Erschienen in:
24.01.2021 | COVID-19 | Review
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Opsoclonus-myoclonus syndrome, a post-infectious neurologic complication of COVID-19: case series and review of literature
verfasst von:
Maziar Emamikhah, Mansoureh Babadi, Mehrnoush Mehrabani, Mehdi Jalili, Maryam Pouranian, Peyman Daraie, Fahimeh Mohaghegh, Sharmin Aghavali, Maryam Zaribafian, Mohammad Rohani
Erschienen in:
Journal of NeuroVirology
|
Ausgabe 1/2021
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Abstract
Opsoclonus-myoclonus-ataxia syndrome is a heterogeneous constellation of symptoms ranging from full combination of these three neurological findings to varying degrees of isolated individual sign. Since the emergence of coronavirus disease 2019 (COVID-19), neurological symptoms, syndromes, and complications associated with this multi-organ viral infection have been reported and the various aspects of neurological involvement are increasingly uncovered. As a neuro-inflammatory disorder, one would expect to observe opsoclonus-myoclonus syndrome after a prevalent viral infection in a pandemic scale, as it has been the case for many other neuro-inflammatory syndromes. We report seven cases of opsoclonus-myoclonus syndrome presumably parainfectious in nature and discuss their phenomenology, their possible pathophysiological relationship to COVID-19, and diagnostic and treatment strategy in each case. Finally, we review the relevant data in the literature regarding the opsoclonus-myoclonus syndrome and possible similar cases associated with COVID-19 and its diagnostic importance for clinicians in various fields of medicine encountering COVID-19 patients and its complications.