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Erschienen in: Somnologie 2/2017

22.05.2017 | Hypoxämie | CME

Schlafstörungen bei Lungenkrankheiten

verfasst von: Prof. Dr. Richard Schulz, MHBA, Dr. Jörg Heitmann, Prof. Dr. Dr. Tim Oliver Hirche

Erschienen in: Somnologie | Ausgabe 2/2017

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Zusammenfassung

Lungenkrankheiten können den normalen, gesunden Schlaf in vielfältiger Weise beeinträchtigen. Einschränkungen der Lungenfunktion bewirken eine Störung des Gasaustausches, die sich in Form von schlafbezogenen Hypoxämien und Hypoventilationen äußern können. Der Schlaf kann bei den betroffenen Patienten aber auch durch andere Faktoren gestört werden, wie z. B. durch nächtlichen Husten oder Dyspnoe. Schließlich gibt es bei mehreren Lungenkrankheiten komplexe und z. T. wechselseitige Beziehungen zur Schlafapnoe. Die Schlafstörungen bei Lungenkrankheiten äußern sich klinisch u. a. in schlechter Schlafqualität, Tagesmüdigkeit und -schläfrigkeit sowie reduzierter Lebensqualität. Die apparative Diagnostik umfasst Pulsoxymetrie, Kapnometrie und Poly(somno)graphie. Therapeutisch stehen neben der Behandlung der pulmonalen Grunderkrankung die O2-Gabe, die nichtinvasive Ventilationstherapie sowie die CPAP-Therapie („continuous positive airway pressure“) im Vordergrund.
Literatur
1.
Zurück zum Zitat Sowho M, Amatoury J, Kirkness JP, Patil SP (2014) Sleep and respiratory physiology in adults. Clin Chest Med 35:469–481CrossRefPubMed Sowho M, Amatoury J, Kirkness JP, Patil SP (2014) Sleep and respiratory physiology in adults. Clin Chest Med 35:469–481CrossRefPubMed
2.
Zurück zum Zitat Sanz de Burgoa V, Rejas J, Ojeda P, Investigators of the Coste Asma study (2016) Self-perceived sleep quality and quantity in adults with asthma: findings from the CosteAsma study. J Investig Allergol Clin Immunol 26(4):256–262CrossRefPubMed Sanz de Burgoa V, Rejas J, Ojeda P, Investigators of the Coste Asma study (2016) Self-perceived sleep quality and quantity in adults with asthma: findings from the CosteAsma study. J Investig Allergol Clin Immunol 26(4):256–262CrossRefPubMed
3.
Zurück zum Zitat Luyster FS, Strollo PJ Jr, Holguin F, Castro M, Dunican EM, Fahy J, Gaston B, Israel E, Jarjour NN, Mauger DT, Moore WC, Wenzel SE (2016) Association between insomnia and asthma burden in the Severe Asthma Research Program (SARP) III. Chest 150(6):1242–1250CrossRefPubMed Luyster FS, Strollo PJ Jr, Holguin F, Castro M, Dunican EM, Fahy J, Gaston B, Israel E, Jarjour NN, Mauger DT, Moore WC, Wenzel SE (2016) Association between insomnia and asthma burden in the Severe Asthma Research Program (SARP) III. Chest 150(6):1242–1250CrossRefPubMed
4.
5.
Zurück zum Zitat Gross V, Reinke C, Dette F, Koch R, Vasilescu D, Penzel T, Köhler U (2007) Mobile nocturnal long-term monitoring of wheezing and cough. Biomed Tech (Berl) 52:73–76CrossRef Gross V, Reinke C, Dette F, Koch R, Vasilescu D, Penzel T, Köhler U (2007) Mobile nocturnal long-term monitoring of wheezing and cough. Biomed Tech (Berl) 52:73–76CrossRef
6.
Zurück zum Zitat Teodorescu M, Barnet JH, Hagen EW, Palta M, Young TB, Peppard PE (2015) Association between asthma and risk of developing obstructive sleep apnea. JAMA 313:156–164CrossRefPubMedPubMedCentral Teodorescu M, Barnet JH, Hagen EW, Palta M, Young TB, Peppard PE (2015) Association between asthma and risk of developing obstructive sleep apnea. JAMA 313:156–164CrossRefPubMedPubMedCentral
7.
8.
Zurück zum Zitat Serrano-Pariente J, Plaza V, Soriano JB, Mayos M, López-Viña A, Picado C, Vigil L, CPASMA Trial Group (2016) Asthma outcomes improve with continuous positive airway pressure for obstructive sleep apnea. Allergy. doi:10.1111/all.13070 PubMedPubMedCentral Serrano-Pariente J, Plaza V, Soriano JB, Mayos M, López-Viña A, Picado C, Vigil L, CPASMA Trial Group (2016) Asthma outcomes improve with continuous positive airway pressure for obstructive sleep apnea. Allergy. doi:10.​1111/​all.​13070 PubMedPubMedCentral
9.
Zurück zum Zitat Kauppi P, Bachour P, Maasilta P, Bachour A (2016) Long-term CPAP treatment improves asthma control in patients with asthma and obstructive sleep apnoea. Sleep Breath 20(4):1217–1224CrossRefPubMed Kauppi P, Bachour P, Maasilta P, Bachour A (2016) Long-term CPAP treatment improves asthma control in patients with asthma and obstructive sleep apnoea. Sleep Breath 20(4):1217–1224CrossRefPubMed
10.
Zurück zum Zitat Klink M, Quan SF (1987) Prevalence of reported sleep disturbances in a general adult population and their relationship to obstructive airways diseases. Chest 91:540–546CrossRefPubMed Klink M, Quan SF (1987) Prevalence of reported sleep disturbances in a general adult population and their relationship to obstructive airways diseases. Chest 91:540–546CrossRefPubMed
11.
Zurück zum Zitat Fletcher EC, Miller J, Divine GW, Fletcher JG, Miller T (1987) Nocturnal oxyhemoglobin desaturation in COPD patients with arterial oxygen tensions above 60 mm Hg. Chest 92:604–608CrossRefPubMed Fletcher EC, Miller J, Divine GW, Fletcher JG, Miller T (1987) Nocturnal oxyhemoglobin desaturation in COPD patients with arterial oxygen tensions above 60 mm Hg. Chest 92:604–608CrossRefPubMed
12.
Zurück zum Zitat Becker HF, Piper AJ, Flynn WE, McNamara SG, Grunstein RR, Peter JH, Sullivan CE (1999) Breathing during sleep in patients with nocturnal desaturation. Am J Respir Crit Care Med 159:112–118CrossRefPubMed Becker HF, Piper AJ, Flynn WE, McNamara SG, Grunstein RR, Peter JH, Sullivan CE (1999) Breathing during sleep in patients with nocturnal desaturation. Am J Respir Crit Care Med 159:112–118CrossRefPubMed
13.
Zurück zum Zitat Mulloy E, McNicholas WT (1996) Ventilation and gas exchange during sleep and exercise in severe COPD. Chest 109:387–394CrossRefPubMed Mulloy E, McNicholas WT (1996) Ventilation and gas exchange during sleep and exercise in severe COPD. Chest 109:387–394CrossRefPubMed
14.
Zurück zum Zitat Köhnlein T, Windisch W, Köhler D, Drabik A, Geiseler J, Hartl S, Karg O, Laier-Groeneveld G, Nava S, Schönhofer B, Schucher B, Wegscheider K, Criée CP, Welte T (2014) Non-invasive positive pressure ventilation for the treatment of severe stable chronic obstructive pulmonary disease: a prospective, multicentre, randomised, controlled clinical trial. Lancet Respir Med 2(9):698–705CrossRefPubMed Köhnlein T, Windisch W, Köhler D, Drabik A, Geiseler J, Hartl S, Karg O, Laier-Groeneveld G, Nava S, Schönhofer B, Schucher B, Wegscheider K, Criée CP, Welte T (2014) Non-invasive positive pressure ventilation for the treatment of severe stable chronic obstructive pulmonary disease: a prospective, multicentre, randomised, controlled clinical trial. Lancet Respir Med 2(9):698–705CrossRefPubMed
15.
Zurück zum Zitat Chaouat A, Weitzenblum E, Krieger J et al (1995) Association of chronic obstructive pulmonary disease and sleep apnea syndrome. Am J Respir Crit Care Med 151:82–86CrossRefPubMed Chaouat A, Weitzenblum E, Krieger J et al (1995) Association of chronic obstructive pulmonary disease and sleep apnea syndrome. Am J Respir Crit Care Med 151:82–86CrossRefPubMed
16.
Zurück zum Zitat Marin JM, Soriano JB, Carrizo SJ, Boldova A, Celli BR (2010) Outcomes in patients with chronic obstructive pulmonary disease and obstructive sleep apnea: the overlap syndrome. Am J Respir Crit Care Med 182:325–331CrossRefPubMed Marin JM, Soriano JB, Carrizo SJ, Boldova A, Celli BR (2010) Outcomes in patients with chronic obstructive pulmonary disease and obstructive sleep apnea: the overlap syndrome. Am J Respir Crit Care Med 182:325–331CrossRefPubMed
17.
Zurück zum Zitat Clark M, Cooper B, Singh S et al (2001) A survey of nocturnal hypoxaemia and health related quality of life in patients with cryptogenic fibrosing alveolitis. Thorax 56:482–486CrossRefPubMedPubMedCentral Clark M, Cooper B, Singh S et al (2001) A survey of nocturnal hypoxaemia and health related quality of life in patients with cryptogenic fibrosing alveolitis. Thorax 56:482–486CrossRefPubMedPubMedCentral
18.
Zurück zum Zitat Krishnan V, McCormack MC, Mathai SC, Agarwal S, Richardson B, Horton MR et al (2008) Sleep quality and health-related quality of life in idiopathic pulmonary fibrosis. Chest 134:693–698CrossRefPubMed Krishnan V, McCormack MC, Mathai SC, Agarwal S, Richardson B, Horton MR et al (2008) Sleep quality and health-related quality of life in idiopathic pulmonary fibrosis. Chest 134:693–698CrossRefPubMed
19.
Zurück zum Zitat Bye P, Issa F, Berthon-Jones M et al (1984) Studies of oxygenation during sleep in patients with interstitial lung disease. Am Rev Respir Dis 129:27–32PubMed Bye P, Issa F, Berthon-Jones M et al (1984) Studies of oxygenation during sleep in patients with interstitial lung disease. Am Rev Respir Dis 129:27–32PubMed
20.
Zurück zum Zitat Kolilekas L, Manali E, Vlami KA et al (2013) Sleep oxygen desaturation predicts survival in idiopathic pulmonary fibrosis. J Clin Sleep Med 9:593–601PubMedPubMedCentral Kolilekas L, Manali E, Vlami KA et al (2013) Sleep oxygen desaturation predicts survival in idiopathic pulmonary fibrosis. J Clin Sleep Med 9:593–601PubMedPubMedCentral
21.
Zurück zum Zitat McNicholas W, Coffey M, Fitzgerald M (1986) Ventilation and gas exchange during sleep in patients with interstitial lung disease. Thorax 41:777–782CrossRefPubMedPubMedCentral McNicholas W, Coffey M, Fitzgerald M (1986) Ventilation and gas exchange during sleep in patients with interstitial lung disease. Thorax 41:777–782CrossRefPubMedPubMedCentral
22.
Zurück zum Zitat Mermigkis C, Chapman J, Golish J et al (2007) Sleep-related breathing disorders in patients with idiopathic pulmonary fibrosis. Lung 185:173–178CrossRefPubMed Mermigkis C, Chapman J, Golish J et al (2007) Sleep-related breathing disorders in patients with idiopathic pulmonary fibrosis. Lung 185:173–178CrossRefPubMed
23.
24.
Zurück zum Zitat Mermigkis C, Stagaki E, Tryfon S et al (2010) How common is sleep-disordered breathing in patients with idiopathic pulmonary fibrosis? Sleep Breath 14:387–390CrossRefPubMed Mermigkis C, Stagaki E, Tryfon S et al (2010) How common is sleep-disordered breathing in patients with idiopathic pulmonary fibrosis? Sleep Breath 14:387–390CrossRefPubMed
25.
Zurück zum Zitat Pihtili A, Bingol Z, Kiyan E et al (2013) Obstructive sleep apnea is common in patients with interstitial lung disease. Sleep Breath 17:1281–1288CrossRefPubMed Pihtili A, Bingol Z, Kiyan E et al (2013) Obstructive sleep apnea is common in patients with interstitial lung disease. Sleep Breath 17:1281–1288CrossRefPubMed
26.
Zurück zum Zitat Aronson RM, Carley DW, Onal E (1991) Upper airway muscle activity and the thoracic volume dependence of upper airway resistance. J Appl Physiol 70:430–438PubMed Aronson RM, Carley DW, Onal E (1991) Upper airway muscle activity and the thoracic volume dependence of upper airway resistance. J Appl Physiol 70:430–438PubMed
27.
Zurück zum Zitat Milross MA, Piper AJ, Norman M, Dobbin CJ, Grunstein RR, Sullivan CE, Bye PT (2002) Subjective sleep quality in cystic fibrosis. Sleep Med 3:205–212CrossRefPubMed Milross MA, Piper AJ, Norman M, Dobbin CJ, Grunstein RR, Sullivan CE, Bye PT (2002) Subjective sleep quality in cystic fibrosis. Sleep Med 3:205–212CrossRefPubMed
28.
Zurück zum Zitat Bouka A, Tiede H, Liebich L, Dumitrascu R, Hecker C, Reichenberger F, Mayer K, Seeger W, Schulz R (2012) Quality of life in clinically stable adult cystic fibrosis out-patients: associations with daytime sleepiness and sleep quality. Respir Med 106:1244–1249CrossRefPubMed Bouka A, Tiede H, Liebich L, Dumitrascu R, Hecker C, Reichenberger F, Mayer K, Seeger W, Schulz R (2012) Quality of life in clinically stable adult cystic fibrosis out-patients: associations with daytime sleepiness and sleep quality. Respir Med 106:1244–1249CrossRefPubMed
29.
Zurück zum Zitat Milross MA, Piper AJ, Dobbin CJ, Bye PT, Grunstein RR (2004) Sleep disordered breathing in cystic fibrosis. Sleep Med Rev 8:295–308CrossRefPubMed Milross MA, Piper AJ, Dobbin CJ, Bye PT, Grunstein RR (2004) Sleep disordered breathing in cystic fibrosis. Sleep Med Rev 8:295–308CrossRefPubMed
30.
Zurück zum Zitat Spicuzza L, Sciuto C, Leonardi S, La Rosa M (2012) Early occurrence of obstructive sleep apnea in infants and children with cystic fibrosis. Arch Pediatr Adolesc Med 166:1165–1169CrossRefPubMed Spicuzza L, Sciuto C, Leonardi S, La Rosa M (2012) Early occurrence of obstructive sleep apnea in infants and children with cystic fibrosis. Arch Pediatr Adolesc Med 166:1165–1169CrossRefPubMed
31.
Zurück zum Zitat van der Giessen L, Loeve M, de Jongste J, Hop W, Tiddens H (2009) Nocturnal cough in children with stable cystic fibrosis. Pediatr Pulmonol 44:859–865CrossRefPubMed van der Giessen L, Loeve M, de Jongste J, Hop W, Tiddens H (2009) Nocturnal cough in children with stable cystic fibrosis. Pediatr Pulmonol 44:859–865CrossRefPubMed
32.
Zurück zum Zitat Flume PA, Ciolino J, Gray S, Lester MK (2009) Patient-reported pain and impaired sleep quality in adult patients with cystic fibrosis. J Cyst Fibros 8:321–325CrossRefPubMed Flume PA, Ciolino J, Gray S, Lester MK (2009) Patient-reported pain and impaired sleep quality in adult patients with cystic fibrosis. J Cyst Fibros 8:321–325CrossRefPubMed
33.
Zurück zum Zitat Rich S, Dantzker DR, Ayres SM, Bergofsky EH, Brundage BH, Detre KM et al (1987) Primary pulmonary hypertension. A national prospective study. Ann Intern Med 107:216–223CrossRefPubMed Rich S, Dantzker DR, Ayres SM, Bergofsky EH, Brundage BH, Detre KM et al (1987) Primary pulmonary hypertension. A national prospective study. Ann Intern Med 107:216–223CrossRefPubMed
34.
Zurück zum Zitat Batal O, Khatib OF, Bair N, Aboussouan LS, Minai OA (2011) Sleep quality, depression and quality of life in patients with pulmonary hypertension. Lung 189:141–149CrossRefPubMed Batal O, Khatib OF, Bair N, Aboussouan LS, Minai OA (2011) Sleep quality, depression and quality of life in patients with pulmonary hypertension. Lung 189:141–149CrossRefPubMed
35.
Zurück zum Zitat Tiede H, Rorzyczka J, Dumitrascu R, Belly M, Reichenberger F, Ghofrani HA, Seeger W, Heitmann J, Schulz R (2015) Poor sleep quality is associated with exercise limitation in precapillary pulmonary hypertension. BMC Pulm Med 15:11CrossRefPubMedPubMedCentral Tiede H, Rorzyczka J, Dumitrascu R, Belly M, Reichenberger F, Ghofrani HA, Seeger W, Heitmann J, Schulz R (2015) Poor sleep quality is associated with exercise limitation in precapillary pulmonary hypertension. BMC Pulm Med 15:11CrossRefPubMedPubMedCentral
36.
Zurück zum Zitat Minai OA, Pandya CM, Golish JA et al (2007) Predictors of nocturnal oxygen desaturation in pulmonary arterial hypertension. Chest 131:109–117CrossRefPubMed Minai OA, Pandya CM, Golish JA et al (2007) Predictors of nocturnal oxygen desaturation in pulmonary arterial hypertension. Chest 131:109–117CrossRefPubMed
37.
Zurück zum Zitat Sajkov D, McEvoy RD (2009) Obstructive sleep apnea and pulmonary hypertension. Prog Cardiovasc Dis 51:363–370CrossRefPubMed Sajkov D, McEvoy RD (2009) Obstructive sleep apnea and pulmonary hypertension. Prog Cardiovasc Dis 51:363–370CrossRefPubMed
38.
Zurück zum Zitat Sajkov D, Wang T, Saunders NA et al (1999) Daytime pulmonary hemodynamics in patients with obstructive sleep apnea without lung disease. Am J Respir Crit Care Med 159:15218–15226CrossRef Sajkov D, Wang T, Saunders NA et al (1999) Daytime pulmonary hemodynamics in patients with obstructive sleep apnea without lung disease. Am J Respir Crit Care Med 159:15218–15226CrossRef
39.
Zurück zum Zitat Sun X, Luo J, Xiao Y (2014) Continuous positive airway pressure is associated with a decrease in pulmonary artery pressure in patients with obstructive sleep apnoea: a meta-analysis. Respirology 19(5):670–674CrossRefPubMed Sun X, Luo J, Xiao Y (2014) Continuous positive airway pressure is associated with a decrease in pulmonary artery pressure in patients with obstructive sleep apnoea: a meta-analysis. Respirology 19(5):670–674CrossRefPubMed
40.
Zurück zum Zitat Arzt M, Luigart R, Schum C, Lüthje L, Stein A, Koper I, Hecker C, Dumitrascu R, Schulz R (2012) Sleep-disordered breathing in deep vein thrombosis and acute pulmonary embolism. Eur Respir J 40:919–924CrossRefPubMed Arzt M, Luigart R, Schum C, Lüthje L, Stein A, Koper I, Hecker C, Dumitrascu R, Schulz R (2012) Sleep-disordered breathing in deep vein thrombosis and acute pulmonary embolism. Eur Respir J 40:919–924CrossRefPubMed
41.
Zurück zum Zitat Peng YH, Liao WC, Chung WS, Muo CH, Chu CC, Liu CJ, Kao CH (2014) Association between obstructive sleep apnea and deep vein thrombosis/pulmonary embolism: a population-based retrospective cohort study. Thromb Res 134(2):340–345CrossRefPubMed Peng YH, Liao WC, Chung WS, Muo CH, Chu CC, Liu CJ, Kao CH (2014) Association between obstructive sleep apnea and deep vein thrombosis/pulmonary embolism: a population-based retrospective cohort study. Thromb Res 134(2):340–345CrossRefPubMed
42.
Zurück zum Zitat Alonso-Fernández A, Suquia AG, de la Peña M, Casitas R, Pierola J, Barceló A, Soriano JB, Fernández-Capitán C, Martinez-Ceron E, Carrera M, García-Río F (2016) OSA is a risk factor for recurrent VTE. Chest 150(6):1291–1301CrossRefPubMed Alonso-Fernández A, Suquia AG, de la Peña M, Casitas R, Pierola J, Barceló A, Soriano JB, Fernández-Capitán C, Martinez-Ceron E, Carrera M, García-Río F (2016) OSA is a risk factor for recurrent VTE. Chest 150(6):1291–1301CrossRefPubMed
43.
Zurück zum Zitat Berghaus TM, Witkowska A, Wagner T, Faul C, Schwaiblmair M, von Scheidt W (2016) Obstructive sleep apnea might trigger acute pulmonary embolism: results from a cohort study. Clin Res Cardiol 105(11):938–943CrossRefPubMed Berghaus TM, Witkowska A, Wagner T, Faul C, Schwaiblmair M, von Scheidt W (2016) Obstructive sleep apnea might trigger acute pulmonary embolism: results from a cohort study. Clin Res Cardiol 105(11):938–943CrossRefPubMed
44.
Zurück zum Zitat Dumitrascu R, Tiede H, Eckermann J, Mayer K, Reichenberger F, Ghofrani HA, Seeger W, Heitmann J, Schulz R (2013) Sleep apnea in precapillary pulmonary hypertension. Sleep Med 14:247–251CrossRefPubMed Dumitrascu R, Tiede H, Eckermann J, Mayer K, Reichenberger F, Ghofrani HA, Seeger W, Heitmann J, Schulz R (2013) Sleep apnea in precapillary pulmonary hypertension. Sleep Med 14:247–251CrossRefPubMed
45.
Zurück zum Zitat Pitsiou GG, Boutou AK, Nakou C et al (2010) Resolution of nocturnal periodic breathing in pulmonary hypertension after optimal treatment. Ther Adv Respir Dis 4:249–251CrossRefPubMed Pitsiou GG, Boutou AK, Nakou C et al (2010) Resolution of nocturnal periodic breathing in pulmonary hypertension after optimal treatment. Ther Adv Respir Dis 4:249–251CrossRefPubMed
46.
Zurück zum Zitat Held M, Meintz S, Baron S, Roth C, Wilkens H, Schäfers HJ, Jany B (2013) Surgical cure of central sleep apnea? Am J Respir Crit Care Med 188:395–396CrossRefPubMed Held M, Meintz S, Baron S, Roth C, Wilkens H, Schäfers HJ, Jany B (2013) Surgical cure of central sleep apnea? Am J Respir Crit Care Med 188:395–396CrossRefPubMed
47.
Zurück zum Zitat Schulz R, Fegbeutel C, Olschewski H, Rose F, Schäfers HJ, Seeger W (2004) Reversal of nocturnal periodic breathing in primary pulmonary hypertension after lung transplantation. Chest 125:344–347CrossRefPubMed Schulz R, Fegbeutel C, Olschewski H, Rose F, Schäfers HJ, Seeger W (2004) Reversal of nocturnal periodic breathing in primary pulmonary hypertension after lung transplantation. Chest 125:344–347CrossRefPubMed
48.
Zurück zum Zitat Schulz R, Baseler G, Ghofrani HA, Grimminger F, Olschewski H, Seeger W (2002) Nocturnal periodic breathing in primary pulmonary hypertension. Eur Respir J 19:658–663CrossRefPubMed Schulz R, Baseler G, Ghofrani HA, Grimminger F, Olschewski H, Seeger W (2002) Nocturnal periodic breathing in primary pulmonary hypertension. Eur Respir J 19:658–663CrossRefPubMed
49.
Zurück zum Zitat Solin P, Bergin P, Richardson M, Kaye DM, Walters EH, Naughton MT (1999) Influence of pulmonary capillary wedge pressure on central apnea in heart failure. Circulation 99:1574–1579CrossRefPubMed Solin P, Bergin P, Richardson M, Kaye DM, Walters EH, Naughton MT (1999) Influence of pulmonary capillary wedge pressure on central apnea in heart failure. Circulation 99:1574–1579CrossRefPubMed
50.
Zurück zum Zitat Chaudhary BA, Ferguson DS, Speir WA Jr. (1982) Pulmonary edema as a presenting feature of sleep apnea syndrome. Chest 82:122–124CrossRefPubMed Chaudhary BA, Ferguson DS, Speir WA Jr. (1982) Pulmonary edema as a presenting feature of sleep apnea syndrome. Chest 82:122–124CrossRefPubMed
51.
Zurück zum Zitat Le Guen Y, Gagnadoux F, Hureaux J, Jeanfaivre T, Meslier N, Racineux JL, Urban T (2007) Sleep disturbances and impaired daytime functioning in outpatients with newly diagnosed lung cancer. Lung Cancer 58(1):139–143CrossRefPubMed Le Guen Y, Gagnadoux F, Hureaux J, Jeanfaivre T, Meslier N, Racineux JL, Urban T (2007) Sleep disturbances and impaired daytime functioning in outpatients with newly diagnosed lung cancer. Lung Cancer 58(1):139–143CrossRefPubMed
52.
Zurück zum Zitat Ito M, Tanaka J, Kubota K, Sato H, Takahashi M, Tanaka H, Ohdaira T, Yoshizawa H, Muramatsu Y, Satoh M, Suzuki E, Arakawa M, Gejyo F (2000) Obstructive sleep apnea syndrome in a patient with superior vena cava syndrome caused by lung cancer. Nihon Kokyuki Gakkai Zasshi 38(6):471–475PubMed Ito M, Tanaka J, Kubota K, Sato H, Takahashi M, Tanaka H, Ohdaira T, Yoshizawa H, Muramatsu Y, Satoh M, Suzuki E, Arakawa M, Gejyo F (2000) Obstructive sleep apnea syndrome in a patient with superior vena cava syndrome caused by lung cancer. Nihon Kokyuki Gakkai Zasshi 38(6):471–475PubMed
53.
Zurück zum Zitat Ursavaş A, Karadag M, Burgazlioglu B, Coşkun F, Ceylan E, Onart S, Gozu RO (2007) Relief from sleep apnea after radiation and chemotherapy. Clin Lung Cancer 8(8):502–503CrossRefPubMed Ursavaş A, Karadag M, Burgazlioglu B, Coşkun F, Ceylan E, Onart S, Gozu RO (2007) Relief from sleep apnea after radiation and chemotherapy. Clin Lung Cancer 8(8):502–503CrossRefPubMed
54.
Zurück zum Zitat Nieto FJ, Peppard PE, Young T, Finn L, Hla KM, Farré R (2012) Sleep-disordered breathing and cancer mortality: results from the Wisconsin Sleep Cohort Study. Am J Respir Crit Care Med 186:190–194CrossRefPubMedPubMedCentral Nieto FJ, Peppard PE, Young T, Finn L, Hla KM, Farré R (2012) Sleep-disordered breathing and cancer mortality: results from the Wisconsin Sleep Cohort Study. Am J Respir Crit Care Med 186:190–194CrossRefPubMedPubMedCentral
55.
Zurück zum Zitat Campos-Rodriguez F, Martinez-Garcia MA, Martinez M, Duran-Cantolla J, Peña Mde L, Masdeu MJ, Gonzalez M, del Campo F, Gallego I, Marin JM, Barbe F, Montserrat JM, Farre R, Spanish Sleep Network (2013) Association between obstructive sleep apnea and cancer incidence in a large multicenter Spanish cohort. Am J Respir Crit Care Med 187(1):99–105CrossRefPubMed Campos-Rodriguez F, Martinez-Garcia MA, Martinez M, Duran-Cantolla J, Peña Mde L, Masdeu MJ, Gonzalez M, del Campo F, Gallego I, Marin JM, Barbe F, Montserrat JM, Farre R, Spanish Sleep Network (2013) Association between obstructive sleep apnea and cancer incidence in a large multicenter Spanish cohort. Am J Respir Crit Care Med 187(1):99–105CrossRefPubMed
56.
Zurück zum Zitat Almendros I, Wang Y, Becker L, Lennon FE, Zheng J, Coats BR, Schoenfelt KS, Carreras A, Hakim F, Zhang SX, Farré R, Gozal D (2014) Intermittent hypoxia-induced changes in tumor-associated macrophages and tumor malignancy in a mouse model of sleep apnea. Am J Respir Crit Care Med 189(5):593–601CrossRefPubMedPubMedCentral Almendros I, Wang Y, Becker L, Lennon FE, Zheng J, Coats BR, Schoenfelt KS, Carreras A, Hakim F, Zhang SX, Farré R, Gozal D (2014) Intermittent hypoxia-induced changes in tumor-associated macrophages and tumor malignancy in a mouse model of sleep apnea. Am J Respir Crit Care Med 189(5):593–601CrossRefPubMedPubMedCentral
Metadaten
Titel
Schlafstörungen bei Lungenkrankheiten
verfasst von
Prof. Dr. Richard Schulz, MHBA
Dr. Jörg Heitmann
Prof. Dr. Dr. Tim Oliver Hirche
Publikationsdatum
22.05.2017

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