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Erschienen in: Clinical Journal of Gastroenterology 2/2019

18.12.2018 | Clinical Review

Current indications and yield of endoscopic ultrasound and ancillary techniques in pancreatic cystic neoplasms

verfasst von: Federico Salom, Frédéric Prat

Erschienen in: Clinical Journal of Gastroenterology | Ausgabe 2/2019

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Abstract

An increase in the diagnosis of pancreatic cystic neoplasm has been described lately. Surgical treatment or surveillance is advised depending on the type of lesion diagnosed. The most accurate diagnostic approach is needed to make the best therapeutic decision. Endoscopic ultrasound is a very valuable tool in the evaluation of pancreatic cystic neoplasm. It generates high-quality images and allows the possibility of sampling the cystic fluid for cytology, microbiological and molecular evaluation. Even with this evaluation, the sensitivity of this approach is not always adequate. New technological resources have been developed to try to improve the diagnostic accuracy of pancreatic cystic neoplasms. The two most promising techniques are needle-based confocal laser endomicroscopy and contrast-enhanced harmonic endoscopic ultrasound. Needle-based confocal laser endomicroscopy allows a microscopic evaluation of mucosal glands and vascular pattern, to differentiate mucinous from non-mucinous lesions. Contrast-enhanced harmonic endoscopic ultrasound is used for the vascular evaluation of the microcirculation of the cyst wall and mural nodule, mainly to make the difference between malignant nodules and mucus plugs. A combination of these different diagnostic techniques can improve the diagnostic accuracy of pancreatic cystic neoplasms to offer the adequate therapeutic decision.
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Metadaten
Titel
Current indications and yield of endoscopic ultrasound and ancillary techniques in pancreatic cystic neoplasms
verfasst von
Federico Salom
Frédéric Prat
Publikationsdatum
18.12.2018
Verlag
Springer Japan
Erschienen in
Clinical Journal of Gastroenterology / Ausgabe 2/2019
Print ISSN: 1865-7257
Elektronische ISSN: 1865-7265
DOI
https://doi.org/10.1007/s12328-018-00930-2

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