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Erschienen in:

26.05.2016

Current views on anthracycline cardiotoxicity

verfasst von: Donato Mele, Marianna Nardozza, Paolo Spallarossa, Antonio Frassoldati, Carlo G. Tocchetti, Christian Cadeddu, Rosalinda Madonna, Michele Malagù, Roberto Ferrari, Giuseppe Mercuro

Erschienen in: Heart Failure Reviews | Ausgabe 5/2016

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Abstract

Anthracyclines are well established and effective anticancer agents used to treat a variety of adult and pediatric cancers. Unfortunately, these drugs are also among the commonest chemotherapeutic agents that have been recognized to cause cardiotoxicity. In the last years, several experimental and clinical investigations provided new information and perspectives on anthracycline-related cardiotoxicity. In particular, molecular mechanisms of cardiotoxicity have been better elucidated, early diagnosis has improved through the use of advanced noninvasive cardiac imaging techniques, and emerging data indicate a genetic predisposition to develop anthracycline-related cardiotoxicity. In this article, we review established and new knowledge about anthracycline cardiotoxicity, with special focus on recent advances in cardiotoxicity diagnosis and genetic profiling.

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Titel: Current views on anthracycline cardiotoxicity
verfasst von: Donato Mele
Marianna Nardozza
Paolo Spallarossa
Antonio Frassoldati
Carlo G. Tocchetti
Christian Cadeddu
Rosalinda Madonna
Michele Malagù
Roberto Ferrari
Giuseppe Mercuro
Publikationsdatum: 26.05.2016
Verlag: Springer US
Erschienen in: Heart Failure Reviews / Ausgabe 5/2016
Print ISSN: 1382-4147
Elektronische ISSN: 1573-7322
DOI: https://doi.org/10.1007/s10741-016-9564-5

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Live-Webinar: Aktuelle Leitlinien bei Herz-Kreislauf-Erkrankungen

Springer Medizin

Current views on anthracycline cardiotoxicity

Abstract

Neu im Fachgebiet Kardiologie

Wie erfolgreich ist eine Re-Ablation nach Rezidiv?

Europäische Ernährungsgewohnheiten: Das sind die häufigsten Fehler

Parodontalbehandlung verbessert Prognose bei Katheterablation

Antihypertensiva schützen auch alte Menschen noch vor Demenz

Update Kardiologie

Live-Webinar: Aktuelle Leitlinien bei Herz-Kreislauf-Erkrankungen

Springer Medizin

Abstract

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Weitere Artikel der Ausgabe 5/2016

Mitochondrial pathways to cardiac recovery: TFAM

Mitochondrial DNA repair: a novel therapeutic target for heart failure

Pathophysiological mechanism and therapeutic role of S100 proteins in cardiac failure: a systematic review

A review on B-type natriuretic peptide monitoring: assays and biosensors

Targeting BNIP3 in inflammation-mediated heart failure: a novel concept in heart failure therapy

Mitochondrial sirtuins in the heart

Neu im Fachgebiet Kardiologie

Wie erfolgreich ist eine Re-Ablation nach Rezidiv?

Europäische Ernährungsgewohnheiten: Das sind die häufigsten Fehler

Parodontalbehandlung verbessert Prognose bei Katheterablation

Antihypertensiva schützen auch alte Menschen noch vor Demenz

Update Kardiologie