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01.12.2023 | Original Article

Association between exercise and risk of fractures in new-onset type 2 diabetes: a retrospective cohort study

verfasst von: Seung Eun Lee, Juhwan Yoo, Bong-Seong Kim, Kyoung-Ah Kim, Kyungdo Han, Han Seok Choi

Erschienen in: Archives of Osteoporosis | Ausgabe 1/2023

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Abstract

Summary

In this population-based retrospective cohort study, exercising before and after the diagnosis of type 2 diabetes was significantly associated with lower risk of fractures. This result suggested that exercising might be effective in reducing fracture risk.

Purpose

Patients with diabetes have a significantly higher risk of fractures. We aimed to investigate the association between exercise and fracture risk in new-onset type 2 diabetes.

Methods

This retrospective cohort study using the Korean National Health Insurance Service database included 170,148 patients with new-onset type 2 diabetes who underwent two cycles of health checkup between 2009–2012 and 2011–2014. The patients were classified into four groups (non-exercising, newly exercising, previously exercising, and continuously exercising) and followed up until the date of fracture, death, or December 31, 2018. Hip fractures, vertebral fractures, and any fractures were defined using diagnostic codes.

Results

The proportions of non-exercising, newly exercising, previously exercising, and continuously exercising patients were 65.1%, 15.7%, 10.9%, and 8.3%, respectively. Continuously exercising patients showed the lowest risk for fractures, followed by newly exercising patients using the non-exercising group as a reference. The adjusted hazard ratios (95% confidence intervals) for hip fracture, vertebral fracture, and any fracture were 0.69 (0.50–0.94), 0.73 (0.63–0.84), and 0.90 (0.83–0.97), respectively, in the continuously exercising group and 0.76 (0.61–0.95), 0.85 (0.76–0.94), and 0.93 (0.88–0.98) in the newly exercising group. The risk was lower in patients who lost less than 5% of their body weight than in those who lost 5% or more.

Conclusion

Exercising was associated with lower risk of fractures in newly diagnosed diabetes. However, exercise accompanied by excessive weight loss may not have a significant association with a lower risk of fractures.
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Metadaten
Titel
Association between exercise and risk of fractures in new-onset type 2 diabetes: a retrospective cohort study
verfasst von
Seung Eun Lee
Juhwan Yoo
Bong-Seong Kim
Kyoung-Ah Kim
Kyungdo Han
Han Seok Choi
Publikationsdatum
01.12.2023
Verlag
Springer London
Erschienen in
Archives of Osteoporosis / Ausgabe 1/2023
Print ISSN: 1862-3522
Elektronische ISSN: 1862-3514
DOI
https://doi.org/10.1007/s11657-023-01240-y

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