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16.06.2022 | Computed Tomography

First-generation clinical dual-source photon-counting CT: ultra-low-dose quantitative spectral imaging

verfasst von: Leening P. Liu, Nadav Shapira, Andrew A. Chen, Russell T. Shinohara, Pooyan Sahbaee, Mitchell Schnall, Harold I. Litt, Peter B. Noël

Erschienen in: European Radiology | Ausgabe 12/2022

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Abstract

Objective

Evaluation of image characteristics at ultra-low radiation dose levels of a first-generation dual-source photon-counting computed tomography (PCCT) compared to a dual-source dual-energy CT (DECT) scanner.

Methods

A multi-energy CT phantom was imaged with and without an extension ring on both scanners over a range of radiation dose levels (CTDI_vol 0.4–15.0 mGy). Scans were performed in different modes of acquisition for PCCT with 120 kVp and DECT with 70/Sn150 kVp and 100/Sn150 kVp. Various tissue inserts were used to characterize the precision and repeatability of Hounsfield units (HUs) on virtual mono-energetic images between 40 and 190 keV. Image noise was additionally investigated at an ultra-low radiation dose to illustrate PCCT’s ability to remove electronic background noise.

Results

Our results demonstrate the high precision of HU measurements for a wide range of inserts and radiation exposure levels with PCCT. We report high performance for both scanners across a wide range of radiation exposure levels, with PCCT outperforming at low exposures compared to DECT. PCCT scans at the lowest radiation exposures illustrate significant reduction in electronic background noise, with a mean percent reduction of 74% (p value ~ 10⁻⁸) compared to DECT 70/Sn150 kVp and 60% (p value ~ 10⁻⁶) compared to DECT 100/Sn150 kVp.

Conclusions

This paper reports the first experiences with a clinical dual-source PCCT. PCCT provides reliable HUs without disruption from electronic background noise for a wide range of dose values. Diagnostic benefits are not only for quantification at an ultra-low dose but also for imaging of obese patients.

Key Points

PCCT scanners provide precise and reliable Hounsfield units at ultra-low dose levels.
The influence of electronic background noise can be removed at ultra-low-dose acquisitions with PCCT.
Both spectral platforms have high performance along a wide range of radiation exposure levels, with PCCT outperforming at low radiation exposures.

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Titel: First-generation clinical dual-source photon-counting CT: ultra-low-dose quantitative spectral imaging
verfasst von: Leening P. Liu
Nadav Shapira
Andrew A. Chen
Russell T. Shinohara
Pooyan Sahbaee
Mitchell Schnall
Harold I. Litt
Peter B. Noël
Publikationsdatum: 16.06.2022
Verlag: Springer Berlin Heidelberg
Erschienen in: European Radiology / Ausgabe 12/2022
Print ISSN: 0938-7994
Elektronische ISSN: 1432-1084
DOI: https://doi.org/10.1007/s00330-022-08933-x

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First-generation clinical dual-source photon-counting CT: ultra-low-dose quantitative spectral imaging

Abstract

Objective

Methods

Results

Conclusions

Key Points

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