Skip to main content
Erschienen in: Current Urology Reports 3/2012

01.06.2012 | Endourology (V Bird, Section Editor)

Current Status of Salvage Robot-Assisted Laparoscopic Prostatectomy for Radiorecurrent Prostate Cancer

verfasst von: Bernardo Rocco, Gabriele Cozzi, Matteo Giulio Spinelli, Angelica Grasso, Daniela Varisco, Rafael F. Coelho, Vipul R. Patel

Erschienen in: Current Urology Reports | Ausgabe 3/2012

Einloggen, um Zugang zu erhalten

Abstract

Radiation therapy (RT) is one of the treatment options for prostate cancer (PCa). Transperineal low–dose rate brachytherapy (BT) is another safe and effective technique for low-risk PCa. Recurrence after RT for localized PCa can be defined by a PSA value of 2 ng/mL above the nadir after RT, and biochemical recurrence (BCR) rate after RT is 40–60 %. In case of radiorecurrent PCa, treatment options include salvage radical prostatectomy (RP), cryotherapy, high-intensity focused ultrasound (HIFU), and salvage BT. Only salvage RP has cancer control results for over 10-year follow-up in a substantial portion of patients (30–40 %). However, salvage RP is technically demanding, and experienced surgeons are needed; in fact, RT-induced cystitis, fibrosis, and tissue plane obliteration can lead to significant complications, such as rectal injuries, anastomotic stricture, and urinary incontinence. This review describes indications, oncologic and functional outcomes, surgical techniques, and complications of salvage robot-assisted RP.
Literatur
1.
Zurück zum Zitat Heidenreich A, Bellmunt J, Bolla M, et al. EAU guidelines on prostate cancer. Part 1: screening, diagnosis, and treatment of clinically localised disease. Eur Urol. 2011;59(1):61–71.PubMedCrossRef Heidenreich A, Bellmunt J, Bolla M, et al. EAU guidelines on prostate cancer. Part 1: screening, diagnosis, and treatment of clinically localised disease. Eur Urol. 2011;59(1):61–71.PubMedCrossRef
2.
Zurück zum Zitat Roach 3rd M, Hanks G, Thames Jr H, et al. Defining biochemical failure following radiotherapy with or without hormonal therapy in men with clinically localized prostate cancer: recommendations of the RTOG-ASTRO Phoenix Consensus Conference. Int J Radiat Oncol Biol Phys. 2006;65(4):965–74.PubMedCrossRef Roach 3rd M, Hanks G, Thames Jr H, et al. Defining biochemical failure following radiotherapy with or without hormonal therapy in men with clinically localized prostate cancer: recommendations of the RTOG-ASTRO Phoenix Consensus Conference. Int J Radiat Oncol Biol Phys. 2006;65(4):965–74.PubMedCrossRef
3.
Zurück zum Zitat Mottet N, Bellmunt J, Bolla M, et al. EAU guidelines on prostate cancer. Part II: treatment of advanced, relapsing, and castration-resistant prostate cancer. Eur Urol. 2011;59(4):572–83.PubMedCrossRef Mottet N, Bellmunt J, Bolla M, et al. EAU guidelines on prostate cancer. Part II: treatment of advanced, relapsing, and castration-resistant prostate cancer. Eur Urol. 2011;59(4):572–83.PubMedCrossRef
4.
Zurück zum Zitat Grossfeld GD, Li YP, Lubeck DP, Broering JM, et al. Predictors of secondary cancer treatment in patients receiving local therapy for prostate cancer: data from cancer of the prostate strategic urologic research endeavor. J Urol. 2002;168(2):530–5.PubMedCrossRef Grossfeld GD, Li YP, Lubeck DP, Broering JM, et al. Predictors of secondary cancer treatment in patients receiving local therapy for prostate cancer: data from cancer of the prostate strategic urologic research endeavor. J Urol. 2002;168(2):530–5.PubMedCrossRef
5.
Zurück zum Zitat Agarwal PK, Sadetsky N, Konety BR, et al. Treatment failure after primary and salvage therapy for prostate cancer: likelihood, patterns of care, and outcomes. Cancer. 2008;112(2):307–14.PubMedCrossRef Agarwal PK, Sadetsky N, Konety BR, et al. Treatment failure after primary and salvage therapy for prostate cancer: likelihood, patterns of care, and outcomes. Cancer. 2008;112(2):307–14.PubMedCrossRef
6.
Zurück zum Zitat Eandi JA, Link BA, Nelson RA, et al. Robotic assisted laparoscopic salvage prostatectomy for radiation resistant prostate cancer. J Urol. 2010;183(1):133–7.PubMedCrossRef Eandi JA, Link BA, Nelson RA, et al. Robotic assisted laparoscopic salvage prostatectomy for radiation resistant prostate cancer. J Urol. 2010;183(1):133–7.PubMedCrossRef
7.
Zurück zum Zitat •• Kimura M, Mouraviev V, Tsivian M, et al. Current salvage methods for recurrent prostate cancer after failure of primary radiotherapy. BJU Int. 2010;105(2):191–201. This article gives a synoptic view of the different salvage options, highlighting that only salvage RP can give cancer control for over 10 years.PubMedCrossRef •• Kimura M, Mouraviev V, Tsivian M, et al. Current salvage methods for recurrent prostate cancer after failure of primary radiotherapy. BJU Int. 2010;105(2):191–201. This article gives a synoptic view of the different salvage options, highlighting that only salvage RP can give cancer control for over 10 years.PubMedCrossRef
8.
Zurück zum Zitat Mador DR, Huben RP, Wajsman Z, et al. Salvage surgery following radical radiotherapy for adenocarcinoma of the prostate. J Urol. 1985;133(1):58–60.PubMed Mador DR, Huben RP, Wajsman Z, et al. Salvage surgery following radical radiotherapy for adenocarcinoma of the prostate. J Urol. 1985;133(1):58–60.PubMed
9.
Zurück zum Zitat Touma NJ, Izawa JI, Chin JL. Current status of local salvage therapies following radiation failure for prostate cancer. J Urol. 2005;173(2):373–9.PubMedCrossRef Touma NJ, Izawa JI, Chin JL. Current status of local salvage therapies following radiation failure for prostate cancer. J Urol. 2005;173(2):373–9.PubMedCrossRef
10.
Zurück zum Zitat Galosi AB, Lugnani F, Muzzonigro G. Salvage cryosurgery for recurrent prostate carcinoma after radiotherapy. J Endourol. 2007;21(1):1–7.PubMedCrossRef Galosi AB, Lugnani F, Muzzonigro G. Salvage cryosurgery for recurrent prostate carcinoma after radiotherapy. J Endourol. 2007;21(1):1–7.PubMedCrossRef
11.
Zurück zum Zitat Ismail M, Ahmed S, Kastner C, et al. Salvage cryotherapy for recurrent prostate cancer after radiation failure: a prospective case series of the first 100 patients. BJU Int. 2007;100(4):760–4.PubMedCrossRef Ismail M, Ahmed S, Kastner C, et al. Salvage cryotherapy for recurrent prostate cancer after radiation failure: a prospective case series of the first 100 patients. BJU Int. 2007;100(4):760–4.PubMedCrossRef
12.
Zurück zum Zitat D’Amico AV. Combined-modality staging for localized adenocarcinoma of the prostate. Oncology (Williston Park). 2001;15(8):1049–59. D’Amico AV. Combined-modality staging for localized adenocarcinoma of the prostate. Oncology (Williston Park). 2001;15(8):1049–59.
13.
Zurück zum Zitat Murat FJ, Poissonnier L, Rabilloud M, et al. Mid-term results demonstrate salvage high-intensity focused ultrasound (HIFU) as an effective and acceptably morbid salvage treatment option for locally radiorecurrent prostate cancer. Eur Urol. 2009;55(3):640–7.PubMedCrossRef Murat FJ, Poissonnier L, Rabilloud M, et al. Mid-term results demonstrate salvage high-intensity focused ultrasound (HIFU) as an effective and acceptably morbid salvage treatment option for locally radiorecurrent prostate cancer. Eur Urol. 2009;55(3):640–7.PubMedCrossRef
14.
Zurück zum Zitat Rebillard X, Soulié M, Chartier-Kastler E, et al. High-intensity focused ultrasound in prostate cancer; a systematic literature review of the French Association of Urology. BJU Int. 2008;101(10):1205–13.PubMedCrossRef Rebillard X, Soulié M, Chartier-Kastler E, et al. High-intensity focused ultrasound in prostate cancer; a systematic literature review of the French Association of Urology. BJU Int. 2008;101(10):1205–13.PubMedCrossRef
15.
Zurück zum Zitat Chalasani V, Martinez CH, Lim D, et al. Salvage HIFU for recurrent prostate cancer after radiotherapy. Prostate Cancer Prostatic Dis. 2009;12(2):124–9.PubMedCrossRef Chalasani V, Martinez CH, Lim D, et al. Salvage HIFU for recurrent prostate cancer after radiotherapy. Prostate Cancer Prostatic Dis. 2009;12(2):124–9.PubMedCrossRef
16.
Zurück zum Zitat Aaronson DS, Yamasaki I, Gottschalk A, et al. Salvage permanent perineal radioactive-seed implantation for treating recurrence of localized prostate adenocarcinoma after external beam radiotherapy. BJU Int. 2009;104(5):600–4.PubMedCrossRef Aaronson DS, Yamasaki I, Gottschalk A, et al. Salvage permanent perineal radioactive-seed implantation for treating recurrence of localized prostate adenocarcinoma after external beam radiotherapy. BJU Int. 2009;104(5):600–4.PubMedCrossRef
17.
Zurück zum Zitat Williams SB, Hu JC. Salvage robotic assisted laparoscopic radical prostatectomy: indications and outcomes. World J Urol. 2010 Nov 21. Williams SB, Hu JC. Salvage robotic assisted laparoscopic radical prostatectomy: indications and outcomes. World J Urol. 2010 Nov 21.
18.
Zurück zum Zitat Nguyen PL, D'Amico AV, Lee AK, et al. Patient selection, cancer control, and complications after salvage local therapy for postradiation prostate-specific antigen failure: a systematic review of the literature. Cancer. 2007;110(7):1417–28.PubMedCrossRef Nguyen PL, D'Amico AV, Lee AK, et al. Patient selection, cancer control, and complications after salvage local therapy for postradiation prostate-specific antigen failure: a systematic review of the literature. Cancer. 2007;110(7):1417–28.PubMedCrossRef
19.
Zurück zum Zitat Bostwick DG, Egbert BM, Fajardo LF. Radiation injury of the normal and neoplastic prostate. Am J Surg Pathol. 1982;6(6):541–51.PubMedCrossRef Bostwick DG, Egbert BM, Fajardo LF. Radiation injury of the normal and neoplastic prostate. Am J Surg Pathol. 1982;6(6):541–51.PubMedCrossRef
20.
Zurück zum Zitat Zagars GK, Pollack A. Kinetics of serum prostate-specific antigen after external beam radiation for clinically localized prostate cancer. Radiother Oncol. 1997;44(3):213–21.PubMedCrossRef Zagars GK, Pollack A. Kinetics of serum prostate-specific antigen after external beam radiation for clinically localized prostate cancer. Radiother Oncol. 1997;44(3):213–21.PubMedCrossRef
21.
Zurück zum Zitat Freedland SJ, Humphreys EB, Mangold LA, et al. Risk of prostate cancer-specific mortality following biochemical recurrence after radical prostatectomy. JAMA. 2005;294(4):433–9.PubMedCrossRef Freedland SJ, Humphreys EB, Mangold LA, et al. Risk of prostate cancer-specific mortality following biochemical recurrence after radical prostatectomy. JAMA. 2005;294(4):433–9.PubMedCrossRef
22.
Zurück zum Zitat Zelefsky MJ, Ben-Porat L, Scher HI, et al. Outcome predictors for the increasing PSA state after definitive external-beam radiotherapy for prostate cancer. J Clin Oncol. 2005;23(4):826–31.PubMedCrossRef Zelefsky MJ, Ben-Porat L, Scher HI, et al. Outcome predictors for the increasing PSA state after definitive external-beam radiotherapy for prostate cancer. J Clin Oncol. 2005;23(4):826–31.PubMedCrossRef
23.
Zurück zum Zitat Rogers E, Ohori M, Kassabian VS, et al. Salvage radical prostatectomy: outcome measured by serum prostate specific antigen levels. J Urol. 1995;153(1):104–10.PubMedCrossRef Rogers E, Ohori M, Kassabian VS, et al. Salvage radical prostatectomy: outcome measured by serum prostate specific antigen levels. J Urol. 1995;153(1):104–10.PubMedCrossRef
24.
Zurück zum Zitat Chen BT, Wood Jr DP. Salvage prostatectomy in patients who have failed radiation therapy or cryotherapy as primary treatment for prostate cancer. Urology. 2003;62 Suppl 1:69–78.PubMedCrossRef Chen BT, Wood Jr DP. Salvage prostatectomy in patients who have failed radiation therapy or cryotherapy as primary treatment for prostate cancer. Urology. 2003;62 Suppl 1:69–78.PubMedCrossRef
25.
Zurück zum Zitat Bochner BH, Figueroa AJ, Skinner EC, et al. Salvage radical cystoprostatectomy and orthotopic urinary diversion following radiation failure. J Urol. 1998;160(1):29–33.PubMedCrossRef Bochner BH, Figueroa AJ, Skinner EC, et al. Salvage radical cystoprostatectomy and orthotopic urinary diversion following radiation failure. J Urol. 1998;160(1):29–33.PubMedCrossRef
26.
Zurück zum Zitat Stephenson AJ, Eastham JA. Role of salvage radical prostatectomy for recurrent prostate cancer after radiation therapy. J Clin Oncol. 2005;23(32):8198–203.PubMedCrossRef Stephenson AJ, Eastham JA. Role of salvage radical prostatectomy for recurrent prostate cancer after radiation therapy. J Clin Oncol. 2005;23(32):8198–203.PubMedCrossRef
27.
Zurück zum Zitat Bianco Jr FJ, Scardino PT, Stephenson AJ, et al. Long-term oncologic results of salvage radical prostatectomy for locally recurrent prostate cancer after radiotherapy. Int J Radiat Oncol Biol Phys. 2005;62(2):448–53.PubMedCrossRef Bianco Jr FJ, Scardino PT, Stephenson AJ, et al. Long-term oncologic results of salvage radical prostatectomy for locally recurrent prostate cancer after radiotherapy. Int J Radiat Oncol Biol Phys. 2005;62(2):448–53.PubMedCrossRef
28.
Zurück zum Zitat Paparel P, Cronin AM, Savage C, et al. Oncologic outcome and patterns of recurrence after salvage radical prostatectomy. Eur Urol. 2009;55(2):404–10.PubMedCrossRef Paparel P, Cronin AM, Savage C, et al. Oncologic outcome and patterns of recurrence after salvage radical prostatectomy. Eur Urol. 2009;55(2):404–10.PubMedCrossRef
29.
Zurück zum Zitat Chade DC, Shariat SF, Cronin AM, et al. Salvage radical prostatectomy for radiation-recurrent prostate cancer: a multi-institutional collaboration. Eur Urol. 2011;60(2):205–10.PubMedCrossRef Chade DC, Shariat SF, Cronin AM, et al. Salvage radical prostatectomy for radiation-recurrent prostate cancer: a multi-institutional collaboration. Eur Urol. 2011;60(2):205–10.PubMedCrossRef
30.
Zurück zum Zitat Gotto GT, Yunis LH, Vora K, et al. Impact of prior prostate radiation on complications after radical prostatectomy. J Urol. 2010;184(1):136–42.PubMedCrossRef Gotto GT, Yunis LH, Vora K, et al. Impact of prior prostate radiation on complications after radical prostatectomy. J Urol. 2010;184(1):136–42.PubMedCrossRef
31.
Zurück zum Zitat Vallancien G, Gupta R, Cathelineau X, et al. Initial results of salvage laparoscopic radical prostatectomy after radiation failure. J Urol. 2003;170(5):1838–40.PubMedCrossRef Vallancien G, Gupta R, Cathelineau X, et al. Initial results of salvage laparoscopic radical prostatectomy after radiation failure. J Urol. 2003;170(5):1838–40.PubMedCrossRef
32.
Zurück zum Zitat Stolzenburg JU, Bynens B, Do M, et al. Salvage laparoscopic extraperitoneal radical prostatectomy after failed high-intensity focused ultrasound and radiotherapy for localized prostate cancer. Urology. 2007;70(5):956–60.PubMedCrossRef Stolzenburg JU, Bynens B, Do M, et al. Salvage laparoscopic extraperitoneal radical prostatectomy after failed high-intensity focused ultrasound and radiotherapy for localized prostate cancer. Urology. 2007;70(5):956–60.PubMedCrossRef
33.
Zurück zum Zitat Liatsikos E, Bynens B, Rabenalt R, et al. Treatment of patients after failed high intensity focused ultrasound and radiotherapy for localized prostate cancer: salvage laparoscopic extraperitoneal radical prostatectomy. J Endourol. 2008;22(10):2295–8.PubMedCrossRef Liatsikos E, Bynens B, Rabenalt R, et al. Treatment of patients after failed high intensity focused ultrasound and radiotherapy for localized prostate cancer: salvage laparoscopic extraperitoneal radical prostatectomy. J Endourol. 2008;22(10):2295–8.PubMedCrossRef
34.
Zurück zum Zitat Jamal K, Challacombe B, Elhage O, et al. Successful salvage robotic-assisted radical prostatectomy after external beam radiotherapy failure. Urology. 2008;72(6):1356–8.PubMedCrossRef Jamal K, Challacombe B, Elhage O, et al. Successful salvage robotic-assisted radical prostatectomy after external beam radiotherapy failure. Urology. 2008;72(6):1356–8.PubMedCrossRef
35.
Zurück zum Zitat Kaouk JH, Hafron J, Goel R, et al. Robotic salvage retropubic prostatectomy after radiation/brachytherapy: initial results. BJU Int. 2008;102(1):93–6.PubMedCrossRef Kaouk JH, Hafron J, Goel R, et al. Robotic salvage retropubic prostatectomy after radiation/brachytherapy: initial results. BJU Int. 2008;102(1):93–6.PubMedCrossRef
36.
Zurück zum Zitat Boris RS, Bhandari A, Krane LS, et al. Salvage robotic-assisted radical prostatectomy: initial results and early report of outcomes. BJU Int. 2009;103(7):952–6.PubMedCrossRef Boris RS, Bhandari A, Krane LS, et al. Salvage robotic-assisted radical prostatectomy: initial results and early report of outcomes. BJU Int. 2009;103(7):952–6.PubMedCrossRef
37.
Zurück zum Zitat Strope SA, Coelho M, Wood DP, et al. Robot-assisted salvage prostatectomy: evaluation of initial patient-reported outcomes. J Endourol. 2010;24(3):425–7.PubMedCrossRef Strope SA, Coelho M, Wood DP, et al. Robot-assisted salvage prostatectomy: evaluation of initial patient-reported outcomes. J Endourol. 2010;24(3):425–7.PubMedCrossRef
38.
Zurück zum Zitat Chauhan S, Patel MB, Coelho R, et al. Preliminary analysis of the feasibility and safety of salvage robot-assisted radical prostatectomy after radiation failure: multi-institutional perioperative and short-term functional outcomes. J Endourol. 2011;25(6):1013–9.PubMedCrossRef Chauhan S, Patel MB, Coelho R, et al. Preliminary analysis of the feasibility and safety of salvage robot-assisted radical prostatectomy after radiation failure: multi-institutional perioperative and short-term functional outcomes. J Endourol. 2011;25(6):1013–9.PubMedCrossRef
39.
Zurück zum Zitat Dindo D, Demartines N, Clavien PA. Classification of surgical complications: a new proposal with evaluation in a cohort of 6336 patients and results of a survey. Ann Surg. 2004;240(2):205–13.PubMedCrossRef Dindo D, Demartines N, Clavien PA. Classification of surgical complications: a new proposal with evaluation in a cohort of 6336 patients and results of a survey. Ann Surg. 2004;240(2):205–13.PubMedCrossRef
40.
Zurück zum Zitat Hegarty NJ, Kaouk JH. Radical prostatectomy: a comparison of open, laparoscopic and robot-assisted laparoscopic techniques. Can J Urol. 2006;13 Suppl 1:56–61.PubMed Hegarty NJ, Kaouk JH. Radical prostatectomy: a comparison of open, laparoscopic and robot-assisted laparoscopic techniques. Can J Urol. 2006;13 Suppl 1:56–61.PubMed
41.
Zurück zum Zitat Patel VR, Thaly R, Shah K. Robotic radical prostatectomy: outcomes of 500 cases. BJU Int. 2007;99(5):1109–12.PubMedCrossRef Patel VR, Thaly R, Shah K. Robotic radical prostatectomy: outcomes of 500 cases. BJU Int. 2007;99(5):1109–12.PubMedCrossRef
42.
Zurück zum Zitat Guillonneau B, Vallancien G. Laparoscopic radical prostatectomy: the Montsouris technique. J Urol. 2000;163(6):1643–9.PubMedCrossRef Guillonneau B, Vallancien G. Laparoscopic radical prostatectomy: the Montsouris technique. J Urol. 2000;163(6):1643–9.PubMedCrossRef
43.
Zurück zum Zitat Menon M, Shrivastava A, Kaul S, et al. Vattikuti Institute prostatectomy: contemporary technique and analysis of results. Eur Urol. 2007;51(3):648–57.PubMedCrossRef Menon M, Shrivastava A, Kaul S, et al. Vattikuti Institute prostatectomy: contemporary technique and analysis of results. Eur Urol. 2007;51(3):648–57.PubMedCrossRef
Metadaten
Titel
Current Status of Salvage Robot-Assisted Laparoscopic Prostatectomy for Radiorecurrent Prostate Cancer
verfasst von
Bernardo Rocco
Gabriele Cozzi
Matteo Giulio Spinelli
Angelica Grasso
Daniela Varisco
Rafael F. Coelho
Vipul R. Patel
Publikationsdatum
01.06.2012
Verlag
Current Science Inc.
Erschienen in
Current Urology Reports / Ausgabe 3/2012
Print ISSN: 1527-2737
Elektronische ISSN: 1534-6285
DOI
https://doi.org/10.1007/s11934-012-0245-1

Weitere Artikel der Ausgabe 3/2012

Current Urology Reports 3/2012 Zur Ausgabe

Endourology (V Bird, Section Editor)

Stone Management for the Patient on Anticoagulation

Female urology (A Gousse, Section Editor)

Anterior Pelvic Organ Prolapse Repair Using Synthetic Mesh

Update Urologie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.