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Lasers in Medical Science OnlineFirst articles

17.05.2022 | Original Article

Morphological parameters predicting subthreshold micropulse laser effectiveness in central serous chorioretinopathy

CSC is a chorioretinal disease in the pachychoroid disease spectrum and is characterized by pachychoroid, RPE irregularities, and subretinal fluid accumulation. At presentation, patients mostly describe a dark circle or shadow in the central …

verfasst von:
Peter Kiraly, Jaka Smrekar, Polona Jaki Mekjavić

10.05.2022 | Original Article

Endolift laser an effective method for the lower eye bag treatment: a case series study

Numerous individuals suffer from the lower eye bag. Lower eye bag treatment is a challenge that might require new methods. Depending on the cause, there are different treatment approaches to reduce puffiness under the eyes. In this pilot study, 9 …

verfasst von:
Mohammad Ali Nilforoushzadeh, Maryam Heidari-Kharaji, Tannaz Fakhim, Niloufar Najar Nobari, Elham Torkamaniha, Amirreza Hanifnia, Elham Behrangi

07.05.2022 | Correction

Correction to: Observation on the efficacy of 1565‑nm non‑ablative fractional laser combined with compound betamethasone topical application on the treatment of early scar in Chinese patients

verfasst von:
Qin Guo, Ping Xu, Jianzhou Ye

04.05.2022 | Brief Report

Excimer light therapy with systemic corticosteroids improved severe chronic nodular prurigo and altered peripheral nerve fibers in the epidermis

Chronic nodular prurigo (CNPG) is a pruritic, chronic skin disease clinically defined by hyperkeratotic or erosive nodules [ 1 – 3 ]. In this study, we focus on patients with severe CNPG on the extremities and trunk who present with itchy skin …

verfasst von:
Tsuyoshi Mitsuishi, Mitsutoshi Tominaga, Kazunori Miyata, Sumika Toyama, Utako Kimura, Yasushi Suga, Kenji Takamori

04.05.2022 | Review Article

Photodynamic therapy for root canal disinfection in endodontics: an umbrella review

To evaluate and synthesize the evidence from the individual reviews that evaluated the efficacy of PDT therapy in root canal disinfection by undertaking an umbrella review. The protocol of the review was registered in the PROSPERO database under …

verfasst von:
Ana Flávia Almeida Barbosa, Carolina Oliveira de Lima, Thiago Moreira, Luciana Moura Sassone, Tatiana Kelly da Silva Fidalgo, Emmanuel João Nogueira Leal Silva

03.05.2022 | Original Article

Raman spectroscopy and sciatic functional index (SFI) after low-level laser therapy (LLLT) in a rat sciatic nerve crush injury model

Axonotmesis causes sensorimotor and neurofunctional deficits, and its regeneration can occur slowly or not occur if not treated appropriately. Low-level laser therapy (LLLT) promotes nerve regeneration with the proliferation of myelinating Schwann …

verfasst von:
Melissa de Almeida Melo Maciel Mangueira, Egas Caparelli-Dáquer, Ozimo Pereira Gama Filho, Diogo Souza Ferreira Rubim de Assis, Janyeid Karla Castro Sousa, Willy Leite Lima, Antonio Luiz Barbosa Pinheiro, Landulfo Silveira Jr, Nilton Maciel Mangueira

02.05.2022 | Original Article

180-W GreenLight laser photoselective vaporization with multiple triamcinolone acetonide injections for the treatment of bladder neck contractures

Bladder neck contracture (BNC), one of the most challenging complications after transurethral resection of the prostate (TURP) and photoselective vaporization of the prostate (PVP), lacks effective treatment. In the present study, our experience …

verfasst von:
Xiaoliang Sun, Xunbo Jin, Kang Leng, Yong Zhao, Haiyang Zhang

02.05.2022 | Original Article

Effect of photobiomodulation on fatigue in individuals with relapsing–remitting multiple sclerosis: a pilot study

Multiple sclerosis is an autoimmune disease of the central nervous system characterized by inflammation and destruction of the myelin sheath. Fatigue is one of the main symptoms of this disease, with a negative impact on quality of life and few …

verfasst von:
Tamiris Silva, Raquel Candido Alencar, Bruna Cristina de Souza Silva, Elaine Cristina Oliveira Martins Viana, Yara Dadalti Fragoso, Andréa Oliver Gomes, Maria Cristina Chavantes, Alessandro Melo Deana, Juliana Maria Altavista Sagretti Gallo, Kristianne Porta Santos Fernandes, Raquel Agnelli Mesquita-Ferrari, Sandra Kalil Bussadori

01.05.2022 | Original Article

Efficacy and safety of 755-nm picosecond alexandrite laser with topical tranexamic acid versus laser monotherapy for melasma and facial rejuvenation: a multicenter, randomized, double-blinded, split-face study in Chinese patients

To compare the efficacy and safety of 755-nm picosecond alexandrite laser and topical tranexamic acid (TTA) combination therapy with laser monotherapy, for the treatment of melasma and facial rejuvenation. This multicenter, randomized …

verfasst von:
Yiming Li, Cheng Yao, Heye Zhang, Li Li, Yiyi Song

29.04.2022 | Review Article

Efficacy of laser therapy combined with topical antifungal agents for onychomycosis: a systematic review and meta-analysis of randomised controlled trials

Onychomycosis, a fungal infection of the nail, is one of the most common nail diseases worldwide [ 1 ]. The prevalence of onychomycosis varies geographically. Onychomycosis rates range from 8.7 to 13.8% in North America, whereas the range is …

verfasst von:
Jianfeng Zhang, Peng Lin, Junchen Li, Chenqi Guo, Jingbo Zhai, Yu Zhang

28.04.2022 | Original Article

Observation on the efficacy of 1565-nm non-ablative fractional laser combined with compound betamethasone topical application on the treatment of early scar in Chinese patients

The objective of the study was to evaluate the efficacy of combining 1565-nm non-ablative fractional laser with low-dose compound betamethasone topical application in the treatment of immature early red hypertrophic scar. We enrolled 38 cases of …

verfasst von:
Qin Guo, Ping Xu, Jianzhou Ye

27.04.2022 | Original Article

Safety and efficacy of a low-level radiofrequency thermal treatment in an animal model of obstructive meibomian gland dysfunction

This study aimed to evaluate the safety and efficacy of a low-level radiofrequency thermal treatment in an obstructive MGD rabbit model. Meibomian gland orifices of the central two-thirds of the upper and lower eyelid margins were coagulated twice …

verfasst von:
Jung Yeob Han, So Young Park, Jeong Hye Sunwoo, Jae Yong Kim, Hungwon Tchah, Hun Lee

25.04.2022 | Original Article

Meta-analysis of prognostic factors related to early urinary incontinence following new transurethral procedures dominated by laser therapy for benign prostatic hyperplasia

To investigate the predictors of early postoperative UI after new minimally transurethral procedures dominated by laser therapy for benign prostatic hyperplasia. A literature review of articles published before June 30, 2021 was conducted using …

verfasst von:
Guiya Jiang, Tieshi Liu

19.04.2022 | Original Article

Effects of moderate aerobic exercise, low-level laser therapy, or their combination on muscles pathology, oxidative stress and irisin levels in the mdx mouse model of Duchenne muscular dystrophy

This study aimed to investigate how the combined use of low-level laser therapy (LLLT) and exercise, to reduce the possible side effects and/or increase the benefits of exercise, would affect oxidative stress, utrophin, irisin peptide, and …

verfasst von:
Sılasu Arıkan, Nuray Alaca, Dilek Özbeyli, Merve Açıkel Elmas, Serap Arbak, Guldal Suyen

Open Access 18.04.2022 | Original Article

A nutraceutical formulation combined with sclerofoam-assisted laser treatment ameliorates chronic venous insufficiency

Chronic venous insufficiency has a high impact on the healthcare system due to its high incidence worldwide. We performed a study in 30 women with thigh and leg varices due to major saphenous vein valve incontinence with saphenous trunk reflux …

verfasst von:
Beniamino Palmieri, Maria Vadalà, Simone Ugo Urso, Laura Ornella Baldini, Caterina Fanelli, Julio Cesar Morales-Medina, Tommaso Iannitti

14.04.2022 | Original Article

Photobiomodulation stimulates surrounding bone formation and increases stability of titanium alloy miniscrews in ovariectomized rats

The number of older individuals (> 60 years) treated in orthodontic dental practice is constantly growing, and osteoporosis is a common disease within this age range. Orthodontic treatment for this group tends to be challenging, often requiring …

verfasst von:
Bruna Guimarães Martins, Vanessa Santos de Moura, Denise Nami Fujii, Aguinaldo Silva Garcez, Selly Sayuri Suzuki

12.04.2022 | Original Article

Efficacy and safety of a thermal fractional skin rejuvenation system (Tixel) for the treatment of facial and/or scalp actinic keratoses

Actinic keratoses are common cutaneous lesions with a potential to progress to invasive squamous cell carcinoma. Therefore, treatment is crucial. The Tixel® is a noninvasive thermomechanical device designed to transfer heat to the upper dermis in …

verfasst von:
Meital Oren-Shabtai, Nadezhda Sloutsky, Moshe Lapidoth, Daniel Mimouni, Ilia Chorny, Igor Snast, Yael Anne Leshem, Rivka Friedland, Emmilia Hodak, Ifat Klein, Yael Agmon, Assi Levi

11.04.2022 | Review Article

Light-emitting diode phototherapy: pain relief and underlying mechanisms

Pain is a common symptom of an illness. For decades, pain treatments such as non-steroidal anti-inflammatory drugs, opioids, and surgical nerve blocking have been widely used, but each method has its limitations. Photobiomodulation is a recently …

verfasst von:
Wen-Wen Zhang, Xin-Yue Wang, Yu-Xia Chu, Yan-Qing Wang

08.04.2022 | Original Article

Photobiomodulation Therapy Affects the Elastic Modulus, Cytoskeletal Rearrangement and Migration Capability of Human Osteosarcoma Cells

Photobiomodulation (PBM) therapy utilizes low-power lasers to modulate the viability of living human cells and leads to changes in proliferation, differentiation, adhesion and gene expression, even though the rearrangement of cytoskeleton was not …

verfasst von:
Amin Barati Shoorche, Alireza Mohammadkarim, Majid Jadidi, Marjan Bahraminasab

Open Access 08.04.2022 | Original Article

Multiphoton microscopy providing pathological-level quantification of myocardial fibrosis in transplanted human heart

Multiphoton microscopy (MPM), a high-resolution laser scanning technique, has been shown to provide detailed real-time information on fibrosis assessment in animal models. But the value of MPM in human histology, especially in heart tissue, has …

verfasst von:
Yuelong Yang, Liqin Zheng, Zhen Li, Jianhua Chen, Xinyi Wu, Guanmin Ren, Zebin Xiao, Xiaodan Li, Wei Luo, Zhigang Wu, Liming Nie, Jianxin Chen, Hui Liu