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Erschienen in: Current Diabetes Reports 9/2022

05.07.2022 | Pediatric Type 2 and Monogenic Diabetes (O Pinhas-Hamiel , Section Editor)

Diabetes Out-of-the-Box: Diabetes Mellitus and Impairment in Hearing and Vision

verfasst von: Noah Gruber, Orit Pinhas-Hamiel

Erschienen in: Current Diabetes Reports | Ausgabe 9/2022

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Abstract

Purposeof Review

This review aims to provide an update on the etiologies of diabetes that are due to genetic disorders and that co-occur with impaired hearing or vision and to compare them. The potential mechanisms, including novel treatments, will be detailed.

Recent Findings

Wolfram syndrome, Kearns–Sayre syndrome, thiamine-responsive megaloblastic anemia, and maternally inherited diabetes and deafness are genetic disorders characterized by diabetes, impaired hearing, and vision. They differ in mode of inheritance, age at presentation, and the involvement of other organs; they are often misdiagnosed as type 1 or type 2 diabetes.

Summary

Suspicion of a genetic diabetes syndrome should be raised when pancreatic autoantibodies are negative, other organs are involved, and family history includes diabetes. Correct diagnosis of the various syndromes is important for tailoring the most advanced treatment, preventing disease progression, and enabling proper genetic counseling.
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Metadaten
Titel
Diabetes Out-of-the-Box: Diabetes Mellitus and Impairment in Hearing and Vision
verfasst von
Noah Gruber
Orit Pinhas-Hamiel
Publikationsdatum
05.07.2022
Verlag
Springer US
Erschienen in
Current Diabetes Reports / Ausgabe 9/2022
Print ISSN: 1534-4827
Elektronische ISSN: 1539-0829
DOI
https://doi.org/10.1007/s11892-022-01483-y

Weitere Artikel der Ausgabe 9/2022

Current Diabetes Reports 9/2022 Zur Ausgabe

Pathogenesis of Type 2 Diabetes and Insulin Resistance (M-E Patti, Section Editor)

Lipodystrophy for the Diabetologist—What to Look For

Hospital Management of Diabetes (A Wallia and J Jeffrie Seley, Section Editors)

Pharmacist Role in Providing Inpatient Diabetes Management

Health Care Delivery Systems and Implementation in Diabetes (ME McDonnell and AR Sadhu, Section Editor)

Electronic Health Record–Based Decision-Making Support in Inpatient Diabetes Management

Hospital Management of Diabetes (A Wallia and JJ Seley, Section Editors)

CGM in the Hospital: Is It Ready for Prime Time?

Update Innere Medizin

Update Innere Medizin

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