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Molecular Autism

Ausgabe 1/2021

Inhalt (74 Artikel)

Open Access Research

Targeting the RHOA pathway improves learning and memory in adult Kctd13 and 16p11.2 deletion mouse models

Sandra Martin Lorenzo, Valérie Nalesso, Claire Chevalier, Marie-Christine Birling, Yann Herault

Open Access Research

Major motor and gait deficits with sexual dimorphism in a Shank3 mutant mouse model

Emmanuel Matas, Alexandre Maisterrena, Mathieu Thabault, Eric Balado, Maureen Francheteau, Anais Balbous, Laurie Galvan, Mohamed Jaber

Open Access Methodology

Application of Airy beam light sheet microscopy to examine early neurodevelopmental structures in 3D hiPSC-derived human cortical spheroids

Dwaipayan Adhya, George Chennell, James A. Crowe, Eva P. Valencia-Alarcón, James Seyforth, Neveen A. Hosny, Marina V. Yasvoina, Robert Forster, Simon Baron-Cohen, Anthony C. Vernon, Deepak P. Srivastava

Open Access Research

Cross-level analysis of molecular and neurobehavioral function in a prospective series of patients with germline heterozygous PTEN mutations with and without autism

Thomas W. Frazier, Ritika Jaini, Robyn M. Busch, Matthew Wolf, Tammy Sadler, Patricia Klaas, Antonio Y. Hardan, Julian A. Martinez-Agosto, Mustafa Sahin, Charis Eng, Simon K. Warfield, Benoit Scherrer, Kira Dies, Rajna Filip-Dhima, Amanda Gulsrud, Ellen Hanson, Jennifer M. Phillips

Open Access Research

Cannabinoid treatment for autism: a proof-of-concept randomized trial

Adi Aran, Moria Harel, Hanoch Cassuto, Lola Polyansky, Aviad Schnapp, Nadia Wattad, Dorit Shmueli, Daphna Golan, F. Xavier Castellanos

Open Access Research

Touch and olfaction/taste differentiate children carrying a 16p11.2 deletion from children with ASD

Joana Maria Almeida Osório, Borja Rodríguez-Herreros, David Romascano, Vincent Junod, Aline Habegger, Aurélie Pain, Sonia Richetin, Paola Yu, Bertrand Isidor, Lionel Van Maldergem, Linda Pons, Sabine Manificat, Nadia Chabane, Marine Jequier Gygax, Anne Manuela Maillard

Open Access Research

Modified CBT for social anxiety and social functioning in young adults with autism spectrum disorder

Emily R. Bemmer, Kelsie A. Boulton, Emma E. Thomas, Ben Larke, Suncica Lah, Ian B. Hickie, Adam J. Guastella

Open Access Research

Analysis of common genetic variation and rare CNVs in the Australian Autism Biobank

Chloe X. Yap, Gail A. Alvares, Anjali K. Henders, Tian Lin, Leanne Wallace, Alaina Farrelly, Tiana McLaren, Jolene Berry, Anna A. E. Vinkhuyzen, Maciej Trzaskowski, Jian Zeng, Yuanhao Yang, Dominique Cleary, Rachel Grove, Claire Hafekost, Alexis Harun, Helen Holdsworth, Rachel Jellett, Feroza Khan, Lauren Lawson, Jodie Leslie, Mira Levis Frenk, Anne Masi, Nisha E. Mathew, Melanie Muniandy, Michaela Nothard, Peter M. Visscher, Paul A. Dawson, Cheryl Dissanayake, Valsamma Eapen, Helen S. Heussler, Andrew J. O. Whitehouse, Naomi R. Wray, Jacob Gratten

Open Access Research

Is social camouflaging associated with anxiety and depression in autistic adults?

Laura Hull, Lily Levy, Meng-Chuan Lai, K. V. Petrides, Simon Baron-Cohen, Carrie Allison, Paula Smith, Will Mandy

Open Access Research

Modulation of atypical brain activation during executive functioning in autism: a pharmacological MRI study of tianeptine

Robert H. Wichers, James L. Findon, Auke Jelsma, Vincent Giampietro, Vladimira Stoencheva, Dene M. Robertson, Clodagh M. Murphy, Sarah Blainey, Grainne McAlonan, Christine Ecker, Katya Rubia, Declan G. M. Murphy, Eileen M. Daly

Open Access Research

Oxytocin-induced increase in N,N-dimethylglycine and time course of changes in oxytocin efficacy for autism social core symptoms

Yasuhiko Kato, Hitoshi Kuwabara, Takashi Okada, Toshio Munesue, Seico Benner, Miho Kuroda, Masaki Kojima, Walid Yassin, Yosuke Eriguchi, Yosuke Kameno, Chihiro Murayama, Tomoko Nishimura, Kenji Tsuchiya, Kiyoto Kasai, Norio Ozaki, Hirotaka Kosaka, Hidenori Yamasue

Open Access Research

Distinct, dosage-sensitive requirements for the autism-associated factor CHD8 during cortical development

Shaun Hurley, Conor Mohan, Philipp Suetterlin, Robert Ellingford, Kimberley L. H. Riegman, Jacob Ellegood, Angela Caruso, Caterina Michetti, Olivier Brock, Romy Evans, Fabrizio Rudari, Alessio Delogu, Maria Luisa Scattoni, Jason P. Lerch, Cathy Fernandes, M. Albert Basson

Open Access Research

Sleep disorders in rare genetic syndromes: a meta-analysis of prevalence and profile

Georgie Agar, Chloe Brown, Daniel Sutherland, Sean Coulborn, Chris Oliver, Caroline Richards

Open Access Research

Towards robust and replicable sex differences in the intrinsic brain function of autism

Dorothea L. Floris, José O. A. Filho, Meng-Chuan Lai, Steve Giavasis, Marianne Oldehinkel, Maarten Mennes, Tony Charman, Julian Tillmann, Guillaume Dumas, Christine Ecker, Flavio Dell’Acqua, Tobias Banaschewski, Carolin Moessnang, Simon Baron-Cohen, Sarah Durston, Eva Loth, Declan G. M. Murphy, Jan K. Buitelaar, Christian F. Beckmann, Michael P. Milham, Adriana Di Martino

Open Access Research

Evaluating the latent structure of the non-social domain of autism in autistic adults

Rachel Grove, Sander Begeer, Anke M. Scheeren, Ricarda F. Weiland, Rosa A. Hoekstra

Open Access Research

Hippocampal neurons isolated from rats subjected to the valproic acid model mimic in vivo synaptic pattern: evidence of neuronal priming during early development in autism spectrum disorders

Marianela Evelyn Traetta, Martín Gabriel Codagnone, Nonthué Alejandra Uccelli, Alberto Javier Ramos, Sandra Zárate, Analía Reinés

Open Access Review

A profile and review of findings from the Early Markers for Autism study: unique contributions from a population-based case–control study in California

Kristen Lyall, Jennifer L. Ames, Michelle Pearl, Michela Traglia, Lauren A. Weiss, Gayle C. Windham, Martin Kharrazi, Cathleen K. Yoshida, Robert Yolken, Heather E. Volk, Paul Ashwood, Judy Van de Water, Lisa A. Croen

Open Access Research

Neuroanatomy and behavior in mice with a haploinsufficiency of AT-rich interactive domain 1B (ARID1B) throughout development

J. Ellegood, S. P. Petkova, A. Kinman, L. R. Qiu, A. Adhikari, A. A. Wade, D. Fernandes, Z. Lindenmaier, A. Creighton, L. M. J. Nutter, A. S. Nord, J. L. Silverman, J. P. Lerch

Open Access Research

Tactile cortical responses and association with tactile reactivity in young children on the autism spectrum

Svenja Espenhahn, Kate J. Godfrey, Sakshi Kaur, Maia Ross, Niloy Nath, Olesya Dmitrieva, Carly McMorris, Filomeno Cortese, Charlene Wright, Kara Murias, Deborah Dewey, Andrea B. Protzner, Adam McCrimmon, Signe Bray, Ashley D. Harris

Open Access Research

Imitation and recognition of facial emotions in autism: a computer vision approach

Hanna Drimalla, Irina Baskow, Behnoush Behnia, Stefan Roepke, Isabel Dziobek

Open Access Research

Shifted phase of EEG cross-frequency coupling in individuals with Phelan-McDermid syndrome

Michael. G. Mariscal, Elizabeth Berry-Kravis, Joseph D. Buxbaum, Lauren E. Ethridge, Rajna Filip-Dhima, Jennifer H. Foss-Feig, Alexander Kolevzon, Meera. E. Modi, Matthew W. Mosconi, Charles A. Nelson, Craig M. Powell, Paige M. Siper, Latha Soorya, Andrew Thaliath, Audrey Thurm, Bo Zhang, Mustafa Sahin, April R. Levin

Open Access Research

Extremely preterm birth and autistic traits in young adulthood: the EPICure study

Helen O’Reilly, Yanyan Ni, Samantha Johnson, Dieter Wolke, Neil Marlow

Open Access Research

An investigation of the diet, exercise, sleep, BMI, and health outcomes of autistic adults

Elizabeth Weir, Carrie Allison, Ken K. Ong, Simon Baron-Cohen

Open Access Research

Examining a stepped-care telehealth program for parents of young children with autism: a proof-of-concept trial

Allison L. Wainer, Zachary E. Arnold, Caroline Leonczyk, Latha Valluripalli Soorya

Open Access Correction

Correction to: Chd8 haploinsufficiency impairs early brain development and protein homeostasis later in life

Jessica A. Jiménez, Travis S. Ptacek, Alex H. Tuttle, Ralf S. Schmid, Sheryl S. Moy, Jeremy M. Simon, Mark J. Zylka

Open Access Research

Bayonet-shaped language development in autism with regression: a retrospective study

David Gagnon, Abderrahim Zeribi, Élise Douard, Valérie Courchesne, Borja Rodríguez-Herreros, Guillaume Huguet, Sébastien Jacquemont, Mor Absa Loum, Laurent Mottron

Open Access Research

Prospective and detailed behavioral phenotyping in DDX3X syndrome

Lara Tang, Tess Levy, Sylvia Guillory, Danielle Halpern, Jessica Zweifach, Ivy Giserman-Kiss, Jennifer H. Foss-Feig, Yitzchak Frank, Reymundo Lozano, Puneet Belani, Christina Layton, Bonnie Lerman, Emanuel Frowner, Michael S. Breen, Silvia De Rubeis, Ana Kostic, Alexander Kolevzon, Joseph D. Buxbaum, Paige M. Siper, Dorothy E. Grice

Open Access Research

The Comprehensive Autistic Trait Inventory (CATI): development and validation of a new measure of autistic traits in the general population

Michael C. W. English, Gilles E. Gignac, Troy A. W. Visser, Andrew J. O. Whitehouse, James T. Enns, Murray T. Maybery

Open Access Research

Randomized controlled trial of sulforaphane and metabolite discovery in children with Autism Spectrum Disorder

Andrew W. Zimmerman, Kanwaljit Singh, Susan L. Connors, Hua Liu, Anita A. Panjwani, Li-Ching Lee, Eileen Diggins, Ann Foley, Stepan Melnyk, Indrapal N. Singh, S. Jill James, Richard E. Frye, Jed W. Fahey

Open Access Research

Using the big data approach to clarify the structure of restricted and repetitive behaviors across the most commonly used autism spectrum disorder measures

Mirko Uljarević, Booil Jo, Thomas W. Frazier, Lawrence Scahill, Eric A. Youngstrom, Antonio Y. Hardan

Open Access Research

Psychometric validation and refinement of the Interoception Sensory Questionnaire (ISQ) in adolescents and adults on the autism spectrum

Evan Suzman, Zachary J. Williams, Jacob I. Feldman, Michelle Failla, Carissa J. Cascio, Mark T. Wallace, Maria Niarchou, James S. Sutcliffe, Ericka Wodka, Tiffany G. Woynaroski

Open Access Research

Genetic and morphological estimates of androgen exposure predict social deficits in multiple neurodevelopmental disorder cohorts

Brooke G. McKenna, Yongchao Huang, Kévin Vervier, Dabney Hofammann, Mary Cafferata, Seima Al-Momani, Florencia Lowenthal, Angela Zhang, Jin-Young Koh, Savantha Thenuwara, Leo Brueggeman, Ethan Bahl, Tanner Koomar, Natalie Pottschmidt, Taylor Kalmus, Lucas Casten, Taylor R. Thomas, Jacob J. Michaelson

Open Access Correction

Correction to: Randomized controlled trial of sulforaphane and metabolite discovery in children with Autism Spectrum Disorder

Andrew W. Zimmerman, Kanwaljit Singh, Susan L. Connors, Hua Liu, Anita A. Panjwani, Li‑Ching Lee, Eileen Diggins, Ann Foley, Stepan Melnyk, Indrapal N. Singh, S. Jill James, Richard E. Frye, Jed W. Fahey

Open Access Research

Autism symptoms in anorexia nervosa: a comparative study with females with autism spectrum disorder

Jess Kerr-Gaffney, Hannah Hayward, Emily J. H. Jones, Daniel Halls, Declan Murphy, Kate Tchanturia

Open Access Research

Neurite orientation dispersion and density imaging reveals white matter microstructural alterations in adults with autism

Christina Andica, Koji Kamagata, Eiji Kirino, Wataru Uchida, Ryusuke Irie, Syo Murata, Shigeki Aoki

Open Access Research

Modulation of striatal functional connectivity differences in adults with and without autism spectrum disorder in a single-dose randomized trial of cannabidivarin

Charlotte M. Pretzsch, Dorothea L. Floris, Bogdan Voinescu, Malka Elsahib, Maria A. Mendez, Robert Wichers, Laura Ajram, Glynis Ivin, Martin Heasman, Elise Pretzsch, Steven Williams, Declan G. M. Murphy, Eileen Daly, Gráinne M. McAlonan

Open Access Research

Autism-associated biomarkers: test–retest reliability and relationship to quantitative social trait variation in rhesus monkeys

Ozge Oztan, Catherine F. Talbot, Emanuela Argilli, Alyssa C. Maness, Sierra M. Simmons, Noreen Mohsin, Laura A. Del Rosso, Joseph P. Garner, Elliott H. Sherr, John P. Capitanio, Karen J. Parker

Open Access Research

Maternal steroid levels and the autistic traits of the mother and infant

A. Tsompanidis, E. Aydin, E. Padaigaitė, G. Richards, C. Allison, G. Hackett, T. Austin, R. Holt, S. Baron-Cohen

Open Access Research

Initial action output and feedback-guided motor behaviors in autism spectrum disorder

Kathryn E. Unruh, Walker S. McKinney, Erin K. Bojanek, Kandace K. Fleming, John A. Sweeney, Matthew W. Mosconi

Open Access Research

MEK inhibition ameliorates social behavior phenotypes in a Spred1 knockout mouse model for RASopathy disorders

Sarah C. Borrie, Ellen Plasschaert, Zsuzsanna Callaerts-Vegh, Akihiko Yoshimura, Rudi D’Hooge, Ype Elgersma, Steven A. Kushner, Eric Legius, Hilde Brems

Open Access Research

Abnormal sleep physiology in children with 15q11.2-13.1 duplication (Dup15q) syndrome

Vidya Saravanapandian, Divya Nadkarni, Sheng-Hsiou Hsu, Shaun A. Hussain, Kiran Maski, Peyman Golshani, Christopher S. Colwell, Saravanavel Balasubramanian, Amos Dixon, Daniel H. Geschwind, Shafali S. Jeste

Open Access Methodology

The Monash Autism-ADHD genetics and neurodevelopment (MAGNET) project design and methodologies: a dimensional approach to understanding neurobiological and genetic aetiology

Rachael Knott, Beth P. Johnson, Jeggan Tiego, Olivia Mellahn, Amy Finlay, Kathryn Kallady, Maria Kouspos, Vishnu Priya Mohanakumar Sindhu, Ziarih Hawi, Aurina Arnatkeviciute, Tracey Chau, Dalia Maron, Emily-Clare Mercieca, Kirsten Furley, Katrina Harris, Katrina Williams, Alexandra Ure, Alex Fornito, Kylie Gray, David Coghill, Ann Nicholson, Dinh Phung, Eva Loth, Luke Mason, Declan Murphy, Jan Buitelaar, Mark A. Bellgrove

Open Access Research

Non-verbal IQ and change in restricted and repetitive behavior throughout childhood in autism: a longitudinal study using the Autism Diagnostic Interview-Revised

V. Courchesne, R. Bedford, A. Pickles, E. Duku, C. Kerns, P. Mirenda, T. Bennett, S. Georgiades, I. M. Smith, W. J. Ungar, T. Vaillancourt, A. Zaidman-Zait, L. Zwaigenbaum, P. Szatmari, M. Elsabbagh

Open Access Correction

Correction to: Biological motion perception in autism spectrum disorder: a meta-analysis

Greta Krasimirova Todorova, Rosalind Elizabeth Mcbean Hatton, Frank Earl Pollick

Open Access Research

Insulin-like growth factor-2 does not improve behavioral deficits in mouse and rat models of Angelman Syndrome

Elizabeth L. Berg, Stela P. Petkova, Heather A. Born, Anna Adhikari, Anne E. Anderson, Jill L. Silverman

Open Access Research

Fever during pregnancy as a risk factor for neurodevelopmental disorders: results from a systematic review and meta-analysis

Stephanie Antoun, Pierre Ellul, Hugo Peyre, Michelle Rosenzwajg, Pierre Gressens, David Klatzmann, Richard Delorme

Open Access Research

Individuals with FOXP1 syndrome present with a complex neurobehavioral profile with high rates of ADHD, anxiety, repetitive behaviors, and sensory symptoms

M. Pilar Trelles, Tess Levy, Bonnie Lerman, Paige Siper, Reymundo Lozano, Danielle Halpern, Hannah Walker, Jessica Zweifach, Yitzchak Frank, Jennifer Foss-Feig, Alexander Kolevzon, Joseph Buxbaum

Open Access Research

A randomized controlled trial of intranasal oxytocin in Phelan-McDermid syndrome

J. Fastman, J. Foss-Feig, Y. Frank, D. Halpern, H. Harony-Nicolas, C. Layton, S. Sandin, P. Siper, L. Tang, P. Trelles, J. Zweifach, J. D. Buxbaum, A. Kolevzon

Open Access Research

Affect and gaze responses during an Emotion-Evoking Task in infants at an increased likelihood for autism spectrum disorder

Lori-Ann R. Sacrey, Lonnie Zwaigenbaum, Jessica A. Brian, Isabel M. Smith, Vickie Armstrong, Sarah Raza, Tracy Vaillancourt, Louis A. Schmidt

Open Access Research

Prediction learning in adults with autism and its molecular correlates

Laurie-Anne Sapey-Triomphe, Joke Temmerman, Nicolaas A. J. Puts, Johan Wagemans

Open Access Research

Prevalence and phenotypic impact of rare potentially damaging variants in autism spectrum disorder

Behrang Mahjani, Silvia De Rubeis, Christina Gustavsson Mahjani, Maureen Mulhern, Xinyi Xu, Lambertus Klei, F. Kyle Satterstrom, Jack Fu, Michael E. Talkowski, Abraham Reichenberg, Sven Sandin, Christina M. Hultman, Dorothy E. Grice, Kathryn Roeder, Bernie Devlin, Joseph D. Buxbaum

Open Access Research

How rare and common risk variation jointly affect liability for autism spectrum disorder

Lambertus Klei, Lora Lee McClain, Behrang Mahjani, Klea Panayidou, Silvia De Rubeis, Anna-Carin Säll Grahnat, Gun Karlsson, Yangyi Lu, Nadine Melhem, Xinyi Xu, Abraham Reichenberg, Sven Sandin, Christina M. Hultman, Joseph D. Buxbaum, Kathryn Roeder, Bernie Devlin

Open Access Research

Exploring sensory phenotypes in autism spectrum disorder

Nichole E. Scheerer, Kristina Curcin, Bobby Stojanoski, Evdokia Anagnostou, Rob Nicolson, Elizabeth Kelley, Stelios Georgiades, Xudong Liu, Ryan A. Stevenson

Open Access Research

Regulatory T lymphocytes/Th17 lymphocytes imbalance in autism spectrum disorders: evidence from a meta-analysis

Pierre Ellul, Michelle Rosenzwajg, Hugo Peyre, Gwladys Fourcade, Encarnita Mariotti-Ferrandiz, Vincent Trebossen, David Klatzmann, Richard Delorme

Open Access Research

De novo variants in CACNA1E found in patients with intellectual disability, developmental regression and social cognition deficit but no seizures

Beryl Royer-Bertrand, Marine Jequier Gygax, Katarina Cisarova, Jill A. Rosenfeld, Jennifer A. Bassetti, Oana Moldovan, Emily O’Heir, Lindsay C. Burrage, Jake Allen, Lisa T. Emrick, Emma Eastman, Camille Kumps, Safdar Abbas, Geraldine Van Winckel, Nadia Chabane, Elaine H. Zackai, Sebastien Lebon, Beth Keena, Elizabeth J. Bhoj, Muhammad Umair, Dong Li, Kirsten A. Donald, Andrea Superti-Furga

Open Access Correction

Correction to: The Comprehensive Autistic Trait Inventory (CATI): development and validation of a new measure of autistic traits in the general population

Michael C. W. English, Gilles E. Gignac, Troy A. W. Visser, Andrew J. O. Whitehouse, James T. Enns, Murray T. Maybery

Open Access Research

Visual attention and inhibitory control in children, teenagers and adults with autism without intellectual disability: results of oculomotor tasks from a 2-year longitudinal follow-up study (InFoR)

Anouck Amestoy, Etienne Guillaud, Giulia Bucchioni, Tiziana Zalla, Daniel Umbricht, Christopher Chatham, Lorraine Murtagh, Josselin Houenou, Richard Delorme, Myriam Ly-Le Moal, Marion Leboyer, Manuel Bouvard, Jean-René Cazalets

Open Access Research

Childhood diagnoses in individuals identified as autistics in adulthood

Eya-Mist Rødgaard, Kristian Jensen, Kamilla Woznica Miskowiak, Laurent Mottron

Open Access Research

Preference for biological motion is reduced in ASD: implications for clinical trials and the search for biomarkers

L. Mason, F. Shic, T. Falck-Ytter, B. Chakrabarti, T. Charman, E. Loth, J. Tillmann, T. Banaschewski, S. Baron-Cohen, S. Bölte, J. Buitelaar, S. Durston, B. Oranje, A. M. Persico, C. Beckmann, T. Bougeron, F. Dell’Acqua, C. Ecker, C. Moessnang, D. Murphy, M. H. Johnson, E. J. H. Jones, Jumana Ahmad, Sara Ambrosino, Sarah Baumeister, Carsten Bours, Michael Brammer, Daniel Brandeis, Claudia Brogna, Yvette de Bruijn, Chris Chatham, Ineke Cornelissen, Daisy Crawley, Guillaume Dumas, Jessica Faulkner, Vincent Frouin, Pilar Garcés, David Goyard, Lindsay Ham, Joerg Hipp, Rosemary Holt, Meng-Chuan Lai, Xavier Liogier D’ardhuy, Michael V. Lombardo, David J. Lythgoe, René Mandl, Andre Marquand, Maarten Mennes, Andreas Meyer-Lindenberg, Nico Bast, Bethany Oakley, Laurence O’Dwyer, Marianne Oldehinkel, Gahan Pandina, Barbara Ruggeri, Amber Ruigrok, Jessica Sabet, Roberto Sacco, Antonia San José Cáceres, Emily Simonoff, Will Spooren, Roberto Toro, Heike Tost, Jack Waldman, Steve C. R. Williams, Caroline Wooldridge, Marcel P. Zwiers