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28.11.2022 | Review Article

Quantification and Effectiveness of Vascularized Neck Lymph Node Transfer for Lymphedema: a Systematic Review and Meta-Analysis

verfasst von: Ishith Seth, Gabriella Bulloch, Damien Gibson, Nimish Seth, David J. Hunter-Smith, Warren M. Rozen

Erschienen in: Indian Journal of Surgery

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Abstract

This study aims to quantify the number of vascularized neck lymph nodes (VLNs) and postvascularized lymph node transfer (VLNT) and summarize the safety and efficacy of neck VLNT for treatment of lymphedema. PubMed, Web of Science, Google Scholar, and Cochrane CENTRAL databases were searched up to March 2022. PRISMA guidelines were adhered to, and the study was registered on PROSPERO. The primary outcome was the quantity of neck lymph nodes, and the secondary outcomes included postoperative cellulitis, Lymphedema Quality of Life Tool (LYMQOL), reduction of the extremity circumference, circumference differentiation, donor site morbidity, and lymphedema recurrence. The raw mean or proportion with a 95% confidence interval (CI) was calculated to conduct a single-arm meta-analysis. All analyses were performed using \(R\) software v4.0.3. Newcastle–Ottawa Scale was used to assess for quality of included studies. Eighteen studies comprising 510 patients were included in the single-arm meta-analysis. Mean neck VLNs were 3.80, 95% CI [2.48, 5.11], mean postoperative cellulitis was 0.70%, 95% CI [0.22, 1.18], mean postoperative LYMQOL was 6.84, 95% CI [5.39, 8.30], mean postoperative reduction of the extremity circumference 43.57%, 95% CI [27.81, 59.33], and mean circumference differentiation was 11.37%, 95% CI [7.51, 15.23]. The overall proportion of donor site morbidity events was 0.06, 95% CI [0.04, 0.11], and lymphedema recurrence was 0.12, 95% CI [0.05, 0.24]. The neck lymph node flap has an arsenal of lymph nodes present, carries no risk of iatrogenic edema, and has a low risk of other complications. Low donor site morbidity, patient satisfaction with the cosmetic scar, significant lymphedema reduction, and improvement of LYMQOL postoperatively are some positive outcomes that should be considered by surgeons.
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Literatur
1.
Zurück zum Zitat Park KE, Allam O, Chandler L, Mozzafari MA, Ly C, Lu X et al (2020) Surgical management of lymphedema: a review of current literature. Gland Surg 9(2):503 PubMedPubMedCentralCrossRef Park KE, Allam O, Chandler L, Mozzafari MA, Ly C, Lu X et al (2020) Surgical management of lymphedema: a review of current literature. Gland Surg 9(2):503 PubMedPubMedCentralCrossRef
2.
Zurück zum Zitat Warren AG, Brorson H, Borud LJ, Slavin SA (2007) Lymphedema: a comprehensive review. Ann Plast Surg 59(4):464–472 PubMedCrossRef Warren AG, Brorson H, Borud LJ, Slavin SA (2007) Lymphedema: a comprehensive review. Ann Plast Surg 59(4):464–472 PubMedCrossRef
3.
Zurück zum Zitat Moffatt CJ, Franks PJ, Doherty DC, Williams A, Badger C, Jeffs E et al (2003) Lymphoedema: an underestimated health problem. QJM 96(10):731–738 PubMedCrossRef Moffatt CJ, Franks PJ, Doherty DC, Williams A, Badger C, Jeffs E et al (2003) Lymphoedema: an underestimated health problem. QJM 96(10):731–738 PubMedCrossRef
4.
Zurück zum Zitat Soran A, Ozmen T, McGuire KP, Diego EJ, McAuliffe PF, Bonaventura M et al (2014) The importance of detection of subclinical lymphedema for the prevention of breast cancer-related clinical lymphedema after axillary lymph node dissection; a prospective observational study. Lymphat Res Biol 12(4):289–294 PubMedCrossRef Soran A, Ozmen T, McGuire KP, Diego EJ, McAuliffe PF, Bonaventura M et al (2014) The importance of detection of subclinical lymphedema for the prevention of breast cancer-related clinical lymphedema after axillary lymph node dissection; a prospective observational study. Lymphat Res Biol 12(4):289–294 PubMedCrossRef
5.
Zurück zum Zitat Cormier JN, Rourke L, Crosby M, Chang D, Armer J (2012) The surgical treatment of lymphedema: a systematic review of the contemporary literature (2004–2010). Ann Surg Oncol 19(2):642–651 PubMedCrossRef Cormier JN, Rourke L, Crosby M, Chang D, Armer J (2012) The surgical treatment of lymphedema: a systematic review of the contemporary literature (2004–2010). Ann Surg Oncol 19(2):642–651 PubMedCrossRef
6.
7.
Zurück zum Zitat Patel KM, Lin CY, Cheng MH (2015) From theory to evidence: long-term evaluation of the mechanism of action and flap integration of distal vascularized lymph node transfers. J Reconstr Microsurg 31(1):26–30 PubMedCrossRef Patel KM, Lin CY, Cheng MH (2015) From theory to evidence: long-term evaluation of the mechanism of action and flap integration of distal vascularized lymph node transfers. J Reconstr Microsurg 31(1):26–30 PubMedCrossRef
8.
Zurück zum Zitat Scaglioni MF, Fontein DB, Arvanitakis M, Giovanoli P (2017) Systematic review of lymphovenous anastomosis (LVA) for the treatment of lymphedema. Microsurgery 37(8):947–953 PubMedCrossRef Scaglioni MF, Fontein DB, Arvanitakis M, Giovanoli P (2017) Systematic review of lymphovenous anastomosis (LVA) for the treatment of lymphedema. Microsurgery 37(8):947–953 PubMedCrossRef
9.
Zurück zum Zitat Phan R, Seifman MA, Dhillon R, Lim P, Hunter-Smith DJ, Rozen WM (2020) Use of submental and submandibular free vascularized lymph node transfer for treatment of scrotal lymphedema: Report of two cases. Microsurgery 40(7):808–813 PubMedCrossRef Phan R, Seifman MA, Dhillon R, Lim P, Hunter-Smith DJ, Rozen WM (2020) Use of submental and submandibular free vascularized lymph node transfer for treatment of scrotal lymphedema: Report of two cases. Microsurgery 40(7):808–813 PubMedCrossRef
10.
Zurück zum Zitat Cheng M-H, Huang J-J, Nguyen DH, Saint-Cyr M, Zenn MR, Tan BK et al (2012) A novel approach to the treatment of lower extremity lymphedema by transferring a vascularized submental lymph node flap to the ankle. Gynecol Oncol 126(1):93–98 PubMedCrossRef Cheng M-H, Huang J-J, Nguyen DH, Saint-Cyr M, Zenn MR, Tan BK et al (2012) A novel approach to the treatment of lower extremity lymphedema by transferring a vascularized submental lymph node flap to the ankle. Gynecol Oncol 126(1):93–98 PubMedCrossRef
11.
Zurück zum Zitat Althubaiti GA, Crosby MA, Chang DW (2013) Vascularized supraclavicular lymph node transfer for lower extremity lymphedema treatment. Plast Reconstr Surg 131(1):133e-e135 PubMedCrossRef Althubaiti GA, Crosby MA, Chang DW (2013) Vascularized supraclavicular lymph node transfer for lower extremity lymphedema treatment. Plast Reconstr Surg 131(1):133e-e135 PubMedCrossRef
12.
Zurück zum Zitat Ciuce C, Seddiq F, Fodor M, Constantinescu D, Todoran M, Andercou A et al (2003) Omental free-tissue transfer: indications and results from personal experience. Microsurgery 23(3):198–205 PubMedCrossRef Ciuce C, Seddiq F, Fodor M, Constantinescu D, Todoran M, Andercou A et al (2003) Omental free-tissue transfer: indications and results from personal experience. Microsurgery 23(3):198–205 PubMedCrossRef
13.
Zurück zum Zitat Gerety PA, Pannucci CJ, Basta MN, Wang AR, Zhang P, Mies C et al (2016) Lymph node content of supraclavicular and thoracodorsal-based axillary flaps for vascularized lymph node transfer. J Vasc Surg Venous Lymphat Disord 4(1):80–87 PubMedCrossRef Gerety PA, Pannucci CJ, Basta MN, Wang AR, Zhang P, Mies C et al (2016) Lymph node content of supraclavicular and thoracodorsal-based axillary flaps for vascularized lymph node transfer. J Vasc Surg Venous Lymphat Disord 4(1):80–87 PubMedCrossRef
14.
Zurück zum Zitat Kwiecien GJ, Uygur S, Korn J, Gharb BB, Madajka M, Djohan R et al (2015) Vascularized axillary lymph node transfer: a novel model in the rat. Microsurgery 35(8):662–667 PubMedCrossRef Kwiecien GJ, Uygur S, Korn J, Gharb BB, Madajka M, Djohan R et al (2015) Vascularized axillary lymph node transfer: a novel model in the rat. Microsurgery 35(8):662–667 PubMedCrossRef
15.
Zurück zum Zitat Mardonado AA, Chen R, Chang DW (2017) The use of supraclavicular free flap with vascularized lymph node transfer for treatment of lymphedema: a prospective study of 100 consecutive cases. J Surg Oncol 115(1):68–71 CrossRef Mardonado AA, Chen R, Chang DW (2017) The use of supraclavicular free flap with vascularized lymph node transfer for treatment of lymphedema: a prospective study of 100 consecutive cases. J Surg Oncol 115(1):68–71 CrossRef
16.
Zurück zum Zitat Paulus VA, Winters H, Hummelink S, Schulten S, Ulrich DJ, Vasilic D (2020) Submental flap for vascularized lymph node transfer; a CTA-based study on lymph node distribution. J Surg Oncol 122(6):1226–1231 PubMedPubMedCentralCrossRef Paulus VA, Winters H, Hummelink S, Schulten S, Ulrich DJ, Vasilic D (2020) Submental flap for vascularized lymph node transfer; a CTA-based study on lymph node distribution. J Surg Oncol 122(6):1226–1231 PubMedPubMedCentralCrossRef
17.
Zurück zum Zitat Asuncion M-O, Chu S-Y, Huang Y-L, Lin C-Y, Cheng M-H. (2018) Accurate prediction of submental lymph nodes using magnetic resonance imaging for lymphedema surgery. Plastic and Reconstructive Surgery Global Open. 6(3). Asuncion M-O, Chu S-Y, Huang Y-L, Lin C-Y, Cheng M-H. (2018) Accurate prediction of submental lymph nodes using magnetic resonance imaging for lymphedema surgery. Plastic and Reconstructive Surgery Global Open. 6(3).
18.
Zurück zum Zitat Tzou CH, Meng S, Ines T, Reissig L, Pichler U, Steinbacher J et al (2017) Surgical anatomy of the vascularized submental lymph node flap: anatomic study of correlation of submental artery perforators and quantity of submental lymph node. J Surg Oncol 115(1):54–59 PubMedCrossRef Tzou CH, Meng S, Ines T, Reissig L, Pichler U, Steinbacher J et al (2017) Surgical anatomy of the vascularized submental lymph node flap: anatomic study of correlation of submental artery perforators and quantity of submental lymph node. J Surg Oncol 115(1):54–59 PubMedCrossRef
19.
Zurück zum Zitat Stroup DF, Berlin JA, Morton SC, Olkin I, Williamson GD, Rennie D et al (2000) Meta-analysis of observational studies in epidemiology: a proposal for reporting. JAMA 283(15):2008–2012 PubMedCrossRef Stroup DF, Berlin JA, Morton SC, Olkin I, Williamson GD, Rennie D et al (2000) Meta-analysis of observational studies in epidemiology: a proposal for reporting. JAMA 283(15):2008–2012 PubMedCrossRef
20.
Zurück zum Zitat Stang A (2010) Critical evaluation of the Newcastle-Ottawa scale for the assessment of the quality of nonrandomized studies in meta-analyses. Eur J Epidemiol 25(9):603–605 PubMedCrossRef Stang A (2010) Critical evaluation of the Newcastle-Ottawa scale for the assessment of the quality of nonrandomized studies in meta-analyses. Eur J Epidemiol 25(9):603–605 PubMedCrossRef
21.
Zurück zum Zitat Wang N (2018) How to conduct a meta-analysis of proportions in R: a comprehensive tutorial New York NY, John Jay College of Criminal Justice 62 Wang N (2018) How to conduct a meta-analysis of proportions in R: a comprehensive tutorial New York NY, John Jay College of Criminal Justice 62
22.
Zurück zum Zitat Akita S, Mitsukawa N, Kuriyama M, Kubota Y, Hasegawa M, Tokumoto H et al (2015) Comparison of vascularized supraclavicular lymph node transfer and lymphaticovenular anastomosis for advanced stage lower extremity lymphedema. Ann Plast Surg 74(5):573–579 PubMedCrossRef Akita S, Mitsukawa N, Kuriyama M, Kubota Y, Hasegawa M, Tokumoto H et al (2015) Comparison of vascularized supraclavicular lymph node transfer and lymphaticovenular anastomosis for advanced stage lower extremity lymphedema. Ann Plast Surg 74(5):573–579 PubMedCrossRef
23.
Zurück zum Zitat Aljaaly HA, Fries CA, Cheng M-H. (2019) Dorsal wrist placement for vascularized submental lymph node transfer significantly improves breast cancer–related lymphedema. Plastic and reconstructive surgery Global open. 7(2). Aljaaly HA, Fries CA, Cheng M-H. (2019) Dorsal wrist placement for vascularized submental lymph node transfer significantly improves breast cancer–related lymphedema. Plastic and reconstructive surgery Global open. 7(2).
24.
Zurück zum Zitat Chang TNJ, Lee CH, Lin JAJ, Cheng MH (2020) Morbidity of marginal mandibular nerve post vascularized submental lymph node flap transplantation. J Surg Oncol 122(8):1747–1754 PubMedCrossRef Chang TNJ, Lee CH, Lin JAJ, Cheng MH (2020) Morbidity of marginal mandibular nerve post vascularized submental lymph node flap transplantation. J Surg Oncol 122(8):1747–1754 PubMedCrossRef
25.
Zurück zum Zitat Cheng MH, Lin CY, Patel KM (2017) A prospective clinical assessment of anatomic variability of the submental vascularized lymph node flap. J Surg Oncol 115(1):43–47 PubMedCrossRef Cheng MH, Lin CY, Patel KM (2017) A prospective clinical assessment of anatomic variability of the submental vascularized lymph node flap. J Surg Oncol 115(1):43–47 PubMedCrossRef
26.
Zurück zum Zitat Chung J-H, Hwang Y-J, Park S-H, Yoon E-S. 2021 Preliminary outcomes of combined surgical approach for lower extremity lymphedema: supraclavicular lymph node transfer and lymphaticovenular anastomosis. J Plastic Surg Hand Surgery. 1–9. Chung J-H, Hwang Y-J, Park S-H, Yoon E-S. 2021 Preliminary outcomes of combined surgical approach for lower extremity lymphedema: supraclavicular lymph node transfer and lymphaticovenular anastomosis. J Plastic Surg Hand Surgery. 1–9.
27.
Zurück zum Zitat Gustafsson J, Chu S-Y, Chan W-H, Cheng M-H (2018) Correlation between quantity of transferred lymph nodes and outcome in vascularized submental lymph node flap transfer for lower limb lymphedema. Plast Reconstr Surg 142(4):1056–1063 PubMedCrossRef Gustafsson J, Chu S-Y, Chan W-H, Cheng M-H (2018) Correlation between quantity of transferred lymph nodes and outcome in vascularized submental lymph node flap transfer for lower limb lymphedema. Plast Reconstr Surg 142(4):1056–1063 PubMedCrossRef
28.
Zurück zum Zitat Ho OA, Lin C-Y, Pappalardo M, Cheng M-H. (2018) Comparisons of submental and groin vascularized lymph node flaps transfer for breast cancer-related lymphedema. Plastic and Reconstructive Surgery Global Open. 6(12). Ho OA, Lin C-Y, Pappalardo M, Cheng M-H. (2018) Comparisons of submental and groin vascularized lymph node flaps transfer for breast cancer-related lymphedema. Plastic and Reconstructive Surgery Global Open. 6(12).
29.
Zurück zum Zitat Liu H-L, Chung JC-K (2019) The lymph node content of supraclavicular lymph node flap a histological study on fresh human specimens. Lymphatic Res Biol 17(5):537–42 CrossRef Liu H-L, Chung JC-K (2019) The lymph node content of supraclavicular lymph node flap a histological study on fresh human specimens. Lymphatic Res Biol 17(5):537–42 CrossRef
30.
Zurück zum Zitat Koide S, Lin CY, Chen C, Cheng MH (2020) Long-term outcome of lower extremity lymphedema treated with vascularized lymph node flap transfer with or without venous complications. J Surg Oncol 121(1):129–137 PubMed Koide S, Lin CY, Chen C, Cheng MH (2020) Long-term outcome of lower extremity lymphedema treated with vascularized lymph node flap transfer with or without venous complications. J Surg Oncol 121(1):129–137 PubMed
31.
Zurück zum Zitat Maldonado AA, Chen R, Chang DW (2017) The use of supraclavicular free flap with vascularized lymph node transfer for treatment of lymphedema: a prospective study of 100 consecutive cases. J Surg Oncol 115(1):68–71 PubMedCrossRef Maldonado AA, Chen R, Chang DW (2017) The use of supraclavicular free flap with vascularized lymph node transfer for treatment of lymphedema: a prospective study of 100 consecutive cases. J Surg Oncol 115(1):68–71 PubMedCrossRef
32.
Zurück zum Zitat Poccia I, Lin CY, Cheng MH (2017) Platysma-sparing vascularized submental lymph node flap transfer for extremity lymphedema. J Surg Oncol 115(1):48–53 PubMedCrossRef Poccia I, Lin CY, Cheng MH (2017) Platysma-sparing vascularized submental lymph node flap transfer for extremity lymphedema. J Surg Oncol 115(1):48–53 PubMedCrossRef
33.
Zurück zum Zitat Sapountzis S, Ciudad P, Lim SY, Chilgar RM, Kiranantawat K, Nicoli F et al (2014) Modified Charles procedure and lymph node flap transfer for advanced lower extremity lymphedema. Microsurgery 34(6):439–447 PubMedCrossRef Sapountzis S, Ciudad P, Lim SY, Chilgar RM, Kiranantawat K, Nicoli F et al (2014) Modified Charles procedure and lymph node flap transfer for advanced lower extremity lymphedema. Microsurgery 34(6):439–447 PubMedCrossRef
34.
Zurück zum Zitat Sapountzis S, Singhal D, Rashid A, Meo D, Chen H-C (2014) Lymph node flap based on the right transverse cervical artery as a donor site for lymph node transfer. Ann Plast Surg 73(4):398–401 PubMedCrossRef Sapountzis S, Singhal D, Rashid A, Meo D, Chen H-C (2014) Lymph node flap based on the right transverse cervical artery as a donor site for lymph node transfer. Ann Plast Surg 73(4):398–401 PubMedCrossRef
35.
Zurück zum Zitat Visconti G, Tartaglione G, Bartoletti R, Salgarello M (2019) Compartimental harvesting of dual lymph node flap from the right supraclavicular area for the treatment of lower extremity lymphedema: a case series. J Plast Reconstr Aesthet Surg 72(2):211–215 PubMedCrossRef Visconti G, Tartaglione G, Bartoletti R, Salgarello M (2019) Compartimental harvesting of dual lymph node flap from the right supraclavicular area for the treatment of lower extremity lymphedema: a case series. J Plast Reconstr Aesthet Surg 72(2):211–215 PubMedCrossRef
36.
Zurück zum Zitat Keeley V, Crooks S, Locke J, Veigas D, Riches K, Hilliam R (2010) A quality of life measure for limb lymphoedema (LYMQOL). J Lymphoedema 5(1):26–37 Keeley V, Crooks S, Locke J, Veigas D, Riches K, Hilliam R (2010) A quality of life measure for limb lymphoedema (LYMQOL). J Lymphoedema 5(1):26–37
37.
Zurück zum Zitat Hassani C, Tran K, Palmer SL, Patel KM (2020) Vascularized lymph node transfer: a primer for the radiologist. Radiographics 40(4):1073–1089 PubMedCrossRef Hassani C, Tran K, Palmer SL, Patel KM (2020) Vascularized lymph node transfer: a primer for the radiologist. Radiographics 40(4):1073–1089 PubMedCrossRef
38.
Zurück zum Zitat Pannucci CJ, Gerety PA, Wang AR, Zhang P, Mies C, Kanchwala SK (2016) Feasibility of the internal mammary lymph node flap as a vascularized lymph node transfer: a cadaveric dissection study. Microsurgery 36(6):485–490 PubMedCrossRef Pannucci CJ, Gerety PA, Wang AR, Zhang P, Mies C, Kanchwala SK (2016) Feasibility of the internal mammary lymph node flap as a vascularized lymph node transfer: a cadaveric dissection study. Microsurgery 36(6):485–490 PubMedCrossRef
39.
Zurück zum Zitat Li Y, Dong R, Li Z, Wang L, Long X (2021) Intra-abdominal vascularized lymph node transfer for treatment of lymphedema: a systematic literature review and meta-analysis. Microsurgery 41(8):802–815 PubMedCrossRef Li Y, Dong R, Li Z, Wang L, Long X (2021) Intra-abdominal vascularized lymph node transfer for treatment of lymphedema: a systematic literature review and meta-analysis. Microsurgery 41(8):802–815 PubMedCrossRef
40.
Zurück zum Zitat Dayan JH, Dayan E, Kagen A, Cheng MH, Sultan M, Samson W et al (2014) The use of magnetic resonance angiography in vascularized groin lymph node transfer: an anatomic study. J Reconstr Microsurg 30(1):41–45 PubMedCrossRef Dayan JH, Dayan E, Kagen A, Cheng MH, Sultan M, Samson W et al (2014) The use of magnetic resonance angiography in vascularized groin lymph node transfer: an anatomic study. J Reconstr Microsurg 30(1):41–45 PubMedCrossRef
41.
Zurück zum Zitat Patel KM, Chu SY, Huang JJ, Wu CW, Lin CY, Cheng MH (2014) Preplanning vascularized lymph node transfer with duplex ultrasonography: an evaluation of 3 donor sites. Plast Reconstr Surg Glob Open 2(8):e193 PubMedPubMedCentralCrossRef Patel KM, Chu SY, Huang JJ, Wu CW, Lin CY, Cheng MH (2014) Preplanning vascularized lymph node transfer with duplex ultrasonography: an evaluation of 3 donor sites. Plast Reconstr Surg Glob Open 2(8):e193 PubMedPubMedCentralCrossRef
42.
Zurück zum Zitat Cook JA, Sasor SE, Tholpady SS, Chu MW (2018) Omental vascularized lymph node flap: a radiographic analysis. J Reconstr Microsurg 34(7):472–477 PubMedCrossRef Cook JA, Sasor SE, Tholpady SS, Chu MW (2018) Omental vascularized lymph node flap: a radiographic analysis. J Reconstr Microsurg 34(7):472–477 PubMedCrossRef
43.
Zurück zum Zitat Becker C, Vasile JV, Levine JL, Batista BN, Studinger RM, Chen CM et al (2012) Microlymphatic surgery for the treatment of iatrogenic lymphedema. Clin Plast Surg 39(4):385–398 PubMedCrossRef Becker C, Vasile JV, Levine JL, Batista BN, Studinger RM, Chen CM et al (2012) Microlymphatic surgery for the treatment of iatrogenic lymphedema. Clin Plast Surg 39(4):385–398 PubMedCrossRef
44.
Zurück zum Zitat Chang EI, Chu CK, Hanson SE, Selber JC, Hanasono MM, Schaverien MV (2020) Comprehensive overview of available donor sites for vascularized lymph node transfer. Plastic and Reconstructive Surgery Global Open. 8(3). Chang EI, Chu CK, Hanson SE, Selber JC, Hanasono MM, Schaverien MV (2020) Comprehensive overview of available donor sites for vascularized lymph node transfer. Plastic and Reconstructive Surgery Global Open. 8(3).
45.
Zurück zum Zitat Nguyen DH, Chou PY, Hsieh YH, Momeni A, Fang YHD, Patel KM et al (2016) Quantity of lymph nodes correlates with improvement in lymphatic drainage in treatment of hind limb lymphedema with lymph node flap transfer in rats. Microsurgery 36(3):239–245 PubMedCrossRef Nguyen DH, Chou PY, Hsieh YH, Momeni A, Fang YHD, Patel KM et al (2016) Quantity of lymph nodes correlates with improvement in lymphatic drainage in treatment of hind limb lymphedema with lymph node flap transfer in rats. Microsurgery 36(3):239–245 PubMedCrossRef
46.
Zurück zum Zitat Vignes S, Blanchard M, Yannoutsos A, Arrault M (2013) Complications of autologous lymph-node transplantation for limb lymphoedema. Eur J Vasc Endovasc Surg 45(5):516–520 PubMedCrossRef Vignes S, Blanchard M, Yannoutsos A, Arrault M (2013) Complications of autologous lymph-node transplantation for limb lymphoedema. Eur J Vasc Endovasc Surg 45(5):516–520 PubMedCrossRef
47.
Zurück zum Zitat Steinbacher J, Tinhofer IE, Meng S, Reissig LF, Placheta E, Roka-Palkovits J et al (2017) The surgical anatomy of the supraclavicular lymph node flap: a basis for the free vascularized lymph node transfer. J Surg Oncol 115(1):60–62 PubMedCrossRef Steinbacher J, Tinhofer IE, Meng S, Reissig LF, Placheta E, Roka-Palkovits J et al (2017) The surgical anatomy of the supraclavicular lymph node flap: a basis for the free vascularized lymph node transfer. J Surg Oncol 115(1):60–62 PubMedCrossRef
48.
Zurück zum Zitat Cheng M-H, Patel KM. (2015) Microsurgical Procedures: Vascularized lymph node transfer from the submental region. Principles and Practice of Lymphedema Surgery 138. Cheng M-H, Patel KM. (2015) Microsurgical Procedures: Vascularized lymph node transfer from the submental region. Principles and Practice of Lymphedema Surgery 138.
49.
Zurück zum Zitat Huang J-J (2015) Lymph node transfer to distal extremity. Springer, Lymphedema, pp 279–288 Huang J-J (2015) Lymph node transfer to distal extremity. Springer, Lymphedema, pp 279–288
50.
Zurück zum Zitat Lee M, McClure E, Reinertsen E, Granzow JW (2015) Lymphedema of the upper extremity following supraclavicular lymph node harvest. Plast Reconstr Surg 135(6):1079e-e1082 PubMedPubMedCentralCrossRef Lee M, McClure E, Reinertsen E, Granzow JW (2015) Lymphedema of the upper extremity following supraclavicular lymph node harvest. Plast Reconstr Surg 135(6):1079e-e1082 PubMedPubMedCentralCrossRef
51.
52.
Zurück zum Zitat Ward J, King I, Monroy-Iglesias M, Russell B, van Hemelrijck M, Ramsey K et al (2021) A meta-analysis of the efficacy of vascularised lymph node transfer in reducing limb volume and cellulitis episodes in patients with cancer treatment-related lymphoedema. Eur J Cancer 151:233–244 PubMedCrossRef Ward J, King I, Monroy-Iglesias M, Russell B, van Hemelrijck M, Ramsey K et al (2021) A meta-analysis of the efficacy of vascularised lymph node transfer in reducing limb volume and cellulitis episodes in patients with cancer treatment-related lymphoedema. Eur J Cancer 151:233–244 PubMedCrossRef
53.
Zurück zum Zitat Gillespie TC, Sayegh HE, Brunelle CL, Daniell KM, Taghian AG (2018) Breast cancer-related lymphedema: risk factors, precautionary measures, and treatments. Gland Surg 7(4):379 PubMedPubMedCentralCrossRef Gillespie TC, Sayegh HE, Brunelle CL, Daniell KM, Taghian AG (2018) Breast cancer-related lymphedema: risk factors, precautionary measures, and treatments. Gland Surg 7(4):379 PubMedPubMedCentralCrossRef
54.
Zurück zum Zitat Di Taranto G, Bolletta A, Chen SH, Losco L, Elia R, Cigna E et al (2021) A prospective study on combined lymphedema surgery: Gastroepiploic vascularized lymph nodes transfer and lymphaticovenous anastomosis followed by suction lipectomy. Microsurgery 41(1):34–43 PubMedCrossRef Di Taranto G, Bolletta A, Chen SH, Losco L, Elia R, Cigna E et al (2021) A prospective study on combined lymphedema surgery: Gastroepiploic vascularized lymph nodes transfer and lymphaticovenous anastomosis followed by suction lipectomy. Microsurgery 41(1):34–43 PubMedCrossRef
55.
Zurück zum Zitat Ciudad P, Maruccia M, Socas J, Lee MH, Chung KP, Constantinescu T et al (2017) The laparoscopic right gastroepiploic lymph node flap transfer for upper and lower limb lymphedema: Technique and outcomes. Microsurgery 37(3):197–205 PubMedCrossRef Ciudad P, Maruccia M, Socas J, Lee MH, Chung KP, Constantinescu T et al (2017) The laparoscopic right gastroepiploic lymph node flap transfer for upper and lower limb lymphedema: Technique and outcomes. Microsurgery 37(3):197–205 PubMedCrossRef
56.
Zurück zum Zitat Higgins JP, Thomas J, Chandler J, Cumpston M, Li T, Page MJ, et al. (2019) Cochrane handbook for systematic reviews of interventions: John Wiley & Sons Higgins JP, Thomas J, Chandler J, Cumpston M, Li T, Page MJ, et al. (2019) Cochrane handbook for systematic reviews of interventions: John Wiley & Sons
Metadaten
Titel
Quantification and Effectiveness of Vascularized Neck Lymph Node Transfer for Lymphedema: a Systematic Review and Meta-Analysis
verfasst von
Ishith Seth
Gabriella Bulloch
Damien Gibson
Nimish Seth
David J. Hunter-Smith
Warren M. Rozen
Publikationsdatum
28.11.2022
Verlag
Springer India
Erschienen in
Indian Journal of Surgery
Print ISSN: 0972-2068
Elektronische ISSN: 0973-9793
DOI
https://doi.org/10.1007/s12262-022-03627-6

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