Skip to main content

2018 | OriginalPaper | Buchkapitel

10. Neurologische Komplikationen entzündlicher Darmerkrankungen

verfasst von : Oliver Bachmann, Natascha Wehnert

Erschienen in: Autoimmunerkrankungen in der Neurologie

Verlag: Springer Berlin Heidelberg

Zusammenfassung

Mit einigen entzündlichen Darmerkrankungen sind neurologische Symptome assoziiert, die zum Teil das Krankheitsbild wesentlich mit charakterisieren und die Diagnosestellung erleichtern oder überhaupt erst ermöglichen. In anderen Fällen ist die Verknüpfung schwer zu belegen und läuft somit Gefahr, übersehen zu werden – insbesondere, wenn neurologische Symptome den intestinalen vorausgehen oder umgekehrt bzw. andere mögliche Ursachen bestehen. Neurologische Komplikationen sind sowohl bei den chronisch entzündlichen Darmerkrankungen im engeren Sinne als auch bei der Zöliakie und auch beim durch grampositive Bakterien verursachten Morbus Whipple beschrieben. Dieses Kapitel fasst die Literatur zu neurologischen Komplikationen der genannten entzündlichen Darmerkrankungen hinsichtlich ihrer Charakteristika, Diagnostik, Abgrenzung anderer Ursachen und therapeutischer Strategien zusammen.
Literatur
Zurück zum Zitat Addolorato G, Di Giuda D, De Rossi G, Valenza V, Domenicali M, Caputo F et al (2004) Regional cerebral hypoperfusion in patients with celiac disease. Am J Med 116(5):312–317CrossRefPubMed Addolorato G, Di Giuda D, De Rossi G, Valenza V, Domenicali M, Caputo F et al (2004) Regional cerebral hypoperfusion in patients with celiac disease. Am J Med 116(5):312–317CrossRefPubMed
Zurück zum Zitat Akbayir N, Calis AB, Alkim C, Sokmen HM, Erdem L, Ozbal A et al (2005) Sensorineural hearing loss in patients with inflammatory bowel disease: a subclinical extraintestinal manifestation. Dig Dis Sci 50(10):1938–1945CrossRefPubMed Akbayir N, Calis AB, Alkim C, Sokmen HM, Erdem L, Ozbal A et al (2005) Sensorineural hearing loss in patients with inflammatory bowel disease: a subclinical extraintestinal manifestation. Dig Dis Sci 50(10):1938–1945CrossRefPubMed
Zurück zum Zitat van Assche G, Van Ranst M, Sciot R, Dubois B, Vermeire S, Noman M et al (2005) Progressive multifocal leukoencephalopathy after natalizumab therapy for Crohn‘s disease. New Engl J Med 353(4):362–368CrossRefPubMed van Assche G, Van Ranst M, Sciot R, Dubois B, Vermeire S, Noman M et al (2005) Progressive multifocal leukoencephalopathy after natalizumab therapy for Crohn‘s disease. New Engl J Med 353(4):362–368CrossRefPubMed
Zurück zum Zitat Bachmann O, Langer F, Rademacher J (2010) Pulmonary manifestations of inflammatory bowel disease. Der Internist 51(Suppl 1):264–268CrossRefPubMed Bachmann O, Langer F, Rademacher J (2010) Pulmonary manifestations of inflammatory bowel disease. Der Internist 51(Suppl 1):264–268CrossRefPubMed
Zurück zum Zitat Barbado FJ, Vazquez JJ, Gil A, Ortiz Vazquez J (1980) Vasculitis and ulcerative colitis. Gastroenterol 79(2):417–418 Barbado FJ, Vazquez JJ, Gil A, Ortiz Vazquez J (1980) Vasculitis and ulcerative colitis. Gastroenterol 79(2):417–418
Zurück zum Zitat Baron BW, Jeon HR, Glunz C, Peterson A, Cohen R, Hanauer S et al (2002) First two patients with ulcerative colitis who developed classical thrombotic thrombocytopenic purpura successfully treated with medical therapy and plasma exchange. J Clin Apheresis 17(4):204–206CrossRefPubMed Baron BW, Jeon HR, Glunz C, Peterson A, Cohen R, Hanauer S et al (2002) First two patients with ulcerative colitis who developed classical thrombotic thrombocytopenic purpura successfully treated with medical therapy and plasma exchange. J Clin Apheresis 17(4):204–206CrossRefPubMed
Zurück zum Zitat Baumgart DC, Sandborn WJ (2007) Inflammatory bowel disease: clinical aspects and established and evolving therapies. Lancet 369(9573):1641–1657CrossRefPubMed Baumgart DC, Sandborn WJ (2007) Inflammatory bowel disease: clinical aspects and established and evolving therapies. Lancet 369(9573):1641–1657CrossRefPubMed
Zurück zum Zitat Berden JH, Hoitsma AJ, Merx JL, Keyser A (1985) Severe central-nervous-system toxicity associated with cyclosporin. Lancet 1(8422):219–220CrossRefPubMed Berden JH, Hoitsma AJ, Merx JL, Keyser A (1985) Severe central-nervous-system toxicity associated with cyclosporin. Lancet 1(8422):219–220CrossRefPubMed
Zurück zum Zitat Bernstein CN, Wajda A, Blanchard JF (2005) The clustering of other chronic inflammatory diseases in inflammatory bowel disease: a population-based study. Gastroenterol 129(3):827–836CrossRef Bernstein CN, Wajda A, Blanchard JF (2005) The clustering of other chronic inflammatory diseases in inflammatory bowel disease: a population-based study. Gastroenterol 129(3):827–836CrossRef
Zurück zum Zitat Burk K, Bosch S, Muller CA, Melms A, Zuhlke C, Stern M et al (2001a) Sporadic cerebellar ataxia associated with gluten sensitivity. Brain: J Neurol 124(5):1013–1019CrossRef Burk K, Bosch S, Muller CA, Melms A, Zuhlke C, Stern M et al (2001a) Sporadic cerebellar ataxia associated with gluten sensitivity. Brain: J Neurol 124(5):1013–1019CrossRef
Zurück zum Zitat Burk K, Melms A, Schulz JB, Dichgans J (2001b) Effectiveness of intravenous immunoglobin therapy in cerebellar ataxia associated with gluten sensitivity. Ann Neurol 50(6):827–828CrossRefPubMed Burk K, Melms A, Schulz JB, Dichgans J (2001b) Effectiveness of intravenous immunoglobin therapy in cerebellar ataxia associated with gluten sensitivity. Ann Neurol 50(6):827–828CrossRefPubMed
Zurück zum Zitat Carmona MA, Jaume Anselmi F, Ramirez Rivera J (2000) Cerebral thrombosis and vasculitis: an uncommon complication of ulcerative colitis. Bol Asoc Med P R 92(1–3):9–11PubMed Carmona MA, Jaume Anselmi F, Ramirez Rivera J (2000) Cerebral thrombosis and vasculitis: an uncommon complication of ulcerative colitis. Bol Asoc Med P R 92(1–3):9–11PubMed
Zurück zum Zitat Colombel JF, Loftus EV Jr, Tremaine WJ, Egan LJ, Harmsen WS, Schleck CD et al (2004) The safety profile of infliximab in patients with Crohn’s disease: the Mayo clinic experience in 500 patients. Gastroenterol 126(1):19–31CrossRef Colombel JF, Loftus EV Jr, Tremaine WJ, Egan LJ, Harmsen WS, Schleck CD et al (2004) The safety profile of infliximab in patients with Crohn’s disease: the Mayo clinic experience in 500 patients. Gastroenterol 126(1):19–31CrossRef
Zurück zum Zitat Cortese I, Chaudhry V, So YT, Cantor F, Cornblath DR, Rae-Grant A (2011) Evidence-based guideline update: plasmapheresis in neurologic disorders: report of the therapeutics and technology assessment subcommittee of the American academy of Neurology. Neurol 76(3):294–300CrossRef Cortese I, Chaudhry V, So YT, Cantor F, Cornblath DR, Rae-Grant A (2011) Evidence-based guideline update: plasmapheresis in neurologic disorders: report of the therapeutics and technology assessment subcommittee of the American academy of Neurology. Neurol 76(3):294–300CrossRef
Zurück zum Zitat Dimitrova AK, Ungaro RC, Lebwohl B, Lewis SK, Tennyson CA, Green MW et al (2013) Prevalence of migraine in patients with celiac disease and inflammatory bowel disease. Headache 53(2):344–355CrossRefPubMed Dimitrova AK, Ungaro RC, Lebwohl B, Lewis SK, Tennyson CA, Green MW et al (2013) Prevalence of migraine in patients with celiac disease and inflammatory bowel disease. Headache 53(2):344–355CrossRefPubMed
Zurück zum Zitat Druschky A, Heckmann J, Engelhardt A, Neundorfer (1996) Myositis – a rare complication of Crohn disease. Fortschr Neurol Psychiatr 64(10):422–424CrossRefPubMed Druschky A, Heckmann J, Engelhardt A, Neundorfer (1996) Myositis – a rare complication of Crohn disease. Fortschr Neurol Psychiatr 64(10):422–424CrossRefPubMed
Zurück zum Zitat Duffy LF, Daum F, Fisher SE, Selman J, Vishnubhakat SM, Aiges HW et al (1985) Peripheral neuropathy in Crohn’s disease patients treated with metronidazole. Gastroenterol 88(3):681–684CrossRef Duffy LF, Daum F, Fisher SE, Selman J, Vishnubhakat SM, Aiges HW et al (1985) Peripheral neuropathy in Crohn’s disease patients treated with metronidazole. Gastroenterol 88(3):681–684CrossRef
Zurück zum Zitat Elsehety A, Bertorini TE (1997) Neurologic and neuropsychiatric complications of Crohn‘s disease. S Med J 90(6):606–610CrossRef Elsehety A, Bertorini TE (1997) Neurologic and neuropsychiatric complications of Crohn‘s disease. S Med J 90(6):606–610CrossRef
Zurück zum Zitat Felber J, Aust D, Baas S, Bischoff S, Blaker H, Daum S et al (2014) Results of a S2k-Consensus Conference of the German Society of Gastroenterolgy, Digestive- and Metabolic Diseases (DGVS) in conjunction with the German Coeliac Society (DZG) regarding coeliac disease, wheat allergy and wheat sensitivity. Z Gastroenterol 52(7):711–743CrossRefPubMed Felber J, Aust D, Baas S, Bischoff S, Blaker H, Daum S et al (2014) Results of a S2k-Consensus Conference of the German Society of Gastroenterolgy, Digestive- and Metabolic Diseases (DGVS) in conjunction with the German Coeliac Society (DZG) regarding coeliac disease, wheat allergy and wheat sensitivity. Z Gastroenterol 52(7):711–743CrossRefPubMed
Zurück zum Zitat Ferrante M, de Hertogh G, Hlavaty T, D‘Haens G, Penninckx F, D‘Hoore A et al (2006) The value of myenteric plexitis to predict early postoperative Crohn’s disease recurrence. Gastroenterol 130(6):1595–1606CrossRef Ferrante M, de Hertogh G, Hlavaty T, D‘Haens G, Penninckx F, D‘Hoore A et al (2006) The value of myenteric plexitis to predict early postoperative Crohn’s disease recurrence. Gastroenterol 130(6):1595–1606CrossRef
Zurück zum Zitat Ferro JM, Oliveira S (2014) Neurologic manifestations of gastrointestinal and liver diseases. Curr Neurol Neurosci Rep 14(10):487CrossRefPubMed Ferro JM, Oliveira S (2014) Neurologic manifestations of gastrointestinal and liver diseases. Curr Neurol Neurosci Rep 14(10):487CrossRefPubMed
Zurück zum Zitat Feurle GE, Moos V, Schneider T, Fenollar F, Raoult D (2012) The combination of chloroquine and minocycline, a therapeutic option in cerebrospinal infection of Whipple‘s disease refractory to treatment with ceftriaxone, meropenem and co-trimoxazole. J Antimicrob Chemother 67(5):1295–1296CrossRefPubMed Feurle GE, Moos V, Schneider T, Fenollar F, Raoult D (2012) The combination of chloroquine and minocycline, a therapeutic option in cerebrospinal infection of Whipple‘s disease refractory to treatment with ceftriaxone, meropenem and co-trimoxazole. J Antimicrob Chemother 67(5):1295–1296CrossRefPubMed
Zurück zum Zitat Figueroa JJ, Loftus EV Jr, Harmsen WS, Dyck PJ, Klein CJ (2013) Peripheral neuropathy incidence in inflammatory bowel disease: a population-based study. Neurol 80(18):1693–1697CrossRef Figueroa JJ, Loftus EV Jr, Harmsen WS, Dyck PJ, Klein CJ (2013) Peripheral neuropathy incidence in inflammatory bowel disease: a population-based study. Neurol 80(18):1693–1697CrossRef
Zurück zum Zitat Final report on the safety assessment of Ricinus (2007) Communis (Castor) Seed Oil, Hydrogenated Castor Oil, Glyceryl Ricinoleate, Glyceryl Ricinoleate SE, Ricinoleic Acid, Potassium Ricinoleate, Sodium Ricinoleate, Zinc Ricinoleate, Cetyl Ricinoleate, Ethyl Ricinoleate, Glycol Ricinoleate, Isopropyl Ricinoleate, Methyl Ricinoleate, and Octyldodecyl Ricinoleate. Int J Toxicol 26(Suppl 3):31–77 Final report on the safety assessment of Ricinus (2007) Communis (Castor) Seed Oil, Hydrogenated Castor Oil, Glyceryl Ricinoleate, Glyceryl Ricinoleate SE, Ricinoleic Acid, Potassium Ricinoleate, Sodium Ricinoleate, Zinc Ricinoleate, Cetyl Ricinoleate, Ethyl Ricinoleate, Glycol Ricinoleate, Isopropyl Ricinoleate, Methyl Ricinoleate, and Octyldodecyl Ricinoleate. Int J Toxicol 26(Suppl 3):31–77
Zurück zum Zitat Finnie IA, Shields R, Sutton R, Donnelly R, Morris AI (1994) Crohn‘s disease and myasthenia gravis: a possible role for thymectomy. Gut 35(2):278–279CrossRefPubMedPubMedCentral Finnie IA, Shields R, Sutton R, Donnelly R, Morris AI (1994) Crohn‘s disease and myasthenia gravis: a possible role for thymectomy. Gut 35(2):278–279CrossRefPubMedPubMedCentral
Zurück zum Zitat Freeman HJ (2008) Neurological disorders in adult celiac disease. Can J Gastroenterol = J Can gastroenterol 22(11):909–911CrossRef Freeman HJ (2008) Neurological disorders in adult celiac disease. Can J Gastroenterol = J Can gastroenterol 22(11):909–911CrossRef
Zurück zum Zitat Galldiks N, Burghaus L, Vollmar S, Cizek J, Impekoven P, Thomas A et al (2004) Novel neuroimaging findings in a patient with cerebral Whipple‘s disease: a magnetic resonance imaging and positron emission tomography study. J Neuroimaging 4(4):372–376CrossRef Galldiks N, Burghaus L, Vollmar S, Cizek J, Impekoven P, Thomas A et al (2004) Novel neuroimaging findings in a patient with cerebral Whipple‘s disease: a magnetic resonance imaging and positron emission tomography study. J Neuroimaging 4(4):372–376CrossRef
Zurück zum Zitat Gelfenbeyn M, Goodkin R, Kliot M (2006) Sterile recurrent spinal epidural abscess in a patient with Crohn’s disease: a case report. Surg Neurol 65(2):178–184CrossRefPubMed Gelfenbeyn M, Goodkin R, Kliot M (2006) Sterile recurrent spinal epidural abscess in a patient with Crohn’s disease: a case report. Surg Neurol 65(2):178–184CrossRefPubMed
Zurück zum Zitat Gerard A, Sarrot-Reynauld F, Liozon E, Cathebras P, Besson G, Robin C et al (2002) Neurologic presentation of Whipple disease: report of 12 cases and review of the literature. Med 81(6):443–457CrossRef Gerard A, Sarrot-Reynauld F, Liozon E, Cathebras P, Besson G, Robin C et al (2002) Neurologic presentation of Whipple disease: report of 12 cases and review of the literature. Med 81(6):443–457CrossRef
Zurück zum Zitat Gobbele R, Reith W, Block F (2000) Cerebral vasculitis as a concomitant neurological illness in Crohn’s disease. Der Nervenarzt 71(4):299–304CrossRefPubMed Gobbele R, Reith W, Block F (2000) Cerebral vasculitis as a concomitant neurological illness in Crohn’s disease. Der Nervenarzt 71(4):299–304CrossRefPubMed
Zurück zum Zitat Gobbi G, Bouquet F, Greco L, Lambertini A, Tassinari CA, Ventura A et al (1992) Coeliac disease, epilepsy, and cerebral calcifications. The Italian Working Group on Coeliac Disease and Epilepsy. Lancet 340(8817):439–443CrossRefPubMed Gobbi G, Bouquet F, Greco L, Lambertini A, Tassinari CA, Ventura A et al (1992) Coeliac disease, epilepsy, and cerebral calcifications. The Italian Working Group on Coeliac Disease and Epilepsy. Lancet 340(8817):439–443CrossRefPubMed
Zurück zum Zitat Gondim FA, Brannagan TH 3rd, Sander HW, Chin RL, Latov N (2005) Peripheral neuropathy in patients with inflammatory bowel disease. Brain: J Neurol 128(4):867–879CrossRef Gondim FA, Brannagan TH 3rd, Sander HW, Chin RL, Latov N (2005) Peripheral neuropathy in patients with inflammatory bowel disease. Brain: J Neurol 128(4):867–879CrossRef
Zurück zum Zitat Gower-Rousseau C, Reumaux D, Bellard M, Delecourt L, Ribet M, Colombel JF (1993) Remission of myasthenia gravis after proctocolectomy in a patient with ulcerative colitis. Am J Gastroenterol 88(7):1136–1138PubMed Gower-Rousseau C, Reumaux D, Bellard M, Delecourt L, Ribet M, Colombel JF (1993) Remission of myasthenia gravis after proctocolectomy in a patient with ulcerative colitis. Am J Gastroenterol 88(7):1136–1138PubMed
Zurück zum Zitat Gupta G, Gelfand JM, Lewis JD (2005) Increased risk for demyelinating diseases in patients with inflammatory bowel disease. Gastroenterol 129(3):819–826CrossRef Gupta G, Gelfand JM, Lewis JD (2005) Increased risk for demyelinating diseases in patients with inflammatory bowel disease. Gastroenterol 129(3):819–826CrossRef
Zurück zum Zitat Hadjivassiliou M, Aeschlimann P, Sanders DS, Maki M, Kaukinen K, Grunewald RA et al (2013) Transglutaminase 6 antibodies in the diagnosis of gluten ataxia. Neurol 80(19):1740–1745CrossRef Hadjivassiliou M, Aeschlimann P, Sanders DS, Maki M, Kaukinen K, Grunewald RA et al (2013) Transglutaminase 6 antibodies in the diagnosis of gluten ataxia. Neurol 80(19):1740–1745CrossRef
Zurück zum Zitat Hadjivassiliou M, Boscolo S, Davies-Jones GA, Grunewald RA, Not T, Sanders DS et al (2002) The humoral response in the pathogenesis of gluten ataxia. Neurol 58(8):1221–1226CrossRef Hadjivassiliou M, Boscolo S, Davies-Jones GA, Grunewald RA, Not T, Sanders DS et al (2002) The humoral response in the pathogenesis of gluten ataxia. Neurol 58(8):1221–1226CrossRef
Zurück zum Zitat Hadjivassiliou M, Davies-Jones GA, Sanders DS, Grunewald RA (2003) Dietary treatment of gluten ataxia. J Neurol Neurosurg Psychiatry 74(9):1221–1224CrossRefPubMedPubMedCentral Hadjivassiliou M, Davies-Jones GA, Sanders DS, Grunewald RA (2003) Dietary treatment of gluten ataxia. J Neurol Neurosurg Psychiatry 74(9):1221–1224CrossRefPubMedPubMedCentral
Zurück zum Zitat Hadjivassiliou M, Duker AP, Sanders DS (2014) Gluten-related neurologic dysfunction. Handb Clin Neurol 120:607–619CrossRefPubMed Hadjivassiliou M, Duker AP, Sanders DS (2014) Gluten-related neurologic dysfunction. Handb Clin Neurol 120:607–619CrossRefPubMed
Zurück zum Zitat Hadjivassiliou M, Sanders DD, Aeschlimann DP (2015) Gluten-related disorders: gluten ataxia. Dig Dis 33(2):264–268CrossRefPubMed Hadjivassiliou M, Sanders DD, Aeschlimann DP (2015) Gluten-related disorders: gluten ataxia. Dig Dis 33(2):264–268CrossRefPubMed
Zurück zum Zitat Hadjivassiliou M, Sanders DS, Grunewald RA, Woodroofe N, Boscolo S, Aeschlimann D (2010) Gluten sensitivity: from gut to brain. Lancet Neurol 9(3):318–330CrossRefPubMed Hadjivassiliou M, Sanders DS, Grunewald RA, Woodroofe N, Boscolo S, Aeschlimann D (2010) Gluten sensitivity: from gut to brain. Lancet Neurol 9(3):318–330CrossRefPubMed
Zurück zum Zitat Hadjivassiliou M, Sanders DS, Woodroofe N, Williamson C, Grunewald RA (2008) Gluten ataxia. Cerebellum 7(3):494–498CrossRefPubMed Hadjivassiliou M, Sanders DS, Woodroofe N, Williamson C, Grunewald RA (2008) Gluten ataxia. Cerebellum 7(3):494–498CrossRefPubMed
Zurück zum Zitat Hagel S, Epple HJ, Feurle GE, Kern WV, Lynen Jansen P, Malfertheiner P et al (2015) S2k-guideline gastrointestinal infectious diseases and Whipple’s disease. Z Gastroenterol 53(5):418–459CrossRefPubMed Hagel S, Epple HJ, Feurle GE, Kern WV, Lynen Jansen P, Malfertheiner P et al (2015) S2k-guideline gastrointestinal infectious diseases and Whipple’s disease. Z Gastroenterol 53(5):418–459CrossRefPubMed
Zurück zum Zitat von Herbay A, Ditton HJ, Schuhmacher F, Maiwald M (1997) Whipple‘s disease: staging and monitoring by cytology and polymerase chain reaction analysis of cerebrospinal fluid. Gastroenterol 113(2):434–441CrossRef von Herbay A, Ditton HJ, Schuhmacher F, Maiwald M (1997) Whipple‘s disease: staging and monitoring by cytology and polymerase chain reaction analysis of cerebrospinal fluid. Gastroenterol 113(2):434–441CrossRef
Zurück zum Zitat Heuer DK, Gager WE, Reeser FH (1982) Ischemic optic neuropathy associated with Crohn‘s disease. J Clin Neuroophthalmol 2(3):175–181PubMed Heuer DK, Gager WE, Reeser FH (1982) Ischemic optic neuropathy associated with Crohn‘s disease. J Clin Neuroophthalmol 2(3):175–181PubMed
Zurück zum Zitat Humbert P, Monnier G, Billerey C, Birgen C, Dupond JL (1989) Polyneuropathy: an unusual extraintestinal manifestation of Crohn’s disease. Acta Neurol Scand 80(4):301–306CrossRefPubMed Humbert P, Monnier G, Billerey C, Birgen C, Dupond JL (1989) Polyneuropathy: an unusual extraintestinal manifestation of Crohn’s disease. Acta Neurol Scand 80(4):301–306CrossRefPubMed
Zurück zum Zitat Hunt KA, Zhernakova A, Turner G, Heap GA, Franke L, Bruinenberg M et al (2008) Newly identified genetic risk variants for celiac disease related to the immune response. Nat Genet 40(4):395–402CrossRefPubMedPubMedCentral Hunt KA, Zhernakova A, Turner G, Heap GA, Franke L, Bruinenberg M et al (2008) Newly identified genetic risk variants for celiac disease related to the immune response. Nat Genet 40(4):395–402CrossRefPubMedPubMedCentral
Zurück zum Zitat Johns DR (1991) Cerebrovascular complications of inflammatory bowel disease. Am J Gastroenterol 86(3):367–370PubMed Johns DR (1991) Cerebrovascular complications of inflammatory bowel disease. Am J Gastroenterol 86(3):367–370PubMed
Zurück zum Zitat Karajeh MA, Hadjivassiliou M, Hurlstone P, Grundman MJ (2004) Neurological sequelae of Crohn’s disease: opportunity to study common etiological pathways. J Gastroenterol Hepatol 19(9):1093–1094CrossRefPubMed Karajeh MA, Hadjivassiliou M, Hurlstone P, Grundman MJ (2004) Neurological sequelae of Crohn’s disease: opportunity to study common etiological pathways. J Gastroenterol Hepatol 19(9):1093–1094CrossRefPubMed
Zurück zum Zitat Lagier JC, Fenollar F, Lepidi H, Giorgi R, Million M, Raoult D (2014) Treatment of classic Whipple‘s disease: from in vitro results to clinical outcome. J Antimicrob Chemother 69(1):219–227CrossRefPubMed Lagier JC, Fenollar F, Lepidi H, Giorgi R, Million M, Raoult D (2014) Treatment of classic Whipple‘s disease: from in vitro results to clinical outcome. J Antimicrob Chemother 69(1):219–227CrossRefPubMed
Zurück zum Zitat Lagier JC, Fenollar F, Lepidi H, Raoult D (2010) Failure and relapse after treatment with trimethoprim/sulfamethoxazole in classic Whipple‘s disease. J Antimicrob Chemother 65(9):2005–2012CrossRefPubMed Lagier JC, Fenollar F, Lepidi H, Raoult D (2010) Failure and relapse after treatment with trimethoprim/sulfamethoxazole in classic Whipple‘s disease. J Antimicrob Chemother 65(9):2005–2012CrossRefPubMed
Zurück zum Zitat Lam MC, Bressler B (2014) Vedolizumab for ulcerative colitis and Crohn‘s disease: results and implications of GEMINI studies. Immunother 6(9):963–971CrossRef Lam MC, Bressler B (2014) Vedolizumab for ulcerative colitis and Crohn‘s disease: results and implications of GEMINI studies. Immunother 6(9):963–971CrossRef
Zurück zum Zitat Le Blay P, Rakotonirainy H, Lagier JC, Raoult D, Puechal X, Pers YM (2014) A severe Whipple disease with an immune reconstitution inflammatory syndrome: an additional case of thalidomide efficiency. Jt Bone spine: Rev Rhum 81(3):260–262CrossRef Le Blay P, Rakotonirainy H, Lagier JC, Raoult D, Puechal X, Pers YM (2014) A severe Whipple disease with an immune reconstitution inflammatory syndrome: an additional case of thalidomide efficiency. Jt Bone spine: Rev Rhum 81(3):260–262CrossRef
Zurück zum Zitat Levenstein S, Prantera C, Varvo V, Scribano ML, Andreoli A, Luzi C et al (2000) Stress and exacerbation in ulcerative colitis: a prospective study of patients enrolled in remission. Am J Gastroenterol 95(5):1213–1220CrossRefPubMed Levenstein S, Prantera C, Varvo V, Scribano ML, Andreoli A, Luzi C et al (2000) Stress and exacerbation in ulcerative colitis: a prospective study of patients enrolled in remission. Am J Gastroenterol 95(5):1213–1220CrossRefPubMed
Zurück zum Zitat Lossos A, River Y, Eliakim A, Steiner I (1995) Neurologic aspects of inflammatory bowel disease. Neurol 45(3 Pt 1):416–421CrossRef Lossos A, River Y, Eliakim A, Steiner I (1995) Neurologic aspects of inflammatory bowel disease. Neurol 45(3 Pt 1):416–421CrossRef
Zurück zum Zitat Louis ED, Lynch T, Kaufmann P, Fahn S, Odel J (1996) Diagnostic guidelines in central nervous system Whipple‘s disease. Ann Neurol 40(4):561–568CrossRefPubMed Louis ED, Lynch T, Kaufmann P, Fahn S, Odel J (1996) Diagnostic guidelines in central nervous system Whipple‘s disease. Ann Neurol 40(4):561–568CrossRefPubMed
Zurück zum Zitat Luostarinen L, Himanen SL, Luostarinen M, Collin P, Pirttila T (2003) Neuromuscular and sensory disturbances in patients with well treated coeliac disease. J Neurol Neurosurg Psychiatry 74(4):490–494CrossRefPubMedPubMedCentral Luostarinen L, Himanen SL, Luostarinen M, Collin P, Pirttila T (2003) Neuromuscular and sensory disturbances in patients with well treated coeliac disease. J Neurol Neurosurg Psychiatry 74(4):490–494CrossRefPubMedPubMedCentral
Zurück zum Zitat Mahnel R, Marth T (2004) Progress, problems, and perspectives in diagnosis and treatment of Whipple’s disease. Clin Exp Med 4(1):39–43CrossRefPubMed Mahnel R, Marth T (2004) Progress, problems, and perspectives in diagnosis and treatment of Whipple’s disease. Clin Exp Med 4(1):39–43CrossRefPubMed
Zurück zum Zitat Manzel K, Tranel D, Cooper G (2000) Cognitive and behavioral abnormalities in a case of central nervous system Whipple disease. Arch Neurol 57(3):399–403CrossRefPubMed Manzel K, Tranel D, Cooper G (2000) Cognitive and behavioral abnormalities in a case of central nervous system Whipple disease. Arch Neurol 57(3):399–403CrossRefPubMed
Zurück zum Zitat Masuda H, Ishii U, Aoki N, Nakayama H, Sato F, Karube H et al (2002) Ulcerative colitis associated with Takayasu’s disease in two patients who received proctocolectomy. J Gastroenterol 37(4):297–302CrossRefPubMed Masuda H, Ishii U, Aoki N, Nakayama H, Sato F, Karube H et al (2002) Ulcerative colitis associated with Takayasu’s disease in two patients who received proctocolectomy. J Gastroenterol 37(4):297–302CrossRefPubMed
Zurück zum Zitat Menard DB, Haddad H, Blain JG, Beaudry R, Devroede G, Masse S (1976) Granulomatous myositis and myopathy associated with crohn’s colitis. N Engl J Med 295(15):818–819CrossRefPubMed Menard DB, Haddad H, Blain JG, Beaudry R, Devroede G, Masse S (1976) Granulomatous myositis and myopathy associated with crohn’s colitis. N Engl J Med 295(15):818–819CrossRefPubMed
Zurück zum Zitat Miehsler W, Reinisch W, Valic E, Osterode W, Tillinger W, Feichtenschlager T et al (2004) Is inflammatory bowel disease an independent and disease specific risk factor for thromboembolism? Gut 53(4):542–548CrossRefPubMedPubMedCentral Miehsler W, Reinisch W, Valic E, Osterode W, Tillinger W, Feichtenschlager T et al (2004) Is inflammatory bowel disease an independent and disease specific risk factor for thromboembolism? Gut 53(4):542–548CrossRefPubMedPubMedCentral
Zurück zum Zitat Moos V, Feurle GE, Schinnerling K, Geelhaar A, Friebel J, Allers K et al (2013) Immunopathology of immune reconstitution inflammatory syndrome in Whipple’s disease. J Immunol 190(5):2354–2361CrossRefPubMed Moos V, Feurle GE, Schinnerling K, Geelhaar A, Friebel J, Allers K et al (2013) Immunopathology of immune reconstitution inflammatory syndrome in Whipple’s disease. J Immunol 190(5):2354–2361CrossRefPubMed
Zurück zum Zitat Murai H, Tokunaga H, Kubo I, Kawajiri M, Iwaki T, Taniwaki T et al (2006) Myeloradiculitis caused by Cryptococcus neoformans infection in a patient with ulcerative colitis: a neuropathological study. J Neurol Sci 247(2):236–238CrossRefPubMed Murai H, Tokunaga H, Kubo I, Kawajiri M, Iwaki T, Taniwaki T et al (2006) Myeloradiculitis caused by Cryptococcus neoformans infection in a patient with ulcerative colitis: a neuropathological study. J Neurol Sci 247(2):236–238CrossRefPubMed
Zurück zum Zitat Nelson J, Barron MM, Riggs JE, Gutmann L, Schochet SS Jr (1986) Cerebral vasculitis and ulcerative colitis. Neurol 36(5):719–721CrossRef Nelson J, Barron MM, Riggs JE, Gutmann L, Schochet SS Jr (1986) Cerebral vasculitis and ulcerative colitis. Neurol 36(5):719–721CrossRef
Zurück zum Zitat Oldenburg B, Van Tuyl BA, van der Griend R, Fijnheer R, van Berge Henegouwen GP (2005) Risk factors for thromboembolic complications in inflammatory bowel disease: the role of hyperhomocysteinaemia. Dig Dis Sci 50(2):235–240CrossRefPubMed Oldenburg B, Van Tuyl BA, van der Griend R, Fijnheer R, van Berge Henegouwen GP (2005) Risk factors for thromboembolic complications in inflammatory bowel disease: the role of hyperhomocysteinaemia. Dig Dis Sci 50(2):235–240CrossRefPubMed
Zurück zum Zitat Panani AD, Grigoriadou M, Magira E, Roussos C, Raptis SA (2006) Perinuclear antineutrophil cytoplasmic antibody myeloperoxidase-positive vasculitis in association with ulcerative colitis. Clin Rheumatol 25(1):35–37CrossRefPubMed Panani AD, Grigoriadou M, Magira E, Roussos C, Raptis SA (2006) Perinuclear antineutrophil cytoplasmic antibody myeloperoxidase-positive vasculitis in association with ulcerative colitis. Clin Rheumatol 25(1):35–37CrossRefPubMed
Zurück zum Zitat Purrmann J, Arendt G, Cleveland S, Borchard F, Furst W, Gemsa R et al (1992) Association of Crohn’s disease and multiple sclerosis. Is there a common background? J Clin Gastroenterol 14(1):43–46CrossRefPubMed Purrmann J, Arendt G, Cleveland S, Borchard F, Furst W, Gemsa R et al (1992) Association of Crohn’s disease and multiple sclerosis. Is there a common background? J Clin Gastroenterol 14(1):43–46CrossRefPubMed
Zurück zum Zitat Qureshi JA, Staugaitis SM, Calabrese LH (2002) Neutrophilic myositis: an extra-intestinal manifestation of ulcerative colitis. J Clin Rheumatol 8(2):85–88CrossRefPubMed Qureshi JA, Staugaitis SM, Calabrese LH (2002) Neutrophilic myositis: an extra-intestinal manifestation of ulcerative colitis. J Clin Rheumatol 8(2):85–88CrossRefPubMed
Zurück zum Zitat Rashtak S, Ettore MW, Homburger HA, Murray JA (2008) Comparative usefulness of deamidated gliadin antibodies in the diagnosis of celiac disease. Clin Gastroenterol Hepatol 6(4):426–432; quiz 370CrossRefPubMedPubMedCentral Rashtak S, Ettore MW, Homburger HA, Murray JA (2008) Comparative usefulness of deamidated gliadin antibodies in the diagnosis of celiac disease. Clin Gastroenterol Hepatol 6(4):426–432; quiz 370CrossRefPubMedPubMedCentral
Zurück zum Zitat Reinshagen M, Folsch UR (2004) Extraintestinal manifestations in ulcerative colitis. Z Gastroenterol 42(9):1024–1028PubMed Reinshagen M, Folsch UR (2004) Extraintestinal manifestations in ulcerative colitis. Z Gastroenterol 42(9):1024–1028PubMed
Zurück zum Zitat Richard S, Fairise A, Lacour JC, Ducrocq X (2010) Cerebral venous thrombosis in inflammatory bowel diseases. Inflamm Bowel Dis 16(3):366–367CrossRefPubMed Richard S, Fairise A, Lacour JC, Ducrocq X (2010) Cerebral venous thrombosis in inflammatory bowel diseases. Inflamm Bowel Dis 16(3):366–367CrossRefPubMed
Zurück zum Zitat Romero Aroca P, Salvat Serra M, Perena Soriano F, Martinez Salcedo I (2001) Anterior optic neuritis do to ulcerative colitis. Arch Soc Esp Oftalmologia 76(3):189–191 Romero Aroca P, Salvat Serra M, Perena Soriano F, Martinez Salcedo I (2001) Anterior optic neuritis do to ulcerative colitis. Arch Soc Esp Oftalmologia 76(3):189–191
Zurück zum Zitat Scheid R, Teich N (2007) Neurologic manifestations of ulcerative colitis. Eur J Neurol 14(5):483–493CrossRefPubMed Scheid R, Teich N (2007) Neurologic manifestations of ulcerative colitis. Eur J Neurol 14(5):483–493CrossRefPubMed
Zurück zum Zitat van de Scheur MR, van der Waal RI, van Bodegraven AA, Volker-Dieben HJ, Starink TM, van der Waal I (2002) Cheilitis granulomatosa and optic neuropathy as rare extraintestinal manifestations of Crohn’s disease. J Clin Gastroenterol 34(5):557–559CrossRefPubMed van de Scheur MR, van der Waal RI, van Bodegraven AA, Volker-Dieben HJ, Starink TM, van der Waal I (2002) Cheilitis granulomatosa and optic neuropathy as rare extraintestinal manifestations of Crohn’s disease. J Clin Gastroenterol 34(5):557–559CrossRefPubMed
Zurück zum Zitat Schnider PJ, Reisinger EC, Gerschlager W, Muller C, Berger T, Krejs GJ et al (1996) Long-term follow-up in cerebral Whipple’s disease. Eur J Gastroenterol Hepatol 8(9):899–903PubMed Schnider PJ, Reisinger EC, Gerschlager W, Muller C, Berger T, Krejs GJ et al (1996) Long-term follow-up in cerebral Whipple’s disease. Eur J Gastroenterol Hepatol 8(9):899–903PubMed
Zurück zum Zitat Shen TC, Lebwohl B, Verma H, Kumta N, Tennyson C, Lewis S et al (2012) Peripheral neuropathic symptoms in celiac disease and inflammatory bowel disease. J Clin Neuromuscul Dis 13(3):137–145CrossRefPubMed Shen TC, Lebwohl B, Verma H, Kumta N, Tennyson C, Lewis S et al (2012) Peripheral neuropathic symptoms in celiac disease and inflammatory bowel disease. J Clin Neuromuscul Dis 13(3):137–145CrossRefPubMed
Zurück zum Zitat Tarabar D, Hirsch A, Rubin DT (2016) Vedolizumab in the treatment of Crohn’s disease. Expert Rev Gastroenterol Hepatol 10(3):283–290CrossRefPubMed Tarabar D, Hirsch A, Rubin DT (2016) Vedolizumab in the treatment of Crohn’s disease. Expert Rev Gastroenterol Hepatol 10(3):283–290CrossRefPubMed
Zurück zum Zitat Thomas CW Jr, Weinshenker BG, Sandborn WJ (2004) Demyelination during anti-tumor necrosis factor alpha therapy with infliximab for Crohn’s disease. Inflamm Bowel Dis 10(1):28–31CrossRefPubMed Thomas CW Jr, Weinshenker BG, Sandborn WJ (2004) Demyelination during anti-tumor necrosis factor alpha therapy with infliximab for Crohn’s disease. Inflamm Bowel Dis 10(1):28–31CrossRefPubMed
Zurück zum Zitat Watkinson G (1986) Sulphasalazine: a review of 40 years’ experience. Drugs 32(Suppl 1):1–11CrossRefPubMed Watkinson G (1986) Sulphasalazine: a review of 40 years’ experience. Drugs 32(Suppl 1):1–11CrossRefPubMed
Zurück zum Zitat Weber P, Husemann S, Vielhaber H, Zimmer KP, Nowak-Gottl U (1999) Coagulation and fibrinolysis in children, adolescents, and young adults with inflammatory bowel disease. J Pediatr Gastroenterol Nutr 28(4):418–422CrossRefPubMed Weber P, Husemann S, Vielhaber H, Zimmer KP, Nowak-Gottl U (1999) Coagulation and fibrinolysis in children, adolescents, and young adults with inflammatory bowel disease. J Pediatr Gastroenterol Nutr 28(4):418–422CrossRefPubMed
Zurück zum Zitat West J, Logan RF, Hill PG, Lloyd A, Lewis S, Hubbard R et al (2003) Seroprevalence, correlates, and characteristics of undetected coeliac disease in England. Gut 52(7):960–965CrossRefPubMedPubMedCentral West J, Logan RF, Hill PG, Lloyd A, Lewis S, Hubbard R et al (2003) Seroprevalence, correlates, and characteristics of undetected coeliac disease in England. Gut 52(7):960–965CrossRefPubMedPubMedCentral
Zurück zum Zitat Whipple G (1907) A hitherto undescribed disease characterized anatomically by deposits of fat and fatty acid in the intestinal and mesenteric lymphatic tissues. Bull Johns Hopkins Hosp 18:382–393 Whipple G (1907) A hitherto undescribed disease characterized anatomically by deposits of fat and fatty acid in the intestinal and mesenteric lymphatic tissues. Bull Johns Hopkins Hosp 18:382–393
Zurück zum Zitat WJ SRaS (Hrsg) (2004) Inflammatory bowel diseases: saunders WJ SRaS (Hrsg) (2004) Inflammatory bowel diseases: saunders
Zurück zum Zitat Yesilova Z, Naharci I, Uygun A, Ulas HU, Dagalp K (2006) Motor axonal polyneuropathy in the course of ulcerative colitis: a case report. Turk J Gastroenterol 17(1):58–61PubMed Yesilova Z, Naharci I, Uygun A, Ulas HU, Dagalp K (2006) Motor axonal polyneuropathy in the course of ulcerative colitis: a case report. Turk J Gastroenterol 17(1):58–61PubMed
Zurück zum Zitat Zois CD, Katsanos KH, Kosmidou M, Tsianos EV (2010) Neurologic manifestations in inflammatory bowel diseases: current knowledge and novel insights. J Crohn’s Colitis 4(2):115–124CrossRef Zois CD, Katsanos KH, Kosmidou M, Tsianos EV (2010) Neurologic manifestations in inflammatory bowel diseases: current knowledge and novel insights. J Crohn’s Colitis 4(2):115–124CrossRef
Metadaten
Titel
Neurologische Komplikationen entzündlicher Darmerkrankungen
verfasst von
Oliver Bachmann
Natascha Wehnert
Copyright-Jahr
2018
Verlag
Springer Berlin Heidelberg
DOI
https://doi.org/10.1007/978-3-662-55530-9_10