinal barrier function in polymicrobial sepsis
Jeffery Ho, Hung Chan, Yonghao Liang, Xiaodong Liu, Lin Zhang, Qing Li, Yuchen Zhang, Judeng Zeng, Felix N. Ugwu, Idy H. T. Ho, Wei Hu, Johnny C. W. Yau, Sunny H. Wong, Wai Tat Wong, Lowell Ling, Chi H. Cho, Richard L. Gallo, Tony Gin, Gary Tse, Jun Yu, Matthew T. V. Chan, Czarina C. H. Leung, William K. K. Wu
Open Access
01.12.2020 | Research
Effects of very early start of norepinephrine in patients with septic shock: a propensity score-based analysis
Gustavo A. Ospina-Tascón, Glenn Hernandez, Ingrid Alvarez, Luis E. Calderón-Tapia, Ramiro Manzano-Nunez, Alvaro I. Sánchez-Ortiz, Egardo Quiñones, Juan E. Ruiz-Yucuma, José L. Aldana, Jean-Louis Teboul, Alexandre Biasi Cavalcanti, Daniel De Backer, Jan Bakker
Open Access
01.12.2020 | Research
Intrapulmonary concentrations of meropenem administered by continuous infusion in critically ill patients with nosocomial pneumonia: a randomized pharmacokinetic trial
Adela Benítez-Cano, Sonia Luque, Luisa Sorlí, Jesús Carazo, Isabel Ramos, Nuria Campillo, Víctor Curull, Albert Sánchez-Font, Carles Vilaplana, Juan P. Horcajada, Ramón Adalia, Silvia Bermejo, Enric Samsó, William Hope, Santiago Grau
Open Access
01.12.2020 | Research
International evidence-based guidelines on Point of Care Ultrasound (POCUS) for critically ill neonates and children issued by the POCUS Working Group of the European Society of Paediatric and Neonatal Intensive Care (ESPNIC)
Yogen Singh, Cecile Tissot, María V. Fraga, Nadya Yousef, Rafael Gonzalez Cortes, Jorge Lopez, Joan Sanchez-de-Toledo, Joe Brierley, Juan Mayordomo Colunga, Dusan Raffaj, Eduardo Da Cruz, Philippe Durand, Peter Kenderessy, Hans-Joerg Lang, Akira Nishisaki, Martin C. Kneyber, Pierre Tissieres, Thomas W. Conlon, Daniele De Luca
Open Access
01.12.2020 | Research
Pneumococcal purpura fulminans in asplenic or hyposplenic patients: a French multicenter exposed-unexposed retrospective cohort study
Damien Contou, Rémi Coudroy, Gwenhaël Colin, Jean-Marc Tadié, Martin Cour, Romain Sonneville, Armand Mekontso Dessap, Nicolas de Prost, Laurent Argaud, François Barbier, Amélie Bazire, Gaëtan Béduneau, Frédéric Bellec, Pascal Beuret, Pascal Blanc, Cédric Bruel, Christian Brun-Buisson, Gwenhaël Colin, Delphine Colling, Alexandre Conia, Rémi Coudroy, Martin Cour, Damien Contou, Fabrice Daviaud, Vincent Das, Jean Dellamonica, Nadège Demars, Stephan Ehrmann, Arnaud Galbois, Elodie Gelisse, Julien Grouille, Laurent Guérin, Emmanuel Guérot, Samir Jaber, Caroline Jannière, Sébastien Jochmans, Mathieu Jozwiak, Pierre Kalfon, Antoine Kimmoun, Alexandre Lautrette, Jérémie Lemarié, Charlène Le Moal, Christophe Lenclud, Nicolas Lerolle, Olivier Leroy, Antoine Marchalot, Bruno Mégarbane, Armand Mekontso Dessap, Etienne de Montmollin, Frédéric Pène, Claire Pichereau, Gaëtan Plantefève, Sébastien Préau, Gabriel Preda, Nicolas de Prost, Jean-Pierre Quenot, Sylvie Ricome, Damien Roux, Bertrand Sauneuf, Matthieu Schmidt, Guillaume Schnell, Romain Sonneville, Jean-Marc Tadié, Yacine Tandjaoui, Martial Tchir, Nicolas Terzi, Xavier Valette, Lara Zafrani, Benjamin Zuber
Open Access
01.12.2020 | Research Letter
Added value of serial bio-adrenomedullin measurement in addition to lactate for the prognosis of septic patients admitted to ICU
Alice Blet, Charles de Roquetaillade, Oliver Hartmann, Joachim Struck, Alexandre Mebazaa, Benjamin Glenn Chousterman, Pierre-François Laterre, Caroline Berghe, Marie-France Dujardin, Suzanne Renard, Xavier Wittebole, Christine Collienne, Diego Castanares Zapatero, Thierry Dugernier, Marco Vinetti, Nicolas de Schryver, Anne Thirifays, Jacques Mairesse, Vincent Huberlant, Hélène Petre, Isabelle Buelens, Pierre Henin, Hugues Trine, Yves Laurent, Loix Sébastien, Paul Geukens, Laurent Kehl, Bruno François, Philippe Vignon, Nicolas Pichon, Emmanuelle Begot, Anne-Laure Fedou, Catherine Chapellas, Antoine Galy, Nicolas Rodier, Ludmilla Baudrillart, Michelle Nouaille, Séverine Laleu, Claire Mancia, Thomas Daix, Paul Bourzeix, Isabelle Herafa, Anne-Aurore Duchambon, Jean Baptiste Lascarrou, Maud Fiancette, Gwenhael Colin, Matthieu Henry-Lagarrigue, Jean-Claude Lacherade, Christine Lebert, Laurent Martin-Levfèvre, Isabelle Vinatier, Aihem Yehia, Konstantinos Bachoumas, Aurélie Joret, Jean Reignier, Cécille Rousseau, Natacha Maquigneau, Yolaine Alcourt, Vanessa Erragne Zinzonni, Angélique Deschamps, Angelina Robert, Emmanuelle Mercier, Véronique Simeon-Vieules, Aurélie Aubrey, Christine Mabilat, Denis Garot, Stephan Ehrmann, Annick Legras, Youenn Jouan, Pierre François Dequin, Antoine Guillon, Laetitia Bodet-Contentin, Emmannuelle Rouve, Charlotte Salmon, Lysiane Brick, Stéphanie Massat, Arnaud Desachy, Marie Anne Fally, Laurence Robin, Christophe Cracco, Charles Lafon, Sylvie Calvat, Stéphane Rouleau, David Schnell, Sigismond Lasocki, Philippe Fesard, Damien Leblanc, Guillaume Bouhours, Claire Chassier, Mathieu Conte, Thomas Gaillard, Floriane Denou, Mathieu Kerymel, Marion Guyon, Anthéa Loiez, Stéphanie Lebreton, Ferhat Meziani, Hayat Allam, Samir Chenaf, Hassène Rahmani, Sarah Heenen, Christine Kummerlen, Xavier Delabranche, Alexandra Boivin, Raphaël Clere-Jehl, Yannick Rabouël, Julien Pottecher, Sophie Bayer, Catherine Metzger, Stéphane Hecketsweiler, Pierre Olivier Ludes, Hortense Besancenot, Nadia Dhif, Guy Freys, Jean-Marc Lessinger, Anne Launoy, Aude Ruimy, Alain Meyer, M. Szozot, Alexandre Mebazaa, Nicolas Deye, Etienne Gayat, Marie-Céline Fournier, Sarra Abroug, Badr Louadah, Elodie Feliot, Sebastian Voicu, Isabelle Malissin, Bruno Megarbane, Philippe Manivet, Gardianot Victori, Da Silva Kelly, Béatrice La Foucher, Valérie Pierre, Lamia Kerdjana, Thomas Beeken, Antoine Goury, Pierre Garcon, Samuel Gaugain, Benjamin Glenn Chousterman, Benjamin Huot, Romain Barthelemy, Benjamin Soyer, Laurent Jacob, Matthieu Legrand, Marie-Céline Fournier, Francine Bonnet, Chloé Legall, Haikel Oueslati, Alexandru Cupaciu, Philippe Manivet, Badr Louadah, Romain Sonneville, Sophie Letrou, Lila Bouadma, Bruno Mourvillier, Véronique Deiler, Eric Magalhaes, Mathilde Neuville, Jean-François Timsit, Aguila Radjou, Stéphane Gaudry, Emeline Dubief, Jonathan Messika, Béatrice La Combe, Damien Roux, Guillaume Berquier, Mohamed Laissi, Jean-Damien Ricard, Jean-Michel Constantin, Sebastien Perbet, Julie Delmas, Julien Pascal, Sophie Cayot, Renaud Guerin, Matthieu Jabaudon, Laurence Roszyk, Christine Rolhion, Justine Bourdier, Mathilde Lematte, Charlène Gouhier, Camille Verlhac, Thomas Godet, Sophiano Radji, Elodie Caumon, Sandrine Thibault, Nikolaus Marx, Tobias Schuerholz, Jessica Pezechk, Florian Feld, Christian Brülls, Thorben Beeker, Tim-Philipp Simon, Robert Deisz, Achim Schindler, Bianca Meier, Thorsten Janisch, Andreas Hohn, Dirk Schedler, Wolfgang Wetsch, Daniel Schröder, Andreas Meier-Hellmann, Alexander Lucht, Robert Henker, Magdalena Römmer, Torsten Meinig, Kai D. Zacharowski, Patrick Meybohm, Simone Lindau, Haitham Mutlak, Stefan Kluge, Grit Ringeis, Birgit Füllekrug, Brigitte Singer, Axel Nierhaus, Katrin Bangert, Geraldine de Heer, Daniel Frings, Valentin Fuhrmann, Jakob Müller, Jörg Schreiber, Barbara Sensen, Stephanie Siedler, Annekatrin Siewecke, Gerold Söffker, Dominic Wichmann, Mélanie Kerinn, Ulrich Jaschinski, Ilse Kreuser, Marlene Zanquila, Andreas Kortgen, Frank Bloos, Falk Gonnert, Daniel Thomas-Rüddel, Anja Haucke, Steffi Kolanos, Karina Knuhr Kohlberg, Petra Bloos, Katrin Schwope, Salvatore Di Somma, Marino Rossella, Veronica Russo, Santarelli Simona, Christopher Bartoli, Sylvia Navarin, Cristina Bongiovanni, Michela Orru, Daniela Quatrocchi, Giada Zoccoli, Antonella Varchetta, Massimo Antonelli, Gennaro de Pascale, Maria Sole Vallecoccia, Salvatore Lucio Cutuli, Valentina Digravio, Daniela Quattrochi, Sonia D’Arrigo, Filippo Elvino Leone, Bert Beishuizen, Martin Rinket, Natalie Border, Mariska Bos-Burgmeijer, Astrid Braad, S. Papendorp, Alexander Cornet, J. Vermeijden, Ronald J. Trof, Peter Pickkers, Marieke van de A, Helen Van Wezel, Leo Heunks, Natalie Border, Chantal Luijten-Arts, Astrid Hoedemaekers, Hans van der Hoeven, Noortje Roovers, Pleun Hemelaar
Open Access
01.12.2020 | Research
Effects of a national quality improvement program on ICUs in China: a controlled pre-post cohort study in 586 hospitals
Huaiwu He, Xudong Ma, Longxiang Su, Lu Wang, Yanhong Guo, Guangliang Shan, Hui Jing He, Xiang Zhou, Dawei Liu, Yun Long, Yupei Zhao, Shuyang Zhang
Open Access
01.12.2020 | Research
Efficacy, immunogenicity, and safety of IC43 recombinant Pseudomonas aeruginosa vaccine in mechanically ventilated intensive care patients—a randomized clinical trial
Christopher Adlbrecht, Raphael Wurm, Pieter Depuydt, Herbert Spapen, Jose A. Lorente, Thomas Staudinger, Jacques Creteur, Christian Zauner, Andreas Meier-Hellmann, Philipp Eller, Margot Vander Laenen, Zsolt Molnár, István Várkonyi, Bernhard Schaaf, Mária Héjja, Vladimír Šrámek, Hauke Schneider, Niranjan Kanesa-thasan, Susanne Eder-Lingelbach, Anton Klingler, Katrin Dubischar, Nina Wressnigg, Jordi Rello
Open Access
01.12.2020 | Research
Quality indicators for patients with traumatic brain injury in European intensive care units: a CENTER-TBI study
Jilske A. Huijben, Eveline J. A. Wiegers, Ari Ercole, Nicolette F. de Keizer, Andrew I. R. Maas, Ewout W. Steyerberg, Giuseppe Citerio, Lindsay Wilson, Suzanne Polinder, Daan Nieboer, David Menon, Hester F. Lingsma, Mathieu van der Jagt, Cecilia Åkerlund, Krisztina Amrein, Nada Andelic, Lasse Andreassen, Gérard Audibert, Philippe Azouvi, Maria Luisa Azzolini, Ronald Bartels, Ronny Beer, Bo-Michael Bellander, Habib Benali, Maurizio Berardino, Luigi Beretta, Erta Beqiri, Morten Blaabjerg, Stine Borgen Lund, Camilla Brorsson, Andras Buki, Manuel Cabeleira, Alessio Caccioppola, Emiliana Calappi, Maria Rosa Calvi, Peter Cameron, Guillermo Carbayo Lozano, Marco Carbonara, Ana M. Castaño-León, Simona Cavallo, Giorgio Chevallard, Arturo Chieregato, Mark Coburn, Jonathan Coles, Jamie D. Cooper, Marta Correia, Endre Czeiter, Marek Czosnyka, Claire Dahyot-Fizelier, Paul Dark, Véronique De Keyser, Vincent Degos, Francesco Della Corte, Hugo den Boogert, Bart Depreitere, Dula Dilvesi, Abhishek Dixit, Jens Dreier, Guy-Loup Dulière, Erzsébet Ezer, Martin Fabricius, Kelly Foks, Shirin Frisvold, Alex Furmanov, Damien Galanaud, Dashiell Gantner, Alexandre Ghuysen, Lelde Giga, Jagos Golubovic, Pedro A. Gomez, Francesca Grossi, Deepak Gupta, Iain Haitsma, Raimund Helbok, Eirik Helseth, Peter J. Hutchinson, Stefan Jankowski, Faye Johnson, Mladen Karan, Angelos G. Kolias, Daniel Kondziella, Evgenios Koraropoulos, Lars-Owe Koskinen, Noémi Kovács, Ana Kowark, Alfonso Lagares, Steven Laureys, Fiona Lecky, Didier Ledoux, Aurelie Lejeune, Roger Lightfoot, Alex Manara, Costanza Martino, Hugues Maréchal, Julia Mattern, Catherine McMahon, Tomas Menovsky, Benoit Misset, Visakh Muraleedharan, Lynnette Murray, Ancuta Negru, David Nelson, Virginia Newcombe, József Nyirádi, Fabrizio Ortolano, Jean-François Payen, Vincent Perlbarg, Paolo Persona, Wilco Peul, Anna Piippo-Karjalainen, Horia Ples, Inigo Pomposo, Jussi P. Posti, Louis Puybasset, Andreea Radoi, Arminas Ragauskas, Rahul Raj, Jonathan Rhodes, Sophie Richter, Saulius Rocka, Cecilie Roe, Olav Roise, Jeffrey V. Rosenfeld, Christina Rosenlund, Guy Rosenthal, Rolf Rossaint, Sandra Rossi, Juan Sahuquillo, Oddrun Sandrød, Oliver Sakowitz, Renan Sanchez-Porras, Kari Schirmer-Mikalsen, Rico Frederik Schou, Peter Smielewski, Abayomi Sorinola, Emmanuel Stamatakis, Nino Stocchetti, Nina Sundström, Riikka Takala, Viktória Tamás, Tomas Tamosuitis, Olli Tenovuo, Matt Thomas, Dick Tibboel, Christos Tolias, Tony Trapani, Cristina Maria Tudora, Peter Vajkoczy, Shirley Vallance, Egils Valeinis, Zoltán Vámos, Gregory Van der Steen, Jeroen T. J. M. van Dijck, Thomas A. van Essen, Roel P. J. van Wijk, Alessia Vargiolu, Emmanuel Vega, Anne Vik, Rimantas Vilcinis, Victor Volovici, Daphne Voormolen, Petar Vulekovic, Guy Williams, Stefan Winzeck, Stefan Wolf, Alexander Younsi, Frederick A. Zeiler, Agate Ziverte, Tommaso Zoerle, Hans Clusmann
Open Access
01.12.2020 | Correction
Correction to: Real-time shear wave ultrasound elastography: a new tool for the evaluation of diaphragm and limb muscle stiffness in critically ill patients
Aurelien Flatres, Yassir Aarab, Stephanie Nougaret, Fanny Garnier, Romaric Larcher, Mathieu Amalric, Kada Klouche, Pascal Etienne, Gilles Subra, Samir Jaber, Nicolas Molinari, Stefan Matecki, Boris Jung
Open Access
01.12.2020 | Research
Assisted mechanical ventilation promotes recovery of diaphragmatic thickness in critically ill patients: a prospective observational study
Alice Grassi, Daniela Ferlicca, Ermes Lupieri, Serena Calcinati, Silvia Francesconi, Vittoria Sala, Valentina Ormas, Elena Chiodaroli, Chiara Abbruzzese, Francesco Curto, Andrea Sanna, Massimo Zambon, Roberto Fumagalli, Giuseppe Foti, Giacomo Bellani
Open Access
01.12.2020 | Research
Impact of concomitant vasoactive treatment and mechanical left ventricular unloading in a porcine model of profound cardiogenic shock
Nanna L. J. Udesen, Ole K. L. Helgestad, Ann B. S. Banke, Peter H. Frederiksen, Jakob Josiassen, Lisette O. Jensen, Henrik Schmidt, Elazer R. Edelman, Brian Y. Chang, Hanne B. Ravn, Jacob E. Møller
Open Access
01.12.2020 | Research
Dynamic LTR retrotransposon transcriptome landscape in septic shock patients
Marine Mommert, Olivier Tabone, Audrey Guichard, Guy Oriol, Elisabeth Cerrato, Mélanie Denizot, Valérie Cheynet, Alexandre Pachot, Alain Lepape, Guillaume Monneret, Fabienne Venet, Karen Brengel-Pesce, Julien Textoris, François Mallet, Christine Alberti-Segui, Bernard Allaouchiche, Laurent Argaud, Frédéric Aubrun, Véronique Barbalat, Thomas Baudry, Julien Bohé, Marie-Angélique Cazalis, Elisabeth Cerrato, Martin Cour, Sylvie De La Salle, Benjamin Delwarde, Bernard Floccard, Arnaud Friggeri, Emmanuelle Gallet-Gorius, Christian Guillaume, Romain Hernu, Audrey Larue-Triolet, Alain Lepape, Guillaume Marcotte, Delphine Maucort-Boulch, Boris Meunier, Guillaume Monneret, Stéphane Morisset, Julie Mouillaux, Alexandre Pachot, Mathieu Page, Nathalie Panel, Estelle Peronnet, Vincent Piriou, Anne Portier, Marion Provent, Thomas Rimmelé, Marie Simon, Julien Textoris, Fabrice Thiolliere, Hélène Vallin, Fabienne Venet, André Boibieux, Julien Davidson, Laure Fayolle-PivoT, Julie Gatel, Charline Genin, Arnaud Gregoire, Alain Lepape, Anne-Claire Lukaszewicz, Guillaume Marcotte, Marie Matray, Delphine Maucort-Boulch, Guillaume Monneret, Nathalie Panel, Thomas Rimmele, Hélène Vallin, Fabienne Venet, Sophie Blein, Karen Brengel-Pesce, Elisabeth Cerrato, Valérie Cheynet, Emmanuelle Gallet-Gorius, Audrey Guichard, Camille Jourdan, Natacha Koenig, François Mallet, Boris Meunier, Virginie Moucadel, Marine Mommert, Guy Oriol, Alexandre Pachot, Claire Schrevel, Olivier Tabone, Julien Textoris, Javier Yugueros Marcos, Jérémie Becker, Frédéric Bequet, Yacine Bounab, Florian Brajon, Bertrand Canard, Muriel Collus, Nathalie Garcon, Irène Gorse, Cyril Guyard, Fabien Lavocat, Philippe Leissner, Karen Louis, Maxime Mistretta, Jeanne Moriniere, Yoann MouscaZ, Laura Noailles, Magali Perret, Frédéric Reynier, Cindy Riffaud, Mary-Luz Rol, Nicolas Sapay, Trang Tran, Christophe Vedrine, Christophe Carre, Pierre Cortez, Aymeric De Monfort, Karine Florin, Laurent Fraisse, Isabelle Fugier, Maïna L’Azou, Sandrine Payrard, Annick PELERAUX, Laurence Quemeneur, Andrew Griffiths, Stephanie Toetsch, Teri Ashton, Peter J. Gough, Scott B. Berger, David Gardiner, Iain Gillespie, Aidan Macnamara, Aparna Raychaudhuri, Rob Smylie, Lionel Tan, Craig Tipple
Open Access
01.12.2020 | Research
Risk factors for candidemia: a prospective matched case-control study
Julien Poissy, Lauro Damonti, Anne Bignon, Nina Khanna, Matthias Von Kietzell, Katia Boggian, Dionysios Neofytos, Fanny Vuotto, Valérie Coiteux, Florent Artru, Stephan Zimmerli, Jean-Luc Pagani, Thierry Calandra, Boualem Sendid, Daniel Poulain, Christian van Delden, Frédéric Lamoth, Oscar Marchetti, Pierre-Yves Bochud, J. D. Aubert, Ch. Berger, P.-Y. Bochud, K. Boggian, T. Calandra, A. Christe, A. Conen, C. Corti-Fragoso, P. Dutkowski, Ph. Eggimann, C. Garzoni, D. Goldenberger, N. Khanna, F. Lamoth, O. Marchetti, E. Marques Maggio, K. Mühlethaler, D. Neofytos, D. Sanglard, P. W. Schreiber, U. Schanz, C. van Delden, M. Von Kietzell, R. Zbinden, S. Zimmerli, F. Artru, A. Bignon, V. Coiteux, D. Deblauw, A. El Kalioubie, K. Faure, N. François, T. Galpérine, B. Guéry, E. Jaillette, E. Kipnis, D. Mathieu, C. Nilès, E. Parmentier-Decrucq, J. Poissy, D. Poulain, S. Préau, L. Rahmania, L. Robriquet, A. Rouzé, B. Sendid, E. Vega, B. Voisin, P. Weyrich
Open Access
01.12.2020 | Research
Renal replacement therapy is independently associated with a lower risk of death in patients with severe acute kidney injury treated with targeted temperature management after out-of-hospital cardiac arrest
Yoon Hee Choi, Dong Hoon Lee, Je Hyeok Oh, Jung Hee Wee, Tae Chang Jang, Seung Pill Choi, Kyu Nam Park, Seung Pill Choi, Kyu Nam Park, Minjung Kathy Chae, Won Young Kim, Byung Kook Lee, Dong Hoon Lee, Tae Chang Jang, Jae Hoon Lee, Yoon Hee Choi, Je Sung You, Young Hwan Lee, In Soo Cho, Su Jin Kim, Jong-Seok Lee, Yong Hwan Kim, Min Seob Sim, Jonghwan Shin, Yoo Seok Park, Hyung Jun Moon, Won Jung Jeong, Joo Suk Oh, Kyoung-Chul Cha
Open Access
01.12.2020 | Research
Factors associated with the development of septic shock in patients with candidemia: a post hoc analysis from two prospective cohorts
Matteo Bassetti, Antonio Vena, Marco Meroi, Celia Cardozo, Guillermo Cuervo, Daniele Roberto Giacobbe, Miguel Salavert, Paloma Merino, Francesca Gioia, Mario Fernández-Ruiz, Luis Eduardo López-Cortés, Benito Almirante, Laura Escolà-Vergé, Miguel Montejo, Manuela Aguilar-Guisado, Pedro Puerta-Alcalde, Mariona Tasias, Alba Ruiz-Gaitán, Fernando González, Mireia Puig-Asensio, Francesc Marco, Javier Pemán, Jesus Fortún, Jose Maria Aguado, Alejandro Soriano, Jordi Carratalá, Carolina Garcia-Vidal, Maricela Valerio, Assunta Sartor, Emilio Bouza, Patricia Muñoz
Open Access
01.12.2020 | Research
Hyperoxemia and excess oxygen use in early acute respiratory distress syndrome: insights from the LUNG SAFE study
Fabiana Madotto, Emanuele Rezoagli, Tài Pham, Marcello Schmidt, Bairbre McNicholas, Alessandro Protti, Rakshit Panwar, Giacomo Bellani, Eddy Fan, Frank van Haren, Laurent Brochard, John G. Laffey, Antonio Pesenti, John G. Laffey, Laurent Brochard, Andres Esteban, Luciano Gattinoni, Frank van Haren, Anders Larsson, Daniel F. McAuley, Marco Ranieri, Gordon Rubenfeld, B. Taylor Thompson, Hermann Wrigge, Arthur S. Slutsky, Fernando Rios, T. Sottiaux, P. Depuydt, Fredy S. Lora, Luciano Cesar Azevedo, Eddy Fan, Guillermo Bugedo, Haibo Qiu, Marcos Gonzalez, Juan Silesky, Vladimir Cerny, Jonas Nielsen, Manuel Jibaja, Tài Pham, Dimitrios Matamis, Jorge Luis Ranero, Pravin Amin, S. M. Hashemian, Kevin Clarkson, Giacomo Bellani, Kiyoyasu Kurahashi, Asisclo Villagomez, Amine Ali Zeggwagh, Leo M. Heunks, Jon Henrik Laake, Jose Emmanuel Palo, Antero do Vale Fernandes, Dorel Sandesc, Yaasen Arabi, Vesna Bumbasierevic, Nicolas Nin, Jose A. Lorente, Lise Piquilloud, Fekri Abroug, Daniel F. McAuley, Lia McNamee, Javier Hurtado, Ed Bajwa, Gabriel Démpaire, Uhc Mother Theresa, Hektor Sula, Lordian Nunci, Alma Cani, Villa Maria, Alan Zazu, Christian Dellera, Carolina S. Insaurralde, Risso V. Alejandro, Julio Daldin, Mauricio Vinzio, Ruben O. Fernandez, Luis P. Cardonnet, Lisandro R. Bettini, Mariano Carboni Bisso, Emilio M. Osman, Mariano G. Setten, Pablo Lovazzano, Javier Alvarez, Veronica Villar, Norberto C. Pozo, Nicolas Grubissich, Gustavo A. Plotnikow, Daniela N. Vasquez, Santiago Ilutovich, Norberto Tiribelli, Ariel Chena, Carlos A. Pellegrini, María G. Saenz, Elisa Estenssoro, Matias Brizuela, Hernan Gianinetto, Pablo E. Gomez, Valeria I. Cerrato, Marco G. Bezzi, Silvina A. Borello, Flavia A. Loiacono, Adriana M. Fernandez, Serena Knowles, Claire Reynolds, Deborah M. Inskip, Jennene J. Miller, Jing Kong, Christina Whitehead, Shailesh Bihari, Aylin Seven, Amanda Krstevski, Helen J. Rodgers, Rebecca T. Millar, Toni E. Mckenna, Irene M. Bailey, Gabrielle C. Hanlon, Anders Aneman, Joan M. Lynch, Raman Azad, John Neal, Paul W. Woods, Brigit L. Roberts, Mark R. Kol, Helen S. Wong, Katharina C. Riss, Thomas Staudinger, Xavier Wittebole, Caroline Berghe, Pierre A. Bulpa, Alain M. Dive, Rik Verstraete, Herve Lebbinck, Pieter Depuydt, Joris Vermassen, Philippe Meersseman, Helga Ceunen, Jonas I. Rosa, Daniel O. Beraldo, Claudio Piras, Adenilton M. Rampinelli, Antonio P. Nassar Jr, Sergio Mataloun, Marcelo Moock, Marlus M. Thompson, Claudio H. Gonçalves, Ana Carolina P. Antônio, Aline Ascoli, Rodrigo S. Biondi, Danielle C. Fontenele, Danielle Nobrega, Vanessa M. Sales, Suresh Shindhe, Dk Maizatul Aiman B. Pg Hj Ismail, John Laffey, Francois Beloncle, Kyle G. Davies, Rob Cirone, Venika Manoharan, Mehvish Ismail, Ewan C. Goligher, Mandeep Jassal, Erin Nishikawa, Areej Javeed, Gerard Curley, Nuttapol Rittayamai, Matteo Parotto, Niall D. Ferguson, Sangeeta Mehta, Jenny Knoll, Antoine Pronovost, Sergio Canestrini, Alejandro R. Bruhn, Patricio H. Garcia, Felipe A. Aliaga, Pamela A. Farías, Jacob S. Yumha, Claudia A. Ortiz, Javier E. Salas, Alejandro A. Saez, Luis D. Vega, Eduardo F. Labarca, Felipe T. Martinez, Nicolás G. Carreño, Pilar Lora, Haitao Liu, Ling Liu, Rui Tang, Xiaoming Luo, Youzhong An, Huiying Zhao, Yan Gao, Zhe Zhai, Zheng L. Ye, Wei Wang, Wenwen Li, Qingdong Li, Ruiqiang Zheng, Wenkui Yu, Juanhong Shen, Xinyu Li, Tao Yu, Weihua Lu, Ya Q. Wu, Xiao B. Huang, Zhenyang He, Yuanhua Lu, Hui Han, Fan Zhang, Renhua Sun, Hua X. Wang, Shu H. Qin, Bao H. Zhu, Jun Zhao, Jian Liu, Bin Li, Jing L. Liu, Fa C. Zhou, Qiong J. Li, Xing Y. Zhang, Zhou Li-Xin, Qiang Xin-Hua, Liangyan Jiang, Yuan N. Gao, Xian Y. Zhao, Yuan Y. Li, Xiao L. Li, Chunting Wang, Qingchun Yao, Rongguo Yu, Kai Chen, Huanzhang Shao, Bingyu Qin, Qing Q. Huang, Wei H. Zhu, Ai Y. Hang, Ma X. Hua, Yimin Li, Yonghao Xu, Yu D. Di, Long L. Ling, Tie H. Qin, Shou H. Wang, Junping Qin, Yi Han, Suming Zhou, Monica P. Vargas, Juan I. Silesky Jimenez, Manuel A. González Rojas, Jaime E. Solis-Quesada, Christian M. Ramirez-Alfaro, Jan Máca, Peter Sklienka, Jakob Gjedsted, Aage Christiansen, Boris G. Villamagua, Miguel Llano, Philippe Burtin, Gautier Buzancais, Pascal Beuret, Nicolas Pelletier, Satar Mortaza, Alain Mercat, Jonathan Chelly, Sébastien Jochmans, Nicolas Terzi, Cédric Daubin, Guillaume Carteaux, Nicolas de Prost, Jean-Daniel Chiche, Fabrice Daviaud, Tai Pham, Muriel Fartoukh, Guillaume Barberet, Jerome Biehler, Jean Dellamonica, Denis Doyen, Jean-Michel Arnal, Anais Briquet, Sami Hraiech, Laurent Papazian, Arnaud Follin, Damien Roux, Jonathan Messika, Evangelos Kalaitzis, Laurence Dangers, Alain Combes, Siu-Ming Au, Gaetan Béduneau, Dorothée Carpentier, Elie H. Zogheib, Herve Dupont, Sylvie Ricome, Francesco L. Santoli, Sebastien L. Besset, Philippe Michel, Bruno Gelée, Pierre-Eric Danin, Bernard Goubaux, Philippe J. Crova, Nga T. Phan, Frantz Berkelmans, Julio C. Badie, Romain Tapponnier, Josette Gally, Samy Khebbeb, Jean-Etienne Herbrecht, Francis Schneider, Pierre-Louis M. Declercq, Jean-Philippe Rigaud, Jacques Duranteau, Anatole Harrois, Russell Chabanne, Julien Marin, Charlene Bigot, Sandrine Thibault, Mohammed Ghazi, Messabi Boukhazna, Salem Ould Zein, Jack R. Richecoeur, Daniele M. Combaux, Fabien Grelon, Charlene Le Moal, Elise P. Sauvadet, Adrien Robine, Virginie Lemiale, Danielle Reuter, Martin Dres, Alexandre Demoule, Dany Goldgran-Toledano, Loredana Baboi, Claude Guérin, Ralph Lohner, Jens Kraßler, Susanne Schäfer, Kai D. Zacharowski, Patrick Meybohm, Andreas W. Reske, Philipp Simon, Hans-Bernd F. Hopf, Michael Schuetz, Thomas Baltus, Metaxia N. Papanikolaou, Theonymfi G. Papavasilopoulou, Giannis A. Zacharas, Vasilis Ourailogloy, Eleni K. Mouloudi, Eleni V. Massa, Eva O. Nagy, Electra E. Stamou, Ellada V. Kiourtzieva, Marina A. Oikonomou, Luis E. Avila, Cesar A. Cortez, Johanna E. Citalán, Sameer A. Jog, Safal D. Sable, Bhagyesh Shah, Mohan Gurjar, Arvind K. Baronia, Mohammedfaruk Memon, Radhakrishnan Muthuchellappan, Venkatapura J. Ramesh, Anitha Shenoy, Ramesh Unnikrishnan, Subhal B. Dixit, Rachana V. Rhayakar, Nagarajan Ramakrishnan, Vallish K. Bhardwaj, Heera L. Mahto, Sudha V. Sagar, Vijayanand Palaniswamy, Deeban Ganesan, Seyed Mohammadreza Hashemian, Hamidreza Jamaati, Farshad Heidari, Edel A. Meaney, Alistair Nichol, Karl M. Knapman, Donall O’Croinin, Eimhin S. Dunne, Dorothy M. Breen, Kevin P. Clarkson, Rola F. Jaafar, Rory Dwyer, Fahd Amir, Olaitan O. Ajetunmobi, Aogan C. O’Muircheartaigh, Colin S. Black, Nuala Treanor, Daniel V. Collins, Wahid Altaf, Gianluca Zani, Maurizio Fusari, Savino Spadaro, Carlo A. Volta, Romano Graziani, Barbara Brunettini, Salvatore Palmese, Paolo Formenti, Michele Umbrello, Andrea Lombardo, Elisabetta Pecci, Marco Botteri, Monica Savioli, Alessandro Protti, Alessia Mattei, Lorenzo Schiavoni, Andrea Tinnirello, Manuel Todeschini, Antonino Giarratano, Andrea Cortegiani, Sara Sher, Anna Rossi, Massimo M. Antonelli, Luca M. Montini, Paolo Casalena, Sergio Scafetti, Giovanna Panarello, Giovanna Occhipinti, Nicolò Patroniti, Matteo Pozzi, Roberto R. Biscione, Michela M. Poli, Ferdinando Raimondi, Daniela Albiero, Giulia Crapelli, Eduardo Beck, Vincenzo Pota, Vincenzo Schiavone, Alexandre Molin, Fabio Tarantino, Giacomo Monti, Elena Frati, Lucia Mirabella, Gilda Cinnella, Tommaso Fossali, Riccardo Colombo, Pierpaolo Terragni Ilaria Pattarino, Francesco Mojoli, Antonio Braschi, Erika E. Borotto, Andrea N. Cracchiolo, Daniela M. Palma, Francesco Raponi, Giuseppe Foti, Ettore R. Vascotto, Andrea Coppadoro, Luca Brazzi, Leda Floris, Giorgio A. Iotti, Aaron Venti, Osamu Yamaguchi, Shunsuke Takagi, Hiroki N. Maeyama, Eizo Watanabe, Yoshihiro Yamaji, Kazuyoshi Shimizu, Kyoko Shiozaki, Satoru Futami, Sekine Ryosuke, Koji Saito, Yoshinobu Kameyama, Keiko Ueno, Masayo Izawa, Nao Okuda, Hiroyuki Suzuki, Tomofumi Harasawa, Michitaka Nasu, Tadaaki Takada, Fumihito Ito, Shin - Nunomiya, Kansuke - Koyama, Toshikazu Abe, Kohkichi Andoh, Kohei Kusumoto, Akira Hirata, Akihiro Takaba, Hiroyasu Kimura, Shuhei Matsumoto, Ushio Higashijima, Hiroyuki Honda, Nobumasa Aoki, Hiroshi Imai, Yasuaki Ogino, Ichiko Mizuguchi, Kazuya Ichikado, Kenichi Nitta, Katsunori Mochizuki, Tomoaki Hashida, Hiroyuki Tanaka, Tomoyuki Nakamura, Daisuke Niimi, Takeshi Ueda, Yozo Kashiwa, Akinori Uchiyama, Olegs Sabelnikovs, Peteris Oss, Youssef Haddad, Kong Y. Liew, Silvio A. Ñamendys-Silva, Yves D. Jarquin-Badiola, Luis A. Sanchez-Hurtado, Saira S. Gomez-Flores, Maria C. Marin, Asisclo J. Villagomez, Jordana S. Lemus, Jonathan M. Fierro, Mavy Ramirez Cervantes, Francisco Javier Flores Mejia, Dulce Dector, Dulce M. Dector, Daniel R. Gonzalez, Claudia R. Estrella, Jorge R. Sanchez-Medina, Alvaro Ramirez-Gutierrez, Fernando G. George, Janet S. Aguirre, Juan A. Buensuseso, Manuel Poblano, Tarek Dendane, Hicham Balkhi, Mina Elkhayari, Nacer Samkaoui, Hanane Ezzouine, Abdellatif Benslama Mourad Amor, Wajdi Maazouzi, Nedim Cimic, Oliver Beck, Monique M. Bruns, Jeroen A. Schouten, Myra - Rinia, Monique Raaijmakers, Hellen M. Van Wezel, Serge J. Heines, Ulrich Strauch, Marc P. Buise, Fabienne D. Simonis, Marcus J. Schultz, Jennifer C. Goodson, Troy S. Browne, Leanlove Navarra, Anna Hunt, Robyn A. Hutchison, Mathew B. Bailey, Lynette Newby, Colin Mcarthur, Michael Kalkoff, Alex Mcleod, Jonathan Casement, Danielle J. Hacking, Finn H. Andersen, Merete S. Dolva, Jon H. Laake, Andreas Barratt-Due, Kim Andre L. Noremark, Eldar Søreide, Brit Å. Sjøbø, Anne B. Guttormsen, Hector H. Leon Yoshido, Ronald Zumaran Aguilar, Fredy A. Montes Oscanoa, Alain U. Alisasis, Joanne B. Robles, Rossini Abbie B. Pasanting-Lim, Beatriz C. Tan, Pawel Andruszkiewicz, Karina Jakubowska, Cristina M. Coxo, António M. Alvarez, Bruno S. Oliveira, Gustavo M. Montanha, Nelson C. Barros, Carlos S. Pereira, António M. Messias, Jorge M. Monteiro, Ana M. Araujo, Nuno T. Catorze, Susan M. Marum, Maria J. Bouw, Rui M. Gomes, Vania A. Brito, Silvia Castro, Joana M. Estilita, Filipa M. Barros, Isabel M. Serra, Aurelia M. Martinho, Dana R. Tomescu, Alexandra Marcu, Ovidiu H. Bedreag, Marius Papurica, Dan E. Corneci, Silvius Ioan Negoita, Evgeny Grigoriev, Alexey I. Gritsan, Andrey A. Gazenkampf, Ghaleb Almekhlafi, Mohamad M. Albarrak, Ghanem M. Mustafa, Khalid A. Maghrabi, Nawal Salahuddin, Tharwat M. Aisa, Ahmed S. Al Jabbary, Edgardo Tabhan, Yaseen M. Arabi, Olivia A. Trinidad, Hasan M. Al Dorzi, Edgardo E. Tabhan, Stefan Bolon, Oliver Smith, Jordi Mancebo, Hernan Aguirre-Bermeo, Juan C. Lopez-Delgado, Francisco Esteve, Gemma Rialp, Catalina Forteza, Candelaria De Haro, Antonio Artigas, Guillermo M. Albaiceta, Sara De Cima-Iglesias, Leticia Seoane-Quiroga, Alexandra Ceniceros-Barros, Antonio L. Ruiz-Aguilar, Luis M. Claraco-Vega, Juan Alfonso Soler, Maria del Carmen Lorente, Cecilia Hermosa, Federico Gordo, Miryam – Prieto-González, Juan B. López-Messa, Manuel P. Perez, Cesar P. Perez, Raquel Montoiro Allue, Ferran Roche-Campo, Marcos Ibañez-Santacruz, Susana - Temprano, Maria C. Pintado, Raul De Pablo, Pilar Ricart Aroa Gómez, Silvia Rodriguez Ruiz, Silvia Iglesias Moles, Mª. Teresa Jurado, Alfons Arizmendi, Enrique A. Piacentini, Nieves Franco, Teresa Honrubia, Meisy Perez Cheng, Elena Perez Losada, Javier - Blanco, Luis J. Yuste, Cecilia Carbayo-Gorriz, Francisca G. Cazorla-Barranquero, Javier G. Alonso, Rosa S. Alda, Ángela Algaba, Gonzalo Navarro, Enrique Cereijo, Esther Diaz-Rodriguez, Diego Pastor Marcos, Laura Alvarez Montero, Luis Herrera Para, Roberto Jimenez Sanchez, Miguel Angel Blasco Navalpotro, Ricardo Diaz Abad, Raquel Montiel Gonz á lez, D. á cil Parrilla Toribio, Alejandro G. Castro, Maria Jose D. Artiga, Oscar Penuelas, Tomas P. Roser, Moreno F. Olga, Elena Gallego Curto, Rocío Manzano Sánchez, Vallverdu P. Imma, Garcia M. Elisabet, Laura Claverias, Monica Magret, Ana M. Pellicer, Lucia L. Rodriguez, Jesús Sánchez-Ballesteros, Ángela González-Salamanca, Antonio G. Jimenez, Francisco P. Huerta, Juan Carlos J. Sotillo Diaz, Esther Bermejo Lopez, David D. Llinares Moya, Alec A. Tallet Alfonso, Palazon Sanchez Eugenio Luis, Palazon Sanchez Cesar, Sánchez I. Rafael, Corcoles G. Virgilio, Noelia N. Recio, Richard O. Adamsson, Christian C. Rylander, Bernhard Holzgraefe, Lars M. Broman, Joanna Wessbergh, Linnea Persson, Fredrik Schiöler, Hans Kedelv, Anna Oscarsson Tibblin, Henrik Appelberg, Lars Hedlund, Johan Helleberg, Karin E. Eriksson, Rita Glietsch, Niklas Larsson, Ingela Nygren, Silvia L. Nunes, Anna-Karin Morin, Thomas Kander, Anne Adolfsson, Hervé O. Zender, Corinne Leemann-Refondini, Souheil Elatrous, Slaheddine Bouchoucha, Imed Chouchene, Islem Ouanes, Asma Ben Souissi, Salma Kamoun, Oktay Demirkiran, Mustafa Aker, Emre Erbabacan, Ilkay Ceylan, Nermin Kelebek Girgin, Menekse Ozcelik, Necmettin Ünal, Basak Ceyda Meco, Onat O. Akyol, Suleyman S. Derman, Barry Kennedy, Ken Parhar, Latha Srinivasa, Danny McAuley, Phil Hopkins, Clare Mellis, Vivek Kakar, Dan Hadfield, Andre Vercueil, Kaushik Bhowmick, Sally K. Humphreys, Andrew Ferguson, Raymond Mckee, Ashok S. Raj, Danielle A. Fawkes, Philip Watt, Linda Twohey, Rajeev R. JhaMatthew Thomas, Alex Morton, Varsha Kadaba, Mark J. Smith, Anil P. Hormis, Santhana G. Kannan, Miriam Namih, Henrik Reschreiter, Julie Camsooksai, Alek Kumar, Szabolcs Rugonfalvi, Christopher Nutt, Orla O’Neill, Colette Seasman, Ged Dempsey, Christopher J. Scott, Helen E. Ellis, Stuart Mckechnie, Paula J. Hutton, Nora N. Di Tomasso, Michela N. Vitale, Ruth O. Griffin, Michael N. Dean, Julius H. Cranshaw, Emma L. Willett, Nicholas Ioannou, Sarah Gillis, Peter Csabi, Rosaleen Macfadyen, Heidi Dawson, Pieter D. Preez, Alexandra J. Williams, Owen Boyd, Laura Ortiz-Ruiz De Gordoa, Jon Bramall, Sophie Symmonds, Simon K. Chau, Tim Wenham, Tamas Szakmany, Piroska Toth-Tarsoly, Katie H. McCalman, Peter Alexander, Lorraine Stephenson, Thomas Collyer, Rhiannon Chapman, Raphael Cooper, Russell M. Allan, Malcolm Sim, David W. Wrathall, Donald A. Irvine, Kim S. Zantua, John C. Adams, Andrew J. Burtenshaw, Gareth P. Sellors, Ingeborg D. Welters, Karen E. Williams, Robert J. Hessell, Matthew G. Oldroyd, Ceri E. Battle, Suresh Pillai, Istvan Kajtor, Mageswaran Sivashanmugavel, Sinead C. O’Kane, Adrian Donnelly, Aniko D. Frigyik, Jon P. Careless, Martin M. May, Richard Stewart, T. John Trinder, Samantha J. Hagan, Matt P. Wise, Jade M. Cole, Caroline C. MacFie, Anna T. Dowling, Nicolás Nin, Edgardo Nuñez, Gustavo Pittini, Ruben Rodriguez, María C. Imperio, Cristina Santos, Ana G. França, Alejandro EBEID, Alberto Deicas, Carolina Serra, Aditya Uppalapati, Ghassan Kamel, Valerie M. Banner-Goodspeed, Jeremy R. Beitler, Satyanarayana Reddy Mukkera, Shreedhar Kulkarni, Jarone Lee, Tomaz Mesar, John O. Shinn 3rd, Dina Gomaa, Christopher Tainter, Dale J. Yeatts, Jessica Warren, Michael J. Lanspa, Russel R. Miller, Colin K. Grissom, Samuel M. Brown, Philippe R. Bauer, Ryan J. Gosselin, Barrett T. Kitch, Jason E. Cohen, Scott H. Beegle, Renaud M. Gueret, Aiman Tulaimat, Shazia Choudry, William Stigler, Hitesh Batra, Nidhi G. Huff, Keith D. Lamb, Trevor W. Oetting, Nicholas M. Mohr, Claine Judy, Shigeki Saito, Fayez M. Kheir, Fayez Kheir, Adam B. Schlichting, Angela Delsing, Daniel R. Crouch, Mary Elmasri, Dina Ismail, Kyle R. Dreyer, Thomas C. Blakeman, Rebecca M. Baron, Carolina Quintana Grijalba, Peter C. Hou, Raghu Seethala, Imo Aisiku, Galen Henderson, Gyorgy Frendl, Sen-Kuang Hou, Robert L. Owens, Ashley Schomer, Vesna Bumbasirevic, Bojan Jovanovic, Maja Surbatovic, Milic Veljovic
Open Access
01.12.2020 | Research Letter
Feasibility and safety of watershed detection by contrast-enhanced ultrasound in patients receiving peripheral venoarterial extracorporeal membrane oxygenation: a prospective observational study
Nina Buchtele, Thomas Staudinger, Michael Schwameis, Christian Schörgenhofer, Harald Herkner, Alexander Hermann, Gerhard Ruzicka, Christoph Weiser, Hans Domanovits, Alexander O. Spiel, Peter Schellongowski, Andja Bojic, Anne Merrelaar, Monika Schmid
Open Access
01.12.2020 | Research
Long-term survival and costs following extracorporeal membrane oxygenation in critically ill children—a population-based cohort study
Shannon M. Fernando, Danial Qureshi, Peter Tanuseputro, Sonny Dhanani, Anne-Marie Guerguerian, Sam D. Shemie, Robert Talarico, Eddy Fan, Laveena Munshi, Bram Rochwerg, Damon C. Scales, Daniel Brodie, Kednapa Thavorn, Kwadwo Kyeremanteng
Open Access
01.12.2020 | Research
Urinary cell cycle arrest biomarkers and chitinase 3-like protein 1 (CHI3L1) to detect acute kidney injury in the critically ill: a post hoc laboratory analysis on the FINNAKI cohort
Eric A. Hoste, Suvi T. Vaara, Jorien De Loor, Mikko Haapio, Lieve Nuytinck, Kristel Demeyere, Ville Pettilä, Evelyne Meyer, Raili Laru-Sompa, Anni Pulkkinen, Minna Saarelainen, Mikko Reilama, Sinikka Tolmunen, Ulla Rantalainen, Marja Miettinen, Markku Suvela, Katrine Pesola, Pekka Saastamoinen, Sirpa Kauppinen, Ville Pettilä, Kirsi-Maija Kaukonen, Anna-Maija Korhonen, Sara Nisula, Suvi Vaara, Raili Suojaranta-Ylinen, Leena Mildh, Mikko Haapio, Laura Nurminen, Sari Sutinen, Leena Pettilä, Helinä Laitinen, Heidi Syrjä, Kirsi Henttonen, Elina Lappi, Hillevi Boman, Tero Varpula, Päivi Porkka, Mirka Sivula, Mira Rahkonen, Anne Tsurkka, Taina Nieminen, Niina Pirttinen, Ari Alaspää, Ville Salanto, Hanna Juntunen, Teija Sanisalo, Ilkka Parviainen, Ari Uusaro, Esko Ruokonen, Stepani Bendel, Niina Rissanen, Maarit Lång, Sari Rahikainen, Saija Rissanen, Merja Ahonen, Elina Halonen, Eija Vaskelainen, Meri Pouk-kanen, Esa Lintula, Sirpa Suominen, Jorma Heikki-nen, Timo Lavander, Kirsi Heinonen, Anne-Mari Juopperi, Tadeusz Kaminski, Fiia Gäddnäs, Tuija Kuusela, Jane Roiko, Sari Karlsson, Matti Reinikainen, Tero Surakka, Helena Jyrkönen, Tanja Eiserbeck, Jaana Kallinen, Tero Ala-Kokko, Jouko Laurila, Sinikka Sälkiö, Vesa Lund, Päivi Tuominen, Pauliina Perkola, Riikka Tuominen, Marika Hietaranta, Satu Johansson, Seppo Hovilehto, Anne Kirsi, Pekka Tiainen, Tuija Myllärinen, Pirjo Leino, Anne Toropainen, Anne Kuitunen, Jyrki Tenhunen, Ilona Leppänen, Markus Levoranta, Sanna Hoppu, Jukka Sauranen, Atte Kukkurainen, Samuli Kortelainen, Simo Varila, Outi Inkinen, Niina Koivuviita, Jutta Kotamäki, Anu Laine, Simo-Pekka Koivisto, Raku Hautamäki, Maria Skinnar
Open Access
01.12.2020 | Research
Circulating dipeptidyl peptidase-3 at admission is associated with circulatory failure, acute kidney injury and death in severely ill burn patients
François Dépret, Juliette Amzallag, Adrien Pollina, Laure Fayolle-Pivot, Maxime Coutrot, Maïté Chaussard, Karine Santos, Oliver Hartmann, Marion Jully, Alexandre Fratani, Haikel Oueslati, Alexandru Cupaciu, Mourad Benyamina, Lucie Guillemet, Benjamin Deniau, Alexandre Mebazaa, Etienne Gayat, Boris Farny, Julien Textoris, Matthieu Legrand
Open Access
01.12.2020 | Research
The clinical relevance of oliguria in the critically ill patient: analysis of a large observational database
Jean-Louis Vincent, Andrew Ferguson, Peter Pickkers, Stephan M. Jakob, Ulrich Jaschinski, Ghaleb A. Almekhlafi, Marc Leone, Majid Mokhtari, Luis E. Fontes, Philippe R. Bauer, Yasser Sakr, Esmael Tomas, Eric Amisi Bibonge, Boubaker Charra, Mamoun Faroudy, Linda Doedens, Zane Farina, David Adler, Cecile Balkema, Adri Kok, Sami Alaya, Hedi Gharsallah, Dritan Muzha, Atanas Temelkov, Georgi Georgiev, Georgi Simeonov, Georgi Tsaryanski, Silvi Georgiev, Ali Seliman, Srdan Vrankovic, Zeljko Vucicevic, Ivan Gornik, Bruno Barsic, Ino Husedzinovic, Pavel Pavlik, Jan Manak, Eva Kieslichova, Radovan Turek, Michal Fischer, Radka Valkova, Lukas Dadak, Pavel Dostal, Jan Malaska, Roman Hajek, Alexandra Židková, Pavel Lavicka, Joel Starkopf, Zurab Kheladze, Mamuka Chkhaidze, Vakhtang Kaloiani, Laszlo Medve, Agnes Sarkany, Ildiko Kremer, Zsuzsa Marjanek, Peter Tamasi, Inga Krupnova, Indulis Vanags, Viesturs Liguts, Vidas Pilvinis, Saulius Vosylius, Gintautas Kekstas, Mindaugas Balciunas, Julia Kolbusz, Andrzej Kübler, Beata Mielczarek, Malgorzata Mikaszewska-Sokolewicz, Katarzyna Kotfis, Barbara Tamowicz, Wiktor Sulkowski, Piotr Smuszkiewicz, Andrzej Pihowicz, Ewa Trejnowska, Natalia Hagau, Daniela Filipescu, Gabriela Droc, Mary Nicoleta Lupu, Alexandru Nica, Radu Stoica, Dana Rodica Tomescu, Dacia Laurentia Constantinescu, Georgica M. Valcoreanu Zbaganu, Adriana Slavcovici, Vladmir Bagin, Dmitry Belsky, Shamil Palyutin, Sergey Shlyapnikov, D. Bikkulova, Alexey Gritsan, Gulyaeva Natalia, Evgeny Makarenko, Vladimir Kokhno, Alla Tolkach, Evgeny Kokarev, Boris Belotserkovskiy, Konstantin Zolotukhin, Vladimir Kulabukhov, Ljiljana Soskic, Ivan Palibrk, Radmilo Jankovic, Bojan Jovanovic, Milena Pandurovic, Vesna Bumbasirevic, Boris Uljarevic, Maja Surbatovic, Nebojsa Ladjevic, Garri Slobodianiuk, Viliam Sobona, Andrea Cikova, Andrea Gebhardtova, Cao Jun, Sun Yunbo, Jun Dong, Sui Feng, Meili Duan, Yuan Xu, Xiaoyan Xue, Tieying Gao, Xue Zhong Xing, Xin Zhao, Chao Hong Li, Gengxihua Gengxihua, Huiqiong Tan, Jingqing Xu, Li Jiang, Qin Tiehe, Qin Bingyu, Qindong Shi, Zheng Lv, Liping Zhang, Liu Jingtao, Zheng Zhen, Zheng Wang, Tie Hua Wang, Liu Yuhong, Qian Zhai, Ying Chen, Chunting Wang, Wei Jiang, Wang Ruilan, Youdai Chen, Huang Xiaobo, Huiqing Ge, Tang Yan, Cui Yuhui, Jiuzhi Zhang, Fu Jian-Hong, Hong Zhu, Feifei Huo, Yushan Wang, Chao Li, Ma Zhuang, Zengxiang Ma, Jian Sun, Liuqingyue Liuqingyue, Mingshi Yang, Jianbiao Meng, Shaolin Ma, Yan Kang, Li Yu, Qianyi Peng, Yu Wei, Wei Zhang, Renhua Sun, Alwin Yeung, Wing Lun Wan, K. Kai Cheuk Sin, Kar Lung Lee, Meri Wijanti, Untung Widodo, Halim Samsirun, Tantani Sugiman, Calcarina Wisudarti, Tinni T. Maskoen, Noritaka Hata, Yoshiro Kobe, Osamu Nishida, Dai Miyazaki, Shin Nunomiya, Shigehiko Uchino, Nobuya Kitamura, Koichi Yamashita, Satoru Hashimoto, Hidetada Fukushima, Nik Azman Nik Adib, Li Ling Tai, Bill Tony, Rodolfo Roman Bigornia, Rodolfo Roman Bigornia, Rodolfo Roman Bigornia, Jose Emmanuel Palo, Somnath Chatterjee, Bee Hong Tan, Andrew Kong, Shirley Goh, Chien-Chang Lee, Chaicharn Pothirat, Bodin Khwannimit, Pongdhep Theerawit, Prapaporn Pornsuriyasak, Annop Piriyapatsom, Ahmed Mukhtar, Ahmed Nabil Hamdy, Hisham Hosny, Ali Ashraf, Majid Mokhtari, Shiva Nowruzinia, Amir Hossein Lotfi, Farid Zand, Reza Nikandish, Omid Moradi Moghaddam, Jonathan Cohen, Oded Sold, Tacla Sfeir, Alaa Yasin Hasan, Dena Abugaber, Habib Ahmad, Tarek Tantawy, Salim Baharoom, Haifa Algethamy, Anas Amr, Ghaleb Almekhlafi, Ramazan Coskun, Murat Sungur, Ahmet Cosar, Bülent Güçyetmez, Oktay Demirkiran, Evren Senturk, Hulya Ulusoy, Hakan Korkut Atalan, Simay Serin, Ismail Kati, Zainab Alnassrawi, Ayesha Almemari, Kalpana Krishnareddy, Sayed Kashef, Asad Alsabbah, Germain Poirier, John C. Marshall, Margaret Herridge, Margaret Herridge, Rosangela Fernandez-Medero, Gerard Fulda, Sharon Banschbach, Juan Quintero, Elizabeth Schroeder, Corinna Sicoutris, Renaud Gueret, Rahul Kashyap, Philippe Bauer, Rahul Nanchal, Richard G. Wunderink, Edgar Jimenez, Andrea Ryan, Denvir Prince, John Edington, Frank Van Haren, Andrew Bersten, David J. Hawkins, Myrene Kilminster, David Sturgess, Marc Ziegenfuss, Stephanie O’ Connor, Jeffrey Lipman, Lewis Campbell, Rick Mcallister, Brigit Roberts, Patricia Williams, Rachael Parke, Patrick Seigne, Ross Freebairn, Daniel Nistor, Chantal Oxley, Paul Young, Ricardo Valentini, Nestor Wainsztein, Pablo Comignani, Maria Casaretto, Giselle Sutton, Paula Villegas, Cayerano Galletti, Jorge Neira, Daniel Rovira, Jorge Hidalgo, Freddy Sandi, Eliana Caser, Marlus M. Thompson, Mariza D’agostino Dias, Luis E. Fontes, Maria C. Lunardi, Nazah C. Youssef, Suzana Lobo, Ricardo Silva, Joao A. Sales Jr, Lina Madeira Campos Melo, Mirella Oliveira, Mariza Fonte, Cintia Grion, Carlos Feijo, Valaria Rezende, Murillo Assuncao, Ana P. Neves, Pablo Gusman, Dyanne Dalcomune, Cassiano Teixeira, Keitiane Kaefer, Israel Maia, Vicente Souza Dantas, Rubens Costa Filho, Fabio Amorim, Maria Assef, Paulo Schiavetto, Joao Houly, Fabiano Bianchi, Fernando Dias, Carla Avila, Leila Rego, Priscylla Castro, Joel Passos, Ciro Mendes, Cintia Grion, Giovana Colozza Mecatti, Marcia Ferrreira, Vivian Irineu, Marcio Guerreiro, Sebastian Ugarte, Vinko Tomicic, Christian Godoy, Wagner Samaniego, Ignacio Escamilla, Ignacio Escamilla, Luis F. Castro Castro, Giovanni Libreros Duque, Diego Diaz-Guio, Frederico Benítez, Arturo Guerra Urrego, Ricardo Buitrago, Guillermo Ortiz, Maria C. Villalba Gaviria, Donat Salas, Jorge Ramirez-Arce, Estuardo Salgado, Diego Morocho, Jose Vergara, Miguel Chung Sang, Carlos Orellana-Jimenez, Lorena Garrido, Oscar Diaz, Dabor Resiere, Carlos Osorio, Alberto De La Vega, Raul Carrillo, Victor Sanchez, Asisclo Villagomez, Ricardo Martinez Zubieta, Maria Sandia, Maycotte Zalatiel, Manuel Poblano, Daniel Rodriguez Gonzalez, Fernando Arrazola, Leal L. Juan Francisco, Silvio A. Ñamendys-Silva, Rosalinda Guerra Moya, Marco Hernandez, Diego M. Rodriguez Cadena, Ines Lopez Islas, Carlos M. Ballesteros Zarzavilla, Alfredo Matos, Indira Oyanguren, Jorge Cerna, Rosario Quispe Sierra, Rocio Jimenez, Luis Castillo, Ramizan Ocal, Atilla Sencan, Silvia M. Mareque Gianoni, Alberto Deicas, Javier Hurtado, Gaston Burghi, Antonio Martinelli, Ingrid Von Der Osten, Christine Du Maine, Mahuya Bhattacharyya, Susruta Bandyopadhyay, Srishar Yanamala, Palepu Gopal, Samir Sahu, Mohamed Ibrahim, Darshana Rathod, Nisha Mukundan, Arun Dewan, Pravin Amin, Srinivas Samavedam, Bhagyesh Shah, Ganavelu Gurupal, Brajendra Lahkar, Amit K. Mandal, Mrinal Sircar, Supradip Ghosh, Veluchamy Balasubramani, Farhad Kapadia, Sonali Vadi, Kesavan Nair, Swagat Tripathy, Sivakumar Nandakumar, Jeetendra Sharma, Arindam Kar, Simant Jha, Kapil Zirpe, Mayur Patel, Ankur Bhavsar, Devi P. Samaddar, Atul Kulkarni, Madiha Hashmi, Wajid Ali, Syed Nadeem, Kanishka Indraratna, Antoni Margarit, Philipp Urbanek, Joachim Schlieber, Johann Reisinger, Johann Auer, Andreas Hartjes, Andreas Lerche, Thomas Janous, Eveline Kink, Walter Krahulec, Karl-Heinz Smolle, Marc Van Der Schueren, Patrick Thibo, Marc Vanhoof, Ibis Ahmet, Philippe Gadisseux, Philippe Dufaye, Olivier Jacobs, Vincent Fraipont, Patrick Biston, Alain Dive, Yves Bouckaert, Eric Gilbert, Benjamin Gressens, Eric Pinck, Vincent Collin, Jean-Louis Vincent, Jan J. De Waele, Rocio Rimachi, Dan Gusu, Koen De Decker, Kakisidi Mandianga, Luc Heytens, Xavier Wittebole, Herbert Spapen, Olivier Van Collie, Wout Vandenheede, Peter Rogiers, Piotr Kolodzeike, Mary Kruse, Torben Andersen, Veli-Pekka Harjola, Kari Saarinen, Marc Leone, Alain Durocher, Serge Moulront, Alain Lepape, Marie-Reine Losser, Philippe Cabaret, Evangelos Kalaitzis, Elie Zogheib, Philippe Charve, Bruno François, Jean-Yves Lefrant, Bassam Beilouny, Xavier Forceville, Benoit Misset, Frederic Jacobs, Bernard Floccard, Didier Payen, Alain Wynckel, Vincent Castelain, Alexandre Faure, Pierre Lavagne, Thierry Lepoivre, Mouhamed D. Moussa, Antoine Vieillard-Baron, Michel Durand, Marc Gainnier, Carole Ichai, Stefan Arens, Clemens Hoffmann, Magnus Kaffarnik, Claus-Jorg Scharnofske, Ingo Voigt, Claus Peckelsen, Matthias Weber, Jochen Gille, Andreas Lange, Georg Schoser, Armin Sablotzki, Ulrich Jaschinski, Andreas Bluethgen, Frank Vogel, Andreas Tscheu, Thomas Fuchs, Michael Wattenberg, Torsten Helmes, Stefan Scieszka, Matthias Heintz, Samir Sakka, Johannes Kohler, Fritz Fiedler, Matthias Danz, Yasser Sakr, Reimer Riessen, Thomas Kerz, Alexander Kersten, Frank Tacke, Gernot Marx, Thomas Volkert, Axel Schmutz, Axel Nierhaus, Stefan Kluge, Peter Abel, Rolf A. Janosi, Stefan Utzolino, Hendrik Bracht, Susanne Toussaint, Maria Giannakou Peftoulidou, Pavlos Myrianthefs, Apostolos Armaganidis, Christina Routsi, Angela Xini, Eleni Mouloudi, Ioannis Kokoris, George Kyriazopoulos, Sawas Vlachos, Athena Lavrentieva, Panagio Partala, George Nakos, Alma Moller, Sigurjon Ö. Stefansson, Joan Barry, Ruth A. O’Leary, Catherine Motherway, Mohammad Faheem, Eimhin Dunne, Maria Donnelly, Torsten Konrad, Eleonora Bonora, Carola Achilli, Sandra Rossi, Giacomo Castiglione, Adriano Peris, Daniela Albanese, Nino Stocchetti, Giuseppe Citerio, Lorella Mozzoni, Erminio Sisillo, Pasquale De Negri, Monica Savioli, Pietro Vecchiarelli, Florin Puflea, Vladimir Stankovic, Giulio Minoja, Silvia Montibeller, Plinio Calligaro, Raffaella Sorrentino, Marco Feri, Massimo Zambon, Elena Colombaroli, Antonino Giarratano, Tommaso Pellis, Carlo Capra, Massimo Antonelli, Antonino Gullo, Cosimo Chelazzi, Antonella De Capraris, Nicolo Patroniti, Massimo Girardis, Frederico Franchi, Giorgio Berlot, Michael Buttigieg, Hubert Ponssen, Julia Ten Cate, Laura Bormans, Satria Husada, Marc Buise, Ben Van Der Hoven, Auke Reidinga, Michael Kuiper, Peter Pickkers, Georg Kluge, Sylvia Den Boer, Jozef Kesecioglu, Henk Van Leeuwen, Hans Flaatten, Skule Mo, Vitor Branco, Fernando Rua, Estevao Lafuente, Marta Sousa, Nuno Catorze, Maria Barros, Luis Pereira, Ana Vintém De Oliveira, Jose Gomes, Isable Gaspar, Maria F. Pereira, Maria Cymbron, Antonio Dias, Eduardo Almeida, Sofia Beirao, Isabel Serra, Rosa Ribeiro, Pedro Povoa, Filomena Faria, Zelia Costa-E-Silva, Jose J. Nóbrega, Fatima Fernandes, Joao Gabriel, Gorazd Voga, Erik Rupnik, Lucka Kosec, Milena Kerin Povšic, Irena Osojnik, Viktorija Tomic, Andreja Sinkovic, Javier González, Elizabeth Zavala, Jesus Pérez Valenzuela, Luis Marina, Pablo Vidal-Cortés, Pilar Posada, Ignacio Martin-Loeches, Noelia Muñoz Guillén, Mercedes Palomar, Jordi Sole-Violan, Antoni Torres, Miguel A. Gonzalez Gallego, Gerardo Aguilar, Raquel Montoiro Allué, Monica Argüeso, Martin Parejo, Manuel Palomo Navarro, Anton Jose, Nicholas Nin, Francisco Alvarez Lerma, Oscar Martinez, Eva Tenza Lozano, Sara Arenal López, Maria J. Perez Granda, Salvador Moreno, Clara Llubia, Carmen De La Fuente Martos, Paloma Gonzalez-Arenas, Noemi Llamas Fernández, Bernard Gil Rueda, Isabel Estruch Pons, Nieves Cruza, Fernando Maroto, Angel Estella, Ana Ferrer, Lisardo Iglesias Fraile, Brigida Quindos, Amaia Quintano, Maria T. Tebar, Pablo Cardinal, Antonio Reyes, Alejandro Rodríguez, Ana Abella, Santiago García Del Valle, Santiago Yus, Emilio Maseda, Jose A. Berezo, Armando Tejero Pedregosa, Clara Laplaza, Ricard Ferrer, Jesus Rico-Feijoo, Marina Rodríguez, Pablo Monedero, Karin Eriksson, Dan Lind, David Chabanel, Hervé Zender, Kuno Heer, Bernd Frankenberger, Stephan Jakob, Alois Haller, Shiju Matthew, Robert Downes, Casiano Barrera Groba, Andrew Johnston, Roseanne Meacher, Rick Keays, Philip Haji-Michael, Chris Tyler, Andrew Ferguson, Simon Jones, David Tyl, Andrew Ball, John Vogel, Malcolm Booth, Paul Downie, Malcolm Watters, Stephen Brett, Marc Garfield, Lynn Everett, Sarah Heenen, Sandeep Dhir, Zoe Beardow, Marthinus Mostert, Steve Brosnan, Nuno Pinto, Stephen Harris, Andy Summors, Andrew Norton, Alastair Rose, Rebecca Appelboam, Omubo Davies, Emma Vickers, Banwari Agarwal, Tamas Szakmany, Stephen Wimbush, Ingeborg Welters, Rupert Pearse, Robin Hollands, Justin Kirk-Bayley, Nick Fletcher, Barbara Bray, David Brealey, Peter Alexander, Steven Henderson, Chris Hargreaves, Heather Black, Kiran Gowda
Open Access
29.04.2020 | COVID-19 | Research Letter
Is a more aggressive COVID-19 case detection approach mitigating the burden on ICUs? Some reflections from Italy
Giulia Lorenzoni, Corrado Lanera, Danila Azzolina, Paola Berchialla, Dario Gregori, Dario Gregori, Corrado Lanera, Paola Berchialla, Dolores Catelan, Danila Azzolina, Ilaria Prosepe, Annibale Biggeri, Cristina Canova, Elisa Gallo, Francesco Garzotto, Giulia Lorenzoni, Nicolas Destro
Open Access
29.04.2020 | COVID-19 | Commentary
Shining a light on the evidence for hydroxychloroquine in SARS-CoV-2
Nicholas E. Ingraham, David Boulware, Matthew A. Sparks, Timothy Schacker, Bradley Benson, Jeffrey A. Sparks, Thomas Murray, John Connett, Jeffrey G. Chipman, Anthony Charles, Christopher J. Tignanelli
Open Access
01.12.2020 | Research
Copeptin as a marker of outcome after cardiac arrest: a sub-study of the TTM trial
Joachim Düring, Martin Annborn, Tobias Cronberg, Josef Dankiewicz, Yvan Devaux, Christian Hassager, Janneke Horn, Jesper Kjaergaard, Michael Kuiper, Homa Rafi Nikoukhah, Pascal Stammet, Johan Undén, Michael Jaeger Wanscher, Matt Wise, Hans Friberg, Niklas Nielsen
Open Access
01.12.2020 | Research
Clinical course and outcome of 107 patients infected with the novel coronavirus, SARS-CoV-2, discharged from two hospitals in Wuhan, China
Dawei Wang, Yimei Yin, Chang Hu, Xing Liu, Xingguo Zhang, Shuliang Zhou, Mingzhi Jian, Haibo Xu, John Prowle, Bo Hu, Yirong Li, Zhiyong Peng
Open Access
11.05.2020 | COVID-19 | Editorial
Our recommendations for acute management of COVID-19
Francesco Mojoli, Silvia Mongodi, Anita Orlando, Eric Arisi, Marco Pozzi, Luca Civardi, Guido Tavazzi, Fausto Baldanti, Raffaele Bruno, Giorgio Antonio Iotti, Carlo Marena, Monica Calvi, Giuseppina Grugnetti, Marco Maurelli, Alba Muzzi, Bruno Raffaele, Paolo Lago, Gianluigi Marseglia, Stefano Perlini, Alessandra Palo, Fausto Baldanti, Luigi Oltrona Visconti, Angelo Guido Corsico, Antonio Di Sabatino, Francesco Mojoli, Giorgio Iotti, Marco Benazzo, Nicora Carlo, Triarico Antonio, Petronella Vincenzo
Open Access
15.05.2020 | COVID-19 | Research
Patients with COVID-19 in 19 ICUs in Wuhan, China: a cross-sectional study
Yuan Yu, Dan Xu, Shouzhi Fu, Jun Zhang, Xiaobo Yang, Liang Xu, Jiqian Xu, Yongran Wu, Chaolin Huang, Yaqi Ouyang, Luyu Yang, Minghao Fang, Hongwen Xiao, Jing Ma, Wei Zhu, Song Hu, Quan Hu, Daoyin Ding, Ming Hu, Guochao Zhu, Weijiang Xu, Jun Guo, Jinglong Xu, Haitao Yuan, Bin Zhang, Zhui Yu, Dechang Chen, Shiying Yuan, You Shang
Open Access
01.12.2020 | Research
Neurally adjusted ventilatory assist versus pressure support ventilation: a randomized controlled feasibility trial performed in patients at risk of prolonged mechanical ventilation
Daniel J. Hadfield, Louise Rose, Fiona Reid, Victoria Cornelius, Nicholas Hart, Clare Finney, Bethany Penhaligon, Jasmine Molai, Clair Harris, Sian Saha, Harriet Noble, Emma Clarey, Leah Thompson, John Smith, Lucy Johnson, Phillip A. Hopkins, Gerrard F. Rafferty
Open Access
01.12.2020 | Research
Gastrointestinal dysfunction in the critically ill: a systematic scoping review and research agenda proposed by the Section of Metabolism, Endocrinology and Nutrition of the European Society of Intensive Care Medicine
Annika Reintam Blaser, Jean-Charles Preiser, Sonja Fruhwald, Alexander Wilmer, Jan Wernerman, Carina Benstoem, Michael P. Casaer, Joel Starkopf, Arthur van Zanten, Olav Rooyackers, Stephan M. Jakob, Cecilia I. Loudet, Danielle E. Bear, Gunnar Elke, Matthias Kott, Ingmar Lautenschläger, Jörn Schäper, Jan Gunst, Christian Stoppe, Leda Nobile, Valentin Fuhrmann, Mette M. Berger, Heleen M. Oudemans-van Straaten, Yaseen M. Arabi, Adam M. Deane, Annika Reintam Blaser, Jean-Charles Preiser, Sonja Fruhwald, Alexander Wilmer, Jan Wernerman, Carina Benstoem, Michael P. Casaer, Joel Starkopf, Arthur van Zanten, Olav Rooyackers, Stephan M. Jakob, Cecilia I. Loudet, Danielle E. Bear, Gunnar Elke, Matthias Kott, Ingmar Lautenschläger, Jörn Schäper, Jan Gunst, Christian Stoppe, Leda Nobile, Valentin Fuhrmann, Mette M. Berger, Heleen M. Oudemans-van Straaten, Yaseen M. Arabi, Adam M. Dean, Karin Amrein, Guillaume Besch, Brenno Belazi Nery de Souza Campos, Elisabeth De Waele, Vincent Fraipont, Teodoro Grau, Kursat Gundogan, Claudia Heidegger, Michael Hiesmayr, Carole Ichai, Mar Juan-Díaz, Kurt Kobke-Jacobsen, Vasiliki Koutsoukou, Marcus Laube, Juan Carlos Montejo González, Zudin Puthucheary, Anne-Francoise Rousseau, Pierre Singer, Sandra N. Stapel, Hakan Tekguc, Carlos Torruco-Sotelo
Open Access
18.05.2020 | COVID-19 | Research Letter
Angiotensin II infusion in COVID-19-associated vasodilatory shock: a case series
Alberto Zangrillo, Giovanni Landoni, Luigi Beretta, Federica Morselli, Ary Serpa Neto, Rinaldo Bellomo, Anna Mara Scandroglio, Sergio Colombo, Antonio Dell’Acqua, Paolo Silvani, Evgeny Fominskiy, Giacomo Monti, Maria Luisa Azzolini, Antonio Bellantoni, Cristina Barberio, Gabriele Valsecchi, Omar Saleh, Gaetano Lombardi, Moreno Tresoldi, Paolo Scarpellini, Lorenzo Dagna, Fabio Ciceri, Yanase Fumitaka
Open Access
01.12.2020 | Research
Severe diffuse alveolar hemorrhage related to autoimmune disease: a multicenter study
Adrien Mirouse, Antoine Parrot, Vincent Audigier, Alexandre Demoule, Julien Mayaux, Guillaume Géri, Eric Mariotte, Nicolas Bréchot, Nicolas de Prost, Mathieu Vautier, Mathilde Neuville, Naïke Bigé, Etienne de Montmollin, Patrice Cacoub, Matthieu Resche-Rigon, Jacques Cadranel, David Saadoun
Open Access
01.12.2020 | Research
Hemophagocytic lymphohistiocytosis in critically ill patients: diagnostic reliability of HLH-2004 criteria and HScore
Cornelia Knaak, Peter Nyvlt, Friederike S. Schuster, Claudia Spies, Patrick Heeren, Thomas Schenk, Felix Balzer, Paul La Rosée, Gritta Janka, Frank M. Brunkhorst, Didier Keh, Gunnar Lachmann
Open Access
27.05.2020 | COVID-19 | Research Letter
COVID-19 patients exhibit less pronounced immune suppression compared with bacterial septic shock patients
Matthijs Kox, Tim Frenzel, Jeroen Schouten, Frank L. van de Veerdonk, Hans J. P. M. Koenen, Peter Pickkers, Pleun Hemelaar, Remi Beunders, Johannes van der Hoeven, Sjef van der Velde, Hetty van der Eng, Noortje Rovers, Margreet Klop-Riehl, Jelle Gerretsen, Emma Kooistra, Nicole Waalders, Wout Claassen, Hidde Heesakkers, Tirsa van Schaik, Mihai Netea, Leo Joosten, Nico Janssen, Inge Grondman, Aline de Nooijer, Quirijn de Mast, Martin Jaeger, Ilse Kouijzer, Helga Dijkstra, Heidi Lemmers, Reinout van Crevel, Josephine van de Maat, Gerine Nijman, Simone Moorlag, Esther Taks, Priya Debisarun, Heiman Wertheim, Joost Hopman, Janette Rahamat-Langendoen, Chantal Bleeker-Rovers, Esther Fasse, Esther van Rijssen, Manon Kolkman, Bram van Cranenbroek, Ruben Smeets, Irma Joosten
Open Access
27.05.2020 | COVID-19 | Letter
Universal mobile protection system for aerosol-generating medical interventions in COVID-19 patients
Florian Straube, Clemens Wendtner, Ellen Hoffmann, S. Volz, U. Dorwarth, M. Engel, N. Schneider, J. Lärmer, B. Nagel, P. Friederich, R. Fisch, A. Riess, J. Benedikter, F. J. Meyer, B. Lewerenz, W. Schepp, M. Schmid, C. Dodt, W. Schmidt, K. Weidenbach, S. Rogowski, H. Kossmann, M. Berger, C. Gatos, B. Wuerstl, M. Deichstetter
Open Access
01.12.2020 | Research
Low-resolution pressure reactivity index and its derived optimal cerebral perfusion pressure in adult traumatic brain injury: a CENTER-TBI study
Lennart Riemann, Erta Beqiri, Peter Smielewski, Marek Czosnyka, Nino Stocchetti, Oliver Sakowitz, Klaus Zweckberger, Andreas Unterberg, Alexander Younsi, Audny Anke, Ronny Beer, Bo-Michael Bellander, Andras Buki, Giorgio Chevallard, Arturo Chieregato, Giuseppe Citerio, Endre Czeiter, Bart Depreitere, George Eapen, Shirin Frisvold, Raimund Helbok, Stefan Jankowski, Daniel Kondziella, Lars-Owe Koskinen, Geert Meyfroidt, Kirsten Moeller, David Nelson, Anna Piippo-Karjalainen, Andreea Radoi, Arminas Ragauskas, Rahul Raj, Jonathan Rhodes, Saulius Rocka, Rolf Rossaint, Juan Sahuquillo, Ana Stevanovic, Nina Sundström, Riikka Takala, Tomas Tamosuitis, Olli Tenovuo, Peter Vajkoczy, Alessia Vargiolu, Rimantas Vilcinis, Stefan Wolf
Open Access
01.12.2020 | Commentary
Recommendations for the use of vascular access in the COVID-19 patients: an Italian perspective
Mauro Pittiruti, Fulvio Pinelli, Mauro Pittiruti, Fulvio Pinelli, Maria Giuseppina Annetta, Sergio Bertoglio, Daniele G. Biasucci, Roberto Biffi, Simona Biondi, Fabrizio Brescia, Massimo Buononato, Giuseppe Capozzoli, Paolo Cotogni, Elisa Deganello, Laura Dolcetti, Daniele Elisei, Stefano Elli, Davide Giustivi, Emanuele Iacobone, Antonio La Greca, Massimo Lamperti, Giada Maspero, Giancarlo Scoppettuolo, Davide Vailati, Daniele Vezzali
Open Access
01.12.2020 | Research
Urine cell cycle arrest biomarkers distinguish poorly between transient and persistent AKI in early septic shock: a prospective, multicenter study
Dimitri Titeca-Beauport, Delphine Daubin, Ly Van Vong, Guillaume Belliard, Cédric Bruel, Sami Alaya, Karim Chaoui, Maud Andrieu, Isabelle Rouquette-Vincenti, Frederic Godde, Michel Pascal, Momar Diouf, Christophe Vinsonneau, Kada Klouche, Julien Maizel
Open Access
01.12.2020 | Research
Duration of antibiotic therapy in critically ill patients: a randomized controlled trial of a clinical and C-reactive protein-based protocol versus an evidence-based best practice strategy without biomarkers
Isabela Borges, Rafael Carneiro, Rafael Bergo, Larissa Martins, Enrico Colosimo, Carolina Oliveira, Saulo Saturnino, Marcus Vinícius Andrade, Cecilia Ravetti, Vandack Nobre, Isabela N. Borges, Rafael M. Carneiro, Rafael Bergo, Larissa N. Martins, Enrico A. Colosimo, Carolina F. Oliveira, Saulo F. Saturnino, Marcus Vinícius M. Andrade, Cecilia G. Ravetti, Vandack Nobre
Open Access
01.12.2020 | Research
Hypertonic sodium lactate improves microcirculation, cardiac function, and inflammation in a rat model of sepsis
Emmanuel Besnier, David Coquerel, Geoffrey Kouadri, Thomas Clavier, Raphael Favory, Thibault Duburcq, Olivier Lesur, Soumeya Bekri, Vincent Richard, Paul Mulder, Fabienne Tamion
Open Access
22.06.2020 | COVID-19 | Review
Prevention of thrombotic risk in hospitalized patients with COVID-19 and hemostasis monitoring
Sophie Susen, Charles Ambroise Tacquard, Alexandre Godon, Alexandre Mansour, Delphine Garrigue, Philippe Nguyen, Anne Godier, Sophie Testa, Jerrold H. Levy, Pierre Albaladejo, Yves Gruel, P. Albaladejo, N. Blais, F. Bonhomme, A. Borel-Derlon, A. Cohen, J.-P. Collet, E. de Maistre, P. Fontana, D. Garrigue Huet, A. Godier, Y. Gruel, A. Godon, B. Ickx, S. Laporte, D. Lasne, J. Llau, G. Le Gal, T. Lecompte, S. Lessire, J. H. Levy, D. Longrois, S. Madi-Jebara, A. Mansour, M. Mazighi, P. Mismetti, P. E. Morange, S. Motte, F. Mullier, N. Nathan, P. Nguyen, G. Pernod, N. Rosencher, S. Roullet, P. M. Roy, S. Schlumberger, P. Sié, A. Steib, S. Susen, C. A. Tacquard, S. Testa, A. Vincentelli, P. Zufferey, A. Borel-Derlon, E. Boissier, B. Dumont, E. de Maistre, Y. Gruel, C. James, D. Lasne, T. Lecompte, P. E. Morange, P. Nguyen, V. Siguret, S. Susen
Open Access
01.12.2020 | Research
Mobilization practices in critically ill children: a European point prevalence study (EU PARK-PICU)
Erwin Ista, Barnaby R. Scholefield, Joseph C. Manning, Irene Harth, Orsola Gawronski, Alicja Bartkowska-Śniatkowska, Anne-Sylvie Ramelet, Sapna R. Kudchadkar, Paul C. Ritson, Filippia Nikolaou, Marjorie de Neef, Martin Kneyber, Kate Penny-Thomas, Christina Linton, Reinis Balmaks, Matthias Richter, Fabrizio Chiusolo, Corrado Cecchetti, Marco Roberti, Michela Di Furia, Chantal Grandjean, Bettina Nygaard, Yolanda Lopez, Tolga Koroglu, Tolga Besci, Roberta Da Rin Della Mora, Rachel S. Agbeko, Emma Borrows, Nathalie Bochaton, Janet Mattsson, Anne Ksellmann, Barbara Hero, Jowita Rosada-Kurasinska, Magdalena Świder, Amabile Bonaldi, Cristina Giugni, Siva Oruganti, Simon Gates, Hazel Smith, Annelies van Zwol, Jenna Hills, Johanna Conroy, Mark Bebbington, Felix Neunhoeffer, Els Duval
Open Access
01.12.2020 | Review
Update of the treatment of nosocomial pneumonia in the ICU
Rafael Zaragoza, Pablo Vidal-Cortés, Gerardo Aguilar, Marcio Borges, Emili Diaz, Ricard Ferrer, Emilio Maseda, Mercedes Nieto, Francisco Xavier Nuvials, Paula Ramirez, Alejandro Rodriguez, Cruz Soriano, Javier Veganzones, Ignacio Martín-Loeches
Open Access
01.12.2020 | Research
Significance of body temperature in elderly patients with sepsis
Takashi Shimazui, Taka-aki Nakada, Keith R. Walley, Taku Oshima, Toshikazu Abe, Hiroshi Ogura, Atsushi Shiraishi, Shigeki Kushimoto, Daizoh Saitoh, Seitaro Fujishima, Toshihiko Mayumi, Yasukazu Shiino, Takehiko Tarui, Toru Hifumi, Yasuhiro Otomo, Kohji Okamoto, Yutaka Umemura, Joji Kotani, Yuichiro Sakamoto, Junichi Sasaki, Shin-ichiro Shiraishi, Kiyotsugu Takuma, Ryosuke Tsuruta, Akiyoshi Hagiwara, Kazuma Yamakawa, Tomohiko Masuno, Naoshi Takeyama, Norio Yamashita, Hiroto Ikeda, Masashi Ueyama, Satoshi Fujimi, Satoshi Gando, Takashi Shimazui, Taka-aki Nakada, Keith R. Walley, Taku Oshima, Toshikazu Abe, Hiroshi Ogura, Atsushi Shiraishi, Shigeki Kushimoto, Daizoh Saitoh, Seitaro Fujishima, Toshihiko Mayumi, Yasukazu Shiino, Takehiko Tarui, Toru Hifumi, Yasuhiro Otomo, Kohji Okamoto, Yutaka Umemura, Joji Kotani, Yuichiro Sakamoto, Junichi Sasaki, Shin-ichiro Shiraishi, Kiyotsugu Takuma, Ryosuke Tsuruta, Akiyoshi Hagiwara, Kazuma Yamakawa, Tomohiko Masuno, Naoshi Takeyama, Norio Yamashita, Hiroto Ikeda, Masashi Ueyama, Satoshi Fujimi, Satoshi Gando, Osamu Tasaki, Yasumitsu Mizobata, Hiraku Funakoshi, Toshiro Okuyama, Iwao Yamashita, Toshio Kanai, Yasuo Yamada, Mayuki Aibiki, Keiji Sato, Susumu Yamashita, Kenichi Yoshida, Shunji Kasaoka, Akihide Kon, Hiroshi Rinka, Hiroshi Kato, Hiroshi Okudera, Eichi Narimatsu, Toshifumi Fujiwara, Manabu Sugita, Yasuo Shichinohe, Hajime Nakae, Ryouji Iiduka, Mitsunobu Nakamura, Yuji Murata, Yoshitake Sato, Hiroyasu Ishikura, Yasuhiro Myojo, Yasuyuki Tsujita, Kosaku Kinoshita, Hiroyuki Yamaguchi, Toshihiro Sakurai, Satoru Miyatake, Takao Saotome, Susumu Yasuda, Toshikazu Abe, Hiroshi Ogura, Yutaka Umemura, Atsushi Shiraishi, Shigeki Kushimoto, Daizoh Saitoh, Seitaro Fujishima, Junichi Sasaki, Toshihiko Mayumi, Yasukazu Shiino, Taka-aki Nakada, Takehiko Tarui, Toru Hifumi, Yasuhiro Otomo, Joji Kotani, Yuichiro Sakamoto, Shin-ichiro Shiraishi, Kiyotsugu Takuma, Ryosuke Tsuruta, Akiyoshi Hagiwara, Kazuma Yamakawa, Naoshi Takeyama, Norio Yamashita, Hiroto Ikeda, Yasuaki Mizushima, Satoshi Gando
Open Access
06.07.2020 | COVID-19 | Research Letter
Nafamostat mesylate treatment in combination with favipiravir for patients critically ill with Covid-19: a case series
Kent Doi, Mahoko Ikeda, Naoki Hayase, Kyoji Moriya, Naoto Morimura, Hiromu Maehara, Shunsuke Tagami, Kazutaka Fukushima, Naho Misawa, Yutaro Inoue, Hitomi Nakamura, Daisuke Takai, Mio Kurimoto, Kurato Tokunaga, Miyuki Yamamoto, Ichiro Hirayama, Ryohei Horie, Yuri Endo, Kengo Hiwatashi, Mio Shikama, Daisuke Jubishi, Yoshiaki Kanno, Koh Okamoto, Sohei Harada, Shu Okugawa, Kohei Miyazono, Yasuyuki Seto, Jun-ichiro Inoue
Open Access
01.12.2020 | Review
Recommendations for core critical care ultrasound competencies as a part of specialist training in multidisciplinary intensive care: a framework proposed by the European Society of Intensive Care Medicine (ESICM)
Adrian Wong, Laura Galarza, Lui Forni, Daniel De Backer, Michael Slama, Bernard Cholley, Paul Mayo, Anthony McLean, Antoine Vieillard-Baron, Daniel Lichtenstein, Giovanni Volpicelli, Robert Arntfield, Ignacio Martin-Loeches, Gizella Melania Istrate, František Duška, Adrian Wong, Laura Galarza, Lui Forni, Daniel De Backer, Michael Slama, Bernard Cholley, Paul Mayo, Anthony McLean, Antoine Vieillard-Baron, Daniel Lichtenstein, Giovanni Volpicelli, Robert Arntfield, Ignacio Martin-Loeches, Gizella Melania Istrate, František Duška
Open Access
07.07.2020 | COVID-19 | Research
Clinical course and predictors of 60-day mortality in 239 critically ill patients with COVID-19: a multicenter retrospective study from Wuhan, China
Jiqian Xu, Xiaobo Yang, Luyu Yang, Xiaojing Zou, Yaxin Wang, Yongran Wu, Ting Zhou, Yin Yuan, Hong Qi, Shouzhi Fu, Hong Liu, Jia’an Xia, Zhengqin Xu, Yuan Yu, Ruiting Li, Yaqi Ouyang, Rui Wang, Lehao Ren, Yingying Hu, Dan Xu, Xin Zhao, Shiying Yuan, Dingyu Zhang, You Shang
Open Access
01.12.2020 | Research
Prone positioning in severe ARDS requiring extracorporeal membrane oxygenation
Jonathan Rilinger, Viviane Zotzmann, Xavier Bemtgen, Carin Schumacher, Paul M. Biever, Daniel Duerschmied, Klaus Kaier, Peter Stachon, Constantin von zur Mühlen, Manfred Zehender, Christoph Bode, Dawid L. Staudacher, Tobias Wengenmayer
Open Access
01.12.2020 | Research
The effect of short-course antibiotics on the resistance profile of colonizing gut bacteria in the ICU: a prospective cohort study
Christian Munck, Ravi U. Sheth, Edward Cuaresma, Jessica Weidler, Stephania L. Stump, Philip Zachariah, David H. Chong, Anne-Catrin Uhlemann, Julian A. Abrams, Harris H. Wang, Daniel E. Freedberg
Open Access
01.12.2020 | Research
Comparison of hydroxychloroquine, lopinavir/ritonavir, and standard of care in critically ill patients with SARS-CoV-2 pneumonia: an opportunistic retrospective analysis
Marie Lecronier, Alexandra Beurton, Sonia Burrel, Luc Haudebourg, Robin Deleris, Julien Le Marec, Sara Virolle, Safaa Nemlaghi, Côme Bureau, Pierre Mora, Martin De Sarcus, Olivier Clovet, Baptiste Duceau, Paul Henri Grisot, Marie Hélène Pari, Jérémy Arzoine, Ulrich Clarac, David Boutolleau, Mathieu Raux, Julie Delemazure, Morgane Faure, Maxens Decavele, Elise Morawiec, Julien Mayaux, Alexandre Demoule, Martin Dres
Open Access
14.07.2020 | COVID-19 | Review
Role of angiotensin-converting enzyme 2 (ACE2) in COVID-19
Wentao Ni, Xiuwen Yang, Deqing Yang, Jing Bao, Ran Li, Yongjiu Xiao, Chang Hou, Haibin Wang, Jie Liu, Donghong Yang, Yu Xu, Zhaolong Cao, Zhancheng Gao
Open Access
01.12.2020 | Research
The circular RNA landscape in specific peripheral blood mononuclear cells of critically ill patients with sepsis
Hina N. Khan, Xanthe Brands, Simona Aufiero, Arie J. Hoogendijk, Augustijn M. Klarenbeek, Tjitske S. R. van Engelen, Bastiaan W. Haak, Lonneke A. van Vught, Janneke Horn, Marcus J. Schultz, Aeilko H. Zwinderman, Tom van der Poll, Brendon P. Scicluna
Open Access
15.07.2020 | COVID-19 | Research Letter
Prone positioning under VV-ECMO in SARS-CoV-2-induced acute respiratory distress syndrome
Bruno Garcia, Nicolas Cousin, Claire Bourel, Mercé Jourdain, Julien Poissy, Thibault Duburcq, Pauline Boddaert, Arthur Durand, Ahmed El Kalioubie, Patrick Girardie, Marion Houard, Geoffrey Ledoux, Anne Sophie Moreau, Christopher Niles, Saad Nseir, Thierry Onimus, Aurelia Toussaint, Sebastien Préau, Laurent Robriquet, Anahita Rouze, Arthur Simonnet, Sophie Six, Morgan Caplan, Julien Goutay, Emmanuelle Jaillette, Erika Parmentier-Decrucq, Raphael Favory, Daniel Mathieu, Guillaume Degouy, Mouhamed Moussa
Open Access
01.12.2020 | Research
Multicenter evaluation of a syndromic rapid multiplex PCR test for early adaptation of antimicrobial therapy in adult patients with pneumonia
Céline Monard, Jonathan Pehlivan, Gabriel Auger, Sophie Alviset, Alexy Tran Dinh, Paul Duquaire, Nabil Gastli, Camille d’Humières, Adel Maamar, André Boibieux, Marion Baldeyrou, Julien Loubinoux, Olivier Dauwalder, Vincent Cattoir, Laurence Armand-Lefèvre, Solen Kernéis, Agathe Becker, Julien Charpentier, Julien Textoris, Claude-Alexandre Gustave, Grégory Destras, François Vandenesch, Bruno Lina, Jean Sebastien Casalegno, Manon Lejeune, Philippe Montravers, Claire Poyart, Hugo Tête, Jean-François Timsit, Thomas Uberti
Open Access
20.07.2020 | COVID-19 | Research
Development and validation of a risk factor-based system to predict short-term survival in adult hospitalized patients with COVID-19: a multicenter, retrospective, cohort study
Shuai Zhang, Mengfei Guo, Limin Duan, Feng Wu, Guorong Hu, Zhihui Wang, Qi Huang, Tingting Liao, Juanjuan Xu, Yanling Ma, Zhilei Lv, Wenjing Xiao, Zilin Zhao, Xueyun Tan, Daquan Meng, Shujing Zhang, E Zhou, Zhengrong Yin, Wei Geng, Xuan Wang, Jianchu Zhang, Jianguo Chen, Yu Zhang, Yang Jin
Open Access
01.12.2020 | Research
The effect of dexmedetomidine on vasopressor requirements in patients with septic shock: a subgroup analysis of the Sedation Practice in Intensive Care Evaluation [SPICE III] Trial
Luca Cioccari, Nora Luethi, Michael Bailey, Yahya Shehabi, Belinda Howe, Anna S. Messmer, Helena K. Proimos, Leah Peck, Helen Young, Glenn M. Eastwood, Tobias M. Merz, Jukka Takala, Stephan M. Jakob, Rinaldo Bellomo, Yahya Shehabi, Yaseen Arabi, Frances Bass, Rinaldo Bellomo, Simon Erickson, Belinda Howe, Suhaini Kadiman, Colin McArthur, Lynnette Murray, Michael Reade, Ian Seppelt, Jukka Takala, Steve A. Webb, Matthew P. Wise, Yahya Shehabi, Belinda Howe, Rinaldo Bellomo, Yaseen M. Arabi, Michael J. Bailey, Frances Bass, Suhaini Kadiman, Colin McArthur, Lynnette Murray, Michael Reade, Ian Seppelt, Jukka Takala, Steve A. Webb, Matthew P. Wise, Michael J. Bailey, Belinda D. Howe, Lynette Murray, Vanessa Singh
Open Access
20.07.2020 | COVID-19 | Research Letter
Neuromuscular blocking agents (NMBA) for COVID-19 acute respiratory distress syndrome: a multicenter observational study
Romain Courcelle, Stéphane Gaudry, Nicolas Serck, Gauthier Blonz, Jean-Baptiste Lascarrou, David Grimaldi, Nadia Aissaoui, Giuseppe Carbutti, Alain D’hondt, Julien Higny, Geoffrey Horlait, Sami Hraiech, Laurent Lefebvre, Francois Lejeune, Andre Ly, Michael Piagnerelli, Bertrand Sauneuf, Thibaud Soumagne, Piotr Szychowiak, Julien Textoris, Benoit Vandenbunder, Christophe Vinsonneau
Open Access
01.12.2020 | Research
Automated vs. conventional ventilation in the ICU: a randomized controlled crossover trial comparing blood oxygen saturation during daily nursing procedures (I-NURSING)
Jonathan Chelly, Sandie Mazerand, Sebastien Jochmans, Claire-Marie Weyer, Franck Pourcine, Olivier Ellrodt, Nathalie Thieulot-Rolin, Jean Serbource-Goguel, Oumar Sy, Ly Van Phach Vong, Mehran Monchi
Open Access
23.07.2020 | COVID-19 | Review
Nebulised heparin as a treatment for COVID-19: scientific rationale and a call for randomised evidence
Frank M. P. van Haren, Clive Page, John G. Laffey, Antonio Artigas, Marta Camprubi-Rimblas, Quentin Nunes, Roger Smith, Janis Shute, Mary Carroll, Julia Tree, Miles Carroll, Dave Singh, Tom Wilkinson, Barry Dixon
Open Access
29.07.2020 | COVID-19 | Research
Cardiac injury associated with severe disease or ICU admission and death in hospitalized patients with COVID-19: a meta-analysis and systematic review
Xinye Li, Xiandu Pan, Yanda Li, Na An, Yanfen Xing, Fan Yang, Li Tian, Jiahao Sun, Yonghong Gao, Hongcai Shang, Yanwei Xing
Open Access
01.12.2020 | Research
Artificial neural networks improve early outcome prediction and risk classification in out-of-hospital cardiac arrest patients admitted to intensive care
Jesper Johnsson, Ola Björnsson, Peder Andersson, Andreas Jakobsson, Tobias Cronberg, Gisela Lilja, Hans Friberg, Christian Hassager, Jesper Kjaergard, Matt Wise, Niklas Nielsen, Attila Frigyesi
Open Access
01.12.2020 | Correction
Correction to: Urine cell cycle arrest biomarkers distinguish poorly between transient and persistent AKI in early septic shock: a prospective, multicenter study
Dimitri Titeca-Beauport, Delphine Daubin, Ly Van Vong, Guillaume Belliard, Cédric Bruel, Sami Alaya, Karim Chaoui, Maud Andrieu, Isabelle Rouquette-Vincenti, Frederic Godde, Michel Pascal, Momar Diouf, Christophe Vinsonneau, Kada Klouche, Julien Maizel
Open Access
06.08.2020 | SARS-CoV-2 | Research
International variation in the management of severe COVID-19 patients
Elie Azoulay, Jan de Waele, Ricard Ferrer, Thomas Staudinger, Marta Borkowska, Pedro Povoa, Katerina Iliopoulou, Antonio Artigas, Stefan J. Schaller, Manu Shankar-Hari, Mariangela Pellegrini, Michael Darmon, Jozef Kesecioglu, Maurizio Cecconi
Open Access
01.12.2020 | Research
High-flow nasal cannula oxygen therapy versus non-invasive ventilation for chronic obstructive pulmonary disease patients after extubation: a multicenter, randomized controlled trial
Dingyu Tan, Joseph Harold Walline, Bingyu Ling, Yan Xu, Jiayan Sun, Bingxia Wang, Xueqin Shan, Yunyun Wang, Peng Cao, Qingcheng Zhu, Ping Geng, Jun Xu
Open Access
01.12.2020 | Research
ECCO2R therapy in the ICU: consensus of a European round table meeting
Alain Combes, Georg Auzinger, Gilles Capellier, Damien du Cheyron, Ian Clement, Guglielmo Consales, Wojciech Dabrowski, David De Bels, Francisco Javier González de Molina Ortiz, Antje Gottschalk, Matthias P. Hilty, David Pestaña, Eduardo Sousa, Redmond Tully, Jacques Goldstein, Kai Harenski
Open Access
09.08.2020 | COVID-19 | Research
Delirium and encephalopathy in severe COVID-19: a cohort analysis of ICU patients
Julie Helms, Stéphane Kremer, Hamid Merdji, Malika Schenck, François Severac, Raphaël Clere-Jehl, Antoine Studer, Mirjana Radosavljevic, Christine Kummerlen, Alexandra Monnier, Clotilde Boulay, Samira Fafi-Kremer, Vincent Castelain, Mickaël Ohana, Mathieu Anheim, Francis Schneider, Ferhat Meziani
Open Access
10.08.2020 | COVID-19 | Research Letter
Therapeutic plasma exchange in patients with COVID-19 pneumonia in intensive care unit: a retrospective study
Bulent Gucyetmez, Hakan Korkut Atalan, Ibrahim Sertdemir, Ulkem Cakir, Lutfi Telci, Aylin Ogan, Aylin Cimet Ayyildiz, Berrin Yalcin, Behiye Oren, Fadıl Havas, Sevda Dizi, Birsen Kose, Umran Yakici, Cenk Sahan, Elif Ozkilitci, Ugur Tunali, Deniz Gunes, Ozlem Dincer, Reyhan Sahin, Duran Ozdemir, Mehtap Selcuk, Ceyhun Solakoglu, Unsal Arif Turan, Erkan Kaya, Mustafa Emre Kavlak, Pelin Katar, Hande Aygun, Kerim Cikim, Ozkan Uysal, Nur Ozturk Kaskir, Aysun Soylu
Open Access
13.08.2020 | COVID-19 | Research
Unspecific post-mortem findings despite multiorgan viral spread in COVID-19 patients
Myriam Remmelink, Ricardo De Mendonça, Nicky D’Haene, Sarah De Clercq, Camille Verocq, Laetitia Lebrun, Philomène Lavis, Marie-Lucie Racu, Anne-Laure Trépant, Calliope Maris, Sandrine Rorive, Jean-Christophe Goffard, Olivier De Witte, Lorenzo Peluso, Jean-Louis Vincent, Christine Decaestecker, Fabio Silvio Taccone, Isabelle Salmon
Open Access
01.12.2020 | Review
Biomarkers in critical care nutrition
Christian Stoppe, Sebastian Wendt, Nilesh M. Mehta, Charlene Compher, Jean-Charles Preiser, Daren K. Heyland, Arnold S. Kristof
Open Access
19.08.2020 | COVID-19 | Research Letter
Usefulness and safety of a dedicated team to prone patients with severe ARDS due to COVID-19
Antoine Kimmoun, Bruno Levy, Bruno Chenuel, S. Barde, A. Didelot, B. Chenuel, P. Zieminski, M. Lorcin, C. Schweitzer, R. Karunna, V. Moulin, M. Huet, F. Lacour, P. Rodriguez, D. Grandmougin, Y. Liu, P. A. Metzdorf, M. Costa, T. Fouquet, A. Germain, H. Chanty, J. Levy, A. Didier, J. Lawton, C. Parietti-Winkler, A. Manuguerra, C. Mazeaud, C. Gaulier, C. Rumeau, L. Bourson, M. Cholley-Roulleau, A. Ionescu, A. Gatin, M. Perez, A. Schwanké, G. Lauria, L. Freysz, T. Cuinet, J. Chauvelot, C. Mottola, T. Toussaint, L. Dechambenoit, F. Lagrange, C. Mathieu, C. Clément, H. Benamron, L. Dubouis, H. Kremer, L. Cabanel, M. Falcetta, V. Gorzkowski, P. Campoli, J. Cavailhes, J. Zavoli, C. Nominé-Criqui, J. Felloni, V. Cloché-Fouquet, F. G. Midon, G. Vaz, D. Valentin, V. Perkovic, A. Courandon, Y. Briot, A. Epin, K. Dreller, L. Florion, C. Larose, M. Barron, C. Sadoul, M. Gimbert, M. Fernandez, T. Thomas, P. Bichet, N. Petkunaite, S. Brahami, D. Nguyen, G. Vaz, A. Schaefer, C. Fabbri, C. Ferri, A. Gegout, A. Poncy, R. Delaplace, M. Ammisaid, J. Rebois, B. Vendeville, C. Dubroux, R. Raynaud, S. Moog, C. Cottez, L. Woirhaye, J. Menet, A. C. Madkaud, L. Naisseline, C. Mathieu, T. Raze, F. Violon, M. Meiers, D. Albanesi, O. Durand, L. Textoris, T. Dubost
Open Access
01.12.2020 | Research
Incidence and outcomes of acute respiratory distress syndrome in intensive care units of mainland China: a multicentre prospective longitudinal study
Xu Huang, Ruoyang Zhang, Guohui Fan, Dawei Wu, Haining Lu, Daoxin Wang, Wang Deng, Tongwen Sun, Lihua Xing, Shaohua Liu, Shilei Wang, Ying Cai, Ye Tian, Yi Zhang, Jingen Xia, Qingyuan Zhan, Lixin Xie, Ying Wang, Li Weng, Guangfa Zhu, Yan Liu, Man Song, Yanming Zhao, Jing Chen, Hongwen Zhao, Haijia Hou, Jingping Yang, Rina Wu, Xiyuan Xu, Xixin Yan, Haibo Xu, Dawei Wu, Haining Lu, Gengyun Sun, Dan Zhang, Beilei Zhao, Binhai Pan, Jialin Liu, Ruoming Tan, Pinhua Pan, Rongli Lu, Hong Luo, Han Zhang, Daoxin Wang, Wang Deng, Yusheng Chen, Fengfeng Lu, Sicheng Xu, Xia Luo, Hong Teng, Lijuan Chen, Lihua Xing, Shilei Wang, Tongwen Sun, Shaohua Liu, Bing Han, Yunlu Li
Open Access
01.12.2020 | Research
Assessing physicians’ and nurses’ experience of dying and death in the ICU: development of the CAESAR-P and the CAESAR-N instruments
Florence Boissier, Valérie Seegers, Amélie Seguin, Stéphane Legriel, Alain Cariou, Samir Jaber, Jean-Yves Lefrant, Thomas Rimmelé, Anne Renault, Isabelle Vinatier, Armelle Mathonnet, Danielle Reuter, Olivier Guisset, Christophe Cracco, Jacques Durand-Gasselin, Béatrice Éon, Marina Thirion, Jean-Philippe Rigaud, Bénédicte Philippon-Jouve, Laurent Argaud, Renaud Chouquer, Laurent Papazian, Céline Dedrie, Hugues Georges, Eddy Lebas, Nathalie Rolin, Pierre-Edouard Bollaert, Lucien Lecuyer, Gérald Viquesnel, Marc Leone, Ludivine Chalumeau-Lemoine, Maité Garrouste-Orgeas, Elie Azoulay, Nancy Kentish-Barnes
Open Access
28.08.2020 | COVID-19 | Research
Longitudinal changes of inflammatory parameters and their correlation with disease severity and outcomes in patients with COVID-19 from Wuhan, China
Zhilin Zeng, Haijing Yu, Huilong Chen, Weipeng Qi, Liang Chen, Guang Chen, Weiming Yan, Tao Chen, Qin Ning, Meifang Han, Di Wu
Open Access
31.08.2020 | COVID-19 | Research
Respiratory physiology of COVID-19-induced respiratory failure compared to ARDS of other etiologies
Domenico Luca Grieco, Filippo Bongiovanni, Lu Chen, Luca S. Menga, Salvatore Lucio Cutuli, Gabriele Pintaudi, Simone Carelli, Teresa Michi, Flava Torrini, Gianmarco Lombardi, Gian Marco Anzellotti, Gennaro De Pascale, Andrea Urbani, Maria Grazia Bocci, Eloisa S. Tanzarella, Giuseppe Bello, Antonio M. Dell’Anna, Salvatore M. Maggiore, Laurent Brochard, Massimo Antonelli
Open Access
01.12.2020 | Research
Body-mass index and long-term risk of sepsis-related mortality: a population-based cohort study of 0.5 million Chinese adults
Li Weng, Junning Fan, Canqing Yu, Yu Guo, Zheng Bian, Yuxia Wei, Ling Yang, Yiping Chen, Huaidong Du, Liang Chang, Weiwei Gong, Junshi Chen, Zhengming Chen, Bin Du, Jun Lv, Liming Li
Open Access
01.12.2020 | Review
The importance of airway and lung microbiome in the critically ill
Ignacio Martin-Loeches, Robert Dickson, Antoni Torres, Håkan Hanberger, Jeffrey Lipman, Massimo Antonelli, Gennaro de Pascale, Fernando Bozza, Jean Louis Vincent, Srinivas Murthy, Michael Bauer, John Marshall, Catia Cilloniz, Lieuwe D. Bos
Open Access
01.12.2020 | Research
Hydrocortisone treatment is associated with a longer duration of MODS in pediatric patients with severe sepsis and immunoparalysis
Katherine E. Bline, Melissa Moore-Clingenpeel, Josey Hensley, Lisa Steele, Kristin Greathouse, Larissa Anglim, Lisa Hanson-Huber, Jyotsna Nateri, Jennifer A. Muszynski, Octavio Ramilo, Mark W. Hall
Open Access
01.12.2020 | Research
(1,3)-β-d-Glucan-based empirical antifungal interruption in suspected invasive candidiasis: a randomized trial
Gennaro De Pascale, Brunella Posteraro, Sonia D’Arrigo, Giorgia Spinazzola, Rita Gaspari, Giuseppe Bello, Luca Maria Montini, Salvatore Lucio Cutuli, Domenico Luca Grieco, Valentina Di Gravio, Giulia De Angelis, Riccardo Torelli, Elena De Carolis, Mario Tumbarello, Maurizio Sanguinetti, Massimo Antonelli
Open Access
01.12.2020 | Research
Cross-sectional study for the clinical application of extracorporeal membrane oxygenation in Mainland China, 2018
Wei Cheng, Xu-Dong Ma, Long-Xiang Su, Huai-Wu He, Lu Wang, Bo Tang, Wei Du, Yuan-kai Zhou, Hao Wang, Na Cui, Yun Long, Da-Wei Liu, Yan-Hong Guo, Ye Wang, Guang-Liang Shan, Xiang Zhou, Shu-Yang Zhang, Yu-Pei Zhao
Open Access
01.12.2020 | Research
Understanding the neuroprotective effect of tranexamic acid: an exploratory analysis of the CRASH-3 randomised trial
Amy Brenner, Antonio Belli, Rizwana Chaudhri, Timothy Coats, Lauren Frimley, Sabariah Faizah Jamaluddin, Rashid Jooma, Raoul Mansukhani, Peter Sandercock, Haleema Shakur-Still, Temitayo Shokunbi, Ian Roberts, Ian Roberts, Haleema Shakur-Still, Amy Aeron-Thomas, Antonio Belli, Amy Brenner, Muhammad Anwar Chaudary, Rizwana Chaudhri, Sabariah Faizah Bt Jamaluddin, Lauren Frimley, Kiran Javaid, Rashid Jooma, Aasia Kayani, Caroline Leech, Khalid Mahmood, Raoul Mansukhani, Julina Md Noor, Jorge Mejia-Mantilla, Phil Moss, Jason Pott, Peter Sandercock, Temitayo Shokunbi, Liliana Vallecilla, Henry Benjamin Hartzenberg, Manjul Joshipura, Pablo Perel, Michael J. Clarke, Samuel C. Ohaegbulam, Anthony Rodgers, Tony Brady, Yashbir Dewan, Phil Edwards, Edward O. Komolafe, Monica Arribas, Emma Austin, Eni Balogun, Lin Barneston, Collette Barrow, Danielle Beaumont, Myriam Benyahia, Imogen Brooks, Madeleine Cargill, Laura Carrington, Lisa Cook, Beatrice Cornu-Hewitt, Amber Geer, Daniel Gilbert, Catherine Gilliam, Julio Gil-Onandia, Daniel Hetherington, Courtenay Howe, Carolyn Hughes, David I’anson, Rob Jackson, Miland Joshi, Sneha Kansagra, Taemi Kawahara, Katharine Ker, Sergey Kostrov, Abda Mahmood, Hakim Miah, Bernard Ndungu, Kelly Needham, Cecilia Okusi, Aroudra Outtandy, Raul Pardinaz-Solis, Daniel Pearson, Tracey Pepple, Claude Pisani, David Prieto-Merino, Danielle Prowse, Nigel Quashi, Anna Quinn, Maria Ramos, Mia Reid, Chris Roukas, Giulia Scrapa, Chelci Squires, Jemma Tanner, Andrew Thayne, Lesley Vidaurre, Elizabeth Woods, Bukola Fawole, Olusade Adetayo, Olujide Okunade, Tamar Gogichaishvili, Maria de los Angeles Munoz-Sanchez, Fatos Olldashi, Satish Krishnan, Vincent Djientcheu, Jorge Loria Castellanos, Frank Rasulo, Qadamkhear Hama, Yakub Mulla, Ioan Stefan Florian, Juan Tobar, Hussein Khamis, Conor Deasy, Bobby Wellsh, Jean Williams-Johnson, Susilo Chandra, Vincent Mutiso, Rizwan Butt, Muhammad Hammad Nasir, Salman Ahmad, Farwah Aslam, Khurram Ishaque, Faheem Usmani, Shahrukh Rizvi, Farhad Ali, Omair Sajjad, Ali Zunair, Lal Rehman, Raza Rizvi, Farrukh Javeed, Shakeel Ahmed, Asad Abbas, Ali Afzal, Ali Mikdad, Asif Bashir, Anwar Chaudary, Tariq Salahuddin, Bashir Ahemed, Amir Aziz, Naveed Ashraf, Shahzad Hussain, Usman Ahmad, Muhammad Asif, Muhammad Adil, Adeel Rauf, Rizwan Khan, Bilal Ahmad, Umair Afzal, Hassan Raza, Quratul Ain, Sajjad Yaqoob, Qaiser Waseem, Muffasser Nishat, Suneel Semvel, Javed Iqbal, Samra Majeed, Sana Zulfiqar, Madeeha Iqbal, Nazia Majeed, Manzoor Ahmed, Nadeem Akhtar, Mohammad Malik, Yasir Shehzad, Muhammad Yousaf, Abdul Wahid, Abdul Samad, Saifullah Shah, Mumtaz Ali, Jehan Zeb, Abdus Salam Khan, Adeela Irfan, Salman Sharif, Riaz Memon, Ben Bloom, Tim Harris, Imogen Skene, Geoffrey Bellhouse, Olivia Boulton, Geraldine Ward, Catherine Jarvis, Carly Swann, Sathananathan Ratnam, Ronald Carrera, Kamal Yakoub, David Davies, Emma Fellows, Heather Jarman, Sarah Rounding, Elizabeth Johnson, Catherine Loughran, Fiona Lecky, Kate Clayton, Angiy Michael, Angela Coumbarides, Jason Kendall, Beverley Faulkner, Ruth Worner, Emma Gendall, Philip Hopkins, Paul Riozzi, Hannah Cotton, Raine Astin-Chamberlain, Mark Wilson, Jan Bodnar, Rachel Williams, Alberto Rigoni, Abdo Sattout, John Fletcher, Calum Edge, Nina Maryanji, Adrian Boyle, Susie Hardwick, Ellen Nichols, Catherine Hayhurst, Frank Coffey, Chris Gough, Philip Miller, Lucy Ryan, Melanie Darwent, Alexis Espinosa, Sally Beer, Julie Norton, Holly Maguire, Kay Finney, Anthony Kehoe, Rosalyn Squire, Alison Jeffery, Christiane Vorwerk, Denise Foord, Eliot Wilkinson, Avril Kuhrt, Shammi Ramlakhan, Stuart Reid, Andy Curran, Sean McMullan, Tajek Hassan, Stuart Nuttall, Stephen Haig, Saif Al-Nahhas, Diederik Bulters, Ardalan Zolnourian, Tamsin Ribbons, Ian Mew, Tanya de Weymarn, Victoria Hughes, Jane McVicar, Cieran McKiernan, Liza Keating, Henrik Reschreiter, Judith Wright, Louisa Chan, Himanshu Kataria, Alastair Ireland, Richard Body, Alasdair Corfield, Shindo Francis, William Townend, Timothy Coats, James Gagg, Sarah Wilson, Rowley Cottingham, Simon Tucker, Frank Sutherland, Louisa Mitchell, Lucy Parker, Ola Afolabi, Fiona Hunter, Mark Jadav, Kayode Adeboye, Mandy Grocutt, Gabrielle May, David Watson, Andrea Wootten, Sarah Robertshaw, Susan Dorrian, Rob Perry, Hyun Choi, Claire McGroarty, Paul Shone, David Maritz, Sabariah Jamaluddin, Julina Noor, Norizan Rosli, Leonard Leong Sang Xian, Yong De Jun, Fatahul Mohamed, Cheng Hee Song, Arman Hawari, Leong Yuen Chin, Hardawani Mohd Hussein, Mohd Lotfi, Hafiq Hamid, Nujaimin Udin, Peck Lian, See Choo, Kwanhathai Wong, Fathiyah Gani, Mardhiah Jusoh, Darrsini Rajakumar, Chia Boon Yang, Nur Shahidah Binti Dzulkiflee, Wong Chok Ky, Muhaimin Azwan Bin Mohd Azman, Adi Bin Osman, Azma Haryaty Ahmad, Ramzuzaman Ismail, Si Qi Lai, Mohd Amin Bin Mohidin, Norwani Binti Deraman, Salliza Binti Selamat, Ida Abidin, Nurkhairulnizam Halim, Zuraini Bakar, Zainalabidin Mohamed Ismail, Badrul Hisham, Ruhaida Kamal, Zainal Effendy, Mashitah Ismail, Noor Azleen, Liu Yeo Seng, Kamarul Aryffin Baharuddin, Regunath Kandasamy, Azlan Kamalludin, Shamsul Asmee, Mohd Fadzil, Ahmad Basitz, Norhaya Abdullah, Giorgi Ingorokva, Shota Ingorokva, Iamze Agdgomelashvili, Kote Mumladze, Ioseb Maisuradze, Iulia Kugusheva, Buba Shalamberidze, Gia Tomadze, Juan Fernandez-Ortega, Raimundo Seara-Valero, Guillermo Ibañez-Botella, Victoria Garcia-Martinez, Melida Garcia Martul, Santiago Freita Ramos, Guillermo Lago Preciado, Claudio Garcia-Alfaro, Angeles Munoz-Sanchez, Rafael Bellido-Alba, Carmen Corcobado, Ana Bueno, Alfonso Ambros, Juan Tihista Jimenez, Jose Roldan Ramirez, José Martín, Laura Inés Rodríguez, Jaime Fontanals, José Manuel Jiménez-Moragas, Joaquín Paya Berbegal, Olaomi Oluwole, Raji Mahmud, Nancy Ukwu, Femi Bankole, Abidemi Oseni, Bamidele Adebayo, Adefolarin Malomo, Liadi Tiamiyu, Adefisayo Adekanmbi, Lateef Thanni, Ayodeji Olubodun, Fidelis Ojeblenu, Michael Uwaezuoke, Edward Komolafe, Oluwafemi Owagbemi, Fatai Ishola, Adewumi Durodola, Ukpong Udoffa, Adeniran James, Azeez Tella, Andrew Dongo, Uchechi Ekpemiro, Stanley Anyanwu, Nafiu Aigoro, Wilfred Mezue, Danaan Shilong, Abiodun Azeez, Olakunle Babalola, Mohammed Ibrahim, Joseph Obande, Alfredo Constain Franco, Edwin Vasquez Salazar, Sebastian Betancur Londoño, Viviana Medina Cardona, Carlos Morales, Santiago Naranjo, July Agudelo, Sandra Carvajal, Yidhira Fajardo-Gaviria, Yam Roka, Ushma Ghising, Narayani Roka, Manzil Shrestha, Upendra Devkota, Bivek Vaidya, Pankaj Nepal, Amit Thapa, Bidur KC, Ajit Shrestha, Rajiv Jha, Prabin Shrestha, Irgen Hodaj, Erion Spaho, Asllan Selaj, Nirian Bendo, Tomohisa Shoko, Hideki Endo, Atsushi Senda, Yasushi Hagihara, Takashi Fuse, Naohisa Masunaga, Yasuhiro Otomo, Ryuichiro Egashira, Takahiro Ohnuki, Alya AlMazmi, Subrata Saha, Alexander Suvarov, Than Latt Aung, Kaung Myat Tun, Tint Tint Khaing, Thinzar Maw, Orlane Ndome, Mireille Moumi, André Mbida, Joseph Fondop, Mba Sebastien, Abdul Azim, Jan Adil, Zabiullah Amiry, Jorge Loría-Castellanos, Nancy Guevara Rubio, Patricia Ortega Leon, Francisco Estrada, Erandy Montes de Oca-García, Hafid Sanchez, Angélica Soria, Paola Bonucci, Federico Franchi, Alan Girardini, Himdad Hameed, Muhammad Basim, Simon Stock, Eap Hourt, Ali Ilunga, Jonathan Mulenga, Horia Ples, Adam Danil, Mircea Gorgan, Ioan Florian, Dusan Vlahovic, James French, Jeffrey East, Antonius Kurniawan, Julius Kiboi
Open Access
01.12.2020 | COVID-19 | Research
Thrombotic and haemorrhagic complications in critically ill patients with COVID-19: a multicentre observational study
Akshay Shah, Killian Donovan, Anna McHugh, Manish Pandey, Louise Aaron, Charlotte A. Bradbury, Simon J. Stanworth, Raza Alikhan, Stephen Von Kier, Keith Maher, Nicola Curry, Susan Shapiro, Matthew J. Rowland, Matt Thomas, Richard Mason, Matthew Holland, Tom Holmes, Michael Ware, Stefan Gurney, Stuart R. McKechnie
Open Access
01.12.2020 | Research
ICU admission body composition: skeletal muscle, bone, and fat effects on mortality and disability at hospital discharge—a prospective, cohort study
Ariel Jaitovich, Camille L. Dumas, Ria Itty, Hau C. Chieng, Malik M. H. S. Khan, Ali Naqvi, John Fantauzzi, Jesse B. Hall, Paul J. Feustel, Marc A. Judson
Open Access
01.12.2020 | Research
Cost-effectiveness of adrenaline for out-of-hospital cardiac arrest
Felix Achana, Stavros Petrou, Jason Madan, Kamran Khan, Chen Ji, Anower Hossain, Ranjit Lall, Anne-Marie Slowther, Charles D. Deakin, Tom Quinn, Jerry P. Nolan, Helen Pocock, Nigel Rees, Michael Smyth, Simon Gates, Dale Gardiner, Gavin D. Perkins, Stavros Petrou, Jason Madan, Kamran Khan, Chen Ji, Anower Hossain, Ranjit Lall, Anne-Marie Slowther, Charles D. Deakin, Tom Quinn, Jerry P. Nolan, Helen Pocock, Nigel Rees, Michael Smyth, Simon Gates, Dale Gardiner, Gavin D. Perkins, Matthew Cooke, Sarah Lamb, Andrew Carson, Ian Jacobs, Ed England, John Black, Nicola Brock, Claire Godfrey, Sarah Taylor, Michelle Thomson, Isabel Rodriguez-Bachiller, Claire King, Marie Stevens, Johanna Lazarus, Helen Werts, Joshua Golding, Rachel Fothergill, Fionna Moore, Alex Boda, Richard Whitfield, Laura Galligan, Rob Lovett, Jennifer Bradley, Lyndsay O’Shea, Mark Docherty, Imogen Gunsen, Gill Price, Andy Rosser, Garry Parcell, Mindy Jhamat, Josh Miller, Jenny Sears Brown, Alice Pretty, Madison Larden, Emma Harris, Jenny Lumley-Holmes, Rhiannon Boldy, Prudence Horwood, Kyee Han, Karl Charlton, Sonia Byers, Gary Shaw, Matt Limmer, Craig Wynne, Michelle Jackson, Emma Bell, Oliver Gupta, Rima Gupta, Charlotte Scomparin, Susie Hennings, Jessica Horton, James Buck, Sarah Rumble, Hayley Johnson, Eva Kritzer, Chockalingham Muthiah, Adrian Willis, Claire Daffern, Louise Clarkson, Felix Achana, Nicola Cashin, Emma Skilton, Malvenia Richmond, Martin Underwood, Natalie Strickland, Sarah Duggan, Scott Regan, Jill Wood, Jon Nicholl, Neil Bayliss, Helen Snooks, Jonathan Benger, Robert Andrews, David Pitcher, William Lee, Matt Wise, Marion Campbell, Jasmeet Soar, Kathy Rowan, Sue Mason
Open Access
01.12.2020 | COVID-19 | Research Letter
Persistent hypermetabolism and longitudinal energy expenditure in critically ill patients with COVID-19
John Whittle, Jeroen Molinger, David MacLeod, Krista Haines, Paul E. Wischmeyer, John Whittle, Jeroen Molinger, David MacLeod, Krista Haines, Paul E. Wischmeyer, Anthony Sung, Marat Fudim, Lindsie Boerger, Kathryn Lessig, Jessica Lumbard, Leslie C. Murray, Sue Steves, Jhana Parikh, Jacob Ribet, Melanie Hollidge
Open Access
01.12.2020 | Research
Epinephrine’s effects on cerebrovascular and systemic hemodynamics during cardiopulmonary resuscitation
Constantine D. Mavroudis, Tiffany S. Ko, Ryan W. Morgan, Lindsay E. Volk, William P. Landis, Benjamin Smood, Rui Xiao, Marco Hefti, Timothy W. Boorady, Alexandra Marquez, Michael Karlsson, Daniel J. Licht, Vinay M. Nadkarni, Robert A. Berg, Robert M. Sutton, Todd J. Kilbaugh
Open Access
01.12.2020 | COVID-19 | Research
Efficacy of tocilizumab in patients with COVID-19 ARDS undergoing noninvasive ventilation
Francesco Menzella, Matteo Fontana, Carlo Salvarani, Marco Massari, Patrizia Ruggiero, Chiara Scelfo, Chiara Barbieri, Claudia Castagnetti, Chiara Catellani, Giorgia Gibellini, Francesco Falco, Giulia Ghidoni, Francesco Livrieri, Gloria Montanari, Eleonora Casalini, Roberto Piro, Pamela Mancuso, Luca Ghidorsi, Nicola Facciolongo
Open Access
01.12.2020 | COVID-19 | Research
Awake prone positioning does not reduce the risk of intubation in COVID-19 treated with high-flow nasal oxygen therapy: a multicenter, adjusted cohort study
Carlos Ferrando, Ricard Mellado-Artigas, Alfredo Gea, Egoitz Arruti, César Aldecoa, Ramón Adalia, Fernando Ramasco, Pablo Monedero, Emilio Maseda, Gonzalo Tamayo, María L. Hernández-Sanz, Jordi Mercadal, Ascensión Martín-Grande, Robert M. Kacmarek, Jesús Villar, Fernando Suárez-Sipmann, Marina Vendrell, Gerard Sánchez-Etayo, Amalia Alcón, Isabel Belda, Mercé Agustí, Albert Carramiñana, Isabel Gracia, Miriam Panzeri, Irene León, Jaume Balust, Ricard Navarro, María José Arguís, María José Carretero, Cristina Ibáñez, Juan Perdomo, Antonio López, Manuel López-Baamonde, Tomás Cuñat, Marta Ubré, Antonio Ojeda, Andrea Calvo, Eva Rivas, Paola Hurtado, Roger Pujol, Nuria Martín, Javier Tercero, Pepe Sanahuja, Marta Magaldi, Miquel Coca, Elena del Rio, Julia Martínez-Ocon, Paula Masgoret, Angel Caballero, Raquel Risco, Lidia Gómez, Nicolás de Riva, Ana Ruiz, Beatriz Tena, Monserrat Tio, Sebastián Jaramillo, José María Balibrea, Francisco Borja de Lacy, Ana Otero, Ainitze Ibarzabal, Raquel Bravo, Anna Carreras, Daniel Martín-Barreda, Alfonso Jesús Alias, Mariano Balaguer, Jorge Aliaga, Alex Almuedo, Joan Ramón Alonso, Rut Andrea, Gerard Sergi Angelès, Marilyn Arias, Fátima Aziz, Joan Ramon Badía, Enric Barbeta, Toni Torres, Guillem Batiste, Pau Benet, Xavi Borrat, María Borrell, Ernest Bragulat, Inmaculada Carmona, Manuel Castellà, Pedro Castro, Joan Ceravalls, Oscar Comino, Claudia Cucciniello, Clàudia De Deray, Oriol De Diego, Paula De la Matta, Marta Farrero, Javier Fernández, Sara Fernández, Anna Fernández, Miquel Ferrer, Ana Fervienza, María Tallo Forga, Daniel Forné, Clàudia Galán, Andrea Gómez, Eduard Guasch, María Hernández- Tejero, Adriana Jacas, Beltrán Jiménez, Pere Leyes, Teresa López, José Antonio Martínez, Graciela Martínez-Pallí, Jordi Mercadal, Guido Muñoz, José Muñoz, Josep María Nicolás, José Tomás Ortiz, Anna Peiró, Manuel Pérez, Esteban Poch, Margarida Pujol, Eduard Quintana, Bartomeu Ramis, Enric Reverter, Irene Rovira, Pablo Ruiz, Elena Sandoval, Stefan Schneider, Oriol Sibila, Carla Solé, Alex Soriano, Dolors Soy, M. Suárez, Adrián Téllez, Néstor David Toapanta, Antoni Torres, Xavier Urra, César Aldecoa, Alicia Bordell, Silvia Martín, Judith Andrés, Alberto Martínez Ruiz, Gonzalo Tamayo Medel, Iñaki Bilbao Villasante, Fernando Iturri Clavero, Covadonga Peralta Álvarez, Julia T. Herrera Díez, Andrea García Trancho, Iñaki Sainz Mandiola, Carmen Ruano Suarez, Angela Ruiz Bocos, Eneritz Urrutia Izagirre, Pablo Ortiz de Urbina Fernández, Naiara Apodaka López, Leire Prieto Molano, Eunate Ganuza Martínez, Iratxe Vallinas Hidalgo, Karmele de Orte Sancho, Celia González Paniagua, Gemma Ortiz Labrador, Mireia Pérez Larrañaga, Marta López Miguelez, Estíbaliz Bárcena Andrés, Erik Urutxurtu Laureano, Maria Jesús Maroño Boedo, Blanca Escontrela Rodríguez, Aitziber Ereñozaga Camiruaga, Deiene Lasuen Aguirre, Ainhoa Zabal Maeztu, Ane Guereca Gala, Iker Castelo Korro, Andrés Álvarez Campo, Alejandro Carcelen Viana, Alejandro Alberdi Enríquez, Xabier Ormazábal Rementeria, Alberto Sánchez Campos, Rosa Gutiérrez Rico, Pablo Barbier Damborenea, Marta Guerenabarrena Momeñe, Borja Cuesta Ruiz, Alejandro López Rico, Ana Rojo Polo, Covadonga García Grijelmo, Mikel Celorrio Reta, Eneko Martín Arroyo, Leire Artaza Aparicio, Iñaki Ituarte Aspiazu, Ane Igeregi Basabe, Itxaso Merino Julian, Isabel Diaz Rico, Maria Paz Martínez, Ramón Adalia, Luigi Zattera, Irina Adalid Hernández, Leire Larrañaga Altuna, Aina Serrallonga Castells, Adriana Vilchez Garcia, María Núñez, Lorena Román, Francisco Javier Redondo Calvo, Rubén Villazala González, Victor Baladron González, Patricia Faba, Omar Montenegro, Natalia Bejarano Ramírez, Sergio Marcos Contreras, Alejandro Garcia Rodríguez, Saleta Rey Vázquez, Cristina Garcia Pérez, Eva Higuera Miguelez, Irene Pérez Blanco, David García Rivera, Ane Martín de la Fuente, Marta Pardo, Vanessa Rodriguez, Unai Bengoetxea, Fernando Ramasco, Sheila Olga Santidrián Bernal, Alvar Santa Cruz Hernando, Antonio Planas Roca, Carlos Figueroa Yusta, Esther García Villabona, Carmen Vallejo Lantero, Eva Patiño Rodriguez, Alvaro Esquivel Toledo, David Arribas Méndez, Mar Orts Rodriguez, Rosa Méndez Hernández, Jesús Nieves Alonso, Inés Imaz Artazcoz, Sonia Expósito Carazo, Carlos Román Guerrero, Elena Rojo Rodríguez, Ricardo Moreno González, Julia Hernando Santos, Jara Torrente Pérez, Esperanza Mata Mena, Manuel José Muñoz Martínez, Enrique Alday Muñoz, Patricia Martin Serrano, Laura Cotter Muñoz, Amadea Mjertan, Diego Gutierrez Martínez, Carmen Rodríguez García, Olaya Alonso Viejo, Juan Alvarez Pereira, Ana Carmona Bonet, Diana Parrado López, Eva de Dios Tomas, Rafael Martín Celemin, María Luisa Meilan Paz, Luis Quecedo Gutiérrez, Noemí Diaz Velasco, Gabriel Martin Hernández, Francisco Garcia del Corral, Gloria Hernandez Arias, David Rodriguez Cuesta, Ana Gómez Rice, Encarna Mateos Sevillano, Natalia Olmos Molpeceres, Beatriz Domínguez, Ana Vázquez Lima, Ángel Candela, Ismael A. Acevedo Bambaren, Maria Isabel Albala Blanco, Paloma Alonso Montoiro, Fernando Álvarez Utrera, Juan Avellanosa Esteruelas, Amal Azzam López, Alberto José Balvis Balvis, Tommaso Bardi, María Beltrán Martín, Jacobo Benatar Haserfaty, Alberto Berruezo Camacho, Laura Betolaza Weimer, María del Mar Carbonell Soto, Cristina Carrasco Seral, Cristina Cerro Zaballos, Elizabeth Claros Llamas, Pilar Coleta Orduna, Ingrid P. Cortes Forero, Pascual Agustín Crespo Aliseda, María Angélica de Pablo Pajares, Yolanda Díez Remesal, Trinidad Dorado Díaz, Noemí Echevarría Blasco, María Elena Elías Martín, Javier Felices Triviño, Natalia Fernández López, Cristina Fernández Martín, Natalia Ferreiro Pozuelo, Luis Gajate Martín, Clara Gallego Santos, Diego Gil Mayo, María Gómez Rojo, Claudia González Cibrián, Elena Herrera López, Borja Hinojal Olmedillo, Berta Iglesias Gallego, Sassan Khonsari, María Nuria Mane Ruiz, María Manzanero Arroyo, Ana María Mariscal Ortega, Sara Martín Burcio, María del Carmen Martín González, Ascensión Martín Grande, Jose Juan Martín López, Cecilia Martín Rabes, Marcos Martínez Borja, Nilda Martínez Castro, Adolfo Martínez Pérez, Snejana Matcan, Cristina Medrano Viñas, Lisset Miguel Herrera, Adrián Mira Betancur, María Montiel Carbajo, Javier Moya Moradas, Lorena Muñoz Pérez, Mónica Nuñez Murias, Eva Ordiales González, Óscar Ordoñez Recio, Miguel Ángel Palomero Rodriguez, Diego Parise Roux, Lucia Pereira Torres, David Pestaña Lagunas, Juana María Pinto Corraliza, Marian Prieto Rodrigo, Inmaculada Rodriguez Diaz-Regaño, David Rodriguez Esteban, Víctor Rojas Pernia, Álvaro Ruigómez Saiz, Bárbara Saavedra Villarino, Noemí Samaranch Palero, Gloria Santos Pérez, Jaume Serna Pérez, Ana Belén Serrano Romero, Jesús Tercero López, Carlos Tiscar García, Marta de la Torre Concostrina, Eva María Ureta Mesa, Eva Velasco Olarte, Judith Villahoz Martínez, Raúl Villalaba Palacios, Gema Villanueva García, Cristina Vogel de Medeiros, Soraya Gholamian Ovejero, Marta Vicente Orgaz, Patricia Lloreda Herradon, Cristina Crespo Gómez, Tatiana Sarmiento-Trujillo, Noemí García Medina, María Martínez García, Carles Espinós Ramírez, Nabil Mouhaffel Rivero, Jose Antonio Bernia Gil, Sonsoles Martín, María Victoria Moral, Josefina Galán, Pilar Paniagua, Sergio Pérez, Albert Bainac, Ana Arias, Elsa Ramil, Jorge Escudero, Pablo Monedero, Carmen Cara, Andrea Lara, Elena Mendez Martínez, Jorge Mendoza, Íñigo Rubio Baines, Carmen Sala Trull, Pablo Montero López, Alfredo Gea, Alejandro Montero, Rocío Armero Ibañez, Juan Vicente Llau Pitarch, Fernando Rauer Alcóver, Cristina Álvarez Herreros, Cyntia Sánchez Martín, Lucía López Ocáriz Olmos, Marta Navas Moruno, Fernando García Montoto, Mirón Rodriguez, Laura Fuentes Coco, Cristina Hernández Gamito, Antonio Barba Orejudo, Luis Gerardo Smith Vielma, Yasmina González Marín, Francisco de Borja Amador Penco, Marta Donoso Domínguez, Silvia Esquivel Ramírez, José Antonio Carbonell, Berta Monleón López, Sara Martínez-Castro, Gerardo Aguilar, María Gestal, Pablo Casas, Angel Outeiro Rosato, Andrea Naveiro Pan, María Alonso Portela, Adrián García Romar, Eva Mosquera Rodríguez, Diego Ruanova Seijo, Pablo Rama Maceiras, Francisco Castro-Ceoane, Esther Moreno López, Sergio Gil, Julia Guillén Antón, Patricia García-Consuegra Tirado, Aurora Callau Calvo, Laura Forés Lisbona, María Carbonell Romero, Belén Albericio Gil, Laura Pradal Jarne, María Soria Lozano, Diego Loscos López, Andrea Patiño Abarca, Jordi Serrano, Javier Pérez-Asenjo, Ángel Díez-Domínguez, Ion Zubizarreta, Jon Ramos, Iosu Fernández, Emilio Maseda, Alejandro Suárez de la Rica, Javier Veganzones, Itziar Insausti, Javier Sagra, Sofía Díaz Carrasco, Ana Montero Feijoo, Julio Yagüe, Ignacio Garutti, Eva Bassas Parga, Carmen Deiros Garcia, Elisenda Pujol Rosa, Ana Tejedor Navarro, Roser Font Gabernet, Maria José Bernat, Meritxell Serra Valls, Cristina Cobaleda Garcia-Bernalt, Jesus Fernanz Anton, Adriana Aponte Sierra, Lucia Gil Gomez, Olaia Guenaga Vaqueiro, Susana Hernandez Marin, Laura Pardo Pinzon, Sira Garcia Aranda, Carlos Briones Orejuela, Edgar Cortes Sanchez, Alejandro Romero Fernandez, Esther Fernández Sanjosé, Patricia Iglesias Garsabal, Guillermo Isidro Lopez, Ana Vicol, Sara Espejo Malagon, María Sanabra Loewe, Laura Grau Torradeflo, Lourdes Blanco Alcaide, Gloria Buenaventura Sanclemente, Pere Serra Pujol, Gustavo Cuadros Mendoza, Miroslawa Konarska, Fedra Bachs Almenara, Agnieszka Golska, Aleix Carmona Blesa, Arantxa Mas Serra, Javier Ripolles Melchor, Ana Nieto Moreno, Káteri Chao Novo, Sandra Gadín López, Elena Nieto Moreno, Bérénice Gutiérrez Tonal, Elena Lucena de Pablo, Barbara Algar Yañez, Beatriz Vázquez Rivero, Beatriz Nozal Mateo, Marina de Retes, Norma Aracil Escoda, Cristina Gallardo Mayo, Rosa Sanz González, Alicia Ruiz Escobar, Maria Laura Pelegrina López, Marina Valenzuela Peña, David Stolle Dueñas, Ane Abad Motos, Alfredo Abad-Gurumeta, Ana Tirado Errazquin, Elena Sáez Ruiz, Nerea Gómez Pérez, Francisco de Borja Bau González, Cesar Morcillo Serra, Jessica Souto Higueras, Rosario Vicente, Raquel Ferrandis, Silvia Polo Martín, Azucena Pajares Moncho, Ignacio Moreno Puigdollers, Juan Pérez Artacho Cortés, Ana Moret Calvo, Ana Pi Peña, María Catalán Fernández, Marina Varela, Pilar Díaz Parada, Raquel Rey Carlín, Sarra Barreiro Aragunde, María Isabel Forés Chiva, A. Javier Agulló, Antonio Pérez Ferrer, María Galiana, Antoni Margarit, Válerie Mourre del Rio, Eva Heras Muxella, Anna Vidal
Open Access
01.12.2020 | COVID-19 | Research Letter
Biomarkers for antimicrobial stewardship: a reappraisal in COVID-19 times?
Miranda van Berkel, Matthijs Kox, Tim Frenzel, Peter Pickkers, Jeroen Schouten, Miranda van Berkel, Matthijs Kox, Tim Frenzel, Peter Pickkers, Jeroen Schouten, Denise Waanders, Niklas Bruse, Emma Kooistra, Hugo Touw, Pleun Hemelaar, Remi Beunders, Johannes van der Hoeven, Sjef van der Velde, Hetty van der Eng, Noortje Rovers, Margreet Klop-Riehl, Jelle Gerretsen, Nicole Waalders, Wout Claassen, Hidde Heesakkers, Tirsa van Schaik, Mihai Netea, Leo Joosten, Nico Janssen, Inge Grondman, Aline de Nooijer, Quirijn de Mast, Martin Jaeger, Ilse Kouijzer, Helga Dijkstra, Heidi Lemmers, Reinout van Crevel, Josephine van de Maat, Gerine Nijman, Simone Moorlag, Esther Taks, Priya Debisarun, Heiman Wertheim, Joost Hopman, Janette Rahamat-Langendoen, Chantal Bleeker-Rovers, Esther Fasse, Esther van Rijssen, Manon Kolkman, Bram van Cranenbroek, Ruben Smeets, Irma Joosten
Open Access
01.12.2020 | Research
Early hyperoxemia is associated with lower adjusted mortality after severe trauma: results from a French registry
Josefine S. Baekgaard, Paer-Selim Abback, Marouane Boubaya, Jean-Denis Moyer, Delphine Garrigue, Mathieu Raux, Benoit Champigneulle, Guillaume Dubreuil, Julien Pottecher, Philippe Laitselart, Fleur Laloum, Coralie Bloch-Queyrat, Frédéric Adnet, Catherine Paugam-Burtz, Romain Pirracchio, Anne Godier, Anatole Harrois, Thomas Geeraerts, Eric Meaudre, Sylvain Ausset, Tobias Gauss, Alain Meyer, Sophie Hamada, Arthur Neuschwander, Fabrice Cook, Helene Vinour, Jean Luc Hanouz, Arnaud Foucrier, Mathieu Boutonnet, Pascal Raclot, James Arthur, Nathalie Bruneau, Jean Cotte, Marc Leone, Gerard Audibert
Open Access
01.12.2020 | COVID-19 | Research
Blood purification therapy with a hemodiafilter featuring enhanced adsorptive properties for cytokine removal in patients presenting COVID-19: a pilot study
Gianluca Villa, Stefano Romagnoli, Silvia De Rosa, Massimiliano Greco, Marco Resta, Diego Pomarè Montin, Federico Prato, Francesco Patera, Fiorenza Ferrari, Giuseppe Rotondo, Claudio Ronco
Open Access
01.12.2020 | Editorial
Establishing a critical care network in Asia to improve care for critically ill patients in low- and middle-income countries
Abi Beane, Arjen M. Dondorp, Arshad Taqi, A. S. M. Areef Ahsan, Bharath Kumar Tirupakuzhi Vijayaraghavan, Chairrat Permpikul, Christopher Pell, David Gandy, Dilanthi Priyadarshani, Diptesh Aryal, Dong Phu Khiem, Duong Bich Thuy, Guy Thwaites, Gyan Kayastha, Ishara Udayanga, Jorge Salluh, Khamsay Detleuxay, Lakshmi Ranganathan, Lam Minh Yen, Lim Chew Har, Louise Thwaites, Madiha Hashmi, Marcus J. Schultz, Mavuto Mukaka, Meghan Leaver, Mohd Basri Mat Nor, Muhammad Hayat, Nick Day, Ramani Moonesinghe, Rashan Haniffa, Ratapum Champunot, Rebecca Inglis, Rozina Sultana, Sophie Yacoub, Steve Harris, Subhash Prasad Acharya, Swagata Tripathy, Syed Muneeb Ali, Tamilarasu Kadhiravan, Yoel Lubell
Open Access
01.12.2020 | Research
Frailty, delirium and hospital mortality of older adults admitted to intensive care: the Delirium (Deli) in ICU study
David Sanchez, Kathleen Brennan, Masar Al Sayfe, Sharon-Ann Shunker, Tony Bogdanoski, Sonja Hedges, Yu Chin Hou, Joan Lynch, Leanne Hunt, Evan Alexandrou, Manoj Saxena, Simon Abel, Ramanathan Lakshmanan, Deepak Bhonagiri, Michael J. Parr, Anders Aneman, Danielle Ni Chroinin, Kenneth M. Hillman, Steven A. Frost
Open Access
01.12.2020 | COVID-19 | Research
SARS-CoV-2 detection in the lower respiratory tract of invasively ventilated ARDS patients
Niccolò Buetti, Paul-Henri Wicky, Quentin Le Hingrat, Stéphane Ruckly, Timothy Mazzuchelli, Ambre Loiodice, Pierpaolo Trimboli, Valentina Forni Ogna, Etienne de Montmollin, Enos Bernasconi, Benoit Visseaux, Jean-François Timsit
Open Access
01.12.2020 | Research
Antibiotic-related gut dysbiosis induces lung immunodepression and worsens lung infection in mice
Rodrigue Dessein, Marvin Bauduin, Teddy Grandjean, Rémi Le Guern, Martin Figeac, Delphine Beury, Karine Faure, Christelle Faveeuw, Benoit Guery, Philippe Gosset, Eric Kipnis
Open Access
01.12.2020 | Research
Increased percentage of PD-L1+ natural killer cells predicts poor prognosis in sepsis patients: a prospective observational cohort study
Wenqiang Jiang, Xusheng Li, Miaoyun Wen, Xiaoyu Liu, Kangrong Wang, Qiaosheng Wang, Ya Li, Maohua Zhou, Mengting Liu, Bei Hu, Hongke Zeng
Open Access
01.12.2020 | Research
Cognitive phenotypes 1 month after ICU discharge in mechanically ventilated patients: a prospective observational cohort study
Sol Fernández-Gonzalo, Guillem Navarra-Ventura, Neus Bacardit, Gemma Gomà Fernández, Candelaria de Haro, Carles Subirà, Josefina López-Aguilar, Rudys Magrans, Leonardo Sarlabous, Jose Aquino Esperanza, Mercè Jodar, Montse Rué, Ana Ochagavía, Diego J. Palao, Rafael Fernández, Lluís Blanch
Open Access
01.12.2020 | Research
Recommendations for hemodynamic monitoring for critically ill children—expert consensus statement issued by the cardiovascular dynamics section of the European Society of Paediatric and Neonatal Intensive Care (ESPNIC)
Yogen Singh, Javier Urbano Villaescusa, Eduardo M. da Cruz, Shane M. Tibby, Gabriella Bottari, Rohit Saxena, Marga Guillén, Jesus Lopez Herce, Matteo Di Nardo, Corrado Cecchetti, Joe Brierley, Willem de Boode, Joris Lemson
Open Access
01.12.2020 | Research
Gravitational distribution of regional opening and closing pressures, hysteresis and atelectrauma in ARDS evaluated by electrical impedance tomography
Gaetano Scaramuzzo, Elena Spinelli, Savino Spadaro, Alessandro Santini, Donatella Tortolani, Francesca Dalla Corte, Antonio Pesenti, Carlo Alberto Volta, Giacomo Grasselli, Tommaso Mauri
Open Access
01.12.2020 | Research
Breath-synchronized electrical stimulation of the expiratory muscles in mechanically ventilated patients: a randomized controlled feasibility study and pooled analysis
Annemijn H. Jonkman, Tim Frenzel, Euan J. McCaughey, Angus J. McLachlan, Claire L. Boswell-Ruys, David W. Collins, Simon C. Gandevia, Armand R. J. Girbes, Oscar Hoiting, Matthijs Kox, Eline Oppersma, Marco Peters, Peter Pickkers, Lisanne H. Roesthuis, Jeroen Schouten, Zhong-Hua Shi, Peter H. Veltink, Heder J. de Vries, Cyndi Shannon Weickert, Carsten Wiedenbach, Yingrui Zhang, Pieter R. Tuinman, Angélique M. E. de Man, Jane E. Butler, Leo M. A. Heunks
Open Access
01.12.2020 | Research
Electroencephalographic features in patients undergoing extracorporeal membrane oxygenation
Lorenzo Peluso, Serena Rechichi, Federico Franchi, Selene Pozzebon, Sabino Scolletta, Alexandre Brasseur, Benjamin Legros, Jean-Louis Vincent, Jacques Creteur, Nicolas Gaspard, Fabio Silvio Taccone
Open Access
01.12.2020 | COVID-19 | Research
CXCL10 could drive longer duration of mechanical ventilation during COVID-19 ARDS
Mathieu Blot, Marine Jacquier, Ludwig-Serge Aho Glele, Guillaume Beltramo, Maxime Nguyen, Philippe Bonniaud, Sebastien Prin, Pascal Andreu, Belaid Bouhemad, Jean-Baptiste Bour, Christine Binquet, Lionel Piroth, Jean-Paul Pais de Barros, David Masson, Jean-Pierre Quenot, Pierre-Emmanuel Charles, François Aptel, Auguste Dargent, Marjolaine Georges, Marie Labruyère, Laurent Lagrost, Audrey Large, Serge Monier, Jean-Baptiste Roudaut, Charles Thomas
Open Access
01.12.2020 | Research
Circulating bioactive adrenomedullin as a marker of sepsis, septic shock and critical illness
Oscar H. M. Lundberg, Maria Lengquist, Martin Spångfors, Martin Annborn, Deborah Bergmann, Janin Schulte, Helena Levin, Olle Melander, Attila Frigyesi, Hans Friberg
Open Access
01.12.2020 | Research
Corticosteroid therapy for coronavirus disease 2019-related acute respiratory distress syndrome: a cohort study with propensity score analysis
Chaomin Wu, Dongni Hou, Chunling Du, Yanping Cai, Junhua Zheng, Jie Xu, Xiaoyan Chen, Cuicui Chen, Xianglin Hu, Yuye Zhang, Juan Song, Lu Wang, Yen-cheng Chao, Yun Feng, Weining Xiong, Dechang Chen, Ming Zhong, Jie Hu, Jinjun Jiang, Chunxue Bai, Xin Zhou, Jinfu Xu, Yuanlin Song, Fengyun Gong
Open Access
01.12.2020 | Research
Continuous assessment of neuro-ventilatory drive during 12 h of pressure support ventilation in critically ill patients
Rosa Di mussi, Savino Spadaro, Carlo Alberto Volta, Nicola Bartolomeo, Paolo Trerotoli, Francesco Staffieri, Luigi Pisani, Rachele Iannuzziello, Lidia Dalfino, Francesco Murgolo, Salvatore Grasso
Open Access
01.12.2020 | COVID-19 | Research
Dosing of thromboprophylaxis and mortality in critically ill COVID-19 patients
Sandra Jonmarker, Jacob Hollenberg, Martin Dahlberg, Otto Stackelberg, Jacob Litorell, Åsa H. Everhov, Hans Järnbert-Pettersson, Mårten Söderberg, Jonathan Grip, Anna Schandl, Mattias Günther, Maria Cronhjort
Open Access
01.12.2020 | Research Letter
Influence of the acuity of patients’ illness on effectiveness of early, goal-directed mobilization in the intensive care unit: a post hoc analysis
Ludwig Scheffenbichler, Bijan Teja, Flora Scheffenbichler, Manfred Blobner, Timothy Houle, Matthias Eikermann, Timothy Houle, Stefan Schaller, Karen Waak, Nicole Mazwi, Maximilian Hammer, Stephanie Grabitz, Karuna Wongtangman, Omid Azimaraghi
Open Access
01.12.2020 | Research
Antibiotic therapeutic drug monitoring in intensive care patients treated with different modalities of extracorporeal membrane oxygenation (ECMO) and renal replacement therapy: a prospective, observational single-center study
Dennis Kühn, Carlos Metz, Frederik Seiler, Holger Wehrfritz, Sophie Roth, Mohammad Alqudrah, André Becker, Hendrik Bracht, Stefan Wagenpfeil, Mathias Hoffmann, Robert Bals, Ulrich Hübner, Jürgen Geisel, Philipp M. Lepper, Sören L. Becker
Open Access
01.12.2020 | COVID-19 | Research
Severe manifestations of SARS-CoV-2 in children and adolescents: from COVID-19 pneumonia to multisystem inflammatory syndrome: a multicentre study in pediatric intensive care units in Spain
Alberto García-Salido, Juan Carlos de Carlos Vicente, Sylvia Belda Hofheinz, Joan Balcells Ramírez, María Slöcker Barrio, Inés Leóz Gordillo, Alexandra Hernández Yuste, Carmina Guitart Pardellans, Maite Cuervas-Mons Tejedor, Beatriz Huidobro Labarga, José Luís Vázquez Martínez, Míriam Gutiérrez Jimeno, Ignacio Oulego-Erróz, Javier Trastoy Quintela, Carmen Medina Monzón, Laura Medina Ramos, María Soledad Holanda Peña, Javier Gil-Antón, Clara Sorribes Ortí, José Carlos Flores González, Rosa María Hernández Palomo, Inma Sánchez Ganfornina, Emilia Fernández Romero, María García-Besteiro, Jesús López-Herce Cid, Rafael González Cortés, María Slöcker Barrio, Amaya Bustinza Arriortua, Jesús López-Herce Cid, Rafael González Cortés, Juan Carlos de Carlos Vicente, Maite Cuervas-Mons Tejedor, Pedro Pablo Oyágüez Ugidos, Iolanda Jordan, Carmina Guitart Pardellans, Sonia Sanchíz Cárdenas, Javier Gil-Antón, Belén Joyanes, Ainhoa Jiménez Olmos, Antonio Rodríguez Núñez, Javier Trastoy Quintela, Alexandra Hernández Yuste, Laura Díaz Munilla, Carlos Solís Reyes, Laura Medina Ramos, David Roca Pascual, Joan Ballcels Ramírez, Mario Sánchez Fernández, Alberto García-Salido, Inés Leóz Gordillo, Montserrat Nieto Moro, Amelia Martínez de Azagra Garde, María Ángeles García Teresa, Corsino Rey Galán, Alfredo Molina Cambra, Manuel González-Ripoll Garzón, Pepe Fernández-Cantalejo Padial, Ignacio Oulego-Erroz, Laia Vega Puyal, Daniel Moreno, Emilia Fernández Romero, María García Besteiro, José Carlos Flores González, Carmen Medina Monzón, Beatriz Huidobro Labarga, Rosa María Hernández Palomo, Cristina Calvo Monge, Francisco Fernández, Nieves González, Lorena Bermúdez Barrezueta, Cesar Villa Francisco, Ana Abril Molina, Mónica Valeron, Ramón Hernández Rastrollo, Sylvia Belda Hofheinz, Manuel Gijón Mediavilla, José Luis Vázquez Martínez, Manuel Frias, Raúl Montero Yéboles, Juan Ignacio Muñóz Bonet, María Velázquez, Inma Sánchez Ganfornina, Antonio Pérez Iranzo, David Lozano, Clara Sorribes Ortí, María Soledad Holanda Peña, Miriam Gutiérrez Jimeno
Open Access
01.12.2020 | Research
Xenon treatment after severe traumatic brain injury improves locomotor outcome, reduces acute neuronal loss and enhances early beneficial neuroinflammation: a randomized, blinded, controlled animal study
Rita Campos-Pires, Haldis Onggradito, Eszter Ujvari, Shughoofa Karimi, Flavia Valeo, Jitka Aldhoun, Christopher J. Edge, Nicholas P. Franks, Robert Dickinson
Open Access
01.12.2020 | Research
Ultrasound shear wave elastography for assessing diaphragm function in mechanically ventilated patients: a breath-by-breath analysis
Quentin Fossé, Thomas Poulard, Marie-Cécile Niérat, Sara Virolle, Elise Morawiec, Jean-Yves Hogrel, Thomas Similowski, Alexandre Demoule, Jean-Luc Gennisson, Damien Bachasson, Martin Dres
Open Access
01.12.2020 | COVID-19 | Research
Right ventricular-arterial uncoupling independently predicts survival in COVID-19 ARDS
Michele D’Alto, Alberto M. Marra, Sergio Severino, Andrea Salzano, Emanuele Romeo, Rosanna De Rosa, Francesca Maria Stagnaro, Gianpiero Pagnano, Raffaele Verde, Patrizia Murino, Andrea Farro, Giovanni Ciccarelli, Maria Vargas, Giuseppe Fiorentino, Giuseppe Servillo, Ivan Gentile, Antonio Corcione, Antonio Cittadini, Robert Naeije, Paolo Golino
Open Access
01.12.2020 | Research
Impact of advance directives on the variability between intensivists in the decisions to forgo life-sustaining treatment
Margot Smirdec, Mercé Jourdain, Virginie Guastella, Céline Lambert, Jean-Christophe Richard, Laurent Argaud, Samir Jaber, Kada Klouche, Anne Medard, Jean Reignier, Jean-Philippe Rigaud, Jean-Marc Doise, Russell Chabanne, Bertrand Souweine, Jeremy Bourenne, Julie Delmas, Pierre-Marie Bertrand, Philippe Verdier, Jean-Pierre Quenot, Cecile Aubron, Nathanael Eisenmann, Pierre Asfar, Alexandre Fratani, Jean Dellamonica, Nicolas Terzi, Jean-Michel Constantin, Axelle Van Lander, Renaud Guerin, Bruno Pereira, Alexandre Lautrette
Open Access
01.12.2020 | COVID-19 | Research
Thromboembolic complications in critically ill COVID-19 patients are associated with impaired fibrinolysis
Jan Matthias Kruse, Abakar Magomedov, Annika Kurreck, Frédéric H. Münch, Roland Koerner, Julian Kamhieh-Milz, Andreas Kahl, Inka Gotthardt, Sophie K. Piper, Kai-Uwe Eckardt, Thomas Dörner, Daniel Zickler
Open Access
01.12.2020 | COVID-19 | Research
Electrical impedance tomography to titrate positive end-expiratory pressure in COVID-19 acute respiratory distress syndrome
François Perier, Samuel Tuffet, Tommaso Maraffi, Glasiele Alcala, Marcus Victor, Anne-Fleur Haudebourg, Keyvan Razazi, Nicolas De Prost, Marcelo Amato, Guillaume Carteaux, Armand Mekontso Dessap
Open Access
01.12.2020 | Research
Transesophageal echocardiography-associated tracheal microaspiration and ventilator-associated pneumonia in intubated critically ill patients: a multicenter prospective observational study
François Bagate, Anahita Rouzé, Farid Zerimech, Florence Boissier, Vincent Labbe, Keyvan Razazi, Guillaume Carteaux, Nicolas de Prost, Malika Balduyck, Patrice Maboudou, Saad Nseir, Armand Mekontso Dessap
