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Current Cardiology Reports
Erschienen in: Current Cardiology Reports 12/2021

01.12.2021 | Hypertension (DS Geller and DL Cohen, Section Editors)

Is Isolated Diastolic Hypertension an Important Phenotype?

verfasst von: Cesar A. Romero, Aldo H. Tabares, Marcelo Orias

Erschienen in: Current Cardiology Reports | Ausgabe 12/2021

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Abstract

Purpose of Review

Isolated diastolic hypertension (IDH) is a frequent hypertension phenotype. We review IDH pathophysiology, risk stratification, and therapeutic decisions.

Recent Findings

Recent guidelines lowering blood pressure cutoff levels have increased IDH prevalence and likely decreased associated cardiovascular risk. Long-term cardiovascular risk and pharmacological intervention in IDH are controversial. Narrow pulse pressure and other physiological and epidemiological characteristics are shared with a systodiastolic hypertension (SDH) subgroup. We propose that IDH be incorporated into a broader category, predominantly diastolic hypertension (PDH), defined by pulse pressure ≤ 45 mmHg and includes IDH and SDH with a narrow pulse pressure.

Summary

IDH-PDH is associated with cardiovascular risk in the long term, especially in young patients. Standardization of the IDH definition and population may contribute to future research to understand genetics, pathophysiology, and eventually therapy in this important subgroup of hypertensive patients.
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Metadaten
Titel
Is Isolated Diastolic Hypertension an Important Phenotype?
verfasst von
Cesar A. Romero
Aldo H. Tabares
Marcelo Orias
Publikationsdatum
01.12.2021
Verlag
Springer US
Erschienen in
Current Cardiology Reports / Ausgabe 12/2021
Print ISSN: 1523-3782
Elektronische ISSN: 1534-3170
DOI
https://doi.org/10.1007/s11886-021-01609-w

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