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Erschienen in: Die Urologie 10/2022

29.08.2022 | Magnetresonanztomografie | CME

Bildgesteuerte Biopsie der Prostata

verfasst von: Dr. med. August Sigle, Jakob Michaelis, Dominik Schöb, Matthias Benndorf, Lars Schimmöller, Benedikt Becker, Maximilian Pallauf, Andreas J. Gross, Thomas R. W. Herrmann, Jan-Thorsten Klein, Lukas Lusuardi, Christopher Netsch, Axel Häcker, Jens Westphal, Cordula Jilg, Christian Gratzke, Arkadiusz Miernik

Erschienen in: Die Urologie | Ausgabe 10/2022

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Zusammenfassung

Die Empfehlung zur Durchführung einer multiparametrischen Magnetresonanztomographie (mpMRT) in der Primärdiagnostik und während aktiver Überwachung des Prostatakarzinoms beinhaltet als Konsequenz eine bildgesteuerte Probenentnahme aus den auffälligen Arealen. Hierbei wird die Lokalisationsinformation aus den MRT-Bildern für eine gezielte Biopsie tumorsuspekter Areale genutzt. Die gezielte Probenentnahme wird in der Regel unter sonographischer Kontrolle und nach MRT-Ultraschall-Fusion durchgeführt, kann aber auch (meist in speziellen Fällen) direkt im MR-Tomographen erfolgen. Bei einer ultraschallkontrollierten Probenentnahme muss eine Koregistrierung mit den MRT-Bildern (Segmentierung der Prostatakontur und Registrierung suspekter Befunde) erfolgen. Diese Koregistrierung kann entweder kognitiv (alleinige Transferleistung durch die biopsierende Person) oder softwarebasiert durchgeführt werden. Jedes der Verfahren zeigt spezifische Vor- und Nachteile im Spannungsfeld zwischen diagnostischer Genauigkeit und Ressourcenaufwand.
Literatur
1.
Zurück zum Zitat Hodge KK, McNeal JE, Terris MK, Stamey TA (1989) Random systematic versus directed ultrasound guided transrectal core biopsies of the prostate. J Urol 142(1):71–74 (discussion 4–5)CrossRef Hodge KK, McNeal JE, Terris MK, Stamey TA (1989) Random systematic versus directed ultrasound guided transrectal core biopsies of the prostate. J Urol 142(1):71–74 (discussion 4–5)CrossRef
2.
Zurück zum Zitat Schoots IG, Padhani AR (2020) Delivering Clinical impacts of the MRI diagnostic pathway in prostate cancer diagnosis. Abdom Radiol 45(12):4012–4022CrossRef Schoots IG, Padhani AR (2020) Delivering Clinical impacts of the MRI diagnostic pathway in prostate cancer diagnosis. Abdom Radiol 45(12):4012–4022CrossRef
3.
Zurück zum Zitat van der Leest M, Cornel E, Israel B, Hendriks R, Padhani AR, Hoogenboom M et al (2019) Head-to-head comparison of transrectal ultrasound-guided prostate biopsy versus multiparametric prostate resonance imaging with subsequent magnetic resonance-guided biopsy in biopsy-naive men with elevated prostate-specific antigen: a large prospective multicenter clinical study. Eur Urol 75(4):570–578CrossRef van der Leest M, Cornel E, Israel B, Hendriks R, Padhani AR, Hoogenboom M et al (2019) Head-to-head comparison of transrectal ultrasound-guided prostate biopsy versus multiparametric prostate resonance imaging with subsequent magnetic resonance-guided biopsy in biopsy-naive men with elevated prostate-specific antigen: a large prospective multicenter clinical study. Eur Urol 75(4):570–578CrossRef
4.
Zurück zum Zitat Halpern EJ, Strup SE (2000) Using gray-scale and color and power Doppler sonography to detect prostatic cancer. AJR Am J Roentgenol 174(3):623–627CrossRef Halpern EJ, Strup SE (2000) Using gray-scale and color and power Doppler sonography to detect prostatic cancer. AJR Am J Roentgenol 174(3):623–627CrossRef
6.
Zurück zum Zitat Li Y, Tang J, Fei X, Gao Y (2013) Diagnostic performance of contrast enhanced ultrasound in patients with prostate cancer: a meta-analysis. Acad Radiol 20(2):156–164CrossRef Li Y, Tang J, Fei X, Gao Y (2013) Diagnostic performance of contrast enhanced ultrasound in patients with prostate cancer: a meta-analysis. Acad Radiol 20(2):156–164CrossRef
8.
Zurück zum Zitat Wildeboer RR, Mannaerts CK, van Sloun RJG, Budaus L, Tilki D, Wijkstra H et al (2020) Automated multiparametric localization of prostate cancer based on B‑mode, shear-wave elastography, and contrast-enhanced ultrasound radiomics. Eur Radiol 30(2):806–815CrossRef Wildeboer RR, Mannaerts CK, van Sloun RJG, Budaus L, Tilki D, Wijkstra H et al (2020) Automated multiparametric localization of prostate cancer based on B‑mode, shear-wave elastography, and contrast-enhanced ultrasound radiomics. Eur Radiol 30(2):806–815CrossRef
9.
Zurück zum Zitat Ghai S, Eure G, Fradet V, Hyndman ME, McGrath T, Wodlinger B et al (2016) Assessing cancer risk on novel 29 MHz micro-ultrasound images of the prostate: creation of the micro-ultrasound protocol for prostate risk identification. J Urol 196(2):562–569CrossRef Ghai S, Eure G, Fradet V, Hyndman ME, McGrath T, Wodlinger B et al (2016) Assessing cancer risk on novel 29 MHz micro-ultrasound images of the prostate: creation of the micro-ultrasound protocol for prostate risk identification. J Urol 196(2):562–569CrossRef
10.
Zurück zum Zitat Klotz L, Lughezzani G, Maffei D, Sanchez A, Pereira JG, Staerman F et al (2021) Comparison of micro-ultrasound and multiparametric magnetic resonance imaging for prostate cancer: a multicenter, prospective analysis. Can Urol Assoc J 15(1):E11–E16PubMed Klotz L, Lughezzani G, Maffei D, Sanchez A, Pereira JG, Staerman F et al (2021) Comparison of micro-ultrasound and multiparametric magnetic resonance imaging for prostate cancer: a multicenter, prospective analysis. Can Urol Assoc J 15(1):E11–E16PubMed
12.
Zurück zum Zitat Franiel T, Asbach P, Beyersdorff D, Blondin D, Kaufmann S, Mueller-Lisse UG et al (2021) mpMRI of the Prostate (MR-Prostatography): Updated Recommendations of the DRG and BDR on Patient Preparation and Scanning Protocol. Rofo 193(7):763–777PubMed Franiel T, Asbach P, Beyersdorff D, Blondin D, Kaufmann S, Mueller-Lisse UG et al (2021) mpMRI of the Prostate (MR-Prostatography): Updated Recommendations of the DRG and BDR on Patient Preparation and Scanning Protocol. Rofo 193(7):763–777PubMed
15.
Zurück zum Zitat Eklund M, Jaderling F, Discacciati A, Bergman M, Annerstedt M, Aly M et al (2021) MRI-targeted or standard biopsy in prostate cancer screening. N Engl J Med 385(10):908–920CrossRef Eklund M, Jaderling F, Discacciati A, Bergman M, Annerstedt M, Aly M et al (2021) MRI-targeted or standard biopsy in prostate cancer screening. N Engl J Med 385(10):908–920CrossRef
16.
Zurück zum Zitat Klotz L, Chin J, Black PC, Finelli A, Anidjar M, Bladou F et al (2021) Comparison of multiparametric magnetic resonance imaging-targeted biopsy with systematic transrectal ultrasonography biopsy for biopsy-naive men at risk for prostate cancer: a phase 3 randomized clinical trial. JAMA Oncol 7(4):534–542CrossRef Klotz L, Chin J, Black PC, Finelli A, Anidjar M, Bladou F et al (2021) Comparison of multiparametric magnetic resonance imaging-targeted biopsy with systematic transrectal ultrasonography biopsy for biopsy-naive men at risk for prostate cancer: a phase 3 randomized clinical trial. JAMA Oncol 7(4):534–542CrossRef
17.
Zurück zum Zitat Bittencourt LK, Guricova K, Zucker I, Durieux JC, Schoots IG (2022) Risk-based MRI-directed diagnostic pathway outperforms non-risk-based pathways in suspected prostate cancer biopsy-naive men: a large cohort validation study. Eur Radiol 32(4):2330–2339CrossRef Bittencourt LK, Guricova K, Zucker I, Durieux JC, Schoots IG (2022) Risk-based MRI-directed diagnostic pathway outperforms non-risk-based pathways in suspected prostate cancer biopsy-naive men: a large cohort validation study. Eur Radiol 32(4):2330–2339CrossRef
18.
Zurück zum Zitat Kwak JT, Hong CW, Pinto PA, Williams M, Xu S, Kruecker J et al (2015) Is visual registration equivalent to semiautomated registration in prostate biopsy? Biomed Res Int 2015:394742CrossRef Kwak JT, Hong CW, Pinto PA, Williams M, Xu S, Kruecker J et al (2015) Is visual registration equivalent to semiautomated registration in prostate biopsy? Biomed Res Int 2015:394742CrossRef
19.
Zurück zum Zitat Halstuch D, Baniel J, Lifshitz D, Sela S, Ber Y, Margel D (2019) Characterizing the learning curve of MRI-US fusion prostate biopsies. Prostate Cancer Prostatic Dis 22(4):546–551CrossRef Halstuch D, Baniel J, Lifshitz D, Sela S, Ber Y, Margel D (2019) Characterizing the learning curve of MRI-US fusion prostate biopsies. Prostate Cancer Prostatic Dis 22(4):546–551CrossRef
20.
Zurück zum Zitat Wegelin O, Exterkate L, van der Leest M, Kummer JA, Vreuls W, de Bruin PC, et al. The FUTURE Trial (2019) A multicenter randomised controlled trial on target biopsy techniques based on magnetic resonance imaging in the diagnosis of prostate cancer in patients with prior negative biopsies. Eur Urol 75(4):582–590CrossRef Wegelin O, Exterkate L, van der Leest M, Kummer JA, Vreuls W, de Bruin PC, et al. The FUTURE Trial (2019) A multicenter randomised controlled trial on target biopsy techniques based on magnetic resonance imaging in the diagnosis of prostate cancer in patients with prior negative biopsies. Eur Urol 75(4):582–590CrossRef
21.
Zurück zum Zitat Klingebiel M, Ullrich T, Rabenalt R, Albers P, Antoch G, Schimmoller L (2018) Rofo 190(11):1067–1069CrossRef Klingebiel M, Ullrich T, Rabenalt R, Albers P, Antoch G, Schimmoller L (2018) Rofo 190(11):1067–1069CrossRef
22.
Zurück zum Zitat Venderink W, Bomers JG, Overduin CG, Padhani AR, de Lauw GR, Sedelaar MJ et al (2020) Multiparametric magnetic resonance imaging for the detection of clinically significant prostate cancer: what urologists need to know. Part 3: targeted biopsy. Eur Urol 77(4):481–490CrossRef Venderink W, Bomers JG, Overduin CG, Padhani AR, de Lauw GR, Sedelaar MJ et al (2020) Multiparametric magnetic resonance imaging for the detection of clinically significant prostate cancer: what urologists need to know. Part 3: targeted biopsy. Eur Urol 77(4):481–490CrossRef
23.
Zurück zum Zitat Venderink W, de Rooij M, Sedelaar JPM, Huisman HJ, Futterer JJ (2018) Elastic versus rigid image registration in magnetic resonance imaging-transrectal ultrasound fusion prostate biopsy: a systematic review and meta-analysis. Eur Urol Focus 4(2):219–227CrossRef Venderink W, de Rooij M, Sedelaar JPM, Huisman HJ, Futterer JJ (2018) Elastic versus rigid image registration in magnetic resonance imaging-transrectal ultrasound fusion prostate biopsy: a systematic review and meta-analysis. Eur Urol Focus 4(2):219–227CrossRef
24.
Zurück zum Zitat Sokolakis I, Pyrgidis N, Koneval L, Krebs M, Thurner A, Kubler H et al (2021) Usability and diagnostic accuracy of different MRI/ultrasound-guided fusion biopsy systems for the detection of clinically significant and insignificant prostate cancer: a prospective cohort study. World J Urol 39(11):4101–4108CrossRef Sokolakis I, Pyrgidis N, Koneval L, Krebs M, Thurner A, Kubler H et al (2021) Usability and diagnostic accuracy of different MRI/ultrasound-guided fusion biopsy systems for the detection of clinically significant and insignificant prostate cancer: a prospective cohort study. World J Urol 39(11):4101–4108CrossRef
26.
Zurück zum Zitat Grummet J, Gorin MA, Popert R, O’Brien T, Lamb AD, Hadaschik B et al (2020) “TREXIT 2020”: why the time to abandon transrectal prostate biopsy starts now. Prostate Cancer Prostatic Dis 23(1):62–65CrossRef Grummet J, Gorin MA, Popert R, O’Brien T, Lamb AD, Hadaschik B et al (2020) “TREXIT 2020”: why the time to abandon transrectal prostate biopsy starts now. Prostate Cancer Prostatic Dis 23(1):62–65CrossRef
27.
Zurück zum Zitat Tu X, Liu Z, Chang T, Qiu S, Xu H, Bao Y et al (2019) Transperineal magnetic resonance imaging-targeted biopsy May perform better than transrectal route in the detection of clinically significant prostate cancer: systematic review and meta-analysis. Clin Genitourin Cancer 17(5):e860–e870CrossRef Tu X, Liu Z, Chang T, Qiu S, Xu H, Bao Y et al (2019) Transperineal magnetic resonance imaging-targeted biopsy May perform better than transrectal route in the detection of clinically significant prostate cancer: systematic review and meta-analysis. Clin Genitourin Cancer 17(5):e860–e870CrossRef
28.
Zurück zum Zitat N. Mottet PC, R.C.N. van den Bergh, E. Briers MDS, S. Gillessen, J. Grummet AMH, T.H. van der Kwast, T.B. Lam, M.D. Mason SOH, D.E. Oprea-Lager, G. Ploussard, H.G. van der Poel OR, I.G. Schoots. D. Tilki, T. Wiegel, Guidelines Associates: T. Van den Broeck MC, et al. EAU-EANM-ESTRO-ESUR-ISUP_SIOG-Guidelines-on-Prostate-Cancer-2022. 2022. N. Mottet PC, R.C.N. van den Bergh, E. Briers MDS, S. Gillessen, J. Grummet AMH, T.H. van der Kwast, T.B. Lam, M.D. Mason SOH, D.E. Oprea-Lager, G. Ploussard, H.G. van der Poel OR, I.G. Schoots. D. Tilki, T. Wiegel, Guidelines Associates: T. Van den Broeck MC, et al. EAU-EANM-ESTRO-ESUR-ISUP_SIOG-Guidelines-on-Prostate-Cancer-2022. 2022.
32.
Zurück zum Zitat Xiang J, Yan H, Li J, Wang X, Chen H, Zheng X (2019) Transperineal versus transrectal prostate biopsy in the diagnosis of prostate cancer: a systematic review and meta-analysis. World J Surg Oncol 17(1):31CrossRef Xiang J, Yan H, Li J, Wang X, Chen H, Zheng X (2019) Transperineal versus transrectal prostate biopsy in the diagnosis of prostate cancer: a systematic review and meta-analysis. World J Surg Oncol 17(1):31CrossRef
33.
Zurück zum Zitat Park KJ, Choi SH, Lee JS, Kim JK, Kim MH (2020) Interreader agreement with prostate imaging reporting and data system version 2 for prostate cancer detection: a systematic review and meta-analysis. J Urol 204(4):661–670CrossRef Park KJ, Choi SH, Lee JS, Kim JK, Kim MH (2020) Interreader agreement with prostate imaging reporting and data system version 2 for prostate cancer detection: a systematic review and meta-analysis. J Urol 204(4):661–670CrossRef
35.
Zurück zum Zitat Wegelin O, van Melick HHE, Hooft L, Bosch JLHR, Reitsma HB, Barentsz JO et al (2017) Comparing three different techniques for magnetic resonance imaging-targeted prostate biopsies: a systematic review of in-bore versus magnetic resonance imaging-transrectal ultrasound fusion versus cognitive registration. Is there a preferred technique? Eur Urol 71(4):517–531 (https://linkinghub.elsevier.com/retrieve/pii/S0302283816304468)CrossRef Wegelin O, van Melick HHE, Hooft L, Bosch JLHR, Reitsma HB, Barentsz JO et al (2017) Comparing three different techniques for magnetic resonance imaging-targeted prostate biopsies: a systematic review of in-bore versus magnetic resonance imaging-transrectal ultrasound fusion versus cognitive registration. Is there a preferred technique? Eur Urol 71(4):517–531 (https://​linkinghub.​elsevier.​com/​retrieve/​pii/​S030228381630446​8)CrossRef
Metadaten
Titel
Bildgesteuerte Biopsie der Prostata
verfasst von
Dr. med. August Sigle
Jakob Michaelis
Dominik Schöb
Matthias Benndorf
Lars Schimmöller
Benedikt Becker
Maximilian Pallauf
Andreas J. Gross
Thomas R. W. Herrmann
Jan-Thorsten Klein
Lukas Lusuardi
Christopher Netsch
Axel Häcker
Jens Westphal
Cordula Jilg
Christian Gratzke
Arkadiusz Miernik
Publikationsdatum
29.08.2022
Verlag
Springer Medizin
Erschienen in
Die Urologie / Ausgabe 10/2022
Print ISSN: 2731-7064
Elektronische ISSN: 2731-7072
DOI
https://doi.org/10.1007/s00120-022-01929-x

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