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Current Infectious Disease Reports

Erschienen in:

13.06.2022 | HIV/AIDS (C Yoon, Section Editor)

What’s Old Is New: the Evolution of Lymphogranuloma Venereum Proctitis in Persons Living with HIV

verfasst von: Ronnie M. Gravett, Jeanne Marrazzo

Erschienen in: Current Infectious Disease Reports | Ausgabe 8/2022

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Abstract

Purpose of Review

Lymphogranuloma venereum (LGV) has re-emerged as a consequential anorectal sexually transmitted infection with high burden among persons living with HIV, especially men who have sex with men (MSM).

Recent Findings

Surveillance programs are limited without widely available LGV-specific diagnostics, but LGV prevalence is becoming increasingly recognized as it spreads globally. The LGV epidemic remains high among MSM living with HIV and is now shifting to include more HIV-negative MSM. LGV testing of asymptomatic persons at high risk will increase case finding and potential for earlier intervention. Doxycycline remains the guideline-directed treatment of choice, but recent data may support shorter duration or even use of azithromycin as alternatives.

Summary

While the burden of LGV is appreciated as a significant cause of proctitis, especially among MSM living with HIV, lack of accessible diagnostics limits our understanding of actual incidence and its impact on the HIV epidemic. Future directions should include assay validation for widespread use and rigorous clinical trials to examine treatment durations based on symptom burden.

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Titel: What’s Old Is New: the Evolution of Lymphogranuloma Venereum Proctitis in Persons Living with HIV
verfasst von: Ronnie M. Gravett
Jeanne Marrazzo
Publikationsdatum: 13.06.2022
Verlag: Springer US
Erschienen in: Current Infectious Disease Reports / Ausgabe 8/2022
Print ISSN: 1523-3847
Elektronische ISSN: 1534-3146
DOI: https://doi.org/10.1007/s11908-022-00781-6

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What’s Old Is New: the Evolution of Lymphogranuloma Venereum Proctitis in Persons Living with HIV

Abstract

Purpose of Review

Recent Findings

Summary

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Springer Medizin

Abstract

Purpose of Review

Recent Findings

Summary

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Leitlinien kompakt für die Innere Medizin

Neu im Fachgebiet Innere Medizin

Niedriger diastolischer Blutdruck erhöht Risiko für schwere kardiovaskuläre Komplikationen

Therapiestart mit Blutdrucksenkern erhöht Frakturrisiko

Adjuvante Immuntherapie verlängert Leben bei RCC

Alectinib verbessert krankheitsfreies Überleben bei ALK-positivem NSCLC

Update Innere Medizin