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Erschienen in: European Journal of Applied Physiology 10/2022

19.07.2022 | Original Article

Central arterial stiffness, wave reflection, and heart rate variability following 4-week high-intensity resistance training intervention in young active women

verfasst von: Sarean Harmoni A. Gaynor-Metzinger, N. Travis Triplett, Marco Meucci, Kimberly S. Fasczewski, Damon H. Flinchum, Scott R. Collier

Erschienen in: European Journal of Applied Physiology | Ausgabe 10/2022

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Abstract

Purpose

Arterial stiffness, expedited wave reflection, and autonomic dysfunction are risk factors for cardiovascular disease, which is the leading cause of death in women in the United States. Evaluation of the effects of resistance training on these factors has been inconclusive, and even less is known about the effects of high-intensity resistance training (HIRT). This study evaluated the effects of a 4-week HIRT intervention on central arterial stiffness, wave reflection, and heart rate variability in young healthy and active women.

Methods

9 women were recruited and underwent a 4-week control period followed by the intervention. Measurements were recorded pre-control, post-control/pre-intervention, and post-intervention.

Results

There were no significant changes to central arterial stiffness, wave reflection, or heart rate variability. There was a significant increase in resting heart rate (bpm: 62 ± 7, 66 ± 10; p = 0.003) and a significant decrease in baroreceptor sensitivity (30 ± 7, 21 ± 7; p = 0.018) pre- to post-intervention. There was a significant decrease in total peripheral resistance pre- to post-intervention (1.076 ± 0.281, 0.916 ± 0.250; p = 0.002). Squat, bench press, and deadlift increased pre- to post-intervention (kg: 62 ± 11, 71 ± 9, p = 0.000; 37 ± 7, 40 ± 7, p = 0.002; 76 ± 19, 84 ± 19, p = 0.000).

Conclusion

4 weeks of HIRT can supplement a healthy lifestyle in women by increasing strength while decreasing peripheral resistance and preserving arterial pressures. Further evaluation is necessary to investigate the observed increase in resting heart rate and decrease in baroreceptor sensitivity and to determine long-term effects of this training.
Literatur
Zurück zum Zitat Abdel-Rahman AR, Merrill RH, Wooles WR (1994) Gender-related differences in the baroreceptor reflex control of heart rate in normotensive humans. J Appl Physiol 77(2):606–613CrossRef Abdel-Rahman AR, Merrill RH, Wooles WR (1994) Gender-related differences in the baroreceptor reflex control of heart rate in normotensive humans. J Appl Physiol 77(2):606–613CrossRef
Zurück zum Zitat Ahimastos AA, Formosa M, Dart AM, Kingwell BA (2003) Gender differences in large artery stiffness pre-and post puberty. J Clin Endocrinol Metab 88(11):5375–5380CrossRef Ahimastos AA, Formosa M, Dart AM, Kingwell BA (2003) Gender differences in large artery stiffness pre-and post puberty. J Clin Endocrinol Metab 88(11):5375–5380CrossRef
Zurück zum Zitat Arora S, Stouffer GA, Kucharska-Newton AM, Qamar A, Vaduganathan M, Pandey A, Caughey MC (2019) Twenty year trends and sex differences in young adults hospitalized with acute myocardial infarction: the ARIC Community Surveillance Study. Circulation 139(8):1047–1056CrossRef Arora S, Stouffer GA, Kucharska-Newton AM, Qamar A, Vaduganathan M, Pandey A, Caughey MC (2019) Twenty year trends and sex differences in young adults hospitalized with acute myocardial infarction: the ARIC Community Surveillance Study. Circulation 139(8):1047–1056CrossRef
Zurück zum Zitat Ashor AW, Lara J, Siervo M, Celis-Morales C, Mathers JC (2014) Effects of exercise modalities on arterial stiffness and wave reflection: a systematic review and meta-analysis of randomized controlled trials. PLoS ONE 9(10):e110034CrossRef Ashor AW, Lara J, Siervo M, Celis-Morales C, Mathers JC (2014) Effects of exercise modalities on arterial stiffness and wave reflection: a systematic review and meta-analysis of randomized controlled trials. PLoS ONE 9(10):e110034CrossRef
Zurück zum Zitat Bentley-Lewis R, Koruda K, Seely EW (2007) The metabolic syndrome in women. Nat Clin Pract Endocrinol Metab 3(10):696–704CrossRef Bentley-Lewis R, Koruda K, Seely EW (2007) The metabolic syndrome in women. Nat Clin Pract Endocrinol Metab 3(10):696–704CrossRef
Zurück zum Zitat Bhati P, Moiz JA, Menon GR, Hussain ME (2019) Does resistance training modulate cardiac autonomic control? A systematic review and meta-analysis. Clin Auton Res 29(1):75–103CrossRef Bhati P, Moiz JA, Menon GR, Hussain ME (2019) Does resistance training modulate cardiac autonomic control? A systematic review and meta-analysis. Clin Auton Res 29(1):75–103CrossRef
Zurück zum Zitat Bishop A, DeBeliso M, Sevene TG, Adams KJ (2014) Comparing one repetition maximum and three repetition maximum between conventional and eccentrically loaded deadlifts. The Journal of Strength & Conditioning Research 28(7):1820–1825CrossRef Bishop A, DeBeliso M, Sevene TG, Adams KJ (2014) Comparing one repetition maximum and three repetition maximum between conventional and eccentrically loaded deadlifts. The Journal of Strength & Conditioning Research 28(7):1820–1825CrossRef
Zurück zum Zitat Casey DP, Beck DT, Braith RW (2007) Progressive Resistance Training Without Volume Increases Does Not Alter Arterial Stiffness and Aortic Wave Reflection. Exp Biol Med 232(9):1228–1235CrossRef Casey DP, Beck DT, Braith RW (2007) Progressive Resistance Training Without Volume Increases Does Not Alter Arterial Stiffness and Aortic Wave Reflection. Exp Biol Med 232(9):1228–1235CrossRef
Zurück zum Zitat Cavalcante JL, Lima JA, Redheuil A, Al-Mallah MH (2011) Aortic stiffness: current understanding and future directions. J Am Coll Cardiol 57(14):1511–1522CrossRef Cavalcante JL, Lima JA, Redheuil A, Al-Mallah MH (2011) Aortic stiffness: current understanding and future directions. J Am Coll Cardiol 57(14):1511–1522CrossRef
Zurück zum Zitat Collier SR, Kanaley JA, Carhart R Jr, Frechette V, Tobin MM, Bennett N, Fernhall B (2009) Cardiac autonomic function and baroreflex changes following 4 weeks of resistance versus aerobic training in individuals with pre-hypertension. Acta Physiol 195(3):339–348CrossRef Collier SR, Kanaley JA, Carhart R Jr, Frechette V, Tobin MM, Bennett N, Fernhall B (2009) Cardiac autonomic function and baroreflex changes following 4 weeks of resistance versus aerobic training in individuals with pre-hypertension. Acta Physiol 195(3):339–348CrossRef
Zurück zum Zitat Collier SR, Frechette V, Sandberg K, Schafer P, Ji H, Smulyan H, Fernhall B (2011) Sex differences in resting hemodynamics and arterial stiffness following 4 weeks of resistance versus aerobic exercise training in individuals with pre-hypertension to stage 1 hypertension. Biol Sex Differ 2(1):1–7CrossRef Collier SR, Frechette V, Sandberg K, Schafer P, Ji H, Smulyan H, Fernhall B (2011) Sex differences in resting hemodynamics and arterial stiffness following 4 weeks of resistance versus aerobic exercise training in individuals with pre-hypertension to stage 1 hypertension. Biol Sex Differ 2(1):1–7CrossRef
Zurück zum Zitat Cooke WH, Carter JR (2005) Strength training does not affect vagal–cardiac control or cardiovagal baroreflex sensitivity in young healthy subjects. Eur J Appl Physiol 93(5):719–725CrossRef Cooke WH, Carter JR (2005) Strength training does not affect vagal–cardiac control or cardiovagal baroreflex sensitivity in young healthy subjects. Eur J Appl Physiol 93(5):719–725CrossRef
Zurück zum Zitat Cortez-Cooper MY, DeVan AE, Anton MM, Farrar RP, Beckwith KA, Todd JS, Tanaka H (2005) Effects of high intensity resistance training on arterial stiffness and wave reflection in women. Am J Hypertens 18(7):930–934CrossRef Cortez-Cooper MY, DeVan AE, Anton MM, Farrar RP, Beckwith KA, Todd JS, Tanaka H (2005) Effects of high intensity resistance training on arterial stiffness and wave reflection in women. Am J Hypertens 18(7):930–934CrossRef
Zurück zum Zitat Ernst G (2017) Hidden signals—the history and methods of heart rate variability. Front Public Health 5:265CrossRef Ernst G (2017) Hidden signals—the history and methods of heart rate variability. Front Public Health 5:265CrossRef
Zurück zum Zitat Figueroa A, Okamoto T, Jaime SJ, Fahs CA (2019) Impact of high-and low-intensity resistance training on arterial stiffness and blood pressure in adults across the lifespan: a review. Pflügers Archiv-European Journal of Physiology 471(3):467–478CrossRef Figueroa A, Okamoto T, Jaime SJ, Fahs CA (2019) Impact of high-and low-intensity resistance training on arterial stiffness and blood pressure in adults across the lifespan: a review. Pflügers Archiv-European Journal of Physiology 471(3):467–478CrossRef
Zurück zum Zitat Gambassi B, Schwingel P, Mesquita F, da Penha Carnevali M, de Oliveira D, Sotão SS, Almeida F (2019) Influence of resistance training practice on autonomic cardiac control of hypertensive elderly women. Jeponline 22(1):37–44 Gambassi B, Schwingel P, Mesquita F, da Penha Carnevali M, de Oliveira D, Sotão SS, Almeida F (2019) Influence of resistance training practice on autonomic cardiac control of hypertensive elderly women. Jeponline 22(1):37–44
Zurück zum Zitat Gordan R, Gwathmey JK, Xie LH (2015) Autonomic and endocrine control of cardiovascular function. World J Cardiol 7(4):204CrossRef Gordan R, Gwathmey JK, Xie LH (2015) Autonomic and endocrine control of cardiovascular function. World J Cardiol 7(4):204CrossRef
Zurück zum Zitat Heffernan KS, Collier SR, Kelly EE, Jae SY, Fernhall B (2007a) Arterial stiffness and baroreflex sensitivity following bouts of aerobic and resistance exercise. Int J Sports Med 28(03):197–203CrossRef Heffernan KS, Collier SR, Kelly EE, Jae SY, Fernhall B (2007a) Arterial stiffness and baroreflex sensitivity following bouts of aerobic and resistance exercise. Int J Sports Med 28(03):197–203CrossRef
Zurück zum Zitat Heffernan KS, Jae SY, Edwards DG, Kelly EE, Fernhall B (2007b) Arterial stiffness following repeated Valsalva maneuvers and resistance exercise in young men. Appl Physiol Nutr Metab 32(2):257–264CrossRef Heffernan KS, Jae SY, Edwards DG, Kelly EE, Fernhall B (2007b) Arterial stiffness following repeated Valsalva maneuvers and resistance exercise in young men. Appl Physiol Nutr Metab 32(2):257–264CrossRef
Zurück zum Zitat Iellamo F, Pizzinelli P, Massaro M, Raimondi G, Peruzzi G, Legramante JM (1999) Muscle metaboreflex contribution to sinus node regulation during static exercise: insights from spectral analysis of heart rate variability. Circulation 100(1):27–32CrossRef Iellamo F, Pizzinelli P, Massaro M, Raimondi G, Peruzzi G, Legramante JM (1999) Muscle metaboreflex contribution to sinus node regulation during static exercise: insights from spectral analysis of heart rate variability. Circulation 100(1):27–32CrossRef
Zurück zum Zitat Kanegusuku H, Queiroz AC, Silva VJ, de Mello MT, Ugrinowitsch C, Forjaz CL (2015) High-intensity progressive resistance training increases strength with no change in cardiovascular function and autonomic neural regulation in older adults. J Aging Phys Act 23(3):339–345CrossRef Kanegusuku H, Queiroz AC, Silva VJ, de Mello MT, Ugrinowitsch C, Forjaz CL (2015) High-intensity progressive resistance training increases strength with no change in cardiovascular function and autonomic neural regulation in older adults. J Aging Phys Act 23(3):339–345CrossRef
Zurück zum Zitat Laitinen T, Hartikainen J, Vanninen E, Niskanen L, Geelen G, Länsimies E (1998) Age and gender dependency of baroreflex sensitivity in healthy subjects. J Appl Physiol 84(2):576–583CrossRef Laitinen T, Hartikainen J, Vanninen E, Niskanen L, Geelen G, Länsimies E (1998) Age and gender dependency of baroreflex sensitivity in healthy subjects. J Appl Physiol 84(2):576–583CrossRef
Zurück zum Zitat MacDougall JD, Tuxen DSDG, Sale DG, Moroz JR, Sutton JR (1985) Arterial blood pressure response to heavy resistance exercise. J Appl Physiol 58(3):785–790CrossRef MacDougall JD, Tuxen DSDG, Sale DG, Moroz JR, Sutton JR (1985) Arterial blood pressure response to heavy resistance exercise. J Appl Physiol 58(3):785–790CrossRef
Zurück zum Zitat Mayer F, Scharhag-Rosenberger F, Carlsohn A, Cassel M, Müller S, Scharhag J (2011) The intensity and effects of strength training in the elderly. Dtsch Arztebl Int 108(21):359PubMedPubMedCentral Mayer F, Scharhag-Rosenberger F, Carlsohn A, Cassel M, Müller S, Scharhag J (2011) The intensity and effects of strength training in the elderly. Dtsch Arztebl Int 108(21):359PubMedPubMedCentral
Zurück zum Zitat Mcleod JC, Stokes T, Phillips SM (2019) Resistance exercise training as a primary countermeasure to age-related chronic disease. Frontiers Physiol: 10:645 Mcleod JC, Stokes T, Phillips SM (2019) Resistance exercise training as a primary countermeasure to age-related chronic disease. Frontiers Physiol: 10:645
Zurück zum Zitat Minson CT, Halliwill JR, Young TM, Joyner MJ (2000) Influence of the menstrual cycle on sympathetic activity, baroreflex sensitivity, and vascular transduction in young women. Circulation 101(8):862–868CrossRef Minson CT, Halliwill JR, Young TM, Joyner MJ (2000) Influence of the menstrual cycle on sympathetic activity, baroreflex sensitivity, and vascular transduction in young women. Circulation 101(8):862–868CrossRef
Zurück zum Zitat Miyachi M (2013) Effects of resistance training on arterial stiffness: a meta-analysis. Br J Sports Med 47(6):393–396CrossRef Miyachi M (2013) Effects of resistance training on arterial stiffness: a meta-analysis. Br J Sports Med 47(6):393–396CrossRef
Zurück zum Zitat Mohamed MK, El-Mas MM, Abdel-Rahman AA (1999) Estrogen enhancement of baroreflex sensitivity is centrally mediated. Am J Physiol Regul Integr Comp Physiol 276(4):R1030–R1037CrossRef Mohamed MK, El-Mas MM, Abdel-Rahman AA (1999) Estrogen enhancement of baroreflex sensitivity is centrally mediated. Am J Physiol Regul Integr Comp Physiol 276(4):R1030–R1037CrossRef
Zurück zum Zitat Moritani T, deVries HA (1979) Neural factors versus hypertrophy in the time course of muscle strength gain. Am J Phys Med 58(3):115–130PubMed Moritani T,  deVries HA (1979) Neural factors versus hypertrophy in the time course of muscle strength gain. Am J Phys Med 58(3):115–130PubMed
Zurück zum Zitat Munir S, Jiang B, Guilcher A, Brett S, Redwood S, Marber M, Chowienczyk P (2008) Exercise reduces arterial pressure augmentation through vasodilation of muscular arteries in humans. Am J Physiol Heart Circ Physiol 294(4):H1645–H1650CrossRef Munir S, Jiang B, Guilcher A, Brett S, Redwood S, Marber M, Chowienczyk P (2008) Exercise reduces arterial pressure augmentation through vasodilation of muscular arteries in humans. Am J Physiol Heart Circ Physiol 294(4):H1645–H1650CrossRef
Zurück zum Zitat Nocon M, Hiemann T, Müller-Riemenschneider F, Thalau F, Roll S, Willich SN (2008) Association of physical activity with all-cause and cardiovascular mortality: a systematic review and meta-analysis. Eur J Prev Cardiol 15(3):239–246CrossRef Nocon M, Hiemann T, Müller-Riemenschneider F, Thalau F, Roll S, Willich SN (2008) Association of physical activity with all-cause and cardiovascular mortality: a systematic review and meta-analysis. Eur J Prev Cardiol 15(3):239–246CrossRef
Zurück zum Zitat Palatini P (1999) Heart rate as a risk factor for atherosclerosis and cardiovascular mortality. Drugs 57(5):713–724CrossRef Palatini P (1999) Heart rate as a risk factor for atherosclerosis and cardiovascular mortality. Drugs 57(5):713–724CrossRef
Zurück zum Zitat Rakobowchuk M, McGowan CL, De Groot PC, Bruinsma D, Hartman JW, Phillips SM, MacDonald MJ (2005) Effect of whole body resistance training on arterial compliance in young men. Exp Physiol 90(4):645–651CrossRef Rakobowchuk M, McGowan CL, De Groot PC, Bruinsma D, Hartman JW, Phillips SM, MacDonald MJ (2005) Effect of whole body resistance training on arterial compliance in young men. Exp Physiol 90(4):645–651CrossRef
Zurück zum Zitat Rossow LM, Fahs CA, Thiebaud RS, Loenneke JP, Kim D, Mouser JG, Bemben MG (2014) Arterial stiffness and blood flow adaptations following eight weeks of resistance exercise training in young and older women. Exp Gerontol 53:48–56CrossRef Rossow LM, Fahs CA, Thiebaud RS, Loenneke JP, Kim D, Mouser JG, Bemben MG (2014) Arterial stiffness and blood flow adaptations following eight weeks of resistance exercise training in young and older women. Exp Gerontol 53:48–56CrossRef
Zurück zum Zitat Saleh TM, Connell BJ (2003) Estrogen-induced autonomic effects are mediated by NMDA and GABAA receptors in the parabrachial nucleus. Brain Res 973(2):161–170CrossRef Saleh TM, Connell BJ (2003) Estrogen-induced autonomic effects are mediated by NMDA and GABAA receptors in the parabrachial nucleus. Brain Res 973(2):161–170CrossRef
Zurück zum Zitat Teixeira BC, Boeno FP, Siqueira CV, Cadore EL, Ribeiro JL, Reischak-Oliveira A, dos Santos Cunha G (2019) Strength training enhances endothelial and muscular function in postmenopausal women. Sci Sports 34(2):e147–e154CrossRef Teixeira BC, Boeno FP, Siqueira CV, Cadore EL, Ribeiro JL, Reischak-Oliveira A, dos Santos Cunha G (2019) Strength training enhances endothelial and muscular function in postmenopausal women. Sci Sports 34(2):e147–e154CrossRef
Zurück zum Zitat Vlachopoulos C, Aznaouridis K, O’Rourke MF, Safar ME, Baou K, Stefanadis C (2010a) Prediction of cardiovascular events and all-cause mortality with central haemodynamics: a systematic review and meta-analysis. Eur Heart J 31(15):1865–1871CrossRef Vlachopoulos C, Aznaouridis K, O’Rourke MF, Safar ME, Baou K, Stefanadis C (2010a) Prediction of cardiovascular events and all-cause mortality with central haemodynamics: a systematic review and meta-analysis. Eur Heart J 31(15):1865–1871CrossRef
Zurück zum Zitat Vlachopoulos C, Aznaouridis K, Stefanadis C (2010b) Prediction of cardiovascular events and all-cause mortality with arterial stiffness: a systematic review and meta-analysis. J Am Coll Cardiol 55(13):1318–1327CrossRef Vlachopoulos C, Aznaouridis K, Stefanadis C (2010b) Prediction of cardiovascular events and all-cause mortality with arterial stiffness: a systematic review and meta-analysis. J Am Coll Cardiol 55(13):1318–1327CrossRef
Zurück zum Zitat Watson SL, Weeks BK, Weis LJ, Horan SA, Beck BR (2015) Heavy resistance training is safe and improves bone, function, and stature in postmenopausal women with low to very low bone mass: novel early findings from the LIFTMOR trial. Osteoporos Int 26(12):2889–2894CrossRef Watson SL, Weeks BK, Weis LJ, Horan SA, Beck BR (2015) Heavy resistance training is safe and improves bone, function, and stature in postmenopausal women with low to very low bone mass: novel early findings from the LIFTMOR trial. Osteoporos Int 26(12):2889–2894CrossRef
Zurück zum Zitat Zhang B, Sakai T, Noda K, Kiyonaga A, Tanaka H, Shindo M, Saku K (2003) Multivariate analysis of the prognostic determinants of the depressor response to exercise therapy in patients with essential hypertension. Circ J 67(7):579–584CrossRef Zhang B, Sakai T, Noda K, Kiyonaga A, Tanaka H, Shindo M, Saku K (2003) Multivariate analysis of the prognostic determinants of the depressor response to exercise therapy in patients with essential hypertension. Circ J 67(7):579–584CrossRef
Metadaten
Titel
Central arterial stiffness, wave reflection, and heart rate variability following 4-week high-intensity resistance training intervention in young active women
verfasst von
Sarean Harmoni A. Gaynor-Metzinger
N. Travis Triplett
Marco Meucci
Kimberly S. Fasczewski
Damon H. Flinchum
Scott R. Collier
Publikationsdatum
19.07.2022
Verlag
Springer Berlin Heidelberg
Erschienen in
European Journal of Applied Physiology / Ausgabe 10/2022
Print ISSN: 1439-6319
Elektronische ISSN: 1439-6327
DOI
https://doi.org/10.1007/s00421-022-05003-4

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