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Current Osteoporosis Reports

Current Osteoporosis Reports OnlineFirst articles

08.09.2020 | Genetics (D Karasik and C Ackert-Bicknell, Section Editors)

Genetic Pleiotropy of Bone-Related Phenotypes: Insights from Osteoporosis

Osteoporosis is a common systemic skeletal disease characterized by reduced bone mass and impaired bone quality [ 1 ], leading to increased bone fragility and increased low-trauma fracture risk, especially in women and the elderly. Hip and …

29.08.2020 | Therapeutics and Medical Management (S Jan De Beur and B Clarke, Section Editors)

Bone-Targeting Systems to Systemically Deliver Therapeutics to Bone Fractures for Accelerated Healing

The 18.3 million bone fractures treated annually in the USA represent one of the greatest cost to the US healthcare system (176.1 billion dollars annually) [ 1 ] and result in over 216.5 million days of work lost. Patients with comorbidities (e.g. …

26.08.2020 | Regenerative Biology and Medicine in Osteoporosis (S Bryant and M Krebs, Section Editors)

Bone-Specific Drug Delivery for Osteoporosis and Rare Skeletal Disorders

Bone has many functions in the body, such as supporting the body structure and movement, protecting organs, regulating mineral homeostasis, and providing bone marrow cells which are differentiated to leukocytes, red blood cells, and platelets. The …

22.08.2020 | Orthopedic Management of Fractures (M Kacena and L Gerstenfeld, Section Editors)

Assessment, Quantification, and Management of Fracture Pain: from Animals to the Clinic

Fractures are painful and disabling injuries that can occur at any age but are particularly prevalent in 40–50% of women and 13–22% of men with osteoporosis [ 1 , 2 ]. The number of patients in the USA with osteoporosis or low bone density will …

13.08.2020 | Osteocytes (J Delgado-Calle and J Klein-Nulend, Section Editors)

New and Old Osteocytic Cell Lines and 3D Models

The last decade has seen an expansion in the tools and models available to study skeletal processes and the establishment of new cell lines has proven fundamental in the discovery of novel therapeutics for skeletal diseases. Historically …

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Current Osteoporosis Reports provides in-depth review articles contributed by international experts on the most significant developments in the field. By presenting clear, insightful, balanced reviews that emphasize recently published papers of major importance, the journal elucidates current and emerging approaches to the diagnosis, treatment, management, and prevention of osteoporosis.

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