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Die Ophthalmologie

Erschienen in:

01.09.2020 | Erkrankungen der Lider | CME

Hornhautveränderungen bei Liderkrankungen

verfasst von: Prof. Dr. med. Elisabeth M. Messmer

Erschienen in: Die Ophthalmologie | Ausgabe 9/2020

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Zusammenfassung

Hornhautveränderungen bei Liderkrankungen sind häufig und können den Krankheitsverlauf erheblich komplizieren. Sie können sich als Refraktionsanomalien, Hornhautdegenerationen, Erkrankungen der Augenoberfläche, Hornhautinfiltrate, Hornhautvaskularisationen und Hornhautulzerationen bis hin zur Hornhautperforation manifestieren. Pathophysiologisch sind Druckkräfte, Exposition, Trichiasis und Distichiasis, Augenreiben, Entzündung und Infektion bedeutsam. Eine Vielzahl von Liderkrankungen geht mit Erkrankungen der Hornhaut einher wie Lidfehlstellungen, Lidtumoren, Lidinfektionen, die allergische Liddermatitis und Blepharitis, Meibomitis oder Meibom-Drüsen-Dysfunktion.

Gipson IK (2007) The ocular surface: the challenge to enable and protect vision: the Friedenwald lecture. Invest Ophthalmol Vis Sci 48(4390):4390–4398PubMedPubMedCentral

Damasceno RW, Osaki MH, Dantas PE et al (2011) Involutional entropion and ectropion of the lower eyelid: prevalence and associated risk factors in the elderly population. Ophthal Plast Reconstr Surg 27:317–320PubMed

Lane C (2012) Management of ocular surface exposure. Br J Ophthalmol 96:471–472PubMed

Detorakis ET, Ioannakis K, Kozobolis VP (2005) Corneal topography in involutional ectropion of the lower eyelid: preoperative and postoperative evaluation. Cornea 24:431–434PubMed

Jeong S, Park H, Park YG (2001) Surgical correction of congenital epiblepharon: low eyelid crease reforming technique. J Pediatr Ophthalmol Strabismus 38:356–358PubMed

Lee H, Jang S, Park M et al (2016) Effects of epiblepharon surgery on higher-order aberrations. J AAPOS 20:226–231PubMed

Heiligenhaus A, Bonsmann G, Heinz C et al (2005) Diagnostic and therapeutic recommendations for mucous membrane pemphigoid of the eye. Klin Monatsbl Augenheilkd 222:689–703PubMed

Schmidt E, Zillikens D (2011) The diagnosis and treatment of autoimmune blistering skin diseases. Dtsch Arztebl Int 108:399–405, i–iiiPubMedPubMedCentral

Ong HS, Setterfield JF, Minassian DC et al (2018) Mucous membrane pemphigoid with ocular involvement: the clinical phenotype and its relationship to direct Immunofluorescence findings. Ophthalmology 125:496–504PubMed

10.

Culbertson WW, Tseng SC (1994) Corneal disorders in floppy eyelid syndrome. Cornea 13:33–42PubMed

11.

Löw U, Schießl G, Spira-Eppig C et al (2019) Floppy eyelid syndrome : A frequently underdiagnosed entity of interdisciplinary importance. Ophthalmologe 116:1091–1102PubMed

12.

Salinas R, Puig M, Fry CL et al (2020) Floppy eyelid syndrome: a comprehensive review. Ocul Surf 18:31–39PubMed

13.

Muniesa M, Sanchez-De-La-Torre M, Huerva V et al (2014) Floppy eyelid syndrome as an indicator of the presence of glaucoma in patients with obstructive sleep apnea. J Glaucoma 23:e81–85PubMed

14.

Muniesa M, March A, Sanchez-De-La-Torre M et al (2015) Corneal biomechanical properties in floppy eyelid syndrome. Cornea 34:521–524PubMed

15.

Pihlblad MS, Schaefer DP (2013) Eyelid laxity, obesity, and obstructive sleep apnea in keratoconus. Cornea 32:1232–1236PubMed

16.

Kymionis GD, Grentzelos MA, Liakopoulos DA et al (2014) Corneal collagen crosslinking failure in a patient with floppy eyelid syndrome. J Cataract Refract Surg 40:1558–1560PubMed

17.

Imbert P, Williamson W, Leger F et al (1990) Bilateral corneal neovascularization and floppy eyelid syndrome. A case report. J Francais Ophtalmol 13:223–225

18.

Liu DT, Di Pascuale MA, Sawai J et al (2005) Tear film dynamics in floppy eyelid syndrome. Invest Ophthalmol Vis Sci 46:1188–1194PubMed

19.

Mojon DS, Goldblum D, Fleischhauer J et al (1999) Eyelid, conjunctival, and corneal findings in sleep apnea syndrome. Ophthalmology 106:1182–1185PubMed

20.

Lang F, Press UP (2017) Infantile hemangioma of the eyelid. Ophthalmologe 114:1171–1180PubMed

21.

Morrell AJ, Willshaw HE (1991) Normalisation of refractive error after steroid injection for adnexal haemangiomas. Br J Ophthalmol 75:301–305PubMedPubMedCentral

22.

Snir M, Reich U, Siegel R et al (2011) Refractive and structural changes in infantile periocular capillary haemangioma treated with propranolol. Eye 25:1627–1634PubMedPubMedCentral

23.

Ormond AW (1921) Notes on three cases of acquired astigmatism associated with meibomian cysts. Br J Ophthalmol 5:117–118PubMedPubMedCentral

24.

Bagheri A, Hasani HR, Karimian F et al (2009) Effect of chalazion excision on refractive error and corneal topography. Eur J Ophthalmol 19:521–526PubMed

25.

Fukuoka S, Arita R, Shirakawa R et al (2017) Changes in meibomian gland morphology and ocular higher-order aberrations in eyes with chalazion. Clin Ophthalmol 11:1031–1038PubMedPubMedCentral

26.

Jin KW, Shin YJ, Hyon JY (2017) Effects of chalazia on corneal astigmatism : large-sized chalazia in middle upper eyelids compress the cornea and induce the corneal astigmatism. BMC Ophthalmol 17:36PubMedPubMedCentral

27.

Sabermoghaddam AA, Zarei-Ghanavati S, Abrishami M (2013) Effects of chalazion excision on ocular aberrations. Cornea 32:757–760PubMed

28.

Geerling G (2019) Neurotrophic keratopathy-Underdiagnosed and incurable? Ophthalmologe 116:108PubMed

29.

Liesegang TJ (2008) Herpes zoster ophthalmicus natural history, risk factors, clinical presentation, and morbidity. Ophthalmology 115:S3–S12PubMed

30.

Liesegang TJ (2004) Herpes zoster virus infection. Curr Opin Ophthalmol 15:531–536PubMed

31.

Roesel M, Heiligenhaus A, Messmer EM (2010) Clinical presentation of zoster ophthalmicus. Klin Monatsbl Augenheilkd 227:370–374PubMed

32.

Werner RN, Steinhorst NI, Nast A et al (2017) Diagnostics and management of herpes zoster ophthalmicus. Ophthalmologe 114:959–972PubMed

33.

Butsch F, Greger D, Butsch C et al (2017) Die prognostische Bedeutung des Hutchinson-Zeichens für eine okuläre Beteiliung bei Herpes zoster ophtalmicus. J Dtsch Dermatol Ges 15:563–564PubMed

34.

Cobo M, Foulks GN, Liesegang T et al (1987) Observations on the natural history of herpes zoster ophthalmicus. Curr Eye Res 6:195–199PubMed

35.

Gross GE, Eisert L, Doerr HW et al (2020) S2k guidelines for the diagnosis and treatment of herpes zoster and postherpetic neuralgia. J Dtsch Dermatol Ges 18:55–78PubMed

36.

Tran KD, Falcone MM, Choi DS et al (2016) Epidemiology of herpes zoster ophthalmicus: recurrence and chronicity. Ophthalmology 123:1469–1475PubMedPubMedCentral

37.

Siedler A, Koch J, Garbe E et al (2019) Background paper to the decision to recommend the vaccination with the inactivated herpes zoster subunit vaccine: Statement of the German Standing Committee on Vaccination (STIKO) at the Robert Koch Institute. Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz 62:352–376PubMed

38.

Furrer P, Mayer JM, Gurny R (2002) Ocular tolerance of preservatives and alternatives. Eur J Pharm Biopharm 53:263–280PubMed

39.

Hong J, Bielory L (2009) Allergy to ophthalmic preservatives. Curr Opin Allergy Clin Immunol 9:447–453PubMed

40.

Kalavala M, Statham BN (2006) Allergic contact dermatitis from timolol and dorzolamide eye drops. Contact Derm 54:345PubMed

41.

Corazza M, Levratti A, Zampino MR et al (2002) Conventional patch tests are poor detectors of contact allergy from ophthalmic products. Contact Derm 46:298–299PubMed

42.

Corazza M, Masieri LT, Virgili A (2005) Doubtful value of patch testing for suspected contact allergy to ophthalmic products. Acta Derm Venereol 85:70–71PubMed

43.

Fauquert JL, Jedrzejczak-Czechowicz M, Rondon C et al (2017) Conjunctival allergen provocation test : guidelines for daily practice. Allergy 72:43–54PubMed

44.

Messmer EM, May CA, Stefani FH et al (2002) Toxic eosinophil granule protein deposition in corneal ulcerations and scars associated with atopic keratoconjunctivitis. Am J Ophthalmol 134:816–821PubMed

45.

Borkar DS, Gonzales JA, Tham VM et al (2014) Association between atopy and herpetic eye disease: results from the pacific ocular inflammation study. JAMA Ophthalmol 132:326–331PubMed

46.

Kallen C, Reinhard T, Schilgen G et al (2003) Atopic keratoconjunctivitis: probably a risk factor for the development of conjuntival carcinoma. Ophthalmologe 100:808–814PubMed

47.

Shah A, Espana EM, Singh AD (2017) Ocular surface squamous neoplasia associated with atopic keratoconjunctivitis. Ocul Oncol Pathol 3:22–27PubMed

48.

Bawazeer AM, Hodge WG, Lorimer B (2000) Atopy and keratoconus: a multivariate analysis. Br J Ophthalmol 84:834–836PubMedPubMedCentral

49.

Hashemi H, Heydarian S, Hooshmand E et al (2020) The prevalence and risk factors for keratoconus: a systematic review and meta-analysis. Cornea 39:263–270PubMed

50.

Weed KH, Macewen CJ, Giles T et al (2008) The Dundee University Scottish Keratoconus study: demographics, corneal signs, associated diseases, and eye rubbing. Eye 22:534–541PubMed

51.

Ebihara N, Funaki T, Matsuda H et al (2008) Corneal abnormalities in the NC/Nga mouse: an atopic dermatitis model. Cornea 27:923–929PubMed

52.

Jeon HS, Choi M, Byun SJ et al (2018) Atopic dermatitis is not a risk factor for keratoconus: a population-based cohort study. J Am Acad Dermatol 79:160–162PubMed

53.

Thyssen JP, De Bruin-Weller MS, Paller AS et al (2019) Conjunctivitis in atopic dermatitis patients with and without dupilumab therapy—international eczema council survey and opinion. J Eur Acad Dermatol Venereol 33:1224–1231PubMedPubMedCentral

54.

Wohlrab J, Wollenberg A, Reimann H et al (2019) Interdisciplinary recommendations for action in dupilumab-related inflammatory eye diseases. Hautarzt 70:64–67PubMed

55.

Gallo RL, Granstein RD, Kang S et al (2018) Standard classification and pathophysiology of rosacea: The 2017 update by the National Rosacea Society Expert Committee. J Am Acad Dermatol 78:148–155PubMed

56.

Reinholz M, Tietze JK, Kilian K et al (2013) Rosacea – S1 guideline. J Dtsch Dermatol Ges 11:768–780; 768–779PubMed

57.

Donaldson KE, Karp CL, Dunbar MT (2007) Evaluation and treatment of children with ocular rosacea. Cornea 26:42–46PubMed

58.

Schaller M, Almeida LM, Bewley A et al (2017) Rosacea treatment update: recommendations from the global ROSacea COnsensus (ROSCO) panel. Br J Dermatol 176:465–471PubMed

59.

Foulks GN, Borchman D, Yappert M et al (2013) Topical azithromycin and oral doxycycline therapy of meibomian gland dysfunction: a comparative clinical and spectroscopic pilot study. Cornea 32:44–53PubMedPubMedCentral

60.

Zandian M, Rahimian N, Soheilifar S (2016) Comparison of therapeutic effects of topical azithromycin solution and systemic doxycycline on posterior blepharitis. Int J Ophthalmol 9:1016–1019PubMedPubMedCentral

61.

Wladis EJ, Adam AP (2018) Treatment of ocular rosacea. Surv Ophthalmol 63:340–346PubMed

62.

Akhyani M, Ehsani AH, Ghiasi M et al (2008) Comparison of efficacy of azithromycin vs. doxycycline in the treatment of rosacea: a randomized open clinical trial. Int J Dermatol 47:284–288PubMed

Titel: Hornhautveränderungen bei Liderkrankungen
verfasst von: Prof. Dr. med. Elisabeth M. Messmer
Publikationsdatum: 01.09.2020
Verlag: Springer Medizin
Schlagwörter: Erkrankungen der Lider
Konjunktivitis
Refraktionsfehler
Rosazea
Schleimhautpemphigoid
Herpes zoster
Erschienen in: Die Ophthalmologie / Ausgabe 9/2020
Print ISSN: 2731-720X
Elektronische ISSN: 2731-7218
DOI: https://doi.org/10.1007/s00347-020-01219-x

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Zusammenfassung

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