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Drugs in R&D

Ausgabe 1/2022

Inhalt (12 Artikel)

Open Access Current Opinion

The Pitfalls of Abnormal Laboratory Value Interpretation in Vaccine Clinical Trials: The Example of Asymptomatic Transient Neutropenia

Venanzio Vella, Johannes E. Schmidt, Giulia Luna Cilio, Iris De Ryck, Audino Podda, Valentino Conti, Joachim Auerbach

Open Access Review Article

Pharmacokinetics and Pharmacodynamics of Ibrexafungerp

Matthew William McCarthy

Open Access Original Research Article

Pharmacokinetics and Bioequivalence of Sitagliptin Phosphate/Metformin Hydrochloride Tablets in Healthy Chinese Subjects: A Randomized, Open-Label, Crossover Study

Ping Shi, Xin Liu, Ting Li, Fei-fei Sun, Yan-ping Liu, Shu-qin Liu, Xiao-meng Gao, Ya-ping Ma, Yao Fu, Yu Cao

Open Access Original Research Article

Coenzyme Q10 in the Treatment of Heart Failure with Preserved Ejection Fraction: A Prospective, Randomized, Double-Blind, Placebo-Controlled Trial

Tal Y. Samuel, Tal Hasin, Israel Gotsman, Tanya Weitzman, Fanny Ben Ivgi, Ziv Dadon, Elad Asher, Offer Amir, Michael Glikson, Ronny Alcalai, David Leibowitz

Open Access Original Research Article

An Evaluation of the Pharmacokinetics, Safety, and Tolerability of Aclidinium/Formoterol Fixed-Dose Combination Administered in Chinese Patients with Moderate-to-Severe Chronic Obstructive Pulmonary Disease

Hong Zhang, Sami Z. Daoud, Michael S. Gillen, Natalia Calderon, Maria Heijer, Eduard Molins, Esther Garcia-Gil, Hong Chen, Qianqian Li, Chengjiao Liu, Yanhua Ding

Open Access Original Research Article

Pharmacokinetics of Diazepam and Its Metabolites in Urine of Chinese Participants

Le-le Wang, Xin-xin Ren, Yi He, Guan-feng Cui, Jia-jia Liu, Juan Jia, Jie Cao, Yao Liu, Bin Cong, Zhi-wen Wei, Ke-ming Yun

Open Access Original Research Article

Safety, Pharmacokinetic, and Pharmacodynamic Study of a Sublingual Formula for the Treatment of Vasovagal Syncope

Paul Hutson, Regis Guieu, Jean-Claude Deharo, Pierre Michelet, Michele Brignole, Cassondra Vander Ark, Mohamed H. Hamdan

Open Access Original Research Article

Effect of Severe Renal Impairment on the Safety, Tolerability, and Pharmacokinetics of AMG 986

Ashit Trivedi, Omar Mather, Silvia Vega, Mary Ann Simiens, Jennifer Hellawell, Edward Lee

Open Access Original Research Article

In Vitro Stability and Recovery Studies of Pimavanserin in Water and in Different Vehicles Orally Administered

Allan David Bokser, Yvonne Holmes Adegbenle, Vesna Stoisavljevic, James C. Norton