Background
Results
Lineages of the three main Asian clades circulate in Yunnan
Temporal and spatial dynamics of RABVs in China and Southeast Asia
From | To | BF | PP** | BFsub* | PP* |
---|---|---|---|---|---|
North China | South China | *** | 39.86 | *** | 36.25 |
South China | North China | *** | 29.31 | *** | 30.06 |
North China
|
Yunnan
| *** | 9.86 | *** | 10.09 |
South China
|
Yunnan
| ** | 9.55 | ** | 10.46 |
Southeast Asia | South China | *** | 10.25 | *** | 10.82 |
Yunnan
|
Southeast Asia
| * | 1.16 | * | 1.10 |
Different sites evolved under diversifying selection in the three Asian RABV lineages
M7 | M8 | ||||
---|---|---|---|---|---|
Clade | InL | InL |
χ
2
|
P
| BranchdN/dS
|
SEA-1 | −2551.03 | −2545.39 | 5.63 | 0.06 | 0.009 |
SEA-2 & SEA-3 | −4395.09 | −4302.34 | 92.75 | <0.01 | 0.056 |
Amino acid position in the N protein | |||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
Clade | 42 | 90b,c
| 110 | 128b,c
| 135b,c
| 157 | 254 | 375b,a
| 379b,c,a
| 397 | 426b,c
|
SEA-1 | S | T | E | L | S | N | R | T | L | S | S |
SEA-2 | T | N | D | L | S | S | K | T | L | G | S |
SEA-3 | T | T | E | V | A | N | R | M | V | G | A |