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Erschienen in: Clinical Autonomic Research 2/2023

07.03.2023 | Letter to the Editor

Baroreflex-sympathoneural without baroreflex-cardiovagal failure in neurogenic orthostatic hypotension

verfasst von: David S. Goldstein, Samantha Dill, Patti Sullivan, Edward Grabov, Prashant Chittiboina

Erschienen in: Clinical Autonomic Research | Ausgabe 2/2023

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Abstract

We describe a patient with neurogenic orthostatic hypotension (nOH) after brainstem neurosurgery in whom baroreflex-cardiovagal function was normal despite baroreflex-sympathoneural failure. We also cite other conditions entailing differential alterations in the two efferent limbs of the baroreflex. Any condition involving nOH from selective loss of sympathetic noradrenergic innervation, interference with sympathetic pre-ganglionic transmission in the thoracolumbar spinal cord, sympathectomies, or attenuated intra-neuronal synthesis, storage, or release of norepinephrine would be expected to manifest with selective baroreflex-sympathoneural dysfunction. We advise caution in relying on indices of baroreflex-cardiovagal function for diagnosing nOH, since normal values for these indices do not exclude nOH.
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Metadaten
Titel
Baroreflex-sympathoneural without baroreflex-cardiovagal failure in neurogenic orthostatic hypotension
verfasst von
David S. Goldstein
Samantha Dill
Patti Sullivan
Edward Grabov
Prashant Chittiboina
Publikationsdatum
07.03.2023
Verlag
Springer Berlin Heidelberg
Erschienen in
Clinical Autonomic Research / Ausgabe 2/2023
Print ISSN: 0959-9851
Elektronische ISSN: 1619-1560
DOI
https://doi.org/10.1007/s10286-023-00935-z

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