Skip to main content
Erschienen in:
Buchtitelbild

2017 | Typ-2-Diabetes | OriginalPaper | Buchkapitel

1. Typ-2-Diabetes mellitus und Depression bei älteren Menschen

verfasst von : Frank Petrak

Erschienen in: Ältere Menschen mit Diabetes und Depression

Verlag: Springer Berlin Heidelberg

Zusammenfassung

Menschen mit Diabetes haben ein erhöhtes Depressionsrisiko – insbesondere bei älteren Patienten stellt dies eine lebensbedrohliche Komorbidität dar. Depressionssymptome sind assoziiert mit Hyperglykämie, mikro- und makrovaskulären Diabeteskomplikationen sowie einer deutlich erhöhten Mortalität. Auffallend ist dabei, dass älteren Patienten bereits bei leichten depressiven Symptomen eine deutliche Risikoerhöhung für Komplikationen und Mortalität zeigen. Die besondere Situation älterer Menschen erfordert ein ihrer Lebenssituation und Leistungsfähigkeit angepasstes therapeutisches Vorgehen, damit auch in dieser Lebensphase depressive Störungen gut behandelt werden können. Obwohl die Komorbidität von Depressionen und Diabetes im Forschungskontext umfassend behandelt wird, liegen Therapiestudien zur Behandlung von Depressionen bei älteren Diabetespatienten kaum vor. In dem vorliegenden Therapiemanual wird ein diabetesspezifisches verhaltenstherapeutisches Konzept vorgestellt, welches speziell zur Behandlung von älteren Menschen mit Diabetes und Depression konzipiert wurde und seine Wirksamkeit im Rahmen einer groß angelegten randomisierten kontrollierten Multicenterstudie belegt hat.
Literatur
Zurück zum Zitat Anderson RJ, Freedland KE, Clouse RE, Lustman PJ (2001) The prevalence of comorbid depression in adults with diabetes: a meta-analysis. Diabetes Care; 24(6):1069–1078 Anderson RJ, Freedland KE, Clouse RE, Lustman PJ (2001) The prevalence of comorbid depression in adults with diabetes: a meta-analysis. Diabetes Care; 24(6):1069–1078
Zurück zum Zitat Atlantis E, Fahey P, Foster J (2014) Collaborative care for comorbid depression and diabetes: a systematic review and meta-analysis. BMJ Open 4(4):e004706 Atlantis E, Fahey P, Foster J (2014) Collaborative care for comorbid depression and diabetes: a systematic review and meta-analysis. BMJ Open 4(4):e004706
Zurück zum Zitat Baumeister H, Hutter N, Bengel J (2014) Psychological and pharmacological interventions for depression in patients with diabetes mellitus – an abridged Cochrane review. Diabetic Medicine; 31(7):773-786 Baumeister H, Hutter N, Bengel J (2014) Psychological and pharmacological interventions for depression in patients with diabetes mellitus – an abridged Cochrane review. Diabetic Medicine; 31(7):773-786
Zurück zum Zitat Black SA, Markides KS, Ray LA (2003) Depression Predicts Increased Incidence of Adverse Health Outcomes in Older Mexican Americans With Type 2 Diabetes. Diabetes Care 26(10):2822–2828 Black SA, Markides KS, Ray LA (2003) Depression Predicts Increased Incidence of Adverse Health Outcomes in Older Mexican Americans With Type 2 Diabetes. Diabetes Care 26(10):2822–2828
Zurück zum Zitat Bot M, Pouwer F, Zuidersma M, van Melle JP, de Jonge P (2012) Association of coexisting diabetes and depression with mortality after myocardial infarction. Diabetes Care 35(3):503–509 Bot M, Pouwer F, Zuidersma M, van Melle JP, de Jonge P (2012) Association of coexisting diabetes and depression with mortality after myocardial infarction. Diabetes Care 35(3):503–509
Zurück zum Zitat Bruce DG, Casey G, Davis WA, et al. (2006) Vascular depression in older people with diabetes. Diabetologia 49(12):2828–2836 Bruce DG, Casey G, Davis WA, et al. (2006) Vascular depression in older people with diabetes. Diabetologia 49(12):2828–2836
Zurück zum Zitat Ciechanowski PS, Katon WJ, Russo JE (2000) Depression and diabetes: impact of depressive symptoms on adherence, function, and costs. Arch Intern Med 160(21):3278–3285 Ciechanowski PS, Katon WJ, Russo JE (2000) Depression and diabetes: impact of depressive symptoms on adherence, function, and costs. Arch Intern Med 160(21):3278–3285
Zurück zum Zitat De Groot M, Anderson R, Freedland K, Clouse R, Lustman P (2001) Association of depression and diabetes complications: a meta-analysis. Psychosom Med 63(4):619–630 De Groot M, Anderson R, Freedland K, Clouse R, Lustman P (2001) Association of depression and diabetes complications: a meta-analysis. Psychosom Med 63(4):619–630
Zurück zum Zitat Egede LE, Nietert PJ, Zheng D (2005) Depression and All-Cause and Coronary Heart Disease Mortality Among Adults With and Without Diabetes. Diabetes Care 28(6):1339–1345 Egede LE, Nietert PJ, Zheng D (2005) Depression and All-Cause and Coronary Heart Disease Mortality Among Adults With and Without Diabetes. Diabetes Care 28(6):1339–1345
Zurück zum Zitat Fisher L, Skaff MM, Mullan JT, Arean P, Glasgow R, Masharani U (2008) A longitudinal study of affective and anxiety disorders, depressive affect and diabetes distress in adults with Type 2 diabetes. Diabet Med 25(9):1096–1101 Fisher L, Skaff MM, Mullan JT, Arean P, Glasgow R, Masharani U (2008) A longitudinal study of affective and anxiety disorders, depressive affect and diabetes distress in adults with Type 2 diabetes. Diabet Med 25(9):1096–1101
Zurück zum Zitat Golden SH, Lazo M, Carnethon M, et al. (2008) Examining a bidirectional association between depressive symptoms and diabetes. Jama 299(23):275–219 Golden SH, Lazo M, Carnethon M, et al. (2008) Examining a bidirectional association between depressive symptoms and diabetes. Jama 299(23):275–219
Zurück zum Zitat Hautzinger M (2009) Depression im Alter: Erkennen, bewältigen, behandeln. Ein kognitiv-verhaltenstherapeutisches Gruppenprogramm. Beltz, Weinheim Hautzinger M (2009) Depression im Alter: Erkennen, bewältigen, behandeln. Ein kognitiv-verhaltenstherapeutisches Gruppenprogramm. Beltz, Weinheim
Zurück zum Zitat Hautzinger M (2013) Kognitive Verhaltenstherapie bei Depressionen. Beltz, Weinheim Hautzinger M (2013) Kognitive Verhaltenstherapie bei Depressionen. Beltz, Weinheim
Zurück zum Zitat Hermanns N, Kulzer B, Krichbaum M, Kubiak T, Haak T (2006) How to screen for depression and emotional problems in patients with diabetes: comparison of screening characteristics of depression questionnaires, measurement of diabetes-specific emotional problems and standard clinical assessment. Diabetologia 49(3):469–477 Hermanns N, Kulzer B, Krichbaum M, Kubiak T, Haak T (2006) How to screen for depression and emotional problems in patients with diabetes: comparison of screening characteristics of depression questionnaires, measurement of diabetes-specific emotional problems and standard clinical assessment. Diabetologia 49(3):469–477
Zurück zum Zitat Icks A, Kruse J, Dragano N, et al. (2008) Are symptoms of depression more common in diabetes? Results from the Heinz Nixdorf Recall study. Diabet Med 25(11):1330–1336 Icks A, Kruse J, Dragano N, et al. (2008) Are symptoms of depression more common in diabetes? Results from the Heinz Nixdorf Recall study. Diabet Med 25(11):1330–1336
Zurück zum Zitat Katon W, Simon G, Russo J, et al. (2004) Quality of depression care in a population-based sample of patients with diabetes and major depression. Med Care 42(12):1222–1229 Katon W, Simon G, Russo J, et al. (2004) Quality of depression care in a population-based sample of patients with diabetes and major depression. Med Care 42(12):1222–1229
Zurück zum Zitat Knol MJ, Twisk JW, Beekman AT, Heine RJ, Snoek FJ, Pouwer F (2006) Depression as a risk factor for the onset of type 2 diabetes mellitus. A meta-analysis. Diabetologia 49(5):837–845 Knol MJ, Twisk JW, Beekman AT, Heine RJ, Snoek FJ, Pouwer F (2006) Depression as a risk factor for the onset of type 2 diabetes mellitus. A meta-analysis. Diabetologia 49(5):837–845
Zurück zum Zitat Kühner C, Weber I (2001) Depression vorbeugen. Ein Gruppenprogramm nach R.F. Muňos. Hogrefe, Göttingen Kühner C, Weber I (2001) Depression vorbeugen. Ein Gruppenprogramm nach R.F. Muňos. Hogrefe, Göttingen
Zurück zum Zitat Lin EH, Katon W, Von Korff M, et al. (2004) Relationship of depression and diabetes self-care, medication adherence, and preventive care. Diabetes Care 27(9):2154–2160 Lin EH, Katon W, Von Korff M, et al. (2004) Relationship of depression and diabetes self-care, medication adherence, and preventive care. Diabetes Care 27(9):2154–2160
Zurück zum Zitat Lustman PJ, Anderson RJ, Freedland KE, de Groot M, Carney RM, Clouse RE (2000) Depression and poor glycemic control: a meta-analytic review of the literature. Diabetes Care 23(7): 934–942 Lustman PJ, Anderson RJ, Freedland KE, de Groot M, Carney RM, Clouse RE (2000) Depression and poor glycemic control: a meta-analytic review of the literature. Diabetes Care 23(7): 934–942
Zurück zum Zitat Lustman PJ, Griffith LS, Freedland KE, Kissel SS, Clouse RE (1998) Cognitive behavior therapy for depression in type 2 diabetes mellitus. A randomized, controlled trial. Ann Intern Med 129(8):613–621 Lustman PJ, Griffith LS, Freedland KE, Kissel SS, Clouse RE (1998) Cognitive behavior therapy for depression in type 2 diabetes mellitus. A randomized, controlled trial. Ann Intern Med 129(8):613–621
Zurück zum Zitat Mezuk B, Eaton WW, Albrecht S, Golden SH (2008) Depression and type 2 diabetes over the lifespan: a meta-analysis. Diabetes Care 31(12):2383–2390 Mezuk B, Eaton WW, Albrecht S, Golden SH (2008) Depression and type 2 diabetes over the lifespan: a meta-analysis. Diabetes Care 31(12):2383–2390
Zurück zum Zitat Moulton CD, Pickup JC, Ismail K (2015a) The link between depression and diabetes: the search for shared mechanisms. Lancet Diabetes Endocrinol 3(6):461–471 Moulton CD, Pickup JC, Ismail K (2015a) The link between depression and diabetes: the search for shared mechanisms. Lancet Diabetes Endocrinol 3(6):461–471
Zurück zum Zitat Moulton CD, Stewart R, Amiel SA, Laake JP, Ismail K. (2015b) Factors associated with cognitive impairment in patients with newly diagnosed type 2 diabetes: a cross-sectional study. Aging Ment Health 11:1–8 Moulton CD, Stewart R, Amiel SA, Laake JP, Ismail K. (2015b) Factors associated with cognitive impairment in patients with newly diagnosed type 2 diabetes: a cross-sectional study. Aging Ment Health 11:1–8
Zurück zum Zitat Moussavi S, Chatterji S, Verdes E, Tandon A, Patel V, Ustun B (2007) Depression, chronic diseases, and decrements in health: results from the World Health Surveys. Lancet 370(9590):851–858 Moussavi S, Chatterji S, Verdes E, Tandon A, Patel V, Ustun B (2007) Depression, chronic diseases, and decrements in health: results from the World Health Surveys. Lancet 370(9590):851–858
Zurück zum Zitat Musselman DL, Betan E, Larsen H, Phillips LS (2003) Relationship of depression to diabetes types 1 and 2: epidemiology, biology, and treatment. Biol Psychiatry 54(3):317–329 Musselman DL, Betan E, Larsen H, Phillips LS (2003) Relationship of depression to diabetes types 1 and 2: epidemiology, biology, and treatment. Biol Psychiatry 54(3):317–329
Zurück zum Zitat Nefs G, Pouwer F, Denollet J, Kramer H, Wijnands-van Gent CJ, Pop VJ (2012) Suboptimal glycemic control in type 2 diabetes: a key role for anhedonia? J Psychiatr Res 46(4):549–554 Nefs G, Pouwer F, Denollet J, Kramer H, Wijnands-van Gent CJ, Pop VJ (2012) Suboptimal glycemic control in type 2 diabetes: a key role for anhedonia? J Psychiatr Res 46(4):549–554
Zurück zum Zitat Petrak F, Herpertz S (2013) Psychodiabetologie. Springer, Heidelberg Petrak F, Herpertz S (2013) Psychodiabetologie. Springer, Heidelberg
Zurück zum Zitat Petrak F, Herpertz S, Albus C, et al. (2013) Study protocol of the Diabetes and Depression Study (DAD): a multi-center randomized controlled trial to compare the efficacy of a diabetes-specific cognitive behavioral group therapy versus sertraline in patients with major depression and poorly controlled diabetes mellitus. BMC Psychiatry 13:206 Petrak F, Herpertz S, Albus C, et al. (2013) Study protocol of the Diabetes and Depression Study (DAD): a multi-center randomized controlled trial to compare the efficacy of a diabetes-specific cognitive behavioral group therapy versus sertraline in patients with major depression and poorly controlled diabetes mellitus. BMC Psychiatry 13:206
Zurück zum Zitat Petrak F, Baumeister H, Skinner TC, Brown A, Holt RI (2015a) Depression and diabetes: treatment and health-care delivery. Lancet Diabetes Endocrinol 3(6):472–485 Petrak F, Baumeister H, Skinner TC, Brown A, Holt RI (2015a) Depression and diabetes: treatment and health-care delivery. Lancet Diabetes Endocrinol 3(6):472–485
Zurück zum Zitat Petrak F, Herpertz S, Albus C, et al. (2015b) Cognitive Behavioral Therapy Versus Sertraline in Patients With Depression and Poorly Controlled Diabetes: The Diabetes and Depression (DAD) Study: A Randomized Controlled Multicenter Trial. Diabetes Care 38(5):767–775 Petrak F, Herpertz S, Albus C, et al. (2015b) Cognitive Behavioral Therapy Versus Sertraline in Patients With Depression and Poorly Controlled Diabetes: The Diabetes and Depression (DAD) Study: A Randomized Controlled Multicenter Trial. Diabetes Care 38(5):767–775
Zurück zum Zitat Richardson LK, Egede LE, Mueller M (2008a) Effect of race/ethnicity and persistent recognition of depression on mortality in elderly men with type 2 diabetes and depression. Diabetes Care 31(5):880–881 Richardson LK, Egede LE, Mueller M (2008a) Effect of race/ethnicity and persistent recognition of depression on mortality in elderly men with type 2 diabetes and depression. Diabetes Care 31(5):880–881
Zurück zum Zitat Richardson LK, Egede LE, Mueller M, Echols CL, Gebregziabher M (2008b) Longitudinal effects of depression on glycemic control in veterans with Type 2 diabetes. Gen Hosp Psychiatry 30(6):509–514 Richardson LK, Egede LE, Mueller M, Echols CL, Gebregziabher M (2008b) Longitudinal effects of depression on glycemic control in veterans with Type 2 diabetes. Gen Hosp Psychiatry 30(6):509–514
Zurück zum Zitat Rustad JK, Musselman DL, Nemeroff CB (2011) The relationship of depression and diabetes: pathophysiological and treatment implications. Psychoneuroendocrinology 36(9):1276–1286 Rustad JK, Musselman DL, Nemeroff CB (2011) The relationship of depression and diabetes: pathophysiological and treatment implications. Psychoneuroendocrinology 36(9):1276–1286
Zurück zum Zitat Sneed JR, Roose SP, Sackeim HA (2006) Vascular depression: A distinct diagnostic subtype? Biol Psychiatry 60(12):1295–1298 Sneed JR, Roose SP, Sackeim HA (2006) Vascular depression: A distinct diagnostic subtype? Biol Psychiatry 60(12):1295–1298
Zurück zum Zitat Stuart MJ, Baune BT (2012) Depression and type 2 diabetes: inflammatory mechanisms of a psychoneuroendocrine co-morbidity. Neurosci Biobehav Rev 36(1):658–676 Stuart MJ, Baune BT (2012) Depression and type 2 diabetes: inflammatory mechanisms of a psychoneuroendocrine co-morbidity. Neurosci Biobehav Rev 36(1):658–676
Zurück zum Zitat van der Feltz-Cornelis CM, Nuyen J, Stoop C, et al. (2010) Effect of interventions for major depressive disorder and significant depressive symptoms in patients with diabetes mellitus: a systematic review and meta-analysis. Gen Hosp Psychiatry 32(4):380–395 van der Feltz-Cornelis CM, Nuyen J, Stoop C, et al. (2010) Effect of interventions for major depressive disorder and significant depressive symptoms in patients with diabetes mellitus: a systematic review and meta-analysis. Gen Hosp Psychiatry 32(4):380–395
Zurück zum Zitat Weyerer S, Eifflaender-Gorfer S, Kohler L, et al. (2008) Prevalence and risk factors for depression in non-demented primary care attenders aged 75 years and older. J Affect Disord 111(2–3):153–163 Weyerer S, Eifflaender-Gorfer S, Kohler L, et al. (2008) Prevalence and risk factors for depression in non-demented primary care attenders aged 75 years and older. J Affect Disord 111(2–3):153–163
Metadaten
Titel
Typ-2-Diabetes mellitus und Depression bei älteren Menschen
verfasst von
Frank Petrak
Copyright-Jahr
2017
Verlag
Springer Berlin Heidelberg
DOI
https://doi.org/10.1007/978-3-662-52911-9_1

Praxisempfehlungen der Deutschen Diabetes Gesellschaft

Kurz, prägnant und aktuell: Die Praxisempfehlungen der Deutschen Diabetes Gesellschaft.