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2016 | OriginalPaper | Buchkapitel

24. Krankheiten der Basalganglien

verfasst von : Prof. Dr. Daniela Berg

Erschienen in: Neurologie

Verlag: Springer Berlin Heidelberg

Zusammenfassung

Diagnose und Therapie des M. Parkinson und anderer Bewegungsstörungen haben große Fortschritte gemacht: Parallel zur Aufklärung der Funktion der Basalganglien in der Regulation der Motorik sind Genetik, Pathophysiologie und Therapie des M. Parkinson und auch anderer Bewegungsstörungen intensiv erforscht worden. Den Patienten können heute differenzierte Behandlungsprogramme angeboten werden, die die Prognose gegenüber der jüngeren Vergangenheit erheblich verbessern. Dies schließt die elektrische Stimulation (»Schrittmacher«) von extrapyramidalen Kernen (z. B. Ncl. subthalamicus) ein.
Literatur
Zurück zum Zitat Berardelli A, Wenning GK, Antonini A, Berg D, Bloem BR, Bonifati V, Brooks D, Burn DJ, Colosimo C, Fanciulli A, Ferreira J, Gasser T, Grandas F, Kanovsky P, Kostic V, Kulisevsky J, Oertel W, Poewe W, Reese JP, Relja M, Ruzicka E, Schrag A, Seppi K, Taba P, Vidailhet M (2013) EFNS/MDS-ES/ENS recommendations for the diagnosis of Parkinson’s disease. Eur J Neurol 20(1):16–34 Berardelli A, Wenning GK, Antonini A, Berg D, Bloem BR, Bonifati V, Brooks D, Burn DJ, Colosimo C, Fanciulli A, Ferreira J, Gasser T, Grandas F, Kanovsky P, Kostic V, Kulisevsky J, Oertel W, Poewe W, Reese JP, Relja M, Ruzicka E, Schrag A, Seppi K, Taba P, Vidailhet M (2013) EFNS/MDS-ES/ENS recommendations for the diagnosis of Parkinson’s disease. Eur J Neurol 20(1):16–34
Zurück zum Zitat Berg D, Godau J, Walter U (2008) Transcranial sonography in movement disorders. Lancet Neurol 7(11):1044–55CrossRef Berg D, Godau J, Walter U (2008) Transcranial sonography in movement disorders. Lancet Neurol 7(11):1044–55CrossRef
Zurück zum Zitat Berg D, Postuma RB, Bloem B, Chan P, Dubois B, Gasser T, Goetz CG, Halliday GM, Hardy J, Lang AE, Litvan I, Marek K, Obeso J, Oertel W, Olanow CW, Poewe W, Stern M, Deuschl G (2014) Time to redefine PD? Introductory statement of the MDS Task Force on the definition of Parkinson’s disease. Mov Disord 29(4):454–62CrossRef Berg D, Postuma RB, Bloem B, Chan P, Dubois B, Gasser T, Goetz CG, Halliday GM, Hardy J, Lang AE, Litvan I, Marek K, Obeso J, Oertel W, Olanow CW, Poewe W, Stern M, Deuschl G (2014) Time to redefine PD? Introductory statement of the MDS Task Force on the definition of Parkinson’s disease. Mov Disord 29(4):454–62CrossRef
Zurück zum Zitat Braak H et al. (2003) Staging of brain pathology related to sporadic Parkinson’s disease. Neurobiol Aging 24: 197–211CrossRef Braak H et al. (2003) Staging of brain pathology related to sporadic Parkinson’s disease. Neurobiol Aging 24: 197–211CrossRef
Zurück zum Zitat Dunning CJ, George S, Brundin P (2013) What’s to like about the prion-like hypothesis for the spreading of aggregated α-synuclein in Parkinson disease? Prion 7(1):92–7CrossRef Dunning CJ, George S, Brundin P (2013) What’s to like about the prion-like hypothesis for the spreading of aggregated α-synuclein in Parkinson disease? Prion 7(1):92–7CrossRef
Zurück zum Zitat Garcia-Borreguero D1, Ferini-Strambi L, Kohnen R, O’Keeffe S, Trenkwalder C, Högl B, Benes H, Jennum P, Partinen M, Fer D, Montagna P, Bassetti CL, Iranzo A, Sonka K, Williams AM; European Federation of Neurological Societies; European Neurological Society; European Sleep Research Society (2012) European guidelines on management of restless legs syndrome: report of a joint task force by the European Federation of Neurological Societies, the European Neurological Society and the European Sleep Research Society. Eur J Neurol 19(11):1385–96CrossRef Garcia-Borreguero D1, Ferini-Strambi L, Kohnen R, O’Keeffe S, Trenkwalder C, Högl B, Benes H, Jennum P, Partinen M, Fer D, Montagna P, Bassetti CL, Iranzo A, Sonka K, Williams AM; European Federation of Neurological Societies; European Neurological Society; European Sleep Research Society (2012) European guidelines on management of restless legs syndrome: report of a joint task force by the European Federation of Neurological Societies, the European Neurological Society and the European Sleep Research Society. Eur J Neurol 19(11):1385–96CrossRef
Zurück zum Zitat Goedert M, Spillantini MG, Del Tredici K, Braak H (2013) 100 years of Lewy pathology. Nat Rev Neurol 9(1):13–24CrossRef Goedert M, Spillantini MG, Del Tredici K, Braak H (2013) 100 years of Lewy pathology. Nat Rev Neurol 9(1):13–24CrossRef
Zurück zum Zitat Mills K, Mari Z (2015) An update and review of the treatment of myoclonus. Curr Neurol Neurosci Rep 15(1):512 Mills K, Mari Z (2015) An update and review of the treatment of myoclonus. Curr Neurol Neurosci Rep 15(1):512
Zurück zum Zitat Paudel R, Hardy J, Revesz T, Holton JL, Houlden H (2012) Review: genetics and neuropathology of primary pure dystonia. Neuropathol Appl Neurobiol 38(6):520–34CrossRef Paudel R, Hardy J, Revesz T, Holton JL, Houlden H (2012) Review: genetics and neuropathology of primary pure dystonia. Neuropathol Appl Neurobiol 38(6):520–34CrossRef
Zurück zum Zitat Perestelo-Pérez L, Rivero-Santana A, Pérez-Ramos J, Serrano-Pérez P, Panetta J, Hilarion P (2014) Deep brain stimulation in Parkinson’s disease: meta-analysis of randomized controlled trials. J Neurol 261(11):2051–60CrossRef Perestelo-Pérez L, Rivero-Santana A, Pérez-Ramos J, Serrano-Pérez P, Panetta J, Hilarion P (2014) Deep brain stimulation in Parkinson’s disease: meta-analysis of randomized controlled trials. J Neurol 261(11):2051–60CrossRef
Zurück zum Zitat Puschmann A, Wszolek ZK (2011) Diagnosis and treatment of common forms of tremor. Semin Neurol 31(1):65–77CrossRef Puschmann A, Wszolek ZK (2011) Diagnosis and treatment of common forms of tremor. Semin Neurol 31(1):65–77CrossRef
Zurück zum Zitat Ross CA, Tabrizi SJ (2011) Huntington’s disease: from molecular pathogenesis to clinical treatment. Lancet Neurol 10(1):83–98CrossRef Ross CA, Tabrizi SJ (2011) Huntington’s disease: from molecular pathogenesis to clinical treatment. Lancet Neurol 10(1):83–98CrossRef
Zurück zum Zitat Schaeffer E, Pilotto A, Berg D (2014) Pharmacological strategies for the management of levodopa-induced dyskinesia in patients with Parkinson’s disease. CNS Drugs 28(12):1155–84CrossRef Schaeffer E, Pilotto A, Berg D (2014) Pharmacological strategies for the management of levodopa-induced dyskinesia in patients with Parkinson’s disease. CNS Drugs 28(12):1155–84CrossRef
Zurück zum Zitat Schneider SA, Deuschl G (2015) Medical and Surgical Treatment of Tremors. Neurol Clin33(1):57–75CrossRef Schneider SA, Deuschl G (2015) Medical and Surgical Treatment of Tremors. Neurol Clin33(1):57–75CrossRef
Zurück zum Zitat Seppi K, Weintraub D, Coelho M, Perez-Lloret S, Fox SH, Katzenschlager R, Hametner EM, Poewe W, Rascol O, Goetz CG, Sampaio C (2011) The Movement Disorder Society Evidence-Based Medicine Review Update: Treatments for the non-motor symptoms of Parkinson’s disease. Mov Disord 26 Suppl 3:S42–80CrossRef Seppi K, Weintraub D, Coelho M, Perez-Lloret S, Fox SH, Katzenschlager R, Hametner EM, Poewe W, Rascol O, Goetz CG, Sampaio C (2011) The Movement Disorder Society Evidence-Based Medicine Review Update: Treatments for the non-motor symptoms of Parkinson’s disease. Mov Disord 26 Suppl 3:S42–80CrossRef
Zurück zum Zitat Singleton AB, Farrer MJ, Bonifati V (2013) The genetics of Parkinson’s disease: progress and therapeutic implications. Mov Disord 28(1):14–23CrossRef Singleton AB, Farrer MJ, Bonifati V (2013) The genetics of Parkinson’s disease: progress and therapeutic implications. Mov Disord 28(1):14–23CrossRef
Zurück zum Zitat Sprenger F, Poewe W (2013) Management of motor and non-motor symptoms in Parkinson’s disease. CNS Drugs 27(4):259–72CrossRef Sprenger F, Poewe W (2013) Management of motor and non-motor symptoms in Parkinson’s disease. CNS Drugs 27(4):259–72CrossRef
Zurück zum Zitat Stamelou M, Bhatia KP (2015) Atypical Parkinsonism: Diagnosis and Treatment. Neurol Clin 33(1):39–56CrossRef Stamelou M, Bhatia KP (2015) Atypical Parkinsonism: Diagnosis and Treatment. Neurol Clin 33(1):39–56CrossRef
Zurück zum Zitat Wenning GK, Krismer F (2013) Multiple system atrophy. Handb Clin Neurol 117:229–41 Wenning GK, Krismer F (2013) Multiple system atrophy. Handb Clin Neurol 117:229–41
Zurück zum Zitat Willams DR et al. (2007) Pathological tau burden and distribution distinguishes progressive supranuclear palsy-parkinsonism from Richardson’s syndrome. Brain 130(Pt 6):1566–76 Willams DR et al. (2007) Pathological tau burden and distribution distinguishes progressive supranuclear palsy-parkinsonism from Richardson’s syndrome. Brain 130(Pt 6):1566–76
Zurück zum Zitat Winkelmann et al. (2007) Genome-wide association study of restless legs syndrome identifies common variants in three genomic regions. Nat Gent 39: 1000–1006 Winkelmann et al. (2007) Genome-wide association study of restless legs syndrome identifies common variants in three genomic regions. Nat Gent 39: 1000–1006
Metadaten
Titel
Krankheiten der Basalganglien
verfasst von
Prof. Dr. Daniela Berg
Copyright-Jahr
2016
Verlag
Springer Berlin Heidelberg
DOI
https://doi.org/10.1007/978-3-662-46892-0_24