01.12.2020 | Research | Ausgabe 1/2020
Open Access
Should the ultrasound probe replace your stethoscope? A SICS-I sub-study comparing lung ultrasound and pulmonary auscultation in the critically ill
Eline G. M. Cox, Geert Koster, Aidan Baron, Thomas Kaufmann, Ruben J. Eck, T. Corien Veenstra, Bart Hiemstra, Adrian Wong, Thomas C. Kwee, Jaap E. Tulleken, Frederik Keus, Renske Wiersema, Iwan C. C. van der Horst, SICS Study Group
01.12.2020 | Research | Ausgabe 1/2020
Open Access
New-onset atrial fibrillation and associated outcomes and resource use among critically ill adults—a multicenter retrospective cohort study
Shannon M. Fernando, Rebecca Mathew, Benjamin Hibbert, Bram Rochwerg, Laveena Munshi, Allan J. Walkey, Morten Hylander Møller, Trevor Simard, Pietro Di Santo, F. Daniel Ramirez, Peter Tanuseputro, Kwadwo Kyeremanteng
01.12.2020 | Research | Ausgabe 1/2020
Open Access
Effects of endovascular and surface cooling on resuscitation in patients with cardiac arrest and a comparison of effectiveness, stability, and safety: a systematic review and meta-analysis
Xueli Liao, Ziyu Zhou, Manhong Zhou, Hui Tang, Menglong Feng, Bujin Kou, Ni Zhu, Futuan Liao, Liaozhang Wu
01.12.2020 | Research | Ausgabe 1/2020
Open Access
Time to appropriate antibiotic therapy is a predictor of outcome in patients with bloodstream infection caused by KPC-producing Klebsiella pneumoniae
Marco Falcone, Matteo Bassetti, Giusy Tiseo, Cesira Giordano, Elia Nencini, Alessandro Russo, Elena Graziano, Enrico Tagliaferri, Alessandro Leonildi, Simona Barnini, Alessio Farcomeni, Francesco Menichetti
01.12.2020 | Research | Ausgabe 1/2020
Open Access
The impact of high frequency oscillatory ventilation on mortality in paediatric acute respiratory distress syndrome
Judith Ju-Ming Wong, Siqi Liu, Hongxing Dang, Nattachai Anantasit, Phuc Huu Phan, Suwannee Phumeetham, Suyun Qian, Jacqueline Soo May Ong, Chin Seng Gan, Yek Kee Chor, Rujipat Samransamruajkit, Tsee Foong Loh, Mengling Feng, Jan Hau Lee, for the Pediatric Acute & Critical care Medicine Asian Network (PACCMAN)
01.12.2020 | Research | Ausgabe 1/2020
Open Access
Impact of a posttraumatic cerebral infarction on outcome in patients with TBI: the Italian multicenter cohort INCEPT study
Nicola Latronico, Simone Piva, Nazzareno Fagoni, Lorenzo Pinelli, Michele Frigerio, Davide Tintori, Maurizio Berardino, Andrea Bottazzi, Livio Carnevale, Tiziana Casalicchio, Carlo Alberto Castioni, Simona Cavallo, Davide Cerasti, Giuseppe Citerio, Marco Fontanella, Serena Galiberti, Alan Girardini, Paolo Gritti, Ornella Manara, Paolo Maremmani, Roberta Mazzani, Giuseppe Natalini, Mirko Patassini, Maria Elena Perna, Ilaria Pesaresi, Danila Katia Radolovich, Maurizio Saini, Roberto Stefini, Cosetta Minelli, Roberto Gasparotti, Francesco A. Rasulo
01.12.2020 | Research | Ausgabe 1/2020
Open Access
Real-time shear wave ultrasound elastography: a new tool for the evaluation of diaphragm and limb muscle stiffness in critically ill patients
Aurelien Flatres, Yassir Aarab, Stephanie Nougaret, Fanny Garnier, Romaric Larcher, Mathieu Amalric, Kada Klouche, Pascal Etienne, Gilles Subra, Samir Jaber, Nicolas Molinari, Stefan Matecki, Boris Jung
01.12.2020 | Research | Ausgabe 1/2020
Open Access
Angiotensin I and angiotensin II concentrations and their ratio in catecholamine-resistant vasodilatory shock
Rinaldo Bellomo, Richard G. Wunderink, Harold Szerlip, Shane W. English, Laurence W. Busse, Adam M. Deane, Ashish K. Khanna, Michael T. McCurdy, Marlies Ostermann, Paul J. Young, Damian R. Handisides, Lakhmir S. Chawla, George F. Tidmarsh, Timothy E. Albertson
01.12.2020 | Research | Ausgabe 1/2020
Open Access
Cathelicidin preserves intestinal barrier function in polymicrobial sepsis
Jeffery Ho, Hung Chan, Yonghao Liang, Xiaodong Liu, Lin Zhang, Qing Li, Yuchen Zhang, Judeng Zeng, Felix N. Ugwu, Idy H. T. Ho, Wei Hu, Johnny C. W. Yau, Sunny H. Wong, Wai Tat Wong, Lowell Ling, Chi H. Cho, Richard L. Gallo, Tony Gin, Gary Tse, Jun Yu, Matthew T. V. Chan, Czarina C. H. Leung, William K. K. Wu
01.12.2020 | Research | Ausgabe 1/2020
Open Access
Effects of very early start of norepinephrine in patients with septic shock: a propensity score-based analysis
Gustavo A. Ospina-Tascón, Glenn Hernandez, Ingrid Alvarez, Luis E. Calderón-Tapia, Ramiro Manzano-Nunez, Alvaro I. Sánchez-Ortiz, Egardo Quiñones, Juan E. Ruiz-Yucuma, José L. Aldana, Jean-Louis Teboul, Alexandre Biasi Cavalcanti, Daniel De Backer, Jan Bakker
01.12.2020 | Research | Ausgabe 1/2020
Open Access
Intrapulmonary concentrations of meropenem administered by continuous infusion in critically ill patients with nosocomial pneumonia: a randomized pharmacokinetic trial
Adela Benítez-Cano, Sonia Luque, Luisa Sorlí, Jesús Carazo, Isabel Ramos, Nuria Campillo, Víctor Curull, Albert Sánchez-Font, Carles Vilaplana, Juan P. Horcajada, Ramón Adalia, Silvia Bermejo, Enric Samsó, William Hope, Santiago Grau
01.12.2020 | Research | Ausgabe 1/2020
Open Access
International evidence-based guidelines on Point of Care Ultrasound (POCUS) for critically ill neonates and children issued by the POCUS Working Group of the European Society of Paediatric and Neonatal Intensive Care (ESPNIC)
Yogen Singh, Cecile Tissot, María V. Fraga, Nadya Yousef, Rafael Gonzalez Cortes, Jorge Lopez, Joan Sanchez-de-Toledo, Joe Brierley, Juan Mayordomo Colunga, Dusan Raffaj, Eduardo Da Cruz, Philippe Durand, Peter Kenderessy, Hans-Joerg Lang, Akira Nishisaki, Martin C. Kneyber, Pierre Tissieres, Thomas W. Conlon, Daniele De Luca
01.12.2020 | Research | Ausgabe 1/2020
Open Access
Effects of a national quality improvement program on ICUs in China: a controlled pre-post cohort study in 586 hospitals
Huaiwu He, Xudong Ma, Longxiang Su, Lu Wang, Yanhong Guo, Guangliang Shan, Hui Jing He, Xiang Zhou, Dawei Liu, Yun Long, Yupei Zhao, Shuyang Zhang, China-NCCQC group
01.12.2020 | Research | Ausgabe 1/2020
Open Access
Efficacy, immunogenicity, and safety of IC43 recombinant Pseudomonas aeruginosa vaccine in mechanically ventilated intensive care patients—a randomized clinical trial
Christopher Adlbrecht, Raphael Wurm, Pieter Depuydt, Herbert Spapen, Jose A. Lorente, Thomas Staudinger, Jacques Creteur, Christian Zauner, Andreas Meier-Hellmann, Philipp Eller, Margot Vander Laenen, Zsolt Molnár, István Várkonyi, Bernhard Schaaf, Mária Héjja, Vladimír Šrámek, Hauke Schneider, Niranjan Kanesa-thasan, Susanne Eder-Lingelbach, Anton Klingler, Katrin Dubischar, Nina Wressnigg, Jordi Rello
01.12.2020 | Research | Ausgabe 1/2020
Open Access
Quality indicators for patients with traumatic brain injury in European intensive care units: a CENTER-TBI study
Jilske A. Huijben, Eveline J. A. Wiegers, Ari Ercole, Nicolette F. de Keizer, Andrew I. R. Maas, Ewout W. Steyerberg, Giuseppe Citerio, Lindsay Wilson, Suzanne Polinder, Daan Nieboer, David Menon, Hester F. Lingsma, Mathieu van der Jagt, the CENTER-TBI investigators and participants for the ICU stratum
01.12.2020 | Correction | Ausgabe 1/2020
Open Access
Correction to: Real-time shear wave ultrasound elastography: a new tool for the evaluation of diaphragm and limb muscle stiffness in critically ill patients
Aurelien Flatres, Yassir Aarab, Stephanie Nougaret, Fanny Garnier, Romaric Larcher, Mathieu Amalric, Kada Klouche, Pascal Etienne, Gilles Subra, Samir Jaber, Nicolas Molinari, Stefan Matecki, Boris Jung
01.12.2020 | Research | Ausgabe 1/2020
Open Access
Assisted mechanical ventilation promotes recovery of diaphragmatic thickness in critically ill patients: a prospective observational study
Alice Grassi, Daniela Ferlicca, Ermes Lupieri, Serena Calcinati, Silvia Francesconi, Vittoria Sala, Valentina Ormas, Elena Chiodaroli, Chiara Abbruzzese, Francesco Curto, Andrea Sanna, Massimo Zambon, Roberto Fumagalli, Giuseppe Foti, Giacomo Bellani
01.12.2020 | Research | Ausgabe 1/2020
Open Access
Impact of concomitant vasoactive treatment and mechanical left ventricular unloading in a porcine model of profound cardiogenic shock
Nanna L. J. Udesen, Ole K. L. Helgestad, Ann B. S. Banke, Peter H. Frederiksen, Jakob Josiassen, Lisette O. Jensen, Henrik Schmidt, Elazer R. Edelman, Brian Y. Chang, Hanne B. Ravn, Jacob E. Møller
01.12.2020 | Research | Ausgabe 1/2020
Open Access
Dynamic LTR retrotransposon transcriptome landscape in septic shock patients
Marine Mommert, Olivier Tabone, Audrey Guichard, Guy Oriol, Elisabeth Cerrato, Mélanie Denizot, Valérie Cheynet, Alexandre Pachot, Alain Lepape, Guillaume Monneret, Fabienne Venet, Karen Brengel-Pesce, Julien Textoris, François Mallet, MIPrea Study Group, REALISM Study Group
01.12.2020 | Research | Ausgabe 1/2020
Open Access
Risk factors for candidemia: a prospective matched case-control study
Julien Poissy, Lauro Damonti, Anne Bignon, Nina Khanna, Matthias Von Kietzell, Katia Boggian, Dionysios Neofytos, Fanny Vuotto, Valérie Coiteux, Florent Artru, Stephan Zimmerli, Jean-Luc Pagani, Thierry Calandra, Boualem Sendid, Daniel Poulain, Christian van Delden, Frédéric Lamoth, Oscar Marchetti, Pierre-Yves Bochud, the FUNGINOS, Allfun French Study Groups
01.12.2020 | Research | Ausgabe 1/2020
Open Access
Factors associated with the development of septic shock in patients with candidemia: a post hoc analysis from two prospective cohorts
Matteo Bassetti, Antonio Vena, Marco Meroi, Celia Cardozo, Guillermo Cuervo, Daniele Roberto Giacobbe, Miguel Salavert, Paloma Merino, Francesca Gioia, Mario Fernández-Ruiz, Luis Eduardo López-Cortés, Benito Almirante, Laura Escolà-Vergé, Miguel Montejo, Manuela Aguilar-Guisado, Pedro Puerta-Alcalde, Mariona Tasias, Alba Ruiz-Gaitán, Fernando González, Mireia Puig-Asensio, Francesc Marco, Javier Pemán, Jesus Fortún, Jose Maria Aguado, Alejandro Soriano, Jordi Carratalá, Carolina Garcia-Vidal, Maricela Valerio, Assunta Sartor, Emilio Bouza, Patricia Muñoz
01.12.2020 | Research | Ausgabe 1/2020
Open Access
Hyperoxemia and excess oxygen use in early acute respiratory distress syndrome: insights from the LUNG SAFE study
Fabiana Madotto, Emanuele Rezoagli, Tài Pham, Marcello Schmidt, Bairbre McNicholas, Alessandro Protti, Rakshit Panwar, Giacomo Bellani, Eddy Fan, Frank van Haren, Laurent Brochard, John G. Laffey, for the LUNG SAFE Investigators and the ESICM Trials Group
01.12.2020 | Research | Ausgabe 1/2020
Open Access
Long-term survival and costs following extracorporeal membrane oxygenation in critically ill children—a population-based cohort study
Shannon M. Fernando, Danial Qureshi, Peter Tanuseputro, Sonny Dhanani, Anne-Marie Guerguerian, Sam D. Shemie, Robert Talarico, Eddy Fan, Laveena Munshi, Bram Rochwerg, Damon C. Scales, Daniel Brodie, Kednapa Thavorn, Kwadwo Kyeremanteng
01.12.2020 | Review | Ausgabe 1/2020
Open Access
Brain–heart interaction after acute ischemic stroke
Denise Battaglini, Chiara Robba, Adriana Lopes da Silva, Cynthia dos Santos Samary, Pedro Leme Silva, Felipe Dal Pizzol, Paolo Pelosi, Patricia Rieken Macedo Rocco
01.12.2020 | Research | Ausgabe 1/2020
Open Access
Circulating dipeptidyl peptidase-3 at admission is associated with circulatory failure, acute kidney injury and death in severely ill burn patients
François Dépret, Juliette Amzallag, Adrien Pollina, Laure Fayolle-Pivot, Maxime Coutrot, Maïté Chaussard, Karine Santos, Oliver Hartmann, Marion Jully, Alexandre Fratani, Haikel Oueslati, Alexandru Cupaciu, Mourad Benyamina, Lucie Guillemet, Benjamin Deniau, Alexandre Mebazaa, Etienne Gayat, Boris Farny, Julien Textoris, Matthieu Legrand, for the PRONOBURN group
01.12.2020 | Research | Ausgabe 1/2020
Open Access
The clinical relevance of oliguria in the critically ill patient: analysis of a large observational database
Jean-Louis Vincent, Andrew Ferguson, Peter Pickkers, Stephan M. Jakob, Ulrich Jaschinski, Ghaleb A. Almekhlafi, Marc Leone, Majid Mokhtari, Luis E. Fontes, Philippe R. Bauer, Yasser Sakr, for the ICON Investigators
29.04.2020 | COVID-19 | Commentary | Ausgabe 1/2020
Open Access
Shining a light on the evidence for hydroxychloroquine in SARS-CoV-2
Nicholas E. Ingraham, David Boulware, Matthew A. Sparks, Timothy Schacker, Bradley Benson, Jeffrey A. Sparks, Thomas Murray, John Connett, Jeffrey G. Chipman, Anthony Charles, Christopher J. Tignanelli
01.12.2020 | Research | Ausgabe 1/2020
Open Access
Copeptin as a marker of outcome after cardiac arrest: a sub-study of the TTM trial
Joachim Düring, Martin Annborn, Tobias Cronberg, Josef Dankiewicz, Yvan Devaux, Christian Hassager, Janneke Horn, Jesper Kjaergaard, Michael Kuiper, Homa Rafi Nikoukhah, Pascal Stammet, Johan Undén, Michael Jaeger Wanscher, Matt Wise, Hans Friberg, Niklas Nielsen
01.12.2020 | Research | Ausgabe 1/2020
Open Access
Clinical course and outcome of 107 patients infected with the novel coronavirus, SARS-CoV-2, discharged from two hospitals in Wuhan, China
Dawei Wang, Yimei Yin, Chang Hu, Xing Liu, Xingguo Zhang, Shuliang Zhou, Mingzhi Jian, Haibo Xu, John Prowle, Bo Hu, Yirong Li, Zhiyong Peng
11.05.2020 | COVID-19 | Editorial | Ausgabe 1/2020
Open Access
Our recommendations for acute management of COVID-19
Francesco Mojoli, Silvia Mongodi, Anita Orlando, Eric Arisi, Marco Pozzi, Luca Civardi, Guido Tavazzi, Fausto Baldanti, Raffaele Bruno, Giorgio Antonio Iotti, COVID-19 Pavia Crisis Unit
15.05.2020 | COVID-19 | Research | Ausgabe 1/2020
Open Access
Patients with COVID-19 in 19 ICUs in Wuhan, China: a cross-sectional study
Yuan Yu, Dan Xu, Shouzhi Fu, Jun Zhang, Xiaobo Yang, Liang Xu, Jiqian Xu, Yongran Wu, Chaolin Huang, Yaqi Ouyang, Luyu Yang, Minghao Fang, Hongwen Xiao, Jing Ma, Wei Zhu, Song Hu, Quan Hu, Daoyin Ding, Ming Hu, Guochao Zhu, Weijiang Xu, Jun Guo, Jinglong Xu, Haitao Yuan, Bin Zhang, Zhui Yu, Dechang Chen, Shiying Yuan, You Shang
01.12.2020 | Research | Ausgabe 1/2020
Open Access
Neurally adjusted ventilatory assist versus pressure support ventilation: a randomized controlled feasibility trial performed in patients at risk of prolonged mechanical ventilation
Daniel J. Hadfield, Louise Rose, Fiona Reid, Victoria Cornelius, Nicholas Hart, Clare Finney, Bethany Penhaligon, Jasmine Molai, Clair Harris, Sian Saha, Harriet Noble, Emma Clarey, Leah Thompson, John Smith, Lucy Johnson, Phillip A. Hopkins, Gerrard F. Rafferty
01.12.2020 | Research | Ausgabe 1/2020
Open Access
Gastrointestinal dysfunction in the critically ill: a systematic scoping review and research agenda proposed by the Section of Metabolism, Endocrinology and Nutrition of the European Society of Intensive Care Medicine
Annika Reintam Blaser, Jean-Charles Preiser, Sonja Fruhwald, Alexander Wilmer, Jan Wernerman, Carina Benstoem, Michael P. Casaer, Joel Starkopf, Arthur van Zanten, Olav Rooyackers, Stephan M. Jakob, Cecilia I. Loudet, Danielle E. Bear, Gunnar Elke, Matthias Kott, Ingmar Lautenschläger, Jörn Schäper, Jan Gunst, Christian Stoppe, Leda Nobile, Valentin Fuhrmann, Mette M. Berger, Heleen M. Oudemans-van Straaten, Yaseen M. Arabi, Adam M. Deane, on behalf of the Working Group on Gastrointestinal Function within the Section of Metabolism, Endocrinology and Nutrition (MEN Section) of ESICM
01.12.2020 | Research | Ausgabe 1/2020
Open Access
Severe diffuse alveolar hemorrhage related to autoimmune disease: a multicenter study
Adrien Mirouse, Antoine Parrot, Vincent Audigier, Alexandre Demoule, Julien Mayaux, Guillaume Géri, Eric Mariotte, Nicolas Bréchot, Nicolas de Prost, Mathieu Vautier, Mathilde Neuville, Naïke Bigé, Etienne de Montmollin, Patrice Cacoub, Matthieu Resche-Rigon, Jacques Cadranel, David Saadoun
01.12.2020 | Research | Ausgabe 1/2020
Open Access
Hemophagocytic lymphohistiocytosis in critically ill patients: diagnostic reliability of HLH-2004 criteria and HScore
Cornelia Knaak, Peter Nyvlt, Friederike S. Schuster, Claudia Spies, Patrick Heeren, Thomas Schenk, Felix Balzer, Paul La Rosée, Gritta Janka, Frank M. Brunkhorst, Didier Keh, Gunnar Lachmann
01.12.2020 | Research | Ausgabe 1/2020
Open Access
Urine cell cycle arrest biomarkers distinguish poorly between transient and persistent AKI in early septic shock: a prospective, multicenter study
Dimitri Titeca-Beauport, Delphine Daubin, Ly Van Vong, Guillaume Belliard, Cédric Bruel, Sami Alaya, Karim Chaoui, Maud Andrieu, Isabelle Rouquette-Vincenti, Frederic Godde, Michel Pascal, Momar Diouf, Christophe Vinsonneau, Kada Klouche, Julien Maizel
01.12.2020 | Research | Ausgabe 1/2020
Open Access
Duration of antibiotic therapy in critically ill patients: a randomized controlled trial of a clinical and C-reactive protein-based protocol versus an evidence-based best practice strategy without biomarkers
Isabela Borges, Rafael Carneiro, Rafael Bergo, Larissa Martins, Enrico Colosimo, Carolina Oliveira, Saulo Saturnino, Marcus Vinícius Andrade, Cecilia Ravetti, Vandack Nobre, on behalf of NIIMI – Núcleo Interdisciplinar de Investigação em Medicina Intensiva
08.06.2020 | COVID-19 | Research Letter | Ausgabe 1/2020
Open Access
PEEP levels in COVID-19 pneumonia
Vasiliki Tsolaki, Ilias Siempos, Eleni Magira, Stelios Kokkoris, George E. Zakynthinos, Spyros Zakynthinos
01.12.2020 | Research | Ausgabe 1/2020
Open Access
Hypertonic sodium lactate improves microcirculation, cardiac function, and inflammation in a rat model of sepsis
Emmanuel Besnier, David Coquerel, Geoffrey Kouadri, Thomas Clavier, Raphael Favory, Thibault Duburcq, Olivier Lesur, Soumeya Bekri, Vincent Richard, Paul Mulder, Fabienne Tamion
22.06.2020 | COVID-19 | Review | Ausgabe 1/2020
Open Access
Prevention of thrombotic risk in hospitalized patients with COVID-19 and hemostasis monitoring
Sophie Susen, Charles Ambroise Tacquard, Alexandre Godon, Alexandre Mansour, Delphine Garrigue, Philippe Nguyen, Anne Godier, Sophie Testa, Jerrold H. Levy, Pierre Albaladejo, Yves Gruel, on behalf of GIHP and GFHT
01.12.2020 | Review | Ausgabe 1/2020
Open Access
Update of the treatment of nosocomial pneumonia in the ICU
Rafael Zaragoza, Pablo Vidal-Cortés, Gerardo Aguilar, Marcio Borges, Emili Diaz, Ricard Ferrer, Emilio Maseda, Mercedes Nieto, Francisco Xavier Nuvials, Paula Ramirez, Alejandro Rodriguez, Cruz Soriano, Javier Veganzones, Ignacio Martín-Loeches
01.12.2020 | Research | Ausgabe 1/2020
Open Access
Significance of body temperature in elderly patients with sepsis
Takashi Shimazui, Taka-aki Nakada, Keith R. Walley, Taku Oshima, Toshikazu Abe, Hiroshi Ogura, Atsushi Shiraishi, Shigeki Kushimoto, Daizoh Saitoh, Seitaro Fujishima, Toshihiko Mayumi, Yasukazu Shiino, Takehiko Tarui, Toru Hifumi, Yasuhiro Otomo, Kohji Okamoto, Yutaka Umemura, Joji Kotani, Yuichiro Sakamoto, Junichi Sasaki, Shin-ichiro Shiraishi, Kiyotsugu Takuma, Ryosuke Tsuruta, Akiyoshi Hagiwara, Kazuma Yamakawa, Tomohiko Masuno, Naoshi Takeyama, Norio Yamashita, Hiroto Ikeda, Masashi Ueyama, Satoshi Fujimi, Satoshi Gando, on behalf of the JAAM FORECAST Group
01.12.2020 | Review | Ausgabe 1/2020
Open Access
Recommendations for core critical care ultrasound competencies as a part of specialist training in multidisciplinary intensive care: a framework proposed by the European Society of Intensive Care Medicine (ESICM)
Adrian Wong, Laura Galarza, Lui Forni, Daniel De Backer, Michael Slama, Bernard Cholley, Paul Mayo, Anthony McLean, Antoine Vieillard-Baron, Daniel Lichtenstein, Giovanni Volpicelli, Robert Arntfield, Ignacio Martin-Loeches, Gizella Melania Istrate, František Duška, on behalf of ESICM Critical Care Ultrasound Group
07.07.2020 | COVID-19 | Research | Ausgabe 1/2020
Open Access
Clinical course and predictors of 60-day mortality in 239 critically ill patients with COVID-19: a multicenter retrospective study from Wuhan, China
Jiqian Xu, Xiaobo Yang, Luyu Yang, Xiaojing Zou, Yaxin Wang, Yongran Wu, Ting Zhou, Yin Yuan, Hong Qi, Shouzhi Fu, Hong Liu, Jia’an Xia, Zhengqin Xu, Yuan Yu, Ruiting Li, Yaqi Ouyang, Rui Wang, Lehao Ren, Yingying Hu, Dan Xu, Xin Zhao, Shiying Yuan, Dingyu Zhang, You Shang
01.12.2020 | Research | Ausgabe 1/2020
Open Access
Prone positioning in severe ARDS requiring extracorporeal membrane oxygenation
Jonathan Rilinger, Viviane Zotzmann, Xavier Bemtgen, Carin Schumacher, Paul M. Biever, Daniel Duerschmied, Klaus Kaier, Peter Stachon, Constantin von zur Mühlen, Manfred Zehender, Christoph Bode, Dawid L. Staudacher, Tobias Wengenmayer
01.12.2020 | Research | Ausgabe 1/2020
Open Access
The effect of short-course antibiotics on the resistance profile of colonizing gut bacteria in the ICU: a prospective cohort study
Christian Munck, Ravi U. Sheth, Edward Cuaresma, Jessica Weidler, Stephania L. Stump, Philip Zachariah, David H. Chong, Anne-Catrin Uhlemann, Julian A. Abrams, Harris H. Wang, Daniel E. Freedberg
01.12.2020 | Research | Ausgabe 1/2020
Open Access
Comparison of hydroxychloroquine, lopinavir/ritonavir, and standard of care in critically ill patients with SARS-CoV-2 pneumonia: an opportunistic retrospective analysis
Marie Lecronier, Alexandra Beurton, Sonia Burrel, Luc Haudebourg, Robin Deleris, Julien Le Marec, Sara Virolle, Safaa Nemlaghi, Côme Bureau, Pierre Mora, Martin De Sarcus, Olivier Clovet, Baptiste Duceau, Paul Henri Grisot, Marie Hélène Pari, Jérémy Arzoine, Ulrich Clarac, David Boutolleau, Mathieu Raux, Julie Delemazure, Morgane Faure, Maxens Decavele, Elise Morawiec, Julien Mayaux, Alexandre Demoule, Martin Dres
14.07.2020 | COVID-19 | Review | Ausgabe 1/2020
Open Access
Role of angiotensin-converting enzyme 2 (ACE2) in COVID-19
Wentao Ni, Xiuwen Yang, Deqing Yang, Jing Bao, Ran Li, Yongjiu Xiao, Chang Hou, Haibin Wang, Jie Liu, Donghong Yang, Yu Xu, Zhaolong Cao, Zhancheng Gao
01.12.2020 | Research | Ausgabe 1/2020
Open Access
The circular RNA landscape in specific peripheral blood mononuclear cells of critically ill patients with sepsis
Hina N. Khan, Xanthe Brands, Simona Aufiero, Arie J. Hoogendijk, Augustijn M. Klarenbeek, Tjitske S. R. van Engelen, Bastiaan W. Haak, Lonneke A. van Vught, Janneke Horn, Marcus J. Schultz, Aeilko H. Zwinderman, Tom van der Poll, Brendon P. Scicluna
01.12.2020 | Research | Ausgabe 1/2020
Open Access
Multicenter evaluation of a syndromic rapid multiplex PCR test for early adaptation of antimicrobial therapy in adult patients with pneumonia
Céline Monard, Jonathan Pehlivan, Gabriel Auger, Sophie Alviset, Alexy Tran Dinh, Paul Duquaire, Nabil Gastli, Camille d’Humières, Adel Maamar, André Boibieux, Marion Baldeyrou, Julien Loubinoux, Olivier Dauwalder, Vincent Cattoir, Laurence Armand-Lefèvre, Solen Kernéis, the ADAPT study group
20.07.2020 | COVID-19 | Research | Ausgabe 1/2020
Open Access
Development and validation of a risk factor-based system to predict short-term survival in adult hospitalized patients with COVID-19: a multicenter, retrospective, cohort study
Shuai Zhang, Mengfei Guo, Limin Duan, Feng Wu, Guorong Hu, Zhihui Wang, Qi Huang, Tingting Liao, Juanjuan Xu, Yanling Ma, Zhilei Lv, Wenjing Xiao, Zilin Zhao, Xueyun Tan, Daquan Meng, Shujing Zhang, E Zhou, Zhengrong Yin, Wei Geng, Xuan Wang, Jianchu Zhang, Jianguo Chen, Yu Zhang, Yang Jin
01.12.2020 | Research | Ausgabe 1/2020
Open Access
The effect of dexmedetomidine on vasopressor requirements in patients with septic shock: a subgroup analysis of the Sedation Practice in Intensive Care Evaluation [SPICE III] Trial
Luca Cioccari, Nora Luethi, Michael Bailey, Yahya Shehabi, Belinda Howe, Anna S. Messmer, Helena K. Proimos, Leah Peck, Helen Young, Glenn M. Eastwood, Tobias M. Merz, Jukka Takala, Stephan M. Jakob, Rinaldo Bellomo, for the ANZICS Clinical Trials Group and the SPICE III Investigators
01.12.2020 | Research | Ausgabe 1/2020
Open Access
Automated vs. conventional ventilation in the ICU: a randomized controlled crossover trial comparing blood oxygen saturation during daily nursing procedures (I-NURSING)
Jonathan Chelly, Sandie Mazerand, Sebastien Jochmans, Claire-Marie Weyer, Franck Pourcine, Olivier Ellrodt, Nathalie Thieulot-Rolin, Jean Serbource-Goguel, Oumar Sy, Ly Van Phach Vong, Mehran Monchi
23.07.2020 | COVID-19 | Review | Ausgabe 1/2020
Open Access
Nebulised heparin as a treatment for COVID-19: scientific rationale and a call for randomised evidence
Frank M. P. van Haren, Clive Page, John G. Laffey, Antonio Artigas, Marta Camprubi-Rimblas, Quentin Nunes, Roger Smith, Janis Shute, Mary Carroll, Julia Tree, Miles Carroll, Dave Singh, Tom Wilkinson, Barry Dixon
29.07.2020 | COVID-19 | Research | Ausgabe 1/2020
Open Access
Cardiac injury associated with severe disease or ICU admission and death in hospitalized patients with COVID-19: a meta-analysis and systematic review
Xinye Li, Xiandu Pan, Yanda Li, Na An, Yanfen Xing, Fan Yang, Li Tian, Jiahao Sun, Yonghong Gao, Hongcai Shang, Yanwei Xing
01.12.2020 | Research | Ausgabe 1/2020
Open Access
Artificial neural networks improve early outcome prediction and risk classification in out-of-hospital cardiac arrest patients admitted to intensive care
Jesper Johnsson, Ola Björnsson, Peder Andersson, Andreas Jakobsson, Tobias Cronberg, Gisela Lilja, Hans Friberg, Christian Hassager, Jesper Kjaergard, Matt Wise, Niklas Nielsen, Attila Frigyesi
01.12.2020 | Correction | Ausgabe 1/2020
Open Access
Correction to: Urine cell cycle arrest biomarkers distinguish poorly between transient and persistent AKI in early septic shock: a prospective, multicenter study
Dimitri Titeca-Beauport, Delphine Daubin, Ly Van Vong, Guillaume Belliard, Cédric Bruel, Sami Alaya, Karim Chaoui, Maud Andrieu, Isabelle Rouquette-Vincenti, Frederic Godde, Michel Pascal, Momar Diouf, Christophe Vinsonneau, Kada Klouche, Julien Maizel
06.08.2020 | SARS-CoV-2 | Research | Ausgabe 1/2020
Open Access
International variation in the management of severe COVID-19 patients
Elie Azoulay, Jan de Waele, Ricard Ferrer, Thomas Staudinger, Marta Borkowska, Pedro Povoa, Katerina Iliopoulou, Antonio Artigas, Stefan J. Schaller, Manu Shankar-Hari, Mariangela Pellegrini, Michael Darmon, Jozef Kesecioglu, Maurizio Cecconi
01.12.2020 | Research | Ausgabe 1/2020
Open Access
High-flow nasal cannula oxygen therapy versus non-invasive ventilation for chronic obstructive pulmonary disease patients after extubation: a multicenter, randomized controlled trial
Dingyu Tan, Joseph Harold Walline, Bingyu Ling, Yan Xu, Jiayan Sun, Bingxia Wang, Xueqin Shan, Yunyun Wang, Peng Cao, Qingcheng Zhu, Ping Geng, Jun Xu
01.12.2020 | Research | Ausgabe 1/2020
Open Access
ECCO2R therapy in the ICU: consensus of a European round table meeting
Alain Combes, Georg Auzinger, Gilles Capellier, Damien du Cheyron, Ian Clement, Guglielmo Consales, Wojciech Dabrowski, David De Bels, Francisco Javier González de Molina Ortiz, Antje Gottschalk, Matthias P. Hilty, David Pestaña, Eduardo Sousa, Redmond Tully, Jacques Goldstein, Kai Harenski
09.08.2020 | COVID-19 | Research | Ausgabe 1/2020
Open Access
Delirium and encephalopathy in severe COVID-19: a cohort analysis of ICU patients
Julie Helms, Stéphane Kremer, Hamid Merdji, Malika Schenck, François Severac, Raphaël Clere-Jehl, Antoine Studer, Mirjana Radosavljevic, Christine Kummerlen, Alexandra Monnier, Clotilde Boulay, Samira Fafi-Kremer, Vincent Castelain, Mickaël Ohana, Mathieu Anheim, Francis Schneider, Ferhat Meziani
13.08.2020 | COVID-19 | Research | Ausgabe 1/2020
Open Access
Unspecific post-mortem findings despite multiorgan viral spread in COVID-19 patients
Myriam Remmelink, Ricardo De Mendonça, Nicky D’Haene, Sarah De Clercq, Camille Verocq, Laetitia Lebrun, Philomène Lavis, Marie-Lucie Racu, Anne-Laure Trépant, Calliope Maris, Sandrine Rorive, Jean-Christophe Goffard, Olivier De Witte, Lorenzo Peluso, Jean-Louis Vincent, Christine Decaestecker, Fabio Silvio Taccone, Isabelle Salmon
01.12.2020 | Review | Ausgabe 1/2020
Open Access
Biomarkers in critical care nutrition
Christian Stoppe, Sebastian Wendt, Nilesh M. Mehta, Charlene Compher, Jean-Charles Preiser, Daren K. Heyland, Arnold S. Kristof
01.12.2020 | Research | Ausgabe 1/2020
Open Access
Incidence and outcomes of acute respiratory distress syndrome in intensive care units of mainland China: a multicentre prospective longitudinal study
Xu Huang, Ruoyang Zhang, Guohui Fan, Dawei Wu, Haining Lu, Daoxin Wang, Wang Deng, Tongwen Sun, Lihua Xing, Shaohua Liu, Shilei Wang, Ying Cai, Ye Tian, Yi Zhang, Jingen Xia, Qingyuan Zhan, the CHARDSnet group
01.12.2020 | Research | Ausgabe 1/2020
Open Access
Assessing physicians’ and nurses’ experience of dying and death in the ICU: development of the CAESAR-P and the CAESAR-N instruments
Florence Boissier, Valérie Seegers, Amélie Seguin, Stéphane Legriel, Alain Cariou, Samir Jaber, Jean-Yves Lefrant, Thomas Rimmelé, Anne Renault, Isabelle Vinatier, Armelle Mathonnet, Danielle Reuter, Olivier Guisset, Christophe Cracco, Jacques Durand-Gasselin, Béatrice Éon, Marina Thirion, Jean-Philippe Rigaud, Bénédicte Philippon-Jouve, Laurent Argaud, Renaud Chouquer, Laurent Papazian, Céline Dedrie, Hugues Georges, Eddy Lebas, Nathalie Rolin, Pierre-Edouard Bollaert, Lucien Lecuyer, Gérald Viquesnel, Marc Leone, Ludivine Chalumeau-Lemoine, Maité Garrouste-Orgeas, Elie Azoulay, Nancy Kentish-Barnes
28.08.2020 | COVID-19 | Research | Ausgabe 1/2020
Open Access
Longitudinal changes of inflammatory parameters and their correlation with disease severity and outcomes in patients with COVID-19 from Wuhan, China
Zhilin Zeng, Haijing Yu, Huilong Chen, Weipeng Qi, Liang Chen, Guang Chen, Weiming Yan, Tao Chen, Qin Ning, Meifang Han, Di Wu
31.08.2020 | COVID-19 | Research | Ausgabe 1/2020
Open Access
Respiratory physiology of COVID-19-induced respiratory failure compared to ARDS of other etiologies
Domenico Luca Grieco, Filippo Bongiovanni, Lu Chen, Luca S. Menga, Salvatore Lucio Cutuli, Gabriele Pintaudi, Simone Carelli, Teresa Michi, Flava Torrini, Gianmarco Lombardi, Gian Marco Anzellotti, Gennaro De Pascale, Andrea Urbani, Maria Grazia Bocci, Eloisa S. Tanzarella, Giuseppe Bello, Antonio M. Dell’Anna, Salvatore M. Maggiore, Laurent Brochard, Massimo Antonelli
01.12.2020 | Research | Ausgabe 1/2020
Open Access
Body-mass index and long-term risk of sepsis-related mortality: a population-based cohort study of 0.5 million Chinese adults
Li Weng, Junning Fan, Canqing Yu, Yu Guo, Zheng Bian, Yuxia Wei, Ling Yang, Yiping Chen, Huaidong Du, Liang Chang, Weiwei Gong, Junshi Chen, Zhengming Chen, Bin Du, Jun Lv, Liming Li
01.12.2020 | Review | Ausgabe 1/2020
Open Access
The importance of airway and lung microbiome in the critically ill
Ignacio Martin-Loeches, Robert Dickson, Antoni Torres, Håkan Hanberger, Jeffrey Lipman, Massimo Antonelli, Gennaro de Pascale, Fernando Bozza, Jean Louis Vincent, Srinivas Murthy, Michael Bauer, John Marshall, Catia Cilloniz, Lieuwe D. Bos
01.12.2020 | Research | Ausgabe 1/2020
Open Access
Hydrocortisone treatment is associated with a longer duration of MODS in pediatric patients with severe sepsis and immunoparalysis
Katherine E. Bline, Melissa Moore-Clingenpeel, Josey Hensley, Lisa Steele, Kristin Greathouse, Larissa Anglim, Lisa Hanson-Huber, Jyotsna Nateri, Jennifer A. Muszynski, Octavio Ramilo, Mark W. Hall
01.12.2020 | Research | Ausgabe 1/2020
Open Access
(1,3)-β-d-Glucan-based empirical antifungal interruption in suspected invasive candidiasis: a randomized trial
Gennaro De Pascale, Brunella Posteraro, Sonia D’Arrigo, Giorgia Spinazzola, Rita Gaspari, Giuseppe Bello, Luca Maria Montini, Salvatore Lucio Cutuli, Domenico Luca Grieco, Valentina Di Gravio, Giulia De Angelis, Riccardo Torelli, Elena De Carolis, Mario Tumbarello, Maurizio Sanguinetti, Massimo Antonelli
01.12.2020 | Research | Ausgabe 1/2020
Open Access
Cross-sectional study for the clinical application of extracorporeal membrane oxygenation in Mainland China, 2018
Wei Cheng, Xu-Dong Ma, Long-Xiang Su, Huai-Wu He, Lu Wang, Bo Tang, Wei Du, Yuan-kai Zhou, Hao Wang, Na Cui, Yun Long, Da-Wei Liu, Yan-Hong Guo, Ye Wang, Guang-Liang Shan, Xiang Zhou, Shu-Yang Zhang, Yu-Pei Zhao
01.12.2020 | Research | Ausgabe 1/2020
Open Access
Understanding the neuroprotective effect of tranexamic acid: an exploratory analysis of the CRASH-3 randomised trial
Amy Brenner, Antonio Belli, Rizwana Chaudhri, Timothy Coats, Lauren Frimley, Sabariah Faizah Jamaluddin, Rashid Jooma, Raoul Mansukhani, Peter Sandercock, Haleema Shakur-Still, Temitayo Shokunbi, Ian Roberts, On behalf of the CRASH-3 trial collaborators
01.12.2020 | COVID-19 | Research | Ausgabe 1/2020
Open Access
Thrombotic and haemorrhagic complications in critically ill patients with COVID-19: a multicentre observational study
Akshay Shah, Killian Donovan, Anna McHugh, Manish Pandey, Louise Aaron, Charlotte A. Bradbury, Simon J. Stanworth, Raza Alikhan, Stephen Von Kier, Keith Maher, Nicola Curry, Susan Shapiro, Matthew J. Rowland, Matt Thomas, Richard Mason, Matthew Holland, Tom Holmes, Michael Ware, Stefan Gurney, Stuart R. McKechnie
01.12.2020 | Research | Ausgabe 1/2020
Open Access
ICU admission body composition: skeletal muscle, bone, and fat effects on mortality and disability at hospital discharge—a prospective, cohort study
Ariel Jaitovich, Camille L. Dumas, Ria Itty, Hau C. Chieng, Malik M. H. S. Khan, Ali Naqvi, John Fantauzzi, Jesse B. Hall, Paul J. Feustel, Marc A. Judson
01.12.2020 | Research | Ausgabe 1/2020
Open Access
Cost-effectiveness of adrenaline for out-of-hospital cardiac arrest
Felix Achana, Stavros Petrou, Jason Madan, Kamran Khan, Chen Ji, Anower Hossain, Ranjit Lall, Anne-Marie Slowther, Charles D. Deakin, Tom Quinn, Jerry P. Nolan, Helen Pocock, Nigel Rees, Michael Smyth, Simon Gates, Dale Gardiner, Gavin D. Perkins, for the PARAMEDIC2 Collaborators
01.12.2020 | Research | Ausgabe 1/2020
Open Access
Epinephrine’s effects on cerebrovascular and systemic hemodynamics during cardiopulmonary resuscitation
Constantine D. Mavroudis, Tiffany S. Ko, Ryan W. Morgan, Lindsay E. Volk, William P. Landis, Benjamin Smood, Rui Xiao, Marco Hefti, Timothy W. Boorady, Alexandra Marquez, Michael Karlsson, Daniel J. Licht, Vinay M. Nadkarni, Robert A. Berg, Robert M. Sutton, Todd J. Kilbaugh
01.12.2020 | COVID-19 | Research | Ausgabe 1/2020
Open Access
Efficacy of tocilizumab in patients with COVID-19 ARDS undergoing noninvasive ventilation
Francesco Menzella, Matteo Fontana, Carlo Salvarani, Marco Massari, Patrizia Ruggiero, Chiara Scelfo, Chiara Barbieri, Claudia Castagnetti, Chiara Catellani, Giorgia Gibellini, Francesco Falco, Giulia Ghidoni, Francesco Livrieri, Gloria Montanari, Eleonora Casalini, Roberto Piro, Pamela Mancuso, Luca Ghidorsi, Nicola Facciolongo
01.12.2020 | COVID-19 | Research | Ausgabe 1/2020
Open Access
Awake prone positioning does not reduce the risk of intubation in COVID-19 treated with high-flow nasal oxygen therapy: a multicenter, adjusted cohort study
Carlos Ferrando, Ricard Mellado-Artigas, Alfredo Gea, Egoitz Arruti, César Aldecoa, Ramón Adalia, Fernando Ramasco, Pablo Monedero, Emilio Maseda, Gonzalo Tamayo, María L. Hernández-Sanz, Jordi Mercadal, Ascensión Martín-Grande, Robert M. Kacmarek, Jesús Villar, Fernando Suárez-Sipmann, for the COVID-19 Spanish ICU Network
01.12.2020 | Research | Ausgabe 1/2020
Open Access
Early hyperoxemia is associated with lower adjusted mortality after severe trauma: results from a French registry
Josefine S. Baekgaard, Paer-Selim Abback, Marouane Boubaya, Jean-Denis Moyer, Delphine Garrigue, Mathieu Raux, Benoit Champigneulle, Guillaume Dubreuil, Julien Pottecher, Philippe Laitselart, Fleur Laloum, Coralie Bloch-Queyrat, Frédéric Adnet, Catherine Paugam-Burtz, Traumabase® Study Group
01.12.2020 | COVID-19 | Research | Ausgabe 1/2020
Open Access
Blood purification therapy with a hemodiafilter featuring enhanced adsorptive properties for cytokine removal in patients presenting COVID-19: a pilot study
Gianluca Villa, Stefano Romagnoli, Silvia De Rosa, Massimiliano Greco, Marco Resta, Diego Pomarè Montin, Federico Prato, Francesco Patera, Fiorenza Ferrari, Giuseppe Rotondo, Claudio Ronco
01.12.2020 | Research | Ausgabe 1/2020
Open Access
Frailty, delirium and hospital mortality of older adults admitted to intensive care: the Delirium (Deli) in ICU study
David Sanchez, Kathleen Brennan, Masar Al Sayfe, Sharon-Ann Shunker, Tony Bogdanoski, Sonja Hedges, Yu Chin Hou, Joan Lynch, Leanne Hunt, Evan Alexandrou, Manoj Saxena, Simon Abel, Ramanathan Lakshmanan, Deepak Bhonagiri, Michael J. Parr, Anders Aneman, Danielle Ni Chroinin, Kenneth M. Hillman, Steven A. Frost
01.12.2020 | COVID-19 | Research | Ausgabe 1/2020
Open Access
SARS-CoV-2 detection in the lower respiratory tract of invasively ventilated ARDS patients
Niccolò Buetti, Paul-Henri Wicky, Quentin Le Hingrat, Stéphane Ruckly, Timothy Mazzuchelli, Ambre Loiodice, Pierpaolo Trimboli, Valentina Forni Ogna, Etienne de Montmollin, Enos Bernasconi, Benoit Visseaux, Jean-François Timsit
01.12.2020 | Research | Ausgabe 1/2020
Open Access
Antibiotic-related gut dysbiosis induces lung immunodepression and worsens lung infection in mice
Rodrigue Dessein, Marvin Bauduin, Teddy Grandjean, Rémi Le Guern, Martin Figeac, Delphine Beury, Karine Faure, Christelle Faveeuw, Benoit Guery, Philippe Gosset, Eric Kipnis
01.12.2020 | Research | Ausgabe 1/2020
Open Access
Increased percentage of PD-L1+ natural killer cells predicts poor prognosis in sepsis patients: a prospective observational cohort study
Wenqiang Jiang, Xusheng Li, Miaoyun Wen, Xiaoyu Liu, Kangrong Wang, Qiaosheng Wang, Ya Li, Maohua Zhou, Mengting Liu, Bei Hu, Hongke Zeng
01.12.2020 | Research | Ausgabe 1/2020
Open Access
Cognitive phenotypes 1 month after ICU discharge in mechanically ventilated patients: a prospective observational cohort study
Sol Fernández-Gonzalo, Guillem Navarra-Ventura, Neus Bacardit, Gemma Gomà Fernández, Candelaria de Haro, Carles Subirà, Josefina López-Aguilar, Rudys Magrans, Leonardo Sarlabous, Jose Aquino Esperanza, Mercè Jodar, Montse Rué, Ana Ochagavía, Diego J. Palao, Rafael Fernández, Lluís Blanch
01.12.2020 | Research | Ausgabe 1/2020
Open Access
Recommendations for hemodynamic monitoring for critically ill children—expert consensus statement issued by the cardiovascular dynamics section of the European Society of Paediatric and Neonatal Intensive Care (ESPNIC)
Yogen Singh, Javier Urbano Villaescusa, Eduardo M. da Cruz, Shane M. Tibby, Gabriella Bottari, Rohit Saxena, Marga Guillén, Jesus Lopez Herce, Matteo Di Nardo, Corrado Cecchetti, Joe Brierley, Willem de Boode, Joris Lemson
01.12.2020 | Research | Ausgabe 1/2020
Open Access
Gravitational distribution of regional opening and closing pressures, hysteresis and atelectrauma in ARDS evaluated by electrical impedance tomography
Gaetano Scaramuzzo, Elena Spinelli, Savino Spadaro, Alessandro Santini, Donatella Tortolani, Francesca Dalla Corte, Antonio Pesenti, Carlo Alberto Volta, Giacomo Grasselli, Tommaso Mauri
01.12.2020 | Research | Ausgabe 1/2020
Open Access
Breath-synchronized electrical stimulation of the expiratory muscles in mechanically ventilated patients: a randomized controlled feasibility study and pooled analysis
Annemijn H. Jonkman, Tim Frenzel, Euan J. McCaughey, Angus J. McLachlan, Claire L. Boswell-Ruys, David W. Collins, Simon C. Gandevia, Armand R. J. Girbes, Oscar Hoiting, Matthijs Kox, Eline Oppersma, Marco Peters, Peter Pickkers, Lisanne H. Roesthuis, Jeroen Schouten, Zhong-Hua Shi, Peter H. Veltink, Heder J. de Vries, Cyndi Shannon Weickert, Carsten Wiedenbach, Yingrui Zhang, Pieter R. Tuinman, Angélique M. E. de Man, Jane E. Butler, Leo M. A. Heunks
01.12.2020 | Research | Ausgabe 1/2020
Open Access
Electroencephalographic features in patients undergoing extracorporeal membrane oxygenation
Lorenzo Peluso, Serena Rechichi, Federico Franchi, Selene Pozzebon, Sabino Scolletta, Alexandre Brasseur, Benjamin Legros, Jean-Louis Vincent, Jacques Creteur, Nicolas Gaspard, Fabio Silvio Taccone
01.12.2020 | COVID-19 | Research | Ausgabe 1/2020
Open Access
CXCL10 could drive longer duration of mechanical ventilation during COVID-19 ARDS
Mathieu Blot, Marine Jacquier, Ludwig-Serge Aho Glele, Guillaume Beltramo, Maxime Nguyen, Philippe Bonniaud, Sebastien Prin, Pascal Andreu, Belaid Bouhemad, Jean-Baptiste Bour, Christine Binquet, Lionel Piroth, Jean-Paul Pais de Barros, David Masson, Jean-Pierre Quenot, Pierre-Emmanuel Charles, Pneumochondrie study group
01.12.2020 | Research | Ausgabe 1/2020
Open Access
Circulating bioactive adrenomedullin as a marker of sepsis, septic shock and critical illness
Oscar H. M. Lundberg, Maria Lengquist, Martin Spångfors, Martin Annborn, Deborah Bergmann, Janin Schulte, Helena Levin, Olle Melander, Attila Frigyesi, Hans Friberg
01.12.2020 | Research | Ausgabe 1/2020
Open Access
Corticosteroid therapy for coronavirus disease 2019-related acute respiratory distress syndrome: a cohort study with propensity score analysis
Chaomin Wu, Dongni Hou, Chunling Du, Yanping Cai, Junhua Zheng, Jie Xu, Xiaoyan Chen, Cuicui Chen, Xianglin Hu, Yuye Zhang, Juan Song, Lu Wang, Yen-cheng Chao, Yun Feng, Weining Xiong, Dechang Chen, Ming Zhong, Jie Hu, Jinjun Jiang, Chunxue Bai, Xin Zhou, Jinfu Xu, Yuanlin Song, Fengyun Gong
01.12.2020 | Research | Ausgabe 1/2020
Open Access
Continuous assessment of neuro-ventilatory drive during 12 h of pressure support ventilation in critically ill patients
Rosa Di mussi, Savino Spadaro, Carlo Alberto Volta, Nicola Bartolomeo, Paolo Trerotoli, Francesco Staffieri, Luigi Pisani, Rachele Iannuzziello, Lidia Dalfino, Francesco Murgolo, Salvatore Grasso
01.12.2020 | COVID-19 | Research | Ausgabe 1/2020
Open Access
Dosing of thromboprophylaxis and mortality in critically ill COVID-19 patients
Sandra Jonmarker, Jacob Hollenberg, Martin Dahlberg, Otto Stackelberg, Jacob Litorell, Åsa H. Everhov, Hans Järnbert-Pettersson, Mårten Söderberg, Jonathan Grip, Anna Schandl, Mattias Günther, Maria Cronhjort
01.12.2020 | Research | Ausgabe 1/2020
Open Access
Antibiotic therapeutic drug monitoring in intensive care patients treated with different modalities of extracorporeal membrane oxygenation (ECMO) and renal replacement therapy: a prospective, observational single-center study
Dennis Kühn, Carlos Metz, Frederik Seiler, Holger Wehrfritz, Sophie Roth, Mohammad Alqudrah, André Becker, Hendrik Bracht, Stefan Wagenpfeil, Mathias Hoffmann, Robert Bals, Ulrich Hübner, Jürgen Geisel, Philipp M. Lepper, Sören L. Becker
01.12.2020 | COVID-19 | Research | Ausgabe 1/2020
Open Access
Severe manifestations of SARS-CoV-2 in children and adolescents: from COVID-19 pneumonia to multisystem inflammatory syndrome: a multicentre study in pediatric intensive care units in Spain
Alberto García-Salido, Juan Carlos de Carlos Vicente, Sylvia Belda Hofheinz, Joan Balcells Ramírez, María Slöcker Barrio, Inés Leóz Gordillo, Alexandra Hernández Yuste, Carmina Guitart Pardellans, Maite Cuervas-Mons Tejedor, Beatriz Huidobro Labarga, José Luís Vázquez Martínez, Míriam Gutiérrez Jimeno, Ignacio Oulego-Erróz, Javier Trastoy Quintela, Carmen Medina Monzón, Laura Medina Ramos, María Soledad Holanda Peña, Javier Gil-Antón, Clara Sorribes Ortí, José Carlos Flores González, Rosa María Hernández Palomo, Inma Sánchez Ganfornina, Emilia Fernández Romero, María García-Besteiro, Jesús López-Herce Cid, Rafael González Cortés, the Spanish Pediatric Intensive Care Society working group on SARS-CoV-2 infection
01.12.2020 | Research | Ausgabe 1/2020
Open Access
Xenon treatment after severe traumatic brain injury improves locomotor outcome, reduces acute neuronal loss and enhances early beneficial neuroinflammation: a randomized, blinded, controlled animal study
Rita Campos-Pires, Haldis Onggradito, Eszter Ujvari, Shughoofa Karimi, Flavia Valeo, Jitka Aldhoun, Christopher J. Edge, Nicholas P. Franks, Robert Dickinson
01.12.2020 | Research | Ausgabe 1/2020
Open Access
Ultrasound shear wave elastography for assessing diaphragm function in mechanically ventilated patients: a breath-by-breath analysis
Quentin Fossé, Thomas Poulard, Marie-Cécile Niérat, Sara Virolle, Elise Morawiec, Jean-Yves Hogrel, Thomas Similowski, Alexandre Demoule, Jean-Luc Gennisson, Damien Bachasson, Martin Dres
01.12.2020 | COVID-19 | Research | Ausgabe 1/2020
Open Access
Right ventricular-arterial uncoupling independently predicts survival in COVID-19 ARDS
Michele D’Alto, Alberto M. Marra, Sergio Severino, Andrea Salzano, Emanuele Romeo, Rosanna De Rosa, Francesca Maria Stagnaro, Gianpiero Pagnano, Raffaele Verde, Patrizia Murino, Andrea Farro, Giovanni Ciccarelli, Maria Vargas, Giuseppe Fiorentino, Giuseppe Servillo, Ivan Gentile, Antonio Corcione, Antonio Cittadini, Robert Naeije, Paolo Golino
01.12.2020 | Research | Ausgabe 1/2020
Open Access
Impact of advance directives on the variability between intensivists in the decisions to forgo life-sustaining treatment
Margot Smirdec, Mercé Jourdain, Virginie Guastella, Céline Lambert, Jean-Christophe Richard, Laurent Argaud, Samir Jaber, Kada Klouche, Anne Medard, Jean Reignier, Jean-Philippe Rigaud, Jean-Marc Doise, Russell Chabanne, Bertrand Souweine, Jeremy Bourenne, Julie Delmas, Pierre-Marie Bertrand, Philippe Verdier, Jean-Pierre Quenot, Cecile Aubron, Nathanael Eisenmann, Pierre Asfar, Alexandre Fratani, Jean Dellamonica, Nicolas Terzi, Jean-Michel Constantin, Axelle Van Lander, Renaud Guerin, Bruno Pereira, Alexandre Lautrette
01.12.2020 | COVID-19 | Research | Ausgabe 1/2020
Open Access
Thromboembolic complications in critically ill COVID-19 patients are associated with impaired fibrinolysis
Jan Matthias Kruse, Abakar Magomedov, Annika Kurreck, Frédéric H. Münch, Roland Koerner, Julian Kamhieh-Milz, Andreas Kahl, Inka Gotthardt, Sophie K. Piper, Kai-Uwe Eckardt, Thomas Dörner, Daniel Zickler
01.12.2020 | COVID-19 | Research | Ausgabe 1/2020
Open Access
Electrical impedance tomography to titrate positive end-expiratory pressure in COVID-19 acute respiratory distress syndrome
François Perier, Samuel Tuffet, Tommaso Maraffi, Glasiele Alcala, Marcus Victor, Anne-Fleur Haudebourg, Keyvan Razazi, Nicolas De Prost, Marcelo Amato, Guillaume Carteaux, Armand Mekontso Dessap
01.12.2020 | Research | Ausgabe 1/2020
Open Access
Transesophageal echocardiography-associated tracheal microaspiration and ventilator-associated pneumonia in intubated critically ill patients: a multicenter prospective observational study
François Bagate, Anahita Rouzé, Farid Zerimech, Florence Boissier, Vincent Labbe, Keyvan Razazi, Guillaume Carteaux, Nicolas de Prost, Malika Balduyck, Patrice Maboudou, Saad Nseir, Armand Mekontso Dessap
01.12.2020 | Research | Ausgabe 1/2020
Open Access
Risk factors and events in the adult intensive care unit associated with pain as self-reported at the end of the intensive care unit stay
Pierre Kalfon, Mohamed Boucekine, Philippe Estagnasie, Marie-Agnès Geantot, Audrey Berric, Georges Simon, Bernard Floccard, Thomas Signouret, Mélanie Fromentin, Martine Nyunga, Juliette Audibert, Adel Ben Salah, Bénédicte Mauchien, Achille Sossou, Marion Venot, René Robert, Arnaud Follin, Anne Renault, Maïté Garrouste-Orgeas, Olivier Collange, Quentin Levrat, Isabelle Villard, Didier Thevenin, Julien Pottecher, René-Gilles Patrigeon, Nathalie Revel, Coralie Vigne, Elie Azoulay, Olivier Mimoz, Pascal Auquier, Karine Baumstarck, IPREA Study Group
01.12.2020 | COVID-19 | Research | Ausgabe 1/2020
Open Access
Anakinra treatment in critically ill COVID-19 patients: a prospective cohort study
Emma J. Kooistra, Nicole J. B. Waalders, Inge Grondman, Nico A. F. Janssen, Aline H. de Nooijer, Mihai G. Netea, Frank L. van de Veerdonk, Esther Ewalds, Johannes G. van der Hoeven, Matthijs Kox, Peter Pickkers, the RCI-COVID-19 Study Group
01.12.2020 | COVID-19 | Research | Ausgabe 1/2020
Open Access
Viral RNA load in plasma is associated with critical illness and a dysregulated host response in COVID-19
Jesús F. Bermejo-Martin, Milagros González-Rivera, Raquel Almansa, Dariela Micheloud, Ana P. Tedim, Marta Domínguez-Gil, Salvador Resino, Marta Martín-Fernández, Pablo Ryan Murua, Felipe Pérez-García, Luis Tamayo, Raúl Lopez-Izquierdo, Elena Bustamante, César Aldecoa, José Manuel Gómez, Jesús Rico-Feijoo, Antonio Orduña, Raúl Méndez, Isabel Fernández Natal, Gregoria Megías, Montserrat González-Estecha, Demetrio Carriedo, Cristina Doncel, Noelia Jorge, Alicia Ortega, Amanda de la Fuente, Félix del Campo, José Antonio Fernández-Ratero, Wysali Trapiello, Paula González-Jiménez, Guadalupe Ruiz, Alyson A. Kelvin, Ali Toloue Ostadgavahi, Ruth Oneizat, Luz María Ruiz, Iria Miguéns, Esther Gargallo, Ioana Muñoz, Sara Pelegrin, Silvia Martín, Pablo García Olivares, Jamil Antonio Cedeño, Tomás Ruiz Albi, Carolina Puertas, Jose Ángel Berezo, Gloria Renedo, Rubén Herrán, Juan Bustamante-Munguira, Pedro Enríquez, Ramón Cicuendez, Jesús Blanco, Jesica Abadia, Julia Gómez Barquero, Nuria Mamolar, Natalia Blanca-López, Luis Jorge Valdivia, Belén Fernández Caso, María Ángeles Mantecón, Anna Motos, Laia Fernandez-Barat, Ricard Ferrer, Ferrán Barbé, Antoni Torres, Rosario Menéndez, José María Eiros, David J. Kelvin
01.12.2020 | Research | Ausgabe 1/2020
Open Access
High flow nasal therapy versus noninvasive ventilation as initial ventilatory strategy in COPD exacerbation: a multicenter non-inferiority randomized trial
Andrea Cortegiani, Federico Longhini, Fabiana Madotto, Paolo Groff, Raffaele Scala, Claudia Crimi, Annalisa Carlucci, Andrea Bruni, Eugenio Garofalo, Santi Maurizio Raineri, Roberto Tonelli, Vittoria Comellini, Enrico Lupia, Luigi Vetrugno, Enrico Clini, Antonino Giarratano, Stefano Nava, Paolo Navalesi, Cesare Gregoretti, the H. F.-AECOPD study investigators
01.12.2020 | COVID-19 | Research | Ausgabe 1/2020
Open Access
Corticosteroid therapy in critically ill patients with COVID-19: a multicenter, retrospective study
Yiming Li, Qinghe Meng, Xin Rao, Binbin Wang, Xingguo Zhang, Fang Dong, Tao Yu, Zhongyi Li, Huibin Feng, Jinpeng Zhang, Xiangyang Chen, Hunian Li, Yi Cheng, Xiaoyang Hong, Xiang Wang, Yimei Yin, Zhongheng Zhang, Dawei Wang
01.12.2020 | COVID-19 | Research | Ausgabe 1/2020
Open Access
Risks of ventilator-associated pneumonia and invasive pulmonary aspergillosis in patients with viral acute respiratory distress syndrome related or not to Coronavirus 19 disease
Keyvan Razazi, Romain Arrestier, Anne Fleur Haudebourg, Brice Benelli, Guillaume Carteaux, Jean‑Winoc Decousser, Slim Fourati, Paul Louis Woerther, Frederic Schlemmer, Anais Charles-Nelson, Francoise Botterel, Nicolas de Prost, Armand Mekontso Dessap
01.12.2020 | COVID-19 | Research | Ausgabe 1/2020
Open Access
Prognostic value of bedside lung ultrasound score in patients with COVID-19
Li Ji, Chunyan Cao, Ying Gao, Wen Zhang, Yuji Xie, Yilian Duan, Shuangshuang Kong, Manjie You, Rong Ma, Lili Jiang, Jie Liu, Zhenxing Sun, Ziming Zhang, Jing Wang, Yali Yang, Qing Lv, Li Zhang, Yuman Li, Jinxiang Zhang, Mingxing Xie
01.12.2020 | Research | Ausgabe 1/2020
Open Access
Comparison of anticoagulation strategies for veno-venous ECMO support in acute respiratory failure
Benjamin Seeliger, Michael Döbler, Robert Friedrich, Klaus Stahl, Christian Kühn, Johann Bauersachs, Folkert Steinhagen, Stefan F. Ehrentraut, Jens-Christian Schewe, Christian Putensen, Tobias Welte, Marius M. Hoeper, Andreas Tiede, Sascha David, Christian Bode
01.12.2020 | COVID-19 | Review | Ausgabe 1/2020
Open Access
Multi-organ point-of-care ultrasound for COVID-19 (PoCUS4COVID): international expert consensus
Arif Hussain, Gabriele Via, Lawrence Melniker, Alberto Goffi, Guido Tavazzi, Luca Neri, Tomas Villen, Richard Hoppmann, Francesco Mojoli, Vicki Noble, Laurent Zieleskiewicz, Pablo Blanco, Irene W. Y. Ma, Mahathar Abd. Wahab, Abdulmohsen Alsaawi, Majid Al Salamah, Martin Balik, Diego Barca, Karim Bendjelid, Belaid Bouhemad, Pablo Bravo-Figueroa, Raoul Breitkreutz, Juan Calderon, Jim Connolly, Roberto Copetti, Francesco Corradi, Anthony J. Dean, André Denault, Deepak Govil, Carmela Graci, Young-Rock Ha, Laura Hurtado, Toru Kameda, Michael Lanspa, Christian B. Laursen, Francis Lee, Rachel Liu, Massimiliano Meineri, Miguel Montorfano, Peiman Nazerian, Bret P. Nelson, Aleksandar N. Neskovic, Ramon Nogue, Adi Osman, José Pazeli, Elmo Pereira-Junior, Tomislav Petrovic, Emanuele Pivetta, Jan Poelaert, Susanna Price, Gregor Prosen, Shalim Rodriguez, Philippe Rola, Colin Royse, Yale Tung Chen, Mike Wells, Adrian Wong, Wang Xiaoting, Wang Zhen, Yaseen Arabi
01.12.2020 | Editorial | Ausgabe 1/2020
Open Access
The fluid challenge
Jean-Louis Vincent, Maurizio Cecconi, Daniel De Backer
