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01.09.2013 | Leitthema

Bildgebung beim Prostatakarzinom

State of the Art

verfasst von: U.I. Attenberger, MD, S.O. Schoenberg, A. Weidner, M. Niyazi, L.K. Bittencourt, D. Buergy, M. Sertdemir, D. Hausmann

Erschienen in: Die Onkologie | Ausgabe 9/2013

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Zusammenfassung

Hintergrund

Im Rahmen der Magnetresonanztomographie (MRT) kann die Prostata mit dem besten Weichgewebskontrast und der höchsten räumlichen Auflösung aller bildgebenden Verfahren beurteilt werden. Gleichzeitig können zusätzlich zur rein anatomisch-morphologischen Information auch funktionelle Parameter, wie Gewebedurchblutung (Perfusion), -stoffwechsel (MR-Spektroskopie, MRS) und Zelldichte (diffusionsgewichtete Bildgebung, DWI) bestimmt werden.

Material und Methoden

Zahlreiche Studien belegen bereits den Stellenwert der MRT in der Lokalisation von Karzinomherden bei Patienten mit steigender Konzentration des prostataspezifischen Antigens (PSA) und stattgehabter Negativbiopsie. Insbesondere in der Drüsenperipherie, der häufigsten Manifestationsstelle eines PCa, erlaubt die kombinierte Analyse morphologischer und funktioneller Parameter, den PCa-Fokus von mit einer Prostatitis einhergehenden Veränderungen spezifisch zu differenzieren. Neben der Primärdiagnostik findet die MRT ihren wertvollen Einsatz auch in der präoperativen Beurteilung evtl. vorliegenden extrakapsulären Wachstums/Samenblasenbefalls und nach z. B. erfolgter Radiatio in der Rezidivsituation oder bei biochemischem Rezidiv nach radikaler Prostatektomie.

Schlussfolgerungen

Damit stellt die sog. multiparametrische (mMRT) ein sehr leistungsfähiges Verfahren für die Diagnose des PCa dar.
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Metadaten
Titel
Bildgebung beim Prostatakarzinom
State of the Art
verfasst von
U.I. Attenberger, MD
S.O. Schoenberg
A. Weidner
M. Niyazi
L.K. Bittencourt
D. Buergy
M. Sertdemir
D. Hausmann
Publikationsdatum
01.09.2013
Verlag
Springer Berlin Heidelberg
Erschienen in
Die Onkologie / Ausgabe 9/2013
Print ISSN: 2731-7226
Elektronische ISSN: 2731-7234
DOI
https://doi.org/10.1007/s00761-013-2484-2

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