Erschienen in:
01.01.2012 | Original Article
Cytomorphological changes in buccal mucosa of patients treated with low-level 1,064-nm laser radiation
verfasst von:
Ufuk Sezer, Mutan Hamdi Aras, Ali Murat Aktan, Beyhan Cengiz, Nadide Özkul, Sinan Ay
Erschienen in:
Lasers in Medical Science
|
Ausgabe 1/2012
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Abstract
The aim of this study was to examine the cytomorphological changes occurring in the buccal mucosa in patients treated with low-level 1,064-nm laser radiation. Seventeen individuals (12 males, five females) 18–24 years of age were included in the study. Low-level 1,064-nm laser radiation was applied to the right buccal mucosa near the premolar region; this therapy was repeated for 10 days. Buccal epithelial cells were collected from the right and left premolar regions of the individuals with a brush before and after therapy. The specimens collected from the left side were measured cytomorphometrically and used for the control group. Student’s t test was used for statistical comparison of the values of the buccal epithelial cells collected from individuals; a p value < 0.05 was considered statistically significant. None of the patients showed any adverse reactions to the low-level 1,064-nm laser radiation therapy during application. There was no cytogenetic damage to the therapied or non-therapied regions in the buccal mucosa cells, as determined cytomorphologically. The results suggest that low-level 1,064-nm laser radiation therapy has no genotoxic potential. Within the limitations of this study, it can be concluded that low-level 1,064-nm laser radiation therapy may be used safely in dental treatments.