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Erschienen in: Indian Journal of Surgery 6/2021

16.01.2021 | Review Article

Amebic Colitis and the Surgeon

verfasst von: Mohammad Ibrarullah, Wani Hamza Bruno

Erschienen in: Indian Journal of Surgery | Ausgabe 6/2021

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Abstract

Amoebiasis is a disease of public health importance in developing countries like India. The disease is caused by Entamoeba histolytica. In India, the recorded incidence including the non-pathogenic Entamoeba dispar is 2–55%. Asymptomatic colonization by Entamoeba histolytica accounts for nearly 90% of all cases of intestinal amebiasis. Acute amebic colitis is the commonest manifestation reported in 95% of patients with symptomatic amebiasis. Fulminant necrotizing colitis (FNC) accounts for 0.5–11% of patients with symptomatic amebiasis. Examination of at least three stool samples on three separate days is required to achieve a detection rate of 85–95%. The sensitivity and specificity of monoclonal antibody–based ELISA for detection of E. histolytica-specific antigen in stool specimen is 85% and 90% respectively. Treatment of invasive amebiasis should be started with metronidazole. Current recommendations favour resection ranging from segmental excision to subtotal or total colectomy depending on the extent of colonic involvement. Simple closure of perforation is deemed to fail and not recommended.
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Metadaten
Titel
Amebic Colitis and the Surgeon
verfasst von
Mohammad Ibrarullah
Wani Hamza Bruno
Publikationsdatum
16.01.2021
Verlag
Springer India
Erschienen in
Indian Journal of Surgery / Ausgabe 6/2021
Print ISSN: 0972-2068
Elektronische ISSN: 0973-9793
DOI
https://doi.org/10.1007/s12262-021-02723-3

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