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Erschienen in: Journal of Assisted Reproduction and Genetics 3/2018

30.10.2017 | Commentary

Crossing the germline: CRISPR-Cas9 and our responsibility as reproductive endocrinology and infertility physicians

verfasst von: Daniel J. Kaser, Jason M. Franasiak

Erschienen in: Journal of Assisted Reproduction and Genetics | Ausgabe 3/2018

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Excerpt

“Will it be possible to obtain son or daughter, according to specifications…?”
- Anonymous, “Conception in a Watch Glass”, 1937 [1]
Literatur
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Zurück zum Zitat Kang X, He W, Huang Y, et al. Introducing precise genetic modifications into human 3PN embryos from CRISPR/Cas-mediated genome editing. J Assist Reprod Genet. 2016;33:581–8.CrossRefPubMedPubMedCentral Kang X, He W, Huang Y, et al. Introducing precise genetic modifications into human 3PN embryos from CRISPR/Cas-mediated genome editing. J Assist Reprod Genet. 2016;33:581–8.CrossRefPubMedPubMedCentral
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Zurück zum Zitat Tang L, Zeng Y, Du H, et al. CRISPR/Cas9-mediated gene editing in human zygotes using Cas9 protein. Mol Gen Genomics. 2017;292:525–33.CrossRef Tang L, Zeng Y, Du H, et al. CRISPR/Cas9-mediated gene editing in human zygotes using Cas9 protein. Mol Gen Genomics. 2017;292:525–33.CrossRef
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Zurück zum Zitat National Academies of Sciences, Engineering, and Medicine. Human genome editing: science, ethics, and governance. Washington, DC: The National Academies Press; 2017. National Academies of Sciences, Engineering, and Medicine. Human genome editing: science, ethics, and governance. Washington, DC: The National Academies Press; 2017.
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Zurück zum Zitat Ethics committee of the American Society of Reproductive Medicine. Informed consent and the use of gametes and embryos for research: a committee opinion. Fertil and Steril. 2014;101:332–5.CrossRef Ethics committee of the American Society of Reproductive Medicine. Informed consent and the use of gametes and embryos for research: a committee opinion. Fertil and Steril. 2014;101:332–5.CrossRef
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Zurück zum Zitat Miller JC, Tan S, Qiao G, et al. A TALE nuclease for efficient genome editing. Nat Biotechnol. 2011;29:143–8.CrossRefPubMed Miller JC, Tan S, Qiao G, et al. A TALE nuclease for efficient genome editing. Nat Biotechnol. 2011;29:143–8.CrossRefPubMed
Metadaten
Titel
Crossing the germline: CRISPR-Cas9 and our responsibility as reproductive endocrinology and infertility physicians
verfasst von
Daniel J. Kaser
Jason M. Franasiak
Publikationsdatum
30.10.2017
Verlag
Springer US
Erschienen in
Journal of Assisted Reproduction and Genetics / Ausgabe 3/2018
Print ISSN: 1058-0468
Elektronische ISSN: 1573-7330
DOI
https://doi.org/10.1007/s10815-017-1075-3

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