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01.12.2022 | Original Article

Reference values of bone mineral density of proximal femur for Southeast Asian children and adolescents

verfasst von: Chonlada Trakulpark, Teerarat Manpayak, Praewvarin Weerakulwattana, Julaporn Pooliam, Pairunyar Nakavachara

Erschienen in: Archives of Osteoporosis | Ausgabe 1/2022

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Abstract

Summary

Bone mineral density (BMD) of the proximal femur helps evaluate bone density in children with reduced mechanical loading of the lower extremities. This study provides the first reference values of bone mineral density of proximal femur according to age and sex for Southeast Asian children and adolescents.

Objectives

The study aimed to (1) establish normative data of BMD of the proximal femur (femoral neck and total hip), measured by dual-energy X-ray absorptiometry (DXA), for healthy Thai children aged 5 to 18 years and (2) ascertain the relationships between BMD, growth, and puberty.

Methods

Proximal femur scans of 170 boys and 191 girls obtained from DXA (Lunar Prodigy Pro, GE, and software enCORE version 7.53) were un-analyzed and then re-analyzed with the upgraded software enCORE version 17 SP2 for BMD assessment. The bone mineral apparent density of the femoral neck (FNBMAD) was calculated.

Results

Sex and Tanner stage-specific BMD normative data were generated. BMD values of the femoral neck and total hip increased with age and pubertal progression. FNBMAD values were not markedly influenced by age and puberty. Using multiple linear regression analysis, age and weight affected FNBMD and total hip BMD in boys and girls, but height and Tanner stage only influenced girls. Age did not significantly influence FNBMAD in either sex. Tanner stage weakly influenced FNBMAD only in boys.

Conclusions

We established normative reference data for BMD of the proximal femur measured by DXA in Thai children aged 5 to 18 years. Our reference data will help clinicians and researchers assess and interpret the BMD of the proximal femur for Southeast Asian children.

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Titel: Reference values of bone mineral density of proximal femur for Southeast Asian children and adolescents
verfasst von: Chonlada Trakulpark
Teerarat Manpayak
Praewvarin Weerakulwattana
Julaporn Pooliam
Pairunyar Nakavachara
Publikationsdatum: 01.12.2022
Verlag: Springer London
Erschienen in: Archives of Osteoporosis / Ausgabe 1/2022
Print ISSN: 1862-3522
Elektronische ISSN: 1862-3514
DOI: https://doi.org/10.1007/s11657-022-01184-9

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Reference values of bone mineral density of proximal femur for Southeast Asian children and adolescents

Abstract

Summary

Objectives

Methods

Results

Conclusions

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Live-Webinar: Aktuelle Leitlinien bei Herz-Kreislauf-Erkrankungen

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Abstract

Summary

Objectives

Methods

Results

Conclusions

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