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Erschienen in: Lasers in Medical Science 9/2020

07.03.2020 | Original Article

Study of transcranial photobiomodulation at 945-nm wavelength: anxiety and depression

verfasst von: Flávio Klinpovous Kerppers, Kesia Maria Mangoni Gonçalves dos Santos, Maria Elvira Ribeiro Cordeiro, Mário César da Silva Pereira, Danilo Barbosa, André Alexandre Pezzini, Luiza Ferreira Cunha, Maiara Fonseca, Ketlin Bragnholo, Afonso Shiguemi Inoue Salgado, Ivo Ilvan Kerppers

Erschienen in: Lasers in Medical Science | Ausgabe 9/2020

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Abstract

Transcranial photobiomodulation is an innovative method for the stimulation of neural activity which consists of the exposure of neural tissue to low-level light irradiance. In the present study, light-emitting diodes (LEDs) were used as light source due to their practicality and low cost. The objective was to analyze the effects of transcranial photobiomodulation using 945-nm LED in university students with anxiety and depression. Sample was composed of 22 individuals (17–25 years of age) divided into 2 groups of 11. LED group was treated with 945-nm LEDs for 1 min and 25 s (9.35 J/cm2), while in the placebo group, the device was off when placed in contact with the frontal bone for the same amount of time as in treatment group. Participants were evaluated at baseline and after 30 days with the hospital anxiety and depression scale (HADS), the faces test, the designs test, and the grip strength test. On the HADS for anxiety, the mean PAB, PAA, PhAB, and PhAA were 13.89 ± 3.55, 12.82 ± 3.18, 10.75 ± 2.49, and 6.66 ± 2.50 points, respectively. In the HADS for depression, the mean for the PDB group was 13.89 ± 3.55 points, in the PhDB group 12.82 ± 3.18 points, in the PDA group 10.75 ± 2.49 points, and in the PhDA group 6.66 ± 2.50 points. In the PA and PD groups, mean values of 8.0 ± 1.5 and 8.9 ± 1.26 scores were obtained, but did not reach significance; however, between PA and PhD analysis, a significance level of p = 0.0003 was obtained. The 945-nm LED transcranial photobiomodulation improves brain activity and may clinically decrease anxiety and depression.
Literatur
1.
Zurück zum Zitat Carmo LS et al (2016) Stress into university students impacts the learning quality. J Psychol Psychother 6(2):1–4 Carmo LS et al (2016) Stress into university students impacts the learning quality. J Psychol Psychother 6(2):1–4
2.
Zurück zum Zitat Leite CD et al (2016) Representações da ansiedade e medo de atletas universitários. Rev Brasil Psicol Esporte 6(1):1–11 Leite CD et al (2016) Representações da ansiedade e medo de atletas universitários. Rev Brasil Psicol Esporte 6(1):1–11
4.
Zurück zum Zitat Hirsh CD et al (2015) Coping strategies of nursing students for dealing with university stress. Rev Brasil Enfermagem 68(5):501–508 Hirsh CD et al (2015) Coping strategies of nursing students for dealing with university stress. Rev Brasil Enfermagem 68(5):501–508
5.
6.
Zurück zum Zitat Oliveira C, Varela A, Rodrigues P, Esteves J, Henriques C, Ribeiro A (2016) Programas de prevenção para ansiedade e depressão: Avaliação da percepção dos Estudantes Universitários. Revista Interações 42:96–111 Oliveira C, Varela A, Rodrigues P, Esteves J, Henriques C, Ribeiro A (2016) Programas de prevenção para ansiedade e depressão: Avaliação da percepção dos Estudantes Universitários. Revista Interações 42:96–111
7.
Zurück zum Zitat Gazalle FK, Hallal PC, Lima MS (2004) Depressão na população idosa: os médicos estão investigando? Rev Bras Psiquiatr 26(3):145–149 Gazalle FK, Hallal PC, Lima MS (2004) Depressão na população idosa: os médicos estão investigando? Rev Bras Psiquiatr 26(3):145–149
8.
Zurück zum Zitat Kanaya T, Yonekawa M (1990) Regional cerebral blood flow in depression. Jpn J Psvchol Neural 44:571–576 Kanaya T, Yonekawa M (1990) Regional cerebral blood flow in depression. Jpn J Psvchol Neural 44:571–576
9.
Zurück zum Zitat Ávila R, Bottino CM (2006) Atualização sobre alterações cognitivas em idosos com síndrome depressiva Cognitive changes update among elderly with depressive syndrome. Rev Bras Psiquiatr 28(4):316–320 Ávila R, Bottino CM (2006) Atualização sobre alterações cognitivas em idosos com síndrome depressiva Cognitive changes update among elderly with depressive syndrome. Rev Bras Psiquiatr 28(4):316–320
12.
Zurück zum Zitat Hamblin MR, de Sousa MVP, Agrawal T (2016) Handbook of low-level laser therapy. Pan Stanford Publishing Pte. Ltd., Singapore Hamblin MR, de Sousa MVP, Agrawal T (2016) Handbook of low-level laser therapy. Pan Stanford Publishing Pte. Ltd., Singapore
16.
Zurück zum Zitat Tedford CE, DeLapp S, Jacques S, Anders J (2015) Quantitative analysis of transcranial and intraparenchymal light penetration in human cadaver brain tissue. Lasers Surg Med 47:312–322 Tedford CE, DeLapp S, Jacques S, Anders J (2015) Quantitative analysis of transcranial and intraparenchymal light penetration in human cadaver brain tissue. Lasers Surg Med 47:312–322
22.
Zurück zum Zitat Ferreira-Rodrigues CF (2012) Avaliando a memória por meio da visualização da imagem de rostos. Psico-USF, Bragança Paulista Ferreira-Rodrigues CF (2012) Avaliando a memória por meio da visualização da imagem de rostos. Psico-USF, Bragança Paulista
23.
Zurück zum Zitat Charchat H, Nitrini R, Caramelli P, Sameshima K (2001) Investigação de Marcadores Clínicos dos Estágios Iniciais da Doença de Alzheimer com Testes Neuropsicológicos Computadorizados. Psicologia 14(2):305–316 Charchat H, Nitrini R, Caramelli P, Sameshima K (2001) Investigação de Marcadores Clínicos dos Estágios Iniciais da Doença de Alzheimer com Testes Neuropsicológicos Computadorizados. Psicologia 14(2):305–316
27.
Zurück zum Zitat Jiang J et al (2004) Exploring the influence of depressive symptoms on physical disability: a cohort study of elderly in Beijing, China. Qual Life Res 13:1337–1346 Jiang J et al (2004) Exploring the influence of depressive symptoms on physical disability: a cohort study of elderly in Beijing, China. Qual Life Res 13:1337–1346
30.
Zurück zum Zitat Raji MA, Kuo YF, Snih SA, Markides KS, Kristen PM, Ottnbacher KJ (2005) Cognitive status, muscle strength, and subsequent disability in older Mexican Americans. J Am Geriatr Soc 53:1462–1468 Raji MA, Kuo YF, Snih SA, Markides KS, Kristen PM, Ottnbacher KJ (2005) Cognitive status, muscle strength, and subsequent disability in older Mexican Americans. J Am Geriatr Soc 53:1462–1468
31.
Zurück zum Zitat Amaral CA et al (2015) Association of handgrip strength with self-reported diseases in adults in Rio Branco, Acre State, Brazil: a population-based study. Cad Saude Publica 31(6):1313–1325 Amaral CA et al (2015) Association of handgrip strength with self-reported diseases in adults in Rio Branco, Acre State, Brazil: a population-based study. Cad Saude Publica 31(6):1313–1325
32.
Zurück zum Zitat Rogers SD, Jarrott SE (2008) Cognitive impairment and effects on upper body strength of adults with dementia. J Aging Phys Act 16:61–68 Rogers SD, Jarrott SE (2008) Cognitive impairment and effects on upper body strength of adults with dementia. J Aging Phys Act 16:61–68
33.
Zurück zum Zitat Chwen-Yng S, Jau-Hong L, Tsui-Hsien C, Kuang-Fang C, Yue-Tung S (1994) Grip strength in different positions of elbow and shoulder. Arch Phys Med Aehabil 75:812–815 Chwen-Yng S, Jau-Hong L, Tsui-Hsien C, Kuang-Fang C, Yue-Tung S (1994) Grip strength in different positions of elbow and shoulder. Arch Phys Med Aehabil 75:812–815
44.
Zurück zum Zitat Hirschl M, Katzenschlager R, Francesconi C, Kundi M (2004) Low level laser therapy in primary Raynaud's phenomenon—results of a placebo controlled, double blind intervention study. J Rheumatol 31(12):2408–2412 Hirschl M, Katzenschlager R, Francesconi C, Kundi M (2004) Low level laser therapy in primary Raynaud's phenomenon—results of a placebo controlled, double blind intervention study. J Rheumatol 31(12):2408–2412
Metadaten
Titel
Study of transcranial photobiomodulation at 945-nm wavelength: anxiety and depression
verfasst von
Flávio Klinpovous Kerppers
Kesia Maria Mangoni Gonçalves dos Santos
Maria Elvira Ribeiro Cordeiro
Mário César da Silva Pereira
Danilo Barbosa
André Alexandre Pezzini
Luiza Ferreira Cunha
Maiara Fonseca
Ketlin Bragnholo
Afonso Shiguemi Inoue Salgado
Ivo Ilvan Kerppers
Publikationsdatum
07.03.2020
Verlag
Springer London
Erschienen in
Lasers in Medical Science / Ausgabe 9/2020
Print ISSN: 0268-8921
Elektronische ISSN: 1435-604X
DOI
https://doi.org/10.1007/s10103-020-02983-7