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European Journal of Clinical Microbiology & Infectious Diseases

Erschienen in:

25.11.2020 | COVID-19 | Brief Report Zur Zeit gratis

Practical challenges to the clinical implementation of saliva for SARS-CoV-2 detection

verfasst von: Nancy Matic, Aleksandra Stefanovic, Victor Leung, Tanya Lawson, Gordon Ritchie, Lynne Li, Sylvie Champagne, Marc G. Romney, Christopher F. Lowe

Erschienen in: European Journal of Clinical Microbiology & Infectious Diseases | Ausgabe 2/2021

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Abstract

Due to global shortages of flocked nasopharyngeal swabs and appropriate viral transport media during the COVID-19 pandemic, alternate diagnostic specimens for SARS-CoV-2 detection are sought. The accuracy and feasibility of saliva samples collected and transported without specialized collection devices or media were evaluated. Saliva demonstrated good concordance with paired nasopharyngeal swabs for SARS-CoV-2 detection in 67/74 cases (90.5%), though barriers to saliva collection were observed in long-term care residents and outbreak settings. SARS-CoV-2 RNA was stable in human saliva at room temperature for up to 48 h after initial specimen collection, informing appropriate transport time and conditions.

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Titel: Practical challenges to the clinical implementation of saliva for SARS-CoV-2 detection
verfasst von: Nancy Matic
Aleksandra Stefanovic
Victor Leung
Tanya Lawson
Gordon Ritchie
Lynne Li
Sylvie Champagne
Marc G. Romney
Christopher F. Lowe
Publikationsdatum: 25.11.2020
Verlag: Springer Berlin Heidelberg
Schlagwörter: COVID-19
Diagnostik in der Infektiologie
Erschienen in: European Journal of Clinical Microbiology & Infectious Diseases / Ausgabe 2/2021
Print ISSN: 0934-9723
Elektronische ISSN: 1435-4373
DOI: https://doi.org/10.1007/s10096-020-04090-5

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Practical challenges to the clinical implementation of saliva for SARS-CoV-2 detection

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