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Journal of the Association for Research in Otolaryngology OnlineFirst articles

15.04.2024 | Original Article

FDA-Approved Tedizolid Phosphate Prevents Cisplatin-Induced Hearing Loss Without Decreasing Its Anti-tumor Effect

Since its approval for clinical use by the Food and Drug Administration (FDA) in 1978, cisplatin has provided an effective treatment for life-threatening solid tumors, including lung cancer and nerve tumors [ 1 , 2 ]. However, cisplatin is …

verfasst von:
Zhiwei Yao, Yu Xiao, Wen Li, Shuhui Kong, Hailong Tu, Siwei Guo, Ziyi Liu, Lushun Ma, Ruifeng Qiao, Song Wang, Miao Chang, Xiaoxu Zhao, Yuan Zhang, Lei Xu, Daqing Sun, Xiaolong Fu

15.04.2024 | Original Article

Hampshire Sheep as a Large-Animal Model for Cochlear Implantation

Large-animal models can be used to study cochlear implantation with the same commercial electrode arrays that are used in humans. Cochlear implantation has been studied in several animal models, including non-human primates, cats, mini pigs …

verfasst von:
Nicholas A. Waring, Alexander Chern, Brandon J. Vilarello, Yew Song Cheng, Chaoqun Zhou, Jeffrey H. Lang, Elizabeth S. Olson, Hideko Heidi Nakajima

02.04.2024 | Review

Echolocating Bats Have Evolved Decreased Susceptibility to Noise-Induced Temporary Hearing Losses

Glenis Long championed the application of quantitative psychophysical methods to understand comparative hearing abilities across species. She contributed the first psychophysical studies of absolute and masked hearing sensitivities in an auditory …

verfasst von:
Andrea Megela Simmons, James A. Simmons

01.04.2024 | Original Article

Mechanical Effects of Medical Device Attachment to Human Tympanic Membrane

Implantable middle ear hearing devices can be used as an effective solution to help people with different kinds of hearing impairments. An example of an existing application is the tympanostomy tube insertion. These tubes are inserted into the …

verfasst von:
Arash Ebrahimian, Hossein Mohammadi, Nima Maftoon

Open Access 26.03.2024 | Perspectives

Tinnitus: Clinical Insights in Its Pathophysiology-A Perspective

Tinnitus, the perception of sound without a corresponding external sound source, and tinnitus disorder, which is tinnitus with associated suffering, present a multifaceted clinical challenge due to its heterogeneity and its incompletely understood …

verfasst von:
Berthold Langguth, Dirk de Ridder, Winfried Schlee, Tobias Kleinjung