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Erschienen in: Clinical Autonomic Research 4/2023

28.04.2023 | Research Article

Augmented ocular vestibular-evoked myogenic potentials in postural orthostatic tachycardia syndrome

verfasst von: Keun-Tae Kim, Sun-Uk Lee, Jung-Bin Kim, Jeong-Yoon Choi, Byung-Jo Kim, Ji-Soo Kim

Erschienen in: Clinical Autonomic Research | Ausgabe 4/2023

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Abstract

Purpose

To delineate the association between otolith function and changes in mean orthostatic blood pressure (BP) and heart rate (HR) in patients with postural orthostatic tachycardia syndrome (POTS).

Methods

Forty-nine patients with POTS were prospectively recruited. We analyzed the results of ocular vestibular-evoked myogenic potentials (oVEMPs) and cervical vestibular-evoked myogenic potentials (cVEMPs), as well as head-up tilt table tests using a Finometer. The oVEMP and cVEMP responses were obtained using tapping stimuli and 110 dB tone-burst sounds, respectively. We measured maximal changes in 5-s averaged systolic BP (SBP), diastolic BP (DBP), and heart rate (HR) within 15 s and during 10 min after tilting. We compared the results with those of 20 age- and sex-matched healthy participants.

Results

The n1–p1 amplitude of oVEMPs was larger in patients with POTS than in healthy participants (p = 0.001), whereas the n1 latency (p = 0.280) and interaural difference (p = 0.199) did not differ between the two. The n1–p1 amplitude was a positive predictor for POTS (odds ratio 1.07, 95% confidence interval 1.01–1.13, p = 0.025). Body weight (p = 0.007) and n1–p1 amplitude of oVEMP (p = 0.019) were positive predictors for ΔSBP15s in POTS, whereas aging was a negative predictor (p = 0.005). These findings were not observed in healthy participants.

Conclusions

Augmented utricular inputs may be associated with a relative predominance of sympathetic over vagal control of BP and HR, especially for an early response during orthostasis in patients with POTS. Overt sympathoexcitation due to exaggerated utricular input and lack of readaptation may be associated with the pathomechanism of POTS.
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Literatur
1.
Zurück zum Zitat Bogle JM, Benarroch E, Sandroni P (2022) Vestibular-autonomic interactions: beyond orthostatic dizziness. Curr Opin Neurol 35:126–134 PubMedCrossRef Bogle JM, Benarroch E, Sandroni P (2022) Vestibular-autonomic interactions: beyond orthostatic dizziness. Curr Opin Neurol 35:126–134 PubMedCrossRef
3.
Zurück zum Zitat Jian B, Acernese A, Lorenzo J, Card J, Yates B (2005) Afferent pathways to the region of the vestibular nuclei that participates in cardiovascular and respiratory control. Brain Res 1044:241–250 PubMedCrossRef Jian B, Acernese A, Lorenzo J, Card J, Yates B (2005) Afferent pathways to the region of the vestibular nuclei that participates in cardiovascular and respiratory control. Brain Res 1044:241–250 PubMedCrossRef
4.
Zurück zum Zitat Uchino Y, Kudo N, Tsuda K, Iwamura Y (1970) Vestibular inhibition of sympathetic nerve activities. Brain Res 22:195–206 PubMedCrossRef Uchino Y, Kudo N, Tsuda K, Iwamura Y (1970) Vestibular inhibition of sympathetic nerve activities. Brain Res 22:195–206 PubMedCrossRef
5.
Zurück zum Zitat Thijs RD, Brignole M, Falup-Pecurariu C, Fanciulli A, Freeman R, Guaraldi P, Jordan J, Habek M, Hilz M, Pavy-LeTraon A (2021) Recommendations for tilt table testing and other provocative cardiovascular autonomic tests in conditions that may cause transient loss of consciousness: consensus statement of the European federation of autonomic societies (EFAS) endorsed by the American autonomic society (AAS) and the European academy of neurology (EAN). Aut Neurosci 233:102792 CrossRef Thijs RD, Brignole M, Falup-Pecurariu C, Fanciulli A, Freeman R, Guaraldi P, Jordan J, Habek M, Hilz M, Pavy-LeTraon A (2021) Recommendations for tilt table testing and other provocative cardiovascular autonomic tests in conditions that may cause transient loss of consciousness: consensus statement of the European federation of autonomic societies (EFAS) endorsed by the American autonomic society (AAS) and the European academy of neurology (EAN). Aut Neurosci 233:102792 CrossRef
6.
Zurück zum Zitat Freeman R, Wieling W, Axelrod FB, Benditt DG, Benarroch E, Biaggioni I, Cheshire WP, Chelimsky T, Cortelli P, Gibbons CH (2011) Consensus statement on the definition of orthostatic hypotension, neurally mediated syncope and the postural tachycardia syndrome. Clin Aut Res 21:69–72 CrossRef Freeman R, Wieling W, Axelrod FB, Benditt DG, Benarroch E, Biaggioni I, Cheshire WP, Chelimsky T, Cortelli P, Gibbons CH (2011) Consensus statement on the definition of orthostatic hypotension, neurally mediated syncope and the postural tachycardia syndrome. Clin Aut Res 21:69–72 CrossRef
7.
Zurück zum Zitat Schondorf R, Benoit J, Wein T, Phaneuf D (1999) Orthostatic intolerance in the chronic fatigue syndrome. J Auton Nerve Syst 5(2–3):192–201 CrossRef Schondorf R, Benoit J, Wein T, Phaneuf D (1999) Orthostatic intolerance in the chronic fatigue syndrome. J Auton Nerve Syst 5(2–3):192–201 CrossRef
8.
Zurück zum Zitat Low PA, Sandroni P, Joyner M, Shen WK (2009) Postural tachycardia syndrome (POTS). J Cardiovasc Eletrophysiol 20:352–358 CrossRef Low PA, Sandroni P, Joyner M, Shen WK (2009) Postural tachycardia syndrome (POTS). J Cardiovasc Eletrophysiol 20:352–358 CrossRef
9.
Zurück zum Zitat Low PA, Opfer-Gehrking TL, Textor SC, Schondorf R, Suarez GA, Fealey RD, Camilleri M (1994) Comparison of the postural tachycardia syndrome (POTS) with orthostatic hypotension due to autonomic failure. J Auton Nerve Syst 50:181–188 CrossRef Low PA, Opfer-Gehrking TL, Textor SC, Schondorf R, Suarez GA, Fealey RD, Camilleri M (1994) Comparison of the postural tachycardia syndrome (POTS) with orthostatic hypotension due to autonomic failure. J Auton Nerve Syst 50:181–188 CrossRef
10.
11.
Zurück zum Zitat Kwon E, Lee JY, Kim HJ, Choi JY, Kim JS (2021) Can dyssynergia of vestibulosympathetic and baroreflexes cause vestibular syncope? The hypothesis based on the velocity-storage function. Cerebellum 21:244–252 PubMedCrossRef Kwon E, Lee JY, Kim HJ, Choi JY, Kim JS (2021) Can dyssynergia of vestibulosympathetic and baroreflexes cause vestibular syncope? The hypothesis based on the velocity-storage function. Cerebellum 21:244–252 PubMedCrossRef
12.
Zurück zum Zitat Kim JG, Lee JH, Lee SU, Choi JY, Kim BJ, Kim JS (2022) Utricular dysfunction in patients with orthostatic hypotension. Clin Aut Res 32:431–444 CrossRef Kim JG, Lee JH, Lee SU, Choi JY, Kim BJ, Kim JS (2022) Utricular dysfunction in patients with orthostatic hypotension. Clin Aut Res 32:431–444 CrossRef
13.
Zurück zum Zitat Yates BJ, Bronstein AM (2005) The effects of vestibular system lesions on autonomic regulation: observations, mechanisms, and clinical implications. J Vestib Res 15:119–129 PubMedCrossRef Yates BJ, Bronstein AM (2005) The effects of vestibular system lesions on autonomic regulation: observations, mechanisms, and clinical implications. J Vestib Res 15:119–129 PubMedCrossRef
14.
Zurück zum Zitat Heidenreich KD, Weisend S, Fouad-Tarazi FM, White JA (2009) The incidence of coexistent autonomic and vestibular dysfunction in patients with postural dizziness. Am J Otolaryngol 30:225–229 PubMedCrossRef Heidenreich KD, Weisend S, Fouad-Tarazi FM, White JA (2009) The incidence of coexistent autonomic and vestibular dysfunction in patients with postural dizziness. Am J Otolaryngol 30:225–229 PubMedCrossRef
15.
Zurück zum Zitat Goodman B, Dhawan P, Bogle J, Barrs D, Hoffman-Snyder C (2015) Vestibular symptoms are common in postural tachycardia syndrome (PoTS) (P1.281). Neurology 84:P1.281 Goodman B, Dhawan P, Bogle J, Barrs D, Hoffman-Snyder C (2015) Vestibular symptoms are common in postural tachycardia syndrome (PoTS) (P1.281). Neurology 84:P1.281
16.
Zurück zum Zitat Kim HA, Yi HA, Lee H (2015) Orthostatic hypotension in acute vestibular neuritis. J Neurol Sci 358:479–480 PubMedCrossRef Kim HA, Yi HA, Lee H (2015) Orthostatic hypotension in acute vestibular neuritis. J Neurol Sci 358:479–480 PubMedCrossRef
17.
Zurück zum Zitat Whitman GT, Yates BJ (2015) Orthostatic intolerance in acute vestibular neuritis. Mayo Clin Proc 90:308–309 PubMedCrossRef Whitman GT, Yates BJ (2015) Orthostatic intolerance in acute vestibular neuritis. Mayo Clin Proc 90:308–309 PubMedCrossRef
18.
Zurück zum Zitat Olshansky B, Cannom D, Fedorowski A, Stewart J, Gibbons C, Sutton R, Shen W-K, Muldowney J, Chung TH, Feigofsky S (2020) Postural orthostatic tachycardia syndrome (POTS): a critical assessment. Prog Cardiovasc Dis 63:263–270 PubMedPubMedCentralCrossRef Olshansky B, Cannom D, Fedorowski A, Stewart J, Gibbons C, Sutton R, Shen W-K, Muldowney J, Chung TH, Feigofsky S (2020) Postural orthostatic tachycardia syndrome (POTS): a critical assessment. Prog Cardiovasc Dis 63:263–270 PubMedPubMedCentralCrossRef
19.
Zurück zum Zitat Seok HY, Kim YH, Kim H, Kim BJ (2018) Patterns of orthostatic blood pressure changes in patients with orthostatic hypotension. J Clin Neurol 14:283–290 PubMedPubMedCentralCrossRef Seok HY, Kim YH, Kim H, Kim BJ (2018) Patterns of orthostatic blood pressure changes in patients with orthostatic hypotension. J Clin Neurol 14:283–290 PubMedPubMedCentralCrossRef
20.
Zurück zum Zitat Kim JB, Kim BJ, Koh SB, Park KW (2014) Autonomic dysfunction according to disease progression in Parkinson’s disease. Parkinsonism Relat Disord 20:303–307 PubMedCrossRef Kim JB, Kim BJ, Koh SB, Park KW (2014) Autonomic dysfunction according to disease progression in Parkinson’s disease. Parkinsonism Relat Disord 20:303–307 PubMedCrossRef
21.
Zurück zum Zitat Kim JB, Kim H, Sung JH, Baek SH, Kim BJ (2020) Heart-rate-based machine-learning algorithms for screening orthostatic hypotension. J Clin Neurol 16:448–454 PubMedPubMedCentralCrossRef Kim JB, Kim H, Sung JH, Baek SH, Kim BJ (2020) Heart-rate-based machine-learning algorithms for screening orthostatic hypotension. J Clin Neurol 16:448–454 PubMedPubMedCentralCrossRef
22.
Zurück zum Zitat Romero-Ortuno R, Cogan L, Fan CW, Kenny RA (2010) Intolerance to initial orthostasis relates to systolic BP changes in elders. Clin Auton Res 20:39–45 PubMedCrossRef Romero-Ortuno R, Cogan L, Fan CW, Kenny RA (2010) Intolerance to initial orthostasis relates to systolic BP changes in elders. Clin Auton Res 20:39–45 PubMedCrossRef
23.
Zurück zum Zitat van der Velde N, van den Meiracker AH, Stricker BHC, van der Cammen TJ (2007) Measuring orthostatic hypotension with the Finometer device: is a blood pressure drop of one heartbeat clinically relevant? Blood Press Monit 12:167–171 PubMedCrossRef van der Velde N, van den Meiracker AH, Stricker BHC, van der Cammen TJ (2007) Measuring orthostatic hypotension with the Finometer device: is a blood pressure drop of one heartbeat clinically relevant? Blood Press Monit 12:167–171 PubMedCrossRef
24.
Zurück zum Zitat Kim HJ, Lee JH, Kim JS (2014) Ocular vestibular evoked myogenic potentials to head tap and cervical vestibular evoked myogenic potentials to air-conducted sounds in isolated internuclear ophthalmoplegia. Clin Neurophysiol 125:1042–1047 PubMedCrossRef Kim HJ, Lee JH, Kim JS (2014) Ocular vestibular evoked myogenic potentials to head tap and cervical vestibular evoked myogenic potentials to air-conducted sounds in isolated internuclear ophthalmoplegia. Clin Neurophysiol 125:1042–1047 PubMedCrossRef
25.
Zurück zum Zitat Lee SU, Kim HJ, Choi JY, Koo JW, Kim JS (2017) Abnormal cervical vestibular-evoked myogenic potentials predict evolution of isolated recurrent vertigo into Meniere’s disease. Front Neurol 8:463 PubMedPubMedCentralCrossRef Lee SU, Kim HJ, Choi JY, Koo JW, Kim JS (2017) Abnormal cervical vestibular-evoked myogenic potentials predict evolution of isolated recurrent vertigo into Meniere’s disease. Front Neurol 8:463 PubMedPubMedCentralCrossRef
28.
Zurück zum Zitat Streeten DH (1987) Orthostatic disorders of the circulation: mechanisms, manifestations, and treatment, 1st edn. Springer, Berlin CrossRef Streeten DH (1987) Orthostatic disorders of the circulation: mechanisms, manifestations, and treatment, 1st edn. Springer, Berlin CrossRef
29.
Zurück zum Zitat Schondorf R, Low PA (1992) Gender related differences in the cardiovascular responses to upright tilt in normal subjects. Clin Aut Res 2:183–187 CrossRef Schondorf R, Low PA (1992) Gender related differences in the cardiovascular responses to upright tilt in normal subjects. Clin Aut Res 2:183–187 CrossRef
30.
Zurück zum Zitat Novak V, Novak P, Opfer-Gehrking TL, Low PA (1996) Postural tachycardia syndrome: time frequency mapping. J Auton Nerve Syst 61:313–320 CrossRef Novak V, Novak P, Opfer-Gehrking TL, Low PA (1996) Postural tachycardia syndrome: time frequency mapping. J Auton Nerve Syst 61:313–320 CrossRef
32.
Zurück zum Zitat Li J, Zhang Q, Liao Y, Zhang C, Hao H, Du J (2015) The value of acetylcholine receptor antibody in children with postural tachycardia syndrome. Pediatr Cardiol 36:165–170 PubMedCrossRef Li J, Zhang Q, Liao Y, Zhang C, Hao H, Du J (2015) The value of acetylcholine receptor antibody in children with postural tachycardia syndrome. Pediatr Cardiol 36:165–170 PubMedCrossRef
33.
Zurück zum Zitat Gunning WT III, Kvale H, Kramer PM, Karabin BL, Grubb BP (2019) Postural orthostatic tachycardia syndrome is associated with elevated G-protein coupled receptor autoantibodies. J Am Heart Assoc 8:e013602 PubMedPubMedCentralCrossRef Gunning WT III, Kvale H, Kramer PM, Karabin BL, Grubb BP (2019) Postural orthostatic tachycardia syndrome is associated with elevated G-protein coupled receptor autoantibodies. J Am Heart Assoc 8:e013602 PubMedPubMedCentralCrossRef
34.
Zurück zum Zitat Li H, Yu X, Liles C, Khan M, Vanderlinde-Wood M, Galloway A, Zillner C, Benbrook A, Reim S, Collier D (2014) Autoimmune basis for postural tachycardia syndrome. J Am Heart Assoc 3:e000755 PubMedPubMedCentralCrossRef Li H, Yu X, Liles C, Khan M, Vanderlinde-Wood M, Galloway A, Zillner C, Benbrook A, Reim S, Collier D (2014) Autoimmune basis for postural tachycardia syndrome. J Am Heart Assoc 3:e000755 PubMedPubMedCentralCrossRef
35.
Zurück zum Zitat Raj SR, Biaggioni I, Yamhure PC, Black BK, Paranjape SY, Byrne DW, Robertson D (2005) Renin-aldosterone paradox and perturbed blood volume regulation underlying postural tachycardia syndrome. Circulation 111:1574–1582 PubMedCrossRef Raj SR, Biaggioni I, Yamhure PC, Black BK, Paranjape SY, Byrne DW, Robertson D (2005) Renin-aldosterone paradox and perturbed blood volume regulation underlying postural tachycardia syndrome. Circulation 111:1574–1582 PubMedCrossRef
36.
Zurück zum Zitat Muenter Swift N, Charkoudian N, Dotson RM, Suarez GA, Low PA (2005) Baroreflex control of muscle sympathetic nerve activity in postural orthostatic tachycardia syndrome. Am J Physiol Heart Circ Physiol 289:H1226–H1233 PubMedCrossRef Muenter Swift N, Charkoudian N, Dotson RM, Suarez GA, Low PA (2005) Baroreflex control of muscle sympathetic nerve activity in postural orthostatic tachycardia syndrome. Am J Physiol Heart Circ Physiol 289:H1226–H1233 PubMedCrossRef
37.
Zurück zum Zitat Blitshteyn S (2022) Is postural orthostatic tachycardia syndrome (POTS) a central nervous system disorder? J Neurol 269:725–732 PubMedCrossRef Blitshteyn S (2022) Is postural orthostatic tachycardia syndrome (POTS) a central nervous system disorder? J Neurol 269:725–732 PubMedCrossRef
38.
Zurück zum Zitat Wagoner AL, Olson JD, Westwood BM, Fortunato JE, Diz DI, Shaltout HA (2019) Children with orthostatic intolerance exhibit elevated markers of inflammation in the dorsal medulla. Am J Physiol Heart Circ Physiol 317:H323–H329 PubMedCrossRef Wagoner AL, Olson JD, Westwood BM, Fortunato JE, Diz DI, Shaltout HA (2019) Children with orthostatic intolerance exhibit elevated markers of inflammation in the dorsal medulla. Am J Physiol Heart Circ Physiol 317:H323–H329 PubMedCrossRef
40.
Zurück zum Zitat Kim P, During E, Miglis M (2018) A case of narcolepsy type 2 and postural tachycardia syndrome secondary to lesions of the thalamus and amygdala. J Clin Sleep Med 14:479–481 PubMedPubMedCentralCrossRef Kim P, During E, Miglis M (2018) A case of narcolepsy type 2 and postural tachycardia syndrome secondary to lesions of the thalamus and amygdala. J Clin Sleep Med 14:479–481 PubMedPubMedCentralCrossRef
41.
Zurück zum Zitat Critchley HD, Nagai Y, Gray MA, Mathias CJ (2011) Dissecting axes of autonomic control in humans: insights from neuroimaging. Aut Neurosci 161:34–42 CrossRef Critchley HD, Nagai Y, Gray MA, Mathias CJ (2011) Dissecting axes of autonomic control in humans: insights from neuroimaging. Aut Neurosci 161:34–42 CrossRef
42.
Zurück zum Zitat Holstein GR, Friedrich VL Jr, Kang T, Kukielka E, Martinelli GP (2011) Direct projections from the caudal vestibular nuclei to the ventrolateral medulla in the rat. Neuroscience 175:104–117 PubMedCrossRef Holstein GR, Friedrich VL Jr, Kang T, Kukielka E, Martinelli GP (2011) Direct projections from the caudal vestibular nuclei to the ventrolateral medulla in the rat. Neuroscience 175:104–117 PubMedCrossRef
43.
Zurück zum Zitat Holstein GR, Friedrich VL Jr, Martinelli GP (2014) Projection neurons of the vestibulo-sympathetic reflex pathway. J Comp Neurol 522:2053–2074 PubMedPubMedCentralCrossRef Holstein GR, Friedrich VL Jr, Martinelli GP (2014) Projection neurons of the vestibulo-sympathetic reflex pathway. J Comp Neurol 522:2053–2074 PubMedPubMedCentralCrossRef
44.
Zurück zum Zitat Nagai M, Scheper V, Lenarz T, Förster CY (2021) The insular cortex as a vestibular area in relation to autonomic function. Clin Aut Res 31:179–185 CrossRef Nagai M, Scheper V, Lenarz T, Förster CY (2021) The insular cortex as a vestibular area in relation to autonomic function. Clin Aut Res 31:179–185 CrossRef
46.
47.
Zurück zum Zitat Mori RL, Cotter LA, Arendt HE, Olsheski CJ, Yates BJ (2005) Effects of bilateral vestibular nucleus lesions on cardiovascular regulation in conscious cats. J Appl Physiol 98:526–533 PubMedCrossRef Mori RL, Cotter LA, Arendt HE, Olsheski CJ, Yates BJ (2005) Effects of bilateral vestibular nucleus lesions on cardiovascular regulation in conscious cats. J Appl Physiol 98:526–533 PubMedCrossRef
48.
Zurück zum Zitat Yates BJ, Miller A (1994) Properties of sympathetic reflexes elicited by natural vestibular stimulation: implications for cardiovascular control. J Neurophysiol 71:2087–2092 PubMedCrossRef Yates BJ, Miller A (1994) Properties of sympathetic reflexes elicited by natural vestibular stimulation: implications for cardiovascular control. J Neurophysiol 71:2087–2092 PubMedCrossRef
49.
Zurück zum Zitat Benarroch EE (2012) Postural tachycardia syndrome: a heterogeneous and multifactorial disorder. Mayo Clin Proceed 87:1214–1225 CrossRef Benarroch EE (2012) Postural tachycardia syndrome: a heterogeneous and multifactorial disorder. Mayo Clin Proceed 87:1214–1225 CrossRef
50.
Zurück zum Zitat Watenpaugh DE, Cothron AV, Wasmund SL, Wasmund WL, Carter R III, Muenter NK, Smith ML (2002) Do vestibular otolith organs participate in human orthostatic blood pressure control? Aut Neurosci 100:77–83 CrossRef Watenpaugh DE, Cothron AV, Wasmund SL, Wasmund WL, Carter R III, Muenter NK, Smith ML (2002) Do vestibular otolith organs participate in human orthostatic blood pressure control? Aut Neurosci 100:77–83 CrossRef
51.
Zurück zum Zitat Kaufmann H, Biaggioni I, Voustianiouk A, Diedrich A, Costa F, Clarke R, Gizzi M, Raphan T, Cohen B (2002) Vestibular control of sympathetic activity. Exp Brain Res 143:463–469 PubMedCrossRef Kaufmann H, Biaggioni I, Voustianiouk A, Diedrich A, Costa F, Clarke R, Gizzi M, Raphan T, Cohen B (2002) Vestibular control of sympathetic activity. Exp Brain Res 143:463–469 PubMedCrossRef
52.
Zurück zum Zitat Li C, Layman AJ, Carey JP, Agrawal Y (2015) Epidemiology of vestibular evoked myogenic potentials: data from the Baltimore longitudinal study of aging. Clin Neurophysiol 126:2207–2015 PubMedPubMedCentralCrossRef Li C, Layman AJ, Carey JP, Agrawal Y (2015) Epidemiology of vestibular evoked myogenic potentials: data from the Baltimore longitudinal study of aging. Clin Neurophysiol 126:2207–2015 PubMedPubMedCentralCrossRef
53.
Zurück zum Zitat Naranjo EN, Cleworth TW, Allum J, Inglis JT, Lea J, Westerberg BD, Carpenter MG (2016) Vestibulo-spinal and vestibulo-ocular reflexes are modulated when standing with increased postural threat. J Neurophysiol 115:833–842 PubMedCrossRef Naranjo EN, Cleworth TW, Allum J, Inglis JT, Lea J, Westerberg BD, Carpenter MG (2016) Vestibulo-spinal and vestibulo-ocular reflexes are modulated when standing with increased postural threat. J Neurophysiol 115:833–842 PubMedCrossRef
54.
Zurück zum Zitat Tseng CL, Chou CH, Young YH (2010) Aging effect on the ocular vestibular-evoked myogenic potentials. Otol Neurotol 31:959–963 PubMedCrossRef Tseng CL, Chou CH, Young YH (2010) Aging effect on the ocular vestibular-evoked myogenic potentials. Otol Neurotol 31:959–963 PubMedCrossRef
55.
Zurück zum Zitat Makowiec KF, Piker EG, Jacobson GP, Ramadan NM, Roberts RA (2018) Ocular and cervical vestibular evoked myogenic potentials in patients with vestibular migraine. Otol Neurotol 39:e561–e567 PubMedCrossRef Makowiec KF, Piker EG, Jacobson GP, Ramadan NM, Roberts RA (2018) Ocular and cervical vestibular evoked myogenic potentials in patients with vestibular migraine. Otol Neurotol 39:e561–e567 PubMedCrossRef
56.
Zurück zum Zitat Zaleski A, Bogle J, Starling A, Zapala DA, Davis L, Wester M, Cevette M (2015) Vestibular evoked myogenic potentials in patients with vestibular migraine. Otol Neurotol 36:295–302 PubMedCrossRef Zaleski A, Bogle J, Starling A, Zapala DA, Davis L, Wester M, Cevette M (2015) Vestibular evoked myogenic potentials in patients with vestibular migraine. Otol Neurotol 36:295–302 PubMedCrossRef
57.
Zurück zum Zitat Zuniga MG, Janky KL, Schubert MC, Carey JP (2012) Can vestibular-evoked myogenic potentials help differentiate Ménière disease from vestibular migraine? Otolaryngol Head Neck Surg 146:788–796 PubMedPubMedCentralCrossRef Zuniga MG, Janky KL, Schubert MC, Carey JP (2012) Can vestibular-evoked myogenic potentials help differentiate Ménière disease from vestibular migraine? Otolaryngol Head Neck Surg 146:788–796 PubMedPubMedCentralCrossRef
58.
Zurück zum Zitat Dlugaiczyk J, Habs M, Dieterich M (2020) Vestibular evoked myogenic potentials in vestibular migraine and Menière’s disease: cVEMPs make the difference. J Neurol 267:169–180 PubMedPubMedCentralCrossRef Dlugaiczyk J, Habs M, Dieterich M (2020) Vestibular evoked myogenic potentials in vestibular migraine and Menière’s disease: cVEMPs make the difference. J Neurol 267:169–180 PubMedPubMedCentralCrossRef
59.
Zurück zum Zitat Taylor RL, Zagami AS, Gibson WP, Black DA, Watson SR, Halmagyi MG, Welgampola MS (2012) Vestibular evoked myogenic potentials to sound and vibration: characteristics in vestibular migraine that enable separation from Meniere’s disease. Cephalalgia 32:213–225 PubMedCrossRef Taylor RL, Zagami AS, Gibson WP, Black DA, Watson SR, Halmagyi MG, Welgampola MS (2012) Vestibular evoked myogenic potentials to sound and vibration: characteristics in vestibular migraine that enable separation from Meniere’s disease. Cephalalgia 32:213–225 PubMedCrossRef
60.
Zurück zum Zitat Schondorf R, Low PA (1993) Idiopathic postural orthostatic tachycardia syndrome: an attenuated form of acute pandysautonomia? Neurology 43:132–137 PubMedCrossRef Schondorf R, Low PA (1993) Idiopathic postural orthostatic tachycardia syndrome: an attenuated form of acute pandysautonomia? Neurology 43:132–137 PubMedCrossRef
61.
Zurück zum Zitat Thieben MJ, Sandroni P, Sletten DM, Benrud-Larson LM, Fealey RD, Vernino S, Low PA, Lennon VA, Shen W-K (2007) Postural orthostatic tachycardia syndrome: the Mayo clinic experience. Mayo Clin Proc 82:308–313 PubMedCrossRef Thieben MJ, Sandroni P, Sletten DM, Benrud-Larson LM, Fealey RD, Vernino S, Low PA, Lennon VA, Shen W-K (2007) Postural orthostatic tachycardia syndrome: the Mayo clinic experience. Mayo Clin Proc 82:308–313 PubMedCrossRef
62.
Zurück zum Zitat Mathias C, Mallipeddi R, Bleasdale-Barr K (1999) Symptoms associated with orthostatic hypotension in pure autonomic failure and multiple system atrophy. J Neurol 246:893–898 PubMedCrossRef Mathias C, Mallipeddi R, Bleasdale-Barr K (1999) Symptoms associated with orthostatic hypotension in pure autonomic failure and multiple system atrophy. J Neurol 246:893–898 PubMedCrossRef
63.
Zurück zum Zitat Fu Q, VanGundy TB, Galbreath MM, Shibata S, Jain M, Hastings JL, Bhella PS, Levine BD (2010) Cardiac origins of the postural orthostatic tachycardia syndrome. J Am Coll Cardiol 55:2858–2868 PubMedPubMedCentralCrossRef Fu Q, VanGundy TB, Galbreath MM, Shibata S, Jain M, Hastings JL, Bhella PS, Levine BD (2010) Cardiac origins of the postural orthostatic tachycardia syndrome. J Am Coll Cardiol 55:2858–2868 PubMedPubMedCentralCrossRef
64.
Zurück zum Zitat Pliego A, Vega R, Gómez R, Reyes-Lagos JJ, Soto E (2021) A transient decrease in heart rate with unilateral and bilateral galvanic vestibular stimulation in healthy humans. Eur J Neurosci 54:4670–4681 PubMedCrossRef Pliego A, Vega R, Gómez R, Reyes-Lagos JJ, Soto E (2021) A transient decrease in heart rate with unilateral and bilateral galvanic vestibular stimulation in healthy humans. Eur J Neurosci 54:4670–4681 PubMedCrossRef
65.
Zurück zum Zitat Cohen B, Martinelli GP, Ogorodnikov D, Xiang Y, Raphan T, Holstein GR, Yakushin SB (2011) Sinusoidal galvanic vestibular stimulation (sGVS) induces a vasovagal response in the rat. Exp Brain Res 210:45–55 PubMedPubMedCentralCrossRef Cohen B, Martinelli GP, Ogorodnikov D, Xiang Y, Raphan T, Holstein GR, Yakushin SB (2011) Sinusoidal galvanic vestibular stimulation (sGVS) induces a vasovagal response in the rat. Exp Brain Res 210:45–55 PubMedPubMedCentralCrossRef
66.
Zurück zum Zitat Cohen B, Martinelli GP, Xiang Y, Raphan T, Yakushin SB (2017) Vestibular activation habituates the vasovagal response in the rat. Front Neurol 8:83 PubMedPubMedCentralCrossRef Cohen B, Martinelli GP, Xiang Y, Raphan T, Yakushin SB (2017) Vestibular activation habituates the vasovagal response in the rat. Front Neurol 8:83 PubMedPubMedCentralCrossRef
68.
Zurück zum Zitat Yakushin SB, Martinelli GP, Raphan T, Xiang Y, Holstein GR, Cohen B (2014) Vasovagal oscillations and vasovagal responses produced by the vestibulo-sympathetic reflex in the rat. Front Neurol 5:37 PubMedPubMedCentralCrossRef Yakushin SB, Martinelli GP, Raphan T, Xiang Y, Holstein GR, Cohen B (2014) Vasovagal oscillations and vasovagal responses produced by the vestibulo-sympathetic reflex in the rat. Front Neurol 5:37 PubMedPubMedCentralCrossRef
Metadaten
Titel
Augmented ocular vestibular-evoked myogenic potentials in postural orthostatic tachycardia syndrome
verfasst von
Keun-Tae Kim
Sun-Uk Lee
Jung-Bin Kim
Jeong-Yoon Choi
Byung-Jo Kim
Ji-Soo Kim
Publikationsdatum
28.04.2023
Verlag
Springer Berlin Heidelberg
Erschienen in
Clinical Autonomic Research / Ausgabe 4/2023
Print ISSN: 0959-9851
Elektronische ISSN: 1619-1560
DOI
https://doi.org/10.1007/s10286-023-00943-z

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