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Erschienen in: Die Diabetologie 4/2023

08.05.2023 | Typ-2-Diabetes | DDG Praxisempfehlungen

Adipositas und Diabetes

verfasst von: Prof. Dr. med. Jens Aberle, Anne Lautenbach, Svenja Meyhöfer, Sebastian M. Meyhöfer, Markus Menzen, Lars Selig, Matthias Blüher

Erschienen in: Die Diabetologie | Ausgabe 4/2023

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Auf der Webseite der Deutschen Diabetes Gesellschaft (https://​www.​deutsche-diabetes-gesellschaft.​de/​behandlung/​leitlinien) befinden sich alle PDFs zum kostenlosen Download. …
Literatur
1.
Zurück zum Zitat Lindström J, Louheranta A, Mannelin M et al (2003) The Finnish Diabetes Prevention Study (DPS): Lifestyle intervention and 3‑year results on diet and physical activity. Diabetes Care 26:3230–3236CrossRefPubMed Lindström J, Louheranta A, Mannelin M et al (2003) The Finnish Diabetes Prevention Study (DPS): Lifestyle intervention and 3‑year results on diet and physical activity. Diabetes Care 26:3230–3236CrossRefPubMed
2.
Zurück zum Zitat Knowler WC, Barrett-Connor E, Fowler SE et al (2002) Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin. N Engl J Med 346:393–403CrossRefPubMed Knowler WC, Barrett-Connor E, Fowler SE et al (2002) Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin. N Engl J Med 346:393–403CrossRefPubMed
3.
Zurück zum Zitat Lean MEJ, Powrie JK, Anderson AS et al (1990) Obesity, weight loss and prognosis in type 2 diabetes. Diabet Med 7:228–233CrossRefPubMed Lean MEJ, Powrie JK, Anderson AS et al (1990) Obesity, weight loss and prognosis in type 2 diabetes. Diabet Med 7:228–233CrossRefPubMed
4.
Zurück zum Zitat Williamson DF, Thompson TJ, Thun M et al (2000) Intentional weight loss and mortality among overweight individuals with diabetes. Diabetes Care 23:1499–1504CrossRefPubMed Williamson DF, Thompson TJ, Thun M et al (2000) Intentional weight loss and mortality among overweight individuals with diabetes. Diabetes Care 23:1499–1504CrossRefPubMed
5.
Zurück zum Zitat Wing RR, Bahnson JL, Bray GA et al (2010) Long-term effects of a lifestyle intervention on weight and cardiovascular risk factors in individuals with type 2 diabetes mellitus: Four-year results of the look AHEAD trial. Arch Intern Med 170:1566–1575PubMed Wing RR, Bahnson JL, Bray GA et al (2010) Long-term effects of a lifestyle intervention on weight and cardiovascular risk factors in individuals with type 2 diabetes mellitus: Four-year results of the look AHEAD trial. Arch Intern Med 170:1566–1575PubMed
6.
Zurück zum Zitat Eeg-Olofsson K, Cederholm J, Nilsson PM et al (2009) Risk of cardiovascular disease and mortality in overweight and obese patients with type 2 diabetes: An observational study in 13,087 patients. Diabetologia 52:65–73CrossRefPubMed Eeg-Olofsson K, Cederholm J, Nilsson PM et al (2009) Risk of cardiovascular disease and mortality in overweight and obese patients with type 2 diabetes: An observational study in 13,087 patients. Diabetologia 52:65–73CrossRefPubMed
7.
Zurück zum Zitat Buse JB, Wexler DJ, Tsapas A et al (2020) 2019 update to: Management of hyperglycemia in type 2 diabetes, 2018. A consensus report by the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD). Diabetes Care 43:487–493CrossRefPubMed Buse JB, Wexler DJ, Tsapas A et al (2020) 2019 update to: Management of hyperglycemia in type 2 diabetes, 2018. A consensus report by the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD). Diabetes Care 43:487–493CrossRefPubMed
8.
Zurück zum Zitat Wang Z, Hoy WE (2004) Waist circumference, body mass index, hip circumference and waist-to-hip ratio as predictors of cardiovascular disease in Aboriginal people. Eur J Clin Nutr 58:888–893CrossRefPubMed Wang Z, Hoy WE (2004) Waist circumference, body mass index, hip circumference and waist-to-hip ratio as predictors of cardiovascular disease in Aboriginal people. Eur J Clin Nutr 58:888–893CrossRefPubMed
9.
Zurück zum Zitat Pischon T, Boeing H, Hoffmann K et al (2008) General and abdominal adiposity and risk of death in Europe. N Engl J Med 359:2105–2120CrossRefPubMed Pischon T, Boeing H, Hoffmann K et al (2008) General and abdominal adiposity and risk of death in Europe. N Engl J Med 359:2105–2120CrossRefPubMed
10.
Zurück zum Zitat Evert AB, Dennison M, Gardner CD et al (2019) Nutrition therapy for adults with diabetes or prediabetes: A consensus report. Diabetes Care 42:731–754CrossRefPubMedPubMedCentral Evert AB, Dennison M, Gardner CD et al (2019) Nutrition therapy for adults with diabetes or prediabetes: A consensus report. Diabetes Care 42:731–754CrossRefPubMedPubMedCentral
11.
Zurück zum Zitat Reynolds AN, Akerman AP, Mann J (2020) Dietary fibre and whole grains in diabetes management: Systematic review and meta-analyses. PLoS Med 17:e1003053CrossRefPubMedPubMedCentral Reynolds AN, Akerman AP, Mann J (2020) Dietary fibre and whole grains in diabetes management: Systematic review and meta-analyses. PLoS Med 17:e1003053CrossRefPubMedPubMedCentral
12.
Zurück zum Zitat Landgraf R, Aberle J, Birkenfeld AL et al (2019) Therapy of type 2 diabetes. Exp Clin Endocrinol Diabetes 127:S73–S92CrossRefPubMed Landgraf R, Aberle J, Birkenfeld AL et al (2019) Therapy of type 2 diabetes. Exp Clin Endocrinol Diabetes 127:S73–S92CrossRefPubMed
13.
Zurück zum Zitat Lean ME, Leslie WS, Barnes AC et al (2018) Primary care-led weight management for remission of type 2 diabetes (DiRECT): an open-label, cluster-randomised trial. Lancet 391:541–551CrossRefPubMed Lean ME, Leslie WS, Barnes AC et al (2018) Primary care-led weight management for remission of type 2 diabetes (DiRECT): an open-label, cluster-randomised trial. Lancet 391:541–551CrossRefPubMed
14.
Zurück zum Zitat Gregg EW, Chen H, Wagenknecht LE et al (2012) Association of an intensive lifestyle intervention with remission of type 2 diabetes. JAMA 308:2489–2496CrossRefPubMedPubMedCentral Gregg EW, Chen H, Wagenknecht LE et al (2012) Association of an intensive lifestyle intervention with remission of type 2 diabetes. JAMA 308:2489–2496CrossRefPubMedPubMedCentral
15.
Zurück zum Zitat Nationale VersorgungsLeitlinie (NVL) Typ– Diabetes. 1. Aufl. Nationale VersorgungsLeitlinie (NVL) Typ– Diabetes. 1. Aufl.
16.
Zurück zum Zitat Kay SJ, Fiatarone Singh MA (2006) The influence of physical activity on abdominal fat: A systematic review of the literature. Obes Rev 7:183–200CrossRefPubMed Kay SJ, Fiatarone Singh MA (2006) The influence of physical activity on abdominal fat: A systematic review of the literature. Obes Rev 7:183–200CrossRefPubMed
18.
Zurück zum Zitat Vilsbøll T, Christensen M, Junker AE et al (2012) Effects of glucagon-like peptide‑1 receptor agonists on weight loss: Systematic review and meta-analyses of randomised controlled trials. BMJ 344:d7771CrossRefPubMedPubMedCentral Vilsbøll T, Christensen M, Junker AE et al (2012) Effects of glucagon-like peptide‑1 receptor agonists on weight loss: Systematic review and meta-analyses of randomised controlled trials. BMJ 344:d7771CrossRefPubMedPubMedCentral
19.
Zurück zum Zitat Pi-Sunyer X, Astrup A, Fujioka K et al (2015) A randomized, controlled trial of 3.0 mg of liraglutide in weight management. N Engl J Med 373:11–22CrossRefPubMed Pi-Sunyer X, Astrup A, Fujioka K et al (2015) A randomized, controlled trial of 3.0 mg of liraglutide in weight management. N Engl J Med 373:11–22CrossRefPubMed
20.
Zurück zum Zitat Wilding JPH, Batterham RL, Calanna S et al (2021) Once-weekly semaglutide in adults with overweight or obesity. N Engl J Med 384:989–1002CrossRefPubMed Wilding JPH, Batterham RL, Calanna S et al (2021) Once-weekly semaglutide in adults with overweight or obesity. N Engl J Med 384:989–1002CrossRefPubMed
21.
Zurück zum Zitat Rubino DM, Greenway FL, Khalid U et al (2022) Effect of weekly subcutaneous semaglutide vs daily Liraglutide on body weight in adults with overweight or obesity without diabetes: the STEP 8 randomized clinical trial. JAMA 327:138–150CrossRefPubMedPubMedCentral Rubino DM, Greenway FL, Khalid U et al (2022) Effect of weekly subcutaneous semaglutide vs daily Liraglutide on body weight in adults with overweight or obesity without diabetes: the STEP 8 randomized clinical trial. JAMA 327:138–150CrossRefPubMedPubMedCentral
22.
Zurück zum Zitat Muscelli E, Mari A, Casolaro A et al (2008) Separate impact of obesity and glucose tolerance on the incretin effect in normal subjects and type 2 diabetic patients. Diabetes 57:1340–1348CrossRefPubMed Muscelli E, Mari A, Casolaro A et al (2008) Separate impact of obesity and glucose tolerance on the incretin effect in normal subjects and type 2 diabetic patients. Diabetes 57:1340–1348CrossRefPubMed
23.
Zurück zum Zitat Liu C, Li C, Cai X et al (2021) Discovery of a novel GLP-1/GIP dual receptor agonist CY‑5 as long-acting hypoglycemic, anti-obesity agent. Bioorg Chem 106:104492CrossRefPubMed Liu C, Li C, Cai X et al (2021) Discovery of a novel GLP-1/GIP dual receptor agonist CY‑5 as long-acting hypoglycemic, anti-obesity agent. Bioorg Chem 106:104492CrossRefPubMed
24.
Zurück zum Zitat Gautier JF, Choukem SP, Girard J (2008) Physiology of incretins (GIP and GLP-1) and abnormalities in type 2 diabetes. Diabetes Metab 34:S65–S72CrossRefPubMed Gautier JF, Choukem SP, Girard J (2008) Physiology of incretins (GIP and GLP-1) and abnormalities in type 2 diabetes. Diabetes Metab 34:S65–S72CrossRefPubMed
25.
Zurück zum Zitat Alvarez E, Martínez MD, Roncero I et al (2005) The expression of GLP‑1 receptor mRNA and protein allows the effect of GLP‑1 on glucose metabolism in the human hypothalamus and brainstem. J Neurochem 92:798–806CrossRefPubMed Alvarez E, Martínez MD, Roncero I et al (2005) The expression of GLP‑1 receptor mRNA and protein allows the effect of GLP‑1 on glucose metabolism in the human hypothalamus and brainstem. J Neurochem 92:798–806CrossRefPubMed
26.
Zurück zum Zitat Rosenstock J, Wysham C, Frías JP et al (2021) Efficacy and safety of a novel dual GIP and GLP‑1 receptor agonist tirzepatide in patients with type 2 diabetes (SURPASS-1): a double-blind, randomised, phase 3 trial. Lancet 398:143–155CrossRefPubMed Rosenstock J, Wysham C, Frías JP et al (2021) Efficacy and safety of a novel dual GIP and GLP‑1 receptor agonist tirzepatide in patients with type 2 diabetes (SURPASS-1): a double-blind, randomised, phase 3 trial. Lancet 398:143–155CrossRefPubMed
27.
Zurück zum Zitat Frías JP, Davies MJ, Rosenstock J et al (2021) Tirzepatide versus semaglutide once weekly in patients with type 2 diabetes. N Engl J Med 385:503–515CrossRefPubMed Frías JP, Davies MJ, Rosenstock J et al (2021) Tirzepatide versus semaglutide once weekly in patients with type 2 diabetes. N Engl J Med 385:503–515CrossRefPubMed
28.
Zurück zum Zitat Jastreboff AM, Aronne LJ, Ahmad NN et al (2022) Tirzepatide once weekly for the treatment of obesity. N Engl J Med 387:205–216CrossRefPubMed Jastreboff AM, Aronne LJ, Ahmad NN et al (2022) Tirzepatide once weekly for the treatment of obesity. N Engl J Med 387:205–216CrossRefPubMed
29.
Zurück zum Zitat Rubino F, Nathan DM, Eckel RH et al (2016) Metabolic surgery in the treatment algorithm for type 2 diabetes: A joint statement by international diabetes organizations. Diabetes Care 39:861–877CrossRefPubMed Rubino F, Nathan DM, Eckel RH et al (2016) Metabolic surgery in the treatment algorithm for type 2 diabetes: A joint statement by international diabetes organizations. Diabetes Care 39:861–877CrossRefPubMed
30.
Zurück zum Zitat S3-Leitlinie (2018) Chirurgie der Adipositas und metabolischer Erkrankungen. Version 2.3 S3-Leitlinie (2018) Chirurgie der Adipositas und metabolischer Erkrankungen. Version 2.3
31.
Zurück zum Zitat Longitudinal Assessment of Bariatric Surgery (LABS) Consortium, Flum DR, Belle SH, King WC et al (2009) Perioperative safety in the longitudinal assessment of bariatric surgery. N Engl J Med 361:445–454CrossRef Longitudinal Assessment of Bariatric Surgery (LABS) Consortium, Flum DR, Belle SH, King WC et al (2009) Perioperative safety in the longitudinal assessment of bariatric surgery. N Engl J Med 361:445–454CrossRef
32.
Zurück zum Zitat Birkmeyer NJO, Dimick JB, Share D et al (2010) Hospital complication rates with bariatric surgery in Michigan. JAMA 304:435–442CrossRefPubMed Birkmeyer NJO, Dimick JB, Share D et al (2010) Hospital complication rates with bariatric surgery in Michigan. JAMA 304:435–442CrossRefPubMed
33.
Zurück zum Zitat Aberle J, Reining F, Dannheim V et al (2012) Metformin after bariatric surgery—An acid problem. Exp Clin Endocrinol Diabetes 120:152–153CrossRefPubMed Aberle J, Reining F, Dannheim V et al (2012) Metformin after bariatric surgery—An acid problem. Exp Clin Endocrinol Diabetes 120:152–153CrossRefPubMed
Metadaten
Titel
Adipositas und Diabetes
verfasst von
Prof. Dr. med. Jens Aberle
Anne Lautenbach
Svenja Meyhöfer
Sebastian M. Meyhöfer
Markus Menzen
Lars Selig
Matthias Blüher
Publikationsdatum
08.05.2023
Verlag
Springer Medizin
Erschienen in
Die Diabetologie / Ausgabe 4/2023
Print ISSN: 2731-7447
Elektronische ISSN: 2731-7455
DOI
https://doi.org/10.1007/s11428-023-01037-0

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