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Erschienen in: Surgical Endoscopy 10/2012

01.10.2012 | Endoluminal Surgery

Cryorecanalization: keys to success

verfasst von: Aydın Yılmaz, Zafer Aktaş, İbrahim Onur Alici, Atalay Çağlar, Hilal Sazak, Fatma Ulus

Erschienen in: Surgical Endoscopy | Ausgabe 10/2012

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Abstract

Background

Symptomatic airway obstructions are common with endobronchial exophytic tumors and may result in lethal complications. Recently, a cryorecanalization procedure has emerged that plays a role in the immediate management of airway obstruction. This study was conducted to investigate the value of cryorecanalization for the immediate management of endobronchial obstructive pathology and to determine the factors that affect the success of the procedure.

Methods

We analyzed 40 patients with symptoms of airway obstruction who were admitted to our hospital from 2006 to 2010. Patients with exophytic stenosis due to primary bronchial or metastatic neoplasms who underwent cryorecanalization procedures were included. Patients were excluded if they had involvement of a major artery near the site of the intervention. The procedure was not performed on patients with coagulation abnormalities or thrombocyte count and aggregation problems. The data were collected retrospectively.

Results

Successful cryorecanalization was achieved in 72.5 % of patients. We found that the success rate was mainly related to the presence of the distal involvement and the older age of obstruction. Restenosis rate was 12.8 %. The mean survival time after the cryorecanalization procedure was 11 ± 12.7 months. No complications occurred in 14 patients. No severe bleeding was observed for any patients, and moderate hemorrhaging occurred in ten patients, which was stopped with an argon plasma coagulator. We experienced no intraoperative mortality.

Conclusions

Cryorecanalization is a successful and safe intervention for the immediate management of endobronchial stenosis. Appropriate patient selection and high success rates should be achieved after careful radiological assessments and with early management.
Literatur
1.
Zurück zum Zitat Cavaliere S, Venuta F, Foccoli P, Toninelli C, La Face B (1996) Endoscopic treatment of malignant airway obstructions in 2,008 patients. Chest 110:1536–1542PubMedCrossRef Cavaliere S, Venuta F, Foccoli P, Toninelli C, La Face B (1996) Endoscopic treatment of malignant airway obstructions in 2,008 patients. Chest 110:1536–1542PubMedCrossRef
2.
Zurück zum Zitat Schumann C, Hetzel M, Babiak AJ, Hetzel J, Merk T, Wibmer T et al (2010) Endobronchial tumour debulking with a flexible cryoprobe for immediate treatment of malignant stenosis. J Thorac Cardiovasc Surg 139:997–1000PubMedCrossRef Schumann C, Hetzel M, Babiak AJ, Hetzel J, Merk T, Wibmer T et al (2010) Endobronchial tumour debulking with a flexible cryoprobe for immediate treatment of malignant stenosis. J Thorac Cardiovasc Surg 139:997–1000PubMedCrossRef
3.
Zurück zum Zitat Bolliger CT, Sutedja TG, Strausz J, Freitag L (2006) Therapeutic bronchoscopy with immediate effect: laser, electrocautery, argon plasma coagulation and stents. Eur Respir J 27:1258–1271PubMedCrossRef Bolliger CT, Sutedja TG, Strausz J, Freitag L (2006) Therapeutic bronchoscopy with immediate effect: laser, electrocautery, argon plasma coagulation and stents. Eur Respir J 27:1258–1271PubMedCrossRef
4.
Zurück zum Zitat Bolliger CT, Sutedja TG, Strausz J, Freitag L (2002) ERS/ATS statement on interventional pulmonology. Eur Respir J 19:356–373PubMedCrossRef Bolliger CT, Sutedja TG, Strausz J, Freitag L (2002) ERS/ATS statement on interventional pulmonology. Eur Respir J 19:356–373PubMedCrossRef
5.
Zurück zum Zitat Vergnon JM, Huber RM, Moghissi K (2006) Place of cryotherapy, brachytherapy and photodynamic therapy in therapeutic bronchoscopy of lung cancers. Eur Respir J 28:200–218PubMedCrossRef Vergnon JM, Huber RM, Moghissi K (2006) Place of cryotherapy, brachytherapy and photodynamic therapy in therapeutic bronchoscopy of lung cancers. Eur Respir J 28:200–218PubMedCrossRef
6.
Zurück zum Zitat Schumann C, Lepper PM, Barth TFE, Moller P, Kruger S (2009) Successful immediate cryorecanalization of a simultaneous high-grade tracheal and bronchial stenosis as rare manifestations of bronchial-associated lymphoid tissue lymphoma. J Thorac Cardiovasc Surg 137:e17–e19PubMedCrossRef Schumann C, Lepper PM, Barth TFE, Moller P, Kruger S (2009) Successful immediate cryorecanalization of a simultaneous high-grade tracheal and bronchial stenosis as rare manifestations of bronchial-associated lymphoid tissue lymphoma. J Thorac Cardiovasc Surg 137:e17–e19PubMedCrossRef
7.
Zurück zum Zitat Hetzel M, Hetzel J, Schumann C, Marx N, Babiak A (2004) Cryorecanalization: a new approach for the immediate management of acute airway obstruction. J Thorac Cardiovasc Surg 127:1427–1431PubMedCrossRef Hetzel M, Hetzel J, Schumann C, Marx N, Babiak A (2004) Cryorecanalization: a new approach for the immediate management of acute airway obstruction. J Thorac Cardiovasc Surg 127:1427–1431PubMedCrossRef
8.
Zurück zum Zitat Reichle G, Freitag L, Kullmann HJ, Prenzel R, Macha HN, Farin G (2000) Argon plasma coagulation in bronchology: a new method—alternative or complementary? Pneumologie 54:508–516PubMedCrossRef Reichle G, Freitag L, Kullmann HJ, Prenzel R, Macha HN, Farin G (2000) Argon plasma coagulation in bronchology: a new method—alternative or complementary? Pneumologie 54:508–516PubMedCrossRef
9.
Zurück zum Zitat Deygas N, Froudarakis M, Ozenne G, Vergnon JM (2001) Cryotherapy in early superficial bronchogenic carcinoma. Chest 120:26–31PubMedCrossRef Deygas N, Froudarakis M, Ozenne G, Vergnon JM (2001) Cryotherapy in early superficial bronchogenic carcinoma. Chest 120:26–31PubMedCrossRef
10.
Zurück zum Zitat Herth FJ, Eberhardt R, Becker HD, Ernst A (2005) Relief of malignant airway obstruction: a prospective and randomised comparison of five different endoscopic techniques. Chest 128(4):209S Herth FJ, Eberhardt R, Becker HD, Ernst A (2005) Relief of malignant airway obstruction: a prospective and randomised comparison of five different endoscopic techniques. Chest 128(4):209S
11.
Zurück zum Zitat Mathur PN, Wolf KM, Busk MF, Briete WM, Datzman M (1996) Fiberoptic bronchoscopic cryotherapy in the management of tracheobronchial obstruction. Chest 110:718–723PubMedCrossRef Mathur PN, Wolf KM, Busk MF, Briete WM, Datzman M (1996) Fiberoptic bronchoscopic cryotherapy in the management of tracheobronchial obstruction. Chest 110:718–723PubMedCrossRef
12.
Zurück zum Zitat Hetzel J, Hetzel M, Hasel C, Moeller P, Babiak A (2008) Old meets modern: the use of traditional cryoprobes in the age of molecular biology. Respiration 76:193–197PubMedCrossRef Hetzel J, Hetzel M, Hasel C, Moeller P, Babiak A (2008) Old meets modern: the use of traditional cryoprobes in the age of molecular biology. Respiration 76:193–197PubMedCrossRef
13.
14.
Zurück zum Zitat Babiak A, Hetzel J, Krishna G, Fritz P, Moeller P, Balli T, Hetzel M (2009) Transbronchial cryobiopsy: a new tool for lung biopsies. Respiration 78:203–208PubMedCrossRef Babiak A, Hetzel J, Krishna G, Fritz P, Moeller P, Balli T, Hetzel M (2009) Transbronchial cryobiopsy: a new tool for lung biopsies. Respiration 78:203–208PubMedCrossRef
15.
Zurück zum Zitat Loo PS, Thomas SC, Nicolson MC, Fyfe MN, Kerr KM (2010) Subtyping of undifferentiated non-small cell carcinomas in bronchial biopsy specimens. J Thorac Oncol 5:442–447PubMedCrossRef Loo PS, Thomas SC, Nicolson MC, Fyfe MN, Kerr KM (2010) Subtyping of undifferentiated non-small cell carcinomas in bronchial biopsy specimens. J Thorac Oncol 5:442–447PubMedCrossRef
16.
Zurück zum Zitat Du Rand IA, Barber PV, Goldring J et al (2011) British Thoracic Society guideline for advanced diagnostic and therapeutic flexible bronchoscopy in adults. Thorax 66:iii1–iii21PubMedCrossRef Du Rand IA, Barber PV, Goldring J et al (2011) British Thoracic Society guideline for advanced diagnostic and therapeutic flexible bronchoscopy in adults. Thorax 66:iii1–iii21PubMedCrossRef
Metadaten
Titel
Cryorecanalization: keys to success
verfasst von
Aydın Yılmaz
Zafer Aktaş
İbrahim Onur Alici
Atalay Çağlar
Hilal Sazak
Fatma Ulus
Publikationsdatum
01.10.2012
Verlag
Springer-Verlag
Erschienen in
Surgical Endoscopy / Ausgabe 10/2012
Print ISSN: 0930-2794
Elektronische ISSN: 1432-2218
DOI
https://doi.org/10.1007/s00464-012-2260-1

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