Skip to main content
Erschienen in: Clinical Autonomic Research 2/2023

28.04.2023 | Research Article

Effects of posture changes on dynamic cerebral autoregulation during early pregnancy in women with obesity and/or sleep apnea

verfasst von: Takuro Washio, Sarah L. Hissen, Ryosuke Takeda, Kazumasa Manabe, John D. Akins, Belinda Sanchez, Andrew W. D’Souza, David B. Nelson, Safia Khan, Andrew R. Tomlinson, Tony G. Babb, Qi Fu

Erschienen in: Clinical Autonomic Research | Ausgabe 2/2023

Einloggen, um Zugang zu erhalten

Abstract

The incidence of syncope during orthostasis increases in early human pregnancy, which may be associated with cerebral blood flow (CBF) dysregulation in the upright posture. In addition, obesity and/or sleep apnea per se may influence CBF regulation due to their detrimental impacts on cerebrovascular function. However, it is unknown whether early pregnant women with obesity and/or sleep apnea could have impaired CBF regulation in the supine position and whether this impairment would be further exacerbated in the upright posture. Dynamic cerebral autoregulation (CA) was evaluated using transfer function analysis in 33 women during early pregnancy (13 with obesity, 8 with sleep apnea, 12 with normal weight) and 15 age-matched nonpregnant women during supine rest. Pregnant women also underwent a graded head-up tilt (30° and 60° for 6 min each). We found that pregnant women with obesity or sleep apnea had a higher transfer function low-frequency gain compared with nonpregnant women in the supine position (P = 0.026 and 0.009, respectively) but not normal-weight pregnant women (P = 0.945). Conversely, the transfer function low-frequency phase in all pregnancy groups decreased during head-up tilt (P = 0.001), but the phase was not different among pregnant groups (P = 0.180). These results suggest that both obesity and sleep apnea may have a detrimental effect on dynamic CA in the supine position during early pregnancy. CBF may be more vulnerable to spontaneous blood pressure fluctuations in early pregnant women during orthostatic stress compared with supine rest due to less efficient dynamic CA, regardless of obesity and/or sleep apnea.
Anhänge
Nur mit Berechtigung zugänglich
Literatur
1.
Zurück zum Zitat Aaslid R, Lindegaard KF, Sorteberg W, Nornes H (1989) Cerebral autoregulation dynamics in humans. Stroke 20:45–52PubMedCrossRef Aaslid R, Lindegaard KF, Sorteberg W, Nornes H (1989) Cerebral autoregulation dynamics in humans. Stroke 20:45–52PubMedCrossRef
2.
Zurück zum Zitat Anne K. Driscoll ECWG (2020) Increases in Prepregnancy Obesity: United States, 2016–2019 NCHS Data Brief No. 392 Anne K. Driscoll ECWG (2020) Increases in Prepregnancy Obesity: United States, 2016–2019 NCHS Data Brief No. 392
4.
Zurück zum Zitat Bergman L, Cluver C, Carlberg N, Belfort M, Tolcher MC, Panerai RB, van Veen T (2021) Cerebral perfusion pressure and autoregulation in eclampsia-a case control study. Am J Obstet Gynecol 225:181–185CrossRef Bergman L, Cluver C, Carlberg N, Belfort M, Tolcher MC, Panerai RB, van Veen T (2021) Cerebral perfusion pressure and autoregulation in eclampsia-a case control study. Am J Obstet Gynecol 225:181–185CrossRef
5.
Zurück zum Zitat Berry RB, Budhiraja R, Gottlieb DJ, Gozal D, Iber C, Kapur VK, Marcus CL, Mehra R, Parthasarathy S, Quan SF, Redline S, Strohl KP, Davidson Ward SL, Tangredi MM, American Academy of Sleep M (2012) Rules for scoring respiratory events in sleep: update of the 2007 AASM manual for the scoring of sleep and associated events. deliberations of the sleep apnea definitions task force of the american academy of sleep medicine. J Clin Sleep Med 8:597–619PubMedPubMedCentralCrossRef Berry RB, Budhiraja R, Gottlieb DJ, Gozal D, Iber C, Kapur VK, Marcus CL, Mehra R, Parthasarathy S, Quan SF, Redline S, Strohl KP, Davidson Ward SL, Tangredi MM, American Academy of Sleep M (2012) Rules for scoring respiratory events in sleep: update of the 2007 AASM manual for the scoring of sleep and associated events. deliberations of the sleep apnea definitions task force of the american academy of sleep medicine. J Clin Sleep Med 8:597–619PubMedPubMedCentralCrossRef
6.
Zurück zum Zitat Bisson M, Almeras N, Plaisance J, Rheaume C, Bujold E, Tremblay A, Marc I (2013) Maternal fitness at the onset of the second trimester of pregnancy: correlates and relationship with infant birth weight. Pediatr Obes 8:464–474PubMedCrossRef Bisson M, Almeras N, Plaisance J, Rheaume C, Bujold E, Tremblay A, Marc I (2013) Maternal fitness at the onset of the second trimester of pregnancy: correlates and relationship with infant birth weight. Pediatr Obes 8:464–474PubMedCrossRef
7.
Zurück zum Zitat Bliss ES, Wong RH, Howe PR, Mills DE (2021) Benefits of exercise training on cerebrovascular and cognitive function in ageing. J Cereb Blood Flow Metab 41:447–470PubMedCrossRef Bliss ES, Wong RH, Howe PR, Mills DE (2021) Benefits of exercise training on cerebrovascular and cognitive function in ageing. J Cereb Blood Flow Metab 41:447–470PubMedCrossRef
8.
Zurück zum Zitat Boccatonda A, Tripaldi R, Davi G, Santilli F (2016) Oxidative stress modulation through habitual physical activity. Curr Pharm Des 22:3648–3680PubMedCrossRef Boccatonda A, Tripaldi R, Davi G, Santilli F (2016) Oxidative stress modulation through habitual physical activity. Curr Pharm Des 22:3648–3680PubMedCrossRef
9.
Zurück zum Zitat Brassard P, Ferland-Dutil H, Smirl JD, Paquette M, Le Blanc O, Malenfant S, Ainslie PN (2017) Evidence for hysteresis in the cerebral pressure-flow relationship in healthy men. Am J Physiol Heart Circ Physiol 312:H701–H704PubMedCrossRef Brassard P, Ferland-Dutil H, Smirl JD, Paquette M, Le Blanc O, Malenfant S, Ainslie PN (2017) Evidence for hysteresis in the cerebral pressure-flow relationship in healthy men. Am J Physiol Heart Circ Physiol 312:H701–H704PubMedCrossRef
10.
Zurück zum Zitat Brassard P, Labrecque L, Smirl JD, Tymko MM, Caldwell HG, Hoiland RL, Lucas SJE, Denault AY, Couture EJ, Ainslie PN (2021) Losing the dogmatic view of cerebral autoregulation. Physiol Rep 9:e14982PubMedPubMedCentralCrossRef Brassard P, Labrecque L, Smirl JD, Tymko MM, Caldwell HG, Hoiland RL, Lucas SJE, Denault AY, Couture EJ, Ainslie PN (2021) Losing the dogmatic view of cerebral autoregulation. Physiol Rep 9:e14982PubMedPubMedCentralCrossRef
11.
Zurück zum Zitat Brislane A, Jones H, Holder SM, Low DA, Hopkins ND (2021) The effect of exercise during pregnancy on maternal and offspring vascular outcomes: a pilot study. Reprod Sci 28:510–523PubMedCrossRef Brislane A, Jones H, Holder SM, Low DA, Hopkins ND (2021) The effect of exercise during pregnancy on maternal and offspring vascular outcomes: a pilot study. Reprod Sci 28:510–523PubMedCrossRef
12.
Zurück zum Zitat Cai H, Wang S, Zou R, Liu P, Li F, Wang Y, Wang C (2021) Comparison of the active sitting test and head-up tilt test for diagnosis of postural tachycardia syndrome in children and adolescents. Front Pediatr 9:691390PubMedPubMedCentralCrossRef Cai H, Wang S, Zou R, Liu P, Li F, Wang Y, Wang C (2021) Comparison of the active sitting test and head-up tilt test for diagnosis of postural tachycardia syndrome in children and adolescents. Front Pediatr 9:691390PubMedPubMedCentralCrossRef
13.
Zurück zum Zitat Carey BJ, Manktelow BN, Panerai RB, Potter JF (2001) Cerebral autoregulatory responses to head-up tilt in normal subjects and patients with recurrent vasovagal syncope. Circulation 104:898–902PubMedCrossRef Carey BJ, Manktelow BN, Panerai RB, Potter JF (2001) Cerebral autoregulatory responses to head-up tilt in normal subjects and patients with recurrent vasovagal syncope. Circulation 104:898–902PubMedCrossRef
14.
Zurück zum Zitat Chatur S, Islam S, Moore LE, Sandhu RK, Sheldon RS, Kaul P (2019) Incidence of Syncope During Pregnancy: Temporal Trends and Outcomes. J Am Heart Assoc 8:e011608PubMedPubMedCentralCrossRef Chatur S, Islam S, Moore LE, Sandhu RK, Sheldon RS, Kaul P (2019) Incidence of Syncope During Pregnancy: Temporal Trends and Outcomes. J Am Heart Assoc 8:e011608PubMedPubMedCentralCrossRef
15.
Zurück zum Zitat Claassen J, Thijssen DHJ, Panerai RB, Faraci FM (2021) Regulation of cerebral blood flow in humans: physiology and clinical implications of autoregulation. Physiol Rev 101:1487–1559PubMedPubMedCentralCrossRef Claassen J, Thijssen DHJ, Panerai RB, Faraci FM (2021) Regulation of cerebral blood flow in humans: physiology and clinical implications of autoregulation. Physiol Rev 101:1487–1559PubMedPubMedCentralCrossRef
16.
Zurück zum Zitat Claassen JA, Meel-van den Abeelen AS, Simpson DM, Panerai RB, International Cerebral Autoregulation Research N (2016) Transfer function analysis of dynamic cerebral autoregulation: a white paper from the international cerebral autoregulation research network. J Cereb Blood Flow Metab 36:665–680PubMedPubMedCentralCrossRef Claassen JA, Meel-van den Abeelen AS, Simpson DM, Panerai RB, International Cerebral Autoregulation Research N (2016) Transfer function analysis of dynamic cerebral autoregulation: a white paper from the international cerebral autoregulation research network. J Cereb Blood Flow Metab 36:665–680PubMedPubMedCentralCrossRef
17.
Zurück zum Zitat Collop NA, Anderson WM, Boehlecke B, Claman D, Goldberg R, Gottlieb DJ, Hudgel D, Sateia M, Schwab R, Portable Monitoring Task Force of the American Academy of Sleep M (2007) Clinical guidelines for the use of unattended portable monitors in the diagnosis of obstructive sleep apnea in adult patients. portable monitoring task force of the american academy of sleep medicine. J Clin Sleep Med 3:737–747PubMedCrossRef Collop NA, Anderson WM, Boehlecke B, Claman D, Goldberg R, Gottlieb DJ, Hudgel D, Sateia M, Schwab R, Portable Monitoring Task Force of the American Academy of Sleep M (2007) Clinical guidelines for the use of unattended portable monitors in the diagnosis of obstructive sleep apnea in adult patients. portable monitoring task force of the american academy of sleep medicine. J Clin Sleep Med 3:737–747PubMedCrossRef
18.
Zurück zum Zitat Dominguez JE, Krystal AD, Habib AS (2018) Obstructive sleep apnea in pregnant women: a review of pregnancy outcomes and an approach to management. Anesth Analg 127:1167–1177PubMedPubMedCentralCrossRef Dominguez JE, Krystal AD, Habib AS (2018) Obstructive sleep apnea in pregnant women: a review of pregnancy outcomes and an approach to management. Anesth Analg 127:1167–1177PubMedPubMedCentralCrossRef
20.
Zurück zum Zitat Drapeau A, Labrecque L, Imhoff S, Paquette M, Le Blanc O, Malenfant S, Brassard P (2019) Six weeks of high-intensity interval training to exhaustion attenuates dynamic cerebral autoregulation without influencing resting cerebral blood velocity in young fit men. Physiol Rep 7:e14185PubMedPubMedCentralCrossRef Drapeau A, Labrecque L, Imhoff S, Paquette M, Le Blanc O, Malenfant S, Brassard P (2019) Six weeks of high-intensity interval training to exhaustion attenuates dynamic cerebral autoregulation without influencing resting cerebral blood velocity in young fit men. Physiol Rep 7:e14185PubMedPubMedCentralCrossRef
22.
Zurück zum Zitat Elting JW, Sanders ML, Panerai RB, Aries M, Bor-Seng-Shu E, Caicedo A, Chacon M, Gommer ED, Van Huffel S, Jara JL, Kostoglou K, Mahdi A, Marmarelis VZ, Mitsis GD, Muller M, Nikolic D, Nogueira RC, Payne SJ, Puppo C, Shin DC, Simpson DM, Tarumi T, Yelicich B, Zhang R, Claassen J (2020) Assessment of dynamic cerebral autoregulation in humans: Is reproducibility dependent on blood pressure variability? PLoS ONE 15:e0227651PubMedPubMedCentralCrossRef Elting JW, Sanders ML, Panerai RB, Aries M, Bor-Seng-Shu E, Caicedo A, Chacon M, Gommer ED, Van Huffel S, Jara JL, Kostoglou K, Mahdi A, Marmarelis VZ, Mitsis GD, Muller M, Nikolic D, Nogueira RC, Payne SJ, Puppo C, Shin DC, Simpson DM, Tarumi T, Yelicich B, Zhang R, Claassen J (2020) Assessment of dynamic cerebral autoregulation in humans: Is reproducibility dependent on blood pressure variability? PLoS ONE 15:e0227651PubMedPubMedCentralCrossRef
23.
Zurück zum Zitat Facco FL, Ouyang DW, Zee PC, Grobman WA (2014) Sleep disordered breathing in a high-risk cohort prevalence and severity across pregnancy. Am J Perinatol 31:899–904PubMedPubMedCentralCrossRef Facco FL, Ouyang DW, Zee PC, Grobman WA (2014) Sleep disordered breathing in a high-risk cohort prevalence and severity across pregnancy. Am J Perinatol 31:899–904PubMedPubMedCentralCrossRef
24.
Zurück zum Zitat Facco FL, Parker CB, Reddy UM, Silver RM, Koch MA, Louis JM, Basner RC, Chung JH, Nhan-Chang CL, Pien GW, Redline S, Grobman WA, Wing DA, Simhan HN, Haas DM, Mercer BM, Parry S, Mobley D, Hunter S, Saade GR, Schubert FP, Zee PC (2017) Association between sleep-disordered breathing and hypertensive disorders of pregnancy and gestational diabetes mellitus. Obstet Gynecol 129:31–41PubMedPubMedCentralCrossRef Facco FL, Parker CB, Reddy UM, Silver RM, Koch MA, Louis JM, Basner RC, Chung JH, Nhan-Chang CL, Pien GW, Redline S, Grobman WA, Wing DA, Simhan HN, Haas DM, Mercer BM, Parry S, Mobley D, Hunter S, Saade GR, Schubert FP, Zee PC (2017) Association between sleep-disordered breathing and hypertensive disorders of pregnancy and gestational diabetes mellitus. Obstet Gynecol 129:31–41PubMedPubMedCentralCrossRef
25.
Zurück zum Zitat Favre ME, Lim V, Falvo MJ, Serrador JM (2020) Cerebrovascular reactivity and cerebral autoregulation are improved in the supine posture compared to upright in healthy men and women. PLoS ONE 15:e0229049PubMedPubMedCentralCrossRef Favre ME, Lim V, Falvo MJ, Serrador JM (2020) Cerebrovascular reactivity and cerebral autoregulation are improved in the supine posture compared to upright in healthy men and women. PLoS ONE 15:e0229049PubMedPubMedCentralCrossRef
26.
27.
Zurück zum Zitat G. Carter CKaAN, (1973) Estimation of the magnitude-squared coherence function via overlapped fast Fourier transform processing. IEEE Trans Audio Electroacoust 21:337–344CrossRef G. Carter CKaAN, (1973) Estimation of the magnitude-squared coherence function via overlapped fast Fourier transform processing. IEEE Trans Audio Electroacoust 21:337–344CrossRef
28.
Zurück zum Zitat Garrett ZK, Pearson J, Subudhi AW (2017) Postural effects on cerebral blood flow and autoregulation. Physiol Rep 5:13150CrossRef Garrett ZK, Pearson J, Subudhi AW (2017) Postural effects on cerebral blood flow and autoregulation. Physiol Rep 5:13150CrossRef
29.
Zurück zum Zitat Ghesquiere L, Deruelle P, Ramdane Y, Garabedian C, Charley-Monaca C, Dalmas AF (2020) Obstructive sleep apnea in obese pregnant women: A prospective study. PLoS ONE 15:e0238733PubMedPubMedCentralCrossRef Ghesquiere L, Deruelle P, Ramdane Y, Garabedian C, Charley-Monaca C, Dalmas AF (2020) Obstructive sleep apnea in obese pregnant women: A prospective study. PLoS ONE 15:e0238733PubMedPubMedCentralCrossRef
30.
Zurück zum Zitat Hedner J, Pillar G, Pittman SD, Zou D, Grote L, White DP (2004) A novel adaptive wrist actigraphy algorithm for sleep-wake assessment in sleep apnea patients. Sleep 27:1560–1566PubMedCrossRef Hedner J, Pillar G, Pittman SD, Zou D, Grote L, White DP (2004) A novel adaptive wrist actigraphy algorithm for sleep-wake assessment in sleep apnea patients. Sleep 27:1560–1566PubMedCrossRef
31.
32.
Zurück zum Zitat Ichikawa D, Miyazawa T, Horiuchi M, Kitama T, Fisher JP, Ogoh S (2013) Relationship between aerobic endurance training and dynamic cerebral blood flow regulation in humans. Scand J Med Sci Sports 23:e320-329PubMed Ichikawa D, Miyazawa T, Horiuchi M, Kitama T, Fisher JP, Ogoh S (2013) Relationship between aerobic endurance training and dynamic cerebral blood flow regulation in humans. Scand J Med Sci Sports 23:e320-329PubMed
33.
Zurück zum Zitat Janzarik WG, Ehlers E, Ehmann R, Gerds TA, Schork J, Mayer S, Gabriel B, Weiller C, Prompeler H, Reinhard M (2014) Dynamic cerebral autoregulation in pregnancy and the risk of preeclampsia. Hypertension 63:161–166PubMedCrossRef Janzarik WG, Ehlers E, Ehmann R, Gerds TA, Schork J, Mayer S, Gabriel B, Weiller C, Prompeler H, Reinhard M (2014) Dynamic cerebral autoregulation in pregnancy and the risk of preeclampsia. Hypertension 63:161–166PubMedCrossRef
34.
Zurück zum Zitat Jarvis SS, Shibata S, Bivens TB, Okada Y, Casey BM, Levine BD, Fu Q (2012) Sympathetic activation during early pregnancy in humans. J Physiol 590:3535–3543PubMedPubMedCentralCrossRef Jarvis SS, Shibata S, Bivens TB, Okada Y, Casey BM, Levine BD, Fu Q (2012) Sympathetic activation during early pregnancy in humans. J Physiol 590:3535–3543PubMedPubMedCentralCrossRef
35.
Zurück zum Zitat Kay VL, Rickards CA (2016) The role of cerebral oxygenation and regional cerebral blood flow on tolerance to central hypovolemia. Am J Physiol Regul Integr Comp Physiol 310:R375-383PubMedCrossRef Kay VL, Rickards CA (2016) The role of cerebral oxygenation and regional cerebral blood flow on tolerance to central hypovolemia. Am J Physiol Regul Integr Comp Physiol 310:R375-383PubMedCrossRef
36.
Zurück zum Zitat Labrecque L, Rahimaly K, Imhoff S, Paquette M, Le Blanc O, Malenfant S, Lucas SJE, Bailey DM, Smirl JD, Brassard P (2017) Diminished dynamic cerebral autoregulatory capacity with forced oscillations in mean arterial pressure with elevated cardiorespiratory fitness. Physiol Rep 5:2859CrossRef Labrecque L, Rahimaly K, Imhoff S, Paquette M, Le Blanc O, Malenfant S, Lucas SJE, Bailey DM, Smirl JD, Brassard P (2017) Diminished dynamic cerebral autoregulatory capacity with forced oscillations in mean arterial pressure with elevated cardiorespiratory fitness. Physiol Rep 5:2859CrossRef
37.
Zurück zum Zitat Labrecque L, Smirl JD, Tzeng YC, Brassard P (2022) Point/counterpoint: We should take the direction of blood pressure change into consideration for dynamic cerebral autoregulation quantification. J Cereb Blood Flow Metab 42:2851CrossRef Labrecque L, Smirl JD, Tzeng YC, Brassard P (2022) Point/counterpoint: We should take the direction of blood pressure change into consideration for dynamic cerebral autoregulation quantification. J Cereb Blood Flow Metab 42:2851CrossRef
38.
Zurück zum Zitat Lee JF, Harrison ML, Christmas KM, Kim K, Hurr C, Brothers RM (2014) Elevated resting heart rate and reduced orthostatic tolerance in obese humans. Clin Auton Res 24:39–46PubMedCrossRef Lee JF, Harrison ML, Christmas KM, Kim K, Hurr C, Brothers RM (2014) Elevated resting heart rate and reduced orthostatic tolerance in obese humans. Clin Auton Res 24:39–46PubMedCrossRef
39.
Zurück zum Zitat Lee KK, Raja EA, Lee AJ, Bhattacharya S, Bhattacharya S, Norman JE, Reynolds RM (2015) Maternal obesity during pregnancy associates with premature mortality and major cardiovascular events in later life. Hypertension 66:938–944PubMedCrossRef Lee KK, Raja EA, Lee AJ, Bhattacharya S, Bhattacharya S, Norman JE, Reynolds RM (2015) Maternal obesity during pregnancy associates with premature mortality and major cardiovascular events in later life. Hypertension 66:938–944PubMedCrossRef
40.
Zurück zum Zitat Lind-Holst M, Cotter JD, Helge JW, Boushel R, Augustesen H, Van Lieshout JJ (1985) Pott FC (2011) cerebral autoregulation dynamics in endurance-trained individuals. J Appl Physiol 110:1327–1333CrossRef Lind-Holst M, Cotter JD, Helge JW, Boushel R, Augustesen H, Van Lieshout JJ (1985) Pott FC (2011) cerebral autoregulation dynamics in endurance-trained individuals. J Appl Physiol 110:1327–1333CrossRef
41.
Zurück zum Zitat Liu XJ, Wang S, Zhao YL, Zhang D, Zhao JZ (2011) A single-center study of hemorrhagic stroke caused by cerebrovascular disease during pregnancy and puerperium in China. Int J Gynaecol Obstet 113:82–83PubMedCrossRef Liu XJ, Wang S, Zhao YL, Zhang D, Zhao JZ (2011) A single-center study of hemorrhagic stroke caused by cerebrovascular disease during pregnancy and puerperium in China. Int J Gynaecol Obstet 113:82–83PubMedCrossRef
42.
Zurück zum Zitat Lopez-Jaramillo P, Barajas J, Rueda-Quijano SM, Lopez-Lopez C, Felix C (2018) Obesity and preeclampsia: common pathophysiological mechanisms. Front Physiol 9:1838PubMedPubMedCentralCrossRef Lopez-Jaramillo P, Barajas J, Rueda-Quijano SM, Lopez-Lopez C, Felix C (2018) Obesity and preeclampsia: common pathophysiological mechanisms. Front Physiol 9:1838PubMedPubMedCentralCrossRef
43.
Zurück zum Zitat Mahendru AA, Everett TR, Wilkinson IB, Lees CC, McEniery CM (2014) A longitudinal study of maternal cardiovascular function from preconception to the postpartum period. J Hypertens 32:849–856PubMedCrossRef Mahendru AA, Everett TR, Wilkinson IB, Lees CC, McEniery CM (2014) A longitudinal study of maternal cardiovascular function from preconception to the postpartum period. J Hypertens 32:849–856PubMedCrossRef
44.
Zurück zum Zitat Matsushima R, Tanaka H, Tamai H (2004) Comparison of the active standing test and head-up tilt test for diagnosis of syncope in childhood and adolescence. Clin Auton Res 14:376–384PubMedCrossRef Matsushima R, Tanaka H, Tamai H (2004) Comparison of the active standing test and head-up tilt test for diagnosis of syncope in childhood and adolescence. Clin Auton Res 14:376–384PubMedCrossRef
45.
Zurück zum Zitat Meng L, Gelb AW (2015) Regulation of cerebral autoregulation by carbon dioxide. Anesthesiology 122:196–205PubMedCrossRef Meng L, Gelb AW (2015) Regulation of cerebral autoregulation by carbon dioxide. Anesthesiology 122:196–205PubMedCrossRef
46.
Zurück zum Zitat Mor G, Cardenas I, Abrahams V, Guller S (2011) Inflammation and pregnancy: the role of the immune system at the implantation site. Ann N Y Acad Sci 1221:80–87PubMedPubMedCentralCrossRef Mor G, Cardenas I, Abrahams V, Guller S (2011) Inflammation and pregnancy: the role of the immune system at the implantation site. Ann N Y Acad Sci 1221:80–87PubMedPubMedCentralCrossRef
47.
Zurück zum Zitat Nasr N, Traon AP, Czosnyka M, Tiberge M, Schmidt E, Larrue V (2009) Cerebral autoregulation in patients with obstructive sleep apnea syndrome during wakefulness. Eur J Neurol 16:386–391PubMedCrossRef Nasr N, Traon AP, Czosnyka M, Tiberge M, Schmidt E, Larrue V (2009) Cerebral autoregulation in patients with obstructive sleep apnea syndrome during wakefulness. Eur J Neurol 16:386–391PubMedCrossRef
48.
Zurück zum Zitat O’Brien LM, Bullough AS, Shelgikar AV, Chames MC, Armitage R, Chervin RD (2012) Validation of Watch-PAT-200 against polysomnography during pregnancy. J Clin Sleep Med 8:287–294PubMedPubMedCentralCrossRef O’Brien LM, Bullough AS, Shelgikar AV, Chames MC, Armitage R, Chervin RD (2012) Validation of Watch-PAT-200 against polysomnography during pregnancy. J Clin Sleep Med 8:287–294PubMedPubMedCentralCrossRef
49.
Zurück zum Zitat Ogoh S, Fadel PJ, Zhang R, Selmer C, Jans O, Secher NH, Raven PB (2005) Middle cerebral artery flow velocity and pulse pressure during dynamic exercise in humans. Am J Physiol Heart Circ Physiol 288:H1526-1531PubMedCrossRef Ogoh S, Fadel PJ, Zhang R, Selmer C, Jans O, Secher NH, Raven PB (2005) Middle cerebral artery flow velocity and pulse pressure during dynamic exercise in humans. Am J Physiol Heart Circ Physiol 288:H1526-1531PubMedCrossRef
50.
Zurück zum Zitat Ogoh S, Sato K, Okazaki K, Miyamoto T, Hirasawa A, Sadamoto T, Shibasaki M (2015) Blood flow in internal carotid and vertebral arteries during graded lower body negative pressure in humans. Exp Physiol 100:259–266PubMedCrossRef Ogoh S, Sato K, Okazaki K, Miyamoto T, Hirasawa A, Sadamoto T, Shibasaki M (2015) Blood flow in internal carotid and vertebral arteries during graded lower body negative pressure in humans. Exp Physiol 100:259–266PubMedCrossRef
51.
Zurück zum Zitat Panerai RB, Barnes SC, Batterham AP, Robinson TG, Haunton VJ (2022) Directional sensitivity of dynamic cerebral autoregulation during spontaneous fluctuations in arterial blood pressure at rest. J Cereb Blood Flow Metab 33:271678 Panerai RB, Barnes SC, Batterham AP, Robinson TG, Haunton VJ (2022) Directional sensitivity of dynamic cerebral autoregulation during spontaneous fluctuations in arterial blood pressure at rest. J Cereb Blood Flow Metab 33:271678
52.
Zurück zum Zitat Panerai RB, Brassard P, Burma JS, Castro P, Claassen JA, van Lieshout JJ, Liu J, Lucas SJ, Minhas JS, Mitsis GD, Nogueira RC, Ogoh S, Payne SJ, Rickards CA, Robertson AD, Rodrigues GD, Smirl JD, Simpson DM, Cerebrovascular Research N (2022) Transfer function analysis of dynamic cerebral autoregulation: a CARNet white paper 2022 update. J Cereb Blood Flow Metab 27:1678 Panerai RB, Brassard P, Burma JS, Castro P, Claassen JA, van Lieshout JJ, Liu J, Lucas SJ, Minhas JS, Mitsis GD, Nogueira RC, Ogoh S, Payne SJ, Rickards CA, Robertson AD, Rodrigues GD, Smirl JD, Simpson DM, Cerebrovascular Research N (2022) Transfer function analysis of dynamic cerebral autoregulation: a CARNet white paper 2022 update. J Cereb Blood Flow Metab 27:1678
53.
54.
Zurück zum Zitat Plash WB, Diedrich A, Biaggioni I, Garland EM, Paranjape SY, Black BK, Dupont WD, Raj SR (2013) Diagnosing postural tachycardia syndrome: comparison of tilt testing compared with standing haemodynamics. Clin Sci (Lond) 124:109–114PubMedCrossRef Plash WB, Diedrich A, Biaggioni I, Garland EM, Paranjape SY, Black BK, Dupont WD, Raj SR (2013) Diagnosing postural tachycardia syndrome: comparison of tilt testing compared with standing haemodynamics. Clin Sci (Lond) 124:109–114PubMedCrossRef
55.
Zurück zum Zitat Riberholt CG, Olesen ND, Thing M, Juhl CB, Mehlsen J, Petersen TH (2016) Impaired cerebral autoregulation during head up tilt in patients with severe brain injury. PLoS ONE 11:e0154831PubMedPubMedCentralCrossRef Riberholt CG, Olesen ND, Thing M, Juhl CB, Mehlsen J, Petersen TH (2016) Impaired cerebral autoregulation during head up tilt in patients with severe brain injury. PLoS ONE 11:e0154831PubMedPubMedCentralCrossRef
56.
Zurück zum Zitat Sanders ML, Elting JWJ, Panerai RB, Aries M, Bor-Seng-Shu E, Caicedo A, Chacon M, Gommer ED, Van Huffel S, Jara JL, Kostoglou K, Mahdi A, Marmarelis VZ, Mitsis GD, Muller M, Nikolic D, Nogueira RC, Payne SJ, Puppo C, Shin DC, Simpson DM, Tarumi T, Yelicich B, Zhang R, Claassen J (2019) Dynamic cerebral autoregulation reproducibility is affected by physiological variability. Front Physiol 10:865PubMedPubMedCentralCrossRef Sanders ML, Elting JWJ, Panerai RB, Aries M, Bor-Seng-Shu E, Caicedo A, Chacon M, Gommer ED, Van Huffel S, Jara JL, Kostoglou K, Mahdi A, Marmarelis VZ, Mitsis GD, Muller M, Nikolic D, Nogueira RC, Payne SJ, Puppo C, Shin DC, Simpson DM, Tarumi T, Yelicich B, Zhang R, Claassen J (2019) Dynamic cerebral autoregulation reproducibility is affected by physiological variability. Front Physiol 10:865PubMedPubMedCentralCrossRef
57.
Zurück zum Zitat Sato K, Fisher JP, Seifert T, Overgaard M, Secher NH, Ogoh S (2012) Blood flow in internal carotid and vertebral arteries during orthostatic stress. Exp Physiol 97:1272–1280PubMedCrossRef Sato K, Fisher JP, Seifert T, Overgaard M, Secher NH, Ogoh S (2012) Blood flow in internal carotid and vertebral arteries during orthostatic stress. Exp Physiol 97:1272–1280PubMedCrossRef
58.
Zurück zum Zitat Schneider KT, Deckardt R (1991) The implication of upright posture on pregnancy. J Perinat Med 19:121–131PubMedCrossRef Schneider KT, Deckardt R (1991) The implication of upright posture on pregnancy. J Perinat Med 19:121–131PubMedCrossRef
59.
Zurück zum Zitat Sen S, Iyer C, Meydani SN (2014) Obesity during pregnancy alters maternal oxidant balance and micronutrient status. J Perinatol 34:105–111PubMedCrossRef Sen S, Iyer C, Meydani SN (2014) Obesity during pregnancy alters maternal oxidant balance and micronutrient status. J Perinatol 34:105–111PubMedCrossRef
60.
Zurück zum Zitat Serrador JM, Picot PA, Rutt BK, Shoemaker JK, Bondar RL (2000) MRI measures of middle cerebral artery diameter in conscious humans during simulated orthostasis. Stroke 31:1672–1678PubMedCrossRef Serrador JM, Picot PA, Rutt BK, Shoemaker JK, Bondar RL (2000) MRI measures of middle cerebral artery diameter in conscious humans during simulated orthostasis. Stroke 31:1672–1678PubMedCrossRef
61.
Zurück zum Zitat Skow RJ, Labrecque L, Rosenberger JA, Brassard P, Steinback CD (1985) Davenport MH (2022) Prenatal exercise and cardiovascular health (PEACH) study: impact of acute and chronic exercise on cerebrovascular hemodynamics and dynamic cerebral autoregulation. J Appl Physiol 132:247–260CrossRef Skow RJ, Labrecque L, Rosenberger JA, Brassard P, Steinback CD (1985) Davenport MH (2022) Prenatal exercise and cardiovascular health (PEACH) study: impact of acute and chronic exercise on cerebrovascular hemodynamics and dynamic cerebral autoregulation. J Appl Physiol 132:247–260CrossRef
62.
Zurück zum Zitat Tatu L, Moulin T, Bogousslavsky J, Duvernoy H (1996) Arterial territories of human brain: brainstem and cerebellum. Neurology 47:1125–1135PubMedCrossRef Tatu L, Moulin T, Bogousslavsky J, Duvernoy H (1996) Arterial territories of human brain: brainstem and cerebellum. Neurology 47:1125–1135PubMedCrossRef
63.
Zurück zum Zitat Tzeng YC, Willie CK, Atkinson G, Lucas SJ, Wong A, Ainslie PN (2010) Cerebrovascular regulation during transient hypotension and hypertension in humans. Hypertension 56:268–273PubMedCrossRef Tzeng YC, Willie CK, Atkinson G, Lucas SJ, Wong A, Ainslie PN (2010) Cerebrovascular regulation during transient hypotension and hypertension in humans. Hypertension 56:268–273PubMedCrossRef
64.
Zurück zum Zitat Urbano F, Roux F, Schindler J (1985) Mohsenin V (2008) Impaired cerebral autoregulation in obstructive sleep apnea. J Appl Physiol 105:1852–1857CrossRef Urbano F, Roux F, Schindler J (1985) Mohsenin V (2008) Impaired cerebral autoregulation in obstructive sleep apnea. J Appl Physiol 105:1852–1857CrossRef
65.
Zurück zum Zitat Van Lieshout JJ, Wieling W, Karemaker JM (1985) Secher NH (2003) Syncope, cerebral perfusion, and oxygenation. J Appl Physiol 94:833–848CrossRef Van Lieshout JJ, Wieling W, Karemaker JM (1985) Secher NH (2003) Syncope, cerebral perfusion, and oxygenation. J Appl Physiol 94:833–848CrossRef
66.
Zurück zum Zitat van Veen TR, Panerai RB, Haeri S, Griffioen AC, Zeeman GG, Belfort MA (2013) Cerebral autoregulation in normal pregnancy and preeclampsia. Obstet Gynecol 122:1064–1069PubMedCrossRef van Veen TR, Panerai RB, Haeri S, Griffioen AC, Zeeman GG, Belfort MA (2013) Cerebral autoregulation in normal pregnancy and preeclampsia. Obstet Gynecol 122:1064–1069PubMedCrossRef
67.
Zurück zum Zitat van Veen TR, Panerai RB, Haeri S, van den Berg PP, Zeeman GG, Belfort MA (2015) Cerebral autoregulation in pregnancies complicated by diabetes and overweight. Diab Vasc Dis Res 12:377–380PubMedCrossRef van Veen TR, Panerai RB, Haeri S, van den Berg PP, Zeeman GG, Belfort MA (2015) Cerebral autoregulation in pregnancies complicated by diabetes and overweight. Diab Vasc Dis Res 12:377–380PubMedCrossRef
68.
Zurück zum Zitat Watanabe H, Washio T, Saito S, Hirasawa A, Suzuki R, Shibata S, Brothers RM, Ogoh S (2022) Validity of transcranial Doppler ultrasonography-determined dynamic cerebral autoregulation estimated using transfer function analysis. J Clin Monit Comput 36:1711PubMedCrossRef Watanabe H, Washio T, Saito S, Hirasawa A, Suzuki R, Shibata S, Brothers RM, Ogoh S (2022) Validity of transcranial Doppler ultrasonography-determined dynamic cerebral autoregulation estimated using transfer function analysis. J Clin Monit Comput 36:1711PubMedCrossRef
69.
Zurück zum Zitat Willie CK, Colino FL, Bailey DM, Tzeng YC, Binsted G, Jones LW, Haykowsky MJ, Bellapart J, Ogoh S, Smith KJ, Smirl JD, Day TA, Lucas SJ, Eller LK, Ainslie PN (2011) Utility of transcranial Doppler ultrasound for the integrative assessment of cerebrovascular function. J Neurosci Methods 196:221–237PubMedCrossRef Willie CK, Colino FL, Bailey DM, Tzeng YC, Binsted G, Jones LW, Haykowsky MJ, Bellapart J, Ogoh S, Smith KJ, Smirl JD, Day TA, Lucas SJ, Eller LK, Ainslie PN (2011) Utility of transcranial Doppler ultrasound for the integrative assessment of cerebrovascular function. J Neurosci Methods 196:221–237PubMedCrossRef
70.
Zurück zum Zitat Zeeman GG, Hatab M, Twickler DM (2003) Maternal cerebral blood flow changes in pregnancy. Am J Obstet Gynecol 189:968–972PubMedCrossRef Zeeman GG, Hatab M, Twickler DM (2003) Maternal cerebral blood flow changes in pregnancy. Am J Obstet Gynecol 189:968–972PubMedCrossRef
71.
Zurück zum Zitat Zhang R, Zuckerman JH, Giller CA, Levine BD (1998) Transfer function analysis of dynamic cerebral autoregulation in humans. Am J Physiol 274:H233-241PubMed Zhang R, Zuckerman JH, Giller CA, Levine BD (1998) Transfer function analysis of dynamic cerebral autoregulation in humans. Am J Physiol 274:H233-241PubMed
Metadaten
Titel
Effects of posture changes on dynamic cerebral autoregulation during early pregnancy in women with obesity and/or sleep apnea
verfasst von
Takuro Washio
Sarah L. Hissen
Ryosuke Takeda
Kazumasa Manabe
John D. Akins
Belinda Sanchez
Andrew W. D’Souza
David B. Nelson
Safia Khan
Andrew R. Tomlinson
Tony G. Babb
Qi Fu
Publikationsdatum
28.04.2023
Verlag
Springer Berlin Heidelberg
Erschienen in
Clinical Autonomic Research / Ausgabe 2/2023
Print ISSN: 0959-9851
Elektronische ISSN: 1619-1560
DOI
https://doi.org/10.1007/s10286-023-00939-9

Weitere Artikel der Ausgabe 2/2023

Clinical Autonomic Research 2/2023 Zur Ausgabe