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Erschienen in: Infection 4/2022

24.03.2022 | COVID-19 | Brief Report Zur Zeit gratis

COVID-19-associated Cryptococcus infection (CACI): a review of literature and clinical pearls

verfasst von: Dinesh Regalla, Mollie VanNatta, Mohammad Alam, Alexandre E. Malek

Erschienen in: Infection | Ausgabe 4/2022

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Abstract

Background

Cryptococcal infection has been increasingly reported in patients with COVID-19 infection, but the epidemiological factors, presentation, diagnostic certainty, and outcome have not been well-described.

Methods

We reviewed the published cases of COVID-19-associated Cryptococcus infections (CACI) to shed the light on the burden of this infection.

Results

We identified 13 patients with confirmed cryptococcal infection. Cryptococcus infection was primarily seen in patients with severe COVID-19 disease who received corticosteroids therapy and admitted to the intensive care unit. Pulmonary CACI was the most common reported infection followed by cryptococcal meningitis.

Conclusion

In light of the high mortality rate, clinicians should maintain a high clinical suspicion of CACI in critically ill patients.
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Metadaten
Titel
COVID-19-associated Cryptococcus infection (CACI): a review of literature and clinical pearls
verfasst von
Dinesh Regalla
Mollie VanNatta
Mohammad Alam
Alexandre E. Malek
Publikationsdatum
24.03.2022
Verlag
Springer Berlin Heidelberg
Schlagwort
COVID-19
Erschienen in
Infection / Ausgabe 4/2022
Print ISSN: 0300-8126
Elektronische ISSN: 1439-0973
DOI
https://doi.org/10.1007/s15010-022-01805-y

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