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04.03.2021 | Strahlentherapie | CME

Chirurgische Behandlung und Strahlentherapie von Hirnmetastasen

verfasst von: Univ.-Prof. Dr. Jan P. Boström, Kathleen Jetschke, Univ.-Prof. Dr. Kirsten Schmieder, Univ.-Prof. Dr. Irenäus A. Adamietz

Erschienen in: Die Onkologie | Ausgabe 4/2021

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Zusammenfassung

In dieser Arbeit sollen die Grundsätze der interdisziplinären Behandlung von Hirnmetastasen skizziert werden. Die interdisziplinäre Behandlung wird bestimmt durch die klinische Situation, anatomische Gegebenheiten und die Tumorentität. Sie hat eine Reduktion der Toxizität im Fokus. Zur Diagnostik von Hirnmetastasen werden Magnetresonanztomographie, Computertomographie (CT) und Positronenemissionstomographie-CT verwendet. Bei zugänglichen, symptomatischen Metastasen wird die Neurochirurgie eingesetzt. Bei umschriebenen, auch multiplen, jedoch chirurgisch schlecht erreichbaren Metastasen kommt die Radiochirurgie zum Einsatz. Die Teilhirnbestrahlung wird, wenn möglich, einer Ganzhirnbestrahlung vorgezogen. Eine Schonung des Hippocampus bei Ganzhirnbestrahlung reduziert die Therapietoxizität. In Notsituationen leisten Steroide einen effektiven Beitrag, eine neurochirurgische Intervention ist eventuell lebensrettend. Die Möglichkeiten einer medikamentösen Systemtherapie nehmen zu.
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Metadaten
Titel
Chirurgische Behandlung und Strahlentherapie von Hirnmetastasen
verfasst von
Univ.-Prof. Dr. Jan P. Boström
Kathleen Jetschke
Univ.-Prof. Dr. Kirsten Schmieder
Univ.-Prof. Dr. Irenäus A. Adamietz
Publikationsdatum
04.03.2021
Verlag
Springer Medizin
Erschienen in
Die Onkologie / Ausgabe 4/2021
Print ISSN: 2731-7226
Elektronische ISSN: 2731-7234
DOI
https://doi.org/10.1007/s00761-021-00913-y

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